Department of Advanced Medical Initiatives

Research Output 1980 2019

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1994
78 Citations (Scopus)

Laparoscopic splenectomy

Hashizume, M., Sugimachi, K., Kitano, S., Shimada, M., Baba, H., Ueno, K., Ohta, M. & Tomikawa, M., Jun 1994, In : The American Journal of Surgery. 167, 6, p. 611-614 4 p.

Research output: Contribution to journalArticle

Splenectomy
Splenic Vein
Splenic Artery
Pneumoperitoneum
Nylons
10 Citations (Scopus)

Laparoscopy–assisted colostomy

Hashizume, M., Haraguchi, Y., Ikeda, Y., Kajiyama, K., Fujie, T. & Sugimachi, K., Feb 1994, In : Surgical Laparoscopy and Endoscopy. 4, 1, p. 70-72 3 p.

Research output: Contribution to journalArticle

Colostomy
Laparoscopic Cholecystectomy
Sigmoid Colon
Ascites
Ovarian Neoplasms
16 Citations (Scopus)

Laparoscopy-Assisted devascularization of the lower esophagus and upper stomach in the management of gastric varices

Kitano, S., Tomikawa, M., Iso, Y., Hashizume, M., Monyama, M. & Sugimachi, K., Jan 1 1994, In : Endoscopy. 26, 5, p. 470-473 4 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Laparoscopy
Esophagus
Stomach
Enbucrilate
40 Citations (Scopus)

Laparoscopy-assisted surgery: A new technique for transhiatal esophageal dissection

Sadanaga, N., Kuwano, H., Watanabe, M., Ikebe, M., Mori, M., Maekawa, S., Hashizume, M., Kitano, S. & Sugimachi, K., 1994, In : The American Journal of Surgery. 168, 4, p. 355-357 3 p.

Research output: Contribution to journalArticle

Laparoscopy
Dissection
Esophagectomy
Intraoperative Complications
Carcinoma
1 Citation (Scopus)

Metoclopramide inhibits development of esophageal varices in rat model

Ohta, M., Hashizume, M., Tanoue, K., Ueno, K., Komori, K., Ishii, T., Kitano, S. & Sugimachi, K., Sep 1 1994, In : Digestive Diseases and Sciences. 39, 9, p. 1853-1858 6 p.

Research output: Contribution to journalArticle

Metoclopramide
Esophageal and Gastric Varices
Lower Esophageal Sphincter
Control Groups
Esophagus
31 Citations (Scopus)

Molecular Cloning and Characterization of the Promoter for Human Type-I Angiotensin II Receptor Gene

Takayanagi, R., Ohnaka, K., Sakai, Y., Ikuyama, S. & Nawata, H., May 15 1994, In : Biochemical and Biophysical Research Communications. 200, 3, p. 1264-1270 7 p.

Research output: Contribution to journalArticle

Angiotensin Receptors
5' Flanking Region
Cloning
Molecular Cloning
Chloramphenicol O-Acetyltransferase
50 Citations (Scopus)

Native β-adrenergic support for left ventricular dysfunction in experimental mitral regurgitation normalizes indexes of pump and contractile function

Nagatsu, M., Zile, M. R., Tsutsui, H., Schmid, P. G., DeFreyte, G., Cooper IV, G. & Carabello, B. A., Feb 1994, In : Circulation. 89, 2, p. 818-826 9 p.

Research output: Contribution to journalArticle

Mitral Valve Insufficiency
Left Ventricular Dysfunction
Adrenergic Agents
Nervous System
Stress Fibers
5 Citations (Scopus)

Reoperation for transposition of the great arteries: mid-term results and reoperation after arterial switch operation

Kado, H., Asoh, T., Imoto, Y., Shiokawa, Y., Yamasaki, M. & Yasui, H., Jan 1 1994, In : Rinshō kyōbu geka = Japanese annals of thoracic surgery. 14, 3, p. 192-197 6 p.

Research output: Contribution to journalArticle

Transposition of Great Vessels
Reoperation
Pulmonary Valve Stenosis
Supravalvular Aortic Stenosis
Aortic Valve Insufficiency
20 Citations (Scopus)

The effects of complete versus incomplete mitral valve repair in experimental mitral regurgitation

Nagatsu, M., Ishihara, K., Zile, M. R., Tsutsui, H., Tagawa, H., DeFreyte, G., Tanaka, R., Cooper, G. & Carabello, B. A., Jan 1 1994, In : Journal of Thoracic and Cardiovascular Surgery. 107, 2, p. 416-423 8 p.

Research output: Contribution to journalArticle

Mitral Valve Insufficiency
Mitral Valve
Dogs
Pulmonary Wedge Pressure
Cardiac Output
1993

A Comparative Study of Ceftizoxime and Cefazolin Prophylaxis in Upper Digestive Tract and Biliary Surgery: A Prospective Randomised Clinical Trial

The Cooperative Study Group, Jan 1993, In : Drug Investigation. 5, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Ceftizoxime
Cefazolin
Gastrointestinal Tract
Randomized Controlled Trials
Infection
16 Citations (Scopus)

Albumin inhibits hemolysis of erythrocytes induced by ethanolamine oleate during endoscopic injection sclerotherapy

Ohta, M., Hashizume, M., Ueno, K., Tanoue, K. & Sugimachi, K., Jan 1 1993, In : Hepato-gastroenterology. 40, 1, p. 65-68 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Hemolysis
Albumins
Erythrocytes
Injections
11 Citations (Scopus)

A transparent endoscopic elastic band ligating device

Hashizume, M., Ohta, M., Ueno, K., Tomikawa, M., Kitano, S. & Sugimachi, K., Jan 1 1993, In : Gastrointestinal endoscopy. 39, 5, p. 686-688 3 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium

Tsutsui, H., Ishihara, K. & Cooper IV, G., Jan 1 1993, In : Science. 260, 5108, p. 682-687 6 p.

Research output: Contribution to journalArticle

Cardiomegaly
Microtubules
Myocardium
Cytoskeleton
Cardiac Myocytes
94 Citations (Scopus)

Endoscopic ligation of esophageal varices compared with injection sclerotherapy: a prospective randomized trial

Hashizume, M., Ohta, M., Ueno, K., Tanoue, K., Kitano, S. & Sugimachi, K., Jan 1 1993, In : Gastrointestinal endoscopy. 39, 2, p. 123-126 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Ligation
Injections
Sclerosing Solutions
1 Citation (Scopus)

Hereditary spherocytosis with congestive heart failure: Report of a case

Morita, M., Hashizume, M., Kanematsu, T., Sugimachi, K. & Makizumi, K., May 1 1993, In : Surgery today. 23, 5, p. 458-461 4 p.

Research output: Contribution to journalArticle

Hereditary Spherocytosis
Heart Failure
Cardiovascular Agents
Splenectomy
Jaundice
67 Citations (Scopus)

Laparoscopic ligation of splenic artery aneurysm

Hashizume, M., Ohta, M., Ueno, K., Okadome, K. & Sugimachi, K., Mar 1993, In : Surgery. 113, 3, p. 352-354 3 p.

Research output: Contribution to journalArticle

Splenic Artery
Aneurysm
Ligation
Spleen
Cholelithiasis
5 Citations (Scopus)

Laparoscopic oversewing of a bleeding Mallory-Weiss tear under endoscopic guidance

Kitano, S., Ueno, K., Hashizume, M., Ohta, M., Tomikawa, M. & Sugimachi, K., Sep 1 1993, In : Surgical endoscopy. 7, 5, p. 445-446 2 p.

Research output: Contribution to journalArticle

Mallory-Weiss Syndrome
Hemorrhage
Esophagogastric Junction
Lacerations
Tears
119 Citations (Scopus)

Purification and characterization of a phosphoramidon-sensitive endothelin-converting enzyme in porcine aortic endothelium

Ohnaka, K., Takayanagi, R., Nishikawa, M., Haji, M. & Nawata, H., Jan 1 1993, In : Journal of Biological Chemistry. 268, 35, p. 26759-26766 8 p.

Research output: Contribution to journalArticle

Endothelins
Endothelin-1
Endothelium
Purification
Swine
Myocardial Contraction
Diastole
Systole
Cardiomegaly
Cytoskeleton
24 Citations (Scopus)

Revised technique of cardiopulmonary bypass in one-stage repair of interrupted aortic arch complex

Yasui, H., Kado, H., Yonenaga, K., Kawasaki, S., Shiokawa, Y., Kouno, H., Tominaga, R., Kawachi, Y. & Tokunaga, K., Jan 1 1993, In : The Annals of Thoracic Surgery. 55, 5, p. 1166-1171 6 p.

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Thoracic Aorta
Catheterization
Aorta
Truncus Arteriosus
10 Citations (Scopus)

Successful treatment of early hepatocellular carcinoma and concomitant esophageal varices

Higashi, H., Matsumata, T., Utsunomiya, T., Koyanagi, N., Hashizume, M. & Sugimachi, K., May 1 1993, In : World journal of surgery. 17, 3, p. 398-402 5 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Hepatocellular Carcinoma
Liver
Sclerotherapy
Survival Rate
2 Citations (Scopus)

The role of endothelin in adrenal medulla: identification of endothelin and its receptor in two cases of pheochromocytoma

Ohnaka, K., Oike, M., Takayangi, R., Yanase, T., Haji, M. & Nawata, H., Mar 1993, In : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 3, p. 97-99 3 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Adrenal Medulla
Endothelins
Pheochromocytoma
Binding Sites
19 Citations (Scopus)

The significance of methicillin-resistant Staphylococcus Aureus infection in general surgery: A multivariate analysis of risk factors and preventive approaches

Shimada, M., Kamakura, T., Itasaka, H., Matsumata, T., Hashizume, M. & Sugimachi, K., Oct 1 1993, In : Surgery today. 23, 10, p. 880-884 5 p.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Multivariate Analysis
Infection
Aminoglycosides
Anti-Bacterial Agents
82 Citations (Scopus)

Vascular anatomy of duodenal varices: Angiographic and histopathological assessments

Hashizume, M., Tanoue, K., Ohta, M., Ueno, K., Sugimachi, K., Kashiwagi, M. & Sueishi, K., Jan 1 1993, In : American Journal of Gastroenterology. 88, 11, p. 1942-1945 4 p.

Research output: Contribution to journalArticle

Varicose Veins
Blood Vessels
Anatomy
Veins
Portography
1992
8 Citations (Scopus)

Comparative effects of 5% ethanolamine oleate versus 5% ethanolamine oleate plus 1% polidocanol for sclerosing esophageal varices

Kitano, S., Wada, H., Tanoue, K., Hashizume, M., Koyanagi, N. & Sugimachi, K., Dec 1 1992, In : Hepato-gastroenterology. 39, 6, p. 546-548 3 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Sclerotherapy
Sclerosing Solutions
Injections
Esophageal Perforation
76 Citations (Scopus)

Effects of endoscopic injection sclerotherapy on portal hypertensive gastropathy: a prospective study

Tanoue, K., Hashizume, M., Wada, H., Ohta, M., Kitano, S. & Sugimachi, K., Jan 1 1992, In : Gastrointestinal endoscopy. 38, 5, p. 582-585 4 p.

Research output: Contribution to journalArticle

Sclerotherapy
Prospective Studies
Esophageal and Gastric Varices
Injections
Endoscopy
91 Citations (Scopus)

Endoscopic injection sclerotherapy for 1,000 patients with esophageal varices: A nine‐year prospective study

Hashizume, M., Kitano, S., Koyanagi, N., Tanoue, K., Ohta, M., Wada, H., Yamaga, H., Higashi, H., Iso, Y., Iwanaga, T. & Sugimachi, K., Jan 1992, In : Hepatology. 15, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Prospective Studies
Injections
Hepatocellular Carcinoma
111 Citations (Scopus)

Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor

Takayanagi, R., Ohnaka, K., Sakai, Y., Nakao, R., Yanase, T., Haji, M., Inagami, T., Furuta, H., Gou, D. F., Nakamuta, M. & Nawata, H., Mar 16 1992, In : Biochemical and Biophysical Research Communications. 183, 2, p. 910-916 7 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Angiotensin Receptors
Cloning
Molecular Cloning
Liver
2 Citations (Scopus)

Over-tube is preferable to free-hand technique to avoid recurrence of varices after endoscopic injection sclerotherapy prospective randomized trial

Kitano, S., Yahaga, H., Wada, H., Hashizume, M. & Sugimachi, K., Jan 1 1992, In : International Surgery. 77, 3, p. 137-140 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Partial purification of phosphoramidon-sensitive endothelin converting enzyme in porcine aortic endothelial cells: High affinity for Ricinus communis agglutinin

Ohnaka, K., Nishikawa, M., Takayanagi, R., Haji, M. & Nawata, H., Jun 15 1992, In : Biochemical and Biophysical Research Communications. 185, 2, p. 611-616 6 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Purification
Swine
Endothelial Cells
28 Citations (Scopus)

Sclerotherapy vs. esophageal transection vs. distal splenorenal shunt for the clinical management of esophageal varices in patients with child class A and B liver function: A prospective randomized trial

Kitano, S., Iso, Y., Hashizume, M., Yamaga, H., Koyanagi, N., Wada, H., Iwanaga, T., Ohta, M. & Sugimachi, K., Jan 1992, In : Hepatology. 15, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Surgical Splenorenal Shunt
Sclerotherapy
Esophageal and Gastric Varices
Liver
Injections
19 Citations (Scopus)

Splenic hyperkinetic state and splenic artery aneurysm in portal hypertension

Ohta, M., Hashizume, M., Tanoue, K., Kitano, S., Sugimachi, K. & Yasumori, K., Dec 1 1992, In : Hepato-gastroenterology. 39, 6, p. 529-532 4 p.

Research output: Contribution to journalArticle

Splenic Artery
Portal Hypertension
Aneurysm
Abdomen
Case-Control Studies

Surgical versus non-surgical treatment in patients with esophageal varices--a prospective randomized study

Kitano, S., Ohta, M., Ueno, K., Hashizume, M., Iso, Y., Koyanagi, N. & Sugimachi, K., Sep 1992, In : Nippon Geka Gakkai zasshi. 93, 9, p. 1156-1158 3 p.

Research output: Contribution to journalArticle

Surgical Splenorenal Shunt
Esophageal and Gastric Varices
Prospective Studies
Therapeutics
Hemorrhage

The Effect of Recombinant Human Erythropoietin on Pre and Postoperative Anemia in Patients Undergoing General Surgery —Multicentral Trial—

Yoshida, K., Muto, T., Mori, S., Nishihira, T., Okui, K., Tashiro, T., Morioka, Y., Muto, T., Suzuki, K., Abe, O., Ueda, M., Tsurumaru, M., Udagawa, H., Mori, T., Kanbayashi, J., Sugimachi, K., Hashizume, M., Shimazu, H. & Takao, S., Jan 1 1992, In : the japanese journal of gastroenterological surgery. 25, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

Erythropoietin
Anemia
Hematocrit
Blood Transfusion
Hemoglobins

The nature of inner cellular lining of the expanded polytetrafluoroethylene vascular graft: Immunohistochemical study

Kuwano, H., Hashizume, M., Yang, Y., Mohsen Kholoussy, A. & Matsumoto, T., Jan 1 1992, In : International Surgery. 77, 3, p. 186-189 4 p.

Research output: Contribution to journalArticle

Blood Vessel Prosthesis
Vascular Endothelium
Polytetrafluoroethylene
von Willebrand Factor
Blood Vessels
231 Citations (Scopus)
Osteotomy
Thigh
Hip
Necrosis
Steroids
1991
29 Citations (Scopus)

Anomalous origin of the right pulmonary artery from the ascending aorta

Nakamura, Y., Yasui, H., Kado, H., Yonenaga, K., Shiokawa, Y. & Tokunaga, S., Jan 1 1991, In : The Annals of Thoracic Surgery. 52, 6, p. 1285-1291 7 p.

Research output: Contribution to journalArticle

Pulmonary Artery
Aorta
Brachiocephalic Trunk
Transplants
Pathologic Constriction
23 Citations (Scopus)

A rat model of esophageal varices

Tanoue, K., Kitano, S., Hashizume, M., Wada, H. & Sugimachi, K., Feb 1991, In : Hepatology. 13, 2, p. 353-358 6 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Ligation
Portal Hypertension
Portal Vein
Esophagus
38 Citations (Scopus)

Atrial and brain natriuretic peptide in adrenal steroidogenesis

Nawata, H., Ohashi, M., Haji, M., Takayanagi, R., Higuchi, K., Fujio, N., Hashiguchi, T., Ogo, A., Nakao, R., Ohnaka, K. & Nishi, Y., 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 40, 1-3, p. 367-379 13 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Atrial Natriuretic Factor Receptors
Aldosterone
Plasmas
9 Citations (Scopus)

Comparative effects of 5% ethanolamine oleate versus 5% sodium morrhuate for sclerotherapy of oesphageal varices

KITANO, S., WADA, H., YAMAGA, H., HASHIZUME, M., KOYANAGI, N., IWANAGA, T., ISO, Y. & SUGIMACHI, K., Oct 1991, In : Journal of Gastroenterology and Hepatology. 6, 5, p. 476-480 5 p.

Research output: Contribution to journalArticle

Sodium Morrhuate
Sclerotherapy
Varicose Veins
Esophageal and Gastric Varices
Hemorrhage
6 Citations (Scopus)

Conversion of big endothelin isopeptides to mature endothelin isopeptides by cultured bovine endothelial cells

Ohnaka, K., Takayanagi, R., Ohashi, M. & Nawata, H., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S17-S19

Research output: Contribution to journalArticle

Endothelins
Endothelin-1
Endothelial Cells
Metalloproteases
Cultured Cells
12 Citations (Scopus)

Cultured bovine endothelial cells convert big endothelin isopeptides to mature endothelin isopeptides

Ohnaka, K., Takayanagi, R., Yamauchi, T., Umeda, F. & Nawata, H., Jun 7 1991, In : Biochemistry international. 23, 3, p. 499-506 8 p.

Research output: Contribution to journalArticle

Endothelins
Endothelial cells
Endothelin-1
Endothelial Cells
Endothelin-3
2 Citations (Scopus)

Gastric bleeding after endoscopic injection sclerotherapy for esophageal varices may be fatal

Higashi, H., Kitano, S., Hashizume, M., Yamaga, H., Wada, H. & Sugimachi, K., Jan 1 1991, In : International Surgery. 76, 4, p. 214-217 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Giant bar-type esophageal varices not eradicated by repeated injection sclerotherapy

Hashizume, M., Tanoue, K., Kitano, S., Ohta, M. & Sugimachi, K., Jan 1 1991, In : Gastrointestinal endoscopy. 37, 2, p. 187-189 3 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

High Rate of Portal Thrombosis After Splenectomy in Patients with Esophageal Varices and Idiopathic Portal Hypertension

Eguchi, A., Hashizume, M., Kitano, S., Tanoue, K., Wada, H. & Sugimachi, K., Jun 1991, In : Archives of Surgery. 126, 6, p. 752-755 4 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Splenectomy
Thrombosis
Liver Cirrhosis
Banti's syndrome
13 Citations (Scopus)

Multiple subtypes of endothelin receptors in human and porcine tissues: Characterization by ligand binding, affinity labeling, and regional distribution

Takayanagi, R., Ohnaka, K., Takasaki, C., Ohashi, M. & Nawata, H., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S127-S130

Research output: Contribution to journalArticle

Endothelin Receptors
Endothelin-1
Swine
Endothelin-3
Ligands
49 Citations (Scopus)

Multiple subtypes of endothelin receptors in porcine tissues: characterization by ligand binding, affinity labeling and regional distribution

Takayanagi, R., Ohnaka, K., Takasaki, C., Ohashi, M. & Nawata, H., Jan 1 1991, In : Regulatory Peptides. 32, 1, p. 23-37 15 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Endothelin-1
Labeling
Swine
Endothelin-3
1 Citation (Scopus)

Platelet aggregability and prostacyclin/thromboxane a2 ratio after endoscopic injection sclerotherapy with different sclerosants

Yamaga, H., Hashizume, M., Wada, H., Kitano, S. & Sugimachi, K., Jan 1 1991, In : European Surgical Research. 23, 3-4, p. 228-234 7 p.

Research output: Contribution to journalArticle

Sodium Morrhuate
Sclerosing Solutions
Thromboxane A2
Sclerotherapy
Epoprostenol
217 Citations (Scopus)

Presence of non-selective type of endothelin receptor on vascular endothelium and its linkage to vasodilation

Takayanagi, R., Kitazumi, K., Takasaki, C., Ohnaka, K., Aimoto, S., Tasaka, K., Ohashi, M. & Nawata, H., Apr 22 1991, In : FEBS Letters. 282, 1, p. 103-106 4 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Vascular Endothelium
Vasodilation
Endothelium
Rats

Recommendation for open heart surgery in infancy

Yasui, H., Kado, H., Yonenaga, K., Nakamura, Y., Shiokawa, Y., Tominaga, R., Matsuzaki, H., Kawachi, Y. & Tokunaga, K., Jan 1 1991, In : Kyobu geka. The Japanese journal of thoracic surgery. 44, 13, p. 1072-1079 8 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Induced Heart Arrest
Cardiopulmonary Bypass
Heart Diseases
Patient Care