Clinical Immunology & Rheumatology/Infectious Disease

Research Output 1997 2020

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1997
8 Citations (Scopus)

Detection of polymorphisms within the human IL10 receptor cDNA gene sequence by RT-PCR RFLP

Tanaka, Y., Nakashima, H., Otsuka, T., Nemoto, Y., Niiro, H., Yamaoka, K., Ogami, E. I., Arinobu, Y., Tachida, H., Imamura, T. & Niho, Y., Sep 25 1997, In : Immunogenetics. 46, 5, p. 439-441 3 p.

Research output: Contribution to journalArticle

Interleukin-10 Receptors
Interleukin Receptors
Single-Stranded Conformational Polymorphism
Gene Frequency
Restriction Fragment Length Polymorphisms
1998
46 Citations (Scopus)

Activation of STAT5 by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes

Yamaoka, K., Otsuka, T., Niiro, H., Arinobu, Y., Niho, Y., Hamasaki, N. & Izuhara, K., Jan 15 1998, In : Journal of Immunology. 160, 2, p. 838-845 8 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Lipopolysaccharides
Monocytes
Prostaglandin-Endoperoxide Synthases
Granulocytes
98 Citations (Scopus)

MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes

Niiro, H., Otsuka, T., Ogami, E., Yamaoka, K., Nagano, S., Akahoshi, M., Nakashima, H., Arinobu, Y., Izuhara, K. & Niho, Y., Sep 18 1998, In : Biochemical and Biophysical Research Communications. 250, 2, p. 200-205 6 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Interleukin-4
Interleukin-10
Lipopolysaccharides
Monocytes
31 Citations (Scopus)

Propylthiouracil-Induced severe hepatitis: A case report and review of the literature

Ichiki, Y., Akahoshi, M., Yamashita, N., Morita, C., Maruyama, T., Horiuchi, T., Hayashida, K., Ishibashi, H. & Niho, Y., Oct 1 1998, In : Journal of gastroenterology. 33, 5, p. 747-750 4 p.

Research output: Contribution to journalArticle

Propylthiouracil
Hepatitis
Liver
Lymphocytes
Necrosis
1999
66 Citations (Scopus)

Antagonistic effects of an alternative splice variant of human IL-4, IL- 4δ2, on IL-4 activities in human monocytes and B cells

Arinobu, Y., Atamas, S. P., Otsuka, T., Niiro, H., Yamaoka, K., Mitsuyasu, H., Niho, Y., Hamasaki, N., White, B. & Izuhara, K., Feb 1 1999, In : Cellular Immunology. 191, 2, p. 161-167 7 p.

Research output: Contribution to journalArticle

Human Activities
Interleukin-4
Monocytes
B-Lymphocytes
Cytokines
6 Citations (Scopus)

Association of the interleukin-4 receptor α chain with p47(phox), an activator of the phagocyte NADPH oxidase in B cells

Izuhara, K., Arinobu, Y., Sumimoto, H., Nunoi, H., Takeya, R., Higuchi, K., Takeshige, K., Hamasaki, N. & Harada, N., Jan 1 1999, In : Molecular Immunology. 36, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Interleukin-4 Receptors
NADPH Oxidase
Interleukins
Phagocytes
B-Lymphocytes
159 Citations (Scopus)

Cutting edge: Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis

Mitsuyasu, H., Yanagihara, Y., Mao, X. Q., Gao, P. S., Arinobu, Y., Ihara, K., Takabayashi, A., Hara, T., Enomoto, T., Sasaki, S., Kawai, M., Hamasaki, N., Shirakawa, T., Hopkin, J. M. & Izuhara, K., Feb 1 1999, In : Journal of Immunology. 162, 3, p. 1227-1231 5 p.

Research output: Contribution to journalArticle

Interleukin-4 Receptors
Interleukin-4
Immunoglobulin E
Transcriptional Activation
Asthma
63 Citations (Scopus)

Differential response of macrophage subpopulations to myelin degradation in the injured rat sciatic nerve

Hirata, K., Mitoma, H., Ueno, N., He, J. W. & Kawabuchi, M., Dec 1 1999, In : Journal of Neurocytology. 28, 8, p. 685-695 11 p.

Research output: Contribution to journalArticle

Sciatic Nerve
Myelin Sheath
Macrophages
Phagocytosis
Confocal Microscopy
16 Citations (Scopus)

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

Nakashima, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., Nov 1999, In : Rheumatology. 38, 11, p. 1142-1144 3 p.

Research output: Contribution to journalArticle

Interleukin-10 Receptors
Systemic Lupus Erythematosus
Complementary DNA
Genotype
Genes
228 Citations (Scopus)

Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

Akahoshi, M., Nakashima, H., Tanaka, Y., Kohsaka, T., Nagano, S., Ohgami, E., Arinobu, Y., Yamaoka, K., Niiro, H., Shinozaki, M., Hirakata, H., Horiuchi, T., Otsuka, T. & Niho, Y., Aug 1 1999, In : Arthritis and rheumatism. 42, 8, p. 1644-1648 5 p.

Research output: Contribution to journalArticle

Th1-Th2 Balance
Helper-Inducer T-Lymphocytes
Systemic Lupus Erythematosus
Th2 Cells
Lupus Nephritis
53 Citations (Scopus)

The combination of polymorphisms within interferon-γ receptor I and receptor 2 associated with the risk of systemic lupus erythematosus

Nakashima, H., Inoue, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., Jun 18 1999, In : FEBS Letters. 453, 1-2, p. 187-190 4 p.

Research output: Contribution to journalArticle

Interferon Receptors
Polymorphism
Systemic Lupus Erythematosus
Amino Acids
Genotype
2 Citations (Scopus)

Two polymorphisms within interleukin-3 (hlL3) gene detected by mismatch PCR/RFLP

Nakashima, H., Otsuka, T., Ohba, Y., Akahoshi, M., Nagano, S., Ogami, E., Arinobu, Y., Miyake, K., Inoue, Y., Niiro, H., Kaji, Y. & Niho, Y., Jan 1 1999, In : Genes and Immunity. 1, 2, p. 156-158 3 p.

Research output: Contribution to journalArticle

Interleukin-3
Nucleic Acid Databases
Restriction Fragment Length Polymorphisms
Thymine
Cytosine
2000
9 Citations (Scopus)

Augmentation of signal transducer and activation of transcription (STAT)6 and STAT3 expression in stimulated B and T cells

Arinobu, Y., Sugimoto, R., Akaiwa, M., Arima, K., Otsuka, T., Hamasaki, N. & Izuhara, K., Oct 22 2000, In : Biochemical and Biophysical Research Communications. 277, 2, p. 317-324 8 p.

Research output: Contribution to journalArticle

T-cells
Interleukin-13
Transcription
Transducers
Interleukin-4
370 Citations (Scopus)

Genetic variants of IL-13 signalling and human asthma and atopy

Heinzmann, A., Mao, X. Q., Akaiwa, M., Kreomer, R. T., Gao, P. S., Ohshima, K., Umeshita, R., Abe, Y., Braun, S., Yamashita, T., Roberts, M. H., Sugimoto, R., Arima, K., Arinobu, Y., Yu, B., Kruse, S., Enomoto, T., Dake, Y., Kawai, M., Shimazu, S. & 12 others, Sasaki, S., Adra, C. N., Kitaichi, M., Inoue, H., Yamauchi, K., Tomichi, N., Kurimoto, F., Hamasaki, N., Hopkin, J. M., Izuhara, K., Shirakawa, T. & Deichmann, K. A., Mar 1 2000, In : Human Molecular Genetics. 9, 4, p. 549-559 11 p.

Research output: Contribution to journalArticle

Interleukin-13
Asthma
Immunoglobulin E
Smooth Muscle
Chromosomes
2001
106 Citations (Scopus)

Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese molecular and functional analysis

Morita, C., Horiuchi, T., Tsukamoto, H., Hatta, N., Kikuchi, Y., Arinobu, Y., Otsuka, T., Sawabe, T., Harashima, S. I., Nagasawa, K. & Niho, Y., Dec 1 2001, In : Arthritis and rheumatism. 44, 12, p. 2819-2827 9 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type II
Tumor Necrosis Factor Receptors
Systemic Lupus Erythematosus
Exons
HeLa Cells
181 Citations (Scopus)

Predominance of Th1 Immune Response in Diffuse Proliferative Lupus Nephritis

Masutani, K., Akahoshi, M., Tsuruya, K., Tokumoto, M., Ninomiya, T., Kohsaka, T., Fukuda, K., Kanai, H., Nakashima, H., Otsuka, T. & Hirakata, H., Sep 2001, In : Arthritis and rheumatism. 44, 9, p. 2097-2106 10 p.

Research output: Contribution to journalArticle

Lupus Nephritis
Systemic Lupus Erythematosus
Kidney
Nephritis
Th1-Th2 Balance
2002
115 Citations (Scopus)

Association between IL-4 genotype and IL-4 production in the Japanese population

Nakashima, H., Miyake, K., Inoue, Y., Shimizu, S., Akahoshi, M., Tanaka, Y., Otsuka, T. & Harada, M., Apr 1 2002, In : Genes and Immunity. 3, 2, p. 107-109 3 p.

Research output: Contribution to journalArticle

Interleukin-4
Genotype
Population
Haplotypes
Cytokines
61 Citations (Scopus)

Genetically determined interferon-γ production influences the histological phenotype of lupus nephritis

Miyake, K., Nakashima, H., Akahoshi, M., Inoue, Y., Nagano, S., Tanaka, Y., Masutani, K., Hirakata, H., Gondo, H., Otsuka, T. & Harada, M., Jun 8 2002, In : Rheumatology. 41, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

Lupus Nephritis
Interferons
Phenotype
Genotype
Genes
44 Citations (Scopus)

Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: Involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines

Nagano, S., Otsuka, T., Niiro, H., Yamaoka, K., Arinobu, Y., Ogami, E., Akahoshi, M., Inoue, Y., Miyake, K., Nakashima, H., Niho, Y. & Harada, M., Aug 7 2002, In : International Immunology. 14, 7, p. 733-740 8 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Mitogen-Activated Protein Kinases
Lipopolysaccharides
Neutrophils
Anti-Inflammatory Agents
2003
92 Citations (Scopus)

Influence of interleukin-12 receptor β1 polymorphisms on tuberculosis

Akahoshi, M., Nakashima, H., Miyake, K., Inoue, Y., Shimizu, S., Tanaka, Y., Okada, K., Otsuka, T. & Harada, M., Mar 1 2003, In : Human Genetics. 112, 3, p. 237-243 7 p.

Research output: Contribution to journalArticle

Interleukin-12 Receptors
Tuberculosis
Alleles
Interleukin-12
Genes
78 Citations (Scopus)

Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis

Shimoda, S., Nakamura, M., Ishibashi, H., Kawano, A., Kamihira, T., Sakamoto, N., Matsushita, S., Tanaka, A., Worman, H. J., Gershwin, M. E. & Harada, M., Jul 1 2003, In : Gastroenterology. 124, 7, p. 1915-1925 11 p.

Research output: Contribution to journalArticle

Molecular Mimicry
Biliary Liver Cirrhosis
Autoantigens
Peptides
Antinuclear Antibodies
3 Citations (Scopus)

Mutation detection using RT-PCR-RFLP.

Nakashima, H., Akahoshi, M. & Tanaka, Y., 2003, In : Methods in molecular biology (Clifton, N.J.). 226, p. 319-322 4 p.

Research output: Contribution to journalArticle

DNA Primers
Reverse Transcriptase Polymerase Chain Reaction
Restriction Fragment Length Polymorphisms
Complementary DNA
Polymerase Chain Reaction
23 Citations (Scopus)

Promiscuous T cells selected by Escherichia coli: OGDC-E2 in primary biliary cirrhosis

Tanimoto, H., Shimoda, S., Nakamura, M., Ishibashi, H., Kawano, A., Kamihira, T., Matsushita, S., Gershwin, M. E. & Harada, M., May 2003, In : Journal of Autoimmunity. 20, 3, p. 255-263 9 p.

Research output: Contribution to journalArticle

dihydrolipoamide succinyltransferase
Biliary Liver Cirrhosis
Escherichia coli
T-Lymphocytes
Clone Cells
19 Citations (Scopus)

Strong polarization toward th1 immune response in ANCA-associated glomerulonephritis

Masutani, K., Tokumoto, M., Nakashima, H., Tsuruya, K., Kashiwagi, M., Kudoh, Y., Fukuda, K., Kanai, H., Akahoshi, M., Otsuka, T., Hirakata, H. & Ida, M., Jun 1 2003, In : Clinical nephrology. 59, 6, p. 395-405 11 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Glomerulonephritis
Osteopontin
Macrophages
T-Lymphocytes
6 Citations (Scopus)

Systemic vasculitis associated with α1-antitrypsin deficiency

Takii, Y., Inoue, H., Karashima, E., Akahoshi, M., Furugo, I., Hattori, S., Yamanaka, M., Kinoshita, S., Hamasaki, N., Shimoda, K., Nakashima, H., Tsukamoto, H., Horiuchi, T., Otsuka, T. & Harada, M., Jul 1 2003, In : Internal Medicine. 42, 7, p. 619-623 5 p.

Research output: Contribution to journalArticle

Systemic Vasculitis
Peptide Hydrolases
Protease Inhibitors
Leukocyte Elastase
Serine Proteases
2004
76 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice

Shimizu, S., Nakashima, H., Masutani, K., Inoue, Y., Miyake, K., Akahoshi, M., Tanaka, Y., Egashira, K., Hirakata, H., Otsuka, T. & Harada, M., Sep 1 2004, In : Rheumatology. 43, 9, p. 1121-1128 8 p.

Research output: Contribution to journalArticle

Inbred MRL lpr Mouse
Nephritis
Chemokine CCL2
Genetic Therapy
Lupus Nephritis
10 Citations (Scopus)

Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma

Hirota, T., Obara, K., Matsuda, A., Akahoshi, M., Nakashima, K., Hasegawa, K., Takahashi, N., Shimizu, M., Sekiguchi, H., Kokubo, M., Doi, S., Fujiwara, H., Miyatake, A., Fujita, K., Enomoto, T., Kishi, F., Suzuki, Y., Saito, H., Nakamura, Y., Shirakawa, T. & 1 others, Tamari, M., Jan 1 2004, In : Journal of Human Genetics. 49, 7, p. 370-375 6 p.

Research output: Contribution to journalArticle

Asthma
Interferon-gamma
Genes
Epithelial Cells
Proteins
64 Citations (Scopus)

Association between IFNA genotype and the risk of sarcoidosis

Akahoshi, M., Ishihara, M., Remus, N., Uno, K., Miyake, K., Hirota, T., Nakashima, K., Matsuda, A., Kanda, M., Enomoto, T., Ohno, S., Nakashima, H., Casanova, J. L., Hopkin, J. M., Tamari, M., Mao, X. Q. & Shirakawa, T., Apr 1 2004, In : Human Genetics. 114, 5, p. 503-509 7 p.

Research output: Contribution to journalArticle

Sarcoidosis
Genotype
Alleles
Tuberculosis
Genes
12 Citations (Scopus)

Association of A Four-Amino Acid Residue Insertion Polymorphism of the HS1 Gene with Systemic Lupus Erythematosus: Molecular and Functional Analysis

Otsuka, J., Horiuchi, T., Yoshizawa, S., Tsukamoto, H., Sawabe, T., Kikuchi, Y., Himeji, D., Koyama, T., Mitoma, H., Watanabe, T. & Harada, M., Mar 1 2004, In : Arthritis and rheumatism. 50, 3, p. 871-881 11 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
B-Lymphocytes
Amino Acids
Genes
Proline
24 Citations (Scopus)

Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells

Ishikawa, F., Yasukawa, M., Yoshida, S., Nakamura, K. I., Nagatoshi, Y., Kanemaru, T., Shimoda, K., Shimoda, S., Miyamoto, T., Okamura, J., Shultz, L. D. & Harada, M., Dec 1 2004, In : FASEB Journal. 18, 15, p. 1958-1960 3 p.

Research output: Contribution to journalArticle

CD34 Antigens
Inbred NOD Mouse
SCID Mice
Hematopoietic Stem Cell Transplantation
Intestinal Mucosa
24 Citations (Scopus)

MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: Case report and review of the literature

Akahoshi, M., Yoshimoto, G., Nakashima, H., Miyake, K., Inoue, Y., Tanaka, Y., Tsukamoto, H., Horiuchi, T., Otsuka, T. & Harada, M., Jun 1 2004, In : Modern Rheumatology. 14, 2, p. 179-183 5 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Granulomatosis with Polyangiitis
Meningitis
Cranial Nerve Diseases
Headache Disorders
6 Citations (Scopus)

Myeloid/natural killer cell blast crisis representing an additional translocation, t(3;7)(q26;q21) in Philadelphia-positive chronic myelogenous leukemia

Henzan, H., Yoshimoto, G., Okeda, A., Nagasaki, Y., Hirano, G., Takase, K., Tanimoto, T., Miyamoto, T., Fukuda, T., Nagafuji, K. & Harada, M., Dec 1 2004, In : Annals of Hematology. 83, 12, p. 784-788 5 p.

Research output: Contribution to journalArticle

Blast Crisis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Natural Killer Cells
Philadelphia Chromosome
Cytogenetic Analysis
20 Citations (Scopus)

Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese.

Horiuchi, T., Tsukamoto, H., Mitoma, H., Miyagawa, H., Tamimoto, Y., Yoshizawa, S., Harada, M., Hayashi, K., Hashimura, C., Oribe, M. & Okamura, S., Jan 1 2004, In : International journal of molecular medicine. 14, 5, p. 813-818 6 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Mutation
Rheumatoid Arthritis
Missense Mutation
Autosomal Dominant Familial Periodic Fever
28 Citations (Scopus)

Novel Regulatory Mechanisms of CD40-Induced Prostanoid Synthesis by IL-4 and IL-10 in Human Monocytes

Inoue, Y., Otsuka, T., Niiro, H., Nagano, S., Arinobu, Y., Ogami, E., Akahoshi, M., Miyake, K., Ninomiya, I., Shimizu, S., Nakashima, H. & Harada, M., Feb 15 2004, In : Journal of Immunology. 172, 4, p. 2147-2154 8 p.

Research output: Contribution to journalArticle

Interleukin-4
Interleukin-10
Prostaglandins
Monocytes
Phosphotransferases
2005
139 Citations (Scopus)

Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis

Mao, T. K., Lian, Z. X., Selmi, C., Ichiki, Y., Ashwood, P., Ansari, A. A., Coppel, R. L., Shimoda, S., Ishibashi, H. & Gershwin, M. E., Oct 1 2005, In : Hepatology. 42, 4, p. 802-808 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Toll-Like Receptors
Monocytes
Ligands
Cytokines
88 Citations (Scopus)

Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis

Nakamura, M., Shimizu-Yoshida, Y., Takii, Y., Komori, A., Yokoyama, T., Ueki, T., Daikoku, M., Yano, K., Matsumoto, T., Migita, K., Yatsuhashi, H., Ito, M., Masaki, N., Adachi, H., Watanabe, Y., Nakamura, Y., Saoshiro, T., Sodeyama, T., Koga, M., Shimoda, S. & 1 others, Ishibashi, H., Mar 2005, In : Journal of Hepatology. 42, 3, p. 386-392 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Ursodeoxycholic Acid
Anti-Idiotypic Antibodies
Liver Failure
Peptides
5 Citations (Scopus)

Association between IFNA genotype and the risk of systemic lupus erythematosus

Nakashima, H., Matsuno, S., Akahoshi, M., Miyake, K., Inoue, Y., Tanaka, Y., Ninomiya, I., Shimizu, S., Igawa, T., Sadanaga, A., Otsuka, T. & Harada, M., Feb 1 2005, In : Clinical Rheumatology. 24, 1, p. 38-40 3 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Interferons
Genotype
Autoantigens
Antigen-Presenting Cells
52 Citations (Scopus)

Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologus PBSCT

Horiuchi, T., Gondo, H., Miyagawa, H., Otsuka, J., Inaba, S., Nagafuji, K., Takase, K., Tsukamoto, H., Koyama, T., Mitoma, H., Tamimoto, Y., Miyagi, Y., Tahira, T., Hayashi, K., Hashimura, C., Okamura, S. & Harada, M., Mar 1 2005, In : Genes and Immunity. 6, 2, p. 162-166 5 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Bacterial Infections
Peripheral Blood Stem Cell Transplantation
Gene Frequency
Drug Therapy
38 Citations (Scopus)

Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes

Takahashi, N., Akahoshi, M., Matsuda, A., Ebe, K., Inomata, N., Obara, K., Hirota, T., Nakashima, K., Shimizu, M., Tamari, M., Doi, S., Miyatake, A., Enomoto, T., Nakashima, H., Ikezawa, Z. & Shirakawa, T., Nov 1 2005, In : Human Molecular Genetics. 14, 21, p. 3149-3159 11 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Immunoglobulin E
Phenotype
Interleukin-12
Cytokines
46 Citations (Scopus)

Biliary epithelial cells regulate autoreactive T cells: Implications for biliary-specific diseases

Kamihira, T., Shimoda, S., Nakamura, M., Yokoyama, T., Takii, Y., Kawano, A., Handa, M., Ishibashi, H., Gershwin, M. E. & Harada, M., Jan 1 2005, In : Hepatology. 41, 1, p. 151-159 9 p.

Research output: Contribution to journalArticle

Epithelial Cells
T-Lymphocytes
Biliary Liver Cirrhosis
HLA Antigens
Dinoprostone
6 Citations (Scopus)

Body surface area is an independent factor contributing to the effects of lamivudine treatment

Nakamuta, M., Kotoh, K., Tanabe, Y., Kajiwara, E., Shimono, J., Masumoto, A., Maruyama, T., Furusyo, N., Nomura, H., Sakai, H., Takahashi, K., Azuma, K., Shimoda, S., Enjoji, M., Hayashi, J., Sugimoto, R., Amagase, H., Tominaga, S., Yanagita, K., Ogiwara, K. & 18 others, Tokumatsu, M., Tabata, S., Yokota, M., Tanaka, H., Nagase, S., Tsuruta, S., Tada, S., Nagano, M., Honda, M., Umeno, T., Sugimura, T., Ueno, S., Miki, K., Okubo, H., Fujimoto, H., Higuchi, N., Shigematsu, S. & Higashi, N., Jan 1 2005, In : Hepatology Research. 31, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

Lamivudine
Body Surface Area
Hepatitis B e Antigens
Alanine Transaminase
DNA
91 Citations (Scopus)

Characterization and distribution of bone marrow-derived cells in mouse cornea

Nakamura, T., Ishikawa, F., Sonoda, K. H., Hisatomi, T., Qiao, H., Yamada, J., Fukata, M., Ishibashi, T., Harada, M. & Kinoshita, S., Feb 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 2, p. 497-503 7 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Cornea
Hematopoietic Stem Cells
Corneal Stroma
Bone Marrow
40 Citations (Scopus)

Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.

Mitoma, H., Horiuchi, T., kimoto, Y., Tsukamoto, H., Uchino, A., Tamimoto, Y., Miyagi, Y. & Harada, M., Jan 1 2005, In : International journal of molecular medicine. 16, 4, p. 609-615 7 p.

Research output: Contribution to journalArticle

Interleukin-21 Receptors
Systemic Lupus Erythematosus
B-Lymphocytes
B-Lymphocyte Subsets
Lymphopenia
256 Citations (Scopus)

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E. A., Iwasaki-Arai, J., Mizuno, S. I., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., Fenyus, M. L., Elf, S., Chan, S., Kastner, P., Huettner, C. S., Murray, R., Tenen, D. G. & Akashi, K., Sep 1 2005, In : Blood. 106, 5, p. 1590-1600 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Cell Differentiation
Maintenance
B-Lymphocytes
107 Citations (Scopus)

Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts

Isse, K., Harada, K., Zen, Y., Kamihira, T., Shimoda, S., Harada, M. & Nakanuma, Y., Mar 1 2005, In : Hepatology. 41, 3, p. 506-516 11 p.

Research output: Contribution to journalArticle

Chemokine CX3CL1
Intrahepatic Bile Ducts
Lymphocytes
Biliary Liver Cirrhosis
Epithelial Cells
68 Citations (Scopus)

Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma

Akahoshi, M., Obara, K., Hirota, T., Matsuda, A., Hasegawa, K., Takahashi, N., Shimizu, M., Nakashima, K., Cheng, L., Doi, S., Fujiwara, H., Miyatake, A., Fujita, K., Higashi, N., Taniguchi, M., Enomoto, T., Mao, X. Q., Nakashima, H., Adra, C. N., Nakamura, Y. & 2 others, Tamari, M. & Shirakawa, T., Jun 1 2005, In : Human Genetics. 117, 1, p. 16-26 11 p.

Research output: Contribution to journalArticle

Aspirin Induced Asthma
Asthma
Single Nucleotide Polymorphism
Genes
Phenotype
66 Citations (Scopus)

Human cord blood-derived cells generate insulin-producing cells in vivo

Yoshida, S., Ishikawa, F., Kawano, N., Shimoda, K., Nagafuchi, S., Shimoda, S., Yasukawa, M., Kanemaru, T., Ishibashi, H., Shultz, L. D. & Harada, M., Oct 1 2005, In : STEM CELLS. 23, 9, p. 1409-1416 8 p.

Research output: Contribution to journalArticle

Fetal Blood
Blood Cells
Insulin
Human Chromosomes
Fluorescence In Situ Hybridization
131 Citations (Scopus)

Identification of eosinophil lineage-committed progenitors in the murine bone marrow

Iwasaki, H., Mizuno, S. I., Mayfield, R., Shigematsu, H., Arinobu, Y., Seed, B., Gurish, M. F., Takatsu, K. & Akashi, K., Jun 20 2005, In : Journal of Experimental Medicine. 201, 12, p. 1891-1897 7 p.

Research output: Contribution to journalArticle

Eosinophils
Bone Marrow
Monocytes
Granulocyte Precursor Cells
Mast Cells
221 Citations (Scopus)

Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-α

Mitoma, H., Horiuchi, T., Hatta, N., Tsukamoto, H., Harashima, S. I., Kikuchi, Y., Otsuka, J., Okamura, S., Fujita, S. & Harada, M., Jan 1 2005, In : Gastroenterology. 128, 2, p. 376-392 17 p.

Research output: Contribution to journalArticle

Anti-Inflammatory Agents
Tumor Necrosis Factor-alpha
Apoptosis
E-Selectin
JNK Mitogen-Activated Protein Kinases
7 Citations (Scopus)

Influence of interferon therapy on signal-averaged and ambulatory electrocardiograms in patients with chronic active hepatitis

Hiramatsu, S. I., Maruyama, T., Ito, H., Shimoda, S., Kaji, Y. & Harada, M., Dec 1 2005, In : International heart journal. 46, 6, p. 1033-1040 8 p.

Research output: Contribution to journalArticle

Chronic Hepatitis
Interferons
Electrocardiography
Cardiac Arrhythmias
Therapeutics