Research Output 2002 2018

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2018

Competencies necessary for becoming a leader in the field of community medicine: A Japanese qualitative interview study

Kainuma, M., Kikukawa, M., Nagata, M. & Yoshida, M., Apr 1 2018, In : BMJ open. 8, 4, e020082.

Research output: Contribution to journalArticle

Community Medicine
Aptitude
Interviews
Curriculum
Local Government
5 Citations (Scopus)

Secondary syphilis with pulmonary involvement

Ohta, A., Furusyo, N., Kishihara, Y., Eiraku, K., Murata, M., Kainuma, M., Toyoda, K., Ogawa, E., Hayashi, T. & Koga, T., Jan 1 2018, In : Internal Medicine. 57, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

Exanthema
Amoxicillin
Lung
Thorax
Tomography
2017
3 Citations (Scopus)

The traditional Japanese herbal medicine Hachimijiogan Elicits neurite outgrowth effects in PC12 cells and improves cognitive in AD model rats via phosphorylation of CREB

Kubota, K., Fukue, H., Sato, H., Hashimoto, K., Fujikane, A., Moriyama, H., Watanabe, T., Katsurabayashi, S., Kainuma, M. & Iwasaki, K., Nov 21 2017, In : Frontiers in Pharmacology. 8, NOV, 850.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Herbal Medicine
PC12 Cells
Alzheimer Disease
Phosphorylation
2016
4 Citations (Scopus)

Association of IL28B rs8099917 genotype and female sex with spontaneous clearance of hepatitis C virus infection: a Japanese cross-sectional study

Ikezaki, H., Furusyo, N., Hiramine, S., Ura, K., Mitsumoto-Kaseida, F., Takayama, K., Shimizu, M., Toyoda, K., Ogawa, E., Kainuma, M., Murata, M. & Hayashi, J., Mar 1 2016, In : Archives of Virology. 161, 3, p. 641-648 8 p.

Research output: Contribution to journalArticle

Interleukins
Virus Diseases
Hepacivirus
Cross-Sectional Studies
Genotype
Kampo Medicine
Body Composition
Electric Impedance
Edema
Muscles
3 Citations (Scopus)

The relation between hepatotoxicity and the total coumarin intake from traditional Japanese medicines containing cinnamon bark

Iwata, N., Kainuma, M., Kobayashi, D., Kubota, T., Sugawara, N., Uchida, A., Ozono, S., Yamamuro, Y., Furusyo, N., Ueda, K., Tahara, E. & Shimazoe, T., Jun 20 2016, In : Frontiers in Pharmacology. 7, JUN, 174.

Research output: Contribution to journalArticle

Kampo Medicine
Cinnamomum zeylanicum
Traditional Medicine
No-Observed-Adverse-Effect Level
coumarin
3 Citations (Scopus)

The relation of postprandial plasma glucose and serum endostatin to the urinary albumin excretion of residents with prediabetes: results from the Kyushu and Okinawa Population Study (KOPS)

Shimizu, M., Furusyo, N., Tanaka, Y., Kato, Y., Mitsumoto-Kaseida, F., Takayama, K., Ura, K., Hiramine, S., Hayashi, T., Ikezaki, H., Ihara, T., Mukae, H., Ogawa, E., Toyoda, K., Kainuma, M., Murata, M. & Hayashi, J., Jun 1 2016, In : International Urology and Nephrology. 48, 6, p. 851-857 7 p.

Research output: Contribution to journalArticle

Endostatins
Prediabetic State
Albumins
Glucose
Serum
2015

A case of granulomatosis with polyangiitis preceded by subacute thyroiditis

Mukae, H., Furusyo, N., Murata, M., Ogawa, E., Kainuma, M., Shimizu, M., Ihara, T. & Hayashi, J., Mar 1 2015, In : Clinical Case Reports. 3, 3, p. 139-144 6 p.

Research output: Contribution to journalArticle

Subacute Thyroiditis
Granulomatosis with Polyangiitis
Thyroid Diseases
Autoimmune Diseases
17 Citations (Scopus)

Subclinical carotid atherosclerosis and triglycerides predict the incidence of chronic kidney disease in the Japanese general population: Results from the Kyushu and Okinawa Population Study (KOPS)

Shimizu, M., Furusyo, N., Mitsumoto, F., Takayama, K., Ura, K., Hiramine, S., Ikezaki, H., Ihara, T., Mukae, H., Ogawa, E., Toyoda, K., Kainuma, M., Murata, M. & Hayashi, J., Feb 1 2015, In : Atherosclerosis. 238, 2, p. 207-212 6 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Chronic Renal Insufficiency
Carotid Intima-Media Thickness
Triglycerides
Incidence
5 Citations (Scopus)

The association between objective tongue color and endoscopic findings: Results from the Kyushu and Okinawa population study (KOPS)

Kainuma, M., Furusyo, N., Urita, Y., Nagata, M., Ihara, T., Oji, T., Nakaguchi, T., Namiki, T. & Hayashi, J., Oct 16 2015, In : BMC Complementary and Alternative Medicine. 15, 1

Research output: Contribution to journalArticle

Tongue
Color
Pylorus
Atrophic Gastritis
Population
2014
2 Citations (Scopus)
Ribavirin
Hemophilia A
Virus Diseases
Coinfection
Hepacivirus
4 Citations (Scopus)

Nocturnal difference in the ultra low frequency band of heart rate variability in patients stratified by Kampo medicine prescription

Kainuma, M., Furusyo, N., Ando, S. I., Mukae, H., Ogawa, E., Toyoda, K., Murata, M. & Hayashi, J., 2014, In : Circulation Journal. 78, 8, p. 1924-1927 4 p.

Research output: Contribution to journalArticle

Kampo Medicine
Prescriptions
Heart Rate
Sleep Stages
Sleep
16 Citations (Scopus)

Therapeutic drug monitoring of telaprevir in chronic hepatitis C patients receiving telaprevir-based triple therapy is useful for predicting virological response

Furusyo, N., Ogawa, E., Murata, M., Toyoda, K., Ohnishi, H., Eiraku, K., Shimizu, M., Harada, Y., Mitsumoto, F., Takayama, K., Kainuma, M., Okada, K. & Hayashi, J., Feb 1 2014, In : Journal of Antimicrobial Chemotherapy. 69, 2, p. 483-490 8 p., dkt371.

Research output: Contribution to journalArticle

Drug Monitoring
Chronic Hepatitis C
Ribavirin
Therapeutics
Interferons
8 Citations (Scopus)

The utility of urinary myo-inositol as a marker of glucose intolerance

Ikezaki, H., Furusyo, N., Okada, K., Ihara, T., Hayashi, T., Ogawa, E., Kainuma, M., Murata, M. & Hayashi, J., Jan 1 2014, In : Diabetes Research and Clinical Practice. 103, 1, p. 88-96 9 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Inositol
Fasting
Glucose
ROC Curve
2013

A case of Fanconi's syndrome caused by long-term administration of adefovir by a patient with chronic hepatitis B

Kumade, E., Furusyo, N., Mitsumoto, F., Ogawa, E., Toyoda, K., Kainuma, M., Masayuki, M. & Hayashi, J., Jan 1 2013, In : Acta Hepatologica Japonica. 54, 3, p. 187-193 7 p.

Research output: Contribution to journalArticle

Fanconi Syndrome
Chronic Hepatitis B
Uric Acid
Alkaline Phosphatase
Leg

A case report of human immunodeficiency virus-associated anaplastic lymphoma kinase protein-negative anaplastic large cell lymphoma

Taniai, H., Furusyo, N., Murata, M., Mitsumoto, F., Shimizu, M., Toyoda, K., Ogawa, E., Kainuma, M., Okada, K. & Hayashi, J., Jan 1 2013, In : SpringerPlus. 2, 1, p. 1-5 5 p., 400.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
HIV
Proteins
Fever of Unknown Origin
Groin
4 Citations (Scopus)

Association between chronic hepatitis C virus infection and high levels of circulating N-terminal pro-brain natriuretic peptide

Okada, K., Furusyo, N., Ogawa, E., Ikezaki, H., Ihara, T., Hayashi, T., Kainuma, M., Murata, M. & Hayashi, J., Feb 1 2013, In : Endocrine. 43, 1, p. 200-205 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Chronic Hepatitis C
Virus Diseases
Hepacivirus
Infection
19 Citations (Scopus)

Early phase viral kinetics of chronic hepatitis C patients receiving telaprevir-based triple therapy: A comparison of two real-time PCR assays

Ogawa, E., Furusyo, N., Masayuki, M., Toyoda, K., Eiraku, K., Shimizu, M., Harada, Y., Mitsumoto, F., Takayama, K., Okada, K., Kainuma, M. & Hayashi, J., Aug 1 2013, In : Antiviral Research. 99, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Real-Time Polymerase Chain Reaction
RNA
Therapeutics
9 Citations (Scopus)

Investigation of Encephalopathy Caused by Shiga Toxin 2c-Producing Escherichia coli Infection in Mice

Amran, M. Y., Fujii, J., Suzuki, S. O., Kolling, G. L., Villanueva, S. Y. A. M., Kainuma, M., Kobayashi, H., Kameyama, H. & Yoshida, S. I., Mar 13 2013, In : PloS one. 8, 3, e58959.

Research output: Contribution to journalArticle

Shiga Toxin
medulla oblongata
Shiga-Toxigenic Escherichia coli
Shiga toxin
Escherichia coli Infections
4 Citations (Scopus)

Proposal for effective treatment of Shiga toxin-producing Escherichia coli infection in mice

Amran, M. Y., Fujii, J., Kolling, G. L., Villanueva, S. Y. A. M., Kainuma, M., Kobayashi, H., Kameyama, H. & Yoshida, S. I., Dec 1 2013, In : Microbial Pathogenesis. 65, p. 57-62 6 p.

Research output: Contribution to journalArticle

Shiga-Toxigenic Escherichia coli
Escherichia coli Infections
Azithromycin
Feces
Fosfomycin
Kampo Medicine
Ribavirin
Traditional Medicine
Chronic Hepatitis C
Interferons
10 Citations (Scopus)

The serum undercarboxylated osteocalcin level and the diet of a Japanese population: Results from the Kyushu and Okinawa Population Study (KOPS)

Furusyo, N., Ihara, T., Hayashi, T., Ikezaki, H., Toyoda, K., Ogawa, E., Okada, K., Kainuma, M., Murata, M. & Hayashi, J., Jun 1 2013, In : Endocrine. 43, 3, p. 635-642 8 p.

Research output: Contribution to journalArticle

Osteocalcin
Diet
Serum
Population
Vitamin K
2 Citations (Scopus)

Valuable antiviral therapeutic options for the treatment of chronic hepatitis C patients with thrombocytopenia

Ogawa, E., Furusyo, N., Murata, M., Ikezaki, H., Ihara, T., Hayashi, T., Toyoda, K., Okada, K., Kainuma, M., Kajiwara, E., Takahashi, K., Satoh, T. & Hayashi, J., Dec 1 2013, In : Journal of Viral Hepatitis. 20, 12, p. 838-846 9 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Thrombocytopenia
Antiviral Agents
Genotype
Insulin Resistance
2012
2 Citations (Scopus)
Immune Reconstitution Inflammatory Syndrome
hepatitis
human immunodeficiency virus
Hepatitis B Surface Antigens
antigen
2 Citations (Scopus)

A hypertriglyceridemic state increases high sensitivity C-reactive protein of Japanese men with normal glucose tolerance

Okada, K., Furusyo, N., Murata, M., Sawayama, Y., Kainuma, M. & Hayashi, J., Feb 1 2012, In : Endocrine. 41, 1, p. 96-102 7 p.

Research output: Contribution to journalArticle

Hypertriglyceridemia
C-Reactive Protein
Glucose
Fasting
Triglycerides

Combination therapy with tsumyakushigyakuto (tong-mai-si-ni-tang) and sekiganryo (chi-wan-liao) and the sequence of medication

Yano, H., Tahara, E., Iwanaga, J., Inutsuka, H., Kubota, M., Kainuma, M., Kimura, H., Kuriyama, K. & Mitsuma, T., Jan 1 2012, In : Journal of Traditional Medicines. 29, 2, p. 74-80 7 p.

Research output: Contribution to journalArticle

Fatigue
Therapeutics
Acupuncture
Chronic Fatigue Syndrome
Induced Hyperthermia
31 Citations (Scopus)

Insulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1

Ogawa, E., Furusyo, N., Murata, M., Ikezaki, H., Ihara, T., Hayashi, T., Toyoda, K., Taniai, H., Okada, K., Kainuma, M. & Hayashi, J., Sep 1 2012, In : Journal of Hepatology. 57, 3, p. 534-540 7 p.

Research output: Contribution to journalArticle

Ribavirin
Chronic Hepatitis C
Insulin Resistance
Genotype
Homeostasis
4 Citations (Scopus)

Pegylated interferon α-2b plus ribavirin for Japanese chronic hepatitis C patients with normal alanine aminotransferase

Kainuma, M., Furusyo, N., Azuma, K., Kajiwara, E., Takahashi, K., Nomura, H., Tanabe, Y., Satoh, T., Maruyama, T., Nakamuta, M., Kotoh, K., Shimoda, S. & Hayashi, J., Jan 1 2012, In : Hepatology Research. 42, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Ribavirin
Chronic Hepatitis C
Alanine Transaminase
Interferons
Hepacivirus
34 Citations (Scopus)

Raloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: A randomized trial

Furusyo, N., Ogawa, E., Sudoh, M., Murata, M., Ihara, T., Hayashi, T., Ikezaki, H., Hiramine, S., Mukae, H., Toyoda, K., Taniai, H., Okada, K., Kainuma, M., Kajiwara, E. & Hayashi, J., Dec 1 2012, In : Journal of Hepatology. 57, 6, p. 1186-1192 7 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Standard of Care
Antiviral Agents
Interleukins
Ribavirin
2011

[A case of AIDS-associated Kaposi's sarcoma with systemic invasion].

Ikezaki, H., Ogawa, E., Murata, M., Ihara, T., Toyoda, K., Taniai, H., Otaguro, S., Kainuma, M., Sawayama, Y., Furusyo, N. & Hayashi, J., Jan 2011, In : Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 85, 1, p. 54-58 5 p.

Research output: Contribution to journalArticle

Kaposi's Sarcoma
Acquired Immunodeficiency Syndrome
Highly Active Antiretroviral Therapy
Anorexia
CD4 Lymphocyte Count
4 Citations (Scopus)

Abbott RealTime PCR assay is useful for evaluating virological response to antiviral treatment for chronic hepatitis C

Ikezaki, H., Furusyo, N., Ihara, T., Hayashi, T., Ogawa, E., Toyoda, K., Taniai, H., Kainuma, M., Murata, M. & Hayashi, J., Dec 2011, In : Journal of Infection and Chemotherapy. 17, 6, p. 737-743 7 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Antiviral Agents
Hepacivirus
Polymerase Chain Reaction
RNA

A case of type I diabetes mellitus caused by low-dose, long-term natural interferon a therapy for a patient with chronic hepatitis C

Hayashi, T., Kainuma, M., Taniai, H., Murata, M., Okada, K., Sawayama, Y., Furusyo, N. & Hayashi, J., Jul 14 2011, In : Acta Hepatologica Japonica. 52, 6, p. 335-343 9 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Type 1 Diabetes Mellitus
Interferons
Blood Glucose
RNA
41 Citations (Scopus)

Longitudinal assessment of liver stiffness by transient elastography for chronic hepatitis B patients treated with nucleoside analog

Ogawa, E., Furusyo, N., Murata, M., Ohnishi, H., Toyoda, K., Taniai, H., Ihara, T., Ikezaki, H., Hayashi, T., Kainuma, M. & Hayashi, J., Dec 1 2011, In : Hepatology Research. 41, 12, p. 1178-1188 11 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis B
Nucleosides
Liver
Therapeutics
22 Citations (Scopus)

Ribavirin concentration in the later stages of 48 week pegylated interferon-α2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response

Furusyo, N., Murata, M., Ogawa, E., Toyoda, K., Ihara, T., Ikezaki, H., Hayashi, T., Koga, T., Kainuma, M. & Hayashi, J., May 1 2011, In : Journal of Antimicrobial Chemotherapy. 66, 5, p. 1127-1139 13 p., dkr034.

Research output: Contribution to journalArticle

Ribavirin
Chronic Hepatitis C
Interferons
Recurrence
Therapeutics
8 Citations (Scopus)

Treatment for eradication of Helicobacter pylori infection among chronic hepatitis C patients

Furusyo, N., Walaa, A. H., Eiraku, K., Toyoda, K., Ogawa, E., Ikezaki, H., Ihara, T., Hayashi, T., Kainuma, M., Murata, M. & Hayashi, J., Dec 1 2011, In : Gut and Liver. 5, 4, p. 447-453 7 p.

Research output: Contribution to journalArticle

Helicobacter Infections
Chronic Hepatitis C
Helicobacter pylori
Hepacivirus
Therapeutics
2010

Comparison of the effects of keishibukuryogan and atorvastatin on balloon injury-induced intimal thickening in rat carotid artery

Morimoto, Y., Shibata, Y., Ochiai, S., Ogino, F., Kainuma, M. & Mitsuma, T., Jan 1 2010, In : Journal of Traditional Medicines. 27, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Tunica Intima
Carotid Arteries
Cholesterol
Wounds and Injuries
Diet
9 Citations (Scopus)

Excellent superiority and specificity of COBAS TaqMan HCV assay in an early viral kinetic change during pegylated interferon alpha-2b plus ribavirin treatment

Ogawa, E., Furusyo, N., Toyoda, K., Taniai, H., Otaguro, S., Kainuma, M., Murata, M., Sawayama, Y. & Hayashi, J., Apr 16 2010, In : BMC Gastroenterology. 10, 38.

Research output: Contribution to journalArticle

Ribavirin
RNA
Genotype
Therapeutics
Antiviral Agents
39 Citations (Scopus)

Pegylated interferon α-2b plus ribavirin for older patients with chronic hepatitis C

Kainuma, M., Furusyo, N., Kajiwara, E., Takahashi, K., Nomura, H., Tanabe, Y., Satoh, T., Maruyama, T., Nakamuta, M., Kotoh, K., Azuma, K., Shimono, J., Shimoda, S. & Hayashi, J., Sep 21 2010, In : World Journal of Gastroenterology. 16, 35, p. 4400-4409 10 p.

Research output: Contribution to journalArticle

Ribavirin
Chronic Hepatitis C
Interferons
Genotype
Hepacivirus
2009
7 Citations (Scopus)

Protein-losing enteropathy during highly active antiretroviral therapy in a patient with AIDS-related disseminated Mycobacterial avium complex infection

Ogawa, E., Murata, M., Unno, M., Otaguro, S., Kainuma, M., Sawayama, Y., Furusyo, N., Yanai, S., Matsumoto, T. & Hayashi, J., Aug 2009, In : Journal of Infection and Chemotherapy. 15, 4, p. 252-256 5 p.

Research output: Contribution to journalArticle

Protein-Losing Enteropathies
Mycobacterium avium Complex
Highly Active Antiretroviral Therapy
Acquired Immunodeficiency Syndrome
Intestinal Lymphangiectasis
2008
23 Citations (Scopus)

Evidence-based efficacy of kampo formulas in a model of non alcoholic fatty liver

Fujimoto, M., Tsuneyama, K., Kainuma, M., Sekiya, N., Goto, H., Takano, Y., Terasawa, K., Selmi, C., Gershwin, M. E. & Shimada, Y., Mar 1 2008, In : Experimental Biology and Medicine. 233, 3, p. 328-337 10 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Kampo Medicine
pioglitazone
Liver
Fatty Liver
16 Citations (Scopus)

Intravenous immunoglobulin therapy for severe arthritis associated with human parvovirus B19 infection

Ogawa, E., Otaguro, S., Murata, M., Kainuma, M., Sawayama, Y., Furusyo, N. & Hayashi, J., Oct 2008, In : Journal of Infection and Chemotherapy. 14, 5, p. 377-382 6 p.

Research output: Contribution to journalArticle

Human Parvovirus B19
Parvoviridae Infections
Passive Immunization
Intravenous Immunoglobulins
Arthritis
2005
1 Citation (Scopus)

Changes of peripheral lymphocyte population in patients with chronic hepatitis C treated with herbal medicine (Maoto) and IFN-ß

Kainuma, M., Kogure, T., Sekiya, N., Mitsuma, T., Shimada, Y. & Terasawa, K., Jan 1 2005, In : Journal of Traditional Medicines. 22, 42403, p. 29-33 5 p.

Research output: Contribution to journalArticle

Herbal Medicine
Chronic Hepatitis C
Lymphocytes
Population
Flow Cytometry
2004
10 Citations (Scopus)

The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-β

Kainuma, M., Sakai, S., Sekiya, N., Mantani, N., Ogata, N., Shimada, Y. & Terasawa, K., Jan 2004, In : Phytomedicine. 11, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

Herbal Medicine
Chronic Hepatitis C
Interferons
Injections
Interleukins
2002
13 Citations (Scopus)

The efficacy of a herbal medicine (Mao-to) in combination with intravenous natural interferon-β for patients with chronic hepatitis C, genotype 1b and high viral load: A pilot study

Kainuma, M., Ogata, N., Kogure, T., Kohta, K., Hattori, N., Mitsuma, T. & Terasawa, K., Jul 2002, In : Phytomedicine. 9, 5, p. 365-372 8 p.

Research output: Contribution to journalArticle

Herbal Medicine
Chronic Hepatitis C
Viral Load
Interferons
Genotype