Research Output 1985 2020

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2020

Automated approach for estimation of grade groups for prostate cancer based on histological image feature analysis

Hossain, A., Arimura, H., Kinoshita, F., Ninomiya, K., Watanabe, S., Imada, K., Koyanagi, R. & Oda, Y., Feb 1 2020, In : Prostate. 80, 3, p. 291-302 12 p.

Research output: Contribution to journalArticle

Neoplasm Grading
Prostatic Neoplasms
Observer Variation
Color
Research Ethics Committees

Computational analysis of morphological and molecular features in gastric cancer tissues

Yasuda, Y., Tokunaga, K., Koga, T., Sakamoto, C., Goldberg, I. G., Saitoh, N. & Nakao, M., Feb 3 2020, In : Cancer Medicine.

Research output: Contribution to journalArticle

Stomach Neoplasms
Neoplasms
Proteins
Hematoxylin
Eosine Yellowish-(YS)
2019

A novel assay for triglycerides using glycerol dehydrogenase and a water-soluble formazan dye, WST-8

Kawano, M., Hokazono, E., Osawa, S., Sato, S., Tateishi, T., Manabe, M., Matsui, H. & Kayamori, Y., Jul 1 2019, In : Annals of Clinical Biochemistry. 56, 4, p. 442-449 8 p.

Research output: Contribution to journalArticle

glycerol dehydrogenase
Formazans
Assays
Triglycerides
Coloring Agents
10 Citations (Scopus)

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Oshima, T., Niwa, Y., Kuwata, K., Srivastava, A., Hyoda, T., Tsuchiya, Y., Kumagai, M., Tsuyuguchi, M., Tamaru, T., Sugiyama, A., Ono, N., Zolboot, N., Aikawa, Y., Oishi, S., Nonami, A., Arai, F., Hagihara, S., Yamaguchi, J., Tama, F., Kunisaki, Y. & 6 others, Yagita, K., Ikeda, M., Kinoshita, T., Kay, S. A., Itami, K. & Hirota, T., Jan 23 2019, In : Science Advances. 5, 1, eaau9060.

Research output: Contribution to journalArticle

Open Access
Circadian Rhythm
Circadian Clocks
Phosphotransferases
Growth
Neoplasms
Sex Hormone-Binding Globulin
Genetic Polymorphisms
Androgens
Prostatic Neoplasms
Testosterone

Higher postictal parasympathetic activity following greater ictal heart rate increase in right- than left-sided seizures

Shimmura, M., Uehara, T., Ogata, K., Shigeto, H., Maeda, T., Sakata, A., Yamasaki, R. & Kira, J. I., Aug 2019, In : Epilepsy and Behavior. 97, p. 161-168 8 p.

Research output: Contribution to journalArticle

Seizures
Heart Rate
Stroke
ROC Curve
Partial Epilepsy

Nuclear co-expression of p21 and p27 induced effective cell-cycle arrest in T24 cells treated with BCG

Watanabe, S., Yamaguchi, S., Fujii, N., Eguchi, N., Katsuta, H., Sugishima, S., Iwasaka, T. & Kaku, T., Feb 15 2019, In : Cytotechnology. 71, 1, p. 219-229 11 p.

Research output: Contribution to journalArticle

Bacilli
Cell Cycle Checkpoints
Bacillus
Cells
Confocal Microscopy

Porosification of surface of platinum electrode by anisotropic etching

Terasawa, Y., Tashiro, H., Nakano, Y. & Ohta, J., Jan 1 2019, In : Sensors and Materials. 31, 6, p. 1957-1971 15 p.

Research output: Contribution to journalArticle

Open Access
Anisotropic etching
Platinum
platinum
etching
Electrodes
2 Citations (Scopus)

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J. I., Apr 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
2018
1 Citation (Scopus)

Characterization and application of a novel nicotinamide mononucleotide adenylyltransferase from Thermus thermophilus HB8

Konishi, K., Ueda, S., Kawano, M., Osawa, S., Tamura, T., Hokazono, E., Kayamori, Y. & Sakasegawa, S. I., Apr 2018, In : Journal of Bioscience and Bioengineering. 125, 4, p. 385-389 5 p.

Research output: Contribution to journalArticle

Nicotinamide-Nucleotide Adenylyltransferase
Nicotinamide Mononucleotide
Thermus thermophilus
NAD
Acids

Comparative study of sevoflurane and isoflurane anesthesia for the long-term safety evaluation of visual prosthesis with rabbits

Kuwabara, M., Tashiro, H., Nakano, Y., Terasawa, Y., Sawai, H. & Ohta, J., Jan 1 2018, In : Sensors and Materials. 30, 2, p. 287-297 11 p.

Research output: Contribution to journalArticle

anesthesia
Isoflurane
rabbits
Bioelectric potentials
safety
4 Citations (Scopus)

Decrease in the prevalence of extended-spectrum cephalosporin-resistant Salmonella following cessation of ceftiofur use by the Japanese poultry industry

Shigemura, H., Matsui, M., Sekizuka, T., Onozuka, D., Noda, T., Yamashita, A., Kuroda, M., Suzuki, S., Kimura, H., Fujimoto, S., Oishi, K., Sera, N., Inoshima, Y. & Murakami, K., Jun 2 2018, In : International Journal of Food Microbiology. 274, p. 45-51 7 p.

Research output: Contribution to journalArticle

ceftiofur
cephalosporins
poultry industry
chicken meat
Cephalosporins

Development of a simple indocyanine green measurement method using an automated biochemical analyser

Sato, Y., Seimiya, M., Yoshida, T., Sawabe, Y., Hokazono, E., Osawa, S. & Matsushita, K., Jul 1 2018, In : Annals of Clinical Biochemistry. 55, 4, p. 491-495 5 p.

Research output: Contribution to journalArticle

Indocyanine Green
Blood
Gastroenterology
Injections
Clinical laboratories

In vitro and in vivo long-term electrochemical properties of electrodes with femtosecond-laser-induced porosity for visual prostheses based on suprachoroidal transretinal stimulation

Tashiro, H., Kuwabara, M., Nakano, Y., Terasawa, Y., Osawa, K., Yoshimura, Y., Doi, H. & Ohta, J., Jan 1 2018, In : Sensors and Materials. 30, 2, p. 251-268 18 p.

Research output: Contribution to journalArticle

Prosthetics
Ultrashort pulses
Electrochemical properties
stimulation
Porosity

Lp-PLA2 activity assay methods

Yamaura, S., Sugimori, D. & Kayamori, Y., Apr 2018, In : Japanese Journal of Clinical Chemistry. 47, 2, p. 116-121 6 p.

Research output: Contribution to journalArticle

Assays
2 Citations (Scopus)

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

Gotoh, K., Morisaki, T., Setoyama, D., Sasaki, K., Yagi, M., Igami, K., Mizuguchi, S., Uchiumi, T., Fukui, Y. & Kang, D., Nov 13 2018, In : Cell Reports. 25, 7, p. 1800-1815.e4

Research output: Contribution to journalArticle

Metabolism
Dendritic Cells
Pyruvic Acid
Citric Acid
Oxidoreductases
3 Citations (Scopus)

Novel enzymatic method for assaying Lp-PLA2 in serum

Yamaura, S., Sakasegawa, S. I., Koguma, E., Ueda, S., Kayamori, Y., Sugimori, D. & Karasawa, K., Jun 2018, In : Clinica Chimica Acta. 481, p. 184-188 5 p.

Research output: Contribution to journalArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Serum
Phosphorylcholine
Platelet Activating Factor
Assays
3 Citations (Scopus)

Overexpression of mth1 and ogg1 proteins in ulcerative colitis-associated carcinogenesis

Kumagae, Y., Hirahashi, M., Takizawa, K., Yamamoto, H., Gushima, M., Esaki, M., Matsumoto, T., Nakamura, M., Kitazono, T. & Oda, Y., Aug 2018, In : Oncology Letters. 16, 2, p. 1765-1776 12 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Carcinogenesis
Neoplasms
Proteins
ras Proteins
2 Citations (Scopus)

Safety and efficacy of semichronic suprachoroidal transretinal stimulation with femtosecond laser-induced porosity and smooth-surface electrodes

Terasawa, Y., Tashiro, H., Nakano, Y. & Ohta, J., Jan 1 2018, In : Sensors and Materials. 30, 2, p. 235-249 15 p.

Research output: Contribution to journalArticle

Ultrashort pulses
stimulation
safety
Porosity
porosity

Serum starvation induces abnormal spindle location, RhoA delocalization, and extension of intercellular bridge with the midbody

Nishimura, K., Watanabe, S., Kaku, T. & Sugishima, S., Jan 1 2018, In : Bioscience, Biotechnology and Biochemistry. 82, 5, p. 821-826 6 p.

Research output: Contribution to journalArticle

Starvation
Mitosis
Cells
Serum
Cytokinesis
2 Citations (Scopus)

The Influence of Pre-Analytical Factors on the Analysis of Circulating MicroRNA

Shiotsu, H., Okada, K., Shibuta, T., Kobayashi, Y., Shirahama, S., Kuroki, C., Ueda, S., Ohkuma, M., Ikeda, K., Ando, Y., Matsui, H., Kayamori, Y. & Umemura, T., Jan 1 2018, In : MicroRNA (Shariqah, United Arab Emirates). 7, 3, p. 195-203 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Statistical Factor Analysis
Ribonucleases
Serum
Centrifugation
1 Citation (Scopus)

Useful laboratory markers for the diagnosis of bone marrow involvement by malignant lymphoma

Nishimura, K., Ota, R., Mikajiri, Y., Takahashi, K., Sugishima, S. & Eto, T., Feb 1 2018, In : International Journal of Laboratory Hematology. 40, 1, p. 34-40 7 p.

Research output: Contribution to journalArticle

Clinical Laboratory Techniques
Interleukin-2 Receptors
Lymphoma
Bone
Biomarkers
2017
9 Citations (Scopus)

Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies

Feichtinger, R. G., Oláhová, M., Kishita, Y., Garone, C., Kremer, L. S., Yagi, M., Uchiumi, T., Jourdain, A. A., Thompson, K., D'Souza, A. R., Kopajtich, R., Alston, C. L., Koch, J., Sperl, W., Mastantuono, E., Strom, T. M., Wortmann, S. B., Meitinger, T., Pierre, G., Chinnery, P. F. & 19 others, Chrzanowska-Lightowlers, Z. M., Lightowlers, R. N., DiMauro, S., Calvo, S. E., Mootha, V. K., Moggio, M., Sciacco, M., Comi, G. P., Ronchi, D., Murayama, K., Ohtake, A., Rebelo-Guiomar, P., Kohda, M., Kang, D., Mayr, J. A., Taylor, R. W., Okazaki, Y., Minczuk, M. & Prokisch, H., Oct 5 2017, In : American journal of human genetics. 101, 4, p. 525-538 14 p.

Research output: Contribution to journalArticle

Chronic Progressive External Ophthalmoplegia
Oxidative Phosphorylation
Muscular Diseases
Electron Transport
Cardiomyopathies
6 Citations (Scopus)

Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses

Saito, T., Uchiumi, T., Yagi, M., Amamoto, R., Setoyama, D., Matsushima, Y. & Kang, D., Aug 1 2017, In : Cardiovascular research. 113, 10, p. 1173-1185 13 p.

Research output: Contribution to journalArticle

Takotsubo Cardiomyopathy
Cardiac Myocytes
Mitochondria
Mitochondrial Proteins
Sirolimus
8 Citations (Scopus)

Characteristics of primary and metachronous gastric cancers discovered after helicobacter pylori eradication: A multicenter propensity score-matched study

Maehata, Y., Nakamura, S., Esaki, M., Ikeda, F., Moriyama, T., Hida, R., Washio, E., Umeno, J., Hirahashi, M., Kitazono, T. & Matsumoto, T., Sep 2017, In : Gut and Liver. 11, 5, p. 628-634 7 p.

Research output: Contribution to journalArticle

Propensity Score
Helicobacter pylori
Stomach Neoplasms
Neoplasms
Helicobacter Infections

Diffuse gastric metastases from salivary duct carcinoma

Maehata, Y., Hori, Y., Hirahashi, M., Yamamoto, H. & Esaki, M., Nov 2017, In : Gastrointestinal endoscopy. 86, 5, p. 916-917 2 p.

Research output: Contribution to journalArticle

Salivary Ducts
Stomach
Neoplasm Metastasis
Carcinoma
4 Citations (Scopus)

Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography

Tsurumaru, D., Miyasaka, M., Muraki, T., Asayama, Y., Nishie, A., Oki, E., Hirahashi, M., Hida, T. & Honda, H., Jun 1 2017, In : Japanese Journal of Radiology. 35, 6, p. 289-295 7 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Tomography
Contrast Media
Stomach
Injections
10 Citations (Scopus)
Endoplasmic Reticulum Stress
Neoplastic Stem Cells
Doxycycline
Stem Cells
Apoptosis
3 Citations (Scopus)
Protein Biosynthesis
Drosophila
Peptide Hydrolases
Unfolded Protein Response
Mitochondrial Genes
12 Citations (Scopus)

Duodenal Neoplasms of Gastric Phenotype: An Immunohistochemical and Genetic Study with a Practical Approach to the Classification

Hida, R., Yamamoto, H., Hirahashi, M., Kumagai, R., Nishiyama, K., Gi, T., Esaki, M., Kitazono, T. & Oda, Y., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 3, p. 343-353 11 p.

Research output: Contribution to journalArticle

Duodenal Neoplasms
Adenoma
Stomach
Phenotype
Adenocarcinoma
2 Citations (Scopus)

Gastric neuroendocrine tumor with hypergastrinemia

Yamaguchi, E., Iwasa, T., Ihara, E., Tomita, Y., Aso, A., Oki, E., Nakano, K., Hirahashi, M. & Nakamura, K., Jan 1 2017, In : Journal of Japanese Society of Gastroenterology. 114, 2, p. 248-255 8 p.

Research output: Contribution to journalArticle

Atrophic Gastritis
Neuroendocrine Tumors
Stomach
Helicobacter pylori
Gastrinoma

Guideline for standardization of external quality assessment and proficiency testing in the field of clinical chemistry

Hamasaki, N., Hosogaya, S., Ikeda, K., Ueda, S., Osawa, S., Kayamori, Y., Kuwa, K., Sato, S., Shinohara, K., Sueyoshi, S., Sekiguchi, M., Takagi, Y., Nagamine, Y., Nobori, T., Miyake, K. & Yamamoto, Y., Jul 2017, In : Japanese Journal of Clinical Chemistry. 46, 3, p. 238-245 8 p.

Research output: Contribution to journalArticle

Clinical Chemistry
Standardization
Guidelines
Testing
Accreditation
1 Citation (Scopus)

Long-term analysis of in vivo characteristics of recording electrode using electrochemical impedance spectroscopy

Kuwabara, M., Tashiro, H., Terasawa, Y., Nakano, Y., Yoshimura, Y., Osawa, K., Noda, T., Tokuda, T. & Ohta, J., Jan 1 2017, In : Sensors and Materials. 29, 12, p. 1689-1702 14 p.

Research output: Contribution to journalArticle

Bioelectric potentials
Electrochemical impedance spectroscopy
recording
impedance
Electrodes
2 Citations (Scopus)
Leukoencephalopathies
Oligodendroglia
Axons
Electron Transport
Central Nervous System
2 Citations (Scopus)
Campylobacter
Gene Targeting
Restriction Fragment Length Polymorphisms
Polymerase Chain Reaction
Fetus
4 Citations (Scopus)

p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

Sasaki, K., Gotoh, K., Miake, S., Setoyama, D., Yagi, M., Igami, K., Uchiumi, T. & Kang, D., Jun 2017, In : EBioMedicine. 20, p. 161-172 12 p.

Research output: Contribution to journalArticle

Endotoxins
Lipopolysaccharides
Shock
Interleukin-6
Fibroblasts
1 Citation (Scopus)

Pulsed-field profile diversities of salmonella enteritidis, s. Infantis, and s. corvallis in Japan

Murakami, K., Noda, T., Onozuka, D., Kimura, H. & Fujimoto, S., 2017, In : Italian Journal of Food Safety. 6, 3, p. 138-144 7 p., 6808.

Research output: Contribution to journalArticle

Salmonella enteritidis
Salmonella Enteritidis
Chickens
Salmonella
Japan

Pulsed-field profile diversities of Salmonella Enteritidis, S. Infantis, and S. Corvallis in Japan

Murakami, K., Noda, T., Onozuka, D., Kimura, H. & Fujimoto, S., Aug 16 2017, In : Italian Journal of Food Safety. 6, 3, p. 6808

Research output: Contribution to journalArticle

Salmonella enteritidis
Salmonella Enteritidis
Chickens
Japan
Salmonella

Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks

Murakami, K., Maeda-Mitani, E., Onozuka, D., Noda, T., Sera, N., Kimura, H., Fujimoto, S. & Murakami, S., 2017, In : Irish Veterinary Journal. 70, p. 27

Research output: Contribution to journalArticle

Salmonella Infantis
Salmonella Typhimurium
Salmonella
oral administration
Oral Administration
2 Citations (Scopus)

Sinusoidal electrical pulse more efficiently evokes retinal excitation than rectangular electrical pulse in retinal prostheses

Nakano, Y., Terasawa, Y., Kanda, H., Tashiro, H., Osawa, K., Miyoshi, T., Sawai, H. & Fujikado, T., Jan 1 2017, In : Sensors and Materials. 29, 12, p. 1667-1677 11 p.

Research output: Contribution to journalArticle

Prosthetics
pulses
excitation
phosphene
Electrodes
4 Citations (Scopus)

Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese

Mine, K., Hirakawa, K., Kondo, S., Minami, M., Okada, A., Tsutsu, N., Yokogawa, Y., Hibio, Y., Kojima, F., Fujimoto, S., Kurisaki, H., Anzai, K., Yoshikai, Y. & Nagafuchi, S., 2017, (Accepted/In press) In : EBioMedicine. 23, p. 46-51 6 p.

Research output: Contribution to journalArticle

TYK2 Kinase
Medical problems
Type 1 Diabetes Mellitus
Immunoglobulin E
Antibodies

Systemic chemotherapy with pronounced efficacy and neutropenia in a granulocyte-colony stimulating factor-producingadvanced gastric neuroendocrine carcinoma

Tsuruta, N., Takayoshi, K., Arita, S., Aikawa, T., Ariyama, H., Kusaba, H., Ohuchida, K., Nagai, E., Kohashi, K., Hirahashi, M., Inadomi, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Jan 1 2017, In : Oncology Letters. 14, 2, p. 1500-1504 5 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Granulocyte Colony-Stimulating Factor
Neutropenia
Stomach
Drug Therapy
2016

A case of A 3 - mm ileal neuroendocrine tumor with distant lymph node metastasis

Tokumaru, K., Ihara, E., Iwasa, T., Itaba, S., Andou, Y., Oki, E., Takizawa, N., Hirahashi, M., Oda, Y. & Nakamura, K., Jan 2016, In : GASTROENTEROLOGICAL ENDOSCOPY. 58, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Tumors
Lymph Nodes
Neoplasm Metastasis
Lymph Node Excision
Ileum
1 Citation (Scopus)

A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride

Shimmura, M., Kawamura, N., Tateishi, T., Shigeto, H., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 2, p. 108-111 4 p.

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Brain Hypoxia
Clonidine
Decerebrate State
Tachypnea

A case of primary central nervous system vasculitis diagnosed by second brain biopsy and treated successfully

Mizuno, Y., Shigeto, H., Yamada, T., Maeda, N., Suzuki, S. O. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

Central Nervous System Vasculitis
Biopsy
Brain
Frontal Lobe
Diplopia
3 Citations (Scopus)
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke
Occipital Lobe
9 Citations (Scopus)

Adjusting the 17b-etradiol-to-androgen ratio ameliorates diabetic nephropathy

Inada, A., Inada, O., Fujii, N. L., Nagafuchi, S., Katsuta, H., Yasunami, Y., Matsubara, T., Arai, H., Fukatsu, A. & Nabeshima, Y. I., Jan 1 2016, In : Journal of the American Society of Nephrology. 27, 10, p. 3035-3050 16 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Androgens
Transgenic Mice
Albuminuria
Hyperglycemia
3 Citations (Scopus)

Binucleated HeLa cells are formed by cytokinesis failure in starvation and keep the potential of proliferation

Nishimura, K., Watanabe, S., Hayashida, R., Sugishima, S., Iwasaka, T. & Kaku, T., Aug 1 2016, In : Cytotechnology. 68, 4, p. 1123-1130 8 p.

Research output: Contribution to journalArticle

Cytokinesis
Starvation
HeLa Cells
Tumors
Tissue culture
4 Citations (Scopus)

Conversion to neuroendocrine carcinoma from squamous cell carcinoma of the esophagus after definitive chemoradiotherapy

Morita, M., Saeki, H., Nakaji, Y., Zaitsu, Y., Hirahashi, M., Ohguri, T., Oki, E., Toh, Y., Oda, Y. & Maehara, Y., Aug 2016, In : Anticancer research. 36, 8, p. 4045-4049 5 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Chemoradiotherapy
Esophagus
Squamous Cell Carcinoma
Neuroendocrine Tumors

Dermatomyositis complicated with asymmetric peripheral neuritis on exacerbation: A case report and literature review

Irie, T., Shigeto, H., Koge, J., Yamaguchi, H., Murai, H. & Kira, J. I., Nov 1 2016, In : Clinical and Experimental Neuroimmunology. 7, 4, p. 373-380 8 p.

Research output: Contribution to journalArticle

Neuritis
Dermatomyositis
Mononeuropathies
Peroneal Nerve
Muscle Weakness