Research Output

2020

Accumulated nocturnal hypoxemia predict arterial endothelial function in patients with sleep-disordered breathing with or without chronic heart failure

Sawatari, H., Chishaki, A., Nishizaka, M., Miyazono, M., Tokunou, T., Magota, C., Yamamoto, U., Handa, S. S. & Ando, S. I., Jun 1 2020, In : Heart and Vessels. 35, 6, p. 800-807 8 p.

Research output: Contribution to journalArticle

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: A lectin microarray-based study

Takayama, H., Ohta, M., Iwashita, Y., Uchida, H., Shitomi, Y., Yada, K. & Inomata, M., Mar 6 2020, In : BMC Cancer. 20, 1, 192.

Research output: Contribution to journalArticle

Open Access

A novel C1 inhibitor gene mutation in a family with hereditary angioedema: Use of genetic analysis to facilitate early diagnosis

Yokoyama, K., Horiuchi, T., Hashimura, C. & Yoshida, A., Jan 2020, In : Allergology International. 69, 1, p. 148-149 2 p.

Research output: Contribution to journalLetter

Open Access

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Takeishi, K., Collin de l'Hortet, A., Wang, Y., Handa, K., Guzman-Lepe, J., Matsubara, K., Morita, K., Jang, S., Haep, N., Florentino, R. M., Yuan, F., Fukumitsu, K., Tobita, K., Sun, W., Franks, J., Delgado, E. R., Shapiro, E. M., Fraunhoffer, N. A., Duncan, A. W., Yagi, H. & 3 others, Mashimo, T., Fox, I. J. & Soto-Gutierrez, A., Jun 2 2020, In : Cell Reports. 31, 9, 107711.

Research output: Contribution to journalArticle

Open Access
Open Access

A unified simulation model for understanding the diversity of cancer evolution

Niida, A., Hasegawa, T., Innan, H., Shibata, T., Mimori, K. & Miyano, S., Jan 1 2020, In : PeerJ. 2020, 4, 8842.

Research output: Contribution to journalArticle

Open Access

BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis

Chen, Q., Lei, J. H., Bao, J., Wang, H., Hao, W., Li, L., Peng, C., Masuda, T., Miao, K., Xu, J., Xu, X. & Deng, C. X., Mar 1 2020, In : Advanced Science. 7, 6, 1903616.

Research output: Contribution to journalArticle

Open Access

Changes in magnetic resonance imaging signal intensity in predicting complications during acute phase osteoporotic vertebral fractures

Iida, K., Kumamaru, H., Saito, T. & Harimaya, K., Sep 1 2020, In : Journal of Orthopaedics. 21, p. 309-313 5 p.

Research output: Contribution to journalArticle

Circulating PD-1 mRNA in Peripheral Blood is a Potential Biomarker for Predicting Survival of Breast Cancer Patients

Noda, M., Masuda, T., Ito, S., Tobo, T., Kitagawa, A., Hu, Q., Shimizu, D., Eguchi, H., Etoh, T., Ohno, S., Inomata, M. & Mimori, K., Jan 1 2020, (Accepted/In press) In : Annals of Surgical Oncology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Current status of endoscopic surgery in Japan: The 14th National Survey of Endoscopic Surgery by the Japan Society for Endoscopic Surgery

Inomata, M., Shiroshita, H., Uchida, H., Bandoh, T., Akira, S., Yamaguchi, S., Kurokawa, Y., Seki, Y., Eguchi, S., Wada, N., Takiguchi, S., Ieiri, S., Endo, S., Iwazaki, M., Sato, Y., Tamaki, Y., Kitamura, K., Tabata, M., Kanayama, H., Mimata, H. & 8 others, Hasegawa, T., Takahashi, H., Onishi, K., Uemura, T., Hashizume, M., Matsumoto, S., Kitano, S. & Watanabe, M., Jan 1 2020, In : Asian journal of endoscopic surgery. 13, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Drug repositioning in cancer: The current situation in Japan

Masuda, T., Tsuruda, Y., Matsumoto, Y., Uchida, H., Nakayama, K. I. & Mimori, K., Apr 1 2020, In : Cancer Science. 111, 4, p. 1039-1046 8 p.

Research output: Contribution to journalReview article

Open Access

GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor-suppressor gene TGFβR2 in colorectal cancer

Nambara, S., Masuda, T., Kobayashi, Y., Sato, K., Tobo, T., Koike, K., Noda, M., Ogawa, Y., Kuroda, Y., Ito, S., Eguchi, H., Sugimachi, K. & Mimori, K., Feb 1 2020, In : Cancer Science. 111, 2, p. 343-355 13 p.

Research output: Contribution to journalArticle

Open Access

Homeostatic milieu induces production of deoxyribonuclease 1-like 3 from myeloid cells

Inokuchi, S., Mitoma, H., Kawano, S., Nakano, S., Ayano, M., Kimoto, Y., Akahoshi, M., Arinobu, Y., Tsukamoto, H., Akashi, K., Horiuchi, T. & Niiro, H., Apr 15 2020, In : Journal of Immunology. 204, 8, p. 2088-2097 10 p.

Research output: Contribution to journalArticle

Impact of middle hepatic artery reconstruction after living donor liver transplantation using the left lobe

Harada, N., Yoshizumi, T., Uchiyama, H., Ikegami, T., Itoh, S., Takeishi, K., Toshima, T., Nagao, Y., Yoshiya, S. & Mori, M., Jun 1 2020, In : Clinical Transplantation. 34, 6, e13850.

Research output: Contribution to journalArticle

KIF15 Εxpression in Τumor-associated Μonocytes Ιs a prognostic biomarker in hepatocellular carcinoma

Kitagawa, A., Masuda, T., Takahashi, J., Tobo, T., Noda, M., Kuroda, Y., Hu, Q., Kouyama, Y., Kobayashi, Y., Kuramitsu, S., Sato, K., Fujii, A., Yoshikawa, Y., Wakiyama, H., Shimizu, D., Tsuruda, Y., Eguchi, H., Doki, Y., Mori, M. & Mimori, K., Jan 1 2020, In : Cancer Genomics and Proteomics. 17, 2, p. 141-149 9 p.

Research output: Contribution to journalArticle

Open Access

Living-Donor Liver Transplantation for Patients With Extrahepatic Malignancy: A Series of 14 Patients in a Single Institution

Kosai-Fujimoto, Y., Yoshizumi, T., Tomiyama, T., Morinaga, A., Iseda, N., Inokuchi, S., Yugawa, K., Yoshiya, S., Toshima, T., Takeishi, K., Itoh, S., Harada, N., Ikegami, T. & Mori, M., Apr 2020, In : Transplantation Proceedings. 52, 3, p. 889-893 5 p.

Research output: Contribution to journalArticle

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Jan 1 2020, In : FEBS Open Bio. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

N-cadherin mRNA levels in peripheral blood could be a potential indicator of new metastases in breast cancer: A pilot study

Masuda, T., Ueo, H., Kai, Y., Noda, M., Hu, Q., Sato, K., Fujii, A., Hayashi, N., Tsuruda, Y., Otsu, H., Kuroda, Y., Eguchi, H., Ohno, S., Mimori, K. & Ueo, H., Jan 2 2020, In : International journal of molecular sciences. 21, 2, 511.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Phase I dose-escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer

Masuda, T., Noda, M., Kogawa, T., Kitagawa, D., Hayashi, N., Jomori, T., Nakanishi, Y., Nakayama, K. I., Ohno, S. & Mimori, K., Mar 1 2020, In : Cancer Science. 111, 3, p. 924-931 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access

Prognostic Significance of PD-1, PD-L1 and CD8 Gene Expression Levels in Gastric Cancer

Ito, S., Masuda, T., Noda, M., Hu, Q., Shimizu, D., Kuroda, Y., Eguchi, H., Tobo, T., Utsunomiya, T. & Mimori, K., Jan 1 2020, (Accepted/In press) In : Oncology (Switzerland).

Research output: Contribution to journalArticle

Reply

Takeishi, K., Ikegami, T., Yoshizumi, T., Fujimori, N. & Mori, M., May 1 2020, In : Liver Transplantation. 26, 5, p. 727-728 2 p.

Research output: Contribution to journalLetter

Risk factors for the metabolic syndrome components of hypertension, diabetes mellitus, and dyslipidemia after living donor liver transplantation

Toshima, T., Yoshizumi, T., Inokuchi, S., Kosai-Fujimoto, Y., Kurihara, T., Yoshiya, S., Mano, Y., Takeishi, K., Itoh, S., Harada, N., Ikegami, T., Soejima, Y., Shimokawa, M., Maehara, Y. & Mori, M., Apr 2020, In : HPB. 22, 4, p. 511-520 10 p.

Research output: Contribution to journalArticle

SF3B4 plays an oncogenic role in esophageal squamous cell carcinoma

Kidogami, S., Iguchi, T., Sato, K., Yoshikawa, Y., Hu, Q., Nambara, S., Komatsu, H., Ueda, M., Kuroda, Y., Masuda, T., Mori, M., Doki, Y. & Mimori, K., May 2020, In : Anticancer research. 40, 5, p. 2941-2946 6 p.

Research output: Contribution to journalArticle

Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica

Ayano, M., Arinobu, Y., Tsukamoto, H., Ota, S. I., Misaki, K., Nishimura, K., Kimoto, Y., Mitoma, H., Akahoshi, M., Akashi, K., Horiuchi, T. & Niiro, H., Jul 1 2020, In : Rheumatology International. 40, 7, p. 1101-1109 9 p.

Research output: Contribution to journalArticle

The beneficial aspects of spasticity in relation to ambulatory ability in mice with spinal cord injury

Yoshizaki, S., Yokota, K., Kubota, K., Saito, T., Tanaka, M., Konno, D. J., Maeda, T., Matsumoto, Y., Nakashima, Y. & Okada, S., May 1 2020, In : Spinal Cord. 58, 5, p. 537-543 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Usefulness of daily folic acid supplementation during methotrexate treatment of Japanese patients with rheumatoid arthritis

Sasaki, K., Tsuji, T., Kimoto, Y., Yanagihara, Y., Masuguchi, K., Chikamori, A., Watanabe, H., Murakami, T., Oryoji, D., Hashimoto, M., Horiuchi, T. & Egashira, N., Jan 1 2020, (Accepted/In press) In : Modern Rheumatology.

Research output: Contribution to journalArticle

YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

Omori, H., Nishio, M., Masuda, M., Miyachi, Y., Ueda, F., Nakano, T., Sato, K., Mimori, K., Taguchi, K., Hikasa, H., Nishina, H., Tashiro, H., Kiyono, T., Mak, T. W., Nakao, K., Nakagawa, T., Maehama, T. & Suzuki, A., Jan 1 2020, In : Science Advances. 6, 12, eaay3324.

Research output: Contribution to journalArticle

Open Access
2019

Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α

Higuchi, Y., Niidome, T., Miyamoto, Y., Komohara, Y., Tokunou, T., Kubota, T. & Horiuchi, T., Mar 15 2019, In : Heart and Vessels. 34, 3, p. 538-544 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient

Hayashi, N., Kuroda, Y., Saito, T., Tsuruda, Y., Niida, A., Otsu, H., Eguchi, H., Masuda, T., Suzuki, Y., Natsugoe, S. & Mimori, K., Sep 10 2019, In : Surgery today. 49, 9, p. 738-747 10 p.

Research output: Contribution to journalArticle

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida, K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M. & 20 others, Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M. & Ogawa, S., Jan 17 2019, In : Nature. 565, 7739, p. 312-317 6 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG), May 1 2019, In : Journal of Human Genetics. 64, 5, p. 493-498 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ASO Author Reflections: ARL4C and Peritoneal Dissemination in Gastric Cancer

Hu, Q. & Mimori, K., Dec 1 2019, In : Annals of Surgical Oncology. 26, 1 p.

Research output: Contribution to journalComment/debate

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., Aug 30 2019, In : Arthritis Research and Therapy. 21, 1, 198.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2 Citations (Scopus)

CKAP4, a DKK1 receptor, is a biomarker in exosomes derived from pancreatic cancer and a molecular target for therapy

Kimura, H., Yamamoto, H., Harada, T., Fumoto, K., Osugi, Y., Sada, R., Maehara, N., Hikita, H., Mori, S., Eguchi, H., Ikawa, M., Takehara, T. & Kikuchi, A., Jan 1 2019, In : Clinical Cancer Research. 25, 6, p. 1936-1947 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study

Sakai, Y., Kaito, T., Takenaka, S., Yamashita, T., Makino, T., Hosogane, N., Nojiri, K., Suzuki, S., Okada, E., Watanabe, K., Funao, H., Isogai, N., Ueda, S., Hikata, T., Shiono, Y., Watanabe, K., Katsumi, K., Fujiwara, H., Nagamoto, Y., Terai, H. & 47 others, Tamai, K., Matsuoka, Y., Suzuki, H., Nishimura, H., Tagami, A., Yamada, S., Adachi, S., Ohtori, S., Orita, S., Furuya, T., Yoshii, T., Ushio, S., Inoue, G., Miyagi, M., Saito, W., Imagama, S., Ando, K., Sakai, D., Nukaga, T., Kiyasu, K., Kimura, A., Inoue, H., Nakano, A., Harimaya, K., Doi, T., Kawaguchi, K., Yokoyama, N., Oishi, H., Ikegami, S., Futatsugi, T., Shimizu, M., Kakutani, K., Yurube, T., Oshima, M., Uei, H., Aoki, Y., Takahata, M., Iwata, A., Seki, S., Murakami, H., Yoshioka, K., Endo, H., Hongo, M., Nakanishi, K., Abe, T., Tsukanishi, T. & Ishii, K., Nov 2019, In : Journal of Orthopaedic Science. 24, 6, p. 985-990 6 p.

Research output: Contribution to journalArticle

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

Kohsaka, S., Tatsuno, K., Ueno, T., Nagano, M., Shinozaki-Ushiku, A., Ushiku, T., Takai, D., Ikegami, M., Kobayashi, H., Kage, H., Ando, M., Hata, K., Ueda, H., Yamamoto, S., Kojima, S., Oseto, K., Akaike, K., Suehara, Y., Hayashi, T., Saito, T. & 19 others, Takahashi, F., Takahashi, K., Takamochi, K., Suzuki, K., Nagayama, S., Oda, Y., Mimori, K., Ishihara, S., Yatomi, Y., Nagase, T., Nakajima, J., Tanaka, S., Fukayama, M., Oda, K., Nangaku, M., Miyazono, K., Miyagawa, K., Aburatani, H. & Mano, H., Apr 2019, In : Cancer Science. 110, 4, p. 1464-1479 16 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

CRMP5-associated GTPase (CRAG) Is a candidate driver gene for colorectal cancer carcinogenesis

Shimizu, D., Masuda, T., Sato, K., Tsuruda, Y., Otsu, H., Kuroda, Y., Eguchi, H., Kodera, Y. & Mimori, K., Jan 2019, In : Anticancer research. 39, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer

Nakano, M., Kikushige, Y., Miyawaki, K., Kunisaki, Y., Mizuno, S., Takenaka, K., Tamura, S., Okumura, Y., Ito, M., Ariyama, H., Kusaba, H., Nakamura, M., Maeda, T., Baba, E. & Akashi, K., Feb 7 2019, In : Oncogene. 38, 6, p. 780-793 14 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis

Muto, Y., Moroishi, T., Ichihara, K., Nishiyama, M., Shimizu, H., Eguchi, H., Moriya, K., Koike, K., Mimori, K., Mori, M., Katayama, Y. & Nakayama, K. I., Apr 1 2019, In : Journal of Experimental Medicine. 216, 4, p. 950-965 16 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Distinct methylation levels of mature microRNAs in gastrointestinal cancers

Konno, M., Koseki, J., Asai, A., Yamagata, A., Shimamura, T., Motooka, D., Okuzaki, D., Kawamoto, K., Mizushima, T., Eguchi, H., Takiguchi, S., Satoh, T., Mimori, K., Ochiya, T., Doki, Y., Ofusa, K., Mori, M. & Ishii, H., Dec 1 2019, In : Nature communications. 10, 1, 3888.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Epithelial-mesenchymal transition via transforming growth factor beta in pancreatic cancer is potentiated by the inflammatory glycoprotein leucine-rich alpha-2 glycoprotein

Otsuru, T., Kobayashi, S., Wada, H., Takahashi, T., Gotoh, K., Iwagami, Y., Yamada, D., Noda, T., Asaoka, T., Serada, S., Fujimoto, M., Eguchi, H., Mori, M., Doki, Y. & Naka, T., Mar 2019, In : Cancer Science. 110, 3, p. 985-996 12 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Exosomal miR-155 Derived from Hepatocellular Carcinoma Cells Under Hypoxia Promotes Angiogenesis in Endothelial Cells

Matsuura, Y., Wada, H., Eguchi, H., Gotoh, K., Kobayashi, S., Kinoshita, M., Kubo, M., Hayashi, K., Iwagami, Y., Yamada, D., Asaoka, T., Noda, T., Kawamoto, K., Takeda, Y., Tanemura, M., Umeshita, K., Doki, Y. & Mori, M., Mar 15 2019, In : Digestive Diseases and Sciences. 64, 3, p. 792-802 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome

Tsuji, S., Matsuzaki, H., Iseki, M., Nagasu, A., Hirano, H., Ishihara, K., Ueda, N., Honda, Y., Horiuchi, T., Nishikomori, R., Morita, Y. & Mukai, T., Dec 1 2019, In : Clinical and Experimental Immunology. 198, 3, p. 416-429 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese

Kou, I., Otomo, N., Takeda, K., Momozawa, Y., Lu, H. F., Kubo, M., Kamatani, Y., Ogura, Y., Takahashi, Y., Nakajima, M., Minami, S., Uno, K., Kawakami, N., Ito, M., Yonezawa, I., Watanabe, K., Kaito, T., Yanagida, H., Taneichi, H., Harimaya, K. & 27 others, Taniguchi, Y., Shigematsu, H., Iida, T., Demura, S., Sugawara, R., Fujita, N., Yagi, M., Okada, E., Hosogane, N., Kono, K., Nakamura, M., Chiba, K., Kotani, T., Sakuma, T., Akazawa, T., Suzuki, T., Nishida, K., Kakutani, K., Tsuji, T., Sudo, H., Iwata, A., Sato, T., Inami, S., Matsumoto, M., Terao, C., Watanabe, K. & Ikegawa, S., Dec 1 2019, In : Nature communications. 10, 1, 3685.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Hereditary angioedema: Repeated attacks in a 10-year-old boy

Otani, T., Hoshika, S., Horiuchi, T., Hashimura, C. & Sugihara, S., Jan 2019, In : Pediatrics International. 61, 1, p. 101-103 3 p.

Research output: Contribution to journalComment/debate

Hereditary angioedema type 1 with recurrent Dizziness

Ando, T., Torii, R., Kazuta, T., Endo, T., Araki, A., Horiuchi, T., Terao, S. & Katsuno, M., Jan 1 2019, In : Internal Medicine. 58, 13, p. 1961-1963 3 p.

Research output: Contribution to journalArticle

Open Access