Research Output

1999

Dibucaine and tetracaine inhibit the activation of mitogen-activated protein kinase mediated by L-type calcium channels in PC12 cells

Kansha, M., Nagata, T., Irita, K. & Takahashi, S., Dec 1999, In : Anesthesiology. 91, 6, p. 1798-1806 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Differential gene expression of human telomerase-associated protein hTERT and TEP1 in human hematopoietic cells

Uchida, N., Otsuka, T., Shigematsu, H., Maeda, M., Sugio, Y., Itoh, Y. & Niho, Y., Dec 1 1999, In : Leukemia Research. 23, 12, p. 1127-1132 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Establishment and characterization of a Fas-resistant T cell line

Higuchi, M., Horiuchi, T., Sawabe, T., Yoshizawa, S., Nagasawa, K. & Niho, Y., Sep 14 1999, In : Acta Haematologica. 102, 1, p. 22-30 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer

Yamagata, M., Mori, M., Mimori, K., Mafune, K. I., Tanaka, Y., Ueo, H. U. & Akiyoshi, T., 1999, In : British journal of cancer. 79, 3-4, p. 565-569 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Fluid shear stress increases interleukin-11 expression in human osteoblast-like cells: Its role in osteoclast induction

Sakai, K., Mohtai, M., Shida, J. I., Harimaya, K., Benvenuti, S., Brandi, M. L., Kukita, T. & Iwamoto, Y., Jan 1 1999, In : Journal of Bone and Mineral Research. 14, 12, p. 2089-2098 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma

Kondo, M., Yamamoto, H., Nagano, H., Okami, J., Ito, Y., Shimizu, J., Eguchi, H., Miyamoto, A., Dono, K., Umeshita, K., Matsuura, N., Wakasa, K. I., Nakamori, S., Sakon, M. & Monden, M., Dec 1999, In : Clinical Cancer Research. 5, 12, p. 4005-4012 8 p.

Research output: Contribution to journalArticle

169 Citations (Scopus)

Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma

Mafune, K. I., Tanaka, Y., Mimori, K., Mori, M., Takubo, K. & Makuuchi, M., Dec 1999, In : Clinical Cancer Research. 5, 12, p. 4073-4078 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Overlap syndrome of polymyositis and progressive systemic sclerosis associated with interferon therapy for chronic hepatitis C

Otsuka, T., Sakamoto, N., Tanaka, Y., Yamaoka, K., Nakashima, H., Yoshizawa, S., Horiuchi, T. & Niho, Y., 1999, In : Japanese Journal of Rheumatology. 9, 3, p. 259-265 7 p.

Research output: Contribution to journalArticle

Pathogenic Role of Oxidative Stress in Vascular Angiotensin-Converting Enzyme Activation in Long-Term Blockade of Nitric Oxide Synthesis in Rats

Usui, M., Egashira, K., Kitamoto, S., Koyanagi, M., Katoh, M., Kataoka, C., Shimokawa, H. & Takeshita, A., Oct 1999, In : Hypertension. 34, 4, p. 546-551 6 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Remitting seronegative symmetrical synovitis with pitting edema syndrome associated with cryptogenic hepatocellular carcinoma [4]

Nakashima, H., Tanaka, Y., Shigematsu, H., Kanaya, S., Otsuka, T., Hayashida, K., Horiuchi, T. & Niho, Y., Jun 19 1999, In : Clinical and experimental rheumatology. 17, 3, p. 390-391 2 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

Akahoshi, M., Nakashima, H., Tanaka, Y., Kohsaka, T., Nagano, S., Ohgami, E., Arinobu, Y., Yamaoka, K., Niiro, H., Shinozaki, M., Hirakata, H., Horiuchi, T., Otsuka, T. & Niho, Y., Aug 1999, In : Arthritis and rheumatism. 42, 8, p. 1644-1648 5 p.

Research output: Contribution to journalArticle

233 Citations (Scopus)

Up-regulated pyrimidine nucleoside phosphorylase in breast carcinoma correlates with lymph node metastasis

Mimori, K., Ueo, H., Shirasaka, C., Shiraishi, T., Yamagata, M., Haraguchi, M. & Mori, M., Mar 1 1999, In : Annals of Oncology. 10, 1, p. 111-113 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2000

Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of α-interferon and oral tegafur/uracil

Miyamoto, A., Umeshita, K., Sakon, M., Nagano, H., Eguchi, H., Kishimoto, S. I., Dono, K., Nakamori, S., Gotoh, M. & Monden, M., Jan 1 2000, In : Journal of Gastroenterology and Hepatology (Australia). 15, 12, p. 1447-1451 5 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Analysis of Fas ligand gene mutation in patients with systemic lupus erythematosus

Kojima, T., Horiuchi, T., Nishizaka, H., Sawabe, T., Higuchi, M., Harashima, S. I., Yoshizawa, S., Tsukamoto, H., Nagasawa, K. & Niho, Y., Jan 1 2000, In : Arthritis and rheumatism. 43, 1, p. 135-139 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium

Inazuka, M., Tahira, T., Horiuchi, T., Harashima, S., Sawabe, T., Kondo, M., Miyahara, H. & Hayashi, K., Mar 1 2000, In : Rheumatology. 39, 3, p. 262-266 5 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Analysis of the genetic alterations in a case of juvenile multiple colon carcinoma with hypogammaglobulinemia

Mimori, K., Mori, M., Adachi, Y., Antonyak, M. A., Kinoshita, M., Kusaka, H. & Sugimachi, K., 2000, In : Annals of Surgical Oncology. 7, 9, p. 692-695 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A new apoptotic pathway for the complement factor B-derived fragment Bb

Uwai, M., Terui, Y., Mishima, Y., Tomizuka, H., Ikeda, M., Itoh, T., Mori, M., Ueda, M., Inoue, R., Yamada, M., Hayasawa, H., Horiuchi, T., Niho, Y., Matsumoto, M., Ishizaka, Y., Ikeda, K., Ozawa, K. & Hatake, K., 2000, In : Journal of cellular physiology. 185, 2, p. 280-292 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Anticentromere antibody as a risk factor for cancer in patients with systemic sclerosis

Higuchi, M., Horiuchi, T., Ishibashi, N., Yoshizawa, S., Niho, Y. & Nagasawa, K., May 13 2000, In : Clinical Rheumatology. 19, 2, p. 123-126 4 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy inhibits vascular remodeling in rats: Blockade of MCP-1 activity after intramuscular transfer of a mutant gene inhibits vascular remodeling induced by chronic blockade of NO synthesis

Egashira, K., Koyanagi, M., Kitamoto, S., Ni, W., Kataoka, C., Morishita, R., Kaneda, Y., Akiyama, C., Nishida, K. I., Sueishi, K. & Takeshita, A., 2000, In : FASEB Journal. 14, 13, p. 1974-1978 5 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Antioxidants inhibit TNFα-induced motility and invasion of human osteosarcoma cells: Possible involvement of NFκB activation

Harimaya, K., Tanaka, K., Matsumoto, Y., Sato, H., Matsuda, S. & Iwamoto, Y., 2000, In : Clinical and Experimental Metastasis. 18, 2, p. 121-129 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A surgical case of small hepatocellularcarcinoma detected with abdominal lymphnode metastasis

Motoori, M., Nagano, H., Sakon, M., Umeshita, K., Miyamoto, A., Eguchi, H., Kondo, M., Shiozaki, K., Dono, K., Nakamori, S., Nakamura, H., Nakamura, H., Wakasa, K. & Monden, M., 2000, In : Acta Hepatologica Japonica. 41, 11, p. 775-780 6 p.

Research output: Contribution to journalArticle

Behçet's disease associated with complement component 9 (C9) deficiency

Horiuchi, T., Tsukamoto, H., Sawabe, T., Harashima, S., Morita, C., Kashiwagi, Y., Himeji, D., Masumoto, K., Otsuka, T., Kusaba, T. & Nagasawa, K., Jan 12 2000, In : Modern Rheumatology. 10, 4, p. 276-278 3 p.

Research output: Contribution to journalArticle

Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II

Kitamoto, S., Egashira, K., Kataoka, C., Usui, M., Koyanagi, M., Takemoto, M. & Takeshita, A., 2000, In : Journal of hypertension. 18, 12, p. 1795-1800 6 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Clinical significance of hepatic resection in hepatocellular carcinoma: Analysis by disease-free survival curves

Sakon, M., Umeshita, K., Nagano, H., Eguchi, H., Kishimoto, S., Miyamoto, A., Ohshima, S., Dono, K., Nahamori, S., Gotoh, M. & Monden, M., 2000, In : Archives of Surgery. 135, 12, p. 1456-1459 4 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Development of a multiple-marker RT-PCR assay for detection of micrometastases of hepatocellular carcinoma

Miyamoto, A., Fujiwara, Y., Sakon, M., Nagano, H., Sugita, Y., Kondo, M., Eguchi, H., Dono, K., Umeshita, K., Nakamori, S. & Monden, M., Aug 31 2000, In : Digestive Diseases and Sciences. 45, 7, p. 1376-1382 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Dominant expression of a novel splice variant of caspase-8 in human peripheral blood lymphocytes

Horiuchi, T., Himeji, D., Tsukamoto, H., Harashima, S. I., Hashimura, C. & Hayashi, K., Jun 16 2000, In : Biochemical and Biophysical Research Communications. 272, 3, p. 877-881 5 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Down-regulation of human telomeric protein TRF1 gene expression during myeloid differentiation in human hematopoietic cells.

Otsuka, T., Uchida, N., Arima, F., Shigematsu, H., Fukuyama, T., Maeda, M., Sugio, Y., Itoh, Y. & Niho, Y., Jun 2000, In : International journal of hematology. 71, 4, p. 334-339 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Establishment of new multidrug-resistant human osteosarcoma cell lines

Oda, Y., Matsumoto, Y., Harimaya, K., Iwamoto, Y. & Tsuneyoshi, M., 2000, In : Oncology reports. 7, 4, p. 859-866 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Expression of interferon alpha/beta receptor in human hepatocellular carcinoma.

Kondo, M., Nagano, H., Sakon, M., Yamamoto, H., Morimoto, O., Arai, I., Miyamoto, A., Eguchi, H., Dono, K., Nakamori, S., Umeshita, K., Wakasa, K., Ohmoto, Y. & Monden, M., Jul 2000, In : International journal of oncology. 17, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Expression of tissue inhibitor of matrix metalloproteinase-1 in human breast carcinoma

Inoue, H., Mimori, K., Shiraishi, T., Kataoka, A., Sadanaga, N., Ueo, H., Barnard, G. F. & Mori, M., Jul 1 2000, In : Oncology Reports. 7, 4, p. 871-874 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Factors correlated with emotional instability in SLE outpatients

Ishikura, R., Morimoto, N., Tanaka, K., Kinukawa, N., Yoshizawa, S., Horiuchi, T., Nakashima, H. & Otsuka, T., Jan 3 2000, In : Modern Rheumatology. 10, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Important role of local angiotensin II activity mediated via type I receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats

Usui, M., Egashira, K., Tomita, H., Koyanagi, M., Katoh, M., Shimokawa, H., Takeya, M., Yoshimura, T., Matsushima, K. & Takeshita, A., Jan 25 2000, In : Circulation. 101, 3, p. 305-310 6 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)

Increased activity of nuclear factor-κB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats

Kitamoto, S., Egashira, K., Kataoka, C., Koyanagi, M., Katoh, M., Shimokawa, H., Morishita, R., Kaneda, Y., Sueishi, K. & Takeshita, A., 2000, In : Circulation. 102, 7, p. 806-812 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Loss of FHIT expression in transitional cell carcinoma of the urinary bladder

Baffa, R., Gomella, L. G., Vecchione, A., Bassi, P., Mimori, K., Sedor, J., Calviello, C. M., Gardiman, M., Minimo, C., Strup, S. E., McCue, P. A., Kovatich, A. J., Pagano, F., Huebner, K. & Croce, C. M., 2000, In : American Journal of Pathology. 156, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Mannose binding lectin (MBL) gene mutation is not a risk factor for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in Japanese

Horiuchi, T., Tsukamoto, H., Morita, C., Sawabe, T., Harashima, S., Nakashima, H., Miyahara, H., Hashimura, C. & Kondo, M., Oct 2000, In : Genes and Immunity. 1, 7, p. 464-466 3 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

OKT-3-based reconditioning regimen for early graft failure in HLA-non-identical stem cell transplants

Maeda, M., Otsuka, T., Kimura, N., Kozu, T., Fukuyama, T., Uchida, N., Sugio, Y., Itoh, Y., Iino, T., Inaba, S. & Niho, Y., Dec 1 2000, In : British Journal of Haematology. 111, 2, p. 668-673 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Peroxisome proliferator-activated receptor γ activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells

Takeda, K., Ichiki, T., Tokunou, T., Funakoshi, Y., Iino, N., Hirano, K., Kanaide, H. & Takeshita, A., Oct 10 2000, In : Circulation. 102, 15, p. 1834-1839 6 p.

Research output: Contribution to journalArticle

165 Citations (Scopus)

Pravastatin attenuates cardiovascular inflammatory and proliferative changes in a rat model of chronic inhibition of nitric oxide synthesis by its cholesterol-lowering independent actions

Egashira, K., Ni, W. N. I., Inoue, S., Kataoka, C., Kitamoto, S., Koyanagi, M. & Takeshita, A., Jul 2000, In : Hypertension Research. 23, 4, p. 353-358 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Presence of active hepatitis associated with liver cirrhosis is a risk factor for mortality caused by posthepatectomy liver failure

Eguchi, H., Umeshita, K., Sakon, M., Nagano, H., Ito, Y., Kishimoto, S. I., Dono, K., Nakamori, S., Takeda, T., Gotoh, M., Wakasa, K., Matsuura, N. & Monden, M., Aug 31 2000, In : Digestive Diseases and Sciences. 45, 7, p. 1383-1388 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Prognostic impact of tissue inhibitor of matrix metalloproteinase-1 in esophageal carcinoma

Mori, M., Mimori, K., Sadanaga, N., Inoue, H., Tanaka, Y., Mafune, K. I., Ueo, H. & Barnard, G. F., 2000, In : International Journal of Cancer. 88, 4, p. 575-578 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis

Koyanagi, M., Egashira, K., Kitamoto, S., Ni, W., Shimokawa, H., Takeya, M., Yoshimura, T. & Takeshita, A., Oct 31 2000, In : Circulation. 102, 18, p. 2243-2248 6 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Role of Transforming Growth Factor-β1 in Cardiovascular Inflammatory Changes Induced by Chronic Inhibition of Nitric Oxide Synthesis

Koyanagi, M., Egashira, K., Kubo-Inoue, M., Usui, M., Kitamoto, S., Tomita, H., Shimokawa, H. & Takeshita, A., Jan 2000, In : Hypertension. 35, 1, p. 86 1 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Severe thrombocytopenia caused by digitoxin intoxication in a patient with heart failure associated with Sjogren's syndrome

Haro, T., Shimoike, E., Horiuchi, T., Maruyama, T. & Niho, Y., Apr 2000, In : JAPANESE CIRCULATION JOURNAL. 64, 4, p. 309-311 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity

Maeda, T., Haeno, S., Oda, K., Mori, D., Ichinose, H., Nagatsu, T. & Suzuki, T., Sep 2000, In : Brain and Development. 22, SUPPL. 1, p. 50-53 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma

Ito, Y., Monden, M., Takeda, T., Eguchi, H., Umeshita, K., Nagano, H., Nakamori, S., Dono, K., Sakon, M., Nakamura, M., Tsujimoto, M., Nakahara, M., Nakao, K., Yokosaki, Y. & Matsuura, N., 2000, In : British journal of cancer. 82, 6, p. 1211-1217 7 p.

Research output: Contribution to journalArticle

Open Access
70 Citations (Scopus)

Treatment of myxoid liposarcoma in pregnancy

Matsuda, S., Tanaka, K., Harimaya, K., Matsumoto, Y., Sato, H. & Iwamoto, Y., 2000, In : Clinical orthopaedics and related research. 376, p. 195-199 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Vaccination of a refractory essential monoclonal cryoglobulinemia patient with cryoglobulin-pulsed dendritic cells

Maeda, M., Inaba, S., Nomura, A., Tokunaga, Y., Sugio, Y., Itoh, Y., Iino, T., Otsuka, T., Okamura, S. & Niho, Y., 2000, In : Leukemia and Lymphoma. 39, 3-4, p. 441-446 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2001

15-Deoxy-Δ12,14-prostaglandin J2 and Thiazolidinediones Activate the MEK/ERK Pathway through Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells

Takeda, K., Ichiki, T., Tokunou, T., Iino, N. & Takeshita, A., Dec 28 2001, In : Journal of Biological Chemistry. 276, 52, p. 48950-48955 6 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma

Mori, M., Mimori, K., Masuda, T., Yoshinaga, K., Yamashita, K., Matsuyama, A. & Inoue, H., Oct 15 2001, In : Cancer Research. 61, 20, p. 7379-7382 4 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)