Research Output

A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients

Hasegawa, S., Nagano, H., Konno, M., Eguchi, H., Tomokuni, A., Tomimaru, Y., Asaoka, T., Wada, H., Hama, N., Kawamoto, K., Marubashi, S., Nishida, N., Koseki, J., Mori, M., Doki, Y. & Ishii, H., Jan 2016, In : International journal of oncology. 48, 1, p. 145-152 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Activation of protein kinase C induces differentiation in the human T-lymphoblastic cell line MOLT-3

Yamauchi, Y., Nagasawa, K., Mayumi, T., Horiuchi, T. & Niho, Y., Jul 1989, In : British journal of cancer. 60, 1, p. 15-19 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Activin A causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells

Yoshinaga, K., Yamashita, K., Mimori, K., Tanaka, F., Inoue, H. & Mori, M., Jan 1 2008, In : Annals of Surgical Oncology. 15, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Activin A enhances MMP-7 activity via the transcription factor AP-1 in an esophageal squamous cell carcinoma cell line

Yoshinaga, K., Mimori, K., Inoue, H., Kamohara, Y., Yamashita, K., Tanaka, F. & Mori, M., Sep 1 2008, In : International journal of oncology. 33, 3, p. 453-459 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

A curative resection case of intraductal papillary neoplasm of the bile duct followed by one year

Muto, J., Shirabe, K., Mano, Y., Motomura, T., Takeishi, K., Toshima, T., Uchiyama, H., Taketomi, A. & Maehara, Y., 2011, In : Japanese Journal of Gastroenterological Surgery. 44, 8, p. 985-990 6 p.

Research output: Contribution to journalArticle

Acute biliary obstruction due to a large intracholedochal hematoma after living-donor liver transplantation: Report of a case

Nagata, S., Ikegami, T., Takeishi, K., Toshima, T., Sugimachi, K., Gion, T., Soejima, Y., Taketomi, A. & Maehara, Y., May 2010, In : Surgery today. 40, 5, p. 474-476 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans

Kobayakawa, K., Kumamaru, H., Saiwai, H., Kubota, K., Ohkawa, Y., Kishimoto, J., Yokota, K., Ideta, R., Shiba, K., Tozaki-Saitoh, H., Inoue, K., Iwamoto, Y. & Okada, S., Oct 1 2014, In : Science Translational Medicine. 6, 256, 256ra137.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Acute myocardial infarction activates progenitor cells and increases Wnt signalling in the bone marrow

Assmus, B., Iwasaki, M., Schächinger, V., Roexe, T., Koyanagi, M., Iekushi, K., Xu, Q., Tonn, T., Seifried, E., Liebner, S., Kranert, W. T., Grünwald, F., Dimmeler, S. & Zeiher, A. M., Aug 1 2012, In : European heart journal. 33, 15, p. 1911-1919 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Additional acquisition of t(1;21)(p32;q22) in a patient relapsing with acute myelogenous leukemia with NUP98-HOXA9

Aoki, T., Miyamoto, T., Yoshida, S., Yamamoto, A., Yamauchi, T., Yoshimoto, G., Mori, Y., Kamezaki, K., Iwasaki, H., Takenaka, K., Harada, N., Nagafuji, K., Teshima, T. & Akashi, K., Dec 2009, In : International journal of hematology. 88, 5, p. 571-574 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Additional radiotherapy following endoscopic submucosal dissection for T1a-MM/T1b-SM esophageal squamous cell carcinoma improves locoregional control

Hisano, O., Nonoshita, T., Hirata, H., Sasaki, T., Watanabe, H., Wakiyama, H., Ono, M., Ohga, S. & Honda, H., Jan 29 2018, In : Radiation Oncology. 13, 1, 14.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Adenomatous hyperplasia, 4 cm in diameter, including two lesions of well differential hepatocellular carcinoma; a case report

Eguchi, H., Nagano, H., Umeshita, K., Taniguchi, K., Kishimoto, S., Yoshida, K., Dono, K., Nakamori, S., Gotoh, M., Wakasa, K., Sakon, M. & Monden, M., Jan 1 1998, In : Acta Hepatologica Japonica. 39, 8, p. 556-560 5 p.

Research output: Contribution to journalArticle

Adenomyomatous hyperplasia of the common bile duct: Report of a case

Iwaki, K., Shibata, K., Ohta, M., Endo, Y., Uchida, H., Tominaga, M., Okunaga, R., Kai, S. & Kitano, S., Jan 2008, In : Surgery today. 38, 1, p. 85-89 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A diagnosis of a sporadic case of crouzon syndrome with a point mutation in the FGFR-2

Maeda, T., Suzuki, Y., Ogawa, M., Haeno, S., Asada, M., Tanaka, F., Okada, M. & Suzuki, T., 1996, In : Japanese Journal of Human Genetics. 41, 1, 1 p.

Research output: Contribution to journalArticle

A difficult-to-diagnose case of hepatocellular adenoma in a septuagenarian

Murakami, M., Kobayashi, S., Nagano, H., Marubashi, S., Eguchi, H., Takeda, Y., Tanemura, M., Umeshita, K., Kim, T., Wakasa, K., Doki, Y. & Mori, M., 2010, In : Acta Hepatologica Japonica. 51, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Adipose-derived mesenchymal stem cells and regenerative medicine

Konno, M., Hamabe, A., Hasegawa, S., Ogawa, H., Fukusumi, T., Nishikawa, S., Ohta, K., Kano, Y., Ozaki, M., Noguchi, Y., Sakai, D., Kudoh, T., Kawamoto, K., Eguchi, H., Satoh, T., Tanemura, M., Nagano, H., Doki, Y., Mori, M. & Ishii, H., Apr 2013, In : Development Growth and Differentiation. 55, 3, p. 309-318 10 p.

Research output: Contribution to journalReview article

96 Citations (Scopus)

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: Immunological analysis of B cells, T cells and cytokines

Tamimoto, Y., Horiuchi, T., Tsukamoto, H., Otsuka, J., Mitoma, H., Kimoto, Y., Nakashima, H., Muta, K., Abe, Y., Kiyohara, C., Ueda, A., Nagasawa, K., Yoshizawa, S., Shimoda, T. & Harada, M., Jun 2008, In : Rheumatology. 47, 6, p. 821-827 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of α-interferon and oral tegafur/uracil

Miyamoto, A., Umeshita, K., Sakon, M., Nagano, H., Eguchi, H., Kishimoto, S. I., Dono, K., Nakamori, S., Gotoh, M. & Monden, M., Jan 1 2000, In : Journal of Gastroenterology and Hepatology (Australia). 15, 12, p. 1447-1451 5 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Advances in esophageal surgery in elderly patients with thoracic esophageal cancer

Morita, M., Otsu, H., Kawano, H., Kumashiro, R., Taketani, K., Kimura, Y., Saeki, H., Ando, K., Ida, S., Oki, E., Tokunaga, E., Ikeda, T., Kusumoto, T. & Maehara, Y., Apr 2013, In : Anticancer research. 33, 4, p. 1641-1648 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Advantage of autologous blood transfusion in surgery for hepatocellular carcinoma

Tomimaru, Y., Eguchi, H., Marubashi, S., Wada, H., Kobayashi, S., Tanemura, M., Umeshita, K., Doki, Y., Mori, M. & Nagano, H., Aug 28 2011, In : World Journal of Gastroenterology. 17, 32, p. 3709-3715 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Advantage of pancreaticogastrostomy in detecting recurrent intraductal papillary mucinous carcinoma in the remnant pancreas: A case of successful re-resection after pancreaticoduodenectomy

Tomimaru, Y., Ishikawa, O., Ohigashi, H., Eguchi, H., Yamada, T., Sasaki, Y., Miyashiro, I., Ohue, M., Yano, M., Uehara, H., Nakaizumi, A. & Imaoka, S., May 1 2006, In : Journal of Surgical Oncology. 93, 6, p. 511-515 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Adventitial cystic disease of the popliteal vein: Report of a case

Sakamoto, A., Tanaka, K., Matsuda, S., Harimaya, K., Nakamura, T., Oda, Y., Tsuneyoshi, M. & Iwamoto, Y., Dec 2006, In : Surgery today. 36, 12, p. 1098-1100 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis

Horiuchi, T., Kiyohara, C., Tsukamoto, H., Sawabe, T., Furugo, I., Yoshizawa, S., Ueda, A., Tada, Y., Nakamura, T., Kimoto, Y., Mitoma, H., Harashima, S., Yoshizawa, S., Shimoda, T., Okamura, S., Nagasawa, K. & Harada, M., Mar 2007, In : Annals of the Rheumatic Diseases. 66, 3, p. 320-324 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group, Oct 15 2017, In : Human molecular genetics. 26, 20, p. 4086-4092 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A gene-expression signature can quantify the degree of hepatic fibrosis in the rat

Utsunomiya, T., Okamoto, M., Hashimoto, M., Yoshinaga, K., Shiraishi, T., Tanaka, F., Mimori, K., Inoue, H., Watanabe, G., Barnard, G. F. & Mori, M., Sep 1 2004, In : Journal of Hepatology. 41, 3, p. 399-406 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

Okada, Y., Shimane, K., Kochi, Y., Tahira, T., Suzuki, A., Higasa, K., Takahashi, A., Horita, T., Atsumi, T., Ishii, T., Okamoto, A., Fujio, K., Hirakata, M., Amano, H., Kondo, Y., Ito, S., Takada, K., Mimori, A., Saito, K., Kamachi, M. & 24 others, Kawaguchi, Y., Ikari, K., Mohammed, O. W., Matsuda, K., Terao, C., Ohmura, K., Myouzen, K., Hosono, N., Tsunoda, T., Nishimoto, N., Mimori, T., Matsuda, F., Tanaka, Y., Sumida, T., Yamanaka, H., Takasaki, Y., Koike, T., Horiuchi, T., Hayashi, K., Kubo, M., Kamatani, N., Yamada, R., Nakamura, Y. & Yamamoto, K., Jan 2012, In : PLoS genetics. 8, 1, e1002455.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Age-related changes in subtelomeric methylation in the normal Japanese population

Maeda, T., Jing, Z. G., Oyama, J. I., Higuchi, Y. & Makino, N., Apr 2009, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 64, 4, p. 426-434 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
32 Citations (Scopus)

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida, K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M. & 20 others, Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M. & Ogawa, S., Jan 17 2019, In : Nature. 565, 7739, p. 312-317 6 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Aging-associated alteration of subtelomeric methylation in Parkinson's disease

Maeda, T., Guan, J. Z., Oyama, J. I., Higuchi, Y. & Makino, N., Sep 1 2009, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 64, 9, p. 949-955 7 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease

Maeda, T., Guan, J. Z., Koyanagi, M., Higuchi, Y. & Makino, N., Jun 2012, In : Journal of Neurogenetics. 26, 2, p. 245-251 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Aging-related alterations of subtelomeric methylation in sarcoidosis patients

Maeda, T., Jing, Z. G., Higuchi, Y., Oyama, J. I. & Makino, N., Jul 1 2009, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 64, 7, p. 752-760 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A highly accurate inclusive cancer screening test using Caenorhabditis elegans scent detection

Hirotsu, T., Sonoda, H., Uozumi, T., Shinden, Y., Mimori, K., Maehara, Y., Ueda, N. & Hamakawa, M., Mar 11 2015, In : PloS one. 10, 3, e0118699.

Research output: Contribution to journalArticle

26 Citations (Scopus)

A Histone deacetylase inhibitor suppresses epithelial-mesenchymal transition and attenuates chemoresistance in biliary tract cancer

Sakamoto, T., Kobayashi, S., Yamada, D., Nagano, H., Tomokuni, A., Tomimaru, Y., Noda, T., Gotoh, K., Asaoka, T., Wada, H., Kawamoto, K., Marubashi, S., Eguchi, H., Doki, Y. & Mori, M., Jan 4 2016, In : PloS one. 11, 1, e0145985.

Research output: Contribution to journalArticle

29 Citations (Scopus)

A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma

Matsushita, K., Okuda, T., Mori, S., Konno, M., Eguchi, H., Asai, A., Koseki, J., Iwagami, Y., Yamada, D., Akita, H., Asaoka, T., Noda, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Kasahara, Y., Morihiro, K., Satoh, T., Doki, Y., Mori, M. & 2 others, Ishii, H. & Obika, S., 2019, In : ChemMedChem. 14, 15, p. 1384-1391 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Air in the brachiocephalic vein after sternotomy [3]

Hoka, S., Nakayama, T., Nagata, T., Akata, T. & Takahashi, S., Apr 15 1997, In : Journal of Anesthesia. 11, 1, 1 p.

Research output: Contribution to journalLetter

A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases

Mimori, K., Fukagawa, T., Kosaka, Y., Ishikawa, K., Iwatsuki, M., Yokobori, T., Hirasaki, S., Takatsuno, Y., Sakashita, H., Ishii, H., Sasako, M. & Mori, M., Oct 1 2008, In : Annals of Surgical Oncology. 15, 10, p. 2934-2942 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: Molecular mechanisms of carcinogenesis

Toh, Y., Oki, E., Ohgaki, K., Sakamoto, Y., Ito, S., Egashira, A., Saeki, H., Kakeji, Y., Morita, M., Sakaguchi, Y., Okamura, T. & Maehara, Y., Apr 2010, In : International Journal of Clinical Oncology. 15, 2, p. 135-144 10 p.

Research output: Contribution to journalReview article

102 Citations (Scopus)

Allelic Imbalance at an 8q24 Oncogenic SNP is Involved in Activating MYC in Human Colorectal Cancer

Sugimachi, K., Niida, A., Yamamoto, K., Shimamura, T., Imoto, S., Iinuma, H., Shinden, Y., Eguchi, H., Sudo, T., Watanabe, M., Tanaka, J., Kudo, S., Hase, K., Kusunoki, M., Yamada, K., Shimada, Y., Sugihara, K., Maehara, Y., Miyano, S., Mori, M. & 1 others, Mimori, K., 2014, In : Annals of Surgical Oncology. 21, 4, p. 515-521 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

All-in-one ex vivo self-reconstruction technique using an autologous inferior vena cava for a right lobe liver graft with multiple and complex venous orifices

Soejima, Y., Takeishi, K., Ikegami, T., Uchiyama, H., Taketomi, A. & Maehara, Y., Jul 2010, In : Liver Transplantation. 16, 7, p. 909-913 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A long noncoding RNA, lncRNA-ATB, is involved in the progression and prognosis of colorectal cancer

Iguchi, T., Uchi, R., Nambara, S., Saito, T., Komatsu, H., Hirata, H., Ueda, M., Sakimura, S., Takano, Y., Kurashige, J., Shinden, Y., Eguchi, H., Sugimachi, K., Maehara, Y. & Mimori, K., Mar 1 2015, In : Anticancer research. 35, 3, p. 1385-1388 4 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

A Long Non-coding RNA Activated by Transforming Growth Factor-β is an Independent Prognostic Marker of Gastric Cancer

Saito, T., Kurashige, J., Nambara, S., Komatsu, H., Hirata, H., Ueda, M., Sakimura, S., Uchi, R., Takano, Y., Shinden, Y., Iguchi, T., Eguchi, H., Ehata, S., Murakami, K., Sugimachi, K. & Mimori, K., Dec 1 2015, In : Annals of Surgical Oncology. 22, p. 915-922 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

A long-term survival case of advanced sigmoid colon cancer with massive metastases to the para-aortic lymph nodes

Ogino, T., Ohue, M., Noura, S., Seki, Y., Goto, K., Motoori, M., Kishi, K., Eguchi, H., Yamada, T., Miyashiro, I., Tomita, H., Ohigashi, H., Yano, M., Ishikawa, O. & Imaoka, S., Nov 2007, In : Gan to kagaku ryoho. Cancer & chemotherapy. 34, 12, p. 2056-2058 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A long-term survival case of hepatocellular carcinoma with bone metastasis and inferior vena cava tumor thrombus successfully treated with multidisciplinary therapy

Yamada, D., Wada, H., Kobayashi, S., Marubashi, S., Eguchi, H., Takeda, Y., Tanemura, M., Umeshita, K., Doki, Y., Mori, M. & Nagano, H., Nov 2010, In : Japanese Journal of Cancer and Chemotherapy. 37, 12, p. 2670-2672 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A long-term survival case of hepatocellular carcinoma with lymph node metastasis on the posterior surface of the pancreas head and portal vein tumor thrombus successfully treated with hepatopancreatoduodenectomy and adjuvant interferon-α and 5-fluorouracil combination therapy

Tomimaru, Y., Kobayashi, S., Nagano, H., Murakami, M., Wada, H., Marubashi, S., Eguchi, H., Takeda, Y., Tanemura, M., Umeshita, K., Wakasa, K., Doki, Y. & Mori, M., Nov 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 12, p. 2389-2391 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A long-term survival case of hepatocellular carcinoma with portal vein and inferior vena cava tumor thrombi

Hashimoto, V., Wada, H., Kobayashi, S., Marubashi, S., Eguchi, H., Takeda, Y., Tanemura, M., Umeshita, K., Doki, Y., Mori, M. & Nagano, H., Nov 2010, In : Japanese Journal of Cancer and Chemotherapy. 37, 12, p. 2693-2695 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A long-term survival case of pancreatic cancer with hepatic metastasis after pancreaticoduodenectomy successfully treated by S-1 and gemcitabine combination chemotherapy

Hoshino, H., Takeda, Y., Nagano, H., Nakamori, S., Kobayashi, S., Eguchi, H., Marubashi, S., Tanemura, M., Kitagawa, T., Umeshita, K., Monden, M., Doki, Y. & Mori, M., Nov 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 12, p. 2419-2421 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Alteration of Telomere Length and Subtelomeric Methylation in Human Endothelial Cell Under Different Levels of Hypoxia

Guan, J. Z., Guan, W. P., Maeda, T. & Makino, N., Jan 2012, In : Archives of Medical Research. 43, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
6 Citations (Scopus)

Altered expression of genes associated with telomere maintenance and cell function of human vascular endothelial cell at elevated temperature

Maeda, T., Guan, J. Z., Koyanagi, M. & Makino, N., Oct 29 2014, In : Molecular and cellular biochemistry. 397, 1-2, p. 305-312 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma

Sugimachi, K., Nishio, M., Aishima, S., Kuroda, Y., Iguchi, T., Komatsu, H., Hirata, H., Sakimura, S., Eguchi, H., Bekki, Y., Takenaka, K., Maehara, Y., Suzuki, A. & Mimori, K., Jul 1 2017, In : Oncology (Switzerland). 93, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)