Research Output 1983 2019

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Review article
2019
Open Access
Cross-Sectional Studies
Smoking
Population
Japan
Environmental Pollution
2018
2 Citations (Scopus)

Anticancer drug treatment for advanced lung cancer with interstitial lung disease

Otsubo, K., Okamoto, I., Hamada, N. & Nakanishi, Y., Jul 2018, In : Respiratory Investigation. 56, 4, p. 307-311 5 p.

Research output: Contribution to journalReview article

Interstitial Lung Diseases
Lung Neoplasms
Pharmaceutical Preparations
Drug Therapy
Therapeutics
3 Citations (Scopus)

Combined therapy with epidermal growth factor receptor tyrosine kinase inhibitors for non–small cell lung cancer

Iwama, E., Nakanishi, Y. & Okamoto, I., Mar 4 2018, In : Expert Review of Anticancer Therapy. 18, 3, p. 267-276 10 p.

Research output: Contribution to journalReview article

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Therapeutics
2 Citations (Scopus)

Preclinical Toxicity Studies for Regenerative Medicine in Japan

Shigeto, J., Ichiki, T., Nii, T., Konno, K., Nakanishi, Y. & Sugiyama, D., Nov 1 2018, In : Clinical Therapeutics. 40, 11, p. 1813-1822 10 p.

Research output: Contribution to journalReview article

Regenerative Medicine
Japan
Guidelines
Pharmaceutical Preparations
Heterologous Immunity
2016
4 Citations (Scopus)

Biomimetic peptides for the treatment of cancer

Mine, Y., Munir, H., Nakanishi, Y. & Sugiyama, D., Jan 1 2016, In : Anticancer research. 36, 7, p. 3565-3570 6 p.

Research output: Contribution to journalReview article

Biomimetics
Peptides
Neoplasms
Proteins
Cellular Microenvironment
2015
5 Citations (Scopus)

Implementation of modern therapy approaches and research for non-small cell lung cancer in Japan

Nakanishi, Y., Feb 1 2015, In : Respirology. 20, 2, p. 199-208 10 p.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Lung Neoplasms
Japan
Research
Therapeutics
2014
1 Citation (Scopus)

[Personalized medicine in non-small-cell carcinoma].

Iwama, E., Takayama, K., Baba, E. & Nakanishi, Y., Jan 1 2014, In : Fukuoka igaku zasshi = Hukuoka acta medica. 105, 3, p. 57-66 10 p.

Research output: Contribution to journalReview article

Serine Endopeptidases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Antineoplastic Combined Chemotherapy Protocols
Molecular Targeted Therapy
3 Citations (Scopus)

Current status and future perspectives of cooperative study groups for lung cancer in Japan

Kawano, Y., Okamoto, I., Fukuda, H., Ohe, Y., Nakamura, S., Nakagawa, K., Hotta, K., Kiura, K., Takiguchi, Y., Saka, H., Okamoto, H., Takayama, K., Semba, H., Kobayashi, K., Kenmotsu, H., Tsuboi, M., Yamamoto, N., Nukiwa, T. & Nakanishi, Y., Nov 1 2014, In : Respiratory Investigation. 52, 6, p. 339-347 9 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Japan
Clinical Trials
Research Personnel
Therapeutics
32 Citations (Scopus)

Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer

Iwama, E., Okamoto, I., Harada, T., Takayama, K. & Nakanishi, Y., Mar 5 2014, In : OncoTargets and Therapy. 7, p. 375-385 11 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Non-Small Cell Lung Carcinoma
anaplastic lymphoma kinase
United States Food and Drug Administration
Oncogenes
8 Citations (Scopus)

Intrinsic and extrinsic regulation of mammalian hematopoiesis in the fetal liver

Swain, A., Inoue, T., Tan, K. S., Nakanishi, Y. & Sugiyama, D., Sep 2014, In : Histology and histopathology. 29, 9, p. 1077-1082 6 p.

Research output: Contribution to journalReview article

Hematopoiesis
Liver
Stromal Cells
Endothelial Cells
Erythroid Cells

Regulation of infection in chronic airway inflammation

Matsumoto, K., Feb 1 2014, In : Respiration and Circulation. 62, 2, p. 114-120 7 p.

Research output: Contribution to journalReview article

Inflammation
Infection
33 Citations (Scopus)

Viral infections in asthma and COPD

Matsumoto, K. & Inoue, H., Mar 2014, In : Respiratory Investigation. 52, 2, p. 92-100 9 p.

Research output: Contribution to journalReview article

Virus Diseases
Chronic Obstructive Pulmonary Disease
Respiratory Syncytial Virus Infections
Asthma
Viruses
2012

Roles of viral infection in the pathogenesis of asthma and COPD

Matsumoto, K., Jan 15 2012, In : Respiration and Circulation. 60, 1, p. 69-77 9 p.

Research output: Contribution to journalReview article

Virus Diseases
Chronic Obstructive Pulmonary Disease
Asthma
2011

[Roles of costimulatory molecules in bronchial asthma].

Matsumoto, K. & Nakanishi, Y., Aug 1 2011, In : Fukuoka igaku zasshi = Hukuoka acta medica. 102, 8, p. 243-253 11 p.

Research output: Contribution to journalReview article

CD86 Antigens
CD80 Antigens
Asthma
2010
41 Citations (Scopus)

Lung cancer risk and genetic polymorphisms in DNA repair pathways: A meta-analysis

Kiyohara, C., Takayama, K. & Nakanishi, Y., Dec 1 2010, In : Journal of Nucleic Acids. 2010, 701760.

Research output: Contribution to journalReview article

Genetic Polymorphisms
Polymorphism
DNA Repair
Meta-Analysis
Lung Neoplasms

Molecular targeted therapy for COPD: Perspective

Matsumoto, K., Oct 1 2010, In : Respiration and Circulation. 58, 10, p. 995-1003 9 p.

Research output: Contribution to journalReview article

Molecular Targeted Therapy
Chronic Obstructive Pulmonary Disease
2007
12 Citations (Scopus)

Lung cancer susceptibility: Are we on our way to identifying a high-risk group?

Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Dec 1 2007, In : Future Oncology. 3, 6, p. 617-627 11 p.

Research output: Contribution to journalReview article

Genetic Polymorphisms
DNA Repair
Phase I Metabolic Detoxication
Lung Neoplasms
DNA Repair Enzymes

Major drug-induced lung diseases: adverse effects of anti-neoplastic agents in general

Nakanishi, Y., Harada, T. & Takayama, K., Jun 10 2007, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 96, 6, p. 1123-1128 6 p.

Research output: Contribution to journalReview article

Antineoplastic Antibiotics
Interstitial Lung Diseases
Bleomycin
Antineoplastic Agents
Lung Diseases
23 Citations (Scopus)

Role of endogenous inhibitors of cytokine signaling in allergic asthma

Inoue, H., Fukuyama, S., Matsumoto, K., Kubo, M. & Yoshimura, A., Jan 1 2007, In : Current Medicinal Chemistry. 14, 2, p. 181-189 9 p.

Research output: Contribution to journalReview article

Janus Kinases
Asthma
Interleukin-5
Extracellular Signal-Regulated MAP Kinases
Cytokines
30 Citations (Scopus)

The pathogenesis of COPD: Lessons learned from in vivo animal models

Fujita, M. & Nakanishi, Y., Feb 1 2007, In : Medical Science Monitor. 13, 2, p. RA19-RA24

Research output: Contribution to journalReview article

Chronic Obstructive Pulmonary Disease
Animal Models
Protease Inhibitors
Matrix Metalloproteinases
Morphogenesis
1 Citation (Scopus)

Two different functions of doxycycline which is both an antimicrobial agent and an immune modulator

Fujita, M. & Nakanishi, Y., Oct 1 2007, In : Anti-Infective Agents in Medicinal Chemistry. 6, 4, p. 222-227 6 p.

Research output: Contribution to journalReview article

Doxycycline
Anti-Infective Agents
Pneumonia
Legionella
Chlamydia
2006
152 Citations (Scopus)

Association of genetic polymorphisms in the base excision repair pathway with lung cancer risk: A meta-analysis

Kiyohara, C., Takayama, K. & Nakanishi, Y., Dec 1 2006, In : Lung Cancer. 54, 3, p. 267-283 17 p.

Research output: Contribution to journalReview article

Genetic Polymorphisms
DNA Repair
Meta-Analysis
Lung Neoplasms
Genes
68 Citations (Scopus)

EPHX1 polymorphisms and the risk of lung cancer: A HuGE review

Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Jan 1 2006, In : Epidemiology. 17, 1, p. 89-99 11 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Genotype
Exons
Odds Ratio
Genes
2005
22 Citations (Scopus)

Apoptosis signaling pathways in lung diseases.

Kuwano, K., Yoshimi, M., Maeyama, T., Hamada, N., Yamada, M. & Nakanishi, Y., Jan 2005, In : Medicinal chemistry. 1, 1, p. 49-56 8 p.

Research output: Contribution to journalReview article

Lung Diseases
Apoptosis
Death Domain Receptors
Caspase 8
Ligation
1 Citation (Scopus)

Clinical evaluation of pulmonary cryptococcosis: Including a case report of pulmonary cryptoccosis mimicking COP and a review of 17 cases

Ouchi, H., Fujita, M., Minami, T., Inoshima, I. & Nakanishi, Y., Mar 29 2005, In : Japanese Journal of Chest Diseases. 64, 2, p. 161-166 6 p.

Research output: Contribution to journalReview article

Cryptococcosis
Lung
Cryptogenic Organizing Pneumonia
Thorax
Tomography

Lymphocytes in bronchial asthma

Matsumoto, K., Inoue, H. & Nakanishi, Y., Feb 1 2005, In : Respiration and Circulation. 53, 2, p. 167-175 9 p.

Research output: Contribution to journalReview article

Asthma
Lymphocytes
86 Citations (Scopus)

NQO1, MPO, and the risk of lung cancer: A HuGE review

Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Sep 1 2005, In : Genetics in Medicine. 7, 7, p. 463-478 16 p.

Research output: Contribution to journalReview article

Peroxidase
Lung Neoplasms
Genotype
Carcinogens
Haplotypes
2004

ALI/ARDS and corticosteroids

Fujita, M. & Nakanishi, Y., Aug 1 2004, In : Respiration and Circulation. 52, 8, p. 775-780 6 p.

Research output: Contribution to journalReview article

Adrenal Cortex Hormones

Cytokines and Lung Diseases

Kuwano, K., Hagimoto, N., Inoue, H. & Nakanishi, Y., Mar 1 2004, In : Respiration and Circulation. 52, 3, p. 271-278 8 p.

Research output: Contribution to journalReview article

Lung Diseases
Cytokines

Does molecular targeted therapy change the treatment for lung cancer?

Nakanishi, Y., Sep 2004, In : Fukuoka igaku zasshi = Hukuoka acta medica. 95, 9, p. 205-209 5 p.

Research output: Contribution to journalReview article

Pathologic Neovascularization
Molecular Targeted Therapy
Quinazolines
erbB-1 Genes
Tumor Suppressor Protein p53
37 Citations (Scopus)

The role of apoptosis in pulmonary fibrosis

Kuwano, K., Hagimoto, N. & Nakanishi, Y., Jul 1 2004, In : Histology and histopathology. 19, 3, p. 867-881 15 p.

Research output: Contribution to journalReview article

Pulmonary Fibrosis
Lung Injury
Apoptosis
Immunosuppressive Agents
Connective Tissue
2003

EBM and molecular biology from the perspective of lung cancer due to tobacco smoking

Nakanishi, Y. & Takayama, K., Jan 1 2003, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 92, 6, p. 1089-1095 7 p.

Research output: Contribution to journalReview article

Benzopyrenes
Tobacco Use Cessation
Aryl Hydrocarbon Hydroxylases
Tumor Suppressor Protein p53
Cytochrome P-450 CYP1A1

Refractory Asthma and Airway Hyperresponsiveness

Komori, M., Inoue, H., Matsumoto, K., Fukuyama, S. & Nakanishi, Y., Dec 1 2003, In : Respiration and Circulation. 51, 12, p. 1203-1207 5 p.

Research output: Contribution to journalReview article

Asthma
2002

Management of paraneoplastic syndrome in lung cancer

Inoue, K. & Nakanishi, Y., Jan 1 2002, In : Nippon rinsho. Japanese journal of clinical medicine. 60 Suppl 5, p. 536-539 4 p.

Research output: Contribution to journalReview article

Inappropriate ADH Syndrome
Paraneoplastic Syndromes
Cushing Syndrome
Disseminated Intravascular Coagulation
Hypercalcemia

Molecular mechanism of lung carcinogenesis

Nakanishi, Y. & Hara, N., May 2002, In : Nippon rinsho. Japanese journal of clinical medicine. 60 Suppl 5, p. 58-62 5 p.

Research output: Contribution to journalReview article

mutations
smoking
lungs
mutation
benzopyrene

Why does smoking cause lung cancer?

Nakanishi, Y., Jan 2002, In : Fukuoka igaku zasshi = Hukuoka acta medica. 93, 1, p. 6-10 5 p.

Research output: Contribution to journalReview article

Benzopyrenes
Precancerous Conditions
DNA Adducts
p53 Genes
Genetic Predisposition to Disease
2001
1 Citation (Scopus)

Lung cancer

Hara, N. & Nakanishi, Y., Nov 2001, In : Nippon rinsho. Japanese journal of clinical medicine. 59 Suppl 7, p. 322-328 7 p.

Research output: Contribution to journalReview article

Sex Factors
Combined Modality Therapy
Environmental Pollution
Age Factors
Lung Neoplasms
2000
8 Citations (Scopus)

Epidemiology of lung cancer in Japan

Hara, N., Nakanishi, Y. & Izumi, M., May 2000, In : Nippon rinsho. Japanese journal of clinical medicine. 58, 5, p. 1005-1011 7 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Japan
Epidemiology
Early Detection of Cancer
Case-Control Studies

Gene therapy for lung cancer treatment

Takayama, K., Nakanishi, Y. & Hara, N., May 2000, In : Nippon rinsho. Japanese journal of clinical medicine. 58, 5, p. 1048-1052 5 p.

Research output: Contribution to journalReview article

Genetic Therapy
Lung Neoplasms
Neoplasms
Therapeutics
Suicide
2 Citations (Scopus)

Treatment of lung cancer--state of the art in 2000

Nakanishi, Y., Inoue, K. & Hara, N., Jul 2000, In : Gan to kagaku ryoho. Cancer & chemotherapy. 27, 8, p. 1247-1252 6 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Survival
Radiotherapy
Small Cell Lung Carcinoma
Drug Therapy
1997
2 Citations (Scopus)

Paraneoplastic syndrome

Nakanishi, Y., Takayama, K. & Hara, N., Oct 1997, In : Gan to kagaku ryoho. Cancer & chemotherapy. 24 Suppl 3, p. 445-450 6 p.

Research output: Contribution to journalReview article

Paraneoplastic Syndromes
Hyponatremia
pamidronate
Cushing Syndrome
Heparin
1994

Primary mediastinal germ cell tumors

Hara, N. & Nakanishi, Y., 1994, In : Ryōikibetsu shōkōgun shirīzu. 4, p. 421-424 4 p.

Research output: Contribution to journalReview article

Mediastinal Neoplasms
Germinoma
Germ Cell and Embryonal Neoplasms