Clinical Chemistry and Laboratory Medicine

Research Output 2007 2019

Filter
Article
2019
3 Citations (Scopus)

Development and validation of the 22-item Tarumi's Modern-Type Depression Trait Scale: Avoidance of Social Roles, Complaint, and Low Self-Esteem (TACS-22)

Kato, T. A., Katsuki, R., Kubo, H., Shimokawa, N., Sato-Kasai, M., Hayakawa, K., Kuwano, N., Umene-Nakano, W., Tateno, M., Setoyama, D., Kang, D., Watabe, M., Sakamoto, S., Teo, A. R. & Kanba, S., Jan 1 2019, In : Psychiatry and clinical neurosciences. 73, 8, p. 448-457 10 p.

Research output: Contribution to journalArticle

Open Access
Self Concept
Depression
Personality
Psychometrics
Japan
2 Citations (Scopus)

Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure

Maekawa, S., Takada, S., Nambu, H., Furihata, T., Kakutani, N., Setoyama, D., Ueyanagi, Y., Kang, D., Sabe, H. & Kinugawa, S., Oct 16 2019, In : Cell Communication and Signaling. 17, 1, 128.

Research output: Contribution to journalArticle

Open Access
Oxidative Phosphorylation
Linoleic Acid
Heart Failure
Cardiolipins
Cardiac Myocytes
6 Citations (Scopus)

Suicide and microglia: Recent findings and future perspectives based on human studies

Suzuki, H., Ohgidani, M., Kuwano, N., Chrétien, F., Lorin de la Grandmaison, G., Onaya, M., Tominaga, I., Setoyama, D., Kang, D., Mimura, M., Kanba, S. & Kato, T. A., Jan 29 2019, In : Frontiers in Cellular Neuroscience. 13, p. 1-10 10 p., 31.

Research output: Contribution to journalArticle

Open Access
Microglia
Suicide
Psychiatry
Kynurenine
Suicidal Ideation
2018
7 Citations (Scopus)

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

Matsuda, S., Yasukawa, T., Sakaguchi, Y., Ichiyanagi, K., Unoki, M., Gotou, K., Fukuda, K., Sasaki, H., Suzuki, T. & Kang, D., 2018, In : Scientific Reports. 8, 1

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Analysis of spatiotemporal metabolomic dynamics for sensitively monitoring biological alterations in cisplatin-induced acute kidney injury

Irie, M., Hayakawa, E., Fujimura, Y., Honda, Y., Setoyama, D., Wariishi, H., Hyodo, F. & Miura, D., Jan 29 2018, In : Biochemical and Biophysical Research Communications. 496, 1, p. 140-146 7 p.

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Metabolomics
Environmental Monitoring
Acute Kidney Injury
Cisplatin
2 Citations (Scopus)

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

Gotoh, K., Morisaki, T., Setoyama, D., Sasaki, K., Yagi, M., Igami, K., Mizuguchi, S., Uchiumi, T., Fukui, Y. & Kang, D., Nov 13 2018, In : Cell Reports. 25, 7, p. 1800-1815.e4

Research output: Contribution to journalArticle

Metabolism
Dendritic Cells
Pyruvic Acid
Citric Acid
Oxidoreductases
11 Citations (Scopus)

Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: An exploratory pilot case-control study

Kuwano, N., Kato, T. A., Setoyama, D., Sato-Kasai, M., Shimokawa, N., Hayakawa, K., Ohgidani, M., Sagata, N., Kubo, H., Kishimoto, J., Kang, D. & Kanba, S., Apr 15 2018, In : Journal of Affective Disorders. 231, p. 74-82 9 p.

Research output: Contribution to journalArticle

Kynurenine
Major Depressive Disorder
Tryptophan
Case-Control Studies
Biomarkers
2017
6 Citations (Scopus)

Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses

Saito, T., Uchiumi, T., Yagi, M., Amamoto, R., Setoyama, D., Matsushima, Y. & Kang, D., Aug 1 2017, In : Cardiovascular research. 113, 10, p. 1173-1185 13 p.

Research output: Contribution to journalArticle

Takotsubo Cardiomyopathy
Cardiac Myocytes
Mitochondria
Mitochondrial Proteins
Sirolimus
10 Citations (Scopus)
Endoplasmic Reticulum Stress
Neoplastic Stem Cells
Doxycycline
Stem Cells
Apoptosis
1 Citation (Scopus)

Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: A pilot study

Sagata, N., Kato, T. A., Kano, S. I., Ohgidani, M., Shimokawa, N., Sato-Kasai, M., Hayakawa, K., Kuwano, N., Wilson, A. M., Ishizuka, K., Kato, S., Nakahara, T., Nakahara-Kido, M., Setoyama, D., Sakai, Y., Ohga, S., Furue, M., Sawa, A. & Kanba, S., Dec 1 2017, In : Scientific reports. 7, 1, 13905.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Gene Expression
Messenger RNA
Phenotype
Induced Pluripotent Stem Cells
2 Citations (Scopus)
Leukoencephalopathies
Oligodendroglia
Axons
Electron Transport
Central Nervous System
4 Citations (Scopus)

p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

Sasaki, K., Gotoh, K., Miake, S., Setoyama, D., Yagi, M., Igami, K., Uchiumi, T. & Kang, D., Jun 2017, In : EBioMedicine. 20, p. 161-172 12 p.

Research output: Contribution to journalArticle

Endotoxins
Lipopolysaccharides
Shock
Interleukin-6
Fibroblasts
18 Citations (Scopus)

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1

Tajiri, H., Uruno, T., Shirai, T., Takaya, D., Matsunaga, S., Setoyama, D., Watanabe, M., Kukimoto-Niino, M., Oisaki, K., Ushijima, M., Sanematsu, F., Honma, T., Terada, T., Oki, E., Shirasawa, S., Maehara, Y., Kang, D., Côté, J. F., Yokoyama, S., Kanai, M. & 1 others, Fukui, Y., May 2 2017, In : Cell Reports. 19, 5, p. 969-980 12 p.

Research output: Contribution to journalArticle

Nutrients
Cell Survival
Cells
Pyridones
Guanine Nucleotide Exchange Factors
2016
32 Citations (Scopus)

Plasma metabolites predict severity of depression and suicidal ideation in psychiatric patients-a multicenter pilot analysis

Setoyama, D., Kato, T. A., Hashimoto, R., Kunugi, H., Hattori, K., Hayakawa, K., Sato-Kasai, M., Shimokawa, N., Kaneko, S., Yoshida, S., Goto, Y. I., Yasuda, Y., Yamamori, H., Ohgidani, M., Sagata, N., Miura, D., Kang, D. & Kanba, S., Dec 2016, In : PloS one. 11, 12, e0165267.

Research output: Contribution to journalArticle

Suicidal Ideation
Metabolites
Psychiatry
Depression
metabolites
2 Citations (Scopus)

Serum depletion induced cancer stem cell-like phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells

Monji, K., Uchiumi, T., Hoshizawa, S., Yagi, M., Matsumoto, T., Setoyama, D., Matsushima, Y., Gotoh, K., Amamoto, R. & Kang, D., Jan 1 2016, In : Oncotarget. 7, 46, p. 75221-75234 14 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Oxygen Consumption
Nitric Oxide
Phenotype
Serum
2015
32 Citations (Scopus)

Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration

Wang, L., Ishihara, T., Ibayashi, Y., Tatsushima, K., Setoyama, D., Hanada, Y., Takeichi, Y., Sakamoto, S., Yokota, S., Mihara, K., Kang, D., Ishihara, N., Takayanagi, R. & Nomura, M., Oct 24 2015, In : Diabetologia. 58, 10, p. 2371-2380 10 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Endoplasmic Reticulum Stress
Endoplasmic Reticulum
Mitochondria
Obesity
10 Citations (Scopus)

Identification of 3-Methylbutanoyl Glycosides in Green Coffea arabica Beans as Causative Determinants for the Quality of Coffee Flavors

Iwasa, K., Setoyama, D., Shimizu, H., Seta, H., Fujimura, Y., Miura, D., Wariishi, H., Nagai, C. & Nakahara, K., Apr 15 2015, In : Journal of Agricultural and Food Chemistry. 63, 14, p. 3742-3751 10 p.

Research output: Contribution to journalArticle

Coffea
Coffee
Beverages
Flavors
Coffea arabica
2014

A case of bleeding duodenal ulcer with pemphigus vulgaris during steroid therapy

Niho, K., Nakasya, A., Ijichi, A., Tsujita, J., Gotoh, K., Shinozaki, H. & Matsumoto, M., Jun 2014, In : Clinical Journal of Gastroenterology. 7, 3, p. 223-227 5 p.

Research output: Contribution to journalArticle

Pemphigus
Duodenal Ulcer
Steroids
Hemorrhage
Blister
48 Citations (Scopus)

Direct induction of ramified microglia-like cells from human monocytes: Dynamic microglial dysfunction in Nasu-Hakola disease

Ohgidani, M., Kato, T. A., Setoyama, D., Sagata, N., Hashimoto, R., Shigenobu, K., Yoshida, T., Hayakawa, K., Shimokawa, N., Miura, D., Utsumi, H. & Kanba, S., May 14 2014, In : Scientific reports. 4, 4957.

Research output: Contribution to journalArticle

Microglia
Monocytes
Cytokines
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
Brain Diseases
9 Citations (Scopus)

Mass spectrometry-based metabolic profiling of gemcitabine-sensitive and gemcitabine-resistant pancreatic cancer cells

Fujimura, Y., Ikenaga, N., Ohuchida, K., Setoyama, D., Irie, M., Miura, D., Wariishi, H., Murata, M., Mizumoto, K., Hashizume, M. & Tanaka, M., Mar 1 2014, In : Pancreas. 43, 2, p. 311-318 8 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Mass Spectrometry
Cell Line
Metabolome
2013
9 Citations (Scopus)

High-Throughput Metabolic Profiling of Diverse Green Coffea arabica Beans Identified Tryptophan as a Universal Discrimination Factor for Immature Beans

Setoyama, D., Iwasa, K., Seta, H., Shimizu, H., Fujimura, Y., Miura, D., Wariishi, H., Nagai, C. & Nakahara, K., Aug 1 2013, In : PloS one. 8, 8, e70098.

Research output: Contribution to journalArticle

Coffea
Coffee
Coffea arabica
metabolomics
Tryptophan
24 Citations (Scopus)

Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells

Setoyama, D., Fujimura, Y. & Miura, D., Dec 1 2013, In : Genes to Cells. 18, 12, p. 1107-1119 13 p.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Metabolomics
Oxidative Stress
Reactive Oxygen Species
Metabolome
2012
38 Citations (Scopus)

Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2

Nishikimi, A., Uruno, T., Duan, X., Cao, Q., Okamura, Y., Saitoh, T., Saito, N., Sakaoka, S., Du, Y., Suenaga, A., Kukimoto-Niino, M., Miyano, K., Gotoh, K., Okabe, T., Sanematsu, F., Tanaka, Y., Sumimoto, H., Honma, T., Yokoyama, S., Nagano, T. & 3 others, Kohda, D., Kanai, M. & Fukui, Y., Apr 20 2012, In : Chemistry and Biology. 19, 4, p. 488-497 10 p.

Research output: Contribution to journalArticle

PDZ Domains
Lymphocytes
Chemical activation
Guanine Nucleotide Exchange Factors
Antigen Receptors
2010
73 Citations (Scopus)

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

Gotoh, K., Tanaka, Y., Nishikimi, A., Nakamura, R., Yamada, H., Maeda, N., Ishikawa, T., Hoshino, K., Uruno, T., Cao, Q., Higashi, S., Kawaguchi, Y., Enjoji, M., Takayanagi, R., Kaisho, T., Yoshikai, Y. & Fukui, Y., Apr 12 2010, In : Journal of Experimental Medicine. 207, 4, p. 721-730 10 p.

Research output: Contribution to journalArticle

Dendritic Cells
Autoimmune Diseases
Nucleic Acids
Antiviral Agents
Immunity
2008
44 Citations (Scopus)

Differential requirement for D0CK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells

Gotoh, K., Tanaka, Y., Nishikimi, A., Inayoshi, A., Enjoji, M., Takayanagi, R., Sasazuki, T. & Fukui, Y., Mar 15 2008, In : Blood. 111, 6, p. 2973-2976 4 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dendritic Cells
Chemotaxis
Spleen
Chemical activation
2007
46 Citations (Scopus)

Mechanism of degradation of CPEB during Xenopus oocyte maturation

Setoyama, D., Yamashita, M. & Sagata, N., Nov 13 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 46, p. 18001-18006 6 p.

Research output: Contribution to journalArticle

Xenopus
Oocytes
Phosphorylation
Ubiquitin-Protein Ligases
Stored Messenger RNA
47 Citations (Scopus)

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2

Tanaka, Y., Hamano, S., Gotoh, K., Murata, Y., Kunisaki, Y., Nishikimi, A., Takii, R., Kawaguchi, M., Inayoshi, A., Masuko, S., Himeno, K., Sasazuki, T. & Fukui, Y., Oct 1 2007, In : Nature Immunology. 8, 10, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

Interleukin-4 Receptors
T-Cell Antigen Receptor
T-Lymphocytes
Down-Regulation
Stathmin