Department of Medical Education

Research Output 1983 2020

Article
15 Citations (Scopus)

ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children

Matsusue, A., Kiyohara, C., Tanaka, K., Sasaki, S. & Miyake, Y., Apr 1 2009, In : Clinical Biochemistry. 42, 6, p. 477-483 7 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Atopic Dermatitis
Polymorphism
Haplotypes
Single Nucleotide Polymorphism
11 Citations (Scopus)

Adenovirus-mediated gene transfer to ischemic brain is augmented in aged rats

Takada, J., Ooboshi, H., Yao, H., Kitazono, T., Ibayashi, S. & Iida, M., Apr 1 2003, In : Experimental Gerontology. 38, 4, p. 423-429 7 p.

Research output: Contribution to journalArticle

Gene transfer
Adenoviridae
Rats
Brain
Genes
22 Citations (Scopus)

Adenovirus-mediated gene transfer to ischemic brain ischemic flow threshold for transgene expression

Ooboshi, H., Ibayashi, S., Takada, J., Yao, H., Kitazono, T. & Fujishima, M., Jan 1 2001, In : Stroke. 32, 4, p. 1043-1047 5 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Transgenes
Adenoviridae
Ischemia
Brain Ischemia
13 Citations (Scopus)

Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols

Shiwa, Y., Hachiya, T., Furukawa, R., Ohmomo, H., Ono, K., Kudo, H., Hata, J., Hozawa, A., Iwasaki, M., Matsuda, K., Minegishi, N., Satoh, M., Tanno, K., Yamaji, T., Wakai, K., Hitomi, J., Kiyohara, Y., Kubo, M., Tanaka, H., Tsugane, S. & 3 others, Yamamoto, M., Sobue, K. & Shimizu, A., Jan 1 2016, In : PloS one. 11, 1, e0147519.

Research output: Contribution to journalArticle

DNA methylation
DNA Methylation
Blood
DNA
blood
44 Citations (Scopus)

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: Immunological analysis of B cells, T cells and cytokines

Tamimoto, Y., Horiuchi, T., Tsukamoto, H., Otsuka, J., Mitoma, H., Kimoto, Y., Nakashima, H., Muta, K., Abe, Y., Kiyohara, C., Ueda, A., Nagasawa, K., Yoshizawa, S., Shimoda, T. & Harada, M., Jun 1 2008, In : Rheumatology. 47, 6, p. 821-827 7 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
B-Lymphocytes
Cytokines
T-Lymphocytes
Therapeutics
130 Citations (Scopus)

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: Individual participant meta-analysis

Wormser, D., Di Angelantonio, E., Kaptoge, S., Wood, A. M., Gao, P., Sun, Q., Walldius, G., Selmer, R., Monique Verschuren, W. M., Bueno-de-Mesquita, H. B., Engström, G., Ridker, P. M., Njølstad, I., Iso, H., Holme, I., Giampaoli, S., Tunstall-Pedoe, H., Gaziano, J. M., Brunner, E., Kee, F. & 246 others, Tosetto, A., Meisinger, C., Brenner, H., Ducimetiere, P., Whincup, P. H., Tipping, R. W., Ford, I., Cremer, P., Hofman, A., Wilhelmsen, L., Clarke, R., de Boer, I. H., Jukema, J. W., Ibañez, A. M., Lawlor, D. A., D'Agostino, R. B., Rodriguez, B., Casiglia, E., Stehouwer, C. D. A., Simons, L. A., Nietert, P. J., Barrett-Connor, E., Panagiotakos, D. B., Björkelund, C., Strandberg, T. E., Wassertheil-Smoller, S., Blazer, D. G., Meade, T. W., Welin, L., Svärdsudd, K., Woodward, M., Nissinen, A., Kromhout, D., Jørgensen, T., Tilvis, R. S., Guralnik, J. M., Rosengren, A., Taylor, J. O., Kiechl, S., Dagenais, G. R., Fowkes, F. G. R., Wallace, R. B., Khaw, K. T., Shaffer, J. A., Visser, M., Kauhanen, J., Salonen, J. T., Gallacher, J., Ben-Shlomo, Y., Kitamura, A., Sundström, J., Wennberg, P., Kiyohara, Y., Daimon, M., de la Cámara, A. G., Cooper, J. A., Onat, A., Devereux, R., Mukamal, K. J., Dankner, R., Knuiman, M. W., Crespo, C. J., Gansevoort, R. T., Goldbourt, U., Nordestgaard, B. G., Shaw, J. E., Mussolino, M., Nakagawa, H., Fletcher, A., Kuller, L. H., Gillum, R. F., Gudnason, V., Assmann, G., Wald, N., Jousilahti, P. R., Greenland, P., Trevisan, M., Ulmer, H., Butterworth, A. S., Folsom, A. R., Davey-Smith, G., Hu, F. B., Danesh, J., Simpson, L. M., Jungner, I., Demerath, E. W., Franceschini, N., Lutsey, P. L., Pitsavos, C., Chrysohoou, C., Stefanadis, C., Atkins, R., Zimmet, P. Z., Barr, E. L. M., Wannamethee, S. G., Morris, R. W., Willeit, J., Weger, S., Oberhollenzer, F., Ebrahim, S., Yarnell, J. W. G., Tikhonoff, V., Shay, C. M., Garside, D. B., Sutherland, S. E., Bachman, D. L., Keil, J. E., Kizer, J. R., Psaty, B. M., Tybjærg-Hansen, A., Jensen, G. B., Schnohr, P., Palmieri, L., Panico, S., Pilotto, L., Vanuzzo, D., Simons, J., McCallum, J., Friedlander, Y., Phillips, C. L., Kohout, F. J., Cornoni-Huntley, J. C., Wareham, N. J., Schöttker, B., Müller, H., Rothenbacher, D., Jansson, J. H., Donfrancesco, C., Vartiainen, E., Harald, K., Salomaa, V., Vasan, R. S., Fox, C. S., Pencina, M. J., Oizumi, T., Kayama, T., Kato, T., Bladbjerg, E. M., Møller, L., Jespersen, J., Chetrit, A., Lubin, F., Eriksson, H., Lappas, G., Bengtsson, C., Lissner, L., Nagel, D., Miettinen, T. A., Arima, H., Doi, Y., Ninomiya, T., Dekker, J. M., Nijpels, G., Rimm, E. B., Willett, W. C., Yamagishi, K., Noda, H., Kurl, S., Tuomainen, T. P., Poppelaars, J. L., Deeg, D. J. H., De Stavola, B. L., Hedblad, B., Nilsson, P., Blokstra, A., Shea, S. J., Thorand, B., Koenig, W., Döring, A., Nitsch, D., Grandits, G., Tverdal, A., Nystad, W., Manson, J. E., Hankinson, S. E., Bauer, K. A., Davidson, K. W., Kirkland, S., Shimbo, D., Sato, S., Miura, K., Sakurai, M., Jouven, X., Bakker, S. J. L., van der Harst, P., Hillege, H. L., Garcia-Palmieri, M. R., Amouyel, P., Arveiler, D., Ferrières, J., Schulte, H., de Craen, A. J. M., Sattar, N., Stott, D. J., Cantin, B., Lamarche, B., Després, J. P., Bergstrom, J., Bettencourt, R. R., Buisson, C., Aspelund, T., Sigurdsson, G., Thorsson, B., Ikram, M. A., Tiemeier, H., Witteman, J. C. M., Tavendale, R., Lowe, G. D. O., Yeh, J. L., Ali, T., Calhoun, D., Can, G., Nakamura, K., Morikawa, Y., Mathiesen, E. B., Løchen, M. L., Wilsgaard, T., Ingelsson, E., Michaëlsson, K., Cederholm, T., Buring, J., Diem, G., Concin, H., Rodeghiero, F., Marmot, M., Kivimaki, M. S. M., Robertson, M., Feskens, E., Geleijnse, J. M., Kromhout, D., Walker, M., Watson, S., Alexander, M., Franco, O. H., Gobin, R., Haycock, P., Kaptoge, S., Seshasai, S. R. K., Lewington, S., Pennells, L., Rapsomaniki, E., Sarwar, N., Thompson, A., Thompson, S. G., White, I. R. & Zhao, X., Oct 1 2012, In : International Journal of Epidemiology. 41, 5, p. 1419-1433 15 p.

Research output: Contribution to journalArticle

Blood Vessels
Meta-Analysis
Cause of Death
Morbidity
Chronic Obstructive Pulmonary Disease

Advanced glycation end products are associated with immature angiogenesis and peritoneal dysfunction in patients on peritoneal dialysis

Nakano, T., Mizumasa, T., Kuroki, Y., Eriguchi, M., Yoshida, H., Taniguchi, M., Masutani, K., Tsuruya, K. & Kitazono, T., Jan 1 2020, In : Peritoneal Dialysis International. 40, 1, p. 67-75 9 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Peritoneum
Peritoneal Dialysis
Dialysis Solutions
Creatinine
4 Citations (Scopus)
Dementia
Registries
Stroke
Propensity Score
Logistic Models
5 Citations (Scopus)

A first report of East Asian students' perception of progress testing: a focus group study

Matsuyama, Y., Muijtjens, A. M. M., Kikukawa, M., Stalmeijer, R., Murakami, R., Ishikawa, S. & Okazaki, H., Sep 22 2016, In : BMC Medical Education. 16, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

study group
student
learning
teacher
school
13 Citations (Scopus)

A framework for quantifying net benefits of alternative prognostic models

Rapsomaniki, E., White, I. R., Wood, A. M., Thompson, S. G., Tipping, R. W., Ford, C. E., Simpson, L. M., Folsom, A. R., Chambless, L. E., Panagiotakos, D. B., Pitsavos, C., Chrysohoou, C., Stefanadis, C., Knuiman, M., Whincup, P. H., Wannamethee, S. G., Morris, R. W., Kiechl, S., Willeit, J., Oberhollenzer, F. & 166 others, Mayr, A., Wald, N., Lawlor, D. A., Yarnell, J. W., Gallacher, J., Casiglia, E., Tikhonoff, V., Nietert, P. J., Sutherland, S. E., Bachman, D. L., Keil, J. E., Cushman, M., Tracy, R., Tybjærg-Hansen, A., Nordestgaard, B. G., Frikke-Schmidt, R., Giampaoli, S., Palmieri, L., Panico, S., Vanuzzo, D., Pilotto, L., Gómez de la Cámara, A., Gómez Gerique, J. A., Simons, L., McCallum, J., Friedlander, Y., Lee, A. J., Taylor, J., Guralnik, J. M., Wallace, R., Guralnik, J. M., Blazer, D. G., Guralnik, J. M., Guralnik, J. M., Khaw, K. T., Schöttker, B., Müller, H., Rothenbacher, D., Jansson, J. H., Wennberg, P., Nissinen, A., Donfrancesco, C., Salomaa, V., Harald, K., Jousilahti, P., Vartiainen, E., Woodward, M., D'Agostino, R. B., Wolf, P. A., Vasan, R. S., Pencina, M. J., Bladbjerg, E. M., Jørgensen, T., Møller, L., Jespersen, J., Dankner, R., Chetrit, A., Lubin, F., Rosengren, A., Lappas, G., Eriksson, H., Björkelund, C., Lissner, L., Bengtsson, C., Nagel, D., Kiyohara, Y., Arima, H., Doi, Y., Ninomiya, T., Rodriguez, B., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Iso, H., Kitamura, A., Yamagishi, K., Noda, H., Goldbourt, U., Kauhanen, J., Salonen, J. T., Cooper, J. A., Verschuren, W. M. M., Blokstra, A., Cushman, M., Folsom, A. R., Shea, S., Döring, A., Meisinger, C., Verschuren, W. M. M., Blokstra, A., Bueno-de-Mesquita, H. B., Rosengren, A., Lappas, G., Kuller, L. H., Grandits, G., Gillum, R. F., Mussolino, M., Cooper, J. A., Bauer, K. A., Kirkland, S., Shaffer, J., Korin, M. R., Kitamura, A., Iso, H., Sato, S., Amouyel, P., Arveiler, D., Evans, A., Ferrières, J., Schulte, H., Assmann, G., Westendorp, R. G., Buckley, B. M., Packard, C. J., Sattar, N., Cantin, B., Després, J. P., Dagenais, G. R., Barrett-Connor, E., Wingard, D. L., Bettencourt, R., Gudnason, V., Aspelund, T., Sigurdsson, G., Thorsson, B., Witteman, J., Kardys, I., Tiemeier, H., Hofman, A., Tunstall-Pedoe, H., Tavendale, R., Lowe, G. D. O., Woodward, M., Howard, B. V., Zhang, Y., Best, L., Umans, J., Ben-Shlomo, Y., Davey-Smith, G., Njølstad, I., Wilsgaard, T., Ingelsson, E., Lind, L., Giedraitis, V., Lannfelt, L., Gaziano, J. M., Stampfer, M., Ridker, P., Gaziano, J. M., Ridker, P., Wassertheil-Smoller, S., Manson, J. E., Marmot, M., Clarke, R., Fletcher, A., Brunner, E., Shipley, M., Ridker, P., Buring, J., Shepherd, J., Cobbe, S. M., Ford, I., Robertson, M., Marín Ibañez, A., Feskens, E. J. M. & Kromhout, D., Jan 30 2012, In : Statistics in Medicine. 31, 2, p. 114-130 17 p.

Research output: Contribution to journalArticle

Health
Alternatives
Economics
Cost-Benefit Analysis
Cardiovascular Diseases
38 Citations (Scopus)

A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis

Horiuchi, T., Kiyohara, C., Tsukamoto, H., Sawabe, T., Furugo, I., Yoshizawa, S., Ueda, A., Tada, Y., Nakamura, T., Kimoto, Y., Mitoma, H., Harashima, S., Yoshizawa, S., Shimoda, T., Okamura, S., Nagasawa, K. & Harada, M., Mar 1 2007, In : Annals of the Rheumatic Diseases. 66, 3, p. 320-324 5 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type II
Polymorphism
Systemic Lupus Erythematosus
Meta-Analysis
Case-Control Studies
36 Citations (Scopus)

A fusion protein between rac and p67phox (1 - 210) reconstitutes NADPH oxidase with higher activity and stability than the individual components

Miyano, K., Ogasawara, S., Han, C. H., Fukuda, H. & Tamura, M., Nov 20 2001, In : Biochemistry. 40, 46, p. 14089-14097 9 p.

Research output: Contribution to journalArticle

rac GTP-Binding Proteins
NADPH Oxidase
Fusion reactions
Chemical activation
Proteins
8 Citations (Scopus)

A genome-wide association study of late-onset Alzheimer's disease in a Japanese population

Hirano, A., Ohara, T., Takahashi, A., Aoki, M., Fuyuno, Y., Ashikawa, K., Morihara, T., Takeda, M., Kamino, K., Oshima, E., Okahisa, Y., Shibata, N., Arai, H., Akatsu, H., Ikeda, M., Iwata, N., Ninomiya, T., Monji, A., Kitazono, T., Kiyohara, Y. & 2 others, Kubo, M. & Kanba, S., Aug 1 2015, In : Psychiatric Genetics. 25, 4, p. 139-146 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer Disease
Population
Introns
12 Citations (Scopus)

Age-related changes in response of brain stem vessels to opening of ATP-sensitive potassium channels

Toyoda, K., Fujii, K., Takata, Y., Ibayashi, S., Kitazono, T., Nagao, T., Fujikawa, M. & Fujishima, M., Jan 1997, In : Stroke. 28, 1, p. 171-175 5 p.

Research output: Contribution to journalArticle

KATP Channels
Brain Stem
Adenosine Triphosphate
Vasodilator Agents
Basilar Artery
1 Citation (Scopus)

Age-Related Decline in Patient-Reported Outcomes 2 and 5 Years Following Total Hip Arthroplasty

Lalani, A., Lee, Y. Y., Pitta, M., Westrich, G. H. & Lyman, S., Sep 2019, In : Journal of Arthroplasty. 34, 9, p. 1999-2005 7 p.

Research output: Contribution to journalArticle

Hip Osteoarthritis
Arthroplasty
Hip
Recreation
Lower Extremity
1 Citation (Scopus)

Age-Related Functional Decline Following Total Knee Arthroplasty: Risk Adjustment is Mandatory

Pitta, M., Khoshbin, A., Lalani, A., Lee, L. Y., Woo, P., Westrich, G. H. & Lyman, S., Feb 2019, In : Journal of Arthroplasty. 34, 2, p. 228-234 7 p.

Research output: Contribution to journalArticle

Risk Adjustment
Knee Replacement Arthroplasties
Lower Extremity
Activities of Daily Living
Pain
10 Citations (Scopus)

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN)

the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Jan 1 2017, In : Journal of epidemiology. 27, 3, p. 123-129 7 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Japan
Cardiovascular Diseases
Mortality
Research

A greater reduction in the distal femoral anterior condyle improves flexion after total knee arthroplasty in patients with osteoarthritis

Nishitani, K., Hatada, R., Kuriyama, S., Lyman, S. L., Nakamura, S., Ito, H. & Matsuda, S., Dec 2019, In : Knee. 26, 6, p. 1364-1371 8 p.

Research output: Contribution to journalArticle

Knee Replacement Arthroplasties
Thigh
Osteoarthritis
Knee
Bone and Bones
34 Citations (Scopus)

A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter

Umeno, J., Hisamatsu, T., Esaki, M., Hirano, A., Kubokura, N., Asano, K., Kochi, S., Yanai, S., Fuyuno, Y., Shimamura, K., Hosoe, N., Ogata, H., Watanabe, T., Aoyagi, K., Ooi, H., Watanabe, K., Yasukawa, S., Hirai, F., Matsui, T., Iida, M. & 6 others, Yao, T., Hibi, T., Kosaki, K., Kanai, T., Kitazono, T. & Matsumoto, T., Nov 2015, In : PLoS genetics. 11, 11, e1005581.

Research output: Contribution to journalArticle

digestive system diseases
prostaglandins
Prostaglandins
transporters
mutation
6 Citations (Scopus)

A J-shaped association between serum uric acid levels and poor renal survival in female patients with IgA nephropathy

Matsukuma, Y., Masutani, K., Tanaka, S., Tsuchimoto, A., Fujisaki, K., Torisu, K., Katafuchi, R., Hirakata, H., Tsuruya, K. & Kitazono, T., Mar 1 2017, In : Hypertension Research. 40, 3, p. 291-297 7 p.

Research output: Contribution to journalArticle

Uric Acid
Immunoglobulin A
Kidney
IGA Glomerulonephritis
Chronic Kidney Failure
534 Citations (Scopus)

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes

Ninomiya, T., Perkovic, V., De Galan, B. E., Zoungas, S., Pillai, A., Jardine, M., Patel, A., Cass, A., Neal, B., Poulter, N., Mogensen, C. E., Cooper, M., Marre, M., Williams, B., Hamet, P., Mancia, G., Woodward, M., MacMahon, S. & Chalmers, J., Aug 1 2009, In : Journal of the American Society of Nephrology. 20, 8, p. 1813-1821 9 p.

Research output: Contribution to journalArticle

Albuminuria
Albumins
Creatinine
Kidney
Type 2 Diabetes Mellitus
11 Citations (Scopus)

Albuminuria as a risk factor for peripheral arterial disease in a general population - The Hisayama Study

Usui, T., Ninomiya, T., Nagata, M., Doi, Y., Hata, J., Fukuhara, M. & Kiyohara, Y., Aug 31 2011, In : Journal of atherosclerosis and thrombosis. 18, 8, p. 705-712 8 p.

Research output: Contribution to journalArticle

Albuminuria
Peripheral Arterial Disease
Albumins
Creatinine
Population
4 Citations (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
3 Citations (Scopus)

Alcohol consumption and lung cancer risk among Japanese: a meta-analysis.

Uehara, Y. & Kiyohara, C., May 1 2010, In : Fukuoka igaku zasshi = Hukuoka acta medica. 101, 5, p. 101-108 8 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Meta-Analysis
Lung Neoplasms
Epidemiologic Studies
Smoking
13 Citations (Scopus)

Alcohol drinking and risk of Parkinson's disease: A case-control study in Japan

Fukushima, W., Miyake, Y., Tanaka, K., Sasaki, S., Kiyohara, C., Tsuboi, Y., Yamada, T., Oeda, T., Miki, T., Kawamura, N., Sakae, N., Fukuyama, H., Hirota, Y. & Nagai, M., Nov 5 2010, In : BMC neurology. 10, 111.

Research output: Contribution to journalArticle

Alcohol Drinking
Parkinson Disease
Case-Control Studies
Japan
Alcohols
17 Citations (Scopus)

Aldosterone-and-salt-induced cardiac fibrosis is independent from angiotensin II type 1a receptor signaling in mice

Kagiyama, S., Matsumura, K., Fukuhara, M., Sakagami, K., Fujii, K. & Iida, M., Oct 1 2007, In : Hypertension Research. 30, 10, p. 979-989 11 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Aldosterone
Fibrosis
Salts
Connective Tissue Growth Factor
42 Citations (Scopus)

Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: The Hisayama study

Shibata, M., Ninomiya, T., Jensen, M. P., Anno, K., Yonemoto, K., Makino, S., Iwaki, R., Yamashiro, K., Yoshida, T., Imada, Y., Kubo, C., Kiyohara, Y., Sudo, N. & Hosoi, M., Mar 12 2014, In : PloS one. 9, 3, e90984.

Research output: Contribution to journalArticle

Affective Symptoms
Chronic Pain
pain
Population
Medical problems
18 Citations (Scopus)

All-cause versus complication-specific readmission following total knee arthroplasty

D'Apuzzo, M., Westrich, G., Hidaka, C., Pan, T. J. & Lyman, S., Jan 1 2017, In : Journal of Bone and Joint Surgery - American Volume. 99, 13, p. 1093-1103 11 p.

Research output: Contribution to journalArticle

Knee Replacement Arthroplasties
Odds Ratio
Confidence Intervals
Patient Readmission
Medicaid
25 Citations (Scopus)

A low ankle brachial index is associated with an increased risk of cardiovascular disease: The hisayama study

Kojima, I., Ninomiya, T., Hata, J., Fukuhara, M., Hirakawa, Y., Mukai, N., Yoshida, D., Kitazono, T. & Kiyohara, Y., Jan 1 2014, In : Journal of atherosclerosis and thrombosis. 21, 9, p. 966-973 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Cardiovascular Diseases
Confidence Intervals
Blood Pressure
Independent Living
28 Citations (Scopus)

Altered cerebrovascular response to a potassium channel opener in hypertensive rats

Takaba, H., Nagao, T., Ibayashi, S., Kitazono, T., Fujii, K. & Fujishima, M., Jul 1996, In : Hypertension. 28, 1, p. 143-146 4 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Potassium Channels
KATP Channels
Inbred WKY Rats
Cilazapril
118 Citations (Scopus)

Altered expression of diabetes-related genes in Alzheimer's disease brains: The Hisayama study

Hokama, M., Oka, S., Leon, J., Ninomiya, T., Honda, H., Sasaki, K., Iwaki, T., Ohara, T., Sasaki, T., LaFerla, F. M., Kiyohara, Y. & Nakabeppu, Y., Sep 2014, In : Cerebral Cortex. 24, 9, p. 2476-2488 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Brain
Genes
Diabetes Mellitus
Brain Diseases
4 Citations (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
4 Citations (Scopus)

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

Tsuchihashi, T., Tsukashima, A., Matsumura, K., Abe, I., Tominaga, M., Nakao, Y., Kobayashi, K. & Fujishima, M., Sep 1 1991, In : European Journal of Clinical Pharmacology. 41, 3, p. 255-257 3 p.

Research output: Contribution to journalArticle

nilvadipine
Ambulatory Blood Pressure Monitoring
Calcium
Blood Pressure
Heart Rate

A medical record peer-review system to evaluate residents’ clinical competence: Criterion validity analysis

Kameoka, J., Kikukawa, M., Kobayashi, D., Okubo, T., Ishii, S. & Kagaya, Y., Aug 2019, In : Tohoku Journal of Experimental Medicine. 248, 4, p. 253-260 8 p.

Research output: Contribution to journalArticle

Open Access
Peer Review
Clinical Competence
Medical Records
Medical education
Supervisory personnel
49 Citations (Scopus)

Amelioration of autoimmune nephritis by imatinib in MRL/lpr mice

Sadanaga, A., Nakashima, H., Masutani, K., Miyake, K., Shimizu, S., Igawa, T., Sugiyama, N., Niiro, H., Hirakata, H. & Harada, M., Dec 1 2005, In : Arthritis and rheumatism. 52, 12, p. 3987-3996 10 p.

Research output: Contribution to journalArticle

Inbred MRL lpr Mouse
Nephritis
Glomerulonephritis
Platelet-Derived Growth Factor Receptors
Lupus Nephritis
13 Citations (Scopus)

Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes

Nakamura, K., Kamouchi, M., Kitazono, T., Kuroda, J., Shono, Y., Hagiwara, N., Ago, T., Ooboshi, H., Ibayashi, S. & Iida, M., May 1 2009, In : Microvascular Research. 77, 3, p. 327-334 8 p.

Research output: Contribution to journalArticle

Pericytes
Amiloride
Hydrogen Peroxide
Sodium-Hydrogen Antiporter
Acid Sensing Ion Channels
9 Citations (Scopus)

A model teaching session for the hypothesis-driven physical examination

Nishigori, H., Masuda, K., Kikukawa, M., Kawashima, A., Yudkowsky, R., Bordage, G. & Otaki, J., May 1 2011, In : Medical Teacher. 33, 5, p. 410-417 8 p.

Research output: Contribution to journalArticle

Physical Examination
Teaching
examination
Students
diagnostic
18 Citations (Scopus)

Amplification of IL-21 signalling pathway through bruton's tyrosine kinase in human B cell activation

Wang, S. P., Iwata, S., Nakayamada, S., Niiro, H., Jabbarzadeh-Tabrizi, S., Kondo, M., Kubo, S., Yoshikawa, M. & Tanaka, Y., May 5 2015, In : Rheumatology (United Kingdom). 54, 8, p. 1488-1497 10 p., keu532.

Research output: Contribution to journalArticle

B-Lymphocytes
Phosphorylation
interleukin-21
Agammaglobulinaemia tyrosine kinase
Genetic Recombination
21 Citations (Scopus)

Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation

Iwata, S., Yamaoka, K., Niiro, H., Nakano, K., Wang, S. P., Akashi, K. & Tanaka, Y., Jun 2012, In : Journal of Allergy and Clinical Immunology. 129, 6, p. 1594-1601.e2

Research output: Contribution to journalArticle

Toll-Like Receptors
B-Lymphocytes
TNF Receptor-Associated Factor 6
B-Lymphocyte Subsets
human SYK protein
7 Citations (Scopus)

A multicenter, prospective, observational study of warfarin-associated intracerebral hemorrhage: The SAMURAI-WAICH study

Osaki, M., Koga, M., Maeda, K., Hasegawa, Y., Nakagawara, J., Furui, E., Todo, K., Kimura, K., Shiokawa, Y., Okada, Y., Okuda, S., Kario, K., Yamagami, H., Minematsu, K., Kitazono, T. & Toyoda, K., Dec 15 2015, In : Journal of the Neurological Sciences. 359, 1-2, p. 72-77 6 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Warfarin
Observational Studies
Prospective Studies
Anticoagulants
6 Citations (Scopus)

An advanced case of indium lung disease with progressive emphysema

Nakano, M., Tanaka, A., Hirata, M., Kumazoe, H., Wakamatsu, K., Kamada, D. & Omae, K., Jan 1 2016, In : Journal of Occupational Health. 58, 5, p. 477-481 5 p.

Research output: Contribution to journalArticle

Indium
Emphysema
Lung Diseases
Respiratory Function Tests
Vital Capacity
34 Citations (Scopus)

Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells

Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., May 1 2011, In : Rheumatology. 50, 5, p. 944-952 9 p., keq414.

Research output: Contribution to journalArticle

Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Stem Cells
Sclerosis
2 Citations (Scopus)

Analysis of Japanese articles about suicides involving charcoal burning or hydrogen sulfide gas

Nabeshima, Y., Onozuka, D., Kitazono, T. & Hagihara, A., Oct 2016, In : International journal of environmental research and public health. 13, 10, 1013.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Charcoal
Suicide
Gases
Newspapers
7 Citations (Scopus)
Ambulances
Particulate Matter
Japan
Emergencies
Cardiovascular Diseases
29 Citations (Scopus)

An ATP-sensitive potassium channel activator reduces infarct volume in focal cerebral ischemia in rats

Takaba, H., Nagao, T., Yao, H., Kitazono, T., Ibayashi, S. & Fujishima, M., Oct 18 1997, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 273, 2 42-2, p. R583-R586

Research output: Contribution to journalArticle

Cerebrovascular Circulation
KATP Channels
Brain Ischemia
Control Groups
Laser-Doppler Flowmetry
1 Citation (Scopus)

A new aspect of arsenic, an old poison

Hirata, M., Sep 1999, In : Fukuoka igaku zasshi = Hukuoka acta medica. 90, 9, p. 347-352 6 p.

Research output: Contribution to journalArticle

Arsenic Poisoning
Poisons
Arsenic
7 Citations (Scopus)

A new role of Pro-73 of p47phox in the activation of neutrophil NADPH oxidase

Nagasawa, T., Ebisu, K., Inoue, Y., Miyano, K. & Tamura, M., Aug 1 2003, In : Archives of Biochemistry and Biophysics. 416, 1, p. 92-100 9 p.

Research output: Contribution to journalArticle

Neutrophil Activation
NADPH Oxidase
Substitution reactions
Chemical activation
Mutation
3 Citations (Scopus)

A new type of O2--generating tool for oxidative stress studies by remodeling neutrophil NADPH oxidase

Tamura, M., Nagasawa, T., Tange, T., Miyano, K., Kobayashi, S. I., Nakai, T. & Miura, S., Dec 6 2005, In : Journal of Biotechnology. 120, 4, p. 421-429 9 p.

Research output: Contribution to journalArticle

Oxidative stress
NADPH Oxidase
Oxidative Stress
Neutrophils
Enzymes
445 Citations (Scopus)

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. I. & Nakayama, K., May 4 1999, In : EMBO Journal. 18, 9, p. 2401-2410 10 p.

Research output: Contribution to journalArticle

F-Box Proteins
Proteolysis
Catenins
Ubiquitin
Ubiquitination
45 Citations (Scopus)

Angiopoietin-like protein 2 and risk of type 2 diabetes in a general Japanese population: The Hisayama study

Doi, Y., Ninomiya, T., Hirakawa, Y., Takahashi, O., Mukai, N., Hata, J., Iwase, M., Kitazono, T., Oike, Y. & Kiyohara, Y., Jan 1 2013, In : Diabetes care. 36, 1, p. 98-100 3 p.

Research output: Contribution to journalArticle

Angiopoietins
C-Reactive Protein
Type 2 Diabetes Mellitus
Independent Living
Serum