Department of Advanced Medical Initiatives

Research Output 1980 2020

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1993
1 Citation (Scopus)

Hereditary spherocytosis with congestive heart failure: Report of a case

Morita, M., Hashizume, M., Kanematsu, T., Sugimachi, K. & Makizumi, K., May 1 1993, In : Surgery today. 23, 5, p. 458-461 4 p.

Research output: Contribution to journalArticle

Hereditary Spherocytosis
Heart Failure
Cardiovascular Agents
Splenectomy
Jaundice
67 Citations (Scopus)

Laparoscopic ligation of splenic artery aneurysm

Hashizume, M., Ohta, M., Ueno, K., Okadome, K. & Sugimachi, K., Mar 1993, In : Surgery. 113, 3, p. 352-354 3 p.

Research output: Contribution to journalArticle

Splenic Artery
Aneurysm
Ligation
Spleen
Cholelithiasis
5 Citations (Scopus)

Laparoscopic oversewing of a bleeding Mallory-Weiss tear under endoscopic guidance

Kitano, S., Ueno, K., Hashizume, M., Ohta, M., Tomikawa, M. & Sugimachi, K., Sep 1 1993, In : Surgical endoscopy. 7, 5, p. 445-446 2 p.

Research output: Contribution to journalArticle

Mallory-Weiss Syndrome
Hemorrhage
Esophagogastric Junction
Lacerations
Tears
119 Citations (Scopus)

Purification and characterization of a phosphoramidon-sensitive endothelin-converting enzyme in porcine aortic endothelium

Ohnaka, K., Takayanagi, R., Nishikawa, M., Haji, M. & Nawata, H., Jan 1 1993, In : Journal of Biological Chemistry. 268, 35, p. 26759-26766 8 p.

Research output: Contribution to journalArticle

Endothelins
Endothelin-1
Endothelium
Purification
Swine
Myocardial Contraction
Diastole
Systole
Cardiomegaly
Cytoskeleton
24 Citations (Scopus)

Revised technique of cardiopulmonary bypass in one-stage repair of interrupted aortic arch complex

Yasui, H., Kado, H., Yonenaga, K., Kawasaki, S., Shiokawa, Y., Kouno, H., Tominaga, R., Kawachi, Y. & Tokunaga, K., May 1993, In : The Annals of Thoracic Surgery. 55, 5, p. 1166-1171 6 p.

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Thoracic Aorta
Catheterization
Aorta
Truncus Arteriosus
10 Citations (Scopus)

Successful treatment of early hepatocellular carcinoma and concomitant esophageal varices

Higashi, H., Matsumata, T., Utsunomiya, T., Koyanagi, N., Hashizume, M. & Sugimachi, K., May 1 1993, In : World journal of surgery. 17, 3, p. 398-402 5 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Hepatocellular Carcinoma
Liver
Sclerotherapy
Survival Rate
2 Citations (Scopus)

The role of endothelin in adrenal medulla: identification of endothelin and its receptor in two cases of pheochromocytoma

Ohnaka, K., Oike, M., Takayangi, R., Yanase, T., Haji, M. & Nawata, H., Mar 1993, In : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 3, p. 97-99 3 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Adrenal Medulla
Endothelins
Pheochromocytoma
Binding Sites
19 Citations (Scopus)

The significance of methicillin-resistant Staphylococcus Aureus infection in general surgery: A multivariate analysis of risk factors and preventive approaches

Shimada, M., Kamakura, T., Itasaka, H., Matsumata, T., Hashizume, M. & Sugimachi, K., Oct 1 1993, In : Surgery today. 23, 10, p. 880-884 5 p.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Multivariate Analysis
Infection
Aminoglycosides
Anti-Bacterial Agents
82 Citations (Scopus)

Vascular anatomy of duodenal varices: Angiographic and histopathological assessments

Hashizume, M., Tanoue, K., Ohta, M., Ueno, K., Sugimachi, K., Kashiwagi, M. & Sueishi, K., Jan 1 1993, In : American Journal of Gastroenterology. 88, 11, p. 1942-1945 4 p.

Research output: Contribution to journalArticle

Varicose Veins
Blood Vessels
Anatomy
Veins
Portography
1992
12 Citations (Scopus)

Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope

Tsutsui, M., Matsuguchi, T., Tsutsui, H., Yoshihara, S., Yamamoto, K., Shimokawa, H., Okamatsu, S., Hisanou, R. & Yoshida, T., Jan 1 1992, In : japanese heart journal. 33, 6, p. 875-879 5 p.

Research output: Contribution to journalArticle

Syncope
Bradycardia
Hypotension
Alcohols
Eating
8 Citations (Scopus)

Comparative effects of 5% ethanolamine oleate versus 5% ethanolamine oleate plus 1% polidocanol for sclerosing esophageal varices

Kitano, S., Wada, H., Tanoue, K., Hashizume, M., Koyanagi, N. & Sugimachi, K., Dec 1 1992, In : Hepato-gastroenterology. 39, 6, p. 546-548 3 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Sclerotherapy
Sclerosing Solutions
Injections
Esophageal Perforation
76 Citations (Scopus)

Effects of endoscopic injection sclerotherapy on portal hypertensive gastropathy: a prospective study

Tanoue, K., Hashizume, M., Wada, H., Ohta, M., Kitano, S. & Sugimachi, K., Jan 1 1992, In : Gastrointestinal endoscopy. 38, 5, p. 582-585 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Prospective Studies
Esophageal and Gastric Varices
Injections
Endoscopy
92 Citations (Scopus)

Endoscopic injection sclerotherapy for 1,000 patients with esophageal varices: A nine‐year prospective study

Hashizume, M., Kitano, S., Koyanagi, N., Tanoue, K., Ohta, M., Wada, H., Yamaga, H., Higashi, H., Iso, Y., Iwanaga, T. & Sugimachi, K., Jan 1992, In : Hepatology. 15, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Prospective Studies
Injections
Hepatocellular Carcinoma
111 Citations (Scopus)

Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor

Takayanagi, R., Ohnaka, K., Sakai, Y., Nakao, R., Yanase, T., Haji, M., Inagami, T., Furuta, H., Gou, D. F., Nakamuta, M. & Nawata, H., Mar 16 1992, In : Biochemical and Biophysical Research Communications. 183, 2, p. 910-916 7 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Angiotensin Receptors
Cloning
Molecular Cloning
Liver
2 Citations (Scopus)

Over-tube is preferable to free-hand technique to avoid recurrence of varices after endoscopic injection sclerotherapy prospective randomized trial

Kitano, S., Yahaga, H., Wada, H., Hashizume, M. & Sugimachi, K., Jan 1 1992, In : International Surgery. 77, 3, p. 137-140 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Partial purification of phosphoramidon-sensitive endothelin converting enzyme in porcine aortic endothelial cells: High affinity for Ricinus communis agglutinin

Ohnaka, K., Nishikawa, M., Takayanagi, R., Haji, M. & Nawata, H., Jun 15 1992, In : Biochemical and Biophysical Research Communications. 185, 2, p. 611-616 6 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Purification
Swine
Endothelial Cells
28 Citations (Scopus)

Sclerotherapy vs. esophageal transection vs. distal splenorenal shunt for the clinical management of esophageal varices in patients with child class A and B liver function: A prospective randomized trial

Kitano, S., Iso, Y., Hashizume, M., Yamaga, H., Koyanagi, N., Wada, H., Iwanaga, T., Ohta, M. & Sugimachi, K., Jan 1992, In : Hepatology. 15, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Surgical Splenorenal Shunt
Sclerotherapy
Esophageal and Gastric Varices
Liver
Injections
19 Citations (Scopus)

Splenic hyperkinetic state and splenic artery aneurysm in portal hypertension

Ohta, M., Hashizume, M., Tanoue, K., Kitano, S., Sugimachi, K. & Yasumori, K., Dec 1 1992, In : Hepato-gastroenterology. 39, 6, p. 529-532 4 p.

Research output: Contribution to journalArticle

Splenic Artery
Portal Hypertension
Aneurysm
Abdomen
Case-Control Studies

Surgical versus non-surgical treatment in patients with esophageal varices--a prospective randomized study

Kitano, S., Ohta, M., Ueno, K., Hashizume, M., Iso, Y., Koyanagi, N. & Sugimachi, K., Sep 1992, In : Nippon Geka Gakkai zasshi. 93, 9, p. 1156-1158 3 p.

Research output: Contribution to journalArticle

Surgical Splenorenal Shunt
Esophageal and Gastric Varices
Prospective Studies
Therapeutics
Hemorrhage

The Effect of Recombinant Human Erythropoietin on Pre and Postoperative Anemia in Patients Undergoing General Surgery —Multicentral Trial—

Yoshida, K., Muto, T., Mori, S., Nishihira, T., Okui, K., Tashiro, T., Morioka, Y., Muto, T., Suzuki, K., Abe, O., Ueda, M., Tsurumaru, M., Udagawa, H., Mori, T., Kanbayashi, J., Sugimachi, K., Hashizume, M., Shimazu, H. & Takao, S., Jan 1 1992, In : the japanese journal of gastroenterological surgery. 25, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

Erythropoietin
Anemia
Hematocrit
Blood Transfusion
Hemoglobins

The nature of inner cellular lining of the expanded polytetrafluoroethylene vascular graft: Immunohistochemical study

Kuwano, H., Hashizume, M., Yang, Y., Mohsen Kholoussy, A. & Matsumoto, T., Jan 1 1992, In : International Surgery. 77, 3, p. 186-189 4 p.

Research output: Contribution to journalArticle

Blood Vessel Prosthesis
Vascular Endothelium
Polytetrafluoroethylene
von Willebrand Factor
Blood Vessels
236 Citations (Scopus)
Osteotomy
Thigh
Hip
Necrosis
Steroids
1991
30 Citations (Scopus)

Anomalous origin of the right pulmonary artery from the ascending aorta

Nakamura, Y., Yasui, H., Kado, H., Yonenaga, K., Shiokawa, Y. & Tokunaga, S., Jan 1 1991, In : The Annals of Thoracic Surgery. 52, 6, p. 1285-1291 7 p.

Research output: Contribution to journalArticle

Pulmonary Artery
Aorta
Brachiocephalic Trunk
Transplants
Pathologic Constriction
23 Citations (Scopus)

A rat model of esophageal varices

Tanoue, K., Kitano, S., Hashizume, M., Wada, H. & Sugimachi, K., Feb 1991, In : Hepatology. 13, 2, p. 353-358 6 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Ligation
Portal Hypertension
Portal Vein
Esophagus
38 Citations (Scopus)

Atrial and brain natriuretic peptide in adrenal steroidogenesis

Nawata, H., Ohashi, M., Haji, M., Takayanagi, R., Higuchi, K., Fujio, N., Hashiguchi, T., Ogo, A., Nakao, R., Ohnaka, K. & Nishi, Y., 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 40, 1-3, p. 367-379 13 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Atrial Natriuretic Factor Receptors
Aldosterone
Plasmas
9 Citations (Scopus)

Comparative effects of 5% ethanolamine oleate versus 5% sodium morrhuate for sclerotherapy of oesphageal varices

KITANO, S., WADA, H., YAMAGA, H., HASHIZUME, M., KOYANAGI, N., IWANAGA, T., ISO, Y. & SUGIMACHI, K., Oct 1991, In : Journal of Gastroenterology and Hepatology. 6, 5, p. 476-480 5 p.

Research output: Contribution to journalArticle

Sodium Morrhuate
Sclerotherapy
Varicose Veins
Esophageal and Gastric Varices
Hemorrhage
6 Citations (Scopus)

Conversion of big endothelin isopeptides to mature endothelin isopeptides by cultured bovine endothelial cells

Ohnaka, K., Takayanagi, R., Ohashi, M. & Nawata, H., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S17-S19

Research output: Contribution to journalArticle

Endothelins
Endothelin-1
Endothelial Cells
Metalloproteases
Cultured Cells
12 Citations (Scopus)

Cultured bovine endothelial cells convert big endothelin isopeptides to mature endothelin isopeptides

Ohnaka, K., Takayanagi, R., Yamauchi, T., Umeda, F. & Nawata, H., Jun 7 1991, In : Biochemistry international. 23, 3, p. 499-506 8 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Endothelin-1
Endothelial Cells
Endothelin-3
2 Citations (Scopus)

Gastric bleeding after endoscopic injection sclerotherapy for esophageal varices may be fatal

Higashi, H., Kitano, S., Hashizume, M., Yamaga, H., Wada, H. & Sugimachi, K., Jan 1 1991, In : International Surgery. 76, 4, p. 214-217 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Giant bar-type esophageal varices not eradicated by repeated injection sclerotherapy

Hashizume, M., Tanoue, K., Kitano, S., Ohta, M. & Sugimachi, K., Jan 1 1991, In : Gastrointestinal endoscopy. 37, 2, p. 187-189 3 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

High Rate of Portal Thrombosis After Splenectomy in Patients with Esophageal Varices and Idiopathic Portal Hypertension

Eguchi, A., Hashizume, M., Kitano, S., Tanoue, K., Wada, H. & Sugimachi, K., Jun 1991, In : Archives of Surgery. 126, 6, p. 752-755 4 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Splenectomy
Thrombosis
Liver Cirrhosis
Banti's syndrome
13 Citations (Scopus)

Multiple subtypes of endothelin receptors in human and porcine tissues: Characterization by ligand binding, affinity labeling, and regional distribution

Takayanagi, R., Ohnaka, K., Takasaki, C., Ohashi, M. & Nawata, H., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S127-S130

Research output: Contribution to journalArticle

Endothelin Receptors
Endothelin-1
Swine
Endothelin-3
Ligands
49 Citations (Scopus)

Multiple subtypes of endothelin receptors in porcine tissues: characterization by ligand binding, affinity labeling and regional distribution

Takayanagi, R., Ohnaka, K., Takasaki, C., Ohashi, M. & Nawata, H., Jan 1 1991, In : Regulatory Peptides. 32, 1, p. 23-37 15 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Endothelin-1
Labeling
Swine
Endothelin-3
1 Citation (Scopus)

Platelet aggregability and prostacyclin/thromboxane a2 ratio after endoscopic injection sclerotherapy with different sclerosants

Yamaga, H., Hashizume, M., Wada, H., Kitano, S. & Sugimachi, K., Jan 1 1991, In : European Surgical Research. 23, 3-4, p. 228-234 7 p.

Research output: Contribution to journalArticle

Sodium Morrhuate
Sclerosing Solutions
Thromboxane A2
Sclerotherapy
Epoprostenol

Recommendation for open heart surgery in infancy

Yasui, H., Kado, H., Yonenaga, K., Nakamura, Y., Shiokawa, Y., Tominaga, R., Matsuzaki, H., Kawachi, Y. & Tokunaga, K., Jan 1 1991, In : Kyobu geka. The Japanese journal of thoracic surgery. 44, 13, p. 1072-1079 8 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Induced Heart Arrest
Cardiopulmonary Bypass
Heart Diseases
Patient Care
14 Citations (Scopus)

Structure-activity relationships of sarafotoxins: chemical syntheses of chimera peptides of sarafotoxins S6b and S6c

Takasaki, C., Aimoto, S., Kitazumi, K., Tasaka, K., Shiba, T., Nishiki, K., Furukawa, Y., Takayanagi, R., Ohnaka, K. & Nawata, H., Jun 6 1991, In : European Journal of Pharmacology. 198, 2-3, p. 165-169 5 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Peptides
sarafotoxins s6
Vasoconstrictor Agents
3 Citations (Scopus)

Successful treatment of Budd-Chiari syndrome with early gastric cancer

Kakeji, Y., Hashizume, M., Kitano, S., Hasuo, K. & Sugimachi, K., Jan 1 1991, In : International Surgery. 76, 1, p. 55-57 3 p.

Research output: Contribution to journalArticle

1990

A case of acyclovir-resistant herpes simplex encephalitis improved dramatically by vidarabine (Ara-A)

Ohnaka, K., Kurata, T., Miyake, T., Sasagasako, N. & Ishimoto, S., Jan 1 1990, In : Japanese Journal of National Medical Services. 44, 7, p. 728-732 5 p.

Research output: Contribution to journalArticle

Vidarabine
Herpes Simplex Encephalitis
Acyclovir
Cerebrospinal Fluid
Muscle Rigidity
1 Citation (Scopus)

A case of hypopituitarism associated with empty sella and agenesis of corpus callosum, a variant form of septo-optic-pituitary dysplasia

Fukutomi, T., Masakado, M., Takayanagi, R., Ohnaka, K., Sekiya, K., Haji, M., Ohasi, M. & Nawata, H., Dec 1990, In : Fukuoka igaku zasshi = Hukuoka acta medica. 81, 12, p. 396-401 6 p.

Research output: Contribution to journalArticle

Septo-Optic Dysplasia
Agenesis of Corpus Callosum
Hypopituitarism
Pituitary Function Tests
Septum Pellucidum
53 Citations (Scopus)

Alterations of elastic architecture in human aortic dissecting aneurysm

Nakashima, Y., Shiokawa, Y. & Sueishi, K., Jan 1 1990, In : Laboratory Investigation. 62, 6, p. 751-760 10 p.

Research output: Contribution to journalArticle

Dissecting Aneurysm
Aortic Aneurysm
Elastin
formic acid
Necrosis
130 Citations (Scopus)

Endoscopic classification of gastric varices

Hashizume, M., Kitano, S., Yamaga, H., Koyanagi, N. & Sugimachi, K., Jan 1 1990, In : Gastrointestinal endoscopy. 36, 3, p. 276-280 5 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Color
Cardia
Varicose Veins
Endoscopy

Endoscopic markers of impending varceal hemorrhage: Correlation with the pressure in the varices

Beppu, K. & Hashizume, M., Jan 1990, In : Hepatology. 11, 1, p. 147-148 2 p.

Research output: Contribution to journalArticle

Varicose Veins
Hemorrhage
Pressure
Ascites
Color
167 Citations (Scopus)

Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells

Yamauchi, T., Ohnaka, K., Takayanagi, R., Umeda, F. & Nawata, H., Jul 2 1990, In : FEBS Letters. 267, 1, p. 16-18 3 p.

Research output: Contribution to journalArticle

Endothelial cells
Endothelin-1
Endothelial Cells
Glucose
Aldehyde Reductase
6 Citations (Scopus)

Eradication of oesophageal varices recurring after portal non‐decompressive surgery by injection sclerotherapy

Hashizume, M., Kitano, S., Yamaga, H., Wada, H. & Sugimachi, K., Aug 1990, In : British Journal of Surgery. 77, 8, p. 940-943 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Injections
Hemorrhage
Esophageal Stenosis
18 Citations (Scopus)

Hemodynamic and morphological changes in the dog kidney after injection of 5% ethanolamine oleate into the superior vena cava

Wada, H., Hashizume, M., Yamaga, H., Kitano, S. & Sugimachi, K., Jan 1 1990, In : European Surgical Research. 22, 2, p. 63-70 8 p.

Research output: Contribution to journalArticle

Superior Vena Cava
Renal Circulation
Hemodynamics
Dogs
Kidney
4 Citations (Scopus)

Heterogeneous distribution of a diffusional tracer in the aortic wall of normal and atherosclerotic rabbits

Tsutsui, H., Tomoike, H. & Nakamura, M., Jan 1 1990, In : Circulation research. 67, 2, p. 368-375 8 p.

Research output: Contribution to journalArticle

Thoracic Aorta
Tunica Intima
Radioactivity
Antipyrine
Abdominal Aorta
6 Citations (Scopus)

Hypercoagulopathy after repeated injection of 5% ethanolamine oleate to sclerose esophageal varices

Hashizume, M., Yamaga, H., Kitano, S. & Sugimachi, K., Dec 1 1990, In : Hepato-gastroenterology. 37, 6, p. 565-568 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Sclerosis
Injections
Latex
103 Citations (Scopus)

Identification and characterization of endothelin converting activity in cultured bovine endothelial cells

Ohnaka, K., Takayanagi, R., Yamauchi, T., Okazaki, H., Ohashi, M., Umeda, F. & Nawata, H., May 16 1990, In : Biochemical and Biophysical Research Communications. 168, 3, p. 1128-1136 9 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Endothelin-1
Endothelial Cells
Egtazic Acid

Mucosal denudation of the lower esophagus for prevention of recurrence of varices

Kitano, S., Wada, H., Tanoue, K., Hashizume, M. & Sugimachi, K., Apr 1 1990, In : Nippon rinsho. Japanese journal of clinical medicine. 48, 4, p. 770-773 4 p.

Research output: Contribution to journalArticle