Comprehensive Clinical Oncology

Research Output 1992 2019

2015
7 Citations (Scopus)

Stereotactic body radiation therapy for primary lung cancers clinically diagnosed without pathological confirmation: a single-institution experience

Yoshitake, T., Nakamura, K., Shioyama, Y., Sasaki, T., Saiji, O., Shinoto, M., Terashima, K., Asai, K., Matsumoto, K., Matsuo, Y., Baba, S. & Honda, H., Jan 1 2015, In : International Journal of Clinical Oncology. 20, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Radiotherapy
Lung
Survival Rate
Radiation Pneumonitis
3 Citations (Scopus)

Successful combination chemotherapy for metastatic inflammatory myofibroblastic tumor: A case report

Inadomi, K., Kumagai, H., Takayoshi, K., ariyama, H., Kusaba, H., Nishie, A., Yamamoto, H., Takase, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Arita, S., Oda, Y., Akashi, K. & Baba, E., Nov 1 2015, In : Oncology Letters. 10, 5, p. 2981-2985 5 p.

Research output: Contribution to journalArticle

Combination Drug Therapy
Neoplasms
Cyclin-Dependent Kinase 4
Drug Therapy
Ifosfamide
1 Citation (Scopus)
Stem Cell Research
Neoplastic Stem Cells
Stem Cells
Population
Neoplasms

The possibility of definitive chemoradiotherapy for patients with resectable stage IIIA N2 non-small cell lung cancer

Sasaki, T., Seto, T., Saiji, O. & Yoshitake, T., Oct 20 2015, In : Japanese Journal of Lung Cancer. 55, 6, p. 982-985 4 p.

Research output: Contribution to journalReview article

Chemoradiotherapy
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Japan
Therapeutics
6 Citations (Scopus)

Treatment outcome of radiotherapy for localized primary ocular adnexal MALT lymphoma - Prognostic effect of the AJCC tumor-node-metastasis clinical staging system

Saiji, O., Nakamura, K., Shioyama, Y., Sasaki, T., Yamaguchi, T., Yoshitake, T., Terashima, K., Asai, K., Matsumoto, K. & Honda, H., Jan 1 2015, In : Anticancer Research. 35, 6, p. 3591-3597 7 p.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Radiotherapy
Neoplasm Metastasis
Disease-Free Survival
Neoplasms
1 Citation (Scopus)

Treatment planning comparison for carbon ion radiotherapy, proton therapy and intensity-modulated radiotherapy for spinal sarcoma

Matsumoto, K., Nakamura, K., Shioyama, Y., Sasaki, T., Saiji, O., Yamaguchi, T., Yoshitake, T., Asai, K., Kakiuchi, G. & Honda, H., Jul 1 2015, In : Anticancer Research. 35, 7, p. 4083-4090 8 p.

Research output: Contribution to journalArticle

Heavy Ion Radiotherapy
Proton Therapy
Intensity-Modulated Radiotherapy
Sarcoma
Spinal Cord
2016
13 Citations (Scopus)

Bi-cytopenia possibly induced by anti-PD-1 antibody for primary malignant melanoma of the esophagus A case report

Inadomi, K., Kumagai, H., Arita, S., Tsuruta, N., Takayoshi, K., Mishima, K., Ota, S. I., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Hiroshi, U., Yamamoto, H., ariyama, H., Kusaba, H., Niiro, H., Oda, Y., Akashi, K. & Baba, E., Jul 26 2016, In : Medicine (United States). 95, 29, e4283.

Research output: Contribution to journalArticle

Esophagus
Melanoma
Antibodies
Neoplasm Metastasis
Liver
5 Citations (Scopus)

Characteristics of smoking patients with lung cancer with emphysematous bullae

Iwama, E., Okamoto, I., Yabuuchi, H., Takayama, K., Harada, T., Matsuo, Y., Tokunaga, S., Baba, E. & Nakanishi, Y., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 9, p. 1586-1590 5 p.

Research output: Contribution to journalArticle

Blister
Lung Neoplasms
Smoking
Emphysema
Epidermal Growth Factor
2 Citations (Scopus)

Clinicopathological evaluation of pre-operative chemoradiotherapy with S-1 as a treatment for locally advanced oral squamous cell carcinoma

Kawano, S., Zheng, Y., Oobu, K., Matsubara, R., Goto, Y., Chikui, T., Yoshitake, T., Kiyoshima, T., Jinno, T., Maruse, Y., Mitate, E., kitamura, R., Tanaka, H., Toyoshima, T., Sugiura, T. & Nakamura, S., May 1 2016, In : Oncology Letters. 11, 5, p. 3369-3376 8 p.

Research output: Contribution to journalArticle

Chemoradiotherapy
Squamous Cell Carcinoma
Therapeutics
Radiotherapy
Survival Rate

Efficacy analysis of the aprepitant-combined antiemetic prophylaxis for non-round cell soft-tissue sarcoma patients received adriamycin and ifosfamide therapy

Kusaba, H., Kumagai, H., Inadomi, K., Matsunobu, T., Harimaya, K., Takayoshi, K., Arita, S., ariyama, H., Akashi, K. & Baba, E., Jan 1 2016, In : Medicine (United States). 95, 49, p. e5460

Research output: Contribution to journalArticle

aprepitant
Ifosfamide
Antiemetics
Sarcoma
Doxorubicin
1 Citation (Scopus)

Efficacy and safety analysis of chemotherapy for advanced colitis-associated colorectal cancer in Japan

Nio, K., Higashi, D., Kumagai, H., Arita, S., Shirakawa, T., Nakashima, K., Shibata, Y., Esaki, M., Manabe, T., Nagai, S., Ueki, T., Nakano, M., ariyama, H., Kusaba, H., Hirahashi, M., Oda, Y., Esaki, T., Mitsugi, K., Futami, K., Akashi, K. & 1 others, Baba, E., Jun 1 2016, In : Anti-Cancer Drugs. 27, 5, p. 457-463 7 p.

Research output: Contribution to journalArticle

Colitis
Colorectal Neoplasms
Japan
Safety
Drug Therapy
9 Citations (Scopus)

Efficacy and safety of TAS-102 in clinical practice of salvage chemotherapy for metastatic colorectal cancer

Arita, S., Shirakawa, T., Matsushita, Y., Shimokawa, H. K., Hirano, G., Makiyama, A., Shibata, Y., Tamura, S., Esaki, T., Mitsugi, K., ariyama, H., Kusaba, H., Akashi, K. & Baba, E., Apr 1 2016, In : Anticancer Research. 36, 4, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Safety
Drug Therapy
Febrile Neutropenia
Medical Oncology
14 Citations (Scopus)

Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

Kaneko, M., Iwase, I., Yamasaki, Y., Takai, T., Wu, Y., Kanemoto, S., Matsuhisa, K., Asada, R., Okuma, Y., Watanabe, T., Imaizumi, K. & Nomura, Y., Aug 3 2016, In : Scientific reports. 6, 30955.

Research output: Contribution to journalArticle

Gene Expression Profiling
Ligases
Ubiquitin
Endoplasmic Reticulum
Proteolysis
3 Citations (Scopus)

Immunosuppressant therapy successfully improved regorafenib-induced severe hepatic injury in a patient with metastatic gastrointestinal stromal tumor: A case report

Kuwayama, M., Uchino, K., Takayoshi, K., Komoda, M., Kohjima, M., Nakamuta, M., Momosaki, S., Kusaba, H., Akashi, K. & Baba, E., Jan 1 2016, In : Oncology Letters. 11, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Immunosuppressive Agents
Liver
Wounds and Injuries
Prednisolone
1 Citation (Scopus)

Intraluminal superior vena cava metastasis from adenosquamous carcinoma of the duodenum: A case report

Takayoshi, K., ariyama, H., Tamura, S., Yoda, S., Arita, T., Yamaguchi, T., Ozono, K., Yamamoto, H., Inadomi, K., Kumagai, H., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Arita, S., Kusaba, H., Odashiro, K., Oda, Y., Akashi, K. & 1 others, Baba, E., Jan 1 2016, In : Oncology Letters. 11, 1, p. 605-609 5 p.

Research output: Contribution to journalArticle

Adenosquamous Carcinoma
Superior Vena Cava
Duodenum
Neoplasm Metastasis
oxaliplatin
21 Citations (Scopus)

Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors

Murahashi, M., Hijikata, Y., Yamada, K., Tanaka, Y., Kishimoto, J., Inoue, H., Marumoto, T., Takahashi, A., Okazaki, T., Takeda, K., Hirakawa, M., Fujii, H., Okano, S., Morita, M., Baba, E., Mizumoto, K., Maehara, Y., Tanaka, M., Akashi, K., Nakanishi, Y. & 5 others, Yoshida, K., Tsunoda, T., Tamura, K., Nakamura, Y. & Tani, K., May 1 2016, In : Clinical Immunology. 166-167, p. 48-58 11 p.

Research output: Contribution to journalArticle

Clinical Trials, Phase I
Cancer Vaccines
Subunit Vaccines
Neoplasm Antigens
Cyclophosphamide
14 Citations (Scopus)

Phase II trial of weekly nab-paclitaxel for previously treated advanced non–small cell lung cancer: Kumamoto thoracic oncology study group (KTOSG) trial 1301

Sakata, S., Saeki, S., Okamoto, I., Otsubo, K., Komiya, K., Morinaga, R., Yoneshima, Y., Koga, Y., Enokizu, A., Kishi, H., Hirosako, S., Yamaguchi, E., Aragane, N., Fujii, S., Harada, T., Iwama, E., Semba, H., Nakanishi, Y. & Kohrogi, H., Sep 1 2016, In : Lung Cancer. 99, p. 41-45 5 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Thorax
docetaxel
Confidence Intervals
Febrile Neutropenia

Prognostic significance of a minute amount of ascites during chemoradiotherapy for locally advanced pancreatic cancer

Shinoto, M., Nakamura, K., Shioyama, Y., Sasaki, T., Nishie, A., Asayama, Y., Saiji, O., Yoshitake, T., Terashima, K., Asai, K., Matsumoto, K. & Honda, H., Apr 1 2016, In : Anticancer research. 36, 4, p. 1879-1884 6 p.

Research output: Contribution to journalArticle

Chemoradiotherapy
Pancreatic Neoplasms
Ascites
Survival
Tomography
50 Citations (Scopus)

Randomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G)

Yamazaki, K., Nagase, M., Tamagawa, H., Ueda, S., Tamura, T., Murata, K., Eguchi Nakajima, T., Baba, E., Tsuda, M., Moriwaki, T., Esaki, T., Tsuji, Y., Muro, K., Taira, K., Denda, T., Funai, S., Shinozaki, K., Yamashita, H., Sugimoto, N., Okuno, T. & 28 others, Nishina, T., Umeki, M., Kurimoto, T., Takayama, T., Tsuji, A., Yoshida, M., Hosokawa, A., Shibata, Y., Suyama, K., Okabe, M., Suzuki, K., Seki, N., Kawakami, K., Sato, M., Fujikawa, K., Hirashima, T., Shimura, T., Taku, K., Otsuji, T., Tamura, F., Shinozaki, E., Nakashima, K., Hara, H., Tsushima, T., Ando, M., Morita, S., Boku, N. & Hyodo, I., Aug 1 2016, In : Annals of Oncology. 27, 8, p. 1539-1546 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Disease-Free Survival
Quality of Life
Confidence Intervals
Therapeutics
2 Citations (Scopus)

Retrospective analysis of cardiovascular diseases related to chemotherapies for advanced solid tumor patients

Shirakawa, T., Nakano, M., Nio, K., Tamura, S., Komoda, M., Kumagai, H., Uchino, K., Odashiro, K., Arita, S., Shibata, Y., ariyama, H., Kusaba, H., Akashi, K. & Baba, E., Sep 1 2016, In : Anti-Cancer Drugs. 27, 9, p. 891-898 8 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Drug Therapy
Neoplasms
Heart Diseases
Venous Thrombosis
17 Citations (Scopus)

Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumors

Tamura, K., Hashimoto, J., Tanabe, Y., Kodaira, M., Yonemori, K., Seto, T., Hirai, F., Arita, S., Toyokawa, G., Chen, L., Yamamoto, H., Kawata, T., Lindemann, J. & Esaki, T., Apr 1 2016, In : Cancer chemotherapy and pharmacology. 77, 4, p. 787-795 9 p.

Research output: Contribution to journalArticle

Tumors
Safety
Neoplasms
Pharmacokinetics
Appointments and Schedules
23 Citations (Scopus)

The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)

Tsuchihashi, K., Okazaki, S., Ohmura, M., Ishikawa, M., Sampetrean, O., Onishi, N., Wakimoto, H., Yoshikawa, M., Seishima, R., Iwasaki, Y., Morikawa, T., Abe, S., Takao, A., Shimizu, M., Masuko, T., Nagane, M., Furnari, F. B., Akiyama, T., Suematsu, M., Baba, E. & 3 others, Akashi, K., Saya, H. & Nagano, O., May 15 2016, In : Cancer Research. 76, 10, p. 2954-2963 10 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Epidermal Growth Factor Receptor
Glioma
Cystine
Glutamic Acid
2017
2 Citations (Scopus)

Anti-epidermal growth factor receptor antibody readministration in chemorefractory metastatic colorectal cancer

Kajitani, T., Makiyama, A., Arita, S., Shimokawa, H., Oda, H., Shirakawa, T., Baba, E. & Esaki, T., Nov 1 2017, In : Anticancer Research. 37, 11, p. 6459-6468 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Colorectal Neoplasms
Antibodies
Anti-Idiotypic Antibodies
irinotecan
7 Citations (Scopus)

A phase II study of 5-fluorouracil/L-leucovorin/oxaliplatin (mFOLFOX6) in Japanese patients with metastatic or unresectable small bowel adenocarcinoma

Horimatsu, T., Nakayama, N., Moriwaki, T., Hirashima, Y., Fujita, M., Asayama, M., Moriyama, I., Nakashima, K., Baba, E., Kitamura, H., Tamura, T., Hosokawa, A., Yoshimura, K. & Muto, M., Oct 1 2017, In : International Journal of Clinical Oncology. 22, 5, p. 905-912 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Leucovorin
Fluorouracil
Adenocarcinoma
Disease-Free Survival
4 Citations (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., Nov 1 2017, In : Lung Cancer. 113, p. 72-78 7 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
1 Citation (Scopus)

Chronic myelomonocytic leukemia blast crisis in a patient with advanced non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Ogata, H., Okamoto, I., Yoshimoto, G., Obara, T., Ijichi, K., Iwama, E., Harada, T., Akashi, K. & Nakanishi, Y., Mar 1 2017, In : Respiratory Investigation. 55, 2, p. 181-183 3 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
erbB-1 Genes
Blast Crisis
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
2 Citations (Scopus)

Early tumor shrinkage indicates a favorable response to bevacizumab-based first-line chemotherapy for metastatic colorectal cancer

Ito, M., Kusaba, H., Mukaide, S., Kishimoto, J., Shimokawa, H., Tamura, S., Makiyama, A., Hirano, G., Oda, H., Shirakawa, T., Komoda, M., Uchino, K., Tanaka, R., Mitsugi, K., Esaki, T., Arita, S., ariyama, H., Akashi, K. & Baba, E., Jan 1 2017, In : Anti-cancer drugs. 28, 10, p. 1166-1173 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Drug Therapy
Survival
Neoplasms
Growth Factor Receptors

Interleukin-22 attenuates double-stranded RNA-induced upregulation of PD-L1 in airway epithelial cells via a STAT3-dependent mechanism

Seki, N., Kan-o, K., Matsumoto, K., Fukuyama, S., Hamano, S., Tonai, K., ota, K., Inoue, H. & Nakanishi, Y., Dec 9 2017, In : Biochemical and Biophysical Research Communications. 494, 1-2, p. 242-248 7 p.

Research output: Contribution to journalArticle

Double-Stranded RNA
Up-Regulation
Epithelial Cells
Poly C
Viruses
1 Citation (Scopus)

Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Nov 1 2017, In : Medicine (United States). 96, 44, e8470.

Research output: Contribution to journalArticle

Alveolar Soft Part Sarcoma
Tongue
Articulation Disorders
Lung
Ifosfamide

Metastatic esophageal cancer presenting as shock by injury of vagus nerve mimicking baroreceptor reflex: A case report

Tsuchihashi, K., Yoshihiro, T., Aikawa, T., Nio, K., Takayoshi, K., Yokoyama, T., Fukata, M., Arita, S., ariyama, H., Shimizu, Y., Yoshida, Y., torisu, T., Esaki, M., Odashiro, K., Kusaba, H., Akashi, K. & Baba, E., Dec 1 2017, In : Medicine (United States). 96, 49, e8987.

Research output: Contribution to journalArticle

Vagus Nerve Injuries
Baroreflex
Esophageal Neoplasms
Vagus Nerve
Shock
22 Citations (Scopus)

Monitoring of somatic mutations in circulating cell-free DNA by digital PCR and next-generation sequencing during afatinib treatment in patients with lung adenocarcinoma positive for EGFR activating mutations

Iwama, E., Sakai, K., Azuma, K., Harada, T., Harada, D., Nosaki, K., Hotta, K., Ohyanagi, F., Kurata, T., Fukuhara, T., Akamatsu, H., Goto, K., Shimose, T., Kishimoto, J., Nakanishi, Y., Nishio, K. & Okamoto, I., Jan 1 2017, In : Annals of Oncology. 28, 1, p. 136-141 6 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Polymerase Chain Reaction
Mutation
DNA
Alleles
16 Citations (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., Jun 1 2017, In : Lung Cancer. 108, p. 75-82 8 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Alleles
Mutation
Protein-Tyrosine Kinases

Regorafenib-induced retinal and gastrointestinal hemorrhage in a metastatic colorectal cancer patient with liver dysfunction

Tsuchihashi, K., Shimokawa, H., Takayoshi, K., Nio, K., Aikawa, T., Matsushita, Y., Wada, I., Arita, S., ariyama, H., Kusaba, H., Sonoda, K., Akashi, K. & Baba, E., Oct 1 2017, In : Medicine (United States). 96, 42, e8285.

Research output: Contribution to journalArticle

Retinal Hemorrhage
Gastrointestinal Hemorrhage
Liver Diseases
Colorectal Neoplasms
Hemorrhage
6 Citations (Scopus)

Suggestion of added value by bevacizumab to chemotherapy in patients with unresectable or recurrent small bowel cancer

Takayoshi, K., Kusaba, H., Uenomachi, M., Mitsugi, K., Makiyama, C., Makiyama, A., Uchino, K., Shirakawa, T., Shibata, Y., Shinohara, Y., Inadomi, K., Tsuchihashi, K., Arita, S., ariyama, H., Esaki, T., Akashi, K. & Baba, E., Aug 1 2017, In : Cancer Chemotherapy and Pharmacology. 80, 2, p. 333-342 10 p.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Chemotherapy
Drug Therapy
Adenocarcinoma
oxaliplatin

Systemic chemotherapy with pronounced efficacy and neutropenia in a granulocyte-colony stimulating factor-producingadvanced gastric neuroendocrine carcinoma

Tsuruta, N., Takayoshi, K., Arita, S., Aikawa, T., ariyama, H., Kusaba, H., Ouchida, K., Nagai, E., Kouhashi, K., Hirahashi, M., Inadomi, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Jan 1 2017, In : Oncology Letters. 14, 2, p. 1500-1504 5 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Granulocyte Colony-Stimulating Factor
Neutropenia
Stomach
Drug Therapy
1 Citation (Scopus)
2018
6 Citations (Scopus)

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Hiroshi, U., ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., Oct 1 2018, In : Cancer Science. 109, 10, p. 3032-3042 11 p.

Research output: Contribution to journalArticle

Th1 Cells
Melanoma
T-Lymphocytes
Antibodies
Phenotype
1 Citation (Scopus)

Alkaline Phosphatase-Catalyzed Amplification of a Fluorescence Signal for Flow Cytometry

Nobori, T., Tosaka, K., Kawamura, A., Joichi, T., Kamino, K., Kishimura, A., Baba, E., Mori, T. & Katayama, Y., Jan 16 2018, In : Analytical Chemistry. 90, 2, p. 1059-1062 4 p.

Research output: Contribution to journalArticle

Flow cytometry
Amplification
Alkaline Phosphatase
Fluorescence
Fluorophores

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., ariyama, H., Esaki, T., Akashi, K. & Baba, E., Jun 1 2018, In : Medicine (United States). 97, 25, e11042.

Research output: Contribution to journalArticle

fosaprepitant
Dexamethasone
Antiemetics
Drug Therapy
Neoplasms

Association of nephrotoxicity during platinum-etoposide doublet therapy with UGT1A1 polymorphisms in small cell lung cancer patients

Anai, S., Iwama, E., Yoneshima, Y., Otsubo, K., Tanaka, K., Nakanishi, Y. & Okamoto, I., Dec 1 2018, In : Lung Cancer. 126, p. 156-161 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Etoposide
Platinum
Alleles
irinotecan
1 Citation (Scopus)

Combined therapy with epidermal growth factor receptor tyrosine kinase inhibitors for non–small cell lung cancer

Iwama, E., Nakanishi, Y. & Okamoto, I., Mar 4 2018, In : Expert Review of Anticancer Therapy. 18, 3, p. 267-276 10 p.

Research output: Contribution to journalReview article

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Therapeutics
1 Citation (Scopus)

Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade

Tanaka, K., Yanagihara, T., Ikematsu, Y., Inoue, H., ota, K., Kashiwagi, E., Suzuki, K., Hamada, N., takeuchi, A., Tatsugami, K., Eto, M., Ijichi, K., Oda, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., Jul 17 2018, In : Oncotarget. 9, 55, p. 30587-30593 7 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage Fluid
Pleural Effusion
Pneumonia
Clone Cells
T-Cell Antigen Receptor
1 Citation (Scopus)

E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Tamura, S., Isobe, T., ariyama, H., Nakano, M., Kikushige, Y., Takaishi, S., Kusaba, H., Takenaka, K., Ueki, T., Nakamura, M., Akashi, K. & Baba, E., Aug 1 2018, In : Oncology reports. 40, 2, p. 693-703 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Cadherins
Colorectal Neoplasms
Cyclin D1
Embryonic Stem Cells
1 Citation (Scopus)

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 1 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journalArticle

Glutamate Receptors
Epidermal Growth Factor Receptor
Glioma
Glutamic Acid
Epidermal Growth Factor

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., ariyama, H., Mitsugi, K., Makiyama, A., Uchino, K., Esaki, T., Tsuruta, N., Hanamura, F., Yamaguchi, K., Okumura, Y., Sagara, K., Takayoshi, K., Nio, K., Tsuchihashi, K., Tamura, S., Shimokawa, H., Arita, S., Miyawaki, K. & 3 others, Kusaba, H., Akashi, K. & Baba, E., Nov 1 2018, In : Cancer Science. 109, 11, p. 3461-3470 10 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Epithelial-Mesenchymal Transition
Ascites
Neoplasms
Transforming Growth Factor beta
6 Citations (Scopus)

Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing

Iwama, E., Sakai, K., Azuma, K., Harada, D., Nosaki, K., Hotta, K., Nishio, M., Kurata, T., Fukuhara, T., Akamatsu, H., Goto, K., Shimose, T., Kishimoto, J., Nakanishi, Y., Nishio, K. & Okamoto, I., Dec 1 2018, In : Cancer Science. 109, 12, p. 3921-3933 13 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Polymerase Chain Reaction
Mutation
Neoplasms
1 Citation (Scopus)

Expression of brain-derived neurotrophic factor and its receptor TrkB is associated with poor prognosis and a malignant phenotype in small cell lung cancer

Kimura, S., Harada, T., Ijichi, K., Tanaka, K., Liu, R., Shibahara, D., Kawano, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., Jun 1 2018, In : Lung Cancer. 120, p. 98-107 10 p.

Research output: Contribution to journalArticle

trkB Receptor
Brain-Derived Neurotrophic Factor
Small Cell Lung Carcinoma
Phenotype
Non-Small Cell Lung Carcinoma
1 Citation (Scopus)

First-line chemotherapy with S-1 alone or S-1 plus cisplatin for elderly patients with advanced gastric cancer: a multicenter propensity score matched study

Makiyama, A., Kunieda, K., Noguchi, M., Kajiwara, T., Tamura, T., Takeda, K., Sugiyama, J., Minashi, K., Moriwaki, T., Sugimoto, N., Nagase, M., Negoro, Y., Tsuda, T., Shimodaira, H., Okano, N., Tsuji, A., Sakai, D., Yanagihara, K., Ueda, S., Tamura, S. & 15 others, Otsu, S., Honda, T., Matsushita, Y., Okuno, T., Kashiwada, T., Nozaki, A., Ebi, M., Okuda, H., Shimokawa, M., Hironaka, S., Hyodo, I., Baba, E., Boku, N., Muro, K. & Esaki, T., Sep 1 2018, In : Gastric Cancer. 21, 5, p. 792-801 10 p.

Research output: Contribution to journalArticle

Propensity Score
Cisplatin
Stomach Neoplasms
Drug Therapy
Geriatric Assessment
5 Citations (Scopus)

Intrinsic and Extrinsic Regulation of PD-L2 Expression in Oncogene-Driven Non–Small Cell Lung Cancer

Shibahara, D., Tanaka, K., Iwama, E., Kubo, N., ota, K., Azuma, K., Harada, T., Fujita, J., Nakanishi, Y. & Okamoto, I., Jul 1 2018, In : Journal of Thoracic Oncology. 13, 7, p. 926-937 12 p.

Research output: Contribution to journalArticle

Oncogenes
Non-Small Cell Lung Carcinoma
Cell Death
Ligands
STAT3 Transcription Factor
3 Citations (Scopus)

Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

Makiyama, A., Arimizu, K., Hirano, G., Makiyama, C., Matsushita, Y., Shirakawa, T., Ohmura, H., Komoda, M., Uchino, K., Inadomi, K., Arita, S., ariyama, H., Kusaba, H., Shinohara, Y., Kuwayama, M., Kajitani, T., Oda, H., Esaki, T., Akashi, K. & Baba, E., May 1 2018, In : Gastric Cancer. 21, 3, p. 464-472 9 p.

Research output: Contribution to journalArticle

irinotecan
Stomach Neoplasms
Salvage Therapy
Therapeutics
Survival