Research Output 1984 2019

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2016
1 Citation (Scopus)
Cardiomyopathies
Myocardium
Electron Microscopy
Mitochondria
141 Citations (Scopus)

Guía ESC 2016 sobre el diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica

Translated title of the contribution: 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failurePonikowski, AM. D. G. D. T. P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., Falk, V., González-Juanatey, J. R., Harjola, V. P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M. C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H. & 43 others, van der Meer, P., Filippatos, R. D. D. G., McMurray, J. J. V., Aboyans, V., Achenbach, S., Agewall, S., Al-Attar, N., James Atherton, J., Bauersachs, J., Camm, A. J., Carerj, S., Ceconi, C., Coca, A., Elliott, P., Erol, Ç., Ezekowitz, J., Fernández-Golfín, C., Fitzsimons, D., Guazzi, M., Guenoun, M., Hasenfuss, G., Hindricks, G., Hoes, A. W., Iung, B., Jaarsma, T., Kirchhof, P., Knuuti, J., Kolh, P., Konstantinides, S., Lainscak, M., Lancellotti, P., Lip, G. Y. H., Maisano, F., Mueller, C., Petrie, M. C., Piepoli, M. F., Priori, S. G., Torbicki, A., Tsutsui, H., van Veldhuisen, D. J., Windecker, S., Yancy, C. & Zamorano, J. L., Dec 1 2016, In : Revista Espanola de Cardiologia. 69, 12, p. 1167.-1167.

Research output: Contribution to journalArticle

10 Citations (Scopus)
ivabradine
Heart Rate
Placebos
Heart Failure
Phosphenes
Acute Coronary Syndrome
Registries
Hemoglobins
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Platelet Aggregation Inhibitors
11 Citations (Scopus)

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease

Oka, S., Leon, J., Kunihiko, S., Ide, T., Kang, D., LaFerla, F. M. & Nakabeppu, Y., Nov 29 2016, In : Scientific reports. 6, 37889.

Research output: Contribution to journalArticle

Alzheimer Disease
Mitochondria
Prealbumin
Mitochondrial DNA
Oxidative Stress
2 Citations (Scopus)

Incidental focal myocardial 18F-FDG uptake indicating asymptomatic coronary artery disease

Aikawa, T., Naya, M., Manabe, O., Obara, M., Matsushima, S., Tamaki, N. & Tsutsui, H., Jun 1 2016, In : Journal of Nuclear Cardiology. 23, 3, p. 596-598 3 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Coronary Artery Disease

Long-term echocardiographic evaluation of valvular lesions in a patient with nonbacterial thrombotic endocarditis associated with advanced uterine cancer

Yokoyama, S., Iwano, H., Yamada, S., Takeda, M., Kaga, S., Nakabachi, M., Nishino, H., Ichikawa, A., Abe, A., Okada, K., Murai, D., Hayashi, T., Nishida, M., Shibuya, H., Kahata, K., Shimizu, C., Mikami, T. & Tsutsui, H., Sep 1 2016, In : Journal of Cardiology Cases. 14, 3, p. 82-86 5 p.

Research output: Contribution to journalArticle

Uterine Neoplasms
Endocarditis
Echocardiography
Heart Valves
Mitral Valve Insufficiency
15 Citations (Scopus)

Long-term effect of sitagliptin on endothelial function in type 2 diabetes: A sub-analysis of the PROLOGUE study

for the PROLOGUE Study Investigators, Sep 13 2016, In : Cardiovascular Diabetology. 15, 1, 134.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Brachial Artery
Hypoglycemic Agents
Dipeptidyl-Peptidase IV Inhibitors
Information Centers
4 Citations (Scopus)

Myocardial immunocompetent cells and macrophage phenotypes as histopathological surrogates for diagnosis of cardiac sarcoidosis in Japanese

Honda, Y., Nagai, T., Ikeda, Y., Sakakibara, M., Asakawa, N., Nagano, N., Nakai, M., Nishimura, K., Sugano, Y., Ohta-Ogo, K., Asaumi, Y., Aiba, T., Kanzaki, H., Kusano, K., Noguchi, T., Yasuda, S., Tsutsui, H., Ishibashi-Ueda, H. & Anzai, T., Nov 1 2016, In : Journal of the American Heart Association. 5, 11, e004019.

Research output: Contribution to journalArticle

Sarcoidosis
Macrophages
Phenotype
Dendritic Cells
Granuloma
2 Citations (Scopus)

Optical Frequency Domain Imaging of Covered Stent-Graft for Pulmonary Artery Pseudoaneurysm After Balloon Pulmonary Angioplasty

Horimoto, K., Abe, K., ohtani, K., Takahara, Y., Hosokawa, K., Oi, K., Mukai, Y., Kubo, T., Matoba, T. & Tsutsui, H., Nov 14 2016, In : JACC: Cardiovascular Interventions. 9, 21, p. 2255-2256 2 p.

Research output: Contribution to journalArticle

Balloon Angioplasty
False Aneurysm
Pulmonary Artery
Stents
Aneurysm
10 Citations (Scopus)

Optimal Titration Is Important to Maximize the Beneficial Effects of Vagal Nerve Stimulation in Chronic Heart Failure

Nishizaki, A., Sakamoto, K., Saku, K., Hosokawa, K., sakamoto, T., Oga, Y., Akashi, T., Murayama, Y., Kishi, T., Ide, T. & Sunagawa, K., Aug 1 2016, In : Journal of Cardiac Failure. 22, 8, p. 631-638 8 p.

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Heart Failure
Myocardial Infarction
Nerve Fibers
Stroke Volume
4 Citations (Scopus)

Prediction of contrast-induced nephropathy by the serum creatinine level on the day following cardiac catheterization

CINC-J study investigators, Nov 1 2016, In : Journal of Cardiology. 68, 5, p. 412-418 7 p.

Research output: Contribution to journalArticle

Cardiac Catheterization
Glomerular Filtration Rate
Creatinine
Serum
Area Under Curve
13 Citations (Scopus)

Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: Results from the MAGGIC individual patient data meta-analysis

Berry, C., Poppe, K. K., Gamble, G. D., Earle, N. J., Ezekowitz, J. A., Squire, I. B., McMurray, J. J. V., McAlister, F. A., Komajda, M., Swedberg, K., Maggioni, A. P., Ahmed, A., Whalley, G. A., Doughty, R. N., Tarantini, L., Granger, C., Køber, L., Massie, B., Pocock, S., Somaratne, J. & 147 others, Andersson, B., Bayes-Genis, A., Cowie, M., Cubbon, R., Gonzalez-Juanatey, J., Gorini, M., Gotsman, I., Grigorian-Shamagian, L., Guazzi, M., Kearney, M., Di Lenarda, A., Lenzen, M., Lucci, D., Macín, S., Madsen, B., Martínez-Sellés, M., Oliva, F., Rich, M., Richards, M., Senni, M., Taffet, G., Tribouilloy, C., Troughton, R., Tsutsui, H., Ariti, C., Dobson, J., Hall, C., Lainchbury, J., Hogg, K., Norrie, J., Stevenson, K., Brett, M., Pfeffer, M. A., Held, P., Michelson, E. L., Olofsson, B., Östergren, J., Yusuf, S., Torp-Pedersen, C., Scholte op Reimer, W., Boersma, E., Vantrimpont, P. J. M. J., Follath, F., Cleland, J., Zwas, D., Planer, D., Azaz-Livshits, T., Admon, D., Lotan, C., Keren, A., Varela-Roman, A., Mazón-Ramos, P., Rigeiro-Veloso, P., Bandin-Dieguez, M. A., Myers, J., Arena, R., Armstrong, P. W., Cujec, B., Paterson, I., Wood, D. A., Coats, A. J. S., Thompson, S. G., Suresh, V., Poole-Wilson, P. A., Sutton, G. C., Robles, J. A. G., Prieto, L., Muñoa, M. D., Frades, E., Díaz-Castro, O., Almendral, J., Faggiano, P., Bertoli, D., Porcu, M., Opasich, C., Tavazzi, L., Kirk, V., Bay, M., Parner, J., Krogsgaard, K., Herzog, T. M., Boesgaard, S., Hassager, C., Nielsen, O. W., Aldershvile, J., Nielsen, H., Kober, L., Perna, E. R., Cimbaro Canella, J. P., Alvarenga, P., Pantich, R., Ríos, N., Farias, E. F., Badaracco, J. R., Hansen, J. F., Stokholm, K. H., Brons, J., Husum, D., Mortensen, L. S., Vazquez, R., Puig, T., Fernandez-Palomeque, C., Bardají, A., Pascual-Figal, D., Ordoñez-Llanos, J., Valdes, M., Gabarrus, A., Pavon, R., Pastor, L., Fiol, M., Nieto, V., Macaya, C., Cinca, J., Cygankiewitz, I., Bayes De Luna, A., Newton, J. D., Blackledge, H. M., Wright, S. P., Kerzner, R., Gage, B. F., Freedland, K. E., Huynh, B. C., Rovner, A., Carney, R. M., Teasdale, T. A., Bleyer, A. J., Kutka, N. J., Luchi, R. J., Rusinaru, D., Mahjoub, H., Soulière, V., Lévy, F., Peltier, M., Tsuchihashi, M., Takeshita, A., MacCarthy, P. A., Nolan, J., Lee, A. J., Prescott, R. J., Shah, A. M., Brooksby, W. P., Fox, K. A. A., Basante, P., Trillo, R., Garcia-Seara, J., Martinez-Sande, J. L. & Gude, F., Jan 1 2016, In : QJM. 109, 6, p. 377-382 6 p.

Research output: Contribution to journalArticle

Meta-Analysis
Anemia
Heart Failure
Hemoglobins
Glomerular Filtration Rate
2 Citations (Scopus)

Pulmonary arterial hypertension associated with hereditary hemorrhagic telangiectasia successfully treated with sildenafil

Miyake, R., Fujino, T., Abe, K., Hosokawa, K., Ohtani, K., Morisaki, H., Yamada, O., Higo, T. & Ide, T., Jul 1 2016, In : International Journal of Cardiology. 214, p. 275-276 2 p.

Research output: Contribution to journalArticle

Type II Activin Receptors
Hereditary Hemorrhagic Telangiectasia
Telangiectasis
Missense Mutation
Pedigree
28 Citations (Scopus)

Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension

Nishimura, A., Sunggip, C., Saitoh, H., Shimauchi, T., Numaga-Tomita, T., Hirano, K., Ide, T., Boeynaems, J. M., Kurose, H., Makoto, T., Robaye, B., Inoue, K. & Nishida, M., Jan 19 2016, In : Science Signaling. 9, 411, aac9187.

Research output: Contribution to journalArticle

Purinergic Receptors
Angiotensin Type 1 Receptor
Angiotensin II
Hypertension
Arrestin
11 Citations (Scopus)

Serum myostatin levels are independently associated with skeletal muscle wasting in patients with heart failure

Furihata, T., Kinugawa, S., Fukushima, A., Takada, S., Homma, T., Masaki, Y., Abe, T., Yokota, T., Oba, K., Okita, K. & Tsutsui, H., Oct 1 2016, In : International Journal of Cardiology. 220, p. 483-487 5 p.

Research output: Contribution to journalArticle

Myostatin
Skeletal Muscle
Heart Failure
Serum
Muscles
30 Citations (Scopus)

The current status of cardiovascular medicine in Japan – Analysis of a large number of health records from a nationwide claim-based database, JROAD-DPC

JROAD Investigators, Jan 1 2016, In : Circulation Journal. 80, 11, p. 2327-2335 9 p.

Research output: Contribution to journalArticle

Japan
Medicine
Databases
Heart Failure
Angiotensin Receptor Antagonists
10 Citations (Scopus)

The experimental model of transition from compensated cardiac hypertrophy to failure created by transverse aortic constriction in mice

Furihata, T., Kinugawa, S., Takada, S., Fukushima, A., Takahashi, M., Homma, T., Masaki, Y., Tsuda, M., Matsumoto, J., Mizushima, W., Matsushima, S., Yokota, T. & Tsutsui, H., Jun 1 2016, In : IJC Heart and Vasculature. 11, p. 24-28 5 p.

Research output: Contribution to journalArticle

Cardiomegaly
Constriction
Theoretical Models
Left Ventricular Hypertrophy
Ventricular Remodeling
11 Citations (Scopus)

Total mechanical unloading minimizes metabolic demand of left ventricle and dramatically reduces infarct size in myocardial infarction

Saku, K., Kakino, T., Arimura, T., sakamoto, T., Nishikawa, T., Sakamoto, K., Ikeda, M., Kishi, T., Ide, T. & Sunagawa, K., Apr 1 2016, In : PloS one. 11, 4, e0152911.

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
infarction
myocardial infarction
Unloading
18 Citations (Scopus)

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis

Numaga-Tomita, T., Kitajima, N., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., Dec 19 2016, In : Scientific reports. 6, 39383.

Research output: Contribution to journalArticle

Cardiac Myocytes
Fibrosis
Microtubules
Pressure
Fibroblasts
31 Citations (Scopus)

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Kitajima, N., Numaga-Tomita, T., Watanabe, M., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., Nov 11 2016, In : Scientific reports. 6, 37001.

Research output: Contribution to journalArticle

NADPH Oxidase
Reactive Oxygen Species
Physiological Adaptation
Proteasome Endopeptidase Complex
Cardiac Myocytes
7 Citations (Scopus)

Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis

Inoue, T., Ikeda, M., Ide, T., Fujino, T., Matsuo, Y., Arai, S., Saku, K. & Sunagawa, K., Sep 1 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 3, p. H509-H519

Research output: Contribution to journalArticle

Heart Rupture
Organelle Biogenesis
Mitochondrial DNA
Myocardial Infarction
Matrix Metalloproteinases
25 Citations (Scopus)

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling

Matsushima, S., Kuroda, J., Zhai, P., Liu, T., Ikeda, S., Nagarajan, N., Oka, S. I., Yokota, T., Kinugawa, S., Hsu, C. P., Li, H., Tsutsui, H. & Sadoshima, J., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3403-3416 14 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Protein-Tyrosine Kinases
Cell Death
Apoptosis
Ventricular Remodeling
12 Citations (Scopus)

Value of virtual touch quantification elastography for assessing liver congestion in patients with heart failure

Yoshitani, T., Asakawa, N., Sakakibara, M., Noguchi, K., Tokuda, Y., Kamiya, K., Iwano, H., Yamada, S., Kudou, Y., Nishida, M., Shimizu, C., Amano, T. & Tsutsui, H., Jan 1 2016, In : Circulation Journal. 80, 5, p. 1187-1195 9 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Touch
Heart Failure
Liver
Central Venous Pressure
2015
15 Citations (Scopus)
secretin
glucagon-like peptide 1
Incretins
Glucagon-Like Peptide 1
glycohemoglobin
46 Citations (Scopus)

Adaptive servo-ventilation therapy for patients with chronic heart failure in a confirmatory, multicenter, randomized, controlled study

SAVIOR-C Investigators, Jan 1 2015, In : Circulation Journal. 79, 5, p. 982-990 9 p.

Research output: Contribution to journalArticle

Ventilation
Heart Failure
Stroke Volume
Brain Natriuretic Peptide
Guidelines
23 Citations (Scopus)

Angiotensin II can directly induce mitochondrial dysfunction, decrease oxidative fibre number and induce atrophy in mouse hindlimb skeletal muscle

Kadoguchi, T., Kinugawa, S., Takada, S., Fukushima, A., Furihata, T., Homma, T., Masaki, Y., Mizushima, W., Nishikawa, M., Takahashi, M., Yokota, T., Matsushima, S., Okita, K. & Tsutsui, H., Mar 1 2015, In : Experimental Physiology. 100, 3, p. 312-322 11 p.

Research output: Contribution to journalArticle

Hindlimb
Angiotensin II
Atrophy
Skeletal Muscle
Citrate (si)-Synthase
19 Citations (Scopus)

Changes in vascular properties, not ventricular properties, predominantly contribute to baroreflex regulation of arterial pressure

sakamoto, T., Kakino, T., Sakamoto, K., Tobushi, T., Tanaka, A., Saku, K., Hosokawa, K., Onitsuka, K., Murayama, Y., Tsutsumi, T., Ide, T. & Sunagawa, K., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 1, p. H49-H58

Research output: Contribution to journalArticle

Baroreflex
Carotid Sinus
Blood Vessels
Arterial Pressure
Pressure
1 Citation (Scopus)

Characteristics of inoperable patients with severe aortic valve stenosis—in the era of transcatheter aortic valve replacement

Seki, T., Sakakibara, M., Shingu, Y., Katoh, H., Wakasa, S., Tsutsui, H. & Matsui, Y., Jan 1 2015, In : Annals of Thoracic and Cardiovascular Surgery. 21, 2, p. 132-138 7 p.

Research output: Contribution to journalArticle

Aortic Valve
Aortic Valve Stenosis
Japan
Age Groups
Transcatheter Aortic Valve Replacement
9 Citations (Scopus)

Critical takotsubo cardiomyopathy complicated by ventricular septal perforation

Aikawa, T., Sakakibara, M., Takahashi, M., Asakawa, K., Dannoura, Y., Makino, T., Koya, T. & Tsutsui, H., Jan 1 2015, In : Internal Medicine. 54, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Ventricular Septal Rupture
Takotsubo Cardiomyopathy
Electrocardiography
Cardiogenic Shock
Coronary Stenosis
26 Citations (Scopus)

Curcumin ameliorates skeletal muscle atrophy in type 1 diabetic mice by inhibiting protein ubiquitination

Ono, T., Takada, S., Kinugawa, S. & Tsutsui, H., Sep 1 2015, In : Experimental Physiology. 100, 9, p. 1052-1063 12 p.

Research output: Contribution to journalArticle

Curcumin
Muscular Atrophy
Ubiquitination
Skeletal Muscle
Diabetes Mellitus
5 Citations (Scopus)

Establishment of a two-dimensional chiral HPLC system for the simultaneous detection of lactate and 3-hydroxybutyrate enantiomers in human clinical samples

Liu, S. L., Oyama, T., Miyoshi, Y., Sheu, S. Y., Mita, M., Ide, T., Lindner, W., Hamase, K. & Lee, J. A., Dec 10 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 116, p. 80-85 6 p.

Research output: Contribution to journalArticle

3-Hydroxybutyric Acid
Enantiomers
Lactic Acid
High Pressure Liquid Chromatography
formic acid
23 Citations (Scopus)

European Heart Rhythm Association/Heart Failure Association joint consensus document on arrhythmias in heart failure, endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society

Lip, G. Y. H., Heinzel, F. R., Gaita, F., Juanatey, J. R. G., Le Heuzey, J. Y., Potpara, T., Svendsen, J. H., Vos, M. A., Anker, S. D., Coats, A. J., Haverkamp, W., Manolis, A. S., Chung, M. K., Sanders, P., Pieske, B., Gorenek, B., Lane, D., Boriani, G., Linde, C., Hindricks, G. & 9 others, Tsutsui, H., Homma, S., Brownstein, S., Nielsen, J. C., Lainscak, M., Crespo-Leiro, M., Piepoli, M., Seferovic, P. & Savelieva, I., Dec 28 2015, In : Europace. 18, 1, p. 12-36 25 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Myocardial shortening in 3 orthogonal directions and its transmural variation in patients with nonobstructive hypertrophic cardiomyopathy

Okada, K., Yamada, S., Iwano, H., Nishino, H., Nakabachi, M., Yokoyama, S., Abe, A., Ichikawa, A., Kaga, S., Nishida, M., Hayashi, T., Murai, D., Mikami, T. & Tsutsui, H., Oct 23 2015, In : Circulation Journal. 79, 11, p. 2471-2479 9 p.

Research output: Contribution to journalArticle

Hypertrophic Cardiomyopathy
Stroke Volume
Echocardiography
Maintenance
Direction compound
49 Citations (Scopus)

Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress

Ikeda, M., Ide, T., Fujino, T., Arai, S., Saku, K., Kakino, T., Tyynismaa, H., Yamasaki, T., Yamada, K. I., Kang, D., Suomalainen, A. & Sunagawa, K., Mar 30 2015, In : PloS one. 10, 3, e0119687.

Research output: Contribution to journalArticle

Mitochondria
Oxidative stress
Mitochondrial DNA
reactive oxygen species
Reactive Oxygen Species

Pharmacotherapy of hypertrophic cardiomyopathy

Tsutsui, H., Jul 1 2015, In : Respiration and Circulation. 63, 7, p. 623-629 7 p.

Research output: Contribution to journalArticle

Hypertrophic Cardiomyopathy
Drug Therapy
7 Citations (Scopus)

Prediction of adverse cardiac events in dilated cardiomyopathy using cardiac T2* MRI and MIBG scintigraphy

Nagao, M., Baba, S., Yonezawa, M., Yamasaki, Y., Kamitani, T., Isoda, T., Kawanami, S., Maruoka, Y., Kitamura, Y., Abe, K., Higo, T., Sunagawa, K. & Honda, H., Feb 27 2015, In : International Journal of Cardiovascular Imaging. 31, 2, p. 399-407 9 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Radionuclide Imaging
Iron
Ventricular Septum
ROC Curve
7 Citations (Scopus)

Prediction of the impact of venoarterial extracorporeal membrane oxygenation on hemodynamics

Sakamoto, K., Saku, K., Kishi, T., Kakino, T., Tanaka, A., sakamoto, T., Ide, T. & Sunagawa, K., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 8, p. H921-H930

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Hemodynamics
Atrial Pressure
Cardiac Output
Right Ventricular Function
5 Citations (Scopus)

Predictors and proarrhythmic consequences of inappropriate implantable cardioverter-defibrillator therapy

Tenma, T., Yokoshiki, H., Mizukami, K., Mitsuyama, H., Watanabe, M., Sasaki, R., Maeno, M., Matsui, Y. & Tsutsui, H., Aug 25 2015, In : Circulation Journal. 79, 9, p. 1920-1927 8 p.

Research output: Contribution to journalArticle

Implantable Defibrillators
Shock
Confidence Intervals
Therapeutics
Diuretics
8 Citations (Scopus)

Proteinuria and reduced estimated glomerular filtration rate are independent risk factors for contrast-induced nephropathy after cardiac catheterization

CINC-J study investigators, Jun 9 2015, In : Circulation Journal. 79, 7, p. 1624-1630 7 p.

Research output: Contribution to journalArticle

Cardiac Catheterization
Glomerular Filtration Rate
Proteinuria
Incidence
Japan
8 Citations (Scopus)

Relation Between Dabigatran Concentration, as Assessed Using the Direct Thrombin Inhibitor Assay, and Activated Clotting Time/Activated Partial Thromboplastin Time in Patients With Atrial Fibrillation

Okubo, K., Kuwahara, T., Takagi, K., Takigawa, M., Nakajima, J., Watari, Y., Nakashima, E., Yamao, K., Fujino, T., Tsutsui, H. & Takahashi, A., Jun 15 2015, In : American Journal of Cardiology. 115, 12, p. 1696-1699 4 p., 21051.

Research output: Contribution to journalArticle

Antithrombins
Partial Thromboplastin Time
Atrial Fibrillation
Verapamil
Dabigatran

Role of mitochondria and reactive oxygen species in heart failure

Ide, T., Jul 1 2015, In : Japanese Journal of Clinical Chemistry. 44, 3, p. 191-197 7 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Mitochondria
Heart Failure
10 Citations (Scopus)

Serum brain-derived neurotropic factor level predicts adverse clinical outcomes in patients with heart failure

Fukushima, A., Kinugawa, S., Homma, T., Masaki, Y., Furihata, T., Yokota, T., Matsushima, S., Takada, S., Kadoguchi, T., Oba, K., Okita, K. & Tsutsui, H., Apr 1 2015, In : Journal of Cardiac Failure. 21, 4, p. 300-306 7 p.

Research output: Contribution to journalArticle

Heart Failure
Brain
Serum
Anaerobic Threshold
Carbon Dioxide
11 Citations (Scopus)

Sesamin prevents decline in exercise capacity and impairment of skeletal muscle mitochondrial function in mice with high-fat diet-induced diabetes

Takada, S., Kinugawa, S., Matsushima, S., Takemoto, D., Furihata, T., Mizushima, W., Fukushima, A., Yokota, T., Ono, Y., Shibata, H., Okita, K. & Tsutsui, H., Nov 1 2015, In : Experimental Physiology. 100, 11, p. 1319-1330 12 p.

Research output: Contribution to journalArticle

High Fat Diet
Skeletal Muscle
NADPH Oxidase
Diet
Superoxides
10 Citations (Scopus)

Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats

Mizukami, K., Yokoshiki, H., Mitsuyama, H., Watanabe, M., Tenma, T., Takada, S. & Tsutsui, H., Sep 18 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 6, p. H1066-H1074

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Cardiomegaly
Inbred SHR Rats
Phosphorylation
Apamin
11 Citations (Scopus)

The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload

Ikeda, M., Ide, T., Fujino, T., Matsuo, Y., Arai, S., Saku, K., Kakino, T., Oga, Y., Nishizaki, A. & Sunagawa, K., Oct 30 2015, In : Scientific reports. 5, 15881.

Research output: Contribution to journalArticle

Sirolimus
Hypertrophy
Blood Pressure
Cardiomegaly
Cardiac Output
2014
29 Citations (Scopus)

Afferent vagal nerve stimulation resets baroreflex neural arc and inhibits sympathetic nerve activity

Saku, K., Kishi, T., Sakamoto, K., Hosokawa, K., sakamoto, T., Murayama, Y., Kakino, T., Ikeda, M., Ide, T. & Sunagawa, K., Jan 1 2014, In : Physiological Reports. 2, 9, e12136.

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Baroreflex
Arterial Pressure
Splanchnic Nerves
Carotid Sinus
15 Citations (Scopus)

Assessment of quality of life during long-term treatment of tolvaptan in refractory heart failure: Design and rationale of the AQUA-TLV study

Imamura, T., Kinugawa, K., Ohtani, T., Sakata, Y., Higo, T., Kinugawa, S., Tsutsui, H., Sunagawa, K. & Komuro, I., 2014, In : International heart journal. 55, 3, p. 264-267 4 p.

Research output: Contribution to journalArticle

Heart Failure
Quality of Life
Japan
Therapeutics
Furosemide
15 Citations (Scopus)

Cardiac magnetic resonance performs better in the detection of functionally significant coronary artery Stenosis compared to single-photon emission computed Tomography and Dobutamine stress echocardiography

Kamiya, K., Sakakibara, M., Asakawa, N., Yamada, S., Yoshitani, T., Iwano, H., Komatsu, H., Naya, M., Chiba, S., Yamada, S., Manabe, O., Kikuchi, Y., Oyama-Manabe, N., Oba, K. & Tsutsui, H., Jan 1 2014, In : Circulation Journal. 78, 10, p. 2468-2476 9 p.

Research output: Contribution to journalArticle

Stress Echocardiography
Myocardial Perfusion Imaging
Coronary Stenosis
Single-Photon Emission-Computed Tomography
Magnetic Resonance Spectroscopy
15 Citations (Scopus)

Combination of exercise training and diet restriction normalizes limited exercise capacity and impaired skeletal muscle function in diet-induced diabetic mice

Suga, T., Kinugawa, S., Takada, S., Kadoguchi, T., Fukushima, A., Homma, T., Masaki, Y., Furihata, T., Takahashi, M., Sobirin, M. A., Ono, T., Hirabayashi, K., Yokota, T., Tanaka, S., Okita, K. & Tsutsui, H., Jan 1 2014, In : Endocrinology. 155, 1, p. 68-80 13 p.

Research output: Contribution to journalArticle

Diabetic Diet
Skeletal Muscle
Exercise
Diet
High Fat Diet