Center for Cellular and Molecular Medicine

Research Output

2000

Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells

Maeda, T., Kowatari, M., Kosugi, H. & Saito, H., Dec 1 2000, In : Blood. 96, 12, p. 3847-56 10 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)
2001

Histone acetylation induced by granulocyte colony-stimulating factor in a map kinase-dependent manner

Miyata, Y., Towatari, M., Maeda, T., Ozawa, Y. & Saito, H., May 11 2001, In : Biochemical and Biophysical Research Communications. 283, 3, p. 655-60 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Ozawa, Y., Towatari, M., Tsuzuki, S., Hayakawa, F., Maeda, T., Miyata, Y., Tanimoto, M. & Saito, H., Oct 1 2001, In : Blood. 98, 7, p. 2116-23 8 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2003
4 Citations (Scopus)

Salazosulfapyridine induced hypersensitivity syndrome associated with reactivation of humanherpes virus 6

Kunisaki, Y., Goto, H., Kitagawa, K. & Nagano, M., Feb 1 2003, In : Internal Medicine. 42, 2, p. 203-207 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2004

Differential requirements for DOCK2 and phosphoinositide-3-kinase γ during T and B lymphocyte homing

Nombela-Arrieta, C., Lacalle, R. A., Montoya, M. C., Kunisaki, Y., Megías, D., Marqués, M., Carrera, A. C., Mañes, S., Fukui, Y., Martínez-A, C. & Stein, J. V., Sep 1 2004, In : Immunity. 21, 3, p. 429-441 13 p.

Research output: Contribution to journalArticle

188 Citations (Scopus)
2005

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

Jiang, H., Pan, F., Erickson, L. M., Jang, M. S., Sanui, T., Kunisaki, Y., Sasazuki, T., Kobayashi, M. & Fukui, Y., Oct 17 2005, In : Journal of Experimental Medicine. 202, 8, p. 1121-1130 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells

Warner, J. K., Wang, J. C. Y., Takenaka, K., Doulatov, S., McKenzie, J. L., Harrington, L. & Dick, J. E., Oct 2005, In : Leukemia. 19, 10, p. 1794-1805 12 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)
2006

Acute lymphoblastic leukemia presenting with calcineurin-inhibitor induced pain syndrome after a second allogeneic bone marrow transplantation

Takashima, S., Numata, A., Miyamoto, T., Shirakawa, T., Kinoshita, R., Kato, K., Takenaka, K., Harada, N., Nagafuji, K., Taniguchi, S. & Harada, M., Oct 2006, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 47, 10, p. 1372-1376 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Kunisaki, Y., Nishikimi, A., Tanaka, Y., Takii, R., Noda, M., Inayoshi, A., Watanabe, K. I., Sanematsu, F., Sasazuki, T., Sasaki, T. & Fukui, Y., Aug 28 2006, In : Journal of Cell Biology. 174, 5, p. 647-652 6 p.

Research output: Contribution to journalArticle

145 Citations (Scopus)

DOCK2 is required in T cell precursors for development of Vα14 NK T cells

Kunisaki, Y., Tanaka, Y., Sanui, T., Inayoshi, A., Noda, M., Nakayama, T., Harada, M., Taniguchi, M., Sasazuki, T. & Fukui, Y., Apr 15 2006, In : Journal of Immunology. 176, 8, p. 4640-4645 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Hematopoietic stem cell transplantation for natural killer-cell lineage neoplasms

Suzuki, R., Suzumiya, J., Nakamura, S., Kagami, Y., Kameoka, J. I., Sakai, C., Mukai, H., Takenaka, K., Yoshino, T., Tsuzuki, T., Sugimori, H., Kawa, K., Kodera, Y. & Oshimi, K., Feb 1 2006, In : Bone Marrow Transplantation. 37, 4, p. 425-431 7 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Primary hepatic lymphoma 1 year after resection of hepatocellular carcinoma

Nonami, A., Takenaka, K., Harada, N., Kono, K., Kamezaki, K., Numata, A., Karube, K., Miyamoto, T., Nagafuji, K., Ohshima, K. & Harada, M., Dec 20 2006, In : Journal of Clinical Oncology. 24, 36, p. 5784-5786 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Success with infliximab in treating refractory hemophagocytic lymphohistiocytosis

Henzan, T., Nagafuji, K., Tsukamoto, H., Miyamoto, T., Gondo, H., Imashuku, S. & Harada, M., Jan 1 2006, In : American Journal of Hematology. 81, 1, p. 59-61 3 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
2007

Collection of mobilized peripheral blood stem cells from a donor with severe iron deficient anemia

Kamezaki, K., Miyamoto, T., Henzan, T., Numata, A., Iwasaki, H., Nagafuji, K., Harada, M., Teshima, T. & Akashi, K., Nov 1 2007, In : Journal of Clinical Apheresis. 22, 5, p. 292-294 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Distinctive expression of myelomonocytic markers and down-regulation of CD34 in acute myelogenous leukaemia with FLT3 tandem duplication and nucleophosmin mutation

Mori, Y., Yoshimoto, G., Kumano, T., Miyamoto, T., Iino, T., Takenaka, K., Iwasaki, H., Harada, N., Kinukawa, N., Nagafuji, K., Teshima, T., Shimoda, K., Akashi, K. & Harada, M., Jul 1 2007, In : European Journal of Haematology. 79, 1, p. 17-24 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population

McKenzie, J. L., Takenaka, K., Gan, O. I., Doedens, M. & Dick, J. E., Jan 15 2007, In : Blood. 109, 2, p. 543-545 3 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Marked improvement of cardiac function early after non-myeloablative BMT in a heavily transfused patient with severe aplastic anemia and heart failure [1]

Kunisaki, Y., Takase, K., Miyamoto, T., Fukata, M., Nonami, A., Kamezaki, K., Kaji, Y., Gondo, H., Harada, M. & Nagafuji, K., Sep 1 2007, In : Bone Marrow Transplantation. 40, 6, p. 593-595 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis

Nagafuji, K., Nonami, A., Kumano, T., Kikushige, Y., Yoshimoto, G., Takenaka, K., Shimoda, K., Ohga, S., Yasukawa, M., Horiuchi, H., Ishii, E. & Harada, M., Jul 1 2007, In : Haematologica. 92, 7, p. 978-981 4 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells

Takenaka, K., Prasolava, T. K., Wang, J. C. Y., Mortin-Toth, S. M., Khalouei, S., Gan, O. I., Dick, J. E. & Danska, J. S., Dec 1 2007, In : Nature Immunology. 8, 12, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

296 Citations (Scopus)

Rituximab does not compromise the mobilization and engraftment of autologous peripheral blood stem cells in diffuse-large B-cell lymphoma

Kamezaki, K., Kikushige, Y., Numata, A., Miyamoto, T., Takase, K., Henzan, H., Aoki, K., Kato, K., Nonami, A., Kamimura, T., Arima, F., Takenaka, K., Harada, N., Fukuda, T., Hayashi, S., Ohno, Y., Eto, T., Harada, M. & Nagafuji, K., May 1 2007, In : Bone Marrow Transplantation. 39, 9, p. 523-527 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Successful treatment of myelodysplastic syndrome (MDS)-related intestinal Behçet's disease by up-front cord blood transplantation

Nonami, A., Takenaka, K., Sumida, C., Aizawa, K., Kamezaki, K., Miyamoto, T., Harada, N., Nagafuji, K., Teshima, T. & Harada, M., Oct 15 2007, In : Internal Medicine. 46, 20, p. 1753-1756 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Successful treatment of primary cardiac lymphoma by rituximab-CHOP and high-dose chemotherapy with autologous peripheral blood stem cell transplantation

Nonami, A., Takenaka, K., Kamezaki, K., Miyamoto, T., Harada, N., Nagafuji, K., Teshima, T. & Harada, M., Apr 1 2007, In : International journal of hematology. 85, 3, p. 264-266 3 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Successful treatment of primary plasma cell leukaemia by allogeneic stem cell transplantation from haploidentical sibling

Nonami, A., Miyamoto, T., Kuroiwa, M., Kunisaki, Y., Kamezaki, K., Takenaka, K., Harada, N., Teshima, T., Harada, M. & Nagafuji, K., Dec 1 2007, In : Japanese journal of clinical oncology. 37, 12, p. 969-972 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2

Tanaka, Y., Hamano, S., Gotoh, K., Murata, Y., Kunisaki, Y., Nishikimi, A., Takii, R., Kawaguchi, M., Inayoshi, A., Masuko, S., Himeno, K., Sasazuki, T. & Fukui, Y., Oct 1 2007, In : Nature Immunology. 8, 10, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Toxoplasmosis encephalitis following severe graft-vs.-host disease after allogeneic hematopoietic stem cell transplantation: 17 Yr experience in Fukuoka BMT group

Matsuo, Y., Takeishi, S., Miyamoto, T., Nonami, A., Kikushige, Y., Kunisaki, Y., Kamezaki, K., Tu, L., Hisaeda, H., Takenaka, K., Harada, N., Kamimura, T., Ohno, Y., Eto, T., Teshima, T., Gondo, H., Harada, M. & Nagafuji, K., Oct 1 2007, In : European Journal of Haematology. 79, 4, p. 317-321 5 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Tyk2 mutation homologous to V617F Jak2 is not found in essential thrombocythaemia, although it induces constitutive signaling and growth factor independence

Shide, K., Shimoda, K., Kamezaki, K., Kakumitsu, H., Kumano, T., Numata, A., Ishikawa, F., Takenaka, K., Yamamoto, K., Matsuda, T. & Harada, M., Aug 1 2007, In : Leukemia Research. 31, 8, p. 1085-1092 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tyk2 mutation homologous to V617F Jak2 is not found in essential thrombocythaemia, although it induces constitutive signaling and growth factor independence

Shide, K., Shimoda, K., Kamezaki, K., Kakumitsu, H., Kumano, T., Numata, A., Ishikawa, F., Takenaka, K., Yamamoto, K., Matsuda, T. & Harada, M., Aug 2007, In : Leukemia Research. 31, 8, p. 1077-1084 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2008

Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F

Shide, K., Shimoda, H. K., Kumano, T., Karube, K., Kameda, T., Takenaka, K., Oku, S., Abe, H., Katayose, K. S., Kubuki, Y., Kusumoto, K., Hasuike, S., Tahara, Y., Nagata, K., Matsuda, T., Ohshima, K., Harada, M. & Shimoda, K., Jan 1 2008, In : Leukemia. 22, 1, p. 87-95 9 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival

Kikushige, Y., Yoshimoto, G., Miyamoto, T., Iino, T., Mori, Y., Iwasaki, H., Niiro, H., Takenaka, K., Nagafuji, K., Harada, M., Ishikawa, F. & Akashi, K., Jan 1 2008, In : Journal of Immunology. 180, 11, p. 7358-7367 10 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Successful treatment of parainfluenza virus 3 pneumonia with oral ribavirin and methylprednisolone in a bone marrow transplant recipient

Shima, T., Yoshimoto, G., Nonami, A., Yoshida, S., Kamezaki, K., Iwasaki, H., Takenaka, K., Miyamoto, T., Harada, N., Teshima, T., Akashi, K. & Nagafuji, K., Oct 1 2008, In : International journal of hematology. 88, 3, p. 336-340 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2009

A case of secondary pulmonary alveolar proteinosis associated with myelodysplastic syndrome, complicated with disseminated M. abscessus infection

Asai, Y., Ouchi, H., Ohosima, T., Nakano, R., Yamano, Y., Inoshima, I., Yamauchi, T., Fukuyama, S., Inoue, H. & Nakanishi, Y., Dec 2009, In : Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 47, 12, p. 1120-1125 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Additional acquisition of t(1;21)(p32;q22) in a patient relapsing with acute myelogenous leukemia with NUP98-HOXA9

Aoki, T., Miyamoto, T., Yoshida, S., Yamamoto, A., Yamauchi, T., Yoshimoto, G., Mori, Y., Kamezaki, K., Iwasaki, H., Takenaka, K., Harada, N., Nagafuji, K., Teshima, T. & Akashi, K., Dec 1 2009, In : International journal of hematology. 88, 5, p. 571-574 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Disseminated tuberculosis following second unrelated cord blood transplantation for acute myelogenous leukemia

Shima, T., Yoshimoto, G., Miyamoto, T., Yoshida, S., Kamezaki, K., Takenaka, K., Iwasaki, H., Harada, N., Nagafuji, K., Teshima, T., Shimono, N. & Akashi, K., Feb 1 2009, In : Transplant Infectious Disease. 11, 1, p. 75-77 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Efficacy and feasibility of IDEA therapy for refractory or relapsed non-Hodgkin's lymphoma

Nishimori, H., Fujii, N., Maeda, Y., Matsuoka, K. I., Takenaka, K., Shinagawa, K., Ikeda, K., Matsuo, K., Harada, M. & Tanimoto, M., May 2009, In : Anticancer research. 29, 5, p. 1749-1754 6 p.

Research output: Contribution to journalArticle

Encephalomyelitis mimicking multiple sclerosis associated with chronic graft-versus-host disease after allogeneic bone marrow transplantation

Matsuo, Y., Kamezaki, K., Takeishi, S., Takenaka, K., Eto, T., Nonami, A., Miyamoto, T., Iwasaki, H., Harada, N., Nagafuji, K., Teshima, T. & Akashi, K., Oct 5 2009, In : Internal Medicine. 48, 16, p. 1453-1456 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation

Yoshimoto, G., Miyamoto, T., Jabbarzadeh-Tabrizi, S., Iino, T., Rocnik, J. L., Kikushige, Y., Mori, Y., Shima, T., Iwasaki, H., Takenaka, K., Nagafuji, K., Mizuno, S. I., Niiro, H., Gilliland, G. D. & Akashi, K., Dec 3 2009, In : Blood. 114, 24, p. 5034-5043 10 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Identification of the human eosinophil lineage-committed progenitor: Revision of phenotypic definition of the human common myeloid progenitor

Mori, Y., Iwasaki, H., Kohno, K., Yoshimoto, G., Kikushige, Y., Okeda, A., Uike, N., Niiro, H., Takenaka, K., Nagafuji, K., Miyamoto, T., Harada, M., Takatsu, K. & Akashi, K., Jan 16 2009, In : Journal of Experimental Medicine. 206, 1, p. 183-193 11 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Infectious complications in patients receiving autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases

Kohno, K., Nagafuji, K., Tsukamoto, H., Horiuchi, T., Takase, K., Aoki, K., Henzan, H., Kamezaki, K., Takenaka, K., Miyamoto, T., Teshima, T., Harada, M. & Akashi, K., Aug 1 2009, In : Transplant Infectious Disease. 11, 4, p. 318-323 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Oral valganciclovir as preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients

Takenaka, K., Eto, T., Nagafuji, K., Kamezaki, K., Matsuo, Y., Yoshimoto, G., Harada, N., Yoshida, M., Henzan, H., Takase, K., Miyamoto, T., Akashi, K., Harada, M. & Teshima, T., Mar 1 2009, In : International journal of hematology. 89, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Rituximab for the treatment of corticosteroid-refractory chronic graft-versus-host disease

Teshima, T., Nagafuji, K., Henzan, H., Miyamura, K., Takase, K., Hidaka, M., Miyamoto, T., Takenaka, K., Akashi, K. & Harada, M., Sep 1 2009, In : International journal of hematology. 90, 2, p. 253-260 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Second unrelated cord blood transplantation using a reduced-intensity conditioning regimen combined with gemtuzumab ozogamicin in patients with relapsed acute myelogenous leukemia

Yamauchi, T., Mori, Y., Miyamoto, T., Kamezaki, K., Aoki, T., Yamamoto, A., Takenaka, K., Iwasaki, H., Harada, N., Nagafuji, K., Teshima, T. & Akashi, K., Oct 1 2009, In : International journal of hematology. 90, 3, p. 416-420 5 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The impact of cytogenetic abnormalities on the prognosis of primary myelofibrosis: A prospective survey of 202 cases in Japan

Hidaka, T., Shide, K., Shimoda, H., Kameda, T., Toyama, K., Katayose, K., Kubuki, Y., Nagata, K., Takenaka, K., Akashi, K., Okamura, T., Niho, Y., Mizoguchi, H., Omine, M., Ozawa, K., Harada, M. & Shimoda, K., Oct 1 2009, In : European Journal of Haematology. 83, 4, p. 328-333 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2010

Clinical profiles of 7 patients with chronic myelogenous leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia treated with dasatinib

Hoshino, T., Tahara, K., Miyawaki, K., Hatsumi, N., Takada, S., Miyawaki, S. & Sakura, T., Jan 1 2010, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 51, 3, p. 181-188 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cord blood stem cell transplantation in a patient with disseminated mucormycosis and acute myelogenous leukemia

Aoki, T., Kamezaki, K., Miyamoto, T., Nagafuji, K., Mori, Y., Yamauchi, T., Takenaka, K., Iwasaki, H., Harada, N., Shimono, N., Teshima, T. & Akashi, K., Jun 2010, In : Transplant Infectious Disease. 12, 3, p. 277-279 3 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

High incidence of false-positive Aspergillus galactomannan test in multiple myeloma

Mori, Y., Nagasaki, Y., Kamezaki, K., Takenaka, K., Iwasaki, H., Harada, N., Miyamoto, T., Abe, Y., Shimono, N., Akashi, K. & Teshima, T., Jun 1 2010, In : American Journal of Hematology. 85, 6, p. 449-451 3 p.

Research output: Contribution to journalLetter

24 Citations (Scopus)

High Incidence of Human Herpes Virus 6-Associated Encephalitis/Myelitis following a Second Unrelated Cord Blood Transplantation

Mori, Y., Miyamoto, T., Nagafuji, K., Kamezaki, K., Yamamoto, A., Saito, N., Kato, K., Takenaka, K., Iwasaki, H., Harada, N., Abe, Y., Teshima, T. & Akashi, K., Nov 1 2010, In : Biology of Blood and Marrow Transplantation. 16, 11, p. 1596-1602 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

JAK2 V617F uses distinct signalling pathways to induce cell proliferation and neutrophil activation: Research paper

Oku, S., Takenaka, K., Kuriyama, T., Shide, K., Kumano, T., Kikushige, Y., Urata, S., Yamauchi, T., Iwamoto, C., Shimoda, H. K., Miyamoto, T., Nagafuji, K., Kishimoto, J., Shimoda, K. & Akashi, K., Aug 1 2010, In : British Journal of Haematology. 150, 3, p. 334-344 11 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Long-term outcomes of autologous PBSCT for peripheral T-cell lymphoma: Retrospective analysis of the experience of the Fukuoka BMT group

Numata, A., Miyamoto, T., Ohno, Y., Kamimura, T., Kamezaki, K., Tanimoto, T., Takase, K., Henzan, H., Kato, K., Takenaka, K., Fukuda, T., Harada, N., Nagafuji, K., Teshima, T., Akashi, K., Harada, M. & Eto, T., Feb 1 2010, In : Bone Marrow Transplantation. 45, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)