Department of Advanced Medical Initiatives

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Estrogen receptor-β gene polymorphism and colorectal cancer risk: Effect modified by body mass index and isoflavone intake

Honma, N., Yamamoto, K., Ohnaka, K., Morita, M., Toyomura, K., Kono, S., Muramatsu, M., Arai, T., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., Feb 15 2012, In : International Journal of Cancer. 132, 4, p. 951-958 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Evaluating the Efficacy, Safety, and Tolerability of Serelaxin When Added to Standard Therapy in Asian Patients With Acute Heart Failure: Design and Rationale of RELAX-AHF-ASIA Trial

Sato, N., Lam, C. S. P., Teerlink, J. R., Greenberg, B. H., Tsutsui, H., Oh, B. H., Zhang, J., Lefkowitz, M., Hua, T. A., Holbro, T., Marshood, M., Wang, X. L. & Ge, J., Jan 1 2017, In : Journal of Cardiac Failure. 23, 1, p. 63-71 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients

Onishi, H., Morisaki, T., Kuroki, H., Matsumoto, K., Baba, E., Kuga, H., Tanaka, M. & Katano, M., Sep 1 2005, In : Anticancer research. 25, 5, p. 3445-3451 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Evaluation of a transection method for distal pancreatectomy: A comparative study on the use of electrosurgical and stapling devices in swine.

Ikeda, T., Akahoshi, T., Kawanaka, H., Uchiyama, H., Yamashita, Y. I., Morita, M., Oki, E., Saeki, H., Sugimachi, K., Ikegami, T., Yoshizumi, T., Soejima, Y., Shirabe, K., Mimori, K., Watanabe, M., Hashizume, M. & Maehara, Y., Jan 1 2013, In : Fukuoka igaku zasshi = Hukuoka acta medica. 104, 12, p. 515-522 8 p.

Research output: Contribution to journalArticle

Evaluation of chronic ischemic heart disease with myocardial perfusion and regional contraction analysis by contrast-enhanced 256-MSCT

Higuchi, K., Nagao, M., Matsuo, Y., Kamitani, T., Yonezawa, M., Jinnouchi, M., Yamasaki, Y., Abe, K., Baba, S., Mukai, Y., Higo, T., Sunagawa, K. & Honda, H., Feb 1 2013, In : Japanese Journal of Radiology. 31, 2, p. 123-132 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
3 Citations (Scopus)

Evaluation of techniques to prevent colorectal anastomotic leakage

Ikeda, T., Kumashiro, R., Oki, E., Taketani, K., Ando, K., Aishima, S., Akahoshi, T., Morita, M. & Maehara, Y., Apr 1 2015, In : Journal of Surgical Research. 194, 2, p. 450-457 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Evaluation of the 10-year history of a 2-day standardized laparoscopic surgical skills training program at Kyushu University

Tomikawa, M., Uemura, M., Kenmotsu, H., Konishi, K., Ohuchida, K., Okazaki, K., Ieiri, S., Tanoue, K. & Hashizume, M., Jun 1 2016, In : Surgery today. 46, 6, p. 750-756 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Evaluation of the effect of sodium–glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR-Reduced trial

on behalf of the EMPEROR-Reduced Trial Committees and Investigators, Executive Committee, National Coordinators, Consulting Statistician, Clinical Events Committee, Scientific Excellence Committee & Data Monitoring Committee, Oct 1 2019, In : European Journal of Heart Failure. 21, 10, p. 1270-1278 9 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
5 Citations (Scopus)

Excellent Midterm Outcome of Extracardiac Conduit Total Cavopulmonary Connection: Results of 126 Cases

Nakano, T., Kado, H., Tachibana, T., Hinokiyama, K., Shiose, A., Kajimoto, M. & Ando, Y., Nov 1 2007, In : Annals of Thoracic Surgery. 84, 5, p. 1619-1626 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Excess L-arginine restores endothelium-dependent relaxation impaired by monocrotaline pyrrole

Cheng, W., Oike, M., Hirakawa, M., Ohnaka, K., Koyama, T. & Ito, Y., Sep 15 2005, In : Toxicology and Applied Pharmacology. 207, 3, p. 187-194 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Exclusion of nonisolated splenic vein in distal splenorenal shunt for prevention of portal malcirculation

Inokuchi, K., Beppu, K., Koyanagi, N., Nagamine, K., Hashizume, M. & Sugimachi, K., Jan 1 1984, In : Annals of surgery. 200, 6, p. 711-717 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Exosomes secreted from monocyte-derived dendritic cells support in vitro naive CD4+ T cell survival through NF-κB activation

Matsumoto, K., Morisaki, T., Kuroki, H., Kubo, M., Onishi, H., Nakamura, K., Nakahara, C., Kuga, H., Baba, E., Nakamura, M., Hirata, K., Tanaka, M. & Katano, M., Sep 1 2004, In : Cellular Immunology. 231, 1-2, p. 20-29 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Experience with the Norwood procedure without circulatory arrest

Imoto, Y., Kado, H., Shiokawa, Y., Minami, K. & Yasui, H., Nov 1 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 5, p. 879-882 4 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Experimental mouse model of lumbar ligamentum flavum hypertrophy

Saito, T., Yokota, K., Kobayakawa, K., Hara, M., Kubota, K., Harimaya, K., Kawaguchi, K., Hayashida, M., Matsumoto, Y., Doi, T., Shiba, K., Nakashima, Y. & Okada, S., Jan 2017, In : PloS one. 12, 1, e0169717.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Expression, subcellular localization, and cloning of the 130-kDa regulatory subunit of myosin phosphatase in porcine aortic endothelial cells

Hirano, M., Niiro, N., Hirano, K., Nishimura, J., Hartshorne, D. J. & Kanaide, H., Jan 19 1999, In : Biochemical and Biophysical Research Communications. 254, 2, p. 490-496 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Expression and characterization of myristoylated preS1-conjugated nanocages for targeted cell delivery

Murata, M., Piao, J. S., Narahara, S., Kawano, T., Hamano, N., Kang, J. H., Asai, D., Ugawa, R. & Hashizume, M., Jun 2015, In : Protein Expression and Purification. 110, p. 52-56 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Nishida, T., Shimokawa, H., Oi, K., Tatewaki, H., Uwatoku, T., Abe, K., Matsumoto, Y., Kajihara, N., Eto, M., Matsuda, T., Yasui, H., Takeshita, A. & Sunagawa, K., Nov 9 2004, In : Circulation. 110, 19, p. 3055-3061 7 p.

Research output: Contribution to journalArticle

264 Citations (Scopus)

Extradural nodular fasciitis arising in the spinal canal

Kubota, K., Okada, S., Maeda, T., Matsumoto, Y., Sakamoto, A., Harimaya, K., Saiwai, H., Kumamaru, H., Oda, Y. & Iwamoto, Y., Jan 15 2012, In : Spine. 37, 2, p. E133-E137

Research output: Contribution to journalArticle

2 Citations (Scopus)

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells

Okumura, T., Ohuchida, K., Sada, M., Abe, T., Endo, S., Koikawa, K., Iwamoto, C., Miura, D., Mizuuchi, Y., Moriyama, T., Nakata, K., Miyasaka, Y., Manabe, T., Ohtsuka, T., Nagai, E., Mizumoto, K., Oda, Y., Hashizume, M. & Nakamura, M., Jan 1 2017, In : Oncotarget. 8, 11, p. 18280-18295 16 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Extreme hyperbilirubinemia induced by endoscopic injection sclerotherapy in a patient with esophageal varices and thalassemia: Report of a case

Nishioka, K., Hashizume, M., Kitano, S., Ohta, M., Ueno, K., Tomikawa, M., Higashi, H., Okamura, T. & Sugimachi, K., Mar 4 1996, In : Surgery today. 26, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ezetimibe in combination with statins ameliorates endothelial dysfunction in coronary arteries after stenting: the CuVIC trial (effect of cholesterol absorption inhibitor usage on target vessel dysfunction after coronary stenting), a multicenter randomized controlled trial

Takase, S., Matoba, T., Nakashiro, S., Mukai, Y., Inoue, S., Oi, K., Higo, T., Katsuki, S., Takemoto, M., Suematsu, N., Eshima, K., Miyata, K., Yamamoto, M., Usui, M., Sadamatsu, K., Satoh, S., Kadokami, T., Hironaga, K., Ichi, I., Todaka, K. & 3 others, Kishimoto, J., Egashira, K. & Sunagawa, K., Feb 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 2, p. 350-358 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Facilitation of proteasomal degradation of p27Kip1 by N-terminal cleavage and their sequence requirements

Hirano, K., Ihara, E., Hirano, M., Nishimura, J., Nawata, H. & Kanaide, H., Sep 10 2004, In : FEBS Letters. 574, 1-3, p. 111-115 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Factors associated with the clinical outcomes of paediatric out-of-hospital cardiac arrest in Japan

Nagata, T., Abe, T., Noda, E., Hasegawa, M., Hashizume, M. & Hagihara, A., Mar 4 2014, In : BMJ open. 4, 2, e003481.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Factors associated with the outcome of out-of-hospital cardiopulmonary arrest among people over 80 years old in Japan

Nagata, T., Abe, T., Hasegawa, M. & Hagihara, A., Apr 1 2017, In : Resuscitation. 113, p. 63-69 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fast alignment of 3D geometrical models and 2D grayscale images using 2D distance maps

Iwashita, Y., Kurazume, R., Konishi, K., Nakamoto, M., Hashizume, M. & Hasegawa, T., Dec 1 2007, In : Systems and Computers in Japan. 38, 14, p. 52-62 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Fast model-image registration using a two-dimensional distance map for surgical navigation system

Iwashita, Y., Kurazume, R., Konishi, K., Nakamoto, M., Aburaya, N., Sato, Y., Hashizume, M. & Hasegawa, T., Jun 1 2007, In : Advanced Robotics. 21, 7, p. 751-770 20 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Fatal cardiac hemochromatosis in a patient with hereditary spherocytosis

Fujino, T., Inoue, S., Katsuki, S., Higo, T., Ide, T., Oda, Y. & Tsutsui, H., Jan 1 2018, In : International heart journal. 59, 2, p. 427-430 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Feasibility of an AI-Based Measure of the Hand Motions of Expert and Novice Surgeons

Uemura, M., Tomikawa, M., Miao, T., Souzaki, R., Ieiri, S., Akahoshi, T., Lefor, A. K. & Hashizume, M., Jan 1 2018, In : Computational and Mathematical Methods in Medicine. 2018, 9873273.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Feasibility of laparoscopic cholecystectomy for patients with a nonvisualized gallbladder on drip infusion cholangiography

Tomikawa, M., Kitano, S., Iso, Y., Hashizume, M., Moriyama, M., Ohta, M., Higashi, H. & Sugimachi, K., Apr 1995, In : Surgical Laparoscopy and Endoscopy. 5, 2, p. 121-124 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
3 Citations (Scopus)

Fifteen years' experience with left gastric venous caval shunt for esophageal varices

Inokuchi, K., Beppu, K., Koyanagi, N., Nagamine, K., Hashizume, M., Iwanaga, T. & Sugimachi, K., Oct 1 1984, In : World journal of surgery. 8, 5, p. 716-721 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

First Successful Pre-Distribution of Stable Iodine Tablets under Japan's New Policy after the Fukushima Daiichi Nuclear Accident

Ojino, M., Yoshida, S., Nagata, T., Ishii, M. & Akashi, M., Jun 1 2017, In : Disaster Medicine and Public Health Preparedness. 11, 3, p. 365-369 5 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction

Hayashidani, S., Tsutsui, H., Shiomi, T., Suematsu, N., Kinugawa, S., Ide, T., Wen, J. & Takeshita, A., Feb 19 2002, In : Circulation. 105, 7, p. 868-873 6 p.

Research output: Contribution to journalArticle

290 Citations (Scopus)

Folate-related nutrients, genetic polymorphisms, and colorectal cancer risk: The Fukuoka colorectal cancer study

Morita, M., Yin, G., Yoshimitsu, S. I., Ohnaka, K., Toyomura, K., Kono, S., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., 2013, In : Asian Pacific Journal of Cancer Prevention. 14, 11, p. 6249-6256 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Folding procedure to diminish type 3 endoleakage after open stent graft surgery with TEVAR extension

Onzuka, T., Furukawa, K., Tayama, E., Morita, S. & Shiose, A., Nov 1 2019, In : General thoracic and cardiovascular surgery. 67, 11, p. 999-1000 2 p.

Research output: Contribution to journalArticle

Formulation of wire control mechanism for surgical robot to create virtual reality environment aimed at conducting surgery inside the body

Suzuki, N., Hattori, A., Ieiri, S., Tomikawa, M., Kenmotsu, H. & Hashizume, M., Jan 1 2013, In : Studies in Health Technology and Informatics. 184, p. 424-430 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Förster Resonance Energy Transfer-Based Self-Assembled Nanoprobe for Rapid and Sensitive Detection of Postoperative Pancreatic Fistula

Hamano, N., Murata, M., Kawano, T., Piao, J. S., Narahara, S., Nakata, R., Akahoshi, T., Ikeda, T. & Hashizume, M., Mar 2 2016, In : ACS Applied Materials and Interfaces. 8, 8, p. 5114-5123 10 p.

Research output: Contribution to journalArticle

Functional loss of DHRS7C induces intracellular ca2+ overload and myotube enlargement in C2C12 cells via calpain activation

Arai, S., Ikeda, M., Ide, T., Matsuo, Y., Fujino, T., Hirano, K., Sunagawa, K. & Tsutsui, H., Jan 1 2017, In : American Journal of Physiology - Cell Physiology. 312, 1, p. C29-C39

Research output: Contribution to journalArticle

3 Citations (Scopus)

Future perspective of gastrointestinal 'intelligent' endoscopy

Konishi, K. & Hashizume, M., Jul 2010, In : Nippon rinsho. Japanese journal of clinical medicine. 68, 7, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

Future prospect of gallbladder therapy using Hedgehog signaling inhibitor

Onishi, H., Jan 1 2017, In : Chinese Clinical Oncology. 6, 1, 11.

Research output: Contribution to journalArticle

Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes

Tasaka, T., Akiyoshi, T., Yamaguchi, K., Tanaka, M., Onishi, H. & Katano, M., Dec 1 2010, In : Anticancer research. 30, 12, p. 4999-5010 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Gastric bleeding after endoscopic injection sclerotherapy for esophageal varices may be fatal

Higashi, H., Kitano, S., Hashizume, M., Yamaga, H., Wada, H. & Sugimachi, K., Jan 1 1991, In : International Surgery. 76, 4, p. 214-217 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Gastric endoscopic submucosal dissection using novel 26-mm articulating devices: an ex vivo comparative and in vivo feasibility study

Nakadate, R., Nakamura, S., Moriyama, T., Kenmotsu, H., Oguri, S., Arata, J., Uemura, M., Ohuchida, K., Akahoshi, T., Ikeda, T. & Hashizume, M., Sep 1 2015, In : Endoscopy. 47, 9, p. 820-824 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Gastroenterological Surgery: Pancreas

Tanaka, M., Tomikawa, M., Nakamura, M., Nakamura, Y., Misawa, T., Akahoshi, T., Kinjyo, N., Sumiyoshi, H., Tsutsumi, K., Tsutsumi, N., Nakashima, H., Higashida, M., Fujiwara, Y., Matsushita, A. & Matsumoto, M., Aug 1 2015, In : Asian journal of endoscopic surgery. 8, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells

Onimaru, M., Ohuchida, K., Egami, T., Mizumoto, K., Nagai, E., Cui, L., Toma, H., Matsumoto, K., Hashizume, M. & Tanaka, M., Aug 1 2010, In : Cancer Gene Therapy. 17, 8, p. 541-549 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the japanese population

Nakamura, A., Niimura, H., Kuwabara, K., Takezaki, T., Morita, E., Wakai, K., Hamajima, N., Nishida, Y., Turin, T. C., Suzuki, S., Ohnaka, K., Uemura, H., Ozaki, E., Hosono, S., Mikami, H., Kubo, M. & Tanaka, H., Dec 20 2013, In : PloS one. 8, 12, e82046.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Generation of a rat monoclonal antibody specific for Hsp72

Tanaka, M., Shiota, M., Okada, S., Harada, A., Odawara, J., Mun, S., Iwao, H. & Ohkawa, Y., Aug 1 2011, In : Hybridoma. 30, 4, p. 397-400 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)