Department of Medical Education

Research Output 1983 2019

2015
24 Citations (Scopus)

Midlife and late-life smoking and risk of dementia in the community: The Hisayama study

Ohara, T., Ninomiya, T., Hata, J., Ozawa, M., Yoshida, D., Mukai, N., Nagata, M., Iwaki, T., Kitazono, T., Kanba, S. & Kiyohara, Y., Nov 2015, In : Journal of the American Geriatrics Society. 63, 11, p. 2332-2339 8 p.

Research output: Contribution to journalArticle

Dementia
Smoking
Vascular Dementia
Alzheimer Disease
Confidence Intervals
21 Citations (Scopus)

Nonconvulsive partial status epilepticus mimicking recurrent infarction revealed by diffusion-weighted and arterial spin labeling perfusion magnetic resonance images

Kanazawa, Y., Morioka, T., Arakawa, S., Furuta, Y., Nakanishi, A. & Kitazono, T., Jan 1 2015, In : Journal of Stroke and Cerebrovascular Diseases. 24, 4, p. 731-738 8 p.

Research output: Contribution to journalArticle

Status Epilepticus
Infarction
Magnetic Resonance Spectroscopy
Perfusion
Stroke

Onset of reversible flaccid quadriplegia during treatment of thyrotoxic crisis

Mizokam, T., Fukui, T., Imoto, H., Fujii, H., Sato, Y., Nunoi, K. & Okamura, K., Jan 1 2015, In : Internal Medicine. 54, 4, p. 421-425 5 p.

Research output: Contribution to journalArticle

Thyroid Crisis
Quadriplegia
Antithyroid Agents
Thyrotoxicosis
Multiple Organ Failure
12 Citations (Scopus)
Chronic Pain
Mothers
Population
Odds Ratio
Object Attachment
1 Citation (Scopus)

Patterns of Japanese Diet and Risk of Dementia

Ninomiya, T., Jun 22 2015, In : Current Nutrition Reports. 4, 2, p. 136-142 7 p., 4.

Research output: Contribution to journalReview article

dementia
Dementia
Diet
diet
dairy products
18 Citations (Scopus)

Phosphate Binders Prevent Phosphate-Induced Cellular Senescence of Vascular Smooth Muscle Cells and Vascular Calcification in a Modified, Adenine-Based Uremic Rat Model

Yamada, S., Tatsumoto, N., Tokumoto, M., Noguchi, H., Ooboshi, H., Kitazono, T. & Tsuruya, K., Mar 13 2015, In : Calcified Tissue International. 96, 4, p. 347-358 12 p.

Research output: Contribution to journalArticle

Vascular Calcification
Cell Aging
Adenine
Vascular Smooth Muscle
Smooth Muscle Myocytes
2 Citations (Scopus)

Phosphorylation of p27Kip1on serine 10 is required for its binding to CRM1 and nuclear export

Ishida, N., Hara, T., Kamura, T., Yoshida, M., Nakayama, K. & Nakayama, K. I., Mar 13 2015, In : Journal of Biological Chemistry. 290, 11, 1 p.

Research output: Contribution to journalComment/debate

Cell Nucleus Active Transport
Serine
Phosphorylation
3 Citations (Scopus)

Prognostic impact of serum bilirubin level on long-term renal survival in IgA nephropathy

Tanaka, S., Ninomiya, T., Masutani, K., Nagata, M., Tsuchimoto, A., Tsuruya, K. & Kitazono, T., Dec 1 2015, In : Clinical and Experimental Nephrology. 19, 6, p. 1062-1070 9 p.

Research output: Contribution to journalArticle

Bilirubin
Immunoglobulin A
Kidney
Chronic Kidney Failure
Serum
6 Citations (Scopus)

Pulmonary effects in workers exposed to indium metal: A cross-sectional study

Nakano, M., Tanaka, A., Hirata, M., Iwasawa, S. & Omae, K., Jan 1 2015, In : Journal of Occupational Health. 57, 4, p. 346-352 7 p.

Research output: Contribution to journalArticle

Indium
Cross-Sectional Studies
Metals
Lung
Serum
3 Citations (Scopus)

Radiation-induced hemorrhagic duodenitis associated with sorafenib treatment

Yanai, S., Nakamura, S., Ooho, A., Nakamura, S., Esaki, M., Azuma, K., Kitazono, T. & Matsumoto, T., Jun 30 2015, In : Clinical Journal of Gastroenterology. 8, 3, p. 116-119 4 p.

Research output: Contribution to journalArticle

Duodenitis
Radiation
Digestive System Endoscopy
Hepatocellular Carcinoma
Hemorrhage
3 Citations (Scopus)
Hypocalcemia
Multiple Myeloma
Chronic Renal Insufficiency
Blood Vessels
Calcium
8 Citations (Scopus)

Relationship between salt intake as estimated by a brief self-administered diet-history questionnaire (BDHQ) and 24-h urinary salt excretion in hypertensive patients

Sakata, S., Tsuchihashi, T., Oniki, H., Tominaga, M., Arakawa, K., Sakaki, M. & Kitazono, T., Aug 8 2015, In : Hypertension Research. 38, 8, p. 560-563 4 p.

Research output: Contribution to journalArticle

Salts
History
Diet
Surveys and Questionnaires
Urine Specimen Collection
18 Citations (Scopus)

Renal denervation has blood pressure-independent protective effects on kidney and heart in a rat model of chronic kidney disease

Eriguchi, M., Tsuruya, K., Haruyama, N., Yamada, S., Tanaka, S., Suehiro, T., Noguchi, H., Masutani, K., Torisu, K. & Kitazono, T., Jan 3 2015, In : Kidney International. 87, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

Denervation
Chronic Renal Insufficiency
Angiotensinogen
Blood Pressure
Kidney
8 Citations (Scopus)

Risk factors for reduced salivary flow rate in a Japanese population: The Hisayama study

Takeuchi, K., Furuta, M., Takeshita, T., Shibata, Y., Shimazaki, Y., Akifusa, S., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., 2015, In : BioMed Research International. 2015, 381821.

Research output: Contribution to journalArticle

Independent Living
Odds Ratio
Flow rate
Confidence Intervals
Serum Albumin
9 Citations (Scopus)

Risk for Complication after Total Joint Arthroplasty at a Center of Excellence: The Impact of Patient Travel Distance

Nwachukwu, B. U., Dy, C. J., Burket, J. C., Padgett, D. E. & Lyman, S., Jun 1 2015, In : Journal of Arthroplasty. 30, 6, p. 1058-1061 4 p.

Research output: Contribution to journalArticle

Arthroplasty
Joints
Orthopedics
Delivery of Health Care
Medicaid
1 Citation (Scopus)

Risk of cancer in the rectal remnant after ileorectal anastomosis in patients with familial adenomatous polyposis: Single center experience

Maehata, Y., Esaki, M., Nakamura, S., Hirahashi, M., Ueki, T., Iida, M., Kitazono, T. & Matsumoto, T., May 1 2015, In : Digestive Endoscopy. 27, 4, p. 471-478 8 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Rectal Neoplasms
Colectomy
Retinal Pigment Epithelium
Incidence
8 Citations (Scopus)

Serum antibody to Porphyromonas gingivalis and periodontitis progression: The Hisayama Study

Takeuchi, K., Furuta, M., Takeshita, T., Shibata, Y., Shimazaki, Y., Akifusa, S., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., Aug 1 2015, In : Journal of Clinical Periodontology. 42, 8, p. 719-725 7 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Periodontitis
Antibodies
Serum
Logistic Models
7 Citations (Scopus)
Dermatomyositis
Interstitial Lung Diseases
Serum
Polymyositis
Protein S
23 Citations (Scopus)

Sex differences in short-term outcomes after acute ischemic stroke: The fukuoka stroke registry

Irie, F., Kamouchi, M., Hata, J., Matsuo, R., Wakisaka, Y., Kuroda, J., Ago, T., Kitazono, T., Ishitsuka, T., Fujimoto, S., Ibayashi, S., Kusuda, K., Arakawa, S., Tamaki, K., Sadoshima, S., Irie, K., Fujii, K., Okada, Y., Yasaka, M., Nagao, T. & 7 others, Ooboshi, H., Omae, T., Toyoda, K., Nakane, H., Sugimori, H., Fukuda, K. & Fukushima, Y., Feb 6 2015, In : Stroke. 46, 2, p. 471-476 6 p.

Research output: Contribution to journalArticle

Sex Characteristics
Registries
Stroke
National Institutes of Health (U.S.)
Japan
16 Citations (Scopus)

Spironolactone ameliorates arterial medial calcification in uremic rats: The role of mineralocorticoid receptor signaling in vascular calcification

Tatsumoto, N., Yamada, S., Tokumoto, M., Eriguchi, M., Noguchi, H., Torisu, K., Tsuruya, K. & Kitazono, T., Jan 1 2015, In : American Journal of Physiology - Renal Physiology. 309, 11, p. F967-F979

Research output: Contribution to journalArticle

Vascular Calcification
Mineralocorticoid Receptors
Spironolactone
Chronic Renal Insufficiency
Hyperphosphatemia
8 Citations (Scopus)

Stage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure

Nonaka, M., Morimoto, S., Murayama, T., Kurebayashi, N., Li, L., Wang, Y. Y., Arioka, M., Yoshihara, T., Takahashi-Yanaga, F. & Sasaguri, T., Jan 5 2015, In : British Journal of Pharmacology. 172, 9, p. 2369-2382 14 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Heart Failure
Sudden Cardiac Death
Sarcoplasmic Reticulum
pimobendan
4 Citations (Scopus)
Indium
Nanoparticles
indium
Suspensions
Plasmas
3 Citations (Scopus)

Systemic aldosterone, but not angiotensin II, plays a pivotal role in the pathogenesis of renal injury in chronic nitric oxide-deficient male rats

Suehiro, T., Tsuruya, K., Ikeda, H., Toyonaga, J., Yamada, S., Noguchi, H., Tokumoto, M. & Kitazono, T., Jul 1 2015, In : Endocrinology. 156, 7, p. 2657-2666 10 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Nitric Oxide
Kidney
NG-Nitroarginine Methyl Ester
2 Citations (Scopus)

Temporal serum creatinine increase and exacerbation of tubulointerstitial inflammation during the first two months in resolving polyomavirus BK nephropathy

Masutani, K., Tsuchimoto, A., Matsukuma, Y., Kurihara, K., Nishiki, T., Kitada, H., Tanaka, M., Kitazono, T. & Tsuruya, K., Jul 1 2015, In : Nephrology. 20, S2, p. 45-50 6 p.

Research output: Contribution to journalArticle

BK Virus
Creatinine
Inflammation
Biopsy
Serum
6 Citations (Scopus)
Surgical Wound Infection
Statistical Models
Japan
Infection
Cross Infection
16 Citations (Scopus)

The potential influence of regionalization strategies on delivery of care for elective total joint arthroplasty

Dy, C. J., Marx, R. G., Ghomrawi, H. M. K., Pan, T. J., Westrich, G. H. & Lyman Stephen, L., Jan 1 2015, In : Journal of Arthroplasty. 30, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

High-Volume Hospitals
Arthroplasty
Joints
Low-Volume Hospitals
Knee Replacement Arthroplasties
3 Citations (Scopus)

Therapeutic strategy for crohn's disease with a loss of response to infliximab: A single-center retrospective study

Nagata, Y., Esaki, M., Umeno, J., Fuyuno, Y., Ikegami, K., Maehata, Y., Asano, K., Moriyama, T., Nakamura, S., Kitazono, T. & Matsumoto, T., Feb 6 2015, In : Digestion. 91, 1, p. 50-56 7 p.

Research output: Contribution to journalArticle

Crohn Disease
Retrospective Studies
Therapeutics
1-morpholinomethyl-tetrahydro-1(1H)-pyrimidinone
Infliximab
5 Citations (Scopus)

Tissue distribution of indium after repeated intratracheal instillations of indium-tin oxide into the lungs of hamsters

Tanaka, A., Hirata, M., Matsumura, N. & Kiyohara, Y., Jan 1 2015, In : Journal of Occupational Health. 57, 2, p. 189-192 4 p.

Research output: Contribution to journalArticle

Indium
Tissue Distribution
Cricetinae
Lung
Spleen
1 Citation (Scopus)

Two cases of ischemic cerebrovascular disease with only memory disturbance as neurological symptom and abnormal MR findings

Mezuki, S., Fujimoto, S., Matsuki, T., Suzuki, S., Ishitsuka, T. & Kitazono, T., Jan 1 2015, In : Clinical Neurology. 55, 3, p. 145-150 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Hippocampus
Magnetic Resonance Angiography
Transesophageal Echocardiography
Atherosclerotic Plaques

Two Year Clinical Outcomes of Total Hip Arthroplasty Are Not Dependent on Femoral Head Composition

Ast, M. P., Lyman Stephen, L., Gorab, A. H., Parkes, N., Boles, J., Lee, Y. Y. & Westrich, G. H., Jul 27 2015, In : HSS Journal. 11, 2, p. 130-135 6 p.

Research output: Contribution to journalArticle

Thigh
Arthroplasty
Hip
Hip Osteoarthritis
Quality of Life
2 Citations (Scopus)

Two Years of Cinacalcet Hydrochloride Treatment Decreased Parathyroid Gland Volume and Serum Parathyroid Hormone Level in Hemodialysis Patients With Advanced Secondary Hyperparathyroidism

Yamada, S., Tokumoto, M., Taniguchi, M., Toyonaga, J., Suehiro, T., Eriguchi, R., Fujimi, S., Ooboshi, H., Kitazono, T. & Tsuruya, K., Aug 1 2015, In : Therapeutic Apheresis and Dialysis. 19, 4, p. 367-377 11 p.

Research output: Contribution to journalArticle

Secondary Hyperparathyroidism
Parathyroid Glands
Parathyroid Hormone
Renal Dialysis
Serum
15 Citations (Scopus)

TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

Nagafuchi, S., Kamada-Hibio, Y., Hirakawa, K., Tsutsu, N., Minami, M., Okada, A., Kai, K., Teshima, M., Moroishi, A., Murakami, Y., Umeno, Y., Yokogawa, Y., Kogawa, K., Izumi, K., Anzai, K., Iwakiri, R., Hamaguchi, K., Sasaki, N., Nohara, S., Yoshida, E. & 16 others, Harada, M., Akashi, K., Yanase, T., Ono, J., Okeda, T., Fujimoto, R., Ihara, K., Hara, T., Kikuchi, Y., Iwase, M., Kitazono, T., Kojima, F., Kono, S., Kurisaki, H., Kondo, S. & Katsuta, H., Jul 1 2015, In : EBioMedicine. 2, 7, p. 744-749 6 p.

Research output: Contribution to journalArticle

Medical problems
Type 1 Diabetes Mellitus
Diabetes Mellitus
Type 2 Diabetes Mellitus
Genes
1 Citation (Scopus)

Ulcerative Colitis Presented as Fever and Bloody Diarrhea at Initiation of Dialysis in an Elderly Patient with End-Stage Kidney Disease

Yamada, S., Kanazawa, Y., Nakamura, N., Masutani, K., Esaki, M., Kitazono, T. & Tsuruya, K., Jan 1 2015, In : Case Reports in Medicine. 2015, 725205.

Research output: Contribution to journalArticle

Ulcerative Colitis
Chronic Kidney Failure
Dialysis
Diarrhea
Fever
11 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Population
Spirometry
ROC Curve
Surveys and Questionnaires
2 Citations (Scopus)

Variability of urinary salt excretion estimated by spot urine in treated hypertensive patients

Arakawa, K., Sakaki, M., Sakata, S., Oniki, H., Tominaga, M. & Tsuchihashi, T., Aug 18 2015, In : Clinical and Experimental Hypertension. 37, 6, p. 445-448 4 p.

Research output: Contribution to journalArticle

Salts
Urine
Blood Pressure
Outpatients
Observation
427 Citations (Scopus)

Worldwide access to treatment for end-stage kidney disease: A systematic review

Liyanage, T., Ninomiya, T., Jha, V., Neal, B., Patrice, H. M., Okpechi, I., Zhao, M. H., Lv, J., Garg, A. X., Knight, J., Rodgers, A., Gallagher, M., Kotwal, S., Cass, A. & Perkovic, V., May 16 2015, In : The Lancet. 385, 9981, p. 1975-1982 8 p.

Research output: Contribution to journalArticle

Renal Replacement Therapy
Chronic Kidney Failure
Therapeutics
Health Care Costs
Observational Studies
24 Citations (Scopus)
NF-E2-Related Factor 2
Heme Oxygenase-1
Oxidative stress
NF-kappa B
Keratinocytes
2014
1 Citation (Scopus)

[Brain pericyte in health and cerebrovascular diseases]

Ago, T. & Kitazono, T., Jun 1 2014, In : Fukuoka igaku zasshi = Hukuoka acta medica. 105, 6, p. 125-130 6 p.

Research output: Contribution to journalReview article

Cerebrovascular Disorders
Pericytes
Blood-Brain Barrier
Stem Cells
Health
47 Citations (Scopus)

ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack

Kiyohara, T., Kamouchi, M., Kumai, Y., Ninomiya, T., Hata, J., Yoshimura, S., Ago, T., Okada, Y. & Kitazono, T., Feb 1 2014, In : Stroke. 45, 2, p. 418-425 8 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Stroke
Proportional Hazards Models
Carotid Stenosis
Neuroimaging
1 Citation (Scopus)

A case of CNS-limited ANCA-associated vasculitis presenting as recurrent ischemic stroke

Wakisaka, K., Hagiwara, N., Kanazawa, Y., Arakawa, S., Ago, T. & Kitazono, T., Jan 1 2014, In : Clinical Neurology. 54, 5, p. 429-433 5 p.

Research output: Contribution to journalArticle

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Infarction
Stroke
Fever of Unknown Origin
Antineutrophil Cytoplasmic Antibodies
3 Citations (Scopus)

A case of intravascular large B-cell lymphoma (IVLBCL) with central nervous system symptoms diagnosed by renal biopsy

Kanazawa, Y., Hagiwara, N., matsuo, R., Arakawa, S., Ago, T. & Kitazono, T., Jan 1 2014, In : Clinical Neurology. 54, 6, p. 484-488 5 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Parietal Lobe
Central Nervous System
Kidney
Biopsy
38 Citations (Scopus)

Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis

Arioka, M., Takahashi-Yanaga, F., Sasaki, M., Yoshihara, T., Morimoto, S., Hirata, M., Mori, Y. & Sasaguri, T., Aug 15 2014, In : Biochemical Pharmacology. 90, 4, p. 397-405 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Bone Regeneration
Lithium
Osteogenesis
Bone
38 Citations (Scopus)

Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: The Hisayama study

Shibata, M., Ninomiya, T., Jensen, M. P., Anno, K., Yonemoto, K., Makino, S., Iwaki, R., Yamashiro, K., Yoshida, T., Imada, Y., Kubo, C., Kiyohara, Y., Sudo, N. & Hosoi, M., Mar 12 2014, In : PloS one. 9, 3, e90984.

Research output: Contribution to journalArticle

Affective Symptoms
Chronic Pain
pain
Population
Medical problems
24 Citations (Scopus)

A low ankle brachial index is associated with an increased risk of cardiovascular disease: The hisayama study

Kojima, I., Ninomiya, T., Hata, J., Fukuhara, M., Hirakawa, Y., Mukai, N., Yoshida, D., Kitazono, T. & Kiyohara, Y., Jan 1 2014, In : Journal of atherosclerosis and thrombosis. 21, 9, p. 966-973 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Cardiovascular Diseases
Confidence Intervals
Blood Pressure
Independent Living
116 Citations (Scopus)

Altered expression of diabetes-related genes in Alzheimer's disease brains: The Hisayama study

Hokama, M., Oka, S., Leon, J., Ninomiya, T., Honda, H., Sasaki, K., Iwaki, T., Ohara, T., Sasaki, T., LaFerla, F. M., Kiyohara, Y. & Nakabeppu, Y., Sep 2014, In : Cerebral Cortex. 24, 9, p. 2476-2488 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Brain
Genes
Diabetes Mellitus
Brain Diseases
48 Citations (Scopus)

A meta-analysis of the evidence on the impact of prenatal and early infancy exposures to mercury on autism and attention deficit/hyperactivity disorder in the childhood

Yoshimasu, K., Kiyohara, C., Takemura, S. & Nakai, K., Sep 2014, In : NeuroToxicology. 44, p. 121-131 11 p.

Research output: Contribution to journalReview article

Thimerosal
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Mercury
Meta-Analysis
9 Citations (Scopus)

Angiotensin-converting enzyme inhibitor usage and acute kidney injury: A secondary analysis of RENAL study outcomes

RENAL STUDY INVESTIGATORS & ANZICS CLINICAL TRIALS GROUP, Oct 1 2014, In : Nephrology. 19, 10, p. 617-622 6 p.

Research output: Contribution to journalArticle

Angiotensin-Converting Enzyme Inhibitors
Acute Kidney Injury
Outcome Assessment (Health Care)
Mortality
Renal Replacement Therapy
11 Citations (Scopus)
Peptidyl-Dipeptidase A
Hypercholesterolemia
Polymorphism
Coronary Disease
Genes
6 Citations (Scopus)

An instrument for evaluating clinical teaching in Japan: Content validity and cultural sensitivity

Kikukawa, M., Stalmeijer, R. E., Emura, S., Roff, S. & Scherpbier, A. J. J. A., Aug 28 2014, In : BMC Medical Education. 14, 1, 179.

Research output: Contribution to journalArticle

Japan
Teaching
teacher
cultural factors
evaluation