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2020

Activation of death receptor, DR5 and mitochondria-mediated apoptosis by a 3,4,5-trimethoxybenzyloxy derivative in wild-type and p53 mutant colorectal cancer cell lines

Chan, Z. C. K., Leong, K. H., Kareem, H. S., Norazit, A., Noor, S. M. & Ariffin, A., Mar 1 2020, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 393, 3, p. 405-417 13 p.

Research output: Contribution to journalArticle

Amino Acid Schiff Base Bearing Benzophenone Imine As a Platform for Highly Congested Unnatural α-Amino Acid Synthesis

Matsumoto, Y., Sawamura, J., Murata, Y., Nishikata, T., Yazaki, R. & Ohshima, T., Jan 1 2020, (Accepted/In press) In : Journal of the American Chemical Society.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access

An estimated quantitative lateral flow immunoassay for determination of artesunate using monoclonal antibody

Kitisripanya, T., Sermpradit, W., Sakamoto, S., Tanaka, H. & Putalun, W., Feb 1 2020, In : Biomedical Chromatography. 34, 2, e4718.

Research output: Contribution to journalArticle

Open Access

Applicability of the Øie-Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase

Yahata, M., Ishii, Y., Nakagawa, T., Watanabe, T. & Miyawaki, I., Apr 1 2020, In : Biopharmaceutics and Drug Disposition. 41, 4-5, p. 151-165 15 p.

Research output: Contribution to journalArticle

Bidirectional regulation between NDRG1 and GSK3β controls tumor growth and is targeted by differentiation inducing factor-1 in glioblastoma

Ito, H., Watari, K., Shibata, T., Miyamoto, T., Murakami, Y., Nakahara, Y., Izumi, H., Wakimoto, H., Kuwano, M., Abe, T. & Ono, M., Jan 15 2020, In : Cancer Research. 80, 2, p. 234-248 15 p.

Research output: Contribution to journalArticle

Catalytic Aerobic Cross-Dehydrogenative Coupling of Azlactones en Route to α,α-Disubstituted α-Amino Acids

Tsuji, T., Tanaka, T., Tanaka, T., Yazaki, R. & Ohshima, T., Jun 5 2020, In : Organic letters. 22, 11, p. 4164-4170 7 p.

Research output: Contribution to journalArticle

Characterization and Water-Proton Longitudinal Relaxivities of Liposome-Type Radical Nanoparticles Prepared via a Supramolecular Approach

Shiraishi, R., Matsumoto, S., Fuchi, Y., Naganuma, T., Yoshihara, D., Usui, K., Yamada, K. I. & Karasawa, S., May 19 2020, In : Langmuir. 36, 19, p. 5280-5286 7 p.

Research output: Contribution to journalArticle

Characterization of CD44-positive Cancer Stem-like Cells in COLO 201 Cells

Okuyama, H., Nogami, W., Sato, Y., Yoshida, H., Tona, Y. & Tanaka, Y., Jan 1 2020, In : Anticancer research. 40, 1, p. 169-176 8 p.

Research output: Contribution to journalArticle

Characterization of Powder- and Tablet Properties of Different Direct Compaction Grades of Mannitol Using a Kohonen Self-organizing Map and a Lasso Regression Model

Kosugi, A., Leong, K. H., Tsuji, H., Hayashi, Y., Kumada, S., Okada, K. & Onuki, Y., Jan 1 2020, (Accepted/In press) In : Journal of Pharmaceutical Sciences.

Research output: Contribution to journalArticle

Characterization of α-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor

Yamada, H., Mizuno, S., Honda, S., Takahashi, D. & Sakane, F., Jun 1 2020, In : FEBS Journal. 287, 11, p. 2212-2234 23 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1 Citation (Scopus)

Circadian expression of Glycoprotein 2 (Gp2) gene is controlled by a molecular clock in mouse Peyer's patches

Kusunose, N., Tsuruta, A., Hamamura, K., Tsurudome, Y., Yoshida, Y., Akamine, T., Matsunaga, N., Koyanagi, S. & Ohdo, S., Apr 1 2020, In : Genes to Cells. 25, 4, p. 270-278 9 p.

Research output: Contribution to journalArticle

Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: Structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding

Nagata, K., Okada, A., Ohtsuka, J., Ohkuri, T., Akama, Y., Sakiyama, Y., Miyazaki, E., Horita, S., Katayama, T., Ueda, T. & Tanokura, M., Jan 1 2020, In : Journal of biochemistry. 167, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Open Access

C-terminal cysteine PEGylation of adalimumab fab with an engineered interchain SS bond

Nakamura, H., Anraku, M., Oda-Ueda, N., Ueda, T. & Ohkuri, T., Mar 1 2020, In : Biological and Pharmaceutical Bulletin. 43, 3, p. 418-423 6 p.

Research output: Contribution to journalArticle

Open Access

Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil

Fujimoto, Y., Nakanishi, R., Nukatsuka, M., Matsuoka, K., Ando, K., Wakasa, T., Kitao, H., Oki, E., Maehara, Y. & Mori, M., Jun 1 2020, In : Cancer chemotherapy and pharmacology. 85, 6, p. 1029-1038 10 p.

Research output: Contribution to journalArticle

Development of novel C-nucleoside analogues for the formation of antiparallel-type triplex DNA with duplex DNA that includes TA and dUA base pairs

Taniguchi, Y., Magata, Y., Osuki, T., Notomi, R., Wang, L., Okamura, H. & Sasaki, S., Apr 21 2020, In : Organic and Biomolecular Chemistry. 18, 15, p. 2845-2851 7 p.

Research output: Contribution to journalArticle

Effects of Diluent Volume and Administration Time on the Incidence of Anaphylaxis Following Docetaxel Therapy in Breast Cancer

Ishida, S., Masuguchi, K., Kawashiri, T., Tsuji, T., Watanabe, H., Akiyoshi, S., Kubo, M., Masuda, S. & Egashira, N., 2020, In : Biological & pharmaceutical bulletin. 43, 4, p. 663-668 6 p.

Research output: Contribution to journalArticle

Fluorescence detection of deoxyadenosine in Cordyceps spp. By indicator displacement assay

Dewantari, A. A., Yongwattana, N., Payongsri, P., Seemakhan, S., Borwornpinyo, S., Ojida, A. & Wongkongkatep, J., May 2020, In : Molecules. 25, 9, 2045.

Research output: Contribution to journalArticle

Open Access

Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells

Uchinomiya, S., Matsunaga, N., Kamoda, K., Kawagoe, R., Tsuruta, A., Ohdo, S. & Ojida, A., Mar 11 2020, In : Chemical Communications. 56, 20, p. 3023-3026 4 p.

Research output: Contribution to journalArticle

Fluorescence Differentiation of ATP-related Multiple Enzymatic Activities in Synovial Fluid as a Marker of Calcium Pyrophosphate Deposition Disease using Kyoto Green

Yongwattana, N., Mekjinda, N., Tawonsawatruk, T., Hamachi, I., Ojida, A. & Wongkongkatep, J., Mar 2 2020, In : Molecules. 25, 5, 1116.

Research output: Contribution to journalArticle

Open Access

Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1

Igarashi, R., Yamashita, S-I., Yamashita, T., Inoue, K., Fukuda, T., Fukuchi, T. & Kanki, T., Jan 30 2020, In : Scientific reports. 10, 1, p. 1465

Research output: Contribution to journalArticle

Genetic ablation of aldehyde reductase (Akr1a) augments exercise endurance in mice via activation of the PGC-1α-involved pathway

Takahashi, M., Homma, T., Yamada, K. I., Miyata, S., Nakajima, O. & Fujii, J., May 15 2020, In : Life Sciences. 249, 117501.

Research output: Contribution to journalArticle

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

Fujiyama, H., Tsuji, T., Hironaka, K., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2020, In : Journal of biochemistry. 167, 1, p. 15-24 10 p.

Research output: Contribution to journalArticle

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

Miyauchi, Y., Kurita, A., Yamashita, R., Takamatsu, T., Ikushiro, S., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., Apr 30 2020, In : Biochemical and Biophysical Research Communications. 525, 2, p. 348-353 6 p.

Research output: Contribution to journalArticle

Open Access

Isolation of new secondary metabolites from gorgonian soft coral Heteroxenia fuscescens collected from Red Sea

Abdelkarem, F. M., Desoky, E. E. K., Nafady, A. M., Allam, A. E., Mahdy, A., Nagata, M., Miyamoto, T. & Shimizu, K., Apr 2020, In : Phytochemistry Letters. 36, p. 156-161 6 p.

Research output: Contribution to journalArticle

Leukotriene B4 receptor 1 exacerbates inflammation following myocardial infarction

Horii, Y., Nakaya, M., Ohara, H., Nishihara, H., Watari, K., Nagasaka, A., Nakaya, T., Sugiura, Y., Okuno, T., Koga, T., Tanaka, A., Yokomizo, T. & Kurose, H., Jun 1 2020, In : FASEB Journal. 34, 6, p. 8749-8763 15 p.

Research output: Contribution to journalArticle

Open Access

Masking Phosphate with Rare-Earth Elements Enables Selective Detection of Arsenate by Dipycolylamine-ZnII Chemosensor

Mekjinda, N., Phunnarungsi, S., Ruangpornvisuti, V., Ritchie, R. J., Hamachi, I., Ojida, A. & Wongkongkatep, J., Dec 1 2020, In : Scientific reports. 10, 1, 2656.

Research output: Contribution to journalArticle

Open Access

Mechanistic studies of nickel(II)-catalyzed direct alcoholysis of 8-aminoquinoline amides

Morimoto, H., Akkad, W., Deguchi, T. & Ohshima, T., Jan 1 2020, In : Heterocycles. 101, 2, p. 471-485 15 p.

Research output: Contribution to journalArticle

Open Access

Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity

Tadokoro, T., Ikeda, M., Ide, T., Deguchi, H., Ikeda, S., Okabe, K., Ishikita, A., Matsushima, S., Koumura, T., Yamada, K. I., Imai, H. & Tsutsui, H., May 7 2020, In : JCI Insight. 5, 9, e132747.

Research output: Contribution to journalArticle

Open Access

Molecular cloning and characterization of type Ш polyketide synthase from Plumbago zeylanica

Sakamoto, S., Morita, Y., Yusakul, G., Putalun, W., Tanaka, H. & Morimoto, S., Jan 1 2020, (Accepted/In press) In : Journal of Asian Natural Products Research.

Research output: Contribution to journalArticle

NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells

Watari, K., Shibata, T., Fujita, H., Shinoda, A., Murakami, Y., Abe, H., Kawahara, A., Ito, H., Akiba, J., Yoshida, S., Kuwano, M. & Ono, M., Dec 1 2020, In : Communications Biology. 3, 1, 107.

Research output: Contribution to journalArticle

Open Access

Neuroprotective effect of alogliptin on oxaliplatin-induced peripheral neuropathy in vivo and in vitro

Shigematsu, N., Kawashiri, T., Kobayashi, D., Shimizu, S., Mine, K., Hiromoto, S., Uchida, M., Egashira, N. & Shimazoe, T., Apr 21 2020, In : Scientific reports. 10, 1, p. 6734

Research output: Contribution to journalArticle

Open Access

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate

Aoki, Y., Taniguchi, Y., Matsumoto, M., Matsumoto, M., Ohno, M., Masumura, K., Sasaki, S., Tsuzuki, T., Yamamoto, M. & Nohmi, T., Feb 1 2020, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 850-851, 503136.

Research output: Contribution to journalArticle

Palmitic acid- and/or palmitoleic acid-containing phosphatidic acids are generated by diacylglycerol kinase α in starved Jurkat T cells

Murakami, Y., Murakami, C., Hoshino, F., Lu, Q., Akiyama, R., Yamaki, A., Takahashi, D. & Sakane, F., May 14 2020, In : Biochemical and Biophysical Research Communications. 525, 4, p. 1054-1060 7 p.

Research output: Contribution to journalArticle

Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells

Yokobori, K., Miyauchi, Y., Williams, J. G. & Negishi, M., Apr 2020, In : Bioscience reports. 40, 4, BSR20200498.

Research output: Contribution to journalArticle

Open Access

Phytochemical analysis of two Weigela florida cultivars, “Pink Poppet” and “Jean's Gold”

Nguyen, D. H., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Bellaye, P. S., Collin, B., Chambin, O. & Lacaille-Dubois, M. A., Jun 2020, In : Phytochemistry Letters. 37, p. 85-89 5 p.

Research output: Contribution to journalArticle

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

Ydens, E., Amann, L., Asselbergh, B., Scott, C. L., Martens, L., Sichien, D., Mossad, O., Blank, T., De Prijck, S., Low, D., Masuda, T., Saeys, Y., Timmerman, V., Stumm, R., Ginhoux, F., Prinz, M., Janssens, S. & Guilliams, M., May 1 2020, In : Nature Neuroscience. 23, 5, p. 676-689 14 p.

Research output: Contribution to journalArticle

R409K mutation prevents acid-induced aggregation of human IgG4

Namisaki, H., Saito, S., Hiraishi, K., Haba, T., Tanaka, Y., Yoshida, H., Iida, S. & Takahashi, N., Jan 1 2020, In : PloS one. 15, 3, e0229027.

Research output: Contribution to journalArticle

Open Access

Radioiodinated Nitroxide Derivative for the Detection of Lipid Radicals

Yamasaki, T., Azuma, R., Sano, K., Munekane, M., Matsuoka, Y., Yamada, K. I. & Mukai, T., Jan 9 2020, In : ACS Medicinal Chemistry Letters. 11, 1, p. 45-48 4 p.

Research output: Contribution to journalArticle

Reaction targets of antioxidants in azo-initiator or lipid hydroperoxide induced lipid peroxidation

Saito, K., Matsuoka, Y. & Yamada, K. I., Jan 1 2020, (Accepted/In press) In : Free Radical Research.

Research output: Contribution to journalArticle

Rhodium(I)/Chiral Diene-Catalyzed Enantioselective Addition of Boronic Acids to N-Unsubstituted Isatin-Derived Ketimines

Yonesaki, R., Kusagawa, I., Morimoto, H., Hayashi, T. & Ohshima, T., Jan 1 2020, (Accepted/In press) In : Chemistry - An Asian Journal. 15, 4, p. 499-502 4 p.

Research output: Contribution to journalArticle

Scandium(III) Triflate Catalyzed Direct Synthesis of N-Unprotected Ketimines

Kondo, Y., Kadota, T., Hirazawa, Y., Morisaki, K., Morimoto, H. & Ohshima, T., Jan 3 2020, In : Organic Letters. 22, 1, p. 120-125 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor

Koga, K., Yamagata, R., Kohno, K., Yamane, T., Shiratori-Hayashi, M., Kohro, Y., Tozaki-Saitoh, H. & Tsuda, M., Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 183-191.e10

Research output: Contribution to journalArticle

Targeting Phosphorylation of Y-Box-Binding Protein YBX1 by TAS0612 and Everolimus in Overcoming Antiestrogen Resistance

Shibata, T., Watari, K., Kawahara, A., Sudo, T., Hattori, S., Murakami, Y., Izumi, H., Itou, J., Toi, M., Akiba, J., Akagi, Y., Tanaka, M., Kuwano, M. & Ono, M., Mar 1 2020, In : Molecular cancer therapeutics. 19, 3, p. 882-894 13 p.

Research output: Contribution to journalArticle