Research Output

2002

Role of dihydropyrimidine dehydrogenase activity in patients with esophageal cancer

Saeki, H., Ito, S., Futatsugi, M., Kimura, Y., Ohga, T. & Sugimachi, K., Nov 2002, In : Anticancer research. 22, 6 B, p. 3789-3792 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies

Kikuchi, Y., Koarada, S., Tada, Y., Ushiyama, O., Morito, F., Suzuki, N., Ohta, A., Miyake, K., Kimoto, M., Horiuchi, T. & Nagasawa, K., Dec 1 2002, In : Arthritis and rheumatism. 46, 12, p. 3259-3265 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Solitary lymphangioma of the femur. A case report

Sakamoto, A., Matsuda, S., Tanaka, K., Shukuri, T., Harimaya, K. & Iwamoto, Y., 2002, In : Journal of Orthopaedic Science. 7, 4, p. 501-504 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Therapy-related chronic myelogenous leukaemia following autologous stem cell transplantation for Ewing's sarcoma

Numata, A., Shimoda, K., Gondo, H., Kato, K., Aoki, K., Ito, Y., Takase, K., Asano, Y., Okamura, T., Niho, Y. & Harada, M., 2002, In : British Journal of Haematology. 117, 3, p. 613-616 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Traumatic neuroma of the anterior cervical nerve root with no subjective episode of trauma. Report of four cases

Nomura, H., Harimaya, K., Orii, H., Shiba, K., Ueta, T. & Iwaki, T., Oct 1 2002, In : Journal of Neurosurgery. 97, 3 SUPPL., p. 393-396 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Tumor cell apoptosis by irradiation-induced nitric oxide production in vascular endothelium

Hirakawa, M., Oike, M., Masuda, K. & Ito, Y., Mar 1 2002, In : Cancer Research. 62, 5, p. 1450-1457 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Vascular compression caused by solitary osteochondroma: Useful diagnostic methods of magnetic resonance angiography and Doppler ultrasonography

Sakamoto, A., Tanaka, K., Matsuda, S., Harimaya, K. & Iwamoto, Y., 2002, In : Journal of Orthopaedic Science. 7, 4, p. 439-443 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2001

15-Deoxy-Δ12,14-prostaglandin J2 and Thiazolidinediones Activate the MEK/ERK Pathway through Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells

Takeda, K., Ichiki, T., Tokunou, T., Iino, N. & Takeshita, A., Dec 28 2001, In : Journal of Biological Chemistry. 276, 52, p. 48950-48955 6 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma

Mori, M., Mimori, K., Masuda, T., Yoshinaga, K., Yamashita, K., Matsuyama, A. & Inoue, H., Oct 15 2001, In : Cancer Research. 61, 20, p. 7379-7382 4 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

A case of Beḩet's disease with chronic and repeated sudden hearing loss: Successful treatment with intravenous cyclophosphamide pulse therapy

Hagiwara, N., Harashima, S., Tukamoto, H. & Horiuchi, T., 2001, In : Ryumachi. 41, 5, p. 858-863 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Angiogenesis related factors: angiopoietin-2

Masuda, T., Etoh, T., Mori, M. & Tanaka, S., Jan 1 2001, In : Nippon rinsho. Japanese journal of clinical medicine. 59 Suppl 6, p. 151-156 6 p.

Research output: Contribution to journalReview article

A novel technique for surgical resection of spinal meningioma

Saito, T., Arizono, T., Maeda, T., Terada, K. & Iwamoto, Y., Aug 15 2001, In : Spine. 26, 16, p. 1805-1808 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis

Ni, W., Egashira, K., Kataoka, C., Kitamoto, S., Koyanagi, M., Inoue, S. & Takeshita, A., Aug 31 2001, In : Circulation research. 89, 5, p. 415-421 7 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese molecular and functional analysis

Morita, C., Horiuchi, T., Tsukamoto, H., Hatta, N., Kikuchi, Y., Arinobu, Y., Otsuka, T., Sawabe, T., Harashima, S. I., Nagasawa, K. & Niho, Y., 2001, In : Arthritis and rheumatism. 44, 12, p. 2819-2827 9 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells

Tokunou, T., Ichiki, T., Takeda, K., Funakoshi, Y., Iino, N. & Takeshita, A., 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 11, p. 1764-1769 6 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Clinical application of quantitative analysis for detection of hematogenous spread of hepatocellular carcinoma by real-time PCR.

Miyamoto, A., Nagano, H., Sakon, M., Fujiwara, Y., Sugita, Y., Eguchi, H., Kondo, M., Arai, I., Morimoto, O., Dono, K., Umeshita, K., Nakamori, S. & Monden, M., Mar 2001, In : International journal of oncology. 18, 3, p. 527-532 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Clinical significance of MT1-MMP mRNA expression in breast cancer

Mimori, K., 2001, In : Oncology reports. 8, 2, p. 401-403 3 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Critical role of rho-kinase and MEK/EFK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression

Takeda, K., Ichiki, T., Tokunou, T., Iino, N., Fujii, S., Kitabatake, A., Shimokawa, H. & Takeshita, A., May 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 5, p. 868-873 6 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Defect of lck in a patient with common variable immunodeficiency.

Sawabe, T., Horiuchi, T., Nakamura, M., Tsukamoto, H., Nakahara, K., Harashima, S. I., Tsuchiya, T. & Nakano, S., Jun 2001, In : International journal of molecular medicine. 7, 6, p. 609-614 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Difference in B cell activation between dermatomyositis and polymyositis: Analysis of the expression of RP105 on peripheral blood B cells

Kikuchi, Y., Koarada, S., Tada, Y., Ushiyam, O., Morito, F., Suzuki, N., Ohta, A., Horiuchi, T., Miyake, K. & Nagasawa, K., 2001, In : Annals of the Rheumatic Diseases. 60, 12, p. 1137-1140 4 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in vascular smooth muscle cells

Ichiki, T., Takeda, K., Tokunou, T., Iino, N., Egashira, K., Shimokawa, H., Hirano, K., Kanaide, H. & Takeshita, A., 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 12, p. 1896-1901 6 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells

Ishii, H., Dumon, K. R., Vecchione, A., Trapasso, F., Mimori, K., Alder, H., Mori, M., Sozzi, G., Baffa, R., Huebner, K. & Croce, C. M., Feb 15 2001, In : Cancer Research. 61, 4, p. 1578-1584 7 p.

Research output: Contribution to journalArticle

110 Citations (Scopus)

Expression and prognostic significance of O6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers

Matsukura, S., Miyazaki, K., Yakushiji, H., Ogawa, A., Harimaya, K., Nakabeppu, Y. & Sekiguchi, M., 2001, In : Annals of Surgical Oncology. 8, 10, p. 807-816 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Factors associated with anxiety, depression and suicide ideation in female outpatients with SLE in Japan

Ishikura, R., Morimoto, N., Tanaka, K., Kinukawa, N., Yoshizawa, S., Horiuchi, T., Nakashima, H. & Otsuka, T., 2001, In : Clinical Rheumatology. 20, 6, p. 394-400 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Hepatic arterial infusion chemotherapy combined with interferon-alpha for hepatocellular carcinoma

Nagano, H., Eguchi, H., Sakon, M. & Monden, M., Oct 2001, In : Nippon rinsho. Japanese journal of clinical medicine. 59 Suppl 6, p. 748-752 5 p.

Research output: Contribution to journalReview article

Intracellular cytokine profile of CD14 positive cells in patients with hematologic malignancies and solid tumors during hematologic recovery phase after intensive chemotherapy designed to mobilize peripheral blood stem cells

Maeda, M., Tokunaga, Y., Nomura, A., Inaba, S., Sugio, Y., Itoh, Y., Iino, T., Otsuka, T. & Niho, Y., 2001, In : Biomedicine and Pharmacotherapy. 55, 2, p. 96-101 6 p.

Research output: Contribution to journalArticle

Loss of chemokine SDF-1α-mediated CXCR4 signalling and receptor internalization in human hepatoma cell line HepG2

Mitra, P., De, A., Ethier, M. F., Mimori, K., Kodys, K., Shibuta, K., Mori, M., Madison, J. M., Miller-Graziano, C. & Barnard, G. F., May 1 2001, In : Cellular Signalling. 13, 5, p. 311-319 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Mutation of DNASE1 in people with systemic lupus erythematosus

Yasutomo, K., Horiuchi, T., Kagami, S., Tsukamoto, H., Hashimura, C., Urushihara, M. & Kuroda, Y., 2001, In : Nature genetics. 28, 4, p. 313-314 2 p.

Research output: Contribution to journalArticle

413 Citations (Scopus)

New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout mice

Ni, W., Egashira, K., Kitamoto, S., Kataoka, C., Koyanagi, M., Inoue, S., Imaizumi, K., Akiyama, C., Nishida, K. I. & Takeshita, A., Apr 24 2001, In : Circulation. 103, 16, p. 2096-2101 6 p.

Research output: Contribution to journalArticle

209 Citations (Scopus)

Outside-to-inside signal through the membrane, TNF-α induces E-selectin (CD62E) expression on activated human CD4+ T cells

Harashima, S. I., Horiuchi, T., Hatta, N., Morita, C., Higuchi, M., Sawabe, T., Tsukamoto, H., Tahira, T., Hayashi, K., Fujita, S. & Niho, Y., Jan 1 2001, In : Journal of Immunology. 166, 1, p. 130-136 7 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Propofol inhibits FMLP-stimulated phosphorylation of p42 mitogen-activated protein kinase and chemotaxis in human neutrophils

Nagata, T., Kansha, M., Irita, K. & Takahashi, S., 2001, In : British Journal of Anaesthesia. 86, 6, p. 853-858 6 p.

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)

Reactive oxygen species-mediated homologous downregulation of angiotensin II type I receptor mRNA by angiotensin II

Ichiki, T., Takeda, K., Tokunou, T., Funakoshi, Y., Ito, K., Iino, N. & Takeshita, A., 2001, In : Hypertension. 37, 2 II, p. 535-540 6 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Regression by ACE inhibition of arteriosclerotic changes induced by chronic blockade of NO synthesis in rats

Katoh, M., Egashira, K., Kataoka, C., Usui, M., Koyanagi, M., Kitamoto, S., Ohmachi, Y., Takeshita, A. & Narita, H., May 2001, In : American Journal of Physiology - Heart and Circulatory Physiology. 280, 5 49-5, p. H2306-H2312

Research output: Contribution to journalArticle

19 Citations (Scopus)

Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

Shiraishi, T., Druck, T., Mimori, K., Flomenberg, J., Berk, L., Alder, H., Miller, W., Huebner, K. & Croce, C. M., May 8 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 10, p. 5722-5727 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
51 Citations (Scopus)

The clinical significance of detecting small numbers of carcinoma

Mimori, K., Masuda, T., Kataoka, A. & Mori, M., Jan 1 2001, In : Gan to kagaku ryoho. Cancer & chemotherapy. 28, 6, p. 756-761 6 p.

Research output: Contribution to journalArticle

Thrombin induces interleukin-6 expression through the cAMP response element in vascular smooth muscle cells

Tokunou, T., Ichiki, T., Takeda, K., Funakoshi, Y., Iino, N., Shimokawa, H., Egashira, K. & Takeshita, A., 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 11, p. 1759-1763 5 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2000

Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of α-interferon and oral tegafur/uracil

Miyamoto, A., Umeshita, K., Sakon, M., Nagano, H., Eguchi, H., Kishimoto, S. I., Dono, K., Nakamori, S., Gotoh, M. & Monden, M., Jan 1 2000, In : Journal of Gastroenterology and Hepatology (Australia). 15, 12, p. 1447-1451 5 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Analysis of Fas ligand gene mutation in patients with systemic lupus erythematosus

Kojima, T., Horiuchi, T., Nishizaka, H., Sawabe, T., Higuchi, M., Harashima, S. I., Yoshizawa, S., Tsukamoto, H., Nagasawa, K. & Niho, Y., Jan 1 2000, In : Arthritis and rheumatism. 43, 1, p. 135-139 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium

Inazuka, M., Tahira, T., Horiuchi, T., Harashima, S., Sawabe, T., Kondo, M., Miyahara, H. & Hayashi, K., Mar 1 2000, In : Rheumatology. 39, 3, p. 262-266 5 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Analysis of the genetic alterations in a case of juvenile multiple colon carcinoma with hypogammaglobulinemia

Mimori, K., Mori, M., Adachi, Y., Antonyak, M. A., Kinoshita, M., Kusaka, H. & Sugimachi, K., 2000, In : Annals of Surgical Oncology. 7, 9, p. 692-695 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A new apoptotic pathway for the complement factor B-derived fragment Bb

Uwai, M., Terui, Y., Mishima, Y., Tomizuka, H., Ikeda, M., Itoh, T., Mori, M., Ueda, M., Inoue, R., Yamada, M., Hayasawa, H., Horiuchi, T., Niho, Y., Matsumoto, M., Ishizaka, Y., Ikeda, K., Ozawa, K. & Hatake, K., 2000, In : Journal of cellular physiology. 185, 2, p. 280-292 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Anticentromere antibody as a risk factor for cancer in patients with systemic sclerosis

Higuchi, M., Horiuchi, T., Ishibashi, N., Yoshizawa, S., Niho, Y. & Nagasawa, K., May 13 2000, In : Clinical Rheumatology. 19, 2, p. 123-126 4 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy inhibits vascular remodeling in rats: Blockade of MCP-1 activity after intramuscular transfer of a mutant gene inhibits vascular remodeling induced by chronic blockade of NO synthesis

Egashira, K., Koyanagi, M., Kitamoto, S., Ni, W., Kataoka, C., Morishita, R., Kaneda, Y., Akiyama, C., Nishida, K. I., Sueishi, K. & Takeshita, A., 2000, In : FASEB Journal. 14, 13, p. 1974-1978 5 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Antioxidants inhibit TNFα-induced motility and invasion of human osteosarcoma cells: Possible involvement of NFκB activation

Harimaya, K., Tanaka, K., Matsumoto, Y., Sato, H., Matsuda, S. & Iwamoto, Y., 2000, In : Clinical and Experimental Metastasis. 18, 2, p. 121-129 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A surgical case of small hepatocellularcarcinoma detected with abdominal lymphnode metastasis

Motoori, M., Nagano, H., Sakon, M., Umeshita, K., Miyamoto, A., Eguchi, H., Kondo, M., Shiozaki, K., Dono, K., Nakamori, S., Nakamura, H., Nakamura, H., Wakasa, K. & Monden, M., 2000, In : Acta Hepatologica Japonica. 41, 11, p. 775-780 6 p.

Research output: Contribution to journalArticle

Behçet's disease associated with complement component 9 (C9) deficiency

Horiuchi, T., Tsukamoto, H., Sawabe, T., Harashima, S., Morita, C., Kashiwagi, Y., Himeji, D., Masumoto, K., Otsuka, T., Kusaba, T. & Nagasawa, K., Jan 12 2000, In : Modern Rheumatology. 10, 4, p. 276-278 3 p.

Research output: Contribution to journalArticle

Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II

Kitamoto, S., Egashira, K., Kataoka, C., Usui, M., Koyanagi, M., Takemoto, M. & Takeshita, A., 2000, In : Journal of hypertension. 18, 12, p. 1795-1800 6 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Clinical significance of hepatic resection in hepatocellular carcinoma: Analysis by disease-free survival curves

Sakon, M., Umeshita, K., Nagano, H., Eguchi, H., Kishimoto, S., Miyamoto, A., Ohshima, S., Dono, K., Nahamori, S., Gotoh, M. & Monden, M., 2000, In : Archives of Surgery. 135, 12, p. 1456-1459 4 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Development of a multiple-marker RT-PCR assay for detection of micrometastases of hepatocellular carcinoma

Miyamoto, A., Fujiwara, Y., Sakon, M., Nagano, H., Sugita, Y., Kondo, M., Eguchi, H., Dono, K., Umeshita, K., Nakamori, S. & Monden, M., Aug 31 2000, In : Digestive Diseases and Sciences. 45, 7, p. 1376-1382 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)