Department of Medical Education

Research Output 1983 2020

2016
31 Citations (Scopus)

Three-month risk-benefit profile of anticoagulation after stroke with atrial fibrillation: The SAMURAI-Nonvalvular Atrial Fibrillation (NVAF) study

Arihiro, S., Todo, K., Koga, M., Furui, E., Kinoshita, N., Kimura, K., Yamagami, H., Terasaki, T., Yoshimura, S., Shiokawa, Y., Kamiyama, K., Takizawa, S., Okuda, S., Okada, Y., Nagakane, Y., Kameda, T., Hasegawa, Y., Shibuya, S., Ito, Y., Nakashima, T. & 10 others, Takamatsu, K., Nishiyama, K., Matsuki, T., Homma, K., Takasugi, J., Tokunaga, K., Sato, S., Kario, K., Kitazono, T. & Toyoda, K., Jan 1 2016, In : International Journal of Stroke. 11, 5, p. 565-574 10 p.

Research output: Contribution to journalArticle

Anticoagulants
Atrial Fibrillation
Stroke
Transient Ischemic Attack
Warfarin
1470 Citations (Scopus)

Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants

NCD Risk Factor Collaboration (NCD-RisC), Apr 2 2016, In : The Lancet. 387, 10026, p. 1377-1396 20 p.

Research output: Contribution to journalArticle

Body Mass Index
Morbid Obesity
Thinness
Population
Obesity
15 Citations (Scopus)

Trends in autopsy-verified dementia prevalence over 29 years of the Hisayama study

Honda, H., Sasaki, K., Hamasaki, H., Shijo, M., Koyama, S., Ohara, T., Ninomiya, T., Kiyohara, Y., Suzuki, S. O. & Iwaki, T., Aug 1 2016, In : Neuropathology. 36, 4, p. 383-387 5 p.

Research output: Contribution to journalArticle

Dementia
Autopsy
Alzheimer Disease
Pathology
Life Style
7 Citations (Scopus)

Trends in blood pressure control and medication use during 20 years in a hypertension clinic in Japan

Kansui, Y., Ibaraki, A., Goto, K., Haga, Y., Seki, T., Takiguchi, T., Ohtsubo, T., Kitazono, T. & Matsumura, K., Apr 2 2016, In : Clinical and Experimental Hypertension. 38, 3, p. 299-304 6 p.

Research output: Contribution to journalArticle

Japan
Blood Pressure
Hypertension
Antihypertensive Agents
Guidelines
20 Citations (Scopus)

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis

Numaga-Tomita, T., Kitajima, N., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., Dec 19 2016, In : Scientific reports. 6, 39383.

Research output: Contribution to journalArticle

Cardiac Myocytes
Fibrosis
Microtubules
Pressure
Fibroblasts
33 Citations (Scopus)

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Kitajima, N., Numaga-Tomita, T., Watanabe, M., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., Nov 11 2016, In : Scientific reports. 6, 37001.

Research output: Contribution to journalArticle

NADPH Oxidase
Reactive Oxygen Species
Physiological Adaptation
Proteasome Endopeptidase Complex
Cardiac Myocytes
116 Citations (Scopus)

Type 2diabetes as a risk factor for dementia in women compared with men: A pooled analysis of 2.3 million people comprising more than 100,000 cases of dementia

Chatterjee, S., Peters, S. A. E., Woodward, M., Arango, S. M., Batty, G. D., Beckett, N., Beiser, A., Borenstein, A. R., Crane, P. K., Haan, M., Hassing, L. B., Hayden, K. M., Kiyohara, Y., Larson, E. B., Li, C. Y., Ninomiya, T., Ohara, T., Peters, R., Russ, T. C., Seshadri, S. & 4 others, Strand, B. H., Walker, R., Xu, W. & Huxley, R. R., Feb 2016, In : Diabetes care. 39, 2, p. 300-307 8 p.

Research output: Contribution to journalArticle

Dementia
Vascular Dementia
Type 2 Diabetes Mellitus
Meta-Analysis
Research Design
33 Citations (Scopus)
Arthroscopy
Arthroplasty
Hip
Population
Obesity
5 Citations (Scopus)

Very low protein diet enhances inflammation, malnutrition, and vascular calcification in uremic rats

Yamada, S., Tokumoto, M., Tatsumoto, N., Tsuruya, K., Kitazono, T. & Ooboshi, H., Feb 1 2016, In : Life Sciences. 146, p. 117-123 7 p.

Research output: Contribution to journalArticle

Vascular Calcification
Protein-Restricted Diet
Nutrition
Malnutrition
Rats
586 Citations (Scopus)

Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants

NCD Risk Factor Collaboration (NCD-RisC), Apr 9 2016, In : The Lancet. 387, 10027

Research output: Contribution to journalArticle

Population
Micronesia
Polynesia
Population Growth
American Samoa
2017
1 Citation (Scopus)

A case of cardioembolic stroke due to intracardiac papillary fibroelastoma evaluated by using transesophageal echocardiography

Ohya, Y., Fujimoto, S., Kanazawa, M., Tagawa, N., Osaki, M. & Kitazono, T., Jan 1 2017, In : Clinical Neurology. 57, 1, p. 9-13 5 p.

Research output: Contribution to journalArticle

Transesophageal Echocardiography
Stroke
Intracranial Embolism
Dysarthria
Paresthesia
3 Citations (Scopus)

A Case of Recurrent Ischemic Stroke due to Intravascular Lymphomatosis, Undiagnosed by Random Skin Biopsy and Brain Imaging

Ohya, Y., Osaki, M., Sakai, S., Kimura, S., Shimogamo, T., Ago, T., Kitazono, T. & Arakawa, S., Jan 1 2017, In : Case Reports in Neurology. 9, 3, p. 234-240 7 p.

Research output: Contribution to journalArticle

Neuroimaging
Lymphoma
Stroke
Biopsy
Skin
Type 1 Diabetes Mellitus
leflunomide
Insulin
Rheumatoid Arthritis
Pharmaceutical Preparations
1 Citation (Scopus)

A Crosswalk Between UCLA and Lower Extremity Activity Scales

Ghomrawi, H. M. K., Lee, Y. Y., Herrero, C., Joseph, A., Padgett, D., Westrich, G., Parks, M. & Lyman, S., Feb 1 2017, In : Clinical orthopaedics and related research. 475, 2, p. 542-548 7 p.

Research output: Contribution to journalArticle

Los Angeles
Lower Extremity
Tacrine
Activities of Daily Living
ROC Curve
4 Citations (Scopus)
Dementia
Registries
Stroke
Propensity Score
Logistic Models
10 Citations (Scopus)

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN)

the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Jan 1 2017, In : Journal of epidemiology. 27, 3, p. 123-129 7 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Japan
Cardiovascular Diseases
Mortality
Research
6 Citations (Scopus)

A J-shaped association between serum uric acid levels and poor renal survival in female patients with IgA nephropathy

Matsukuma, Y., Masutani, K., Tanaka, S., Tsuchimoto, A., Fujisaki, K., Torisu, K., Katafuchi, R., Hirakata, H., Tsuruya, K. & Kitazono, T., Mar 1 2017, In : Hypertension Research. 40, 3, p. 291-297 7 p.

Research output: Contribution to journalArticle

Uric Acid
Immunoglobulin A
Kidney
IGA Glomerulonephritis
Chronic Kidney Failure
18 Citations (Scopus)

All-cause versus complication-specific readmission following total knee arthroplasty

D'Apuzzo, M., Westrich, G., Hidaka, C., Pan, T. J. & Lyman, S., Jan 1 2017, In : Journal of Bone and Joint Surgery - American Volume. 99, 13, p. 1093-1103 11 p.

Research output: Contribution to journalArticle

Knee Replacement Arthroplasties
Odds Ratio
Confidence Intervals
Patient Readmission
Medicaid
4 Citations (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
13 Citations (Scopus)

Angiotensin II receptor-neprilysin inhibitor sacubitril/valsartan improves endothelial dysfunction in spontaneously hypertensive rats

Seki, T., Goto, K., Kansui, Y., Ohtsubo, T., Matsumura, K. & Kitazono, T., Oct 1 2017, In : Journal of the American Heart Association. 6, 10, e006617.

Research output: Contribution to journalArticle

Valsartan
Neprilysin
Angiotensin Receptors
Inbred SHR Rats
Endothelium
5 Citations (Scopus)

Arthroplasty treatment of proximal humerus fractures: 14-year trends in the United States

Schairer, W. W., Nwachukwu, B. U., Lyman, S. & Gulotta, L. V., Apr 3 2017, In : Physician and Sportsmedicine. 45, 2, p. 92-96 5 p.

Research output: Contribution to journalArticle

Humerus
Arthroplasty
Therapeutics
Hemiarthroplasty
International Classification of Diseases
6 Citations (Scopus)
Genetic Polymorphisms
Lung Neoplasms
Japan
Vascular Endothelial Growth Factor A
Smoking
7 Citations (Scopus)

Association between onset-to-door time and clinical outcomes after ischemic stroke

Matsuo, R., Yamaguchi, Y., Matsushita, T., Hata, J., Kiyuna, F., Fukuda, K., Wakisaka, Y., Kuroda, J., Ago, T., Kitazono, T., Kamouchi, M., Ishitsuka, T., Ibayashi, S., Kusuda, K., Fujii, K., Nagao, T., Okada, Y., Yasaka, M., Ooboshi, H., Irie, K. & 9 others, Omae, T., Toyoda, K., Nakane, H., Sugimori, H., Arakawa, S., Kitayama, J., Fujimoto, S., Arihiro, S. & Fukushima, Y., Nov 2017, In : Stroke. 48, 11, p. 3049-3056 8 p.

Research output: Contribution to journalArticle

Stroke
Reperfusion
National Institutes of Health (U.S.)
Therapeutics
Japan
2 Citations (Scopus)

Association between responsiveness to methoxy polyethylene glycol-epoetin beta and renal survival in patients with non-dialysis-dependent chronic kidney disease: A pooled analysis of individual patient-level data from clinical trials

Tsuruya, K., Uemura, Y., Hirakata, H., Kitazono, T., Tsubakihara, Y., Suzuki, M. & Ohashi, Y., Oct 2017, In : Nephrology. 22, 10, p. 769-775 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Clinical Trials
Kidney
Hematinics
Survival Rate
1 Citation (Scopus)

Association between serum uric acid level and renal arteriolar hyalinization in individuals without chronic kidney disease

Matsukuma, Y., Masutani, K., Tanaka, S., Tsuchimoto, A., Haruyama, N., Okabe, Y., Nakamura, M., Tsuruya, K. & Kitazono, T., Nov 2017, In : Atherosclerosis. 266, p. 121-127 7 p.

Research output: Contribution to journalArticle

Uric Acid
Chronic Renal Insufficiency
Kidney
Serum
Living Donors
6 Citations (Scopus)
Vitamin D
Cause of Death
Respiratory Tract Infections
Cardiovascular Infections
Serum
1 Citation (Scopus)

Association between the maximal distance of atrial septal protrusion and cryptogenic stroke

Tokunaga, K., Yasaka, M., Kuwashiro, T., Gotoh, S., Nakamura, A., Takaguchi, G., Ago, T., Kamouchi, M., Kitazono, T. & Okada, Y., Jan 1 2017, In : International Journal of Stroke. 12, 9, p. 941-945 5 p.

Research output: Contribution to journalArticle

Stroke
Aneurysm
Intracranial Embolism
Heart Atria
Odds Ratio
2 Citations (Scopus)

Association of airflow limitation with carotid atherosclerosis in a japanese community ― the hisayama study

Kudo, K., Hata, J., Matsumoto, K., Shundo, Y., Fukuyama, S., Inoue, H., Kitazono, T., Kiyohara, Y., Ninomiya, T. & Nakanishi, Y., Jan 1 2017, In : Circulation Journal. 81, 12, p. 1846-1853 8 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Population
Independent Living
Carotid Intima-Media Thickness
Spirometry
3 Citations (Scopus)

Association of Hypertriglyceridemia With the Incidence and Progression of Chronic Kidney Disease and Modification of the Association by Daily Alcohol Consumption

Tsuruya, K., Yoshida, H., Nagata, M., Kitazono, T., Iseki, K., Iseki, C., Fujimoto, S., Konta, T., Moriyama, T., Yamagata, K., Narita, I., Kimura, K., Kondo, M., Asahi, K., Ohashi, Y. & Watanabe, T., Nov 2017, In : Journal of Renal Nutrition. 27, 6, p. 381-394 14 p.

Research output: Contribution to journalArticle

Hypertriglyceridemia
Chronic Renal Insufficiency
Alcohol Drinking
Triglycerides
Incidence
10 Citations (Scopus)

Associations with health-related quality of life after intracerebral haemorrhage: Pooled analysis of INTERACT studies

Delcourt, C., Zheng, D., Chen, X., Hackett, M., Arima, H., Hata, J., Heeley, E., Al-Shahi Salman, R., Woodward, M., Huang, Y., Robinson, T., Lavados, P. M., Lindley, R. I., Stapf, C., Davies, L., Chalmers, J., Anderson, C. S. & Sato, S., Jan 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 1, p. 70-75 6 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Quality of Life
National Institutes of Health (U.S.)
Proxy
Stroke

Asymptomatic Brain Edema after Hemodialysis Initiation in a Patient with Severe Uremia

Fujisaki, K., Nakagawa, K., Nagae, H., Nakano, T., Taniguchi, M., Masutani, K., Kitazono, T. & Tsuruya, K., Jan 1 2017, In : Case Reports in Medicine. 2017, 9265315.

Research output: Contribution to journalArticle

Uremia
Brain Edema
Renal Dialysis
Dialysis
Magnetic Resonance Imaging

Author response: Trends in dementia prevalence, incidence, and survival rate in a Japanese community

Ohara, T. & Ninomiya, T., Oct 31 2017, In : Neurology. 89, 18, p. 1930-1931 2 p.

Research output: Contribution to journalComment/debate

Dementia
Survival Rate
Incidence
6 Citations (Scopus)

Autophagy promotes degradation of internalized collagen and regulates distribution of focal adhesions to suppress cell adhesion

Kawano, S., Torisu, T., Esaki, M., Torisu, K., Matsuno, Y. & Kitazono, T., Nov 15 2017, In : Biology Open. 6, 11, p. 1644-1653 10 p.

Research output: Contribution to journalArticle

Focal Adhesions
autophagy
Cell adhesion
Autophagy
cell adhesion
1 Citation (Scopus)
Genetic Polymorphisms
Case-Control Studies
Lung Neoplasms
Japan
Smoking
6 Citations (Scopus)

Blood pressure control status and relationship between salt intake and lifestyle including diet in hypertensive outpatients treated at a general hospital

Ohta, Y., Kimura, Y., Kitaoka, C., Sakata, T., Abe, I. & Kawano, Y., Jan 2 2017, In : Clinical and Experimental Hypertension. 39, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

General Hospitals
Life Style
Outpatients
Salts
Diet

Bone Morphogenetic Proteins in Pediatric Spinal Arthrodesis: A Statewide Analysis of Trends and Outcome of Utilization

Nwachukwu, B. U., Schairer, W. W., Pan, T., Widmann, R. F., Blanco, J. S., Green, D. W., Lyman, S. & Dodwell, E. R., Jan 1 2017, In : Journal of Pediatric Orthopaedics. 37, 6, p. e369-e374

Research output: Contribution to journalArticle

Bone Morphogenetic Proteins
Arthrodesis
Pediatrics
Off-Label Use
Spondylolisthesis
71 Citations (Scopus)

Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease An Individual Participant Data Meta-Analysis

Ohkuma, T., Ninomiya, T., Tomiyama, H., Kario, K., Hoshide, S., Kita, Y., Inoguchi, T., Maeda, Y., Kohara, K., Tabara, Y., Nakamura, M., Ohkubo, T., Watada, H., Munakata, M., Ohishi, M., Ito, N., Nakamura, M., Shoji, T., Vlachopoulos, C. & Yamashina, A., Jun 1 2017, In : Hypertension. 69, 6, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Pulse Wave Analysis
Ankle
Meta-Analysis
Arm
Cardiovascular Diseases
10 Citations (Scopus)

Cardiothoracic Ratio and All-Cause Mortality and Cardiovascular Disease Events in Hemodialysis Patients: The Q-Cohort Study

Yotsueda, R., Taniguchi, M., Tanaka, S., Eriguchi, M., Fujisaki, K., Torisu, K., Masutani, K., Hirakata, H., Kitazono, T. & Tsuruya, K., Jul 2017, In : American Journal of Kidney Diseases. 70, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

Renal Dialysis
Cohort Studies
Cardiovascular Diseases
Mortality
Blood Pressure
14 Citations (Scopus)

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway

Egashira, I., Takahashi-Yanaga, F., Nishida, R., Arioka, M., Igawa, K., Tomooka, K., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Kitazono, T. & Sasaguri, T., Jan 1 2017, In : Cancer Science. 108, 1, p. 108-115 8 p.

Research output: Contribution to journalArticle

Celecoxib
Intestinal Neoplasms
Catenins
Wnt Signaling Pathway
Growth

Changes to Hospital Inpatient Volume After Newspaper Reporting of Medical Errors

Fukuda, H., Jun 30 2017, (Accepted/In press) In : Journal of Patient Safety.

Research output: Contribution to journalArticle

Medical Errors
Newspapers
Inpatients
Case-Control Studies
Motivation
14 Citations (Scopus)

Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, 3, p. S36-S42

Research output: Contribution to journalArticle

Colorectal Neoplasms
Japan
Rectal Neoplasms
Colonic Neoplasms
Life Style
9 Citations (Scopus)

Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, 3, p. S58-S64

Research output: Contribution to journalArticle

Japan
Breast Neoplasms
Carcinoma
Estrogen Receptors
Mortality
1 Citation (Scopus)

Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, p. S98-S106

Research output: Contribution to journalArticle

Japan
Breast Neoplasms
Carcinoma
Estrogen Receptors
Mortality
7 Citations (Scopus)

Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, 3, p. S49-S57

Research output: Contribution to journalArticle

Lung Neoplasms
Japan
Small Cell Carcinoma
Mortality
Life Style
5 Citations (Scopus)

Characteristics of orthopedic publications in high-impact general medical journals

Nwachukwu, B. U., Kahlenberg, C. A., Lehman, J. D., Lyman, S. & Marx, R. G., May 1 2017, In : Orthopedics. 40, 3, p. e405-e412

Research output: Contribution to journalReview article

Orthopedics
Publications
Health Policy
Delivery of Health Care
5 Citations (Scopus)

Characteristics of patients with liver cancer in the BioBank Japan project

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, 3, p. S43-S48

Research output: Contribution to journalArticle

Liver Neoplasms
Japan
Hepacivirus
Hepatocellular Carcinoma
Histology
8 Citations (Scopus)

Characteristics of primary and metachronous gastric cancers discovered after helicobacter pylori eradication: A multicenter propensity score-matched study

Maehata, Y., Nakamura, S., Esaki, M., Ikeda, F., Moriyama, T., Hida, R., Washio, E., Umeno, J., Hirahashi, M., Kitazono, T. & Matsumoto, T., Sep 2017, In : Gut and Liver. 11, 5, p. 628-634 7 p.

Research output: Contribution to journalArticle

Propensity Score
Helicobacter pylori
Stomach Neoplasms
Neoplasms
Helicobacter Infections
1 Citation (Scopus)

Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan

Biobank Japan Cooperative Hospital Group, Jan 1 2017, In : Journal of epidemiology. 27, 3, p. S77-S83

Research output: Contribution to journalArticle

Comorbidity
Japan
Cholesterol
Dyslipidemias
Serum
1 Citation (Scopus)

Chronic kidney disease in Asia: Protocol for a collaborative overview

Liyanage, T., Ninomiya, T., Perkovic, V., Woodward, M., Stirnadel-Farrant, H., Matsushita, K., Iseki, K., Seong, H. L., Monaghan, H. & Jha, V., Jun 2017, In : Nephrology. 22, 6, p. 456-462 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Longitudinal Studies
Kidney
Preventive Medicine
Information Storage and Retrieval
1 Citation (Scopus)

Circulating ferritin concentrations are differentially associated with serum adipokine concentrations in Japanese men and premenopausal women

Kimura, Y., Yasuda, K., Kurotani, K., Akter, S., Kashino, I., Hayabuchi, H., Sato, M. & Mizoue, T., Dec 1 2017, In : European Journal of Nutrition. 56, 8, p. 2497-2505 9 p.

Research output: Contribution to journalArticle

Adipokines
Ferritins
Nicotinamide Phosphoribosyltransferase
Leptin
Serum