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2018

Changes in HER2 expression and amplification status following preoperative chemotherapy for gastric cancer

Shu, S., Iimori, M., Nakanishi, R., Jogo, T., Saeki, H., Oki, E. & Maehara, Y., Nov 1 2018, In : In Vivo. 32, 6, p. 1491-1498 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Characterization of changes in HbA1c in patients with and without secondary failure after metformin treatments by a population pharmacodynamic analysis using mixture models

Tamaki, Y., Maema, K., Kakara, M., Fukae, M., Kinoshita, R., Kashihara, Y., Muraki, S., Hirota, T. & Ieiri, I., Dec 1 2018, In : Drug metabolism and pharmacokinetics. 33, 6, p. 264-269 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Chemoselective Catalytic Dehydrogenative Cross-Coupling of 2-Acylimidazoles: Mechanistic Investigations and Synthetic Scope

Tanaka, T., Hashiguchi, K., Tanaka, T., Yazaki, R. & Ohshima, T., Sep 7 2018, In : ACS Catalysis. 8, 9, p. 8430-8440 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Chronopharmacology based on molecular clock

Ohdo, S., Jan 1 2018, In : Oral Therapeutics and Pharmacology. 37, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function /631/80/105 /631/208/199 /38 /38/35 /38/109 /38/77 /13/51 /13/109 article

Tsurudome, Y., Koyanagi, S., Kanemitsu, T., Katamune, C., Oda, M., Kanado, Y., Kato, M., Morita, A., Tahara, Y., Matsunaga, N., Shibata, S. & Ohdo, S., Dec 1 2018, In : Scientific reports. 8, 1, 9072.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Clinical significance of programmed cell death-ligand 1 expression and the immune microenvironment at the invasive front of colorectal cancers with high microsatellite instability

Korehisa, S., Oki, E., Iimori, M., Nakaji, Y., Shimokawa, M., Saeki, H., Okano, S., Oda, Y. & Maehara, Y., Feb 15 2018, In : International Journal of Cancer. 142, 4, p. 822-832 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer

Inoue, Y., Yamashita, N., Kitao, H., Tanaka, K., Saeki, H., Oki, E., Oda, Y., Tokunaga, E. & Maehara, Y., Aug 2018, In : Clinical Breast Cancer. 18, 4, p. e643-e650

Research output: Contribution to journalArticle

2 Citations (Scopus)

Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance

Koshimizu, T. A., Honda, K., Nagaoka-Uozumi, S., Ichimura, A., Kimura, I., Nakaya, M., Sakai, N., Shibata, K., Ushijima, K., Fujimura, A., Hirasawa, A., Kurose, H., Tsujimoto, G., Tanoue, A. & Takano, Y., Jun 1 2018, In : Nature Neuroscience. 21, 6, p. 820-833 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
10 Citations (Scopus)

Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1α protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Müller) cells

Kusunose, N., Akamine, T., Kobayashi, Y., Yoshida, S., Kimoto, K., Yasukochi, S., Matsunaga, N., Koyanagi, S., Ohdo, S. & Kubota, T., 2018, (Accepted/In press) In : Japanese Journal of Ophthalmology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., Oct 15 2018, In : Analytical Biochemistry. 559, p. 91-93 3 p.

Research output: Contribution to journalArticle

Detection and inhibition of redox reaction and lipid derived radicals

Yamada, K-I., Jan 1 2018, In : Drug Delivery System. 33, 3, p. 197-203 7 p.

Research output: Contribution to journalArticle

Development of a colloidal gold nanoparticle-based immunochromatographic strip for the one-step detection of miroestrol and puerarin

Krittanai, S., Kitisripanya, T., Udomsin, O., Tanaka, H., Sakamoto, S., Juengwatanatrakul, T. & Putalun, W., Nov 2018, In : Biomedical Chromatography. 32, 11, e4330.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel

Cui, Q., Tanaka, H., Shoyama, Y., Ye, H. T., Li, F., Tian, E. W., Wu, Y. S. & Chao, Z., May 1 2018, In : Phytochemical Analysis. 29, 3, p. 284-289 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development of an immunochromatographic strip incorporating anti-mitragynine monoclonal antibody conjugated to colloidal gold for kratom alkaloids detection

Limsuwanchote, S., Putalun, W., Tanaka, H., Morimoto, S., Keawpradub, N. & Wungsintaweekul, J., Jul 2018, In : Drug Testing and Analysis. 10, 7, p. 1168-1175 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
17 Citations (Scopus)
1 Citation (Scopus)

Diacylglycerol kinase β induces filopodium formation via its C1, catalytic and carboxy-terminal domains and interacts with the Rac1-GTPase-activating protein, β2-chimaerin

Maeda, Y., Shibata, K., Akiyama, R., Murakami, Y., Takao, S., Murakami, C., Takahashi, D., Sakai, H. & Sakane, F., Sep 26 2018, In : Biochemical and Biophysical Research Communications. 504, 1, p. 54-60 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Different expression systems resulted in varied binding properties of anti-paclitaxel single-chain variable fragment antibody clone 1C2

Yusakul, G., Sakamoto, S., Nuntawong, P., Tanaka, H. & Morimoto, S., Jan 1 2018, In : Journal of Natural Medicines. 72, 1, p. 310-316 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro

Kawashiri, T., Miyagi, A., Shimizu, S., Shigematsu, N., Kobayashi, D. & Shimazoe, T., Jun 2018, In : Journal of Pharmacological Sciences. 137, 2, p. 202-211 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1

Tashiro, S., Caaveiro, J. M. M., Nakakido, M., Tanabe, A., Nagatoishi, S., Tamura, Y., Matsuda, N., Liu, D., Hoang, Q. Q. & Tsumoto, K., Sep 21 2018, In : ACS Chemical Biology. 13, 9, p. 2783-2793 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Discovery of 2-[(E)-2-(7-fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin- 1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine hydrochloride as a highly selective PDE10A inhibitor

Kadoh, Y., Miyoshi, H., Matsumura, T., Tanaka, Y., Hongu, M., Kimura, M., Takedomi, K., Omori, K., Kotera, J., Sasaki, T., Kobayashi, T., Taniguchi, H., Watanabe, Y., Kojima, K., Sakamoto, T., Himiyama, T. & Kawanishi, E., 2018, In : Chemical and Pharmaceutical Bulletin. 66, 3, p. 243-250 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effects of Derinat on ischemia-reperfusion-induced pressure ulcer mouse model

Liu, J., Rybakina, E. G., Korneva, E. A. & Noda, M., Oct 2018, In : Journal of Pharmacological Sciences. 138, 2, p. 123-130 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of using the adherence score sheet according to application timing in improving medication adherence in SETSUYAKU-BAG campaign

Kobayashi, D., Koyanagi, K., Kubota, T., Maruyama, M., Miisho, T., Kaneko, E., Kawanami, M., Kihara, T., Takaki, J., Nakashiba, T., Nagatomi, S., Seo, T., Tanaka, T. & Shimazoe, T., 2018, In : Yakugaku Zasshi. 138, 12, p. 1549-1559 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Efficient Mass Spectral Analysis of Active Transporters Overexpressed in Escherichia coli

Kawakami, M., Juge, N., Kato, Y., Omote, H., Moriyama, Y. & Miyaji, T., Mar 2 2018, In : Journal of Proteome Research. 17, 3, p. 1108-1119 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
4 Citations (Scopus)

Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells

Takaoka, Y., Uchinomiya, S., Kobayashi, D., Endo, M., Hayashi, T., Fukuyama, Y., Hayasaka, H., Miyasaka, M., Ueda, T., Shimada, I. & Hamachi, I., Jun 14 2018, In : Chem. 4, 6, p. 1451-1464 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Enhancement effect on the chemiluminescence of acridinium esters under neutral conditions

Nakazono, M. & Nanbu, S., Mar 2018, In : Luminescence. 33, 2, p. 345-348 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Enzyme linked immunosorbent assay for total potent estrogenic miroestrol and deoxymiroestrol of Pueraria candollei, a Thai herb for menopause remedy

Yusakul, G., Kitisripanya, T., Juengwatanatrakul, T., Sakamoto, S., Tanaka, H. & Putalun, W., Jun 1 2018, In : Journal of Natural Medicines. 72, 3, p. 641-650 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system

Kimura, H., Matsunaga, N., Kakimoto, K., Watanabe, M., Tsuruta, A., Kusunose, N., Shiromizu, S., Koyanagi, S. & Ohdo, S., Sep 5 2018, In : Biochemical and Biophysical Research Communications. 503, 2, p. 1063-1069 7 p.

Research output: Contribution to journalArticle

Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer

Yamashita, N., Tokunaga, E., Iimori, M., Inoue, Y., Tanaka, K., Kitao, H., Saeki, H., Oki, E. & Maehara, Y., Oct 2018, In : Clinical Breast Cancer. 18, 5, p. e1003-e1009

Research output: Contribution to journalArticle

17 Citations (Scopus)

Evaluation of simultaneous binding of Chromomycin A3 to the multiple sites of DNA by the new restriction enzyme assay

Murase, H., Noguchi, T. & Sasaki, S., Jun 1 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 10, p. 1832-1835 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)

Fluorescence tumor-imaging using a thermo-responsive molecule with an emissive aminoquinoline derivative

Araki, T., Fuchi, Y., Murayama, S., Shiraishi, R., Oyama, T., Aso, M., Aoki, I., Kobayashi, S., Yamada, K. I. & Karasawa, S., Oct 2 2018, In : Nanomaterials. 8, 10, 782.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jul 27 2018, In : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journalArticle

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jan 1 2018, In : Nucleic acids research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Genotoxic Responses of Mitochondrial Oxygen Consumption Rate and Mitochondrial Semiquinone Radicals in Tumor Cells

Yamamoto, K., Yasui, H., Bo, T., Yamamori, T., Hiraoka, W., Yamasaki, T., Yamada, K. I. & Inanami, O., Aug 1 2018, In : Applied Magnetic Resonance. 49, 8, p. 837-851 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Gliotransmitters and cytokines in the control of blood-brain barrier permeability

Osipova, E. D., Semyachkina-Glushkovskaya, O. V., Morgun, A. V., Pisareva, N. V., Malinovskaya, N. A., Boitsova, E. B., Pozhilenkova, E. A., Belova, O. A., Salmin, V. V., Taranushenko, T. E., Noda, M. & Salmina, A. B., Jul 26 2018, In : Reviews in the Neurosciences. 29, 5, p. 567-591 25 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Growth suppression of human colorectal cancer cells with mutated KRAS by 3-deaza-cytarabine in 3d floating culture

Luo, H., Nishi, K., Ishikura, S., Swain, A., Morishige, N., Yazaki, R., Ohshima, T., Shirasawa, S. & Tsunoda, T., Jul 2018, In : Anticancer research. 38, 7, p. 4247-4256 10 p.

Research output: Contribution to journalArticle

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., Aug 1 2018, In : Journal of cell science. 131, 15

Research output: Contribution to journalArticle

5 Citations (Scopus)

Gut microbiota-derived D-serine protects against acute kidney injury

Nakade, Y., Iwata, Y., Furuichi, K., Mita, M., Hamase, K., Konno, R., Miyake, T., Sakai, N., Kitajima, S., Toyama, T., Shinozaki, Y., Sagara, A., Miyagawa, T., Hara, A., Shimizu, M., Kamikawa, Y., Sato, K., Oshima, M., Yoneda-Nakagawa, S., Yamamura, Y. & 8 others, Kaneko, S., Miyamoto, T., Katane, M., Homma, H., Morita, H., Suda, W., Hattori, M. & Wada, T., Oct 18 2018, In : JCI Insight. 3, 20

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration

Kim, T. H., Yang, Y. M., Han, C. Y., Koo, J. H., Oh, H., Kim, S. S., You, B. H., Choi, Y. H., Park, T. S., Lee, C. H., Kurose, H., Noureddin, M., Seki, E., Wan, Y. J. Y., Choi, C. S. & Kim, S. G., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5587-5602 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence

Nishimura, A., Shimauchi, T., Tanaka, T., Shimoda, K., Toyama, T., Kitajima, N., Ishikawa, T., Shindo, N., Numaga-Tomita, T., Yasuda, S., Sato, Y., Kuwahara, K., Kumagai, Y., Akaike, T., Ide, T., Ojida, A., Mori, Y. & Nishida, M., Nov 13 2018, In : Science Signaling. 11, 556, eaat5185.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Imaging Doxorubicin Free Radical in Mice with Overhauser Enhanced MRI and its Tumor Suppression Effect in Mice

Kato, N., Sato, S., Yamada, K. I. & Ichikawa, K., Aug 1 2018, In : Applied Magnetic Resonance. 49, 8, p. 869-879 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
7 Citations (Scopus)

Interleukin-27 controls basal pain threshold in physiological and pathological conditions

Sasaguri, T., Taguchi, T., Murata, Y., Kobayashi, K., Iizasa, S., Iizasa, E., Tsuda, M., Hirakawa, N., Hara, H., Yoshida, H. & Yasaka, T., Dec 1 2018, In : Scientific reports. 8, 1, 11022.

Research output: Contribution to journalArticle

3 Citations (Scopus)