Department of Medical Education

Research Output 1983 2020

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1997

Functional expression of human interleukin-4 receptor α gene on a mouse macrophage cell line

Qtsukar, T., Nemoto, X., Yamaqka, K., Nakasfflma, H., Niiro, H., Tanaka, Y., Qhgaml, E., Arinqbu, Y., Niho, Y. & Kenji, I., Dec 1 1997, In : Japanese Journal of Human Genetics. 42, 1, 1 p.

Research output: Contribution to journalArticle

Interleukin-4
Macrophages
Interleukin-4 Receptors
Cell Line
Genes
12 Citations (Scopus)

Membrane currents evoked by histamine in rabbit basilar artery

Kamouchi, M., Ogata, R., Fujishima, M., Ito, Y. & Kitamura, K., Feb 1 1997, In : American Journal of Physiology - Heart and Circulatory Physiology. 272, 2 41-2, p. H638-H647

Research output: Contribution to journalArticle

Basilar Artery
Histamine
Rabbits
Membranes
Baths
9 Citations (Scopus)

Methicillin-resistant Staphylococcus aureus (MRSA) isolation from pharyngeal swab cultures of Japanese elderly at admission to a geriatric hospital

Washio, M., Kiyohara, C., Honjo, N., Aoyagi, K., Okada, K., Arai, Y., Fujishima, M. & Ito, Y., Jan 1 1997, In : Journal of epidemiology. 7, 3, p. 167-172 6 p.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Geriatrics
Activities of Daily Living
Nursing Homes
Serum Albumin

Relationship between chemically induced cell damage and aryl hydrocarbon hydroxylase activity in several lymphoblastoid cell lines

Kiyohara, C., Washio, M. & Hirohata, T., Oct 30 1997, In : Medical Science Research. 25, 9, p. 611-614 4 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Hydroxylases
Xeroderma Pigmentosum
Ataxia Telangiectasia
Cells
Homozygote
31 Citations (Scopus)

Relationship of alcohol use, physical activity and dietary habits with serum carotenoids, retinol and alpha-tocopherol among male Japanese smokers

Kitamura, Y., Tanaka, K., Kiyohara, C., Hirohata, T., Tomita, Y., Ishibashi, M. & Kido, K., Apr 1997, In : International Journal of Epidemiology. 26, 2, p. 307-314 8 p.

Research output: Contribution to journalArticle

alpha-Tocopherol
Feeding Behavior
Carotenoids
Vitamin A
Alcohols
27 Citations (Scopus)

Risk factors for left ventricular hypertrophy in chronic hemodialysis patients

Washio, M., Okuda, S., Mizoue, T., Kiyama, S., Ando, T., Sanai, T., Hirakata, H., Nanishi, F., Kiyohara, C., Ogimoto, I., Yoshimura, T. & Fujishima, M., Jul 9 1997, In : Clinical nephrology. 47, 6, p. 362-366 5 p.

Research output: Contribution to journalArticle

Left Ventricular Hypertrophy
Renal Dialysis
Blood Pressure
Hematocrit
Weight Gain
22 Citations (Scopus)

Role of ATP-sensitive potassium channels in brain stem circulation during hypotension

Toyoda, K., Fujii, K., Ibayashi, S., Kitazono, T., Nagao, T. & Fujishima, M., Dec 1 1997, In : American Journal of Physiology. 273, 3 PART 2

Research output: Contribution to journalArticle

Cerebrovascular Circulation
KATP Channels
Arterioles
Hypotension
Brain Stem
13 Citations (Scopus)

Role of Ca2+-activated K+ channels in acetylcholine-induced dilatation of the basilar artery in vivo

Kitazono, T., Ibayashi, S., Nagao, T., Fujii, K. & Fujishima, M., Feb 1 1997, In : British Journal of Pharmacology. 120, 1, p. 102-106 5 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Basilar Artery
Acetylcholine
Dilatation
Large-Conductance Calcium-Activated Potassium Channels
25 Citations (Scopus)

Role of nitric oxide in regulation of brain stem circulation during hypotension

Toyoda, K., Fujii, K., Ibayashi, S., Nagao, T., Kitazono, T. & Fujishima, M., Oct 1997, In : Journal of Cerebral Blood Flow and Metabolism. 17, 10, p. 1089-1096 8 p.

Research output: Contribution to journalArticle

Hypotension
Brain Stem
Nitric Oxide
Basilar Artery
Dilatation
7 Citations (Scopus)

The Case Fatality Rate of Methicillin-Resistant Staphylococcus aureus (MRSA) Infection among the Elderly in a Geriatric Hospital and Their Risk Factors

Washio, M., Kiyohara, C., Hamada, T., Miyake, Y., Arai, Y. & Okayama, M., Jan 1 1997, In : Tohoku Journal of Experimental Medicine. 183, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Geriatrics
Methicillin
Methicillin-Resistant Staphylococcus aureus
Mortality
Hypoalbuminemia
18 Citations (Scopus)

Treatment of hepatic encephalopathy by retrograde transcaval coil embolization of an ileal vein-to-right gonadal vein portosystemic shunt

Nishie, A., Yoshimitsu, K., Honda, H., Kaneko, K., Kuroiwa, T., Fukuya, T., Irie, H., Ninomiya, T., Yoshimitsu, T., Hirakata, H., Okuda, S. & Masuda, K., May 1 1997, In : CardioVascular and Interventional Radiology. 20, 3, p. 222-224 3 p.

Research output: Contribution to journalArticle

Surgical Portasystemic Shunt
Hepatic Encephalopathy
Brain Diseases
Veins
Stainless Steel
1996
28 Citations (Scopus)

Altered cerebrovascular response to a potassium channel opener in hypertensive rats

Takaba, H., Nagao, T., Ibayashi, S., Kitazono, T., Fujii, K. & Fujishima, M., Jul 1996, In : Hypertension. 28, 1, p. 143-146 4 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Potassium Channels
KATP Channels
Inbred WKY Rats
Cilazapril
29 Citations (Scopus)

Chronic toxicity of indium arsenide and indium phosphide to the lungs of hamsters.

Tanaka, A., Hisanaga, A., Hirata, M., Omura, M., Makita, Y., Inoue, N. & Ishinishi, N., May 1996, In : Fukuoka igaku zasshi = Hukuoka acta medica. 87, 5, p. 108-115 8 p.

Research output: Contribution to journalArticle

Cricetinae
Lung
Control Groups
Mesocricetus
Emphysema
18 Citations (Scopus)

Circadian blood pressure in patients in a persistent vegetative state

Fukudome, Y., Abe, I., Saku, Y., Matsumura, K., Sadoshima, S., Utunomiya, H. & Fujishima, M., Jun 25 1996, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270, 5 39-5, p. R1109-R1114

Research output: Contribution to journalArticle

Persistent Vegetative State
Blood Pressure
Heart Rate
Sodium
17-Hydroxycorticosteroids
1 Citation (Scopus)

Circadian variations of blood pressure in patients with sequelae of carbon monoxide poisoning

Fukuhara, M., Abe, I., Matsumura, K., Kaseda, S., Yamashita, Y., Shida, K., Kawashima, H. & Fujishima, M., Jan 1 1996, In : American Journal of Hypertension. 9, 4 I, p. 300-305 6 p.

Research output: Contribution to journalArticle

Carbon Monoxide Poisoning
Blood Pressure
Globus Pallidus
Heart Rate
Brain
76 Citations (Scopus)

Effect of IL-10 on collagen-induced arthritis in mice

Tanaka, Y., Otsuka, T., Hotokebuchi, T., Miyahara, H., Nakashima, H., Kuga, S., Nemoto, Y., Niiro, H. & Niho, Y., Jul 11 1996, In : Inflammation Research. 45, 6, p. 283-288 6 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Interleukin-10
Arthritis
Cytokines
Collagen Type II
1406 Citations (Scopus)

Mice Lacking p27Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D. Y. & Nakayama, K. I., May 31 1996, In : Cell. 85, 5, p. 707-720 14 p.

Research output: Contribution to journalArticle

Retinal Dysplasia
Retinal Neoplasms
Thymus
Pituitary Neoplasms
Body Size
26 Citations (Scopus)

Role of area postrema in transgene hypertension

Averill, D. B., Matsumura, K., Ganten, D. & Ferrario, C. M., Mar 1 1996, In : Hypertension. 27, 3 II, p. 591-597 7 p.

Research output: Contribution to journalArticle

Area Postrema
Transgenes
Hypertension
Blood Pressure
Arterial Pressure

Role of cytochrome P4501A1 (CYP1A1) in lung cancer sensitivity

Kiyohara, C., Sep 1996, In : Fukuoka igaku zasshi = Hukuoka acta medica. 87, 9, p. 185-188 4 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP1A1
Cytochromes
Lung Neoplasms
58 Citations (Scopus)

Suppression of superoxide anion production by interleukin-10 is accompanied by a downregulation of the genes for subunit proteins of NADPH oxidase

Kuga, S., Otsuka, T., Niiro, H., Nunoi, H., Nemoto, Y., Nakano, T., Ogo, T., Umei, T. & Niho, Y., Mar 20 1996, In : Experimental Hematology. 24, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Superoxides
Interleukin-10
Down-Regulation
Proteins
39 Citations (Scopus)

Testicular toxicity evaluation of arsenic-containing binary compound semiconductors, gallium arsenide and indium arsenide, in hamsters

Omura, M., Hirata, M., Tanaka, A., Zhao, M., Makita, Y., Inoue, N., Gotoh, K. & Ishinishi, N., Dec 16 1996, In : Toxicology Letters. 89, 2, p. 123-129 7 p.

Research output: Contribution to journalArticle

Semiconductors
Arsenic
Cricetinae
Toxicity
Semiconductor materials
50 Citations (Scopus)

Testicular toxicity of gallium arsenide, indium arsenide, and arsenic oxide in rats by repetitive intratracheal instillation

Omura, M., Tanaka, A., Hirata, M., Zhao, M., Makita, Y., Inoue, N., Gotoh, K. & Ishinishi, N., Jul 1996, In : Fundamental and Applied Toxicology. 32, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

Arsenic
Oxides
Toxicity
Rats
Sperm Count
116 Citations (Scopus)

The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene

Kiyohara, C., Hirohata, T. & Inutsuka, S., Jan 1996, In : Japanese Journal of Cancer Research. 87, 1, p. 18-24 7 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP1A1
Genotype
Genes
isoleucylvaline
1995
36 Citations (Scopus)

A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies

Baba, E., Nakamura, M., Ohkuma, K., Kira, J. I., Tanaka, Y., Nakano, S. & Niho, Y., Jan 1 1995, In : Journal of Immunology. 154, 1, p. 399-412 14 p.

Research output: Contribution to journalArticle

B-Lymphocyte Epitopes
Human T-lymphotropic virus 1
T-Lymphocyte Epitopes
Neutralizing Antibodies
Vaccines
1 Citation (Scopus)

Chronic toxicity of tar from heavy-duty diesel exhaust following intratracheal instillations to the lungs of hamsters

Tanaka, A., Hisanaga, A., Hirata, M., Omura, M., Makita, Y., Inoue, N. & Ishinishi, N., Jan 1 1995, In : Fukuoka Acta Medica. 86, 2, p. 65-73 9 p.

Research output: Contribution to journalArticle

Tars
Vehicle Emissions
Cricetinae
Lung
Papilloma
24 Citations (Scopus)
Chlorohydrins
alpha-Chlorohydrin
Epichlorohydrin
Propane
Seminiferous Tubules
1 Citation (Scopus)

Effects of polychlorinated dibenzo-p-dioxin and dibenzofuran congeners in human lymphoblastoid cells on aryl hydrocarbon hydroxylase activity

Kiyohara, C., Hirohata, T. & Masuda, Y., Oct 1995, In : Chemosphere. 31, 7, p. 3673-3680 8 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Hydroxylases
dibenzofuran
dioxin
Hydrocarbons
hydrocarbon
88 Citations (Scopus)

Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: Its underlying mechanism in comparison with interleukin-4

Niiro, H., Otsuka, T., Tanabe, T., Hara, S., Kuga, S., Nemoto, Y., Tanaka, Y., Nakashima, H., Kitajima, S., Abe, M. & Niho, Y., Jan 1 1995, In : Blood. 85, 12, p. 3736-3745 10 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
Interleukin-4
Interleukin-10
Lipopolysaccharides
3 Citations (Scopus)

Inhibitory Effects of Interleukin (IL)-10 and Viral IL-10 (vIL-10) on the Functions of Monocytes/Macrophages

Nemoto, Y., Otsuka, T., Niiro, H., Kuga, S., Tanaka, Y., Nakashima, H. & Niho, Y., Jan 1 1995, In : Japanese Journal of Clinical Immunology. 18, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

Interleukin-10
Monocytes
Macrophages
Interferons
Nitric Oxide
86 Citations (Scopus)

Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats

Moriguchi, A., Tallant, E. A., Matsumura, K., Reilly, T. M., Walton, H., Ganten, D. & Ferrario, C. M., Jun 1995, In : Hypertension. 25, 6, p. 1260-1265 6 p.

Research output: Contribution to journalArticle

Transgenic Rats
Angiotensin II
Antibodies
Brain
Lisinopril
20 Citations (Scopus)

Phenylarsine oxide inhibits tyrosine phosphorylation of phospholipase Cγ2 in human platelets and phospholipase Cγ1 in NIH-3T3 fibroblasts

Yanaga, F., Asselin, J., Schieven, G. L. & Watson, S. P., Jul 17 1995, In : FEBS Letters. 368, 2, p. 377-380 4 p.

Research output: Contribution to journalArticle

Phosphorylation
Phospholipases
Fibroblasts
Platelets
Tyrosine
86 Citations (Scopus)

Polymorphisms of human Ah receptor gene are not involved in lung cancer

Kawajiri, K., Watanabe, J., Eguchi, H., Nakachi, K., Kiyohara, C. & Hayashi, S. I., Jun 1995, In : Pharmacogenetics. 5, 3, p. 151-158 8 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Gene Pool
Cytochrome P-450 CYP1A1
Germ Cells
Codon
9 Citations (Scopus)

Short Communication Toxic Effects of Gallium Arsenide on Sperm in Rats by Repeated Intratracheal Instillations

Omura, M., Tanaka, A., Zhao, M., Hirata, M., Maxita, Y., Inoue, N. & Gotoh, K., Jan 1 1995, In : Journal of Occupational Health. 37, 3, 1 p.

Research output: Contribution to journalArticle

Poisons
Semiconductor lasers
Spermatozoa
Rats
Communication
123 Citations (Scopus)

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fcγ-IIA receptor

Yanaga, F., Poole, A., Asselin, J., Blake, R., Schieven, G. L., Clark, E. A., Law, C. L. & Watson, S. P., Jan 1 1995, In : Biochemical Journal. 311, 2, p. 471-478 8 p.

Research output: Contribution to journalArticle

Fc Receptors
Platelets
Tyrosine
Collagen
Blood Platelets
1994
33 Citations (Scopus)

Ceramide does not mediate the effect of tumour necrosis factor α on superoxide generation in human neutrophils

Takahashi, F. & Watson, S. P., Jan 1 1994, In : Biochemical Journal. 298, 3, p. 733-738 6 p.

Research output: Contribution to journalArticle

Ceramides
Superoxides
Neutrophils
Tumor Necrosis Factor-alpha
Sphingomyelin Phosphodiesterase
2 Citations (Scopus)

Cerebellar Vermis Bleeding in a Patient with Hemophilia A: A Case Report

Kitazono, T., Okada, Y., Sadoshima, S., Utsunomiya, H. & Fujishima, M., Apr 1994, In : Angiology. 45, 4, p. 321-324 4 p.

Research output: Contribution to journalArticle

Hemophilia A
Craniocerebral Trauma
Neurologic Gait Disorders
Hemorrhage
Factor VIII
3 Citations (Scopus)

Dose-dependent testicular toxicity of propylene oxide in rats induced by repeated intraperitoneal injections

Omura, M., Tanaka, A., Mori, K., Hirata, M., Zao, M. & Inoue, N., Jan 1 1994, In : Fukuoka Acta Medica. 85, 7, p. 204-210 7 p.

Research output: Contribution to journalArticle

Intraperitoneal Injections
Sperm Count
Leydig Cells
Epididymis
Testosterone

Editorial comment

Kitazono, T., Jan 1 1994, In : Stroke. 25, 7, 1 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
Aryl Hydrocarbon Hydroxylases
Benzo(a)pyrene
Polychlorinated Biphenyls
Metabolites
Ascorbic Acid
8 Citations (Scopus)

Expression of the c‐kit ligand and interleukin 6 genes in mouse bone marrow stromal cell lines

Otsuka, T., Ogo, T., Nakano, T., Niiro, H., Kuga, S., Satoh, H., Furukawa, Y., Niho, Y. & Zipori, D., 1994, In : STEM CELLS. 12, 4, p. 409-415 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Interleukin-6
Ligands
Cell Line
Stromal Cells
15 Citations (Scopus)

Modulation of circadian rhythm of blood pressure by cortisol in patients with hypopituitarism

Matsumura, K., Abe, I., Fukuhara, M., Fujii, K., Ohya, Y., Okamura, K. & Fujishima, M., Jan 1 1994, In : Clinical and Experimental Hypertension. 16, 1, p. 55-66 12 p.

Research output: Contribution to journalArticle

Hypopituitarism
Circadian Rhythm
Hydrocortisone
Blood Pressure
Prednisolone
21 Citations (Scopus)

Naloxone augments sympathetic outflow induced by centrally administered endothelin in conscious rabbits

Matsumura, K., Abe, I., Fukuhara, M., Tominaga, M., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., Jan 1 1994, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 266, 4 35-4, p. R1403-R1410

Research output: Contribution to journalArticle

Endothelins
Naloxone
Endothelin-1
Baroreflex
Rabbits

Naloxone augments sympathetic outflow induced by centrally administered endothelin in conscious rabbits

Matsumura, K., Abe, I., Fukuhara, M., Tominaga, M., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., 1994, In : AM.J.PHYSIOL.. 266, 4 part 2

Research output: Contribution to journalArticle

naloxone
endothelins
Endothelins
Naloxone
rabbits
16 Citations (Scopus)

Pulmonary toxicity of indium arsenide and arsenic selenide following repeated intratracheal instillations to the lungs of hamsters

Tanaka, A., Hisanaga, A., Hirata, M., Omura, M., Inoue, N. & Ishinishi, N., May 1994, In : Applied Organometallic Chemistry. 8, 3, p. 265-271 7 p.

Research output: Contribution to journalArticle

Arsenic
Toxicity
Tumors
indium arsenide
Buffers
46 Citations (Scopus)
Diphosphates
Portal Vein
Nucleotides
Adenosine Triphosphate
Rabbits
31 Citations (Scopus)

Sequence heterogeneity of HTLV‐I proviral DNA in the central nervous system of patients with HTLV‐I–associated myelopathy

Kira, J. ., Koyanagi, Y., Yamada, T., Itoyama, Y., Tateishi, J., Akizuki, S. ., Kishikawa, M., Baba, E., Nakamura, M., Suzuki, J., Nakamura, T., Nakamura, N., Yamamoto, N. & Goto, I., Aug 1994, In : Annals of Neurology. 36, 2, p. 149-156 8 p.

Research output: Contribution to journalArticle

Tropical Spastic Paraparesis
Spinal Cord Diseases
Central Nervous System
Viruses
DNA
1993
11 Citations (Scopus)

A target K+ channel for the LP-805-induced hyperpolarization in smooth muscle cells of the rabbit portal vein

Kamouchi, M., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Mar 1993, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 347, 3, p. 329-335 7 p.

Research output: Contribution to journalArticle

Portal Vein
Smooth Muscle Myocytes
Rabbits
Large-Conductance Calcium-Activated Potassium Channels
Charybdotoxin
4 Citations (Scopus)

CIRCADIAN VARIATIONS OF BLOOD PRESSURE AND PULSE RATE IN ESSENTIAL HYPERTENSIVES WITH DIABETES MELLITUS

Matsumura, K., Abe, I., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., Mar 1993, In : Clinical and Experimental Pharmacology and Physiology. 20, 3, p. 155-160 6 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Heart Rate
Blood Pressure
Orthostatic Hypotension
Circadian Rhythm
5 Citations (Scopus)

Invasive Development of Right Atrial Myxoma— A Case Report

Nakayama, M., Matsumura, K., Abe, I., Kaku, R., Kobayashi, K., Fujishima, M., Aso, H., Tokunaga, K. & Ishii, Y., Sep 1993, In : Angiology. 44, 9, p. 739-744 6 p.

Research output: Contribution to journalArticle

Myxoma
Heart Atria
Brachiocephalic Veins
Superior Vena Cava
Thrombosis
2 Citations (Scopus)

In vivo effect of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mouse liver microsomes

Chikako, K. & Tomio, H., Feb 1993, In : Toxicology Letters. 66, 2, p. 199-207 9 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Hydroxylases
Methylcholanthrene
Liver Microsomes
Liver
Dichlorodiphenyldichloroethane