Department of Advanced Medical Initiatives

Research Output

Filter
Article
2019

Japanese periodical nationwide epidemiologic survey of aberrant portal hemodynamics

Ohfuji, S., Furuichi, Y., Akahoshi, T., Kage, M., Obara, K., Hashizume, M., Matsuura, T., Fukushima, W. & Nakamura, Y., Aug 1 2019, In : Hepatology Research. 49, 8, p. 890-901 12 p.

Research output: Contribution to journalArticle

Open Access

Jarvik 2000 axial flow ventricular assist device in right single ventricle after Fontan operation

Tanoue, Y., Fujino, T., Tatewaki, H. & Shiose, A., Dec 1 2019, In : Journal of Artificial Organs. 22, 4, p. 338-340 3 p.

Research output: Contribution to journalArticle

JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure ― digest version ―

behalf of the Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group, Jan 1 2019, In : Circulation Journal. 83, 10, p. 2084-2184 101 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

on behalf of the Japanese Circulation Society Joint Working Group, Jan 1 2019, In : Circulation Journal. 83, 5, p. 1085-1196 112 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Liprin-α4 as a new therapeutic target for SCLC as an upstream mediator of HIF1α

Onishi, H., Yamasaki, A., Nakamura, K., Ichimiya, S., Yanai, K., Umebayashi, M., Nagai, S. & Morisaki, T., Mar 1 2019, In : Anticancer research. 39, 3, p. 1179-1184 6 p.

Research output: Contribution to journalArticle

Mechano-chronotropic Unloading During the Acute Phase of Myocardial Infarction Markedly Reduces Infarct Size via the Suppression of Myocardial Oxygen Consumption

Sunagawa, G., Saku, K., Arimura, T., Nishikawa, T., Mannoji, H., Kamada, K., Abe, K., Kishi, T., Tsutsui, H. & Sunagawa, K., Apr 15 2019, In : Journal of Cardiovascular Translational Research. 12, 2, p. 124-134 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Nationwide survey of multidisciplinary care and cardiac rehabilitation for patients with heart failure in Japan ― An analysis of the AMED-CHF study ―

Kamiya, K., Yamamoto, T., Tsuchihashi-Makaya, M., Ikegame, T., Takahashi, T., Sato, Y., Kotooka, N., Saito, Y., Tsutsui, H., Miyata, H. & Isobe, M., Jan 1 2019, In : Circulation Journal. 83, 7, p. 1546-1552 7 p.

Research output: Contribution to journalArticle

Open Access

Non-Pulmonary Vein Triggers of Atrial Fibrillation Are Likely to Arise from Low-Voltage Areas in the Left Atrium

Kawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A. & Tsutsui, H., Dec 1 2019, In : Scientific reports. 9, 1, 12271.

Research output: Contribution to journalArticle

Open Access
Open Access

Number of Cardiologists per Cardiovascular Beds and In-Hospital Mortality for Acute Heart Failure: A Nationwide Study in Japan

Kanaoka, K., Okayama, S., Nakai, M., Sumita, Y., Onoue, K., Soeda, T., Nishimura, K., Kawakami, R., Okura, H., Miyamoto, Y., Yasuda, S., Tsutsui, H., Komuro, I., Ogawa, H. & Saito, Y., Sep 17 2019, In : Journal of the American Heart Association. 8, 18, p. e012282

Research output: Contribution to journalArticle

Open Access

Outcome of patients with functional single ventricular heart after pacemaker implantation: What makes it poor, and what can we do?

Kodama, Y., Kuraoka, A., Ishikawa, Y., Nakamura, M., Ushinohama, H., Sagawa, K., Umemoto, S., Hashimoto, T., Sakamoto, I., Ohtani, K., Ide, T., Tsutsui, H. & Ishikawa, S., Dec 2019, In : Heart Rhythm. 16, 12, p. 1870-1874 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma

Nakamura, S., Sadakari, Y., Ohtsuka, T., Okayama, T., Nakashima, Y., Gotoh, Y., Saeki, K., Mori, Y., Nakata, K., Miyasaka, Y., Onishi, H., Oda, Y., Goggins, M. & Nakamura, M., Jul 15 2019, In : Annals of Surgical Oncology. 26, 7, p. 2104-2111 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Patched 1-interacting Peptide Represses Fibrosis in Pancreatic Cancer to Augment the Effectiveness of Immunotherapy

Oyama, Y., Onishi, H., Koga, S., Murahashi, M., Ichimiya, S., Nakayama, K., Fujimura, A., Kawamoto, M., Imaizumi, A., Umebayashi, M., Ohuchida, K., Morisaki, T. & Nakamura, M., Jan 1 2019, (Accepted/In press) In : Journal of Immunotherapy.

Research output: Contribution to journalArticle

Pectoral Muscle Atrophy After Axillary Artery Cannulation for Aortic Arch Surgery

Imasaka, K. I., Tomita, Y., Nishijima, T., Tayama, E., Morita, S., Toriya, R. & Shiose, A., Sep 1 2019, In : Seminars in Thoracic and Cardiovascular Surgery. 31, 3, p. 414-421 8 p.

Research output: Contribution to journalArticle

Peripartum management of pregnant women with congenital heart disease

Yamasaki, K., Sawatari, H., Konagai, N., Kamiya, C. A., Yoshimatsu, J., Muneuchi, J., Watanabe, M., Fukuda, T., Mizuno, A., Sakamoto, I., Yamamura, K., Ohkusa, T., Tsutsui, H., Niwa, K. & Chishaki, A., Jan 1 2019, In : Circulation Journal. 83, 11, p. 2257-2264 8 p.

Research output: Contribution to journalArticle

Open Access

Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models

Tokutome, M., Matoba, T., Nakano, Y., Okahara, A., Fujiwara, M., Koga, J. I., Nakano, K., Tsutsui, H. & Egashira, K., Feb 1 2019, In : Cardiovascular research. 115, 2, p. 419-431 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Possible associations between palliative care conferences and positive outcomes when performing palliative care for patients with end-stage heart failure: a nationwide cross-sectional questionnaire survey

Kurozumi, Y., Oishi, S., Sugano, Y., Sakashita, A., Kotooka, N., Suzuki, M., Higo, T., Yumino, D., Takada, Y., Maeda, S., Yamabe, S., Washida, K., Takahashi, T., Ohtani, T., Sakata, Y. & Sato, Y., Mar 15 2019, In : Heart and Vessels. 34, 3, p. 452-461 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Predictive value of the induction test with atrial burst pacing with regard to long-term recurrence after ablation in persistent atrial fibrillation

Kawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A. & Tsutsui, H., Apr 1 2019, In : journal of arrhythmia. 35, 2, p. 223-229 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Prescription rates of guideline-directed medications are associated with in-hospital mortality among Japanese patients with acute myocardial infarction: A report from JROAD-DPC study

Nakao, K., Yasuda, S., Nishimura, K., Noguchi, T., Nakai, M., Miyamoto, Y., Sumita, Y., Shishido, T., Anzai, T., Ito, H., Tsutsui, H., Saito, Y., Komuro, I. & Ogawa, H., Jan 1 2019, In : Journal of the American Heart Association. 8, 7, e009692.

Research output: Contribution to journalArticle

Open Access

Primary percutaneous coronary intervention in elderly patients with acute myocardial infarction — An analysis from a Japanese nationwide claim-based database

Uemura, S., Okamoto, H., Nakai, M., Nishimura, K., Miyamoto, Y., Yasuda, S., Tanaka, N., Kohsaka, S., Kadota, K., Saito, Y., Tsutsui, H., Komuro, I., Ikari, Y., Ogawa, H. & Nakamura, M., Jan 1 2019, In : Circulation Journal. 83, 6, p. 1229-1238 10 p.

Research output: Contribution to journalArticle

Open Access

Primary pericardial mesothelioma presenting as constrictive pericarditis

Yamamoto, T., Ohtani, K., Tanoue, Y., Shiose, A. & Tsutsui, H., May 1 2019, In : European heart journal cardiovascular Imaging. 20, 5, 1 p.

Research output: Contribution to journalArticle

Prior exposure to placental ischemia causes increased salt sensitivity of blood pressure via vasopressin production and secretion in postpartum rats

Matsuura, T., Shinohara, K., Iyonaga, T., Hirooka, Y. & Tsutsui, H., Aug 1 2019, In : Journal of hypertension. 37, 8, p. 1657-1667 11 p.

Research output: Contribution to journalArticle

Proteinase-activated receptor 1 antagonism ameliorates experimental pulmonary hypertension

Kuwabara, Y., Tanaka-Ishikawa, M., Abe, K., Hirano, M., Hirooka, Y., Tsutsui, H., Sunagawa, K. & Hirano, K., Jul 1 2019, In : Cardiovascular research. 115, 8, p. 1357-1368 12 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor

Fujimura, A., Nakayama, K., Imaizumi, A., Kawamoto, M., Oyama, Y., Ichimiya, S., Umebayashi, M., Koya, N., Morisaki, T., Nakagawa, T. & Onishi, H., Oct 1 2019, In : Cancer Immunology, Immunotherapy. 68, 10, p. 1649-1660 12 p.

Research output: Contribution to journalArticle

Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study

Japanese Circulation Society with Resuscitation Science Study Group, Dec 21 2019, In : The Lancet. 394, 10216, p. 2255-2262 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2 Citations (Scopus)
1 Citation (Scopus)

Standard cardiac rehabilitation program for heart failure

Izawa, H., Yoshida, T., Ikegame, T., Izawa, K. P., Ito, Y., Okamura, H., Osada, N., Kinugawa, S., Kubozono, T., Kono, Y., Kobayashi, K., Nishigaki, K., Higo, T., Hirashiki, A., Miyazawa, Y., Morio, Y., Yanase, M., Yamada, S., Ikeda, H., Momomura, S. I. & 4 others, Kihara, Y., Yamamoto, K., Goto, Y. & Makita, S., Jan 1 2019, In : Circulation Journal. 83, 12, p. 2394-2398 5 p.

Research output: Contribution to journalArticle

Open Access

Suppressed baroreflex peripheral arc overwhelms augmented neural arc and incapacitates baroreflex function in rats with pulmonary arterial hypertension

Shinoda, M., Saku, K., Oga, Y., Tohyama, T., Nishikawa, T., Abe, K., Yoshida, K., Kuwabara, Y., Fujii, K., Ishikawa, T., Kishi, T., Sunagawa, K. & Tsutsui, H., Aug 1 2019, In : Experimental Physiology. 104, 8, p. 1164-1178 15 p.

Research output: Contribution to journalArticle

The evolution of surgical treatment for gastrointestinal cancers

Maehara, Y., Soejima, Y., Yoshizumi, T., Kawahara, N., Oki, E., Saeki, H., Akahoshi, T., Ikegami, T., Yamashita, Y. I., Furuyama, T., Sugimachi, K., Harada, N., Tagawa, T., Harimoto, N., Itoh, S., Sonoda, H., Ando, K., Nakashima, Y., Nagao, Y., Yamashita, N. & 17 others, Kasagi, Y., Yukaya, T., Kurihara, T., Tsutsumi, R., Takamori, S., Sasaki, S., Ikeda, T., Yonemitsu, Y., Fukuhara, T., Kitao, H., Iimori, M., Kataoka, Y., Wakasa, T., Suzuki, M., Teraishi, K., Yoshida, Y. & Mori, M., Nov 1 2019, In : International Journal of Clinical Oncology. 24, 11, p. 1333-1349 17 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Thoracic endografting increases cardiac afterload and leads to left ventricular hypertrophy in dogs

Yamashita, Y., Oishi, Y., Motomatsu, Y., Hirayama, K., Harada, T., Ushijima, T., Fujita, S., Kimura, S., Sonoda, H., Tatewaki, H., Tanoue, Y., Sunagawa, G., Nishikawa, T., Saku, K. & Shiose, A., Apr 1 2019, In : European Journal of Cardio-thoracic Surgery. 55, 4, p. 618-625 8 p.

Research output: Contribution to journalArticle

Tolerability, efficacy, and safety of bisoprolol vs. Carvedilol in japanese patients with heart failure and reduced ejection fraction: The CIBIS-J trial

CIBIS-J Investigators, Jan 1 2019, In : Circulation Journal. 83, 6, p. 1269-1277 9 p.

Research output: Contribution to journalArticle

Open Access

Unexpected, but reasonable association between anderson-fabry disease and coronary vasospasm

Matoba, T., Nakano, Y. & Tsutsui, H., Feb 2019, In : Circulation Journal. 83, 2, p. 283-284 2 p.

Research output: Contribution to journalArticle

2018

A new robotic-assisted flexible endoscope with single-hand control: endoscopic submucosal dissection in the ex vivo porcine stomach

Iwasa, T., Nakadate, R., Onogi, S., Okamoto, Y., Arata, J., Oguri, S., Ogino, H., Ihara, E., Ohuchida, K., Akahoshi, T., Ikeda, T., Ogawa, Y. & Hashizume, M., Jul 1 2018, In : Surgical endoscopy. 32, 7, p. 3386-3392 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Angiotensin receptor neprilysin inhibitor in Japanese patients with heart failure and reduced ejection fraction: Baseline characteristics and treatment of PARALLEL-HF trial

Tsutsui, H., Momomura, S. I., Saito, Y., Ito, H., Yamamoto, K., Ohishi, T., Okino, N., Kitamura, T. & Guo, W., Jan 1 2018, In : Circulation Journal. 82, 10, p. 2575-2583 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A novel histological examination with dynamic three-dimensional reconstruction from multiple immunohistochemically stained sections of a PD-L1-positive colon cancer

Korehisa, S., Ikeda, T., Okano, S., Saeki, H., Oki, E., Oda, Y., Hashizume, M. & Maehara, Y., Mar 2018, In : Histopathology. 72, 4, p. 697-703 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial

The NPB-06 study group, Feb 1 2018, In : Hepatology Research. 48, 3, p. E107-E116

Research output: Contribution to journalArticle

11 Citations (Scopus)

Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload

Yamashita, Y., Tatewaki, H., Matsumoto, T. & Shiose, A., Oct 1 2018, In : Interactive cardiovascular and thoracic surgery. 27, 4, p. 626-628 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Citations (Scopus)

Catumaxomab with activated T-cells efficiently lyses chemoresistant EpCAM-positive triple-negative breast cancer cell lines

Kubo, M., Umebayashi, M., Kurata, K., Mori, H., Kai, M., Onishi, H., Katano, M., Nakamura, M. & Morisaki, T., Jul 2018, In : Anticancer research. 38, 7, p. 4273-4279 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Clinical outcome and prognostic factors of malignant spinal dumbbell tumors

Matsumoto, Y., Kawaguchi, K., Fukushi, J. I., Endo, M., Setsu, N., Iida, K., Baba, S., Saiwai, H., Matsushita, A., Hayashida, M., Okada, S. & Nakashima, Y., Jan 1 2018, In : Spine Surgery and Related Research. 2, 4, p. 317-323 7 p.

Research output: Contribution to journalArticle

Open Access

Clinical results, adverse events, and change in end-organ function in elderly patients with heartmateii left ventricular assist device: Japanese multicenter study

behalf of the Japanese HeartMateII Investigators, Jan 1 2018, In : Circulation Journal. 82, 2, p. 409-418 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Combined gemcitabine and metronidazole is a promising therapeutic strategy for cancer stem-like cholangiocarcinoma

Kawamoto, M., Umebayashi, M., Tanaka, H., Koya, N., Nakagawa, S., Kawabe, K., Onishi, H., Nakamura, M. & Morisaki, T., May 2018, In : Anticancer research. 38, 5, p. 2739-2748 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Constrictive Pericarditis and Worsening Mitral Annular Disjunction After Long-Term Chylopericardium

Uchikawa, T., Ohtani, K., Muramatsu, K., Sonoda, H., Shiose, A. & Tsutsui, H., Aug 1 2018, In : Circulation. Heart failure. 11, 8, p. e004698

Research output: Contribution to journalArticle

1 Citation (Scopus)

Customization of laparoscopic gastric devascularization and splenectomy for gastric varices based on CT vascular anatomy

Kawanaka, H., Akahoshi, T., Nagao, Y., Kinjo, N., Yoshida, D., Matsumoto, Y., Harimoto, N., Itoh, S., Yoshizumi, T. & Maehara, Y., Jan 1 2018, In : Surgical endoscopy. 32, 1, p. 114-126 13 p.

Research output: Contribution to journalArticle

Design of a nationwide survey on palliative care for end-stage heart failure in Japan

Kurozumi, Y., Oishi, S., Sugano, Y., Sakashita, A., Kotooka, N., Suzuki, M., Higo, T., Yumino, D., Takada, Y., Maeda, S., Yamabe, S., Washida, K., Takahashi, T., Ohtani, T., Sakata, Y. & Sato, Y., Feb 2018, In : Journal of Cardiology. 71, 2, p. 202-211 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Diagnostic value of quantitative coronary flow reserve and myocardial blood flow estimated by dynamic 320 MDCT scanning in patients with obstructive coronary artery disease

Obara, M., Naya, M., Oyama-Manabe, N., Aikawa, T., Tomiyama, Y., Sasaki, T., Kikuchi, Y., Manabe, O., Katoh, C., Tamaki, N. & Tsutsui, H., Jul 1 2018, In : Medicine (United States). 97, 27, e11354.

Research output: Contribution to journalArticle

2 Citations (Scopus)