Department of Advanced Medical Initiatives

Research Output 1980 2020

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1980

Treatment of collagen diseases - A questionnaire survey in Japan

Nobunaga, M. & Shiokawa, Y., Jan 1 1980, In : Ryumachi. 20, 3, 1 p.

Research output: Contribution to journalArticle

Collagen Diseases
Dermatomyositis
Systemic Scleroderma
Systemic Lupus Erythematosus
Rheumatoid Arthritis
1983
136 Citations (Scopus)

Morphology of Gastric Microcirculation in Cirrhosis

Hashizume, M., Tanaka, K. & Inokuchi, K., 1983, In : Hepatology. 3, 6, p. 1008-1012 5 p.

Research output: Contribution to journalArticle

Microcirculation
Stomach
Arterioles
Fibrosis
Arteriovenous Anastomosis
1984
42 Citations (Scopus)

Exclusion of nonisolated splenic vein in distal splenorenal shunt for prevention of portal malcirculation

Inokuchi, K., Beppu, K., Koyanagi, N., Nagamine, K., Hashizume, M. & Sugimachi, K., Jan 1 1984, In : Annals of surgery. 200, 6, p. 711-717 7 p.

Research output: Contribution to journalArticle

Surgical Splenorenal Shunt
Splenic Vein
Ligation
Theft
Flowmeters
26 Citations (Scopus)

Fifteen years' experience with left gastric venous caval shunt for esophageal varices

Inokuchi, K., Beppu, K., Koyanagi, N., Nagamine, K., Hashizume, M., Iwanaga, T. & Sugimachi, K., Oct 1 1984, In : World journal of surgery. 8, 5, p. 716-721 6 p.

Research output: Contribution to journalArticle

Venae Cavae
Esophageal and Gastric Varices
Stomach
Portal Hypertension
Postoperative Period
2 Citations (Scopus)

Long-term oral antiarrhythmic therapy with aprindine: Effects on cardiac function and adverse effects

Tsutsui, H., Araki, H., Nagata, Y. & Nakamura, M., Dec 1 1984, In : Clinical Therapeutics. 6, 6, p. 770-777 8 p.

Research output: Contribution to journalArticle

Aprindine
Signs and Symptoms
Cardiac Arrhythmias
Heart Diseases
Therapeutics
13 Citations (Scopus)

The natural history of nonalcoholic cirrhosis

Hashizume, M., Inokuchi, K., Beppu, K., Koyanagi, N., Nagamine, K., Sugimachi, K. & Hirose, S., Oct 1 1984, In : Gastroenterologia Japonica. 19, 5, p. 430-435 6 p.

Research output: Contribution to journalArticle

Varicose Veins
Fibrosis
Hepatocellular Carcinoma
Hemorrhage
Esophageal and Gastric Varices
1985
4 Citations (Scopus)

Coronary Spasm and Allergy Retrospective Study of the Incidence of Allergic history in Patients with Variant Angina

Tsutsui, H., Tomoike, H., Araki, H. & Nakamura, M., Jan 1 1985, In : japanese heart journal. 26, 2, p. 191-195 5 p.

Research output: Contribution to journalArticle

Spasm
Hypersensitivity
Retrospective Studies
History
Incidence
2 Citations (Scopus)

Hyperdynamic circulation in the left gastric venous area in patients with portal hypertension: Angiological assessment

Koyanagi, N., Inokuchi, K., Beppu, K., Nagamine, K., Hashizume, M. & Sugimachi, K., Mar 1 1985, In : The Japanese Journal of Surgery. 15, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

Portal Hypertension
Stomach
Veins
Varicose Veins
Portal Vein
15 Citations (Scopus)

The role of prostacyclin in patients with portal hypertension

Hashizume, M., Inokuchi, K. & Tanaka, K., Apr 1985, In : Liver. 5, 2, p. 89-93 5 p.

Research output: Contribution to journalArticle

Portal Hypertension
Epoprostenol
Portal Pressure
Portal Vein
Collateral Circulation
1986
9 Citations (Scopus)

Patterns of pannus growth of the expanded polytetrafluoroethylene vascular graft with special attention to the intimal hyperplasia formation

Kuwano, H., Hashizume, M., Yang, Y., Kholoussy, A. M. & Matsumoto, T., Dec 1 1986, In : American Surgeon. 52, 12, p. 663-666 4 p.

Research output: Contribution to journalArticle

Tunica Intima
Polytetrafluoroethylene
Hyperplasia
Blood Vessels
Transplants
1987
10 Citations (Scopus)

Argon laser angioplasty with a laser probe

Yang, Y., Hashizume, M., Arbutina, D., Milewski, L. F., DuPree, J. & Matsumoto, T., Jan 1 1987, In : Journal of Vascular Surgery. 6, 1, p. 60-65 6 p.

Research output: Contribution to journalArticle

Laser Angioplasty
Argon
Lasers
Thrombosis
Arteries
6 Citations (Scopus)

Direct vision valvulotomy for nonreversed vein graft

Matsumoto, T., Yang, Y. & Hashizume, M., Jan 1 1987, In : Surgery Gynecology and Obstetrics. 165, 2, p. 181-182 2 p.

Research output: Contribution to journalArticle

Angioscopes
Veins
Transplants
9 Citations (Scopus)

Direct vision valvulotomy in in situ venous bypass

Matsumoto, T., Hashizume, M., Yang, Y., Milewski, L. & Naide, D., Dec 1 1987, In : Surgery Gynecology and Obstetrics. 165, 4, p. 362-364 3 p.

Research output: Contribution to journalArticle

Angioscopes
Angioscopy
Lacerations
Veins
Communication
23 Citations (Scopus)

Intimal response of saphenous vein to intraluminal trauma by simulated angioscopic insertion

Hashizume, M., Yang, Y., Galt, S., Murthy, S. N. S. & Matsumoto, T., Jan 1 1987, In : Journal of Vascular Surgery. 5, 6, p. 862-868 7 p.

Research output: Contribution to journalArticle

Tunica Intima
Saphenous Vein
Veins
Wounds and Injuries
Epoprostenol
2 Citations (Scopus)

Ultrasonic duplex system to facilitate assessment of portal blood flow velocity

Iwanaga, T., Iso, Y., Hashizume, M., Koyanagi, N., Kitano, S. & Sugimachi, K., Jan 1 1987, In : European Surgical Research. 19, 3, p. 178-184 7 p.

Research output: Contribution to journalArticle

Blood Flow Velocity
Ultrasonics
Ethiodized Oil
Portal Vein
Blood Volume
1988
4 Citations (Scopus)

An ultrasonic duplex system facilitates detection of portal hemodynamic changes following selective shunts for esophageal varices

Iwanaga, T., Hashizume, M., Koyanagi, N., Kitano, S., Sugimachi, K. & Inokuchi, K., Jan 1 1988, In : Hepato-gastroenterology. 35, 2, p. 73-77 5 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Ultrasonics
Hemodynamics
Surgical Splenorenal Shunt
Portal Vein
8 Citations (Scopus)

Intraoperative hemostasis and wound healing in intestinalanastomoses using the ILA stapling device

Berman, S., Hashizume, M., Yang, Y., DuPree, J. & Matsumoto, T., Mar 1988, In : The American Journal of Surgery. 155, 3, p. 520-525 6 p.

Research output: Contribution to journalArticle

Hemostasis
Wound Healing
Microvessels
Silicone Elastomers
Equipment and Supplies

Percutaneous Transhepatic Portography and the Treatment of Esophagogastric Varices

Hashizume, M., Kitano, S., Wada, H., Tanoue, K. & Sugimachi, K., Feb 1 1988, In : the japanese journal of gastroenterological surgery. 23, 4, p. 985-989 5 p.

Research output: Contribution to journalArticle

Portography
Esophageal and Gastric Varices
Varicose Veins
Sclerotherapy
Blood Vessels
11 Citations (Scopus)

Temporary deterioration of pulmonary functions after injection sclerotherapy for cirrhotic patients with esophageal varices

Kitano, S., Iso, Y., Yamaga, H., Hashizume, M., Wada, H. & Sugimachi, K., Jan 1 1988, In : European Surgical Research. 20, 5-6, p. 298-303 6 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Lung
Injections
Closing Volume
112 Citations (Scopus)

Three‐dimensional view of the vascular structure of the lower esophagus in clinical portal hypertension

Hashizume, M., Kitano, S., Sugimachi, K. & Sueishi, K., Jan 1 1988, In : Hepatology. 8, 6, p. 1482-1487 6 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Portal Hypertension
Esophagus
Blood Vessels
Veins
33 Citations (Scopus)

Trial of sclerosing agents in patients with oesophageal varices

Kitano, S., Iso, Y., Yamaga, H., Hashizume, M., Higashi, H. & Sugimachi, K., Jan 1 1988, In : British Journal of Surgery. 75, 8, p. 751-753 3 p.

Research output: Contribution to journalArticle

Sodium Tetradecyl Sulfate
Sclerosing Solutions
Esophageal and Gastric Varices
Ethanolamine
Sclerotherapy
1989
34 Citations (Scopus)

Angioarchitectural Classification of Esophageal Varices and Paraesophageal Veins in Selective Left Gastric Venography

Hashizume, M., Kitano, S., Yamaga, H., Higashi, H. & Sugimachi, K., Aug 1989, In : Archives of Surgery. 124, 8, p. 961-966 6 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Phlebography
Veins
Stomach
Viscera
18 Citations (Scopus)

A prospective randomized trial of schedules for sclerosing esophageal varices. 1- versus 2-week intervals

Higashi, H., Kitano, S., Hashizume, M., Yamaga, H. & Sugimachi, K., Jan 1 1989, In : Hepato-gastroenterology. 36, 5, p. 337-340 4 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Appointments and Schedules
Sclerotherapy
Sclerosing Solutions
Varicose Veins
2 Citations (Scopus)

Endoscopic injection sclerotherapy: Variants of sclerotherapy technique

Kitano, S., Hashizume, M., Yamaga, H., Wada, H. & Sugimachi, K., Jan 1 1989, In : Journal of Gastroenterology and Hepatology. 4, SUPPL. 1, p. 171-172 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Endothelium-fibrinolysis system interaction

Sueishi, K., Yasunaga, C., Nakashima, Y., Tsutsui, H. & Ishii, Y., Dec 1 1989, In : Acta Haematologica Japonica. 52, 8, p. 1350-1358 9 p.

Research output: Contribution to journalArticle

Pathologic Neovascularization
Vascular Endothelium
Fibrinolysis
Endothelium
In Vitro Techniques
38 Citations (Scopus)

Human thrombin plus 5 per cent ethanolamine oleate injected to sclerose oesophageal varices: A prospective randomized trial

Kitano, S., Hashizume, M., Yamaga, H., Wada, H., Iso, Y., Iwanaga, T. & Sugimachi, K., Jul 1989, In : British Journal of Surgery. 76, 7, p. 715-718 4 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Sclerosis
Thrombin
Sclerotherapy
Injections
6 Citations (Scopus)

Morphological and hemodynamic changes of the lung after injection of 5% ethanolamine oleate into dogs

Iso, Y., Kitano, S., Iwanaga, T., Hashizume, M. & Sugimachi, K., Jan 1 1989, In : European Surgical Research. 21, 3-4, p. 175-183 9 p.

Research output: Contribution to journalArticle

Hemodynamics
Dogs
Lung
Injections
Sclerosing Solutions
2 Citations (Scopus)

Platelet aggregability after endoscopic intravariceal injection of 5 per cent ethanolamine oleate into oesophageal varices

Yamaga, H., Hashizume, M., Kitano, S., Higashi, H. & Sugimachi, K., Sep 1989, In : British Journal of Surgery. 76, 9, p. 939-942 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Blood Platelets
Injections
Thromboxane A2
13 Citations (Scopus)
Tunica Intima
Veins
Electrons
Transplants
Endothelial Cells
2 Citations (Scopus)

Vascular architecture of the lower oesophagus in portal hypertension

Hashizume, M., Kitano, S., Yamaga, H., Wada, H. & Sugimachi, K., Jan 1 1989, In : Journal of Gastroenterology and Hepatology. 4, SUPPL. 1, p. 201-203 3 p.

Research output: Contribution to journalArticle

1990

A case of acyclovir-resistant herpes simplex encephalitis improved dramatically by vidarabine (Ara-A)

Ohnaka, K., Kurata, T., Miyake, T., Sasagasako, N. & Ishimoto, S., Jan 1 1990, In : Japanese Journal of National Medical Services. 44, 7, p. 728-732 5 p.

Research output: Contribution to journalArticle

Vidarabine
Herpes Simplex Encephalitis
Acyclovir
Cerebrospinal Fluid
Muscle Rigidity
1 Citation (Scopus)

A case of hypopituitarism associated with empty sella and agenesis of corpus callosum, a variant form of septo-optic-pituitary dysplasia

Fukutomi, T., Masakado, M., Takayanagi, R., Ohnaka, K., Sekiya, K., Haji, M., Ohasi, M. & Nawata, H., Dec 1990, In : Fukuoka igaku zasshi = Hukuoka acta medica. 81, 12, p. 396-401 6 p.

Research output: Contribution to journalArticle

Septo-Optic Dysplasia
Agenesis of Corpus Callosum
Hypopituitarism
Pituitary Function Tests
Septum Pellucidum
53 Citations (Scopus)

Alterations of elastic architecture in human aortic dissecting aneurysm

Nakashima, Y., Shiokawa, Y. & Sueishi, K., Jan 1 1990, In : Laboratory Investigation. 62, 6, p. 751-760 10 p.

Research output: Contribution to journalArticle

Dissecting Aneurysm
Aortic Aneurysm
Elastin
formic acid
Necrosis
130 Citations (Scopus)

Endoscopic classification of gastric varices

Hashizume, M., Kitano, S., Yamaga, H., Koyanagi, N. & Sugimachi, K., Jan 1 1990, In : Gastrointestinal endoscopy. 36, 3, p. 276-280 5 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Color
Cardia
Varicose Veins
Endoscopy

Endoscopic markers of impending varceal hemorrhage: Correlation with the pressure in the varices

Beppu, K. & Hashizume, M., Jan 1990, In : Hepatology. 11, 1, p. 147-148 2 p.

Research output: Contribution to journalArticle

Varicose Veins
Hemorrhage
Pressure
Ascites
Color
166 Citations (Scopus)

Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells

Yamauchi, T., Ohnaka, K., Takayanagi, R., Umeda, F. & Nawata, H., Jul 2 1990, In : FEBS Letters. 267, 1, p. 16-18 3 p.

Research output: Contribution to journalArticle

Endothelial cells
Endothelin-1
Endothelial Cells
Glucose
Aldehyde Reductase
6 Citations (Scopus)

Eradication of oesophageal varices recurring after portal non‐decompressive surgery by injection sclerotherapy

Hashizume, M., Kitano, S., Yamaga, H., Wada, H. & Sugimachi, K., Aug 1990, In : British Journal of Surgery. 77, 8, p. 940-943 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Injections
Hemorrhage
Esophageal Stenosis
18 Citations (Scopus)

Hemodynamic and morphological changes in the dog kidney after injection of 5% ethanolamine oleate into the superior vena cava

Wada, H., Hashizume, M., Yamaga, H., Kitano, S. & Sugimachi, K., Jan 1 1990, In : European Surgical Research. 22, 2, p. 63-70 8 p.

Research output: Contribution to journalArticle

Superior Vena Cava
Renal Circulation
Hemodynamics
Dogs
Kidney
4 Citations (Scopus)

Heterogeneous distribution of a diffusional tracer in the aortic wall of normal and atherosclerotic rabbits

Tsutsui, H., Tomoike, H. & Nakamura, M., Jan 1 1990, In : Circulation research. 67, 2, p. 368-375 8 p.

Research output: Contribution to journalArticle

Thoracic Aorta
Tunica Intima
Radioactivity
Antipyrine
Abdominal Aorta
6 Citations (Scopus)

Hypercoagulopathy after repeated injection of 5% ethanolamine oleate to sclerose esophageal varices

Hashizume, M., Yamaga, H., Kitano, S. & Sugimachi, K., Dec 1 1990, In : Hepato-gastroenterology. 37, 6, p. 565-568 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Sclerosis
Injections
Latex
103 Citations (Scopus)

Identification and characterization of endothelin converting activity in cultured bovine endothelial cells

Ohnaka, K., Takayanagi, R., Yamauchi, T., Okazaki, H., Ohashi, M., Umeda, F. & Nawata, H., May 16 1990, In : Biochemical and Biophysical Research Communications. 168, 3, p. 1128-1136 9 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Endothelin-1
Endothelial Cells
Egtazic Acid

Mucosal denudation of the lower esophagus for prevention of recurrence of varices

Kitano, S., Wada, H., Tanoue, K., Hashizume, M. & Sugimachi, K., Apr 1 1990, In : Nippon rinsho. Japanese journal of clinical medicine. 48, 4, p. 770-773 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Myocardial protection by retrograde cardioplegia in arterial switch operation

Yonenaga, K., Yasui, H., Kado, H., Nakamura, Y., Shiokawa, Y., Yamamoto, T. & Miyamoto, K., Aug 1990, In : The Annals of Thoracic Surgery. 50, 2, p. 238-242 5 p.

Research output: Contribution to journalArticle

Induced Heart Arrest
Coronary Sinus
Perfusion
Cardioplegic Solutions
Hemodynamics
19 Citations (Scopus)

Primary repair for complete atrioventricular canal: Recommendation for early primary repair

Yasui, H., Nakamura, Y., Kado, H., Yonenaga, K., Shiokawa, Y., Fusazaki, N., Sunagawa, H. & Tokunaga, K., Jan 1 1990, In : Journal of Cardiovascular Surgery. 31, 4, p. 498-504 7 p.

Research output: Contribution to journalArticle

Heart Septal Defects
Pulmonary Circulation
Tricuspid Valve
Age Factors
Mitral Valve Insufficiency
8 Citations (Scopus)
Adrenergic Receptors
Lysergic Acid Diethylamide
Aorta
Coronary Vessels
Blood Vessels
1991
30 Citations (Scopus)

Anomalous origin of the right pulmonary artery from the ascending aorta

Nakamura, Y., Yasui, H., Kado, H., Yonenaga, K., Shiokawa, Y. & Tokunaga, S., Jan 1 1991, In : The Annals of Thoracic Surgery. 52, 6, p. 1285-1291 7 p.

Research output: Contribution to journalArticle

Pulmonary Artery
Aorta
Brachiocephalic Trunk
Transplants
Pathologic Constriction
23 Citations (Scopus)

A rat model of esophageal varices

Tanoue, K., Kitano, S., Hashizume, M., Wada, H. & Sugimachi, K., Feb 1991, In : Hepatology. 13, 2, p. 353-358 6 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Ligation
Portal Hypertension
Portal Vein
Esophagus
38 Citations (Scopus)

Atrial and brain natriuretic peptide in adrenal steroidogenesis

Nawata, H., Ohashi, M., Haji, M., Takayanagi, R., Higuchi, K., Fujio, N., Hashiguchi, T., Ogo, A., Nakao, R., Ohnaka, K. & Nishi, Y., 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 40, 1-3, p. 367-379 13 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Atrial Natriuretic Factor Receptors
Aldosterone
Plasmas
9 Citations (Scopus)

Comparative effects of 5% ethanolamine oleate versus 5% sodium morrhuate for sclerotherapy of oesphageal varices

KITANO, S., WADA, H., YAMAGA, H., HASHIZUME, M., KOYANAGI, N., IWANAGA, T., ISO, Y. & SUGIMACHI, K., Oct 1991, In : Journal of Gastroenterology and Hepatology. 6, 5, p. 476-480 5 p.

Research output: Contribution to journalArticle

Sodium Morrhuate
Sclerotherapy
Varicose Veins
Esophageal and Gastric Varices
Hemorrhage
6 Citations (Scopus)

Conversion of big endothelin isopeptides to mature endothelin isopeptides by cultured bovine endothelial cells

Ohnaka, K., Takayanagi, R., Ohashi, M. & Nawata, H., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S17-S19

Research output: Contribution to journalArticle

Endothelins
Endothelin-1
Endothelial Cells
Metalloproteases
Cultured Cells