Research Output 1984 2019

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Review article
2019
3 Citations (Scopus)

Ivabradine for the treatment of cardiovascular diseases

Ide, T., Ohtani, K., Higo, T., Tanaka, M., Kawasaki, Y. & Tsutsui, H., Feb 1 2019, In : Circulation Journal. 83, 2, p. 252-260 9 p.

Research output: Contribution to journalReview article

ivabradine
Cardiovascular Diseases
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Sinoatrial Node
Heart Failure
2017
14 Citations (Scopus)

Nanoparticle-mediated drug delivery system for atherosclerotic cardiovascular disease

Matoba, T., Koga, J. I., Nakano, K., Egashira, K. & Tsutsui, H., Sep 1 2017, In : Journal of Cardiology. 70, 3, p. 206-211 6 p.

Research output: Contribution to journalReview article

Drug Delivery Systems
Nanoparticles
Cardiovascular Diseases
pioglitazone
Monocytes
66 Citations (Scopus)

The potential role and rationale for treatment of heart failure with sodium–glucose co-transporter 2 inhibitors

on behalf of the EMPEROR Trials Program, Nov 2017, In : European Journal of Heart Failure. 19, 11, p. 1390-1400 11 p.

Research output: Contribution to journalReview article

Symporters
Treatment Failure
Heart Failure
Type 2 Diabetes Mellitus
Medical Economics
2016
Natural Killer T-Cells
Galactosylceramides
Heart Failure
Myocardial Infarction
Ventricular Remodeling
2014
Molecular Pathology
Hypertrophic Cardiomyopathy
Dilated Cardiomyopathy
Diagnostic Imaging
Cardiomyopathies
18 Citations (Scopus)

Coronary flow reserve estimated by positron emission tomography to diagnose significant coronary artery disease and predict cardiac events

Naya, M., Tamaki, N. & Tsutsui, H., Dec 19 2014, In : Circulation Journal. 79, 1, p. 15-23 9 p.

Research output: Contribution to journalReview article

Positron-Emission Tomography
Coronary Artery Disease
Coronary Stenosis
Coronary Circulation
Microvessels
45 Citations (Scopus)

Physiological and pathological functions of NADPH oxidases during myocardial ischemia-reperfusion

Matsushima, S., Tsutsui, H. & Sadoshima, J., Jan 1 2014, In : Trends in Cardiovascular Medicine. 24, 5, p. 202-205 4 p.

Research output: Contribution to journalReview article

Myocardial Reperfusion
NADPH Oxidase
Myocardial Ischemia
Reactive Oxygen Species
Reperfusion Injury
2013
59 Citations (Scopus)

Exercise intolerance in chronic heart failure - Skeletal muscle dysfunction and potential therapies

Okita, K., Kinugawa, S. & Tsutsui, H., Feb 4 2013, In : Circulation Journal. 77, 2, p. 293-300 8 p.

Research output: Contribution to journalReview article

Skeletal Muscle
Heart Failure
Exercise
Exercise Tolerance
Anaerobiosis
2011
12 Citations (Scopus)

Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus

Tsutsui, H., Kinugawa, S., Matsushima, S. & Yokota, T., Jan 1 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 68-71 4 p.

Research output: Contribution to journalReview article

Oxidative stress
Medical problems
Muscle
Myocardium
Diabetes Mellitus
2010
33 Citations (Scopus)

Clinical characteristics and outcomes of heart failure with preserved ejection fraction: Lessons from epidemiological studies

Tsutsui, H., Tsuchihashi-Makaya, M. & Kinugawa, S., Jan 1 2010, In : Journal of Cardiology. 55, 1, p. 13-22 10 p.

Research output: Contribution to journalReview article

Epidemiologic Studies
Heart Failure
Stroke Volume
Atrial Fibrillation
Coronary Artery Disease
2009
231 Citations (Scopus)

Mitochondrial oxidative stress and dysfunction in myocardial remodelling

Tsutsui, H., Kinugawa, S. & Matsushima, S., Feb 1 2009, In : Cardiovascular research. 81, 3, p. 449-456 8 p.

Research output: Contribution to journalReview article

Mitochondrial DNA
Reactive Oxygen Species
Oxidative Stress
Peroxiredoxin III
DNA Damage
2007
5 Citations (Scopus)

Genetic polymorphisms and arrhythmia susceptibility

Makita, N. & Tsutsui, H., Jul 4 2007, In : Circulation Journal. 71, SUPPL. A

Research output: Contribution to journalReview article

Genetic Polymorphisms
Cardiac Arrhythmias
Heart Diseases
Cardiac Electrophysiology
Brugada Syndrome
2006
103 Citations (Scopus)

Mitochondrial oxidative stress, DNA damage, and heart failure

Tsutsui, H., Ide, T. & Kinugawa, S., Sep 1 2006, In : Antioxidants and Redox Signaling. 8, 9-10, p. 1737-1744 8 p.

Research output: Contribution to journalReview article

Oxidative stress
Mitochondrial DNA
DNA Damage
Reactive Oxygen Species
Oxidative Stress

Overview of therapeutic potential of rapamycin for coronary artery diseases in the era of the drug-eluting stent

Oyama, N., Sakai, H., Urasawa, K. & Tsutsui, H., Nov 1 2006, In : Vascular Disease Prevention. 3, 4, p. 285-289 5 p.

Research output: Contribution to journalReview article

Drug-Eluting Stents
Sirolimus
Coronary Artery Disease
Stents
Cyclin-Dependent Kinases
2005

Molecular mechanism in heart failure

Tsutsui, H., Feb 10 2005, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 94, 2, p. 190-194 5 p.

Research output: Contribution to journalReview article

Ribosomal Protein S6 Kinases
Myocardial Contraction
Angiotensin Type 1 Receptor
Ryanodine Receptor Calcium Release Channel
Ventricular Remodeling
2004
23 Citations (Scopus)

Novel pathophysiological insight and treatment strategies for heart failure - Lessons from mice and patients

Tsutsui, H., Dec 1 2004, In : Circulation Journal. 68, 12, p. 1095-1103 9 p.

Research output: Contribution to journalReview article

Heart Failure
Oxidative Stress
Therapeutics
DNA Damage
Reactive Oxygen Species
2003

Long-term prognosis of coronary artery bypass surgery in Japan

Tada, H., Tsutsui, H. & Takeshita, A., Jan 1 2003, In : Nippon rinsho. Japanese journal of clinical medicine. 61 Suppl 4, p. 583-587 5 p.

Research output: Contribution to journalReview article

Coronary Artery Bypass
Coronary Disease
Japan
1 Citation (Scopus)

PCI: results of nationwide survey in Japan

Tsutsui, H. & Takeshita, A., Jan 1 2003, In : Nippon rinsho. Japanese journal of clinical medicine. 61 Suppl 4, p. 489-494 6 p.

Research output: Contribution to journalReview article

Coronary Balloon Angioplasty
Coronary Disease
Registries
Japan
Outcome Assessment (Health Care)
2 Citations (Scopus)

Role of oxidative stress in heart failure

Tsutsui, H., Jan 1 2003, In : Nippon rinsho. Japanese journal of clinical medicine. 61, 5, p. 756-760 5 p.

Research output: Contribution to journalReview article

Reactive Oxygen Species
Oxidative Stress
Heart Failure
Electron Transport
Mitochondrial DNA
1999
1 Citation (Scopus)

Role of microtubules in the transition from compensated cardiac hypertrophy to failure

Tsutsui, H., Tagawa, H., Cooper IV, G. & Takeshita, A., Dec 1 1999, In : Heart Failure Reviews. 4, 4, p. 311-318 8 p.

Research output: Contribution to journalReview article

Cardiomegaly
Microtubules
Muscle Cells
Heart Failure
Blood Pressure
1994
113 Citations (Scopus)

Role of microtubules in contractile dysfunction of hypertrophied cardiocytes

Tsutsui, H., Tagawa, H., Kent, R. L., McCollam, P. L., Ishihara, K., Nagatsu, M. & Cooper IV, G., Jan 1 1994, In : Circulation. 90, 1, p. 533-555 23 p.

Research output: Contribution to journalReview article

Microtubules
Sarcomeres
Cardiomegaly
Cytoskeleton
Pressure