Department of Medical Education

Research Output 1983 2020

46 Citations (Scopus)

Activation of STAT5 by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes

Yamaoka, K., Otsuka, T., Niiro, H., Arinobu, Y., Niho, Y., Hamasaki, N. & Izuhara, K., Jan 15 1998, In : Journal of Immunology. 160, 2, p. 838-845 8 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Lipopolysaccharides
Monocytes
Prostaglandin-Endoperoxide Synthases
Granulocytes
14 Citations (Scopus)

Activation of the flavoprotein domain of gp91phox upon interaction with N-terminal p67phox (1-210) and the Rac complex

Nisimoto, Y., Ogawa, H., Miyano, K. & Tamura, M., Jul 27 2004, In : Biochemistry. 43, 29, p. 9567-9575 9 p.

Research output: Contribution to journalArticle

Flavoproteins
Chemical activation
Flavin-Adenine Dinucleotide
rac GTP-Binding Proteins
Fusion reactions
113 Citations (Scopus)

Activator or inhibitor? GSK-3 as a new drug target

Takahashi-Yanaga, F., Jan 1 2013, In : Biochemical Pharmacology. 86, 2, p. 191-199 9 p.

Research output: Contribution to journalComment/debate

Glycogen Synthase Kinase 3
Pharmaceutical Preparations
Protein-Serine-Threonine Kinases
Phosphotransferases
Osteitis
31 Citations (Scopus)

Activator protein-1 mediates shear stress-induced prostaglandin D synthase gene expression in vascular endothelial cells

Miyagi, M., Miwa, Y., Takahashi-Yanaga, F., Morimoto, S. & Sasaguri, T., May 1 2005, In : Arteriosclerosis, thrombosis, and vascular biology. 25, 5, p. 970-975 6 p.

Research output: Contribution to journalArticle

prostaglandin R2 D-isomerase
Lipocalins
Transcription Factor AP-1
Endothelial Cells
Gene Expression
30 Citations (Scopus)

Active and passive smoking and risk of Parkinson's disease

Tanaka, K., Miyake, Y., Fukushima, W., Sasaki, S., Kiyohara, C., Tsuboi, Y., Yamada, T., Oeda, T., Miki, T., Kawamura, N., Sakae, N., Fukuyama, H., Hirota, Y. & Nagai, M., Dec 1 2010, In : Acta Neurologica Scandinavica. 122, 6, p. 377-382 6 p.

Research output: Contribution to journalArticle

Tobacco Smoke Pollution
Parkinson Disease
Confidence Intervals
Odds Ratio
Social Adjustment
30 Citations (Scopus)

Acute blood pressure levels and neurological deterioration in different subtypes of ischemic stroke

Toyoda, K., Fujimoto, S., Kamouchi, M., Iida, M. & Okada, Y., Jul 1 2009, In : Stroke. 40, 7, p. 2585-2588 4 p.

Research output: Contribution to journalArticle

Stroke
Blood Pressure
National Institutes of Health (U.S.)
Blood Glucose
Hospitalization
11 Citations (Scopus)

Acute kidney injury and edaravone in acute ischemic stroke: The fukuoka stroke registry

Kamouchi, M., Sakai, H., Kiyohara, Y., Minematsu, K., Hayashi, K. & Kitazono, T., Nov 1 2013, In : Journal of Stroke and Cerebrovascular Diseases. 22, 8, p. e470-e476

Research output: Contribution to journalArticle

Acute Kidney Injury
Registries
Stroke
Propensity Score
Case-Control Studies
15 Citations (Scopus)

ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children

Matsusue, A., Kiyohara, C., Tanaka, K., Sasaki, S. & Miyake, Y., Apr 1 2009, In : Clinical Biochemistry. 42, 6, p. 477-483 7 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Atopic Dermatitis
Polymorphism
Haplotypes
Single Nucleotide Polymorphism
11 Citations (Scopus)

Adenovirus-mediated gene transfer to ischemic brain is augmented in aged rats

Takada, J., Ooboshi, H., Yao, H., Kitazono, T., Ibayashi, S. & Iida, M., Apr 1 2003, In : Experimental Gerontology. 38, 4, p. 423-429 7 p.

Research output: Contribution to journalArticle

Gene transfer
Adenoviridae
Rats
Brain
Genes
22 Citations (Scopus)

Adenovirus-mediated gene transfer to ischemic brain ischemic flow threshold for transgene expression

Ooboshi, H., Ibayashi, S., Takada, J., Yao, H., Kitazono, T. & Fujishima, M., Jan 1 2001, In : Stroke. 32, 4, p. 1043-1047 5 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Transgenes
Adenoviridae
Ischemia
Brain Ischemia
12 Citations (Scopus)

Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols

Shiwa, Y., Hachiya, T., Furukawa, R., Ohmomo, H., Ono, K., Kudo, H., Hata, J., Hozawa, A., Iwasaki, M., Matsuda, K., Minegishi, N., Satoh, M., Tanno, K., Yamaji, T., Wakai, K., Hitomi, J., Kiyohara, Y., Kubo, M., Tanaka, H., Tsugane, S. & 3 others, Yamamoto, M., Sobue, K. & Shimizu, A., Jan 1 2016, In : PloS one. 11, 1, e0147519.

Research output: Contribution to journalArticle

DNA methylation
DNA Methylation
Blood
DNA
blood
44 Citations (Scopus)

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: Immunological analysis of B cells, T cells and cytokines

Tamimoto, Y., Horiuchi, T., Tsukamoto, H., Otsuka, J., Mitoma, H., Kimoto, Y., Nakashima, H., Muta, K., Abe, Y., Kiyohara, C., Ueda, A., Nagasawa, K., Yoshizawa, S., Shimoda, T. & Harada, M., Jun 1 2008, In : Rheumatology. 47, 6, p. 821-827 7 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
B-Lymphocytes
Cytokines
T-Lymphocytes
Therapeutics
128 Citations (Scopus)

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: Individual participant meta-analysis

Wormser, D., Di Angelantonio, E., Kaptoge, S., Wood, A. M., Gao, P., Sun, Q., Walldius, G., Selmer, R., Monique Verschuren, W. M., Bueno-de-Mesquita, H. B., Engström, G., Ridker, P. M., Njølstad, I., Iso, H., Holme, I., Giampaoli, S., Tunstall-Pedoe, H., Gaziano, J. M., Brunner, E., Kee, F. & 246 others, Tosetto, A., Meisinger, C., Brenner, H., Ducimetiere, P., Whincup, P. H., Tipping, R. W., Ford, I., Cremer, P., Hofman, A., Wilhelmsen, L., Clarke, R., de Boer, I. H., Jukema, J. W., Ibañez, A. M., Lawlor, D. A., D'Agostino, R. B., Rodriguez, B., Casiglia, E., Stehouwer, C. D. A., Simons, L. A., Nietert, P. J., Barrett-Connor, E., Panagiotakos, D. B., Björkelund, C., Strandberg, T. E., Wassertheil-Smoller, S., Blazer, D. G., Meade, T. W., Welin, L., Svärdsudd, K., Woodward, M., Nissinen, A., Kromhout, D., Jørgensen, T., Tilvis, R. S., Guralnik, J. M., Rosengren, A., Taylor, J. O., Kiechl, S., Dagenais, G. R., Fowkes, F. G. R., Wallace, R. B., Khaw, K. T., Shaffer, J. A., Visser, M., Kauhanen, J., Salonen, J. T., Gallacher, J., Ben-Shlomo, Y., Kitamura, A., Sundström, J., Wennberg, P., Kiyohara, Y., Daimon, M., de la Cámara, A. G., Cooper, J. A., Onat, A., Devereux, R., Mukamal, K. J., Dankner, R., Knuiman, M. W., Crespo, C. J., Gansevoort, R. T., Goldbourt, U., Nordestgaard, B. G., Shaw, J. E., Mussolino, M., Nakagawa, H., Fletcher, A., Kuller, L. H., Gillum, R. F., Gudnason, V., Assmann, G., Wald, N., Jousilahti, P. R., Greenland, P., Trevisan, M., Ulmer, H., Butterworth, A. S., Folsom, A. R., Davey-Smith, G., Hu, F. B., Danesh, J., Simpson, L. M., Jungner, I., Demerath, E. W., Franceschini, N., Lutsey, P. L., Pitsavos, C., Chrysohoou, C., Stefanadis, C., Atkins, R., Zimmet, P. Z., Barr, E. L. M., Wannamethee, S. G., Morris, R. W., Willeit, J., Weger, S., Oberhollenzer, F., Ebrahim, S., Yarnell, J. W. G., Tikhonoff, V., Shay, C. M., Garside, D. B., Sutherland, S. E., Bachman, D. L., Keil, J. E., Kizer, J. R., Psaty, B. M., Tybjærg-Hansen, A., Jensen, G. B., Schnohr, P., Palmieri, L., Panico, S., Pilotto, L., Vanuzzo, D., Simons, J., McCallum, J., Friedlander, Y., Phillips, C. L., Kohout, F. J., Cornoni-Huntley, J. C., Wareham, N. J., Schöttker, B., Müller, H., Rothenbacher, D., Jansson, J. H., Donfrancesco, C., Vartiainen, E., Harald, K., Salomaa, V., Vasan, R. S., Fox, C. S., Pencina, M. J., Oizumi, T., Kayama, T., Kato, T., Bladbjerg, E. M., Møller, L., Jespersen, J., Chetrit, A., Lubin, F., Eriksson, H., Lappas, G., Bengtsson, C., Lissner, L., Nagel, D., Miettinen, T. A., Arima, H., Doi, Y., Ninomiya, T., Dekker, J. M., Nijpels, G., Rimm, E. B., Willett, W. C., Yamagishi, K., Noda, H., Kurl, S., Tuomainen, T. P., Poppelaars, J. L., Deeg, D. J. H., De Stavola, B. L., Hedblad, B., Nilsson, P., Blokstra, A., Shea, S. J., Thorand, B., Koenig, W., Döring, A., Nitsch, D., Grandits, G., Tverdal, A., Nystad, W., Manson, J. E., Hankinson, S. E., Bauer, K. A., Davidson, K. W., Kirkland, S., Shimbo, D., Sato, S., Miura, K., Sakurai, M., Jouven, X., Bakker, S. J. L., van der Harst, P., Hillege, H. L., Garcia-Palmieri, M. R., Amouyel, P., Arveiler, D., Ferrières, J., Schulte, H., de Craen, A. J. M., Sattar, N., Stott, D. J., Cantin, B., Lamarche, B., Després, J. P., Bergstrom, J., Bettencourt, R. R., Buisson, C., Aspelund, T., Sigurdsson, G., Thorsson, B., Ikram, M. A., Tiemeier, H., Witteman, J. C. M., Tavendale, R., Lowe, G. D. O., Yeh, J. L., Ali, T., Calhoun, D., Can, G., Nakamura, K., Morikawa, Y., Mathiesen, E. B., Løchen, M. L., Wilsgaard, T., Ingelsson, E., Michaëlsson, K., Cederholm, T., Buring, J., Diem, G., Concin, H., Rodeghiero, F., Marmot, M., Kivimaki, M. S. M., Robertson, M., Feskens, E., Geleijnse, J. M., Kromhout, D., Walker, M., Watson, S., Alexander, M., Franco, O. H., Gobin, R., Haycock, P., Kaptoge, S., Seshasai, S. R. K., Lewington, S., Pennells, L., Rapsomaniki, E., Sarwar, N., Thompson, A., Thompson, S. G., White, I. R. & Zhao, X., Oct 1 2012, In : International Journal of Epidemiology. 41, 5, p. 1419-1433 15 p.

Research output: Contribution to journalArticle

Blood Vessels
Meta-Analysis
Cause of Death
Morbidity
Chronic Obstructive Pulmonary Disease
4 Citations (Scopus)
Dementia
Registries
Stroke
Propensity Score
Logistic Models
5 Citations (Scopus)

A first report of East Asian students' perception of progress testing: a focus group study

Matsuyama, Y., Muijtjens, A. M. M., Kikukawa, M., Stalmeijer, R., Murakami, R., Ishikawa, S. & Okazaki, H., Sep 22 2016, In : BMC Medical Education. 16, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

study group
student
learning
teacher
school
13 Citations (Scopus)

A framework for quantifying net benefits of alternative prognostic models

Rapsomaniki, E., White, I. R., Wood, A. M., Thompson, S. G., Tipping, R. W., Ford, C. E., Simpson, L. M., Folsom, A. R., Chambless, L. E., Panagiotakos, D. B., Pitsavos, C., Chrysohoou, C., Stefanadis, C., Knuiman, M., Whincup, P. H., Wannamethee, S. G., Morris, R. W., Kiechl, S., Willeit, J., Oberhollenzer, F. & 166 others, Mayr, A., Wald, N., Lawlor, D. A., Yarnell, J. W., Gallacher, J., Casiglia, E., Tikhonoff, V., Nietert, P. J., Sutherland, S. E., Bachman, D. L., Keil, J. E., Cushman, M., Tracy, R., Tybjærg-Hansen, A., Nordestgaard, B. G., Frikke-Schmidt, R., Giampaoli, S., Palmieri, L., Panico, S., Vanuzzo, D., Pilotto, L., Gómez de la Cámara, A., Gómez Gerique, J. A., Simons, L., McCallum, J., Friedlander, Y., Lee, A. J., Taylor, J., Guralnik, J. M., Wallace, R., Guralnik, J. M., Blazer, D. G., Guralnik, J. M., Guralnik, J. M., Khaw, K. T., Schöttker, B., Müller, H., Rothenbacher, D., Jansson, J. H., Wennberg, P., Nissinen, A., Donfrancesco, C., Salomaa, V., Harald, K., Jousilahti, P., Vartiainen, E., Woodward, M., D'Agostino, R. B., Wolf, P. A., Vasan, R. S., Pencina, M. J., Bladbjerg, E. M., Jørgensen, T., Møller, L., Jespersen, J., Dankner, R., Chetrit, A., Lubin, F., Rosengren, A., Lappas, G., Eriksson, H., Björkelund, C., Lissner, L., Bengtsson, C., Nagel, D., Kiyohara, Y., Arima, H., Doi, Y., Ninomiya, T., Rodriguez, B., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Iso, H., Kitamura, A., Yamagishi, K., Noda, H., Goldbourt, U., Kauhanen, J., Salonen, J. T., Cooper, J. A., Verschuren, W. M. M., Blokstra, A., Cushman, M., Folsom, A. R., Shea, S., Döring, A., Meisinger, C., Verschuren, W. M. M., Blokstra, A., Bueno-de-Mesquita, H. B., Rosengren, A., Lappas, G., Kuller, L. H., Grandits, G., Gillum, R. F., Mussolino, M., Cooper, J. A., Bauer, K. A., Kirkland, S., Shaffer, J., Korin, M. R., Kitamura, A., Iso, H., Sato, S., Amouyel, P., Arveiler, D., Evans, A., Ferrières, J., Schulte, H., Assmann, G., Westendorp, R. G., Buckley, B. M., Packard, C. J., Sattar, N., Cantin, B., Després, J. P., Dagenais, G. R., Barrett-Connor, E., Wingard, D. L., Bettencourt, R., Gudnason, V., Aspelund, T., Sigurdsson, G., Thorsson, B., Witteman, J., Kardys, I., Tiemeier, H., Hofman, A., Tunstall-Pedoe, H., Tavendale, R., Lowe, G. D. O., Woodward, M., Howard, B. V., Zhang, Y., Best, L., Umans, J., Ben-Shlomo, Y., Davey-Smith, G., Njølstad, I., Wilsgaard, T., Ingelsson, E., Lind, L., Giedraitis, V., Lannfelt, L., Gaziano, J. M., Stampfer, M., Ridker, P., Gaziano, J. M., Ridker, P., Wassertheil-Smoller, S., Manson, J. E., Marmot, M., Clarke, R., Fletcher, A., Brunner, E., Shipley, M., Ridker, P., Buring, J., Shepherd, J., Cobbe, S. M., Ford, I., Robertson, M., Marín Ibañez, A., Feskens, E. J. M. & Kromhout, D., Jan 30 2012, In : Statistics in Medicine. 31, 2, p. 114-130 17 p.

Research output: Contribution to journalArticle

Health
Alternatives
Economics
Cost-Benefit Analysis
Cardiovascular Diseases
38 Citations (Scopus)

A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis

Horiuchi, T., Kiyohara, C., Tsukamoto, H., Sawabe, T., Furugo, I., Yoshizawa, S., Ueda, A., Tada, Y., Nakamura, T., Kimoto, Y., Mitoma, H., Harashima, S., Yoshizawa, S., Shimoda, T., Okamura, S., Nagasawa, K. & Harada, M., Mar 1 2007, In : Annals of the Rheumatic Diseases. 66, 3, p. 320-324 5 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type II
Polymorphism
Systemic Lupus Erythematosus
Meta-Analysis
Case-Control Studies
36 Citations (Scopus)

A fusion protein between rac and p67phox (1 - 210) reconstitutes NADPH oxidase with higher activity and stability than the individual components

Miyano, K., Ogasawara, S., Han, C. H., Fukuda, H. & Tamura, M., Nov 20 2001, In : Biochemistry. 40, 46, p. 14089-14097 9 p.

Research output: Contribution to journalArticle

rac GTP-Binding Proteins
NADPH Oxidase
Fusion reactions
Chemical activation
Proteins
8 Citations (Scopus)

A genome-wide association study of late-onset Alzheimer's disease in a Japanese population

Hirano, A., Ohara, T., Takahashi, A., Aoki, M., Fuyuno, Y., Ashikawa, K., Morihara, T., Takeda, M., Kamino, K., Oshima, E., Okahisa, Y., Shibata, N., Arai, H., Akatsu, H., Ikeda, M., Iwata, N., Ninomiya, T., Monji, A., Kitazono, T., Kiyohara, Y. & 2 others, Kubo, M. & Kanba, S., Aug 1 2015, In : Psychiatric Genetics. 25, 4, p. 139-146 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer Disease
Population
Introns
12 Citations (Scopus)

Age-related changes in response of brain stem vessels to opening of ATP-sensitive potassium channels

Toyoda, K., Fujii, K., Takata, Y., Ibayashi, S., Kitazono, T., Nagao, T., Fujikawa, M. & Fujishima, M., Jan 1997, In : Stroke. 28, 1, p. 171-175 5 p.

Research output: Contribution to journalArticle

KATP Channels
Brain Stem
Adenosine Triphosphate
Vasodilator Agents
Basilar Artery
10 Citations (Scopus)

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN)

the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Jan 1 2017, In : Journal of epidemiology. 27, 3, p. 123-129 7 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Japan
Cardiovascular Diseases
Mortality
Research

A greater reduction in the distal femoral anterior condyle improves flexion after total knee arthroplasty in patients with osteoarthritis

Nishitani, K., Hatada, R., Kuriyama, S., Lyman, S. L., Nakamura, S., Ito, H. & Matsuda, S., Dec 2019, In : Knee. 26, 6, p. 1364-1371 8 p.

Research output: Contribution to journalArticle

Knee Replacement Arthroplasties
Thigh
Osteoarthritis
Knee
Bone and Bones
33 Citations (Scopus)

A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter

Umeno, J., Hisamatsu, T., Esaki, M., Hirano, A., Kubokura, N., Asano, K., Kochi, S., Yanai, S., Fuyuno, Y., Shimamura, K., Hosoe, N., Ogata, H., Watanabe, T., Aoyagi, K., Ooi, H., Watanabe, K., Yasukawa, S., Hirai, F., Matsui, T., Iida, M. & 6 others, Yao, T., Hibi, T., Kosaki, K., Kanai, T., Kitazono, T. & Matsumoto, T., Nov 2015, In : PLoS genetics. 11, 11, e1005581.

Research output: Contribution to journalArticle

digestive system diseases
prostaglandins
Prostaglandins
transporters
mutation
6 Citations (Scopus)

A J-shaped association between serum uric acid levels and poor renal survival in female patients with IgA nephropathy

Matsukuma, Y., Masutani, K., Tanaka, S., Tsuchimoto, A., Fujisaki, K., Torisu, K., Katafuchi, R., Hirakata, H., Tsuruya, K. & Kitazono, T., Mar 1 2017, In : Hypertension Research. 40, 3, p. 291-297 7 p.

Research output: Contribution to journalArticle

Uric Acid
Immunoglobulin A
Kidney
IGA Glomerulonephritis
Chronic Kidney Failure
26 Citations (Scopus)

Albuminuria and chronic kidney disease in association with the metabolic syndrome.

Ninomiya, T. & Kiyohara, Y., Jan 1 2007, In : Journal of the cardiometabolic syndrome. 2, 2, p. 104-107 4 p.

Research output: Contribution to journalReview article

Albuminuria
Chronic Renal Insufficiency
Kidney
Cardiovascular Diseases
Premature Mortality
528 Citations (Scopus)

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes

Ninomiya, T., Perkovic, V., De Galan, B. E., Zoungas, S., Pillai, A., Jardine, M., Patel, A., Cass, A., Neal, B., Poulter, N., Mogensen, C. E., Cooper, M., Marre, M., Williams, B., Hamet, P., Mancia, G., Woodward, M., MacMahon, S. & Chalmers, J., Aug 1 2009, In : Journal of the American Society of Nephrology. 20, 8, p. 1813-1821 9 p.

Research output: Contribution to journalArticle

Albuminuria
Albumins
Creatinine
Kidney
Type 2 Diabetes Mellitus
11 Citations (Scopus)

Albuminuria as a risk factor for peripheral arterial disease in a general population - The Hisayama Study

Usui, T., Ninomiya, T., Nagata, M., Doi, Y., Hata, J., Fukuhara, M. & Kiyohara, Y., Aug 31 2011, In : Journal of atherosclerosis and thrombosis. 18, 8, p. 705-712 8 p.

Research output: Contribution to journalArticle

Albuminuria
Peripheral Arterial Disease
Albumins
Creatinine
Population
4 Citations (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
3 Citations (Scopus)

Alcohol consumption and lung cancer risk among Japanese: a meta-analysis.

Uehara, Y. & Kiyohara, C., May 1 2010, In : Fukuoka igaku zasshi = Hukuoka acta medica. 101, 5, p. 101-108 8 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Meta-Analysis
Lung Neoplasms
Epidemiologic Studies
Smoking
13 Citations (Scopus)

Alcohol drinking and risk of Parkinson's disease: A case-control study in Japan

Fukushima, W., Miyake, Y., Tanaka, K., Sasaki, S., Kiyohara, C., Tsuboi, Y., Yamada, T., Oeda, T., Miki, T., Kawamura, N., Sakae, N., Fukuyama, H., Hirota, Y. & Nagai, M., Nov 5 2010, In : BMC neurology. 10, 111.

Research output: Contribution to journalArticle

Alcohol Drinking
Parkinson Disease
Case-Control Studies
Japan
Alcohols
17 Citations (Scopus)

Aldosterone-and-salt-induced cardiac fibrosis is independent from angiotensin II type 1a receptor signaling in mice

Kagiyama, S., Matsumura, K., Fukuhara, M., Sakagami, K., Fujii, K. & Iida, M., Oct 1 2007, In : Hypertension Research. 30, 10, p. 979-989 11 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Aldosterone
Fibrosis
Salts
Connective Tissue Growth Factor
40 Citations (Scopus)

Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: The Hisayama study

Shibata, M., Ninomiya, T., Jensen, M. P., Anno, K., Yonemoto, K., Makino, S., Iwaki, R., Yamashiro, K., Yoshida, T., Imada, Y., Kubo, C., Kiyohara, Y., Sudo, N. & Hosoi, M., Mar 12 2014, In : PloS one. 9, 3, e90984.

Research output: Contribution to journalArticle

Affective Symptoms
Chronic Pain
pain
Population
Medical problems
25 Citations (Scopus)

A low ankle brachial index is associated with an increased risk of cardiovascular disease: The hisayama study

Kojima, I., Ninomiya, T., Hata, J., Fukuhara, M., Hirakawa, Y., Mukai, N., Yoshida, D., Kitazono, T. & Kiyohara, Y., Jan 1 2014, In : Journal of atherosclerosis and thrombosis. 21, 9, p. 966-973 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Cardiovascular Diseases
Confidence Intervals
Blood Pressure
Independent Living
28 Citations (Scopus)

Altered cerebrovascular response to a potassium channel opener in hypertensive rats

Takaba, H., Nagao, T., Ibayashi, S., Kitazono, T., Fujii, K. & Fujishima, M., Jul 1996, In : Hypertension. 28, 1, p. 143-146 4 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Potassium Channels
KATP Channels
Inbred WKY Rats
Cilazapril
116 Citations (Scopus)

Altered expression of diabetes-related genes in Alzheimer's disease brains: The Hisayama study

Hokama, M., Oka, S., Leon, J., Ninomiya, T., Honda, H., Sasaki, K., Iwaki, T., Ohara, T., Sasaki, T., LaFerla, F. M., Kiyohara, Y. & Nakabeppu, Y., Sep 2014, In : Cerebral Cortex. 24, 9, p. 2476-2488 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Brain
Genes
Diabetes Mellitus
Brain Diseases
4 Citations (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
4 Citations (Scopus)

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

Tsuchihashi, T., Tsukashima, A., Matsumura, K., Abe, I., Tominaga, M., Nakao, Y., Kobayashi, K. & Fujishima, M., Sep 1 1991, In : European Journal of Clinical Pharmacology. 41, 3, p. 255-257 3 p.

Research output: Contribution to journalArticle

nilvadipine
Ambulatory Blood Pressure Monitoring
Calcium
Blood Pressure
Heart Rate

A medical record peer-review system to evaluate residents’ clinical competence: Criterion validity analysis

Kameoka, J., Kikukawa, M., Kobayashi, D., Okubo, T., Ishii, S. & Kagaya, Y., Aug 2019, In : Tohoku Journal of Experimental Medicine. 248, 4, p. 253-260 8 p.

Research output: Contribution to journalArticle

Open Access
Peer Review
Clinical Competence
Medical Records
Medical education
Supervisory personnel
48 Citations (Scopus)

Amelioration of autoimmune nephritis by imatinib in MRL/lpr mice

Sadanaga, A., Nakashima, H., Masutani, K., Miyake, K., Shimizu, S., Igawa, T., Sugiyama, N., Niiro, H., Hirakata, H. & Harada, M., Dec 1 2005, In : Arthritis and rheumatism. 52, 12, p. 3987-3996 10 p.

Research output: Contribution to journalArticle

Inbred MRL lpr Mouse
Nephritis
Glomerulonephritis
Platelet-Derived Growth Factor Receptors
Lupus Nephritis
48 Citations (Scopus)

A meta-analysis of the evidence on the impact of prenatal and early infancy exposures to mercury on autism and attention deficit/hyperactivity disorder in the childhood

Yoshimasu, K., Kiyohara, C., Takemura, S. & Nakai, K., Sep 2014, In : NeuroToxicology. 44, p. 121-131 11 p.

Research output: Contribution to journalReview article

Thimerosal
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Mercury
Meta-Analysis
13 Citations (Scopus)

Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes

Nakamura, K., Kamouchi, M., Kitazono, T., Kuroda, J., Shono, Y., Hagiwara, N., Ago, T., Ooboshi, H., Ibayashi, S. & Iida, M., May 1 2009, In : Microvascular Research. 77, 3, p. 327-334 8 p.

Research output: Contribution to journalArticle

Pericytes
Amiloride
Hydrogen Peroxide
Sodium-Hydrogen Antiporter
Acid Sensing Ion Channels
9 Citations (Scopus)

A model teaching session for the hypothesis-driven physical examination

Nishigori, H., Masuda, K., Kikukawa, M., Kawashima, A., Yudkowsky, R., Bordage, G. & Otaki, J., May 1 2011, In : Medical Teacher. 33, 5, p. 410-417 8 p.

Research output: Contribution to journalArticle

Physical Examination
Teaching
examination
Students
diagnostic
18 Citations (Scopus)

Amplification of IL-21 signalling pathway through bruton's tyrosine kinase in human B cell activation

Wang, S. P., Iwata, S., Nakayamada, S., Niiro, H., Jabbarzadeh-Tabrizi, S., Kondo, M., Kubo, S., Yoshikawa, M. & Tanaka, Y., May 5 2015, In : Rheumatology (United Kingdom). 54, 8, p. 1488-1497 10 p., keu532.

Research output: Contribution to journalArticle

B-Lymphocytes
Phosphorylation
interleukin-21
Agammaglobulinaemia tyrosine kinase
Genetic Recombination
21 Citations (Scopus)

Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation

Iwata, S., Yamaoka, K., Niiro, H., Nakano, K., Wang, S. P., Akashi, K. & Tanaka, Y., Jun 2012, In : Journal of Allergy and Clinical Immunology. 129, 6, p. 1594-1601.e2

Research output: Contribution to journalArticle

Toll-Like Receptors
B-Lymphocytes
TNF Receptor-Associated Factor 6
B-Lymphocyte Subsets
human SYK protein
7 Citations (Scopus)

A multicenter, prospective, observational study of warfarin-associated intracerebral hemorrhage: The SAMURAI-WAICH study

Osaki, M., Koga, M., Maeda, K., Hasegawa, Y., Nakagawara, J., Furui, E., Todo, K., Kimura, K., Shiokawa, Y., Okada, Y., Okuda, S., Kario, K., Yamagami, H., Minematsu, K., Kitazono, T. & Toyoda, K., Dec 15 2015, In : Journal of the Neurological Sciences. 359, 1-2, p. 72-77 6 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Warfarin
Observational Studies
Prospective Studies
Anticoagulants
6 Citations (Scopus)

An advanced case of indium lung disease with progressive emphysema

Nakano, M., Tanaka, A., Hirata, M., Kumazoe, H., Wakamatsu, K., Kamada, D. & Omae, K., Jan 1 2016, In : Journal of Occupational Health. 58, 5, p. 477-481 5 p.

Research output: Contribution to journalArticle

Indium
Emphysema
Lung Diseases
Respiratory Function Tests
Vital Capacity
34 Citations (Scopus)

Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells

Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., May 1 2011, In : Rheumatology. 50, 5, p. 944-952 9 p., keq414.

Research output: Contribution to journalArticle

Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Stem Cells
Sclerosis
2 Citations (Scopus)

Analysis of Japanese articles about suicides involving charcoal burning or hydrogen sulfide gas

Nabeshima, Y., Onozuka, D., Kitazono, T. & Hagihara, A., Oct 2016, In : International journal of environmental research and public health. 13, 10, 1013.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Charcoal
Suicide
Gases
Newspapers
7 Citations (Scopus)
Ambulances
Particulate Matter
Japan
Emergencies
Cardiovascular Diseases
29 Citations (Scopus)

An ATP-sensitive potassium channel activator reduces infarct volume in focal cerebral ischemia in rats

Takaba, H., Nagao, T., Yao, H., Kitazono, T., Ibayashi, S. & Fujishima, M., Oct 18 1997, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 273, 2 42-2, p. R583-R586

Research output: Contribution to journalArticle

Cerebrovascular Circulation
KATP Channels
Brain Ischemia
Control Groups
Laser-Doppler Flowmetry