Research Output 1987 2019

2019

Dairy consumption and risk of functional disability in an elderly Japanese population: The Hisayama Study

Yoshida, D., Ohara, T., Hata, J., Shibata, M., Hirakawa, Y., Honda, T., Uchida, K., Takasugi, S., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 1 2019, In : American Journal of Clinical Nutrition. 109, 6, p. 1664-1671 8 p.

Research output: Contribution to journalArticle

Activities of Daily Living
Population
Independent Living
Geriatrics
Mental Competency
Exercise
Population
Independent Living
Japan
Light
Open Access
Diabetes Mellitus
Insulin Resistance
Population
Homeostasis
Energy Intake
1 Citation (Scopus)

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study

Ohara, T., Hata, J., Tanaka, M., Honda, T., Yamakage, H., Yoshida, D., Inoue, T., Hirakawa, Y., Kusakabe, T., Shibata, M., Teraoka, T., Kitazono, T., Kanba, S., Satoh-Asahara, N. & Ninomiya, T., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dementia
Biomarkers
Alzheimer Disease
Vascular Dementia
2018
3 Citations (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
Myeloid Cells
Insulin Resistance
Serum
Population
Fats
2 Citations (Scopus)
Dementia
Sleep
Mortality
Hypnotics and Sedatives
Confidence Intervals
2 Citations (Scopus)
Eicosapentaenoic Acid
Arachidonic Acid
Depression
Serum
Population
2 Citations (Scopus)

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population

Iida, M., Ikeda, F., Hata, J., Hirakawa, Y., Ohara, T., Mukai, N., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., May 1 2018, In : Gastric Cancer. 21, 3, p. 383-390 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Population
Pepsinogen A
Proportional Hazards Models
Helicobacter pylori
Cardiovascular Diseases
Decision Support Techniques
Coronary Disease
Stroke
Blood Pressure
2 Citations (Scopus)

Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar1

Kiyohara, T., Miyano, K., Kamakura, S., Hayase, J., Chishiki, K., Kohda, A. & Sumimoto, H., Jun 1 2018, In : Genes to Cells. 23, 6, p. 480-493 14 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
NADPH Oxidase
Qa-SNARE Proteins
Superoxides
Endoplasmic Reticulum
1 Citation (Scopus)

Impact of age at menarche on obesity and glycemic control in Japanese patients with type 2 diabetes: Fukuoka Diabetes Registry

Sumi, A., Iwase, M., Nakamura, U., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Komorita, Y., Yoshinari, M. & Kitazono, T., Sep 1 2018, In : Journal of Diabetes Investigation. 9, 5, p. 1216-1223 8 p.

Research output: Contribution to journalArticle

Menarche
Type 2 Diabetes Mellitus
Registries
Obesity
Body Mass Index
4 Citations (Scopus)

Impact of body weight loss from maximum weight on fragility bone fractures in Japanese patients with type 2 diabetes: The fukuoka diabetes registry

Komorita, Y., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Sumi, A., Yoshinari, M., Nakamura, U., Kang, D. & Kitazono, T., May 1 2018, In : Diabetes care. 41, 5, p. 1061-1067 7 p.

Research output: Contribution to journalArticle

Bone Fractures
Type 2 Diabetes Mellitus
Registries
Weight Loss
Body Weight
2 Citations (Scopus)

Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men: A cross-sectional study in work-site group

Morinaga, Y., Matsumura, K., Kansui, Y., Sakata, S., Goto, K., Haga, Y., Oishi, E., Seki, T., Ohtsubo, T. & Kitazono, T., Jan 2 2018, In : Clinical and Experimental Hypertension. 40, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Workplace
Cross-Sectional Studies
Blood Pressure
Hypertension
1 Citation (Scopus)

Impact of obstructive sleep apnea on long-term blood pressure variability in Japanese men: a cross-sectional study of a work-site population

Kansui, Y., Matsumura, K., Morinaga, Y., Inoue, M., Sakata, S., Oishi, E., Goto, K., Ohtsubo, T., Ooboshi, H. & Kitazono, T., Jan 1 2018, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Workplace
Cross-Sectional Studies
Blood Pressure
Population
3 Citations (Scopus)

Incidence of diabetic foot ulcer in Japanese patients with type 2 diabetes mellitus: The Fukuoka diabetes registry

Iwase, M., Fujii, H., Nakamura, U., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Sumi, A., Komorita, Y., Yoshinari, M. & Kitazono, T., Mar 1 2018, In : Diabetes Research and Clinical Practice. 137, p. 183-189 7 p.

Research output: Contribution to journalArticle

Diabetic Foot
Type 2 Diabetes Mellitus
Registries
Incidence
Amputation
3 Citations (Scopus)
Exercise
Population
Independent Living
Body Mass Index
Age Groups
1 Citation (Scopus)

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study

Furuta, Y., Hata, J., Mukai, N., Hirakawa, Y., Ago, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 1 2018, In : Atherosclerosis. 273, p. 84-90 7 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Japan
Incidence
Stroke
Blood Pressure
3 Citations (Scopus)

The serum creatinine to cystatin C ratio predicts bone fracture in patients with type 2 diabetes: The Fukuoka Diabetes Registry

Komorita, Y., Iwase, M., Fujii, H., Ide, H., Ohkuma, T., Jodai-Kitamura, T., Sumi, A., Yoshinari, M., Nakamura, U. & Kitazono, T., Dec 1 2018, In : Diabetes Research and Clinical Practice. 146, p. 202-210 9 p.

Research output: Contribution to journalArticle

Cystatin C
Bone Fractures
Type 2 Diabetes Mellitus
Registries
Creatinine
2017
4 Citations (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
10 Citations (Scopus)

Angiotensin II receptor-neprilysin inhibitor sacubitril/valsartan improves endothelial dysfunction in spontaneously hypertensive rats

Seki, T., Goto, K., Kansui, Y., Ohtsubo, T., Matsumura, K. & Kitazono, T., Oct 1 2017, In : Journal of the American Heart Association. 6, 10, e006617.

Research output: Contribution to journalArticle

Valsartan
Neprilysin
Angiotensin Receptors
Inbred SHR Rats
Endothelium
5 Citations (Scopus)
Vitamin D
Cause of Death
Respiratory Tract Infections
Cardiovascular Infections
Serum
5 Citations (Scopus)

Blood pressure control status and relationship between salt intake and lifestyle including diet in hypertensive outpatients treated at a general hospital

Ohta, Y., Kimura, Y., Kitaoka, C., Sakata, S., Abe, I. & Kawano, Y., Jan 2 2017, In : Clinical and Experimental Hypertension. 39, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

General Hospitals
Life Style
Outpatients
Salts
Diet
1 Citation (Scopus)

Circulating ferritin concentrations are differentially associated with serum adipokine concentrations in Japanese men and premenopausal women

Kimura, Y., Yasuda, K., Kurotani, K., Akter, S., Kashino, I., Hayabuchi, H., Sato, M. & Mizoue, T., Dec 1 2017, In : European Journal of Nutrition. 56, 8, p. 2497-2505 9 p.

Research output: Contribution to journalArticle

Adipokines
Ferritins
Nicotinamide Phosphoribosyltransferase
Leptin
Serum
16 Citations (Scopus)

Day-to-Day Blood Pressure Variability and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study

Oishi, E., Ohara, T., Sakata, S., Fukuhara, M., Hata, J., Yoshida, D., Shibata, M., Ohtsubo, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Aug 8 2017, In : Circulation. 136, 6, p. 516-525 10 p.

Research output: Contribution to journalArticle

Dementia
Blood Pressure
Vascular Dementia
Population
Alzheimer Disease
2 Citations (Scopus)

Dietary Protein Intake and Stroke Risk in a General Japanese Population: The Hisayama Study

Ozawa, M., Yoshida, D., Hata, J., Ohara, T., Mukai, N., Shibata, M., Uchida, K., Nagata, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 1 2017, In : Stroke. 48, 6, p. 1478-1486 9 p.

Research output: Contribution to journalArticle

Dietary Proteins
Stroke
Population
Cerebral Hemorrhage
Vegetable Proteins
4 Citations (Scopus)

Disruption of xanthine oxidoreductase gene attenuates renal ischemia reperfusion injury in mice

Haga, Y., Ohtsubo, T., Murakami, N., Noguchi, H., Kansui, Y., Goto, K., Matsumura, K. & Kitazono, T., Aug 1 2017, In : Life Sciences. 182, p. 73-79 7 p.

Research output: Contribution to journalArticle

Xanthine Dehydrogenase
Reperfusion Injury
Genes
Kidney
Reperfusion
15 Citations (Scopus)

Downregulation of Endothelial Transient Receptor Potential Vanilloid Type 4 Channel and Small-Conductance of Ca 2+ -Activated K + Channels Underpins Impaired Endothelium-Dependent Hyperpolarization in Hypertension

Seki, T., Goto, K., Kiyohara, K., Kansui, Y., Murakami, N., Haga, Y., Ohtsubo, T., Matsumura, K. & Kitazono, T., Jan 1 2017, In : Hypertension. 69, 1, p. 143-153 11 p.

Research output: Contribution to journalArticle

TRPV Cation Channels
Endothelium
Down-Regulation
Arteries
Hypertension

Epidemiology of diabetes and cardiovascular disease

Mukai, N. & Ninomiya, T., Jan 1 2017, In : Journal of the Japan Diabetes Society. 60, 7, p. 472-474 3 p.

Research output: Contribution to journalArticle

Epidemiology
Cardiovascular Diseases
13 Citations (Scopus)

Inhibition of aryl hydrocarbon receptor signaling and induction of NRF2-mediated antioxidant activity by cinnamaldehyde in human keratinocytes

Hiroshi, U., Yasumatsu, M., Morino-Koga, S., Mitoma, C. & Furue, M., Jan 1 2017, In : Journal of Dermatological Science. 85, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Keratinocytes
Antioxidants
Chemical activation
Dioxins

Joint impact of modifiable lifestyle behaviors on glycemic control and insulin resistance in patients with type 2 diabetes: the Fukuoka Diabetes Registry

Ohkuma, T., Iwase, M., Fujii, H., Ide, H., Kaizu, S., Jodai, T., Kikuchi, Y., Idewaki, Y., Sumi, A., Nakamura, U. & Kitazono, T., Aug 1 2017, In : Diabetology International. 8, 3, p. 296-305 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Registries
Insulin Resistance
Life Style
Joints

Morning and evening blood pressures are associated with intima-media thickness in a general population: The hisayama study

Sakata, S., Hata, J., Fukuhara, M., Yonemoto, K., Mukai, N., Yoshida, D., Kishimoto, H., Ohtsubo, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2017, In : Circulation Journal. 81, 11, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

Blood Pressure
Population
Hypertension
Carotid Intima-Media Thickness
Carotid Artery Diseases
3 Citations (Scopus)

Serum adiponectin predicts fracture risk in individuals with type 2 diabetes: the Fukuoka Diabetes Registry

Komorita, Y., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Sumi, A., Yoshinari, M., Nakamura, U., Kang, D. & Kitazono, T., Oct 1 2017, In : Diabetologia. 60, 10, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Adiponectin
Type 2 Diabetes Mellitus
Registries
Serum
5 Citations (Scopus)
Chronic Renal Insufficiency
Cardiovascular Diseases
Coronary Disease
Serum
Confidence Intervals
1 Citation (Scopus)

The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

Sumi, A., Nakamura, U., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Komorita, Y., Yoshinari, M., Hirakawa, Y., Hirano, A., Kubo, M. & Kitazono, T., Dec 12 2017, In : BMC Medical Genetics. 18, 1, 146.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Type 2 Diabetes Mellitus
Registries
Insulin
1 Citation (Scopus)

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: The Hisayama Study

Nagata, M., Hata, J., Hirakawa, Y., Mukai, N., Yoshida, D., Ohara, T., Kishimoto, H., Kawano, H., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2017, In : Journal of epidemiology. 27, 12, p. 578-583 6 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Arachidonic Acid
Serum
Neoplasms
Independent Living
29 Citations (Scopus)

Trends in dementia prevalence, incidence, and survival rate in a Japanese community

Ohara, T., Hata, J., Yoshida, D., Mukai, N., Nagata, M., Iwaki, T., Kitazono, T., Kanba, S., Kiyohara, Y. & Ninomiya, T., May 16 2017, In : Neurology. 88, 20, p. 1925-1932 8 p.

Research output: Contribution to journalArticle

Dementia
Survival Rate
Alzheimer Disease
Incidence
Vascular Dementia
10 Citations (Scopus)

Ubiquitylation of Ku80 by RNF126 promotes completion of nonhomologous end joining-mediated DNA repair

Ishida, N., Nakagawa, T., Iemura, S. I., Yasui, A., Shima, H., Katoh, Y., Nagasawa, Y., Natsume, T., Igarashi, K. & Nakayama, K., Jan 1 2017, In : Molecular and Cellular Biology. 37, 4, e00347.

Research output: Contribution to journalArticle

DNA End-Joining Repair
Ubiquitination
DNA Repair
Double-Stranded DNA Breaks
DNA
2 Citations (Scopus)

White-coat and masked hypertension are associated with albuminuria in a general population: The Hisayama Study

Hata, J., Fukuhara, M., Sakata, S., Arima, H., Hirakawa, Y., Yonemoto, K., Mukai, N., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Nov 1 2017, In : Hypertension Research. 40, 11, p. 937-943 7 p.

Research output: Contribution to journalArticle

Masked Hypertension
White Coat Hypertension
Albuminuria
Hypertension
Population
2016
18 Citations (Scopus)

Association between diabetes and hippocampal atrophy in Elderly Japanese: The Hisayama study

Hirabayashi, N., Hata, J., Ohara, T., Mukai, N., Nagata, M., Shibata, M., Gotoh, S., Furuta, Y., Yamashita, F., Yoshihara, K., Kitazono, T., Sudo, N., Kiyohara, Y. & Ninomiya, T., Sep 1 2016, In : Diabetes care. 39, 9, p. 1543-1549 7 p.

Research output: Contribution to journalArticle

Atrophy
Brain
Glucose
Magnetic Resonance Imaging
Independent Living
15 Citations (Scopus)

Combination of helicobacter pylori antibody and serum pepsinogen as a good predictive tool of gastric cancer incidence: 20-year prospective data from the hisayama study

Ikeda, F., Shikata, K., Hata, J., Fukuhara, M., Hirakawa, Y., Ohara, T., Mukai, N., Nagata, M., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2016, In : Journal of epidemiology. 26, 12, p. 629-636 8 p.

Research output: Contribution to journalArticle

Pepsinogen A
Helicobacter pylori
Stomach Neoplasms
Antibodies
Incidence

Diabetes and cancer risk: evidence from epidemiological studies

Mukai, N. & Kiyohara, Y., Apr 1 2016, In : Nihon rinsho. Japanese journal of clinical medicine. 74, p. 401-404 4 p.

Research output: Contribution to journalArticle

Diabetes Complications
Glucose Tolerance Test
Epidemiologic Studies
Diabetes Mellitus
Neoplasms
11 Citations (Scopus)

Effects of smoking and its cessation on creatinine- and cystatin C-based estimated glomerular filtration rates and albuminuria in male patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry

Ohkuma, T., Nakamura, U., Iwase, M., Ide, H., Fujii, H., Jodai, T., Kaizu, S., Kikuchi, Y., Idewaki, Y., Sumi, A., Hirakawa, Y. & Kitazono, T., Oct 1 2016, In : Hypertension Research. 39, 10, p. 744-751 8 p.

Research output: Contribution to journalArticle

Cystatin C
Albuminuria
Smoking Cessation
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
2 Citations (Scopus)

Family dysfunction A comparison of chronic widespread pain and chronic localized pain

Hayaki, C., Anno, K., Shibata, M., Iwaki, R., Kawata, H., Sudo, N. & Hosoi, M., Jan 1 2016, In : Medicine (United States). 95, 49, p. e5495

Research output: Contribution to journalArticle

Chronic Pain
Pain
Odds Ratio
Psychology
Demography
2 Citations (Scopus)

Orthostatic hypotension predicts a poor prognosis in elderly people with dementia

Oishi, E., Sakata, S., Tsuchihashi, T., Tominaga, M. & Fujii, K., Jan 1 2016, In : Internal Medicine. 55, 15, p. 1947-1952 6 p.

Research output: Contribution to journalArticle

Orthostatic Hypotension
Dementia
Blood Pressure
Demography
Frail Elderly
1 Citation (Scopus)
Sleep
Parenting
Mothers
Confidence Intervals
Parents
4 Citations (Scopus)

Salt intake, home blood pressure, and perinatal outcome in pregnant women

Inoue, M., Tsuchihashi, T., Hasuo, Y., Ogawa, M., Tominaga, M., Arakawa, K., Oishi, E., Sakata, S., Ohtsubo, T., Matsumura, K. & Kitazono, T., Jan 1 2016, In : Circulation Journal. 80, 10, p. 2165-2172 8 p.

Research output: Contribution to journalArticle

Pregnancy Induced Hypertension
Pregnant Women
Salts
Blood Pressure
Urine
4 Citations (Scopus)

Salt intake and eating habits of school-aged children

Ohta, Y., Iwayama, K., Suzuki, H., Sakata, S., Hayashi, S., Iwashima, Y., Takata, A. & Kawano, Y., Nov 1 2016, In : Hypertension Research. 39, 11, p. 812-817 6 p.

Research output: Contribution to journalArticle

Feeding Behavior
Salts
Parents
Pupil
Life Style
10 Citations (Scopus)

Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community

Hata, J., Mukai, N., Nagata, M., Ohara, T., Yoshida, D., Kishimoto, H., Shibata, M., Hirakawa, Y., Endo, M., Ago, T., Kitazono, T., Oike, Y., Kiyohara, Y. & Ninomiya, T., Aug 1 2016, In : Arteriosclerosis, thrombosis, and vascular biology. 36, 8, p. 1686-1691 6 p.

Research output: Contribution to journalArticle

Angiopoietins
Cardiovascular Diseases
Serum
Proteins
Confidence Intervals
19 Citations (Scopus)

Serum uric acid as a risk factor for chronic kidney disease in a Japanese community-the hisayama study

Takae, K., Nagata, M., Hata, J., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Tsuruya, K., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2016, In : Circulation Journal. 80, 8, p. 1857-1862 6 p.

Research output: Contribution to journalArticle

Uric Acid
Chronic Renal Insufficiency
Albuminuria
Serum
Kidney