Department of Medical Education

Research Output

2007

Mechanisms of oxidative stress-induced calcium signaling in human CNS pericytes

Kamouchi, M., Kitazono, T., Kuroda, J., Nakamura, K., Shono, Y., Hagiwara, N., Ooboshi, H., Ibayashi, S. & Iida, M., Nov 13 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1, p. BP39-02M

Research output: Contribution to journalArticle

NAD(P)H oxidase p22phox C242T polymorphism and ischemic stroke in Japan: The Fukuoka Stroke Registry and the Hisayama study

Kuroda, J., Kitazono, T., Ago, T., Ninomiya, T., Ooboshi, H., Kamouchi, M., Kumai, Y., Hagiwara, N., Yoshimura, S., Tamaki, K., Kusuda, K., Fujii, K., Nagao, T., Okada, Y., Toyoda, K., Nakane, H., Sugimori, H., Yamashita, Y., Wakugawa, Y., Asano, K. & 4 others, Tanizaki, Y., Kiyohara, Y., Ibayashi, S. & Iida, M., Oct 1 2007, In : European Journal of Neurology. 14, 10, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

p40phox as an alternative organizer to p47phox in Nox2 activation: A new mechanism involving an interaction with p22phox

Tamura, M., Shiozaki, I., Ono, S., Miyano, K., Kunihiro, S. & Sasaki, T., Sep 18 2007, In : FEBS Letters. 581, 23, p. 4533-4538 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Peripheral tolerance and the qualitative characteristics of autoreactive T cell clones in primary biliary cirrhosis

Kawano, A., Shimoda, S., Kamihira, T., Ishikawa, F., Niiro, H., Soejima, Y., Taketomi, A., Maehara, Y., Nakamura, M., Komori, A., Migita, K., Ishibashi, H., Azuma, M., Gershwin, M. E. & Harada, M., Sep 1 2007, In : Journal of Immunology. 179, 5, p. 3315-3324 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Polymorphisms of cytochrome P450 1A1, glutathione S-transferase class mu, and tumour protein p53 genes and the risk of developing gallbladder cancer in Japanese

Tsuchiya, Y., Kiyohara, C., Sato, T., Nakamura, K., Kimura, A. & Yamamoto, M., Aug 1 2007, In : Clinical Biochemistry. 40, 12, p. 881-886 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Postischemic gene transfer of soluble Flt-1 protects against brain ischemia with marked attenuation of blood-brain barrier permeability

Kumai, Y., Ooboshi, H., Ibayashi, S., Ishikawa, E., Sugimori, H., Kamouchi, M., Kitazono, T., Egashira, K. & Iida, M., Jun 1 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 6, p. 1152-1160 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Prehypertension increases the risk for renal arteriosclerosis in autopsies: The Hisayama study

Ninomiya, T., Kubo, M., Doi, Y., Yonemoto, K., Tanizaki, Y., Tsuruya, K., Sueishi, K., Tsuneyoshi, M., Iida, M. & Kiyohara, Y., Jul 1 2007, In : Journal of the American Society of Nephrology. 18, 7, p. 2135-2142 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

Sadanaga, A., Nakashima, H., Akahoshi, M., Masutani, K., Miyake, K., Igawa, T., Sugiyama, N., Niiro, H. & Harada, M., May 1 2007, In : Arthritis and rheumatism. 56, 5, p. 1618-1628 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Role of NHE1 in calcium oscillation and cell proliferation in human CNS pericytes

Nakamura, K., Kamouchi, M., Kitazono, T., Kuroda, J., Matsuo, R., Hagiwara, N., Ooboshi, H., Ibayashi, S. & Iida, M., Nov 13 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1, p. BP41-01W

Research output: Contribution to journalArticle

Role of substantia innominata in cerebral blood flow autoregulation

Ota, K., Kitazono, T., Ooboshi, H., Kamouchi, M., Katafuchi, T., Aou, S., Yamashita, Y., Ibayashi, S. & Iida, M., Mar 2 2007, In : Brain Research. 1135, 1, p. 146-153 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Role of the small GTPase Rac in p22phox-dependent NADPH oxidases

Miyano, K. & Sumimoto, H., Sep 1 2007, In : Biochimie. 89, 9, p. 1133-1144 12 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Smoking and depression in diabetic patients

Iino, K., Iwase, M., Nohara, S., Fujii, H., Morimoto, S. & Iida, M., Dec 1 2007, In : Journal of the Japan Diabetes Society. 50, 11, p. 785-790 6 p.

Research output: Contribution to journalArticle

The coronal plane high tibial osteotomy. Part 1: A clinical and radiographic analysis of intermediate term outcomes

Baumgarten, K. M., Fealy, S., Lyman, S. & Wickiewicz, T. L., Sep 1 2007, In : HSS Journal. 3, 2, p. 147-154 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways

Ishikawa, F., Niiro, H., Iino, T., Yoshida, S., Saito, N., Onohara, S., Miyamoto, T., Minagawa, H., Fujii, S. I., Shultz, L. D., Harada, M. & Akashi, K., Nov 15 2007, In : Blood. 110, 10, p. 3591-3600 10 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

The Wnt/β-catenin signaling pathway as a target in drug discovery

Takahashi-Yanaga, F. & Sasaguri, T., Sep 13 2007, In : Journal of Pharmacological Sciences. 104, 4, p. 293-302 10 p.

Research output: Contribution to journalReview article

115 Citations (Scopus)

Validity and reproducibility of the PC-assisted dietary interview used in the Fukuoka colorectal cancer study

Uchida, K., Kimura, Y., Shirota, T. & Kono, S., Jan 1 2007, In : Asian Pacific Journal of Cancer Prevention. 8, 4, p. 583-590 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Wnt/beta-catenin signaling pathway and drug discovery

Takahashi-Yanaga, F. & Sasaguri, T., Apr 2007, In : Fukuoka igaku zasshi = Hukuoka acta medica. 98, 4, p. 93-99 7 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2006

A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: The Hisayama study

Shikata, K., Kiyohara, Y., Kubo, M., Yonemoto, K., Ninomiya, T., Shirota, T., Tanizaki, Y., Doi, Y., Tanaka, K., Oishi, Y., Matsumoto, T. & Iida, M., Jul 1 2006, In : International Journal of Cancer. 119, 1, p. 196-201 6 p.

Research output: Contribution to journalArticle

163 Citations (Scopus)

Association of genetic polymorphisms in the base excision repair pathway with lung cancer risk: A meta-analysis

Kiyohara, C., Takayama, K. & Nakanishi, Y., Dec 1 2006, In : Lung Cancer. 54, 3, p. 267-283 17 p.

Research output: Contribution to journalReview article

153 Citations (Scopus)

Autoreactive T-Cell Responses in Primary Biliary Cirrhosis Are Proinflammatory Whereas Those of Controls Are Regulatory

Shimoda, S., Ishikawa, F., Kamihira, T., Komori, A., Niiro, H., Baba, E., Harada, K., Isse, K., Nakanuma, Y., Ishibashi, H., Gershwin, M. E. & Harada, M., Jan 1 2006, In : Gastroenterology. 131, 2, p. 606-618 13 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Blood pressure changes during the initial week after different subtypes of ischemic stroke

Toyoda, K., Okada, Y., Fujimoto, S., Hagiwara, N., Nakachi, K., Kitazono, T., Ibayashi, S. & Iida, M., Oct 1 2006, In : Stroke. 37, 10, p. 2637-2639 3 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Clinical pharmacokinetic study of arsenic trioxide in an acute promyelocytic leukemia (APL) patient: Speciation of arsenic metabolites in serum and urine

Fukai, Y., Hirata, M., Ueno, M., Ichikawa, N., Kobayashi, H., Saitoh, H., Sakurai, T., Kinoshita, K., Kaise, T. & Ohta, S., May 1 2006, In : Biological and Pharmaceutical Bulletin. 29, 5, p. 1022-1027 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

C-reactive protein and risk of first-ever ischemic and hemorrhagic stroke in a general Japanese population: The Hisayama study

Wakugawa, Y., Kiyohara, Y., Tanizaki, Y., Kubo, M., Ninomiya, T., Hata, J., Doi, Y., Okubo, K., Oishi, Y., Shikata, K., Yonemoto, K., Maebuchi, D., Ibayashi, S. & Iida, M., Jan 1 2006, In : Stroke. 37, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Decreasing incidence of lacunar vs other types of cerebral infarction in a Japanese population

Kubo, M., Kiyohara, Y., Ninomiya, T., Tanizaki, Y., Yonemoto, K., Doi, Y., Hata, J., Oishi, Y., Shikata, K. & Iida, M., May 1 2006, In : Neurology. 66, 10, p. 1539-1544 6 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines

Matsuzaki, E., Takahashi-Yanaga, F., Miwa, Y., Hirata, M., Watanabe, Y., Sato, N., Morimoto, S., Hirofuji, T., Maeda, K. & Sasaguri, T., Aug 1 2006, In : Journal of Bone and Mineral Research. 21, 8, p. 1307-1316 10 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1

Miyano, K., Yamamoto, N., Takeya, R. & Sumimoto, H., Aug 4 2006, In : Journal of Biological Chemistry. 281, 31, p. 21857-21860 4 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Elevated cerebrospinal fluid lactate levels and the pathomechanism of calcification in Fahr's disease

Hagiwara, N., Ooboshi, H., Ishibashi, M., Kurushima, H., Kitazono, T., Ibayashi, S. & Iida, M., May 1 2006, In : European Journal of Neurology. 13, 5, p. 539-543 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

EPHX1 polymorphisms and the risk of lung cancer: A HuGE review

Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Jan 1 2006, In : Epidemiology. 17, 1, p. 89-99 11 p.

Research output: Contribution to journalReview article

68 Citations (Scopus)

Fasudil hydrochloride

Kitazono, T., Oct 28 2006, In : Nippon rinsho. Japanese journal of clinical medicine. 64 Suppl 7, p. 617-621 5 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Gender-related association of serum uric acid and left ventricular hypertrophy in hypertension

Matsumura, K., Ohtsubo, T., Oniki, H., Fujii, K. & Iida, M., Jul 7 2006, In : Circulation Journal. 70, 7, p. 885-888 4 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Involvement of GSK-3β and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells

Takahashi-Yanaga, F., Mori, J., Matsuzaki, E., Watanabe, Y., Hirata, M., Miwa, Y., Morimoto, S. & Sasaguri, T., Dec 15 2006, In : Journal of Biological Chemistry. 281, 50, p. 38489-38497 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Meta- and pooled analysis of GSTT1 and lung cancer: A HuGE-GSEC review

Raimondi, S., Paracchini, V., Autrup, H., Barros-Dios, J. M., Benhamou, S., Boffetta, P., Cote, M. L., Dialyna, I. A., Dolzan, V., Filiberti, R., Garte, S., Hirvonen, A., Husgafvel-Pursiainen, K., Imyanitov, E. N., Kalina, I., Kang, D., Kiyohara, C., Kohno, T., Kremers, P., Lan, Q. & 22 others, London, S., Povey, A. C., Rannug, A., Reszka, E., Risch, A., Romkes, M., Schneider, J., Seow, A., Shields, P. G., Sobti, R. C., Sørensen, M., Spinola, M., Spitz, M. R., Strange, R. C., Stücker, I., Sugimura, H., To-Figueras, J., Tokudome, S., Yang, P., Yuan, J. M., Warholm, M. & Taioli, E., Dec 1 2006, In : American journal of epidemiology. 164, 11, p. 1027-1042 16 p.

Research output: Contribution to journalReview article

113 Citations (Scopus)

Metabolic Syndrome and CKD in a General Japanese Population: The Hisayama Study

Ninomiya, T., Kiyohara, Y., Kubo, M., Yonemoto, K., Tanizaki, Y., Doi, Y., Hirakata, H. & Iida, M., Sep 1 2006, In : American Journal of Kidney Diseases. 48, 3, p. 383-391 9 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

Prediction of cognitive function by arterial stiffness in the very elderly

Fukuhara, M., Matsumura, K., Ansai, T., Takata, Y., Sonoki, K., Akifusa, S., Wakisaka, M., Hamasaki, T., Fujisawa, K., Yoshida, A., Fujii, K., Iida, M. & Takehara, T., Jun 5 2006, In : Circulation Journal. 70, 6, p. 756-761 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Risk of postpartum depression in relation to dietary fish and fat intake in Japan: The Osaka Maternal and Child Health Study

Miyake, Y., Sasaki, S., Yokoyama, T., Tanaka, K., Ohya, Y., Fukushima, W., Saito, K., Ohfuji, S., Kiyohara, C., Hirota, Y., Matsunaga, I., Oda, H., Kanzaki, H., Kitada, M., Horikoshi, Y., Ishiko, O., Nakai, Y., Nishio, J., Yamamasu, S., Yasuda, J. & 16 others, Kawai, S., Yanagihara, K., Wakuda, K., Kawashima, T., Narimoto, K., Iwasa, Y., Orino, K., Tsunetoh, I., Yoshida, J., Junichi, I., Kaneko, T., Kamiya, T., Kuribayashi, H., Taniguchi, T., Takemura, H. & Morimoto, Y., Dec 1 2006, In : Psychological Medicine. 36, 12, p. 1727-1735 9 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Role of aldosterone in left ventricular hypertrophy in hypertension

Matsumura, K., Fujii, K., Oniki, H., Oka, M. & Iida, M., Jan 1 2006, In : American Journal of Hypertension. 19, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Sleep disorders and suicidal ideation in Japanese patients visiting a psychosomatic clinic in a university hospital

Yoshimasu, K., Sugahara, H., Akamine, M., Kondo, T., Fujisawa, K., Tokunaga, S., Kiyohara, C., Miyashita, K. & Kubo, C., Jun 1 2006, In : Sleep and Biological Rhythms. 4, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: Findings from the KYSS study

Washio, M., Horiuchi, T., Kiyohara, C., Kodama, H., Tada, Y., Asami, T., Takahashi, H., Kobashi, G., Abe, T., Tanaka, H., Nogami, N., Harada, M., Tsukamoto, H., Ide, S., Nagasawa, K., Ushiyama, O., Hotokebuchi, T., Okamoto, K., Sakamoto, N., Sasaki, S. & 9 others, Miyake, Y., Yokoyama, T., Mori, M., Oura, A., Sinomura, Y., Suzuki, H., Yamamoto, M., Inaba, Y. & Nagai, M., Mar 1 2006, In : Modern Rheumatology. 16, 3, p. 143-150 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

The serum pepsinogen test as a predictor of gastric cancer: The Hisayama study

Oishi, Y., Kiyohara, Y., Kubo, M., Tanaka, K., Tanizaki, Y., Ninomiya, T., Doi, Y., Shikata, K., Yonemoto, K., Shirota, T., Matsumoto, T. & Iida, M., Apr 1 2006, In : American journal of epidemiology. 163, 7, p. 629-637 9 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Transoral ultrasonographic evaluation of carotid flow in predicting cerebral hemodynamics after carotid endarterectomy

Kamouchi, M., Kishikawa, K., Okada, Y., Inoue, T., Toyoda, K., Ibayashi, S. & Iida, M., Jun 1 2006, In : American Journal of Neuroradiology. 27, 6, p. 1295-1299 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Valsartan improves the lower limit of cerebral autoregulation in rats

Takada, J., Ibayashi, S., Ooboshi, H., Ago, T., Ishikawa, E., Kamouchi, M., Kitazono, T. & Iida, M., Aug 1 2006, In : Hypertension Research. 29, 8, p. 621-626 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Venous infarction secondary to septic cavernous sinus thrombosis

Kamouchi, M., Wakugawa, Y., Okada, Y., Kishikawa, K., Matsuo, R., Toyoda, K., Yasumori, K., Inoue, T., Ibayashi, S. & Iida, M., Feb 1 2006, In : Internal Medicine. 45, 1, p. 25-27 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2005

[Fragments of information of Naoe Okamoto - the life of one of Japan's first female pharmacists.].

Takahashi, F. & Kobayashi, K., Dec 1 2005, In : Yakushigaku zasshi. The Journal of Japanese history of pharmacy. 40, 1, p. 52-61 10 p.

Research output: Contribution to journalArticle

A case of recanalized cardioembolic stroke: Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy

Ogata, T., Kitazono, T., Kuroda, J., Kamei, K., Kamouchi, M., Ooboshi, H., Ibayashi, S. & Iida, M., Apr 2005, In : Journal of Ultrasound in Medicine. 24, 4, p. 561-565 5 p.

Research output: Contribution to journalArticle

Activator protein-1 mediates shear stress-induced prostaglandin D synthase gene expression in vascular endothelial cells

Miyagi, M., Miwa, Y., Takahashi-Yanaga, F., Morimoto, S. & Sasaguri, T., May 1 2005, In : Arteriosclerosis, thrombosis, and vascular biology. 25, 5, p. 970-975 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Amelioration of autoimmune nephritis by imatinib in MRL/lpr mice

Sadanaga, A., Nakashima, H., Masutani, K., Miyake, K., Shimizu, S., Igawa, T., Sugiyama, N., Niiro, H., Hirakata, H. & Harada, M., Dec 1 2005, In : Arthritis and rheumatism. 52, 12, p. 3987-3996 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

A new type of O2--generating tool for oxidative stress studies by remodeling neutrophil NADPH oxidase

Tamura, M., Nagasawa, T., Tange, T., Miyano, K., Kobayashi, S. I., Nakai, T. & Miura, S., Dec 6 2005, In : Journal of Biotechnology. 120, 4, p. 421-429 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Blood pressure control in hypertensive patients with a history of stroke

Ohta, Y., Tsuchihashi, T., Ibayashi, S., Matsumura, K., Kitazono, T., Ooboshi, H., Kamouchi, M., Fujii, K. & Iida, M., Nov 1 2005, In : Journal of Stroke and Cerebrovascular Diseases. 14, 6, p. 229-233 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Central and peripheral cardiovascular actions of apelin in conscious rats

Kagiyama, S., Fukuhara, M., Matsumura, K., Lin, Y., Fujii, K. & Iida, M., Feb 15 2005, In : Regulatory Peptides. 125, 1-3, p. 55-59 5 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)