Department of Advanced Medical Initiatives

Research Output 1980 2019

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2015
29 Citations (Scopus)

Three-dimensional liver model based on preoperative CT images as a tool to assist in surgical planning for hepatoblastoma in a child

Sozaki, R., Kinoshita, Y., Ieiri, S., Hayashida, M., Koga, Y., Shirabe, K., Hara, T., Maehara, Y., Hashizume, M. & Taguchi, T., Apr 23 2015, In : Pediatric surgery international. 31, 6, p. 593-596 4 p.

Research output: Contribution to journalArticle

Hepatoblastoma
Liver
Drug Therapy
Neoplasms
Three Dimensional Printing
134 Citations (Scopus)

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., NKelly, T., Saleheen, D., Lehne, B., Leach, I. M., Drong, A. W., Abbott, J., Wahl, S., Tan, S. T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. S., Bonder, M. J. & 225 others, Chen, P., Dehghan, A., Edwards, T. L., Esko, T., Go, M. J., Harris, S. E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C. C., Kleber, M. E., Li, H., Mok, Z. Y., Nakatochi, M., Sapari, N. S., Saxena, R., Stewart, A. F. R., Stolk, L., Tabara, Y., Teh, A. L., Wu, Y., Wu, J. Y., Zhang, Y., Aits, I., Da Silva Couto Alves, A., Das, S., Dorajoo, R., CHopewell, J., Kim, Y. K., WKoivula, R., Luan, JA., Lyytikäinen, L. P., NNguyen, Q., Pereira, M. A., Postmus, I., TRaitakari, O., Scannell Bryan, M., Scott, R. A., Sorice, R., Tragante, V., Traglia, M., White, J., Yamamoto, K., Zhang, Y., Adair, L. S., Ahmed, A., Akiyama, K., Asif, R., Aung, T., Barroso, I., Bjonnes, A., Braun, T. R., Cai, H., Chang, L. C., Chen, C. H., Cheng, C. Y., Chong, Y. S., Collins, R., Courtney, R., Davies, G., Delgado, G., Do, L. D., Doevendans, P. A., Gansevoort, R. T., Gao, Y. T., Grammer, T. B., Grarup, N., Grewal, J., Gu, D., SWander, G., Hartikainen, A. L., Hazen, S. L., He, J., Heng, C. K., Hixso, E. J. A., Hofman, A., Hsu, C., Huang, W., Husemoen, L. L. N., Hwang, J. Y., Ichihara, S., Igase, M., Isono, M., Justesen, J. M., Katsuya, T., GKibriya, M., Kim, Y. J., Kishimoto, M., Koh, W. P., Kohara, K., Kumari, M., Kwek, K., Lee, N. R., Lee, J., Liao, J., Lieb, W., Liewald, D. C. M., Matsubara, T., Matsushita, Y., Meitinger, T., Mihailov, E., Milani, L., Mills, R., Mononen, N., Müller-Nurasyid, M., Nabika, T., Nakashima, E., Ng, H. K., Nikus, K., Nutile, T., Ohkubo, T., Keizo, O., Parish, S., Paternoster, L., Peng, H., Peters, A., TPham, S., Pinidiyapathirage, M. J., Rahman, M., Rakugi, H., Rolandsson, O., Rozario, M. A., Ruggiero, D., Sala, C. F., Sarju, R., Shimokawa, K., Snieder, H., SparsØ, T., Spiering, W., Starr, J. M., Stott, D. J., OStram, D., Sugiyama, T., Szymczak, S., Tang, W. H. W., Tong, L., Trompet, S., Turjanmaa, V., Ueshima, H., Uitterlinden, A. G., Umemura, S., Vaarasmaki, M., Dam, R. M., Van Gilst, W. H., Van Veldhuisen, D. J., Viikari, J. S., Waldenberger, M., Wang, Y., Wang, A., Wilson, R., Wong, T. Y., Xiang, Y. B., Yamaguchi, S., Ye, X., Young, R. D., Young, T. L., Yuan, J. M., Zhou, X., Asselbergs, F. W., Ciullo, M., Clarke, R., Deloukas, P., Franke, A., Paul, W. F., Franks, S., Friedlander, Y., Gross, M. D., Guo, Z., Hansen, T., Jarvelin, M. R., JØrgensen, T., Jukema, J. W., Kähönen, M., Kajio, H., Kivimaki, M., Lee, J. Y., Lehtimäki, T., Linneberg, A., Miki, T., Pedersen, O., Samani, N. J., SØrensen, T. I. A., Takayanagi, R., Toniolo, D., Ahsan, H., Allayee, H., Chen, Y. T., Danesh, J., Deary, I. J., Franco, O. H., Franke, L., THeijman, B., Holbrook, J. D., Isaacs, A., Kim, B. J., Lin, X., Liu, J., März, W., Metspalu, A., Mohlke, K. L., Sangher, K., Harambir, D., Shu, X. O., Van Meurs, J. B. J., Vithana, E., Wickremasinghe, A. R., Wijmenga, C., Wolffenbuttel, B. H. W., Yokota, M., Zheng, W., Zhu, D., Vineis, P., Kyrtopoulos, S. A., Kleinjans, J. C. S., McCarthy, M. I., Soong, R., Gieger, C., Scott, J., Teo, Y. Y., He, J., Elliott, P., Tai, E. S., Van Der Harst, P., Kooner, J. S. & Chambers, J. C., Nov 1 2015, In : Nature genetics. 47, 11, p. 1282-1293 12 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
DNA Methylation
Blood Pressure
Single Nucleotide Polymorphism
1 Citation (Scopus)

Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction

Yasuda, M., Saeki, H., Nakashima, Y., Yukaya, T., Tsutsumi, S., Tajiri, H., Zaitsu, Y., Tsuda, Y., Kasagi, Y., Andou, K., Imamura, Y., Ohgaki, K., Akahoshi, T., Oki, E. & Maehara, Y., Sep 18 2015, In : Journal of Medical Investigation. 62, 3, p. 149-153 5 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Liver
Liver Diseases
Blood
Therapeutics
1 Citation (Scopus)

Trypsin-induced biphasic regulation of tone in the porcine lower esophageal sphincter

Tanaka, Y., Ihara, E., Hirano, K., Takahashi, S., Hirano, M., Nakamura, K., Akiho, H., Oda, Y. & Takayanagi, R., Apr 5 2015, In : European Journal of Pharmacology. 752, p. 97-105 9 p.

Research output: Contribution to journalArticle

Lower Esophageal Sphincter
Trypsin
Swine
rho-Associated Kinases
Protein Kinases
2014
18 Citations (Scopus)

Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans

Kobayakawa, K., Kumamaru, H., Saiwai, H., Kubota, K., Ohkawa, Y., Kishimoto, J., Yokota, K., Ideta, R., Shiba, K., Saitoh, H., Inoue, K., Iwamoto, Y. & Okada, S., Jan 1 2014, In : Science Translational Medicine. 6, 256, 256ra137.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Hyperglycemia
Obese Mice
Nervous System Trauma
Blood Glucose
29 Citations (Scopus)

Afferent vagal nerve stimulation resets baroreflex neural arc and inhibits sympathetic nerve activity

Saku, K., Kishi, T., Sakamoto, K., Hosokawa, K., sakamoto, T., Murayama, Y., Kakino, T., Ikeda, M., Ide, T. & Sunagawa, K., Jan 1 2014, In : Physiological Reports. 2, 9, e12136.

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Baroreflex
Arterial Pressure
Splanchnic Nerves
Carotid Sinus
30 Citations (Scopus)

Analysis of hand motion differentiates expert and novice surgeons

Uemura, M., Tomikawa, M., Kumashiro, R., Miao, T., Sozaki, R., Ieiri, S., Ouchida, K., Lefor, A. T. & Hashizume, M., May 1 2014, In : Journal of Surgical Research. 188, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

Hand
Orbit
Gravitation
Needles
Surgeons
4 Citations (Scopus)

An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro

Umebayashi, M., Kiyota, A., Koya, N., Tanaka, H., Ohnishi, H., Katano, M. & Morisaki, T., Aug 1 2014, In : Anticancer research. 34, 8, p. 4509-4520 12 p.

Research output: Contribution to journalArticle

Bispecific Antibodies
Neoplastic Stem Cells
T-Lymphocytes
Pancreatic Neoplasms
Neoplasms
7 Citations (Scopus)

A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: The J-MICC Study

Katsuura-Kamano, S., Uemura, H., Arisawa, K., Yamaguchi, M., Hamajima, N., Wakai, K., Okada, R., Suzuki, S., Taguchi, N., Kita, Y., Keizo, O., Kairupan, T. S., Matsui, D., Oze, I., Mikami, H., Kubo, M. & Tanaka, H., Jan 1 2014, In : Endocrine. 47, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Japan
Triglycerides
Cohort Studies
Body Mass Index
10 Citations (Scopus)

A preregistered STAMP method for image-guided temporal bone surgery

Oka, M., Cho, B., Matsumoto, N., Hong, J., Jinnouchi, M., Ouchida, R., Komune, S. & Hashizume, M., Jan 1 2014, In : International journal of computer assisted radiology and surgery. 9, 1, p. 119-126 8 p.

Research output: Contribution to journalArticle

Temporal Bone
Operating rooms
Surgery
Bone
Operating Rooms
1 Citation (Scopus)

A shallow chest correlates with the aortic position in the normal spine: Features resembling those observed in structural scoliosis

Doi, T., Matsumoto, Y., Tono, O., Tarukado, K., Harimaya, K., Okada, S., Kubota, K., Hayashida, M. & Iwamoto, Y., Aug 30 2014, In : Scoliosis. 9, 1, 14.

Research output: Contribution to journalArticle

Scoliosis
Spine
Thorax
Rib Cage
16 Citations (Scopus)

A single port laparoscopic surgery robot with high force transmission and a large workspace

Cheon, B., Gezgin, E., Ji, D. K., Tomikawa, M., Hashizume, M., Kim, H. J. & Hong, J., Jan 1 2014, In : Surgical endoscopy. 28, 9, p. 2719-2729 11 p.

Research output: Contribution to journalArticle

Laparoscopy
Robotics
Postoperative Period
Cicatrix
15 Citations (Scopus)

Assessment of quality of life during long-term treatment of tolvaptan in refractory heart failure: Design and rationale of the AQUA-TLV study

Imamura, T., Kinugawa, K., Ohtani, T., Sakata, Y., Higo, T., Kinugawa, S., Tsutsui, H., Sunagawa, K. & Komuro, I., Jan 1 2014, In : International heart journal. 55, 3, p. 264-267 4 p.

Research output: Contribution to journalArticle

Heart Failure
Quality of Life
Japan
Therapeutics
Furosemide
3 Citations (Scopus)

Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population

Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group, Jan 1 2014, In : Journal of epidemiology. 24, 5, p. 379-384 6 p.

Research output: Contribution to journalArticle

Fasting
Body Mass Index
Genotype
Glucose
Blood Glucose
4 Citations (Scopus)

A surgical navigation system for guiding exact cochleostomy using auditory feedback: A clinical feasibility study

Cho, B., Matsumoto, N., Komune, S. & Hashizume, M., Jan 1 2014, In : BioMed Research International. 2014, 769659.

Research output: Contribution to journalArticle

Feasibility Studies
Navigation systems
Navigation
Microscopes
Feedback
4 Citations (Scopus)

Balloon-occluded retrograde transvenous obliteration is feasible for prolonged portosystemic shunts after living donor liver transplantation

Nagao, Y., Akahoshi, T., uehara, H., Hashimoto, N., Kinjo, N., Kawanaka, H., Tomikawa, M., Uchiyama, H., Yoshizumi, T., Soejima, Y., Shirabe, K. & Maehara, Y., Jan 1 2014, In : Surgery Today. 44, 4, p. 633-639 7 p.

Research output: Contribution to journalArticle

Surgical Portasystemic Shunt
Living Donors
Liver Transplantation
Portal Vein
Liver Diseases
15 Citations (Scopus)

Combination of exercise training and diet restriction normalizes limited exercise capacity and impaired skeletal muscle function in diet-induced diabetic mice

Suga, T., Kinugawa, S., Takada, S., Kadoguchi, T., Fukushima, A., Homma, T., Masaki, Y., Furihata, T., Takahashi, M., Sobirin, M. A., Ono, T., Hirabayashi, K., Yokota, T., Tanaka, S., Okita, K. & Tsutsui, H., Jan 1 2014, In : Endocrinology. 155, 1, p. 68-80 13 p.

Research output: Contribution to journalArticle

Diabetic Diet
Skeletal Muscle
Exercise
Diet
High Fat Diet
6 Citations (Scopus)

Comparison of open, laparoscopic, and hand-assisted laparoscopic devascularization of the upper stomach and splenectomy for treatment of esophageal and gastric varices: a single-center experience

Akahoshi, T., uehara, H., Tomikawa, M., Kawanaka, H., Hashizume, M. & Maehara, Y., May 1 2014, In : Asian journal of endoscopic surgery. 7, 2, p. 138-144 7 p.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Splenectomy
Stomach
Hand
Portal Hypertension

Easy and rapid registration for image guided surgery using dentally affixed reference

Oka, M., Matsumoto, N., Cho, B., Ouchida, R., Jinouchi, M., Hasizume, M. & Komune, S., Jan 1 2014, In : Oto-Rhino-Laryngology Tokyo. 56, 5, p. 293-295 3 p.

Research output: Contribution to journalArticle

Computer-Assisted Surgery
Fiducial Markers
Operating Rooms
23 Citations (Scopus)

Effect of laparoscopic splenectomy on portal haemodynamics in patients with liver cirrhosis and portal hypertension

Kawanaka, H., Akahoshi, T., Kinjo, N., Iguchi, T., Ninomiya, M., Yamashita, Y. I., Ikegami, T., Yoshizumi, T., Shirabe, K. & Maehara, Y., Jan 1 2014, In : British Journal of Surgery. 101, 12, p. 1585-1593 9 p.

Research output: Contribution to journalArticle

Portal Hypertension
Splenectomy
Liver Cirrhosis
Hemodynamics
Endothelin-1
3 Citations (Scopus)

Efficacy and safety of splenectomy in telaprevir-based triple therapy for chronic hepatitis C patients with thrombocytopenia and advanced fibrosis

Ogawa, E., Furusyo, N., Nakamuta, M., Kajiwara, E., Nomura, H., Dohmen, K., Takahashi, K., Satoh, T., Azuma, K., Kawano, A., Tanabe, Y., Kotoh, K., Shimoda, S., Akahoshi, T., Maehara, Y. & Hayashi, J., Jan 1 2014, In : Journal of Gastroenterology and Hepatology (Australia). 29, 9, p. 1728-1735 8 p.

Research output: Contribution to journalArticle

Splenectomy
Chronic Hepatitis C
Thrombocytopenia
Fibrosis
Safety
27 Citations (Scopus)

Emergency endoscopy for acute gastrointestinal bleeding: Prognostic value of endoscopic hemostasis and the AIMS65 score in Japanese patients

Nakamura, S., Matsumoto, T., Sugimori, H., Esaki, M., Kitazono, T. & Hashizume, M., Jan 1 2014, In : Digestive Endoscopy. 26, 3, p. 369-376 8 p.

Research output: Contribution to journalArticle

Endoscopic Hemostasis
Gastrointestinal Endoscopy
Emergencies
Hemorrhage
Blood Transfusion
14 Citations (Scopus)

Factors associated with the clinical outcomes of paediatric out-of-hospital cardiac arrest in Japan

Nagata, T., Abe, T., Noda, E., Hasegawa, M., Hashizume, M. & Hagihara, A., Mar 4 2014, In : BMJ open. 4, 2, e003481.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Pediatric Hospitals
Japan
Validation Studies
Emergency Responders
500 Citations (Scopus)

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B. & 312 others, Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., OBoehm, B., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Chan, J. C. N., Chang, L. C., Chang, T. J., Chang, Y. C., Charpentier, G., Chen, C. H., Chen, H., Chen, Y. T., Chia, K. S., Chidambaram, M., Chines, P. S., Cho, N. H., Cho, Y. M., Chuang, L. M., Collins, F. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., Van Dam, R. M., Danesh, J., Das, D., De Faire, U., Dedoussis, G., Deloukas, P., Dimas, A. S., Dina, C., Doney, A. S. F., Donnelly, P. J., Dorkhan, M., Van Duijn, C., Dupuis, J., Edkins, S., Elliott, P., Emilsson, V., Erbel, R., Eriksson, J. G., Escobedo, J., Esko, T., Eury, E., Florez, J. C., Fontanillas, P., Forouhi, N. G., Forsen, T., Fox, C., Fraser, R. M., Frayling, T. M., Froguel, P., Frossard, P., Gao, Y., Gertow, K., Gieger, C., Gigante, B., Grallert, H., Grant, G. B., Groop, L. C., Groves, C. J., Grundberg, E., Guiducci, C., Hamsten, A., Han, B. G., Hara, K., Hassanali, N., Hattersley, A. T., Hayward, C., Hedman, A. K., Herder, C., Hofman, A., Holmen, O. L., Hovingh, K., Hreidarsson, A. B., Hu, C., Hu, F. B., Hui, J., Humphries, S. E., Hunt, S. E., Hunter, D. J., Hveem, K., Hydrie, Z. I., Ikegami, H., Illig, T., Ingelsson, E., Islam, M., Isomaa, B., Jackson, A. U., Jafar, T., James, A., Jia, W., Jöckel, K. H., Jonsson, A., Jowett, J. B. M., Kadowaki, T., Kang, H. M., Kanoni, S., Kao, W. H. L., Kathiresan, S., Kato, N., Katulanda, P., Keinanen-Kiukaanniemi, S. M., Kelly, A. M., Khan, H., Khaw, K. T., Khor, C. C., Kim, H. L., Kim, S., Kim, Y. J., Kinnunen, L., Klopp, N., Kong, A., Korpi-Hyövälti, E., Kowlessur, S., Kraft, P., Kravic, J., Kristensen, M. M., Krithika, S., Kumar, A., Kumate, J., Kuusisto, J., Kwak, S. H., Laakso, M., Lagou, V., Lakka, T. A., Langenberg, C., Langford, C., Lawrence, R., Leander, K., Lee, J. M., Lee, N. R., Li, M., Li, X., Li, Y., Liang, J., Liju, S., Lim, W. Y., Lind, L., Lindgren, C. M., Lindholm, E., Liu, C. T., Liu, J. J., Lobbens, S., Long, J., Loos, R. J. F., Lu, W., Luan, J., Lyssenko, V., WMa, R. C., Maeda, S., Mägi, R., Männistö, S., Matthews, D. R., Meigs, J. B., Melander, O., Metspalu, A., Meyer, J., Mirza, G., Mihailov, E., Moebus, S., Mohan, V., Mohlke, K. L., Morris, A. D., WMühleisen, T., Müller-Nurasyid, M., Musk, B., Nakamura, J., Nakashima, E., Navarro, P., Ng, P. K., Nica, A. C., Nilsson, P. M., Njølstad, I., Nöthen, M. M., Keizo, O., Ong, T. H., Owen, K. R., Palmer, C. N. A., Pankow, J. S., Park, K. S., Parkin, M., Pechlivanis, S., Pedersen, N. L., Peltonen, L., Perry, J. R. B., Peters, A., Pinidiyapathirage, J. M., Platou, C. G. P., Potter, S., Price, J. F., Qi, L., Radha, V., Rallidis, L., Rasheed, A., Rathmann, W., Rauramaa, R., Raychaudhuri, S., Rayner, N. W., Rees, S. D., Rehnberg, E., Ripatti, S., Robertson, N., Roden, M., Rossin, E. J., Rudan, I., Rybin, D., Saaristo, T. E., Salomaa, V., Saltevo, J., Samuel, M., KSanghera, D., Saramies, J., Scott, J., Scott, L. J., Scott, R. A., Segrè, A. V., Sehmi, J., Sennblad, B., Shah, N., Shah, S., Shera, A. S., Shu, X. O., Shuldiner, A. R., Sigurosson, G., Sijbrands, E., Silveira, A., Sim, X., Sivapalaratnam, S., Small, K. S., So, W. Y., Stančáková, A., Stefansson, K., Steinbach, G., Steinthorsdottir, V., Stirrups, K., Strawbridge, R. J., Stringham, H. M., Sun, Q., Suo, C., Syvänen, A. C., Takayanagi, R., Takeuchi, F., Tay, W. T., Teslovich, T. M., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Trakalo, J., Tremoli, E., Trip, M. D., Tsai, F. J., Tuomi, T., Tuomilehto, J., Uitterlinden, A. G., Valladares-Salgado, A., Vedantam, S., Veglia, F., Voight, B. F., Wang, C., Wareham, N. J., Wennauer, R., Wickremasinghe, A. R., Wilsgaard, T., Wilson, J. F., Wiltshire, S., Winckler, W., Wong, T. Y., Wood, A. R., Wu, J. Y., Wu, Y., Yamamoto, K., Yamauchi, T., Yang, M., Yengo, L., Yokota, M., Young, R., Zabaneh, D., Zhang, F., Zhang, R., Zheng, W., Zimmet, P. Z., Altshuler, D., Bowden, D. W., Cho, Y. S., Cox, N. J., Cruz, M., Hanis, C. L., Kooner, J., Lee, J. Y., Seielstad, M., Teo, Y. Y., Boehnke, M., Parra, E. J., Chambers, J. C., Tai, E. S., McCarthy, M. I. & Morris, A. P., Jan 1 2014, In : Nature genetics. 46, 3, p. 234-244 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Meta-Analysis
Genome
Genome-Wide Association Study
Single Nucleotide Polymorphism
7 Citations (Scopus)

Geometrical characteristics of left ventricular dyssynchrony in advanced heart failure: Myocardial strain analysis by tagged MRI

Nagao, M., Yamasaki, Y., Yonezawa, M., Kamitani, T., Kawanami, S., Mukai, Y., Higo, T., Yabuuchi, H., Sunagawa, K. & Honda, H., Jan 1 2014, In : International heart journal. 55, 6, p. 512-518 7 p.

Research output: Contribution to journalArticle

Heart Failure
Cine Magnetic Resonance Imaging
Logistic Models
Regression Analysis
Blood Pressure
48 Citations (Scopus)

Hedgehog signaling pathway as a new therapeutic target in pancreatic cancer

Ohnishi, H. & Katano, M., Jan 1 2014, In : World Journal of Gastroenterology. 20, 9, p. 2335-2342 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Therapeutics
Neoplastic Stem Cells
Morphogenesis
Neoplasms
31 Citations (Scopus)

Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer

Matsushita, S., Ohnishi, H., nakano, K., Nagamatsu, I., Imaizumi, A., Hattori, M., Oda, Y., Tanaka, M. & Katano, M., Jan 1 2014, In : Cancer Science. 105, 3, p. 272-280 9 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Therapeutics
Gallbladder
Matrix Metalloproteinases
Neoplasms
17 Citations (Scopus)

Image-guided placement of the Bonebridge™ without surgical navigation equipment

Cho, B., Matsumoto, N., Mori, M., Komune, S. & Hashizume, M., Sep 28 2014, In : International Journal of Computer Assisted Radiology and Surgery. 9, 5, p. 845-855 11 p.

Research output: Contribution to journalArticle

Surgical Equipment
Navigation
Perforators
Surgery
Bone
11 Citations (Scopus)

Intraoperative visualization of cerebral oxygenation using hyperspectral image data: a two-dimensional mapping method

Mori, M., Chiba, T., Nakamizo, A., Kumashiro, R., Murata, M., Akahoshi, T., Tomikawa, M., Kikkawa, Y., Yoshimoto, K., Mizoguchi, M., Sasaki, T. & Hashizume, M., Jan 1 2014, In : International Journal of Computer Assisted Radiology and Surgery. 9, 6, p. 1059-1072 14 p.

Research output: Contribution to journalArticle

Oxygenation
Visualization
Hemodynamics
Imaging techniques
Temporal Arteries
22 Citations (Scopus)
Bioprosthesis
Aortic Valve
Prostheses and Implants
Anticoagulants
Survival
10 Citations (Scopus)

Long-term study of subclinical Cushing’s syndrome shows high prevalence of extra-adrenal malignancy in patients with functioning bilateral adrenal tumors

Kawate, H., Kohno, M., matsuda, Y., Akehi, Y., Tanabe, M., Horiuchi, T., Keizo, O., Nomura, M., Yanase, T. & Takayanagi, R., Jan 1 2014, In : Endocrine Journal. 61, 12, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

Glandular and Epithelial Neoplasms
Cushing Syndrome
Neoplasms
Hydrocortisone
Diabetes Mellitus
9 Citations (Scopus)

Mass spectrometry-based metabolic profiling of gemcitabine-sensitive and gemcitabine-resistant pancreatic cancer cells

Fujimura, Y., Ikenaga, N., Ouchida, K., Setoyama, D., Irie, M., Miura, D., Wariishi, H., Murata, M., Mizumoto, K., Hashizume, M. & Tanaka, M., Mar 1 2014, In : Pancreas. 43, 2, p. 311-318 8 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Mass Spectrometry
Cell Line
Metabolome
3 Citations (Scopus)

Merits of prophylactic sclerotherapy for esophageal varices concomitant unresectable hepatocellular carcinoma: Prospective randomized study

Akahoshi, T., Tomikawa, M., Tsutsumi, N., Hashizume, M. & Maehara, Y., Jan 1 2014, In : Digestive Endoscopy. 26, 2, p. 172-177 6 p.

Research output: Contribution to journalArticle

Sclerotherapy
Esophageal and Gastric Varices
Hepatocellular Carcinoma
Prospective Studies
Injections

Minimally invasive image analysis of biliary-pancreatic structure for preoperative simulation

Maeda, T., Konishi, K., Tanoue, K., Taketomi, A., Shirabe, K., Maehara, Y. & Hashizume, M., Jan 1 2014, In : Hepato-gastroenterology. 61, 134, p. 1744-1747 4 p.

Research output: Contribution to journalArticle

Multidetector Computed Tomography
Pancreatic Ducts
Neoplasms
10 Citations (Scopus)

More than 20-year experience of Bentall operation with mechanical prostheses for chronic aortic root aneurysm

Nishida, T., Sonoda, H., Oishi, Y., Ushijima, T., Tanoue, Y., Nakashima, A., Shiokawa, Y. & Tominaga, R., Jan 1 2014, In : General thoracic and cardiovascular surgery. 63, 2, p. 78-85 8 p.

Research output: Contribution to journalArticle

Aortic Aneurysm
Prostheses and Implants
Rupture
Aortic Valve Insufficiency
Hospital Mortality
34 Citations (Scopus)

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

Chen, P., Takeuchi, F., Lee, J. Y., Li, H., Wu, J. Y., Liang, J., Long, J., Tabara, Y., Goodarzi, M. O., Pereira, M. A., Kim, Y. J., Go, M. J., Stram, D. O., Vithana, E., Khor, C. C., Liu, J., Liao, J., Ye, X., Wang, Y., Lu, L. & 50 others, Young, T. L., Lee, J., Thai, A. C., Cheng, C. Y., Van Dam, R. M., Friedlander, Y., Heng, C. K., Koh, W. P., Chen, C. H., Chang, L. C., Pan, W. H., Qi, B., Isono, M., Zheng, W., Cai, Q., Gao, Y., Yamamoto, K., Keizo, O., Takayanagi, R., Kita, Y., Ueshima, H., Hsiung, C. A., Cui, J., Sheu, W. H. H., Rotter, J. I., Chen, Y. D. I., Hsu, C., Okada, Y., Kubo, M., Takahashi, A., Tanaka, T., Van Rooij, F. J. A., Ganesh, S. K., Huang, J., Huang, T., Yuan, J., Hwang, J. Y., Gross, M. D., Assimes, T. L., Miki, T., Shu, X. O., Qi, L., Chen, Y. T., Lin, X., Aung, T., Wong, T. Y., Teo, Y. Y., Kim, B. J., Kato, N. & Tai, E. S., Jan 1 2014, In : Diabetes. 63, 7, p. 2551-2562 12 p.

Research output: Contribution to journalArticle

Glycosylated Hemoglobin A
Hemoglobins
Genome-Wide Association Study
Meta-Analysis
Glucose
20 Citations (Scopus)

NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors

Morisaki, T., Hirano, T., Koya, N., Kiyota, A., Tanaka, H., Umebayashi, M., Ohnishi, H. & Katano, M., Aug 1 2014, In : Anticancer research. 34, 8, p. 4529-4538 10 p.

Research output: Contribution to journalArticle

gemcitabine
Lymphocytes
Cytokines
Neoplasms
Therapeutics
1 Citation (Scopus)

Non-cirrhotic portal-systemic encephalopathy caused by enlargement of a splenorenal shunt after pancreaticoduodenectomy for locally advanced duodenal cancer: Report of a case

Kasagi, Y., Saeki, H., Akahoshi, T., Kawasaki, J., Andou, K., Oki, E., Ohga, T., Tomikawa, M., Kakeji, Y., Shirabe, K. & Maehara, Y., Jan 1 2014, In : Surgery today. 44, 8, p. 1573-1576 4 p.

Research output: Contribution to journalArticle

Duodenal Neoplasms
Surgical Splenorenal Shunt
Pancreaticoduodenectomy
Hepatic Encephalopathy
Consciousness
25 Citations (Scopus)

NOTCH4 is a potential therapeutic target for triple-negative breast cancer

Nagamatsu, I., Ohnishi, H., Matsushita, S., Kubo, M., Kai, M., Imaizumi, A., nakano, K., Hattori, M., Oda, Y., Tanaka, M. & Katano, M., Jan 1 2014, In : Anticancer research. 34, 1, p. 69-80 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Therapeutics
Small Interfering RNA
Cell Proliferation
Tumor Burden
24 Citations (Scopus)

Optimizing risk stratification in portal vein thrombosis after splenectomy and its primary prophylaxis with antithrombin III concentrates and danaparoid sodium in liver cirrhosis with portal hypertension

Kawanaka, H., Akahoshi, T., itoh, S., Iguchi, T., Harimoto, N., Uchiyama, H., Yoshizumi, T., Shirabe, K., Takenaka, K. & Maehara, Y., Nov 1 2014, In : Journal of the American College of Surgeons. 219, 5, p. 865-874 10 p.

Research output: Contribution to journalArticle

Antithrombin III
Portal Hypertension
Splenectomy
Portal Vein
Liver Cirrhosis
2 Citations (Scopus)

Perioperative sequential monitoring of hemodynamic parameters in patients with pheochromocytoma using the Non-Invasive Cardiac System (NICaS)

matsuda, Y., Kawate, H., Shimada, S., Matsuzaki, C., Nagata, H., Adachi, M., Keizo, O., Nomura, M. & Takayanagi, R., Jan 1 2014, In : Endocrine Journal. 61, 6, p. 571-575 5 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Blood Volume
Cardiac Output
Hemodynamics
Serum Albumin
18 Citations (Scopus)

Physician presence in an ambulance car is associated with increased survival in out-of-hospital cardiac arrest: A prospective cohort analysis

Hagihara, A., Hasegawa, M., Abe, T., Nagata, T. & Nabeshima, Y., Jan 8 2014, In : PloS one. 9, 1, e84424.

Research output: Contribution to journalArticle

Ambulance cars
Out-of-Hospital Cardiac Arrest
cardiac arrest
Ambulances
physicians
3 Citations (Scopus)

Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Suma, S., Sasakabe, T., Hamajima, N., Hosono, S., Horita, M., Turin, T. C., Suzuki, S., Kairupan, T. S., Mikami, H., Keizo, O., Watanabe, I., Uemura, H., Kubo, M. & Tanaka, H., Oct 14 2014, In : Lipids in Health and Disease. 13, 1, 162.

Research output: Contribution to journalArticle

Polymorphism
Chronic Renal Insufficiency
Lipid Metabolism
Japan
Cohort Studies
2 Citations (Scopus)

Preliminary in vivo evaluation of a needle insertion manipulator for central venous catheterization

Kobayashi, Y., Hamano, R., Watanabe, H., Koike, T., Hong, J., Toyoda, K., Uemura, M., Ieiri, S., Tomikawa, M., Ohdaira, T., Hashizume, M. & Fujie, M. G., Nov 16 2014, In : Afrika Matematika. 1, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Manipulator
Skin
Insertion
Evaluation
Stick-slip

Preloading based needle insertion with a concave probe to enhance targeting in breast tissue

Kobayashi, Y., Hatano, M., Suzuki, M., Shiraishi, Y., Yambe, T., Hashizume, M. & Fujie, M. G., Dec 1 2014, In : ROBOMECH Journal. 1, 1, 17.

Research output: Contribution to journalArticle

prestressing
needles
breast
Needles
Insertion
CCAAT-Enhancer-Binding Proteins
Monoclonal Antibodies
Protein Isoforms
Leucine Zippers
DNA
4 Citations (Scopus)

Prognostic significance of urine N1,N12-diacetylspermine in patients with non-small cell lung cancer

Kato, M., Ohnishi, H., Matsumoto, K., Motoshita, J., Tsuruta, N., Higuchi, K. & Katano, M., Jan 1 2014, In : Anticancer research. 34, 6, p. 3053-3060 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Urine
Recurrence
Survival
N',N''-diacetylspermine
14 Citations (Scopus)

Quantification of myocardial iron deficiency in nonischemic heart failure by cardiac T2* magnetic resonance imaging

Nagao, M., Matsuo, Y., Kamitani, T., Yonezawa, M., Yamasaki, Y., Kawanami, S., Abe, K., Mukai, Y., Higo, T., Yabuuchi, H., Takemura, A., Yoshiura, T., Sunagawa, K. & Honda, H., Mar 15 2014, In : American Journal of Cardiology. 113, 6, p. 1024-1030 7 p.

Research output: Contribution to journalArticle

Iron
Heart Failure
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Biomarkers
19 Citations (Scopus)

Quantitative assessment of right ventricular function and pulmonary regurgitation in surgically repaired tetralogy of Fallot using 256-slice CT: comparison with 3-Tesla MRI

Yamasaki, Y., Nagao, M., Yamamura, K., Yonezawa, M., Matsuo, Y., Kawanami, S., Kamitani, T., Higuchi, K., Sakamoto, I., Shiokawa, Y., Yabuuchi, H. & Honda, H., Nov 14 2014, In : European Radiology. 24, 12, p. 3289-3299 11 p.

Research output: Contribution to journalArticle

Pulmonary Valve Insufficiency
Right Ventricular Function
Tetralogy of Fallot
Tomography
Magnetic Resonance Spectroscopy
2 Citations (Scopus)

Random migration contributes to cytotoxicity of activated CD8+ T-lymphocytes but not NK cells

Ohnishi, H., Kiyota, A., Koya, N., Tanaka, H., Umebayashi, M., Katano, M. & Morisaki, T., Aug 1 2014, In : Anticancer research. 34, 8, p. 3947-3956 10 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Lymphocytes
T-Lymphocytes
Time-Lapse Imaging
Lysosphingolipid Receptors