Faculty of Pharmaceutical Sciences

Research Output 1986 2019

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2007
21 Citations (Scopus)

Development of immunostimulatory virotherapy using non-transmissible Sendai virus-activated dendritic cells

Yoneyama, Y., Ueda, Y., Akutsu, Y., Matsunaga, A., Shimada, H., Kato, T., Kubota-Akizawa, M., Okano, S., Shibata, S., Sueishi, K., Hasegawa, M., Ochiai, T. & Yonemitsu, Y., Mar 30 2007, In : Biochemical and Biophysical Research Communications. 355, 1, p. 129-135 7 p.

Research output: Contribution to journalArticle

Sendai virus
Viruses
Dendritic Cells
Immunotherapy
Tumors
133 Citations (Scopus)

Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line

Ogino, A., Kitao, H., Hirano, S., Uchida, A., Ishiai, M., Kozuki, T., Takigawa, N., Takata, M., Kiura, K. & Tanimoto, M., Aug 15 2007, In : Cancer Research. 67, 16, p. 7807-7814 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Cell Line
Mutation
gefitinib
9 Citations (Scopus)

Impact of deletion of envelope-related genes of recombinant Sendai viruses on immune responses following pulmonary gene transfer of neonatal mice

Tanaka, S., Yonemitsu, Y., Yoshida, K., Okano, S., Kondo, H., Inoue, M., Hasegawa, M., Masumoto, K., Suita, S., Taguchi, T. & Sueishi, K., Jul 1 2007, In : Gene Therapy. 14, 13, p. 1017-1028 12 p.

Research output: Contribution to journalArticle

Sendai virus
Lung
Genes
Infant, Newborn, Diseases
Inbred ICR Mouse
92 Citations (Scopus)

Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis

Kimura, Y. N., Watari, K., Fotovati, A., Hosoi, F., Yasumoto, K., Izumi, H., Kohno, K., Umezawa, K., Iguchi, H., Shirouzu, K., Takamori, S., Kuwano, M. & Ono, M., Dec 1 2007, In : Cancer Science. 98, 12, p. 2009-2018 10 p.

Research output: Contribution to journalArticle

Interleukin-1
Macrophages
Growth
Neoplasms
Chemokine CCL2
67 Citations (Scopus)

Inhibition of progression and stabilization of plaques by postnatal interferon-γ function blocking in ApoE-knockout mice

Koga, M., Kai, H., Yasukawa, H., Yamamoto, T., Kawai, Y., Kato, S., Kusaba, K., Kai, M., Egashira, K., Kataoka, Y. & Imaizumi, T., Aug 1 2007, In : Circulation research. 101, 4, p. 348-356 9 p.

Research output: Contribution to journalArticle

Interferon Receptors
Apolipoproteins E
Knockout Mice
Interferons
Atherosclerotic Plaques
13 Citations (Scopus)

In vivo reduction of the nuclear factor-κB activity using synthetic cis-element decoy oligonucleotides suppresses intimal hyperplasia in the injured carotid arteries in rabbits

Takeuchi, K., Itoh, H., Yonemitsu, Y., matsumoto, T., Kume, M., Komori, K. & Maehara, Y., Jul 1 2007, In : Surgery today. 37, 7, p. 575-583 9 p.

Research output: Contribution to journalArticle

Tunica Intima
Sendai virus
Carotid Arteries
Liposomes
Oligonucleotides
93 Citations (Scopus)

Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling

Taniguchi, K., Kohno, R. I., Ayada, T., Kato, R., Ichiyama, K., Morisada, T., Oike, Y., Yonemitsu, Y., Maehara, Y. & Yoshimura, A., Jun 1 2007, In : Molecular and Cellular Biology. 27, 12, p. 4541-4550 10 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor-3
Lymphangiogenesis
Lymphatic Vessels
Vascular Endothelial Growth Factor C
Blood Vessels
2006
8 Citations (Scopus)

A free radical scavenger but not FGF-2-mediated angiogenic therapy rescues myonephropathic metabolic syndrome in severe hindlimb ischemia

Kaneko, K., Yonemitsu, Y., Fujii, T., Onimaru, M., Jin, C. H., Inoue, M., Hasegawa, M., Onohara, T., Maehara, Y. & Sueishi, K., Apr 1 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 4

Research output: Contribution to journalArticle

Free Radical Scavengers
Fibroblast Growth Factor 2
Hindlimb
Ischemia
Reperfusion
42 Citations (Scopus)

Angiotensin II type 1 receptor blockade attenuates in-stent restenosis by inhibiting inflammation and progenitor cells

ohtani, K., Egashira, K., Ihara, Y., Nakano, K., Funakoshi, K., Zhao, G., Sata, M. & Sunagawa, K., Oct 1 2006, In : Hypertension. 48, 4, p. 664-670 7 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Stents
Neointima
Stem Cells
Inflammation
99 Citations (Scopus)

Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivo

Schepers, A., Eefting, D., Bonta, P. I., Grimbergen, J. M., De Vries, M. R., Van Weel, V., De Vries, C. J., Egashira, K., Van Bockel, J. H. & Quax, P. H. A., Sep 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 9, p. 2063-2069 7 p.

Research output: Contribution to journalArticle

Tunica Intima
Vascular Smooth Muscle
Genetic Therapy
Smooth Muscle Myocytes
Hyperplasia
69 Citations (Scopus)

Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis

Hara, A., Wada, T., Furuichi, K., Sakai, N., Kawachi, H., Shimizu, F., Shibuya, M., Matsushima, K., Yokoyama, H., Egashira, K. & Kaneko, S., Jan 1 2006, In : Kidney International. 69, 11, p. 1986-1995 10 p.

Research output: Contribution to journalArticle

Glomerulonephritis
Vascular Endothelial Growth Factor Receptor-1
Proteinuria
Vascular Endothelial Growth Factor A
Kidney
15 Citations (Scopus)

Critical roles of memory T cells and antidonor immunoglobulin in rejection of allogeneic bone marrow cells in sensitized recipient mice

Nagata, S., Okano, S., Yonemitsu, Y., Nakagawa, K., Tomita, Y., Yoshikai, Y., Shimada, M., Maehara, Y. & Sueishi, K., Sep 1 2006, In : Transplantation. 82, 5, p. 689-698 10 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Immunoglobulins
T-Lymphocytes
Inbred C3H Mouse
Immunologic Memory
46 Citations (Scopus)

Diabetic microangiopathy in ischemic limb is a disease of disturbance of the platelet-derived growth factor-BB/protein kinase C axis but not of impaired expression of angiogenic factors

Tanii, M., Yonemitsu, Y., Fujii, T., Shikada, Y., Kohno, R. I., Onimaru, M., Okano, S., Inoue, M., Hasegawa, M., Onohara, T., Maehara, Y. & Sueishi, K., Jan 1 2006, In : Circulation research. 98, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Diabetic Angiopathies
Angiogenesis Inducing Agents
Protein Kinase C
Extremities
Streptozocin
57 Citations (Scopus)

Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-β gene

Shibata, S., Okano, S., Yonemitsu, Y., Onimaru, M., Sata, S., Nagata-Takeshita, H., Inoue, M., Zhu, T., Hasegawa, M., Moroi, Y., Furue, M. & Sueishi, K., Sep 15 2006, In : Journal of Immunology. 177, 6, p. 3564-3576 13 p.

Research output: Contribution to journalArticle

Sendai virus
Dendritic Cells
Immunity
Genes
Immunotherapy
57 Citations (Scopus)

Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: Critical role of the inflammatory/arteriogenic pathway

Fujii, T., Yonemitsu, Y., Onimaru, M., Tanii, M., Nakano, T., Egashira, K., Takehara, T., Inoue, M., Hasegawa, M., Kuwano, H. & Sueishi, K., Nov 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 11, p. 2483-2489 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Fibroblast Growth Factor 2
Vascular Endothelial Growth Factor A
Therapeutics
CCR2 Receptors
45 Citations (Scopus)

Stent-based local delivery of nuclear factor-κB decoy attenuates in-stent restenosis in hypercholesterolemic rabbits

ohtani, K., Egashira, K., Nakano, K., Zhao, G., Funakoshi, K., Ihara, Y., Kimura, S., Tominaga, R., Morishita, R. & Sunagawa, K., Dec 1 2006, In : Circulation. 114, 25, p. 2773-2779 7 p.

Research output: Contribution to journalArticle

Stents
Rabbits
Polymers
Chemokine CCL2
Iliac Artery
7 Citations (Scopus)

Tumor necrosis factor-α antisense transfer remarkably improves hepatic graft viability

Yoshizumi, T., Yonemitsu, Y., Ikeda, Y., Kaneda, Y., Yanaga, K., Sugimachi, K. & Sueishi, K., May 1 2006, In : Liver International. 26, 4, p. 451-456 6 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor-alpha
Transplants
Liver
Kupffer Cells
Oligodeoxyribonucleotides
2005
69 Citations (Scopus)

Angiogenesis and lymphangiogenesis and expression of lymphangiogenic factors in the atherosclerotic intima of human coronary arteries

Nakano, T., Nakashima, Y., Yonemitsu, Y., Sumiyoshi, S., Chen, Y. X., Akishima, Y., Ishii, T., Iida, M. & Sueishi, K., Jan 1 2005, In : Human Pathology. 36, 4, p. 330-340 11 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor D
Lymphangiogenesis
Vascular Endothelial Growth Factor C
Lymphatic Vessels
CD44 Antigens
24 Citations (Scopus)

Cytoplasmic expression and extracellular deposition of an antiangiogenic factor, pigment epithelium-derived factor, in human atherosclerotic plaques

Baba, H., Yonemitsu, Y., Nakano, T., Onimaru, M., Miyazaki, M., Ikeda, Y., Sumiyoshi, S., Ueda, Y., Hasegawa, M., Yoshino, I., Maehara, Y. & Sueishi, K., Sep 1 2005, In : Arteriosclerosis, thrombosis, and vascular biology. 25, 9, p. 1938-1944 7 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Coronary Vessels
Staining and Labeling
Microvessels
Atherosclerosis
7 Citations (Scopus)

Ex vivo electroporation as a potent new strategy for nonviral gene transfer into autologous vein grafts

Yamaoka, T., Yonemitsu, Y., Komori, K., Baba, H., matsumoto, T., Onohara, T. & Maehara, Y., Nov 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 289, 5 58-5

Research output: Contribution to journalArticle

Electroporation
Veins
Transplants
Genes
Adventitia
112 Citations (Scopus)

Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination

Yamamoto, K., Hirano, S., Ishiai, M., Morishima, K., Kitao, H., Namikoshi, K., Kimura, M., Matsushita, N., Arakawa, H., Buerstedde, J. M., Komatsu, K., Thompson, L. H. & Takata, M., Jan 1 2005, In : Molecular and Cellular Biology. 25, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Gene Conversion
Immunoglobulin Genes
Homologous Recombination
DNA Repair
70 Citations (Scopus)

Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas

Shikada, Y., Yonemitsu, Y., Koga, T., Onimaru, M., Nakano, T., Okano, S., Sata, S., Nakagawa, K., Yoshino, I., Maehara, Y. & Sueishi, K., Aug 15 2005, In : Cancer Research. 65, 16, p. 7241-7248 8 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor
Non-Small Cell Lung Carcinoma
Vascular Endothelial Growth Factor A
Neoplasms
Cell Line
13 Citations (Scopus)

The effects of flavoxate hydrochloride on voltage-dependent L-type Ca 2+ currents in human urinary bladder

Tomoda, T., Aishima, M., Takano, N., Nakano, T., Seki, N., Yonemitsu, Y., Sueishi, K., Naito, S., Ito, Y. & Teramoto, N., Dec 1 2005, In : British Journal of Pharmacology. 146, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Flavoxate
Urinary Bladder
Nifedipine
Muscle Cells
Muscle Relaxation
14 Citations (Scopus)

The use of transformed Escherichia coli for experimental angiogenesis induced by regulated in situ production of vascular endothelial growth factor - An alternative gene therapy

Celec, P., Gardlík, R., Pálffy, R., Hodosy, J., Stuchlík, S., Drahovská, H., Stuchlíková, M., Minárik, G., Lukács, J., Jurkovičová, I., Hulín, I., Turňa, J., Jakubovský, J., Kopáni, M., Danišovič, Ľ., Jandzík, D., Kúdela, M. & Yonemitsu, Y., Jan 7 2005, In : Medical Hypotheses. 64, 3, p. 505-511 7 p.

Research output: Contribution to journalArticle

Complementary Therapies
Genetic Therapy
Vascular Endothelial Growth Factor A
Escherichia coli
Myocardial Ischemia
45 Citations (Scopus)

Tumor necrosis factor and vascular endothelial growth factor induce endothelial integrin repertories, regulating endovascular differentiation and apoptosis in a human extravillous trophoblast cell line

Fukushima, K., Miyamoto, S., Tsukimori, K., Kobayashi, H., Seki, H., Takeda, S., Egashira, K., ohtani, K., Shibuya, M. & Nakano, H., Jul 1 2005, In : Biology of Reproduction. 73, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

Trophoblasts
Integrins
Vascular Endothelial Growth Factor A
Tumor Necrosis Factor-alpha
Apoptosis
2004
110 Citations (Scopus)

Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells

ohtani, K., Egashira, K., Ken-Ichi, H., Zhao, Q., Kitamoto, S., Ishibashi, M., Usui, M., Inoue, S., Yonemitsu, Y., Sueishi, K., Sata, M., Shibuya, M. & Sunagawa, K., Oct 19 2004, In : Circulation. 110, 16, p. 2444-2452 9 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Monocytes
Wounds and Injuries
Genes
Vascular Endothelial Growth Factor Receptor-1
149 Citations (Scopus)

Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling

Ishibashi, M., Ken-Ichi, H., Zhao, Q., Inoue, S., ohtani, K., Kitamoto, S., Tsuchihashi, M., Sugaya, T., Charo, I. F., Kura, S., Tsuzuki, T., Ishibashi, T., Takeshita, A. & Egashira, K., May 14 2004, In : Circulation research. 94, 9, p. 1203-1210 8 p.

Research output: Contribution to journalArticle

CCR2 Receptors
Monocytes
Hypertension
Inflammation
Angiotensin II
66 Citations (Scopus)

Essential role of PDGFRα-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo role of PDGFRα during angiogenesis

Tsutsumi, N., Yonemitsu, Y., Shikada, Y., Onimaru, M., Tanii, M., Okano, S., Kaneko, K., Hasegawa, M., Hashizume, M., Maehara, Y. & Sueishi, K., May 14 2004, In : Circulation Research. 94, 9, p. 1186-1194 9 p.

Research output: Contribution to journalArticle

70-kDa Ribosomal Protein S6 Kinases
Platelet-Derived Growth Factor Receptors
Sirolimus
Neoplasms
Vascular Endothelial Growth Factor A
8 Citations (Scopus)

Growth pattern correlates with the distribution of basement membrane and prognosis in lung adenocarcinoma

Matsuo, Y., Hashimoto, S., Koga, T., Yonemitsu, Y., Yoshino, I., Sugimachi, K., Honda, H., Masuda, K. & Sueishi, K., Jan 1 2004, In : Pathology Research and Practice. 200, 7-8, p. 517-529 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-2
Matrix Metalloproteinases
Basement Membrane
Antigens
Growth
201 Citations (Scopus)

Hypertensive Myocardial Fibrosis and Diastolic Dysfunction: Another Model of Inflammation?

Kuwahara, F., Kai, H., Tokuda, K., Takeya, M., Takeshita, A., Egashira, K. & Imaizumi, T., Apr 1 2004, In : Hypertension. 43, 4, p. 739-745 7 p.

Research output: Contribution to journalArticle

Muscle Cells
Fibrosis
Macrophages
Inflammation
Chemotactic Factors
49 Citations (Scopus)

SOC1 inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein

Kamio, M., Yoshida, T., Ogata, H., Douchi, T., Nagata, Y., Inoue, M., Hasegawa, M., Yonemitsu, Y. & Yoshimura, A., Apr 15 2004, In : Oncogene. 23, 17, p. 3107-3115 9 p.

Research output: Contribution to journalArticle

Papillomaviridae
Proteolysis
Cytokines
Interferons
Retinoblastoma Protein
60 Citations (Scopus)

The relative contributions of each subset of ocular infiltrated cells in experimental choroidal neovascularisation

Tsutsumi-Miyahara, C., Sonoda, K., Egashira, K., Ishibashi, M., Qiao, H., Oshima, T., Murata, T., Miyazaki, M., Charo, I. F., Hamano, S. & Ishibashi, T., Sep 1 2004, In : British Journal of Ophthalmology. 88, 9, p. 1217-1222 6 p.

Research output: Contribution to journalArticle

Choroidal Neovascularization
Light Coagulation
Neutrophils
Macrophages
Natural Killer Cells
66 Citations (Scopus)

The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization

Miyoshi, K., Wakioka, T., Nishinakamura, H., Kamio, M., Yang, L., Inoue, M., Hasegawa, M., Yonemitsu, Y., Komiya, S. & Yoshimura, A., Jul 22 2004, In : Oncogene. 23, 33, p. 5567-5576 10 p.

Research output: Contribution to journalArticle

Cell Movement
Actins
Neoplasm Metastasis
Stress Fibers
Extracellular Signal-Regulated MAP Kinases
9 Citations (Scopus)

Vascular endothelial growth factor - Basic science and its clinical implications

Celec, P. & Yonemitsu, Y., Oct 1 2004, In : Pathophysiology. 11, 2, p. 69-75 7 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Physiological Phenomena
Coronary Artery Disease
Therapeutics
Research
2003
51 Citations (Scopus)

Downregulation of vascular angiotensin II type 1 receptor by thyroid hormone

Fukuyama, K., Ichiki, T., Takeda, K., Tokunou, T., Iino, N., Masuda, S., Ishibashi, M., Egashira, K., Shimokawa, H., Hirano, K., Kanaide, H. & Takeshita, A., Mar 1 2003, In : Hypertension. 41, 3 I, p. 598-603 6 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Thyroid Hormones
Angiotensin II
Blood Vessels
Down-Regulation
81 Citations (Scopus)

Gene therapy expressing amino-terminal truncated monocyte chemoattractant protein-1 prevents renal ischemia-reperfusion injury

Furuichi, K., Wada, T., Iwata, Y., Kitagawa, K., Kobayashi, K. I., Hashimoto, H., Ishiwata, Y., Tomosugi, N., Mukaida, N., Matsushima, K., Egashira, K. & Yokoyama, H., Apr 1 2003, In : Journal of the American Society of Nephrology. 14, 4, p. 1066-1071 6 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Reperfusion Injury
Genetic Therapy
Kidney
Reperfusion
21 Citations (Scopus)

Intramuscular gene transfer of FGF-2 attenuates endothelial dysfunction and inhibits intimal hyperplasia of vein grafts in poor-runoff limbs of rabbit

Shoji, T., Yonemitsu, Y., Komori, K., Tanii, M., Itoh, H., Sata, S., Shimokawa, H., Hasegawa, M., Sueishi, K. & Maehara, Y., Jul 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 285, 1 54-1

Research output: Contribution to journalArticle

Tunica Intima
Fibroblast Growth Factor 2
Sendai virus
Hyperplasia
Veins
33 Citations (Scopus)

In vivo delivery of glial cell-derived neurotrophic factor across the blood-brain barrier by gene transfer into brain capillary endothelial cells

Jiang, C., Koyabu, N., Yonemitsu, Y., Shimazoe, T., Watanabe, S., Naito, M., Tsuruo, T., Ohtani, H. & Sawada, Y., Aug 10 2003, In : Human Gene Therapy. 14, 12, p. 1181-1191 11 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Blood-Brain Barrier
Neuroglia
Endothelial Cells
Brain
137 Citations (Scopus)

Molecular mechanisms mediating inflammation in vascular disease: Special reference to monocyte chemoattractant protein-1

Egashira, K., Mar 1 2003, In : Hypertension. 41, 3 II, p. 834-841 8 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Vascular Diseases
Inflammation
Monocytes
Blood Vessels
19 Citations (Scopus)

Preservation of endothelial function by the HMG-CoA reductase inhibitor fluvastatin through its lipid-lowering independent antioxidant properties in atherosclerotic rabbits

Mitani, H., Egashira, K., Ohashi, N., Yoshikawa, M., Niwa, S., Nonomura, K., Nakashima, A. & Kimura, M., Jun 12 2003, In : Pharmacology. 68, 3, p. 121-130 10 p.

Research output: Contribution to journalArticle

fluvastatin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Antioxidants
Cholesterol
Rabbits
20 Citations (Scopus)

Recombinant Sendai virus vectors for activated T lymphocytes

Okano, S., Yonemitsu, Y., Nagata, S., Sata, S., Onimaru, M., Nakagawa, K., Tomita, Y., Kishihara, K., Hashimoto, S., Nakashima, Y., Sugimachi, K., Hasegawa, M. & Sueishi, K., Aug 1 2003, In : Gene Therapy. 10, 16, p. 1381-1391 11 p.

Research output: Contribution to journalArticle

Sendai virus
T-Lymphocytes
Antigens
Genetic Therapy
Genes
28 Citations (Scopus)

Simian immunodeficiency virus-based lentivirus vector for retinal gene transfer: A preclinical safety study in adult rats

Ikeda, Y., Goto, Y., Yonemitsu, Y., Miyazaki, M., Sakamoto, T., Ishibashi, T., Tabata, T., Ueda, Y., Hasegawa, M., Tobimatsu, S. & Sueishi, K., Jul 1 2003, In : Gene Therapy. 10, 14, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Lentivirus
Retina
Transgenes
Safety
198 Citations (Scopus)

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization

Tsutsumi, C., Sonoda, K., Egashira, K., Qiao, H., Hisatomi, T., nakao, S., Ishibashi, M., Charo, I. F., Sakamoto, T., Murata, T. & Ishibashi, T., Jul 1 2003, In : Journal of Leukocyte Biology. 74, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Choroidal Neovascularization
Macrophages
Knockout Mice
CCR2 Receptors
B7 Antigens
2002
42 Citations (Scopus)

Administration of a decoy against the activator protein-1 binding site suppresses neointimal thickening in rabbit balloon-injured arteries

Kume, M., Komori, K., matsumoto, T., Onohara, T., Takeuchi, K., Yonemitsu, Y. & Sugimachi, K., Mar 12 2002, In : Circulation. 105, 10, p. 1226-1232 7 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Protein Binding
Arteries
Binding Sites
Rabbits
347 Citations (Scopus)

Adverse outcomes of interrupted precordial compression during automated defibrillation

Nakamura, R., Egashira, K., Machida, Y., Hayashidani, S., Takeya, M., Utsumi, H., Tsutsui, H. & Takeshita, A., Jul 16 2002, In : Circulation. 106, 3, p. 368-372 5 p.

Research output: Contribution to journalArticle

Shock
Defibrillators
Cardiopulmonary Resuscitation
Thorax
Ventricular Fibrillation
194 Citations (Scopus)

Angiogenic gene therapy for experimental critical limb ischemia: Acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2

Masaki, I., Yonemitsu, Y., Yamashita, A., Sata, S., Tanii, M., Komori, K., Nakagawa, K., Hou, X., Nagai, Y., Hasegawa, M., Sugimachi, K. & Sueishi, K., May 17 2002, In : Circulation research. 90, 9, p. 966-973 8 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Genetic Therapy
Vascular Endothelial Growth Factor A
Ischemia
Extremities
79 Citations (Scopus)

Angiotensin-converting enzyme activity is involved in the mechanism of increased endogenous nitric oxide synthase inhibitor in patients with type 2 diabetes mellitus

Akira, I., Egashira, K., Takahiro, N., Kouhei, M. & Akira, T., Sep 1 2002, In : Circulation Journal. 66, 9, p. 811-815 5 p.

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Nitric Oxide Synthase
Type 2 Diabetes Mellitus
von Willebrand Factor
Perindopril
87 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats

Ikeda, Y., Yonemitsu, Y., Kataoka, C., Kitamoto, S., Yamaoka, T., Nishida, K. I., Takeshita, A., Egashira, K. & Sueishi, K., Nov 1 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 283, 5 52-5

Research output: Contribution to journalArticle

Chemokine CCL2
Chemotactic Factors
Pulmonary Hypertension
Genetic Therapy
Macrophages
80 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys.

Usui, M., Egashira, K., ohtani, K., Kataoka, C., Ishibashi, M., Ken-Ichi, H., Katoh, M., Zhao, Q., Kitamoto, S. & Takeshita, A., Jan 1 2002, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16, 13, p. 1838-1840 3 p.

Research output: Contribution to journalArticle

Gene therapy
Chemokine CCL2
Balloons
Genetic Therapy
Hyperplasia
210 Citations (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice

Inoue, S., Egashira, K., Ni, W., Kitamoto, S., Usui, M., Otani, K., Ishibashi, M., Ken-Ichi, H., Nishida, K. I. & Takeshita, A., Nov 19 2002, In : Circulation. 106, 21, p. 2700-2706 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Apolipoproteins E
Knockout Mice
Genetic Therapy
Atherosclerosis