Department of Basic Medicine

Research Output 1980 2019

2019

A case of autonomous cortisol secretion in a patient with subclinical Cushing's syndrome, GNAS mutation, and paradoxical cortisol response to dexamethasone

Sakaguchi, C., Ashida, K., Kouhashi, K., Ohe, K., Fujii, Y., Yano, S., matsuda, Y., Sakamoto, S., Sakamoto, R., Oda, Y., Nomura, M. & Ogawa, Y., Jan 22 2019, In : BMC Endocrine Disorders. 19, 1, 13.

Research output: Contribution to journalArticle

Cushing Syndrome
Dexamethasone
Hydrocortisone
Mutation
Oral Administration

aCGH Analysis of Predictive Biomarkers for Response to Bevacizumab plus Oxaliplatin- or Irinotecan-Based Chemotherapy in Patients with Metastatic Colorectal Cancer

Fujita, Y., Taguri, M., Yamazaki, K., Tsurutani, J., Sakai, K., Tsushima, T., Nagase, M., Tamagawa, H., Ueda, S., Tamura, T., Tsuji, Y., Murata, K., Taira, K., Denda, T., Moriwaki, T., Funai, S., Nakajima, T. E., Muro, K., Tsuji, A., Yoshida, M. & 11 othersSuyama, K., Kurimoto, T., Sugimoto, N., Baba, E., Seki, N., Sato, M., Shimura, T., Boku, N., Hyodo, I., Yamanaka, T. & Nishio, K., Mar 1 2019, In : Oncologist. 24, 3, p. 327-337 11 p.

Research output: Contribution to journalArticle

irinotecan
oxaliplatin
Comparative Genomic Hybridization
Colorectal Neoplasms
Biomarkers

A Clinicopathological and Prognostic Analysis of PD-L2 Expression in Surgically Resected Primary Lung Squamous Cell Carcinoma

Matsubara, T., Takada, K., Azuma, K., Takamori, S., Toyokawa, G., Haro, A., Osoegawa, A., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Jun 15 2019, In : Annals of Surgical Oncology. 26, 6, p. 1925-1933 9 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Ligands
Lung
CD274 Antigen
Immunotherapy

A highly efficient method for concentrating DNA from river water by combined coagulation and foam separation

Suzuki, Y., Imafuku, Y., Nishiyama, M., Teranishi, K., Jikumaru, A., Nukazawa, K. & Ogura, Y., Jan 1 2019, (Accepted/In press) In : Separation Science and Technology (Philadelphia).

Research output: Contribution to journalArticle

Coagulation
Foams
DNA
Rivers
Water

A simple method for semi-automatic readjustment for positioning in post-mortem head computed tomography imaging

Kawazoe, Y., Morishita, J., Matsunobu, Y., Okumura, M., Shin, S., Usumoto, Y. & Ikeda, N., Mar 1 2019, In : Journal of Forensic Radiology and Imaging. 16, p. 57-64 8 p.

Research output: Contribution to journalArticle

Head
Tomography
Yaws

Budding Uninhibited by Benzimidazole-1 Insufficiency Prevents Acute Renal Failure in Severe Sepsis by Maintaining Anticoagulant Functions of Vascular Endothelial Cells

Matsubara, Y., Matsumoto, T., Yoshiya, K., Yoshida, A., Ikeda, S., Furuyama, T., Nakatsu, Y., Tsuzuki, T., Nomura, M. & Maehara, Y., Mar 1 2019, In : Shock (Augusta, Ga.). 51, 3, p. 364-371 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Anticoagulants
Sepsis
Endothelial Cells
Thrombomodulin

Clinical and computed tomography characteristics of non-small cell lung cancer with ALK gene rearrangement: Comparison with EGFR mutation and ALK/EGFR-negative lung cancer

Mori, M., Hayashi, H., Fukuda, M., Honda, S., Kitazaki, T., Shigematsu, K., Matsuyama, N., Otsubo, M., Nagayasu, T., Hashisako, M., Tabata, K., Uetani, M. & Ashizawa, K., Apr 1 2019, In : Thoracic Cancer. 10, 4, p. 872-879 8 p.

Research output: Contribution to journalArticle

Open Access
Gene Rearrangement
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Tomography
Mutation
1 Citation (Scopus)

Co-expression of IDO1 and PD-L1 in lung squamous cell carcinoma: Potential targets of novel combination therapy

Takada, K., Kouhashi, K., Shimokawa, M., Haro, A., Osoegawa, A., Tagawa, T., Seto, T., Oda, Y. & Maehara, Y., Feb 1 2019, In : Lung Cancer. 128, p. 26-32 7 p.

Research output: Contribution to journalArticle

CD274 Antigen
Indoleamine-Pyrrole 2,3,-Dioxygenase
Squamous Cell Carcinoma
Lung
Therapeutics
1 Citation (Scopus)

Cooperation between different variants: A unique potential for virus evolution

Shirogane, Y., Watanabe, S. & Yanagi, Y., Apr 15 2019, In : Virus Research. 264, p. 68-73 6 p.

Research output: Contribution to journalReview article

Genome
Viruses
Defective Viruses
Immune Evasion
RNA Replicase
Cuprizone
Phytoestrogens
Genistein
Demyelinating Diseases
Hippocampus

Diagnostic challenge of the newborn patients with heritable protein C deficiency

Ichiyama, M., Inoue, H., Ochiai, M., ishimura, M., Shiraishi, A., Fujiyoshi, J., Yamashita, H., Sato, K., Matsumoto, S., Hotta, T., Uchiumi, T., Kang, D. & Ohga, S., Feb 1 2019, In : Journal of Perinatology. 39, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

Protein C Deficiency
Protein C
Protein S
Newborn Infant
Mutation

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., Apr 15 2019, In : Experimental Cell Research. 377, 1-2, p. 24-35 12 p.

Research output: Contribution to journalArticle

Open Access
Microsatellite Instability
DNA Mismatch Repair
Mutation
Microsatellite Repeats
Hereditary Nonpolyposis Colorectal Neoplasms

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot

Yamamura, K., Sakamoto, I., Morihana, E., Hirata, Y., Nagata, H., Yamasaki, Y., Okumura, Y., Kouhashi, K., Koto, K., Tsutsui, H. & Ohga, S., Jul 15 2019, In : International Journal of Cardiology. 287, p. 121-126 6 p.

Research output: Contribution to journalArticle

Tetralogy of Fallot
Liver Cirrhosis
Carcinoma
Liver
Hyaluronic Acid
Type 1 Diabetes Mellitus
Hypoglycemia
Pancreatitis
C-Peptide
Pancreas
Gyrus Cinguli
Alzheimer Disease
Temporal Lobe
Brain
Frontal Lobe
Sex Hormone-Binding Globulin
Genetic Polymorphisms
Androgens
Prostatic Neoplasms
Testosterone

Glypican-3 expression in malignant small round cell tumors

Shibui, Y., Miyoshi, K., Kouhashi, K., Kinoshita, Y., Kuda, M., Yamamoto, H., Taguchi, T. & Oda, Y., Mar 1 2019, In : Oncology Letters. 17, 3, p. 3523-3528 6 p.

Research output: Contribution to journalArticle

Glypicans
Neoplasms
Neuroblastoma
Ewing's Sarcoma
Desmoplastic Small Round Cell Tumor
Neuroendocrine Tumors
Neuroblastoma
Pheochromocytoma
Neoplasms
Ewing's Sarcoma

Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., Feb 1 2019, In : Anticancer research. 39, 2, p. 671-677 7 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Exome
Open Access
Genetic Polymorphisms
Caffeine
Healthy Volunteers
Heart Rate
Blood Pressure

Intrahepatic cholangiocarcinoma after the Fontan procedure

Shibui, Y., Kouhashi, K., Sakamoto, I., Yamamura, K. & Oda, Y., Mar 1 2019, In : Human Pathology: Case Reports. 15, p. 15-19 5 p.

Research output: Contribution to journalArticle

Fontan Procedure
Cholangiocarcinoma
Liver Cirrhosis
Heart Failure
Liver

Lipase/Oxovanadium Co-Catalyzed Dynamic Kinetic Resolution of Propargyl Alcohols: Competition between Racemization and Rearrangement

Kawanishi, S., Oki, S., Kundu, D. & Akai, S., May 3 2019, In : Organic Letters. 21, 9, p. 2978-2982 5 p.

Research output: Contribution to journalArticle

Lipase
alcohols
Magic
Kinetics
Enantiomers

Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging

Takizawa, N., Ogura, Y., Fujita, Y., Noda, T., Shigematsu, H., Hayashi, T. & Kurokawa, K., May 1 2019, In : Virology. 531, p. 126-140 15 p.

Research output: Contribution to journalArticle

Ribonucleoproteins
Influenza A virus
Product Packaging
Orthomyxoviridae
Genome
Exercise
Population
Independent Living
Japan
Light

Meteorological effects on severe hemoptysis: A hospital-based observational study

Ogata, H., Matsumoto, K., Shinozaki, S., Hasegawa, M., Nakamura, S., Mizusaki, S., Takao, T., Nakatomi, K., Nakashima, N., Takahashi, K., Soeda, H., Hanada, K. & Koto, H., Jan 1 2019, In : Respiratory Investigation.

Research output: Contribution to journalArticle

Hemoptysis
Observational Studies
Humidity
Meteorological Concepts
Logistic Models

Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle

Maki, T., Kajioka, S., Itsumi, M., Kareman, E., Lee, K., shiota, M. & Eto, M., Apr 1 2019, In : LUTS: Lower Urinary Tract Symptoms. 11, 2, p. O209-O217

Research output: Contribution to journalArticle

Smooth Muscle
Swine
Carbachol
Escin
Adrenergic Receptors

Multi-step genomic dissection of a suspected intra-hospital helicobacter cinaedi outbreak

Gotoh, Y., Taniguchi, T., Yoshimura, D., Katsura, K., Saeki, Y., Hirabara, Y., Fukuda, M., Takajo, I., Tomida, J., Kawamura, Y., Ogura, Y., Itoh, T., Misawa, N., Okayama, A. & Hayashi, T., Jan 1 2019, In : Microbial Genomics. 5, 1, 000236.

Research output: Contribution to journalArticle

Helicobacter
Disease Outbreaks
Dissection
Genome
Bacteremia

Navigation surgery using indocyanine green fluorescent imaging for hepatoblastoma patients

Sozaki, R., Kawakubo, N., Matsuura, T., Yoshimaru, K., Koga, Y., Takemoto, J., Shibui, Y., Kouhashi, K., Hayashida, M., Oda, Y., Ohga, S. & Taguchi, T., May 1 2019, In : Pediatric surgery international. 35, 5, p. 551-557 7 p.

Research output: Contribution to journalArticle

Hepatoblastoma
Indocyanine Green
Neoplasms
Liver
Lung
1 Citation (Scopus)

New Insights into Measles Virus Brain Infections

Watanabe, S., Shirogane, Y., Sato, Y., Hashiguchi, T. & Yanagi, Y., Feb 1 2019, In : Trends in Microbiology. 27, 2, p. 164-175 12 p.

Research output: Contribution to journalReview article

Measles virus
Virus Diseases
Brain
Subacute Sclerosing Panencephalitis
Viral Fusion Proteins

Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

Takeuchi, K., Matsumoto, K., Furuta, M., Fukuyama, S., Takeshita, T., Ogata, H., Suma, S., Shibata, Y., Shimazaki, Y., Hata, J., Ninomiya, T., Nakanishi, Y., Inoue, H. & Yamashita, Y., May 1 2019, In : Journal of Dental Research. 98, 5, p. 534-540 7 p.

Research output: Contribution to journalArticle

Periodontitis
Chronic Obstructive Pulmonary Disease
Vital Capacity
Confidence Intervals
Smoking

Phenotypic characterization and virulence-related properties of Escherichia albertii strains isolated from children with diarrhea in Brazil

Lima, M. P., Yamamoto, D., Santos, A. C. D. M., Ooka, T., Hernandes, R. T., Vieira, M. A. M., Santos, F. F., Silva, R. M., Hayashi, T. & Gomes, T. A. T., Mar 1 2019, In : Pathogens and disease. 77, 2

Research output: Contribution to journalArticle

Open Access
Escherichia
Brazil
Virulence
Diarrhea
Virulence Factors
1 Citation (Scopus)

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, H., Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T. & Nakashima, K., Feb 6 2019, In : Neuron. 101, 3, p. 472-485.e7

Research output: Contribution to journalArticle

Microglia
Epigenomics
Neurons
Transcription Factors
Genes

Possibility of lung cancer risk in indium-exposed workers: An 11-year multicenter cohort study

Nakano, M., Omae, K., Tanaka, A. & Hirata, M., May 1 2019, In : Journal of Occupational Health. 61, 3, p. 251-256 6 p.

Research output: Contribution to journalArticle

Open Access
Indium
Multicenter Studies
Lung Neoplasms
Cohort Studies
Tomography

Prediction of liver fibrosis using CT under respiratory control: New attempt using deformation vectors obtained by non-rigid registration technique

Nishie, A., Akahori, S., Asayama, Y., Ishigami, K., ushijima, Y., Kakihara, D., Nakayama, T., Takayama, Y., Fujita, N., Morita, K., Ishimatsu, K., Takao, S., Yoshizumi, T., Kouhashi, K., Li, Y. & Honda, H., Mar 1 2019, In : Anticancer research. 39, 3, p. 1417-1424 8 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Fibrosis
Liver
ROC Curve
Area Under Curve

Predictive equation for post-mortem interval using spectrophotometric values of post-mortem lividity: A pilot study

Usumoto, Y., Kudo, K., Tsuji, A., Ihama, Y. & Ikeda, N., Apr 1 2019, In : Forensic Science International. 297, p. 47-55 9 p.

Research output: Contribution to journalArticle

Color
Skin Pigmentation
Skin
Femoral Vein
Cadaver

Predictive equation to estimate post-mortem interval using spectrophotometric blood-colour values

Usumoto, Y., Kudo, K., Tsuji, A., Ihama, Y. & Ikeda, N., Jan 1 2019, In : Medicine, Science and the Law. 59, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

Color
Values
Thigh
Cadaver
Autopsy

Predictors of recurrence and postoperative outcomes in patients with non-skull base meningiomas based on modern neurosurgical standards

Michiwaki, Y., Hata, N., Amano, T., Suzuki, S. O., Akagi, Y., Kuga, D., Onozuka, D., Momosaki, S., Nakamizo, A., Yoshimoto, K., Iwaki, T. & Iihara, K., Mar 1 2019, In : Interdisciplinary Neurosurgery: Advanced Techniques and Case Management. 15, p. 30-37 8 p.

Research output: Contribution to journalArticle

Meningioma
Recurrence
Survival
Neoplasms
Multivariate Analysis

Prevalence of adult epilepsy in a general Japanese population: The Hisayama study

Tanaka, A., Hata, J., Akamatsu, N., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Ohara, T., Mizuno, T., Tsuji, S., Kitazono, T. & Ninomiya, T., Mar 1 2019, In : Epilepsia Open. 4, 1, p. 182-186 5 p.

Research output: Contribution to journalArticle

Open Access
Epilepsy
Population
Cerebrovascular Disorders
Confidence Intervals
Tonic-Clonic Epilepsy

Prognostic Impact of Programmed Death-Ligand 2 Expression in Primary Lung Adenocarcinoma Patients

Takamori, S., Takada, K., Azuma, K., Jogo, T., Shimokawa, M., Toyokawa, G., Hirai, F., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Jan 1 2019, In : Annals of Surgical Oncology.

Research output: Contribution to journalArticle

Ligands
Adenocarcinoma of lung
Immunotherapy
Disease-Free Survival
Survival

Pulmonary interstitial emphysema is a risk factor for poor prognosis and a cause of air leaks

Tachibana, Y., Taniguchi, H., Kondoh, Y., Kataoka, K., Hamada, N., Hashiguchi, T., Ichikado, K., Kishaba, T., Sato, S., Udo, E., Hashisako, M. & Fukuoka, J., Jan 1 2019, In : Respiratory Investigation.

Research output: Contribution to journalArticle

Pulmonary Emphysema
Air
Interstitial Lung Diseases
Mediastinal Emphysema
Pneumothorax

Risk factors for failure of vitrectomy cell block technique in cytological diagnosis of vitreoretinal lymphoma

Ito, T., Takeda, A., Fujiwara, K., Hasegawa, E., nakao, S., Ohishi, Y., Oda, Y., Yoshikawa, H. & Sonoda, K., Jan 1 2019, In : Graefe's Archive for Clinical and Experimental Ophthalmology.

Research output: Contribution to journalArticle

Cytological Techniques
Vitrectomy
Lymphoma
Cataract
Lymphocytes

Risk of depressive disorders after tobacco smoking cessation:a retrospective cohort study in Fukuoka, Japan

Fujita, T., Babazono, A., Harano, Y. & Jiang, P., Mar 23 2019, In : BMJ open. 9, 3, p. e025124

Research output: Contribution to journalArticle

Tobacco Use Cessation
Smoking Cessation
Depressive Disorder
Japan
Cohort Studies

Safety and efficacy of PD-1 inhibitors in non–small cell lung cancer patients positive for antinuclear antibodies

Yoneshima, Y., Tanaka, K., Shiraishi, Y., Hata, K., Watanabe, H., Harada, T., Otsubo, K., Iwama, E., Inoue, H., Masuda, S., Nakanishi, Y. & Okamoto, I., Apr 1 2019, In : Lung Cancer. 130, p. 5-9 5 p.

Research output: Contribution to journalArticle

Antinuclear Antibodies
Non-Small Cell Lung Carcinoma
Safety
Autoimmune Diseases
Disease-Free Survival

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study

Ohara, T., Hata, J., Tanaka, M., Honda, T., Yamakage, H., Yoshida, D., Inoue, T., Hirakawa, Y., Kusakabe, T., Shibata, M., Teraoka, T., Kitazono, T., Kanba, S., Satoh-Asahara, N. & Ninomiya, T., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dementia
Biomarkers
Alzheimer Disease
Vascular Dementia

The association of tobacco use with prescription of muscle relaxants, benzodiazepines, and opioid analgesics for non-cancer pain

Takaki, H., Ieiri, I., Shibuta, H., Onozuka, D. & Hagihara, A., Jan 9 2019, In : American Journal on Addictions.

Research output: Contribution to journalArticle

Tobacco Use
Benzodiazepines
Opioid Analgesics
Prescriptions
Pain
Genetic Polymorphisms
Polymorphism
Androgens
Testosterone
Prostatic Neoplasms
Obstructive Sleep Apnea
Amyloid
Neuroimaging
Cognition
Tomography

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J-I., Apr 1 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
Open Access
Cross-Sectional Studies
Smoking
Population
Japan
Environmental Pollution

Update of the FANTOM web resource: Expansion to provide additional transcriptome atlases

Lizio, M., Abugessaisa, I., Noguchi, S., Kondo, A., Hasegawa, A., Hon, C. C., De Hoon, M., Severin, J., Oki, S., Hayashizaki, Y., Carninci, P., Kasukawa, T. & Kawaji, H., Jan 8 2019, In : Nucleic acids research. 47, D1, p. D752-D758

Research output: Contribution to journalArticle

Atlases
Transcriptome
Gene Expression
Long Noncoding RNA
RNA