Department of Medical Education

Research Output 1983 2020

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2010
69 Citations (Scopus)

Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies

Thompson, S., Kaptoge, S., White, I., Wood, A., Perry, P., Danesh, J., The Emerging Risk Factors Collaboration, E. R. F. C., Thompson, S. G., Kaptoge, S., White, I. R., Wood, A. M., Perry, P. L., Tipping, R. W., Ford, C. E., Simpson, L. M., Walldius, G., Jungner, I., Chambless, L. E., Panagiotakos, D. B., Pitsavos, C. & 225 others, Chrysohoou, C., Stefanadis, C., Knuiman, M., Goldbourt, U., Benderly, M., Tanne, D., Whincup, P. H., Wannamethee, S. G., Morris, R. W., Willeit, J., Kiechl, S., Santer, P., Mayr, A., Lawlor, D. A., Yarnell, J. W. G., Gallacher, J., Casiglia, E., Tikhonoff, V., Nietert, P. J., Sutherland, S. E., Bachman, D. L., Keil, J. E., Cushman, M., Tracy, R. P., Tybjærg-Hansen, A., Nordestgaard, B. G., Benn, M., Frikke- Schmidt, R., Giampaoli, S., Palmieri, L., Panico, S., Vanuzzo, D., Gómez de la Cámara, A., Gómez- Gerique, J. A., Simons, L., McCallum, J., Friedlander, Y., Fowkes, F. G. R., Lee, A. J., Taylor, J., Guralnik, J. M., Wallace, R., Guralnik, J., Blazer, D. G., Guralnik, J. M., Guralnik, J. M., Khaw, K. T., Brenner, H., Raum, E., Müller, H., Rothenbacher, D., Jansson, J. H., Wennberg, P., Nissinen, A., Donfrancesco, C., Salomaa, V., Harald, K., Jousilahti, P., Vartiainen, E., Woodward, M., D'Agostino, R. B., Vasan, R. S., Pencina, M. J., Bladbjerg, E. M., Jørgensen, T., Jespersen, J., Møller, L., Dankner, R., Chetrit, A., Lubin, F., Rosengren, A., Lappas, G., Björkelund, C., Lissner, L., Bengtsson, C., Cremer, P., Nagel, D., Tilvis, R. S., Strandberg, T. E., Kiyohara, Y., Arima, H., Doi, Y., Ninomiya, T., Rodriguez, B., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Rimm, E., Pai, J. K., Sato, S., Kitamura, A., Iso, H., Goldbourt, U., Salomaa, V., Noda, H., Harald, K., Jousilahti, P., Vartiainen, E., Salonen, J. T., Tuomainen, T. P., Deeg, D. J. H., Poppelaars, J. L., Meade, T. W., Cooper, J. A., Hedblad, B., Berglund, G., Engstrom, G., Verschuren, W. M. M., Blokstra, A., Cushman, M., Shea, S., Döring, A., Koenig, W., Meisinger, C., Mraz, W., Bas Bueno-de-Mesquita, H., Kuller, L. H., Grandits, G., Selmer, R., Tverdal, A., Nystad, W., Gillum, R., Mussolino, M., Rimm, E., Manson, J. E., Pai, J. K., Meade, T. W., Cooper, J. A., Cooper, J. A., Knottenbelt, C., Bauer, K. A., Naito, Y., Holme, I., Hankinson, S., Tverdal, A., Nystad, W., Nakagawa, H., Miura, K., Ducimetiere, P., Jouven, X., Crespo, C. J., Garcia Palmieri, M. R., Amouyel, P., Arveiler, D., Evans, A., Ferrieres, J., Schulte, H., Assmann, G., Shepherd, J., Packard, C. J., Sattar, N., Ford, I., Cantin, B., Després, J. P., Dagenais, G. R., Barrett-Connor, E., Wingard, D. L., Bettencourt, R., Gudnason, V., Aspelund, T., Sigurdsson, G., Thorsson, B., Trevisan, M., Witteman, J., Kardys, I., Breteler, M., Hofman, A., Tunstall-Pedoe, H., Tavendale, R., Lowe, G. D. O., Ben-Shlomo, Y., Howard, B. V., Zhang, Y., Umans, J., Onat, A., Davey-Smith, G., Wilsgaard, T., Ingelsson, E., Lind, L., Giedraitis, V., Lannfelt, L., Gaziano, J. M., Ridker, P., Gaziano, J. M., Ridker, P., Ulmer, H., Diem, G., Concin, H., Tosetto, A., Rodeghiero, F., Wassertheil-Smoller, S., Manson, J. E., Marmot, M., Clarke, R., Collins, R., Brunner, E., Shipley, M., Ridker, P., Buring, J., Shepherd, J., Cobbe, S. M., Ford, I., Robertson, M., He, Y., Marín Ibañez, A., Feskens, E. J. M., Kromhout, D., Collins, R., Di Angelantonio, E., Erqou, S., Kaptoge, S., Lewington, S., Orfei, L., Pennells, L., Perry, P. L., Ray, K. K., Sarwar, N., Alexander, M., Thompson, A., Thompson, S. G., Walker, M., Watson, S., Wensley, F., White, I. R. & Wood, A. M., Jan 1 2010, In : International Journal of Epidemiology. 39, 5, p. 1345-1359 15 p.

Research output: Contribution to journalArticle

Epidemiologic Studies
Meta-Analysis
Prospective Studies
Proportional Hazards Models
Fibrinogen
15 Citations (Scopus)

The effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population

Hata, J., Doi, Y., Ninomiya, T., Tanizaki, Y., Yonemoto, K., Fukuhara, M., Kubo, M., Kitazono, T., Iida, M. & Kiyohara, Y., May 1 2010, In : Atherosclerosis. 210, 1, p. 249-255 7 p.

Research output: Contribution to journalArticle

Stroke
Population
Waist Circumference
Confidence Intervals
Infarction
48 Citations (Scopus)

The NADPH oxidase Nox4 and aging in the heart

Ago, T., Matsushima, S., Kuroda, J., Zablocki, D., Kitazono, T. & Sadoshima, J., Dec 2010, In : Aging. 2, 12, p. 1012-1016 5 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Oxidative Stress
Mitochondria
Cardiac Myocytes
Intracellular Membranes
84 Citations (Scopus)

Trends in prevalence of Alzheimer's disease and vascular dementia in a Japanese community: The Hisayama Study

Sekita, A., Ninomiya, T., Tanizaki, Y., Doi, Y., Hata, J., Yonemoto, K., Arima, H., Sasaki, K., Iida, M., Iwaki, T., Kanba, S. & Kiyohara, Y., Oct 1 2010, In : Acta Psychiatrica Scandinavica. 122, 4, p. 319-325 7 p.

Research output: Contribution to journalArticle

Vascular Dementia
Alzheimer Disease
Dementia
Population
67 Citations (Scopus)

Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population: The Hisayama study

Nagata, M., Ninomiya, T., Doi, Y., Yonemoto, K., Kubo, M., Hata, J., Tsuruya, K., Iida, M. & Kiyohara, Y., Aug 2010, In : Nephrology Dialysis Transplantation. 25, 8, p. 2557-2564 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Confidence Intervals
Population
Glomerular Filtration Rate
Hypercholesterolemia
24 Citations (Scopus)

Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy

Wang, Y. Y., Morimoto, S., Du, C. K., Lu, Q. W., Zhan, D. Y., Tsutsumi, T., Ide, T., Miwa, Y., Takahashi-Yanaga, F. & Sasaguri, T., Sep 1 2010, In : Cardiovascular research. 87, 4, p. 636-646 11 p.

Research output: Contribution to journalArticle

Iodide Peroxidase
Dilated Cardiomyopathy
Up-Regulation
Thyroid Hormones
Propylthiouracil
10 Citations (Scopus)

Wegener's granulomatosis detected initially by integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography

Ueda, N., Inoue, Y., Himeji, D., Shimao, Y., Oryoji, K., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Ueda, A. & Akashi, K., Apr 1 2010, In : Modern Rheumatology. 20, 2, p. 205-209 5 p.

Research output: Contribution to journalArticle

Granulomatosis with Polyangiitis
Fluorodeoxyglucose F18
Early Diagnosis
Mucous Membrane
Biopsy
2009

A case of glucagonoma with skin lesions, anemia, and hypoaminoacidemia markedly improved by medical therapy

Ohkuma, T., Iwase, M., Idewaki, Y., Kikuchi, Y., Fujii, H., Oku, M., Morimoto, S., Doi, Y., Nakamura, U. & Iida, M., Dec 1 2009, In : Journal of the Japan Diabetes Society. 52, 12, p. 949-955 7 p.

Research output: Contribution to journalArticle

Glucagonoma
Necrolytic Migratory Erythema
Testosterone Congeners
Anemia
Hypoalbuminemia
30 Citations (Scopus)

Acute blood pressure levels and neurological deterioration in different subtypes of ischemic stroke

Toyoda, K., Fujimoto, S., Kamouchi, M., Iida, M. & Okada, Y., Jul 1 2009, In : Stroke. 40, 7, p. 2585-2588 4 p.

Research output: Contribution to journalArticle

Stroke
Blood Pressure
National Institutes of Health (U.S.)
Blood Glucose
Hospitalization
15 Citations (Scopus)

ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children

Matsusue, A., Kiyohara, C., Tanaka, K., Sasaki, S. & Miyake, Y., Apr 1 2009, In : Clinical Biochemistry. 42, 6, p. 477-483 7 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Atopic Dermatitis
Polymorphism
Haplotypes
Single Nucleotide Polymorphism
534 Citations (Scopus)

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes

Ninomiya, T., Perkovic, V., De Galan, B. E., Zoungas, S., Pillai, A., Jardine, M., Patel, A., Cass, A., Neal, B., Poulter, N., Mogensen, C. E., Cooper, M., Marre, M., Williams, B., Hamet, P., Mancia, G., Woodward, M., MacMahon, S. & Chalmers, J., Aug 1 2009, In : Journal of the American Society of Nephrology. 20, 8, p. 1813-1821 9 p.

Research output: Contribution to journalArticle

Albuminuria
Albumins
Creatinine
Kidney
Type 2 Diabetes Mellitus
13 Citations (Scopus)

Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes

Nakamura, K., Kamouchi, M., Kitazono, T., Kuroda, J., Shono, Y., Hagiwara, N., Ago, T., Ooboshi, H., Ibayashi, S. & Iida, M., May 1 2009, In : Microvascular Research. 77, 3, p. 327-334 8 p.

Research output: Contribution to journalArticle

Pericytes
Amiloride
Hydrogen Peroxide
Sodium-Hydrogen Antiporter
Acid Sensing Ion Channels
26 Citations (Scopus)

A region N-terminal to the tandem SH3 domain of p47phox plays a crucial role in the activation of the phagocyte NADPH oxidase

Taura, M., Miyano, K., Minakami, R., Kamakura, S., Takeya, R. & Sumimoto, H., Apr 15 2009, In : Biochemical Journal. 419, 2, p. 329-338 10 p.

Research output: Contribution to journalArticle

src Homology Domains
NADPH Oxidase
Phagocytes
Oxidoreductases
Chemical activation
38 Citations (Scopus)

Breastfeeding and atopic eczema in Japanese infants: The Osaka Maternal and Child Health Study

Miyake, Y., Tanaka, K., Sasaki, S., Kiyohara, C., Ohya, Y., Fukushima, W., Yokoyama, T. & Hirota, Y., May 1 2009, In : Pediatric Allergy and Immunology. 20, 3, p. 234-241 8 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Breast Feeding
Mothers
Postpartum Period
Asthma
71 Citations (Scopus)

Causal relationship between indium compound inhalation and effects on the lungs

Nakano, M., Omae, K., Tanaka, A., Hirata, M., Michikawa, T., Kikuchi, Y., Yoshioka, N., Nishiwaki, Y. & Chonan, T., Nov 1 2009, In : Journal of Occupational Health. 51, 6, p. 513-521 9 p.

Research output: Contribution to journalArticle

Indium
Inhalation
Lung
Pulmonary Surfactant-Associated Protein D
Serum
6 Citations (Scopus)

Change in clinical practice after publication of guidelines on breast cancer treatment

Fukuda, H., Imanaka, Y., Ishizaki, T., Okuma, K. & Shirai, T., Oct 2 2009, In : International Journal for Quality in Health Care. 21, 5, p. 372-378 7 p.

Research output: Contribution to journalArticle

Segmental Mastectomy
Publications
Guidelines
Breast Neoplasms
Japan
30 Citations (Scopus)

Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population

Kiyohara, C., Washio, M., Horiuchi, T., Tada, Y., Asami, T., Ide, S., Takahashi, H., Kobashi, G., Kodama, H., Akashi, K., Harada, M., Tsukamoto, H., Hotokebuchi, T., Nagasawa, K., Ushiyama, O., Mori, M., Oura, A., Sinomura, Y., Suzuki, H., Yamamoto, M. & 10 others, Abe, T., Tanaka, H., Nogami, N., Okamoto, K., Sakamoto, N., Sasaki, S., Miyake, Y., Yokoyama, T., Inaba, Y. & Nagai, M., Jan 1 2009, In : Lupus. 18, 7, p. 630-638 9 p.

Research output: Contribution to journalArticle

Acetyltransferases
Systemic Lupus Erythematosus
Smoking
Population
Genotype
19 Citations (Scopus)

Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population

Kiyohara, C., Washio, M., Horiuchi, T., Tada, Y., Asami, T., Ide, S., Atsumi, T., Kobashi, G., Takahashi, H., Kodama, H., Akashi, K., Harada, M., Tsukamoto, H., Hotokebuchi, T., Nagasawa, K., Ushiyama, O., Mori, M., Oura, A., Sinomura, Y., Suzuki, H. & 14 others, Yamamoto, M., Horita, T., Koike, T., Abe, T., Tanaka, H., Nogami, N., Okamoto, K., Sakamoto, N., Sasaki, S., Miyake, Y., Yokoyama, T., Hirota, Y., Inaba, Y. & Nagai, M., Oct 1 2009, In : Journal of Rheumatology. 36, 10, p. 2195-2203 9 p.

Research output: Contribution to journalArticle

STAT4 Transcription Factor
Receptors, Tumor Necrosis Factor, Type II
Systemic Lupus Erythematosus
Smoking
Population
1 Citation (Scopus)

Cilostamide produces hyperpolarization associated with katp channel activation, but does not augment endothelium-derived hyperpolarization in rat mesenteric arteries

Kansui, Y., Goto, K., Fujii, K., Oniki, H., Matsumura, K. & Iida, M., Jul 1 2009, In : Clinical and Experimental Pharmacology and Physiology. 36, 7, p. 729-733 5 p.

Research output: Contribution to journalArticle

Mesenteric Arteries
Endothelium
Glyburide
Acetylcholine
KATP Channels
14 Citations (Scopus)

Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE: Findings from the KYSS study

Horiuchi, T., Washio, M., Kiyohara, C., Tsukamoto, H., Tada, Y., Asami, T., Ide, S., Kobashi, G. & Takahashi, H., Sep 1 2009, In : Rheumatology. 48, 9, p. 1045-1049 5 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Cytochromes
Genes
Genotype
Odds Ratio
203 Citations (Scopus)

Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial

Zoungas, S., De Galan, B. E., Ninomiya, T., Grobbee, D., Hamet, P., Heller, S., MacMahon, S., Marre, M., Neal, B., Patel, A., Woodward, M. & Chalmers, J., Nov 1 2009, In : Diabetes care. 32, 11, p. 2068-2074 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Blood Pressure
Glucose
Gliclazide
perindopril drug combination indapamide
4 Citations (Scopus)

Correlation between increased urinary sodium excretion and decreased left ventricular diastolic function in patients with type 2 diabetes mellitus

Kagiyama, S., Koga, T., Kaseda, S., Ishihara, S., Kawazoe, N., Sadoshima, S., Matsumura, K., Takata, Y., Tsuchihashi, T. & Iida, M., Dec 4 2009, In : Clinical Cardiology. 32, 10, p. 569-574 6 p.

Research output: Contribution to journalArticle

Left Ventricular Function
Type 2 Diabetes Mellitus
Sodium
Diabetes Mellitus
Multivariate Analysis
25 Citations (Scopus)

Development and validation of a cardiovascular risk prediction model for Japanese: The Hisayama study

Arima, H., Yonemoto, K., Doi, Y., Ninomiya, T., Hata, J., Tanizaki, Y., Fukuhara, M., Matsumura, K., Iida, M. & Kiyohara, Y., Dec 23 2009, In : Hypertension Research. 32, 12, p. 1119-1122 4 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Myocardial Infarction
Population
Blood Pressure
Sudden Cardiac Death
39 Citations (Scopus)

Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: The Hisayama Study

Osawa, H., Doi, Y., Makino, H., Ninomiya, T., Yonemoto, K., Kawamura, R., Hata, J., Tanizaki, Y., Iida, M. & Kiyohara, Y., Nov 18 2009, In : Cardiovascular Diabetology. 8, 60.

Research output: Contribution to journalArticle

Resistin
Stroke
Hypertension
Serum
Population
8 Citations (Scopus)

Does decreased diastolic blood pressure associate with increased mortality in 80-year-old japanese

Kagiyama, S., Takata, Y., Ansai, T., Matsumura, K., Soh, I., Awano, S., Sonoki, K., Yoshida, A., Torisu, T., Hamasaki, T., Nakamichi, I., Takehara, T. & Iida, M., Dec 1 2009, In : Clinical and Experimental Hypertension. 31, 8, p. 639-647 9 p.

Research output: Contribution to journalArticle

Blood Pressure
Mortality
Cardiovascular Diseases
Hypertension
Pneumonia
76 Citations (Scopus)

Effect of anterior cruciate ligament reconstruction and meniscectomy on length of career in National football League athletes: A Case control Study

Brophy, R. H., Gill, C. S., Lyman, S., Barnes, R. P., Rodeo, S. A. & Warren, R. F., Dec 2 2009, In : American Journal of Sports Medicine. 37, 11, p. 2102-2107 6 p.

Research output: Contribution to journalArticle

Anterior Cruciate Ligament Reconstruction
Football
Athletes
Case-Control Studies
Anterior Cruciate Ligament
19 Citations (Scopus)

Effects of the end point adjudication process on the results of the perindopril protection against recurrent stroke study (PROGRESS)

Ninomiya, T., Donnan, G., Anderson, N., Bladin, C., Chambers, B., Gordon, G., Sharpe, N., Chalmers, J., Woodward, M. & Neal, B., Jun 1 2009, In : Stroke. 40, 6, p. 2111-2115 5 p.

Research output: Contribution to journalArticle

Perindopril
Stroke
Research Personnel
Cerebrovascular Disorders
Preexisting Condition Coverage
240 Citations (Scopus)

Epidemiology of anterior cruciate ligament reconstruction. Trends, readmissions, and subsequent knee surgery

Lyman, S., Koulouvaris, P., Sherman, S., Do, H., Mandl, L. A. & Marx, R. G., Oct 1 2009, In : Journal of Bone and Joint Surgery - Series A. 91, 10, p. 2321-2328 8 p.

Research output: Contribution to journalArticle

Anterior Cruciate Ligament Reconstruction
Knee
Epidemiology
Ambulatory Surgical Procedures
Patient Readmission
2 Citations (Scopus)

Flow Volume and Cross-Sectional Area of the Extracranial Vertebral Arteries and its Relation to Vascular Lesions or Anatomical Variations in the Posterior Circulation

Wakugawa, Y., Sugimori, H., Nakane, H., Hata, J., Irie, K., Kitazono, T. & Iida, M., Jul 1 2009, In : Ultrasound in Medicine and Biology. 35, 7, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

Vertebral Artery
arteries
lesions
Blood Vessels
Magnetic Resonance Angiography
122 Citations (Scopus)

FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation

Yoshimoto, G., Miyamoto, T., Jabbarzadeh-Tabrizi, S., Iino, T., Rocnik, J. L., Kikushige, Y., Mori, Y., Shima, T., Iwasaki, H., Takenaka, K., Nagafuji, K., Mizuno, S. I., Niiro, H., Gilliland, G. D. & Akashi, K., Dec 3 2009, In : Blood. 114, 24, p. 5034-5043 10 p.

Research output: Contribution to journalArticle

STAT5 Transcription Factor
Myeloid Leukemia
Myeloid Cells
Stem cells
Acute Myeloid Leukemia
79 Citations (Scopus)

Hyperglycemia Increases Risk of Gastric Cancer Posed by Helicobacter pylori Infection: A Population-Based Cohort Study

Ikeda, F., Doi, Y., Yonemoto, K., Ninomiya, T., Kubo, M., Shikata, K., Hata, J., Tanizaki, Y., Matsumoto, T., Iida, M. & Kiyohara, Y., Apr 2009, In : Gastroenterology. 136, 4, p. 1234-1241 8 p.

Research output: Contribution to journalArticle

Helicobacter Infections
Helicobacter pylori
Hyperglycemia
Stomach Neoplasms
Cohort Studies
103 Citations (Scopus)

Identification of the human eosinophil lineage-committed progenitor: Revision of phenotypic definition of the human common myeloid progenitor

Mori, Y., Iwasaki, H., Kohno, K., Yoshimoto, G., Kikushige, Y., Okeda, A., Uike, N., Niiro, H., Takenaka, K., Nagafuji, K., Miyamoto, T., Harada, M., Takatsu, K. & Akashi, K., Jan 16 2009, In : Journal of Experimental Medicine. 206, 1, p. 183-193 11 p.

Research output: Contribution to journalArticle

Myeloid Progenitor Cells
Forensic Anthropology
Eosinophils
Eosinophilia
Megakaryocyte-Erythroid Progenitor Cells
25 Citations (Scopus)

Impact of blood pressure levels on different types of stroke: The Hisayama study

Arima, H., Tanizaki, Y., Yonemoto, K., Doi, Y., Ninomiya, T., Hata, J., Fukuhara, M., Matsumura, K., Iida, M. & Kiyohara, Y., Dec 1 2009, In : Journal of hypertension. 27, 12, p. 2437-2443 7 p.

Research output: Contribution to journalArticle

Stroke
Blood Pressure
Infarction
Hypertension
Lacunar Stroke
31 Citations (Scopus)

Impact of metabolic syndrome compared with impaired fasting glucose on the development of type 2 diabetes in a general Japanese population: The Hisayama study

Mukai, N., Doi, Y., Ninomiya, T., Hata, J., Yonemoto, K., Iwase, M., Iida, M. & Kiyohara, Y., Dec 1 2009, In : Diabetes care. 32, 12, p. 2288-2293 6 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Fasting
Glucose
Population
Age Factors
9 Citations (Scopus)

Improvement of blood pressure control in a hypertension clinic in Japan: A 15-year follow-up study

Ohta, Y., Matsumura, K., Tsuchihashi, T., Ohtsubo, T., Arima, H., Miwa, Y., Goto, K., Ohya, Y., Fujii, K., Uezono, K., Abe, I. & Iida, M., Nov 1 2009, In : Clinical and Experimental Hypertension. 31, 7, p. 553-559 7 p.

Research output: Contribution to journalArticle

Japan
Blood Pressure
Hypertension
Antihypertensive Agents
Diuretics
80 Citations (Scopus)

Incidence and survival of dementia in a general population of Japanese elderly: The hisayama study

Matsui, Y., Tanizaki, Y., Arima, H., Yonemoto, K., Doi, Y., Ninomiya, T., Sasaki, K., Iida, M., Iwaki, T., Kanba, S. & Kiyohara, Y., Apr 1 2009, In : Journal of Neurology, Neurosurgery and Psychiatry. 80, 4, p. 366-370 5 p.

Research output: Contribution to journalArticle

Dementia
Survival
Incidence
Population
Vascular Dementia
178 Citations (Scopus)

Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota

Tanaka, S., Kobayashi, T., Songjinda, P., Tateyama, A., Tsubouchi, M., Kiyohara, C., Shirakawa, T., Sonomoto, K. & Nakayama, J., Jun 1 2009, In : FEMS Immunology and Medical Microbiology. 56, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Anti-Bacterial Agents
Bifidobacterium
Enterococcus
Beginning of Human Life
Gastrointestinal Microbiome
39 Citations (Scopus)

Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice

Tanaka, R., Miwa, Y., Mou, K., Tomikawa, M., Eguchi, N., Urade, Y., Takahashi-Yanaga, F., Morimoto, S., Wake, N. & Sasaguri, T., Jan 23 2009, In : Biochemical and Biophysical Research Communications. 378, 4, p. 851-856 6 p.

Research output: Contribution to journalArticle

prostaglandin R2 D-isomerase
Lipocalins
Atherosclerosis
Obesity
Genes
29 Citations (Scopus)

Lack of association between variations of PDE4D and ischemic stroke in the Japanese population

Matsushita, T., Kubo, M., Yonemoto, K., Ninomiya, T., Ashikawa, K., Liang, B., Hata, J., Doi, Y., Kitazono, T., Ibayashi, S., Iida, M., Kiyohara, Y. & Nakamura, Y., Apr 1 2009, In : Stroke. 40, 4, p. 1245-1251 7 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Stroke
Haplotypes
Population
Japan
213 Citations (Scopus)

Lowering blood pressure reduces renal events in type 2 diabetes

De Galan, B. E., Perkovic, V., Ninomiya, T., Pillai, A., Patel, A., Cass, A., Neal, B., Poulter, N., Harrap, S., Mogensen, C. E., Cooper, M., Marre, M., Williams, B., Hamet, P., Mancia, G., Woodward, M., Glasziou, P., Grobbee, D. E., MacMahon, S. & Chalmers, J., Apr 1 2009, In : Journal of the American Society of Nephrology. 20, 4, p. 883-892 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Indapamide
Perindopril
Blood Pressure
Kidney
10 Citations (Scopus)

Maternal smoking during pregnancy and offspring attention-deficit/hyperactivity disorder: a case-control study in Japan.

Yoshimasu, K., Kiyohara, C., Minami, T., Yoshikawa, N., Kihira, S., Toyonaga, K., Yamamoto, A., Shinosaki, K., Yamashita, H., Miyashita, K. & Wakayama ADHD Study Group, ADHD. S. G., Dec 1 2009, In : Attention deficit and hyperactivity disorders. 1, 2, p. 223-231 9 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Case-Control Studies
Japan
Smoking
Mothers
21 Citations (Scopus)

Midkine gene transfer protects against focal brain ischemia and augments neurogenesis

Ishikawa, E., Ooboshi, H., Kumai, Y., Takada, J., Nakamura, K., Ago, T., Sugimori, H., Kamouchi, M., Kitazono, T., Ibayashi, S. & Iida, M., Oct 15 2009, In : Journal of the Neurological Sciences. 285, 1-2, p. 78-84 7 p.

Research output: Contribution to journalArticle

Neurogenesis
Brain Ischemia
Brain Infarction
Cerebrovascular Circulation
Fluorescence
72 Citations (Scopus)

Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells

Koyama, M., Hashimoto, D., Aoyama, K., Matsuoka, K. I., Karube, K., Niiro, H., Harada, M., Tanimoto, M., Akashi, K. & Teshima, T., Feb 26 2009, In : Blood. 113, 9, p. 2088-2095 8 p.

Research output: Contribution to journalArticle

T-cells
Graft vs Host Disease
Antigen-Presenting Cells
Grafts
Dendritic Cells
52 Citations (Scopus)

Proposed criteria for metabolic syndrome in Japanese based on prospective evidence the hisayama study

Doi, Y., Ninomiya, T., Hata, J., Yonemoto, K., Arima, H., Kubo, M., Tanizaki, Y., Iwase, M., Iida, M. & Kiyohara, Y., Apr 1 2009, In : Stroke. 40, 4, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Waist Circumference
Independent Living
Abdominal Obesity
Prospective Studies
7 Citations (Scopus)

Propyl gallate, a strong antioxidant, increases the ca2+ sensitivity of cardiac myofilament

Tadano, N., Morimoto, S., Takahashi-Yanaga, F., Miwa, Y., Ohtsuki, I. & Sasaguri, T., Jun 22 2009, In : Journal of Pharmacological Sciences. 109, 3, p. 456-458 3 p.

Research output: Contribution to journalArticle

Propyl Gallate
Myofibrils
Antioxidants
Cardiotonic Agents
Myocardium
116 Citations (Scopus)

Prospective analysis of arthroscopic rotator cuff repair: Prognostic factors affecting clinical and ultrasound outcome

Nho, S. J., Brown, B. S., Lyman, S., Adler, R. S., Altchek, D. W. & MacGillivray, J. D., Jan 1 2009, In : Journal of Shoulder and Elbow Surgery. 18, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

Rotator Cuff
Tendons
Odds Ratio
Confidence Intervals
Tears
15 Citations (Scopus)

PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL

Ueno, S., Tatetsu, H., Hata, H., Iino, T., Niiro, H., Akashi, K., Tenen, D. G., Mitsuya, H. & Okuno, Y., Nov 1 2009, In : Oncogene. 28, 46, p. 4116-4125 10 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Transcriptional Activation
Apoptosis
Cyclin A2
Down-Regulation
18 Citations (Scopus)

Role for the first SH3 domain of p67phox in activation of superoxide-producing NADPH oxidases

Maehara, Y., Miyano, K. & Sumimoto, H., Feb 6 2009, In : Biochemical and Biophysical Research Communications. 379, 2, p. 589-593 5 p.

Research output: Contribution to journalArticle

src Homology Domains
NADPH Oxidase
Superoxides
Chemical activation
Oxidoreductases
21 Citations (Scopus)

Seroprevalence of herpes simplex virus 1 and 2 in a population-based cohort in Japan

Doi, Y., Ninomiya, T., Hata, J., Yonemoto, K., Tanizaki, Y., Arima, H., Liu, Y., Rahman, M., Iida, M. & Kiyohara, Y., Jun 9 2009, In : Journal of epidemiology. 19, 2, p. 56-62 7 p.

Research output: Contribution to journalArticle

Human Herpesvirus 2
Seroepidemiologic Studies
Human Herpesvirus 1
Japan
Population
35 Citations (Scopus)
Galectin 1
T-Cell Leukemia
T-Cell Lymphoma
Immunoglobulin M
B-Lymphocytes