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2018

Internal-Edge-Substituted Coumarin-Fused [6]Helicenes: Asymmetric Synthesis, Structural Features, and Control of Self-Assembly

Usui, K., Yamamoto, K., Ueno, Y., Igawa, K., Hagihara, R., Masuda, T., Ojida, A., Karasawa, S., Tomooka, K., Hirai, G. & Suemune, H., Oct 1 2018, In : Chemistry - A European Journal. 24, 55, p. 14617-14621 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody

Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J. M. M. & Tsumoto, K., Jul 1 2018, In : Journal of biochemistry. 164, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Introduction of a glycosylation site in the constant region decreases the aggregation of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., Sep 5 2018, In : Biochemical and Biophysical Research Communications. 503, 2, p. 752-756 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Imai, T., Matsumura, T., Mayer-Lambertz, S., Wells, C. A., Ishikawa, E., Butcher, S. K., Barnett, T. C., Walker, M. J., Imamura, A., Ishida, H., Ikebe, T., Miyamoto, T., Ato, M., Ohga, S., Lepenies, B., Van Sorge, N. M. & Yamasaki, S., Nov 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10662-E10671

Research output: Contribution to journalArticle

11 Citations (Scopus)

Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescence

Fuchi, Y., Fukuda, T. & Sasaki, S., Jul 23 2018, In : Bioorganic and Medicinal Chemistry. 26, 12, p. 3254-3260 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Lycodine-type alkaloids and their glycosides from Lycopodiastrum casuarinoides

Wang, L. L., Hao, L. J., Zhou, Z. B., Zhu, X. L., Shi, Z. H., Miyamoto, T. & Pan, K., Oct 2018, In : Phytochemistry. 154, p. 63-72 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites

Watanabe, S., Iimori, M., Chan, D. V., Hara, E., Kitao, H. & Maehara, Y., Dec 1 2018, In : Scientific reports. 8, 1, 10888.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury

Homma, T., Shirato, T., Akihara, R., Kobayashi, S., Lee, J., Yamada, K. I., Miyata, S., Takahashi, M. & Fujii, J., Sep 15 2018, In : Toxicology Letters. 294, p. 37-43 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

miR-3148 is a novel onco-microRNA that potentiates tumor growth in vivo

Akamine, T., Morodomi, Y., Harada, Y., Teraishi, K., Tagawa, T., Okamoto, T., Maehara, Y. & Yonemitsu, Y., Oct 2018, In : Anticancer research. 38, 10, p. 5693-5701 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Modification of the aminopyridine unit of 2-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences

Wang, L., Taniguchi, Y., Okamura, H. & Sasaki, S., Jan 1 2018, In : Nucleic acids research. 46, 17, p. 8679-8688 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

Tashima, T., Nagatoishi, S., Caaveiro, J. M. M., Nakakido, M., Sagara, H., Kusano-Arai, O., Iwanari, H., Mimuro, H., Hamakubo, T., Ohnuma, S. I. & Tsumoto, K., Dec 1 2018, In : Communications Biology. 1, 1, 33.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Natural antibody against neuroblastoma of TH-MYCN transgenic mice does not correlate with spontaneous regression

Kawakubo, N., Harada, Y., Ishii, M., Souzaki, R., Kinoshita, Y., Tajiri, T., Taguchi, T. & Yonemitsu, Y., Sep 10 2018, In : Biochemical and Biophysical Research Communications. 503, 3, p. 1666-1673 8 p.

Research output: Contribution to journalArticle

Neuropathic pain inhibitor, RAP-103, is a potent inhibitor of microglial CCL1/CCR8

Noda, M., Tomonaga, D., Kitazono, K., Yoshioka, Y., Liu, J., Rousseau, J. P., Kinkead, R., Ruff, M. R. & Pert, C. B., Oct 2018, In : Neurochemistry International. 119, p. 184-189 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

New strategies for exercise-mimetic medication

Oda, S., Numaga-Tomita, T. & Nishida, M., Jan 1 2018, In : Yakugaku Zasshi. 138, 10, p. 1257-1262 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nucleosome positioning and gene regulation of the SGLT2 gene in the renal proximal tubular epithelial cells

Takesue, H., Hirota, T., Tachimura, M., Tokashiki, A. & Ieiri, I., Sep 1 2018, In : Molecular Pharmacology. 94, 3, p. 953-962 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Oleanane-type glycosides from the roots of Weigela florida “rumba” and evaluation of their antibody recognition

Champy-Tixier, A. S., Mitaine-Offer, A. C., Real Fernández, F., Miyamoto, T., Tanaka, C., Papini, A. M. & Lacaille-Dubois, M. A., Jul 2018, In : Fitoterapia. 128, p. 198-203 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the antitumor effects of aldehyde dehydrogenase inhibitor

Naoya, M., Ogino, T., Hara, Y., Tanaka, T., Satoru, K. & Ohdo, S., Jul 1 2018, In : Cancer Research. 78, 13, p. 3698-3708 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Optimizing the dosing schedule of L-asparaginase improves its anti-tumor activity in breast tumor-bearing mice

Shiromizu, S., Kusunose, N., Matsunaga, N., Koyanagi, S. & Ohdo, S., Apr 2018, In : Journal of Pharmacological Sciences. 136, 4, p. 228-233 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Optogenetic activation of non-nociceptive aβ fibers induces neuropathic pain-like sensory and emotional behaviors after nerve injury in rats

Tashima, R., Koga, K., Sekine, M., Kanehisa, K., Kohro, Y., Tominaga, K., Matsushita, K., Tozaki-Saitoh, H., Fukazawa, Y., Inoue, K., Yawo, H., Furue, H. & Tsuda, M., Jan 1 2018, In : eNeuro. 5, 1, e0450-17.2018.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Andriamisaina, N., Mitaine-Offer, A. C., Pruvot, B., Chluba, J., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 2018, In : Natural product communications. 13, 4, p. 403-406 4 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Population Pharmacodynamic Analysis of Uric Acid–Lowering Effects of Febuxostat Based on Electronic Medical Records in Two Hospitals

Muraki, S., Moriki, K., Shigematsu, S., Fukae, M., Kakara, M., Yamashita, D., Hirota, T., Takane, H., Shimada, M., Hirakawa, M. & Ieiri, I., Mar 2018, In : Journal of Clinical Pharmacology. 58, 3, p. 304-313 10 p.

Research output: Contribution to journalArticle

Population Pharmacokinetics and Pharmacodynamics of Oral Propranolol in Pediatric Patients With Infantile Hemangioma

Takechi, T., Kumokawa, T., Kato, R., Higuchi, T., Kaneko, T. & Ieiri, I., Oct 2018, In : Journal of Clinical Pharmacology. 58, 10, p. 1361-1370 10 p.

Research output: Contribution to journalArticle

Prolonged stimulation of β2-adrenergic receptor with β2-agonists impairs insulin actions in H9c2 cells

Parichatikanond, W., Nishimura, A., Nishida, M. & Mangmool, S., Nov 2018, In : Journal of Pharmacological Sciences. 138, 3, p. 184-191 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Psychological assessment of acute schizophrenia patients who experienced seclusion either alone or in combination with restraint

Eguchi, R., Onozuka, D., Ikeda, K., Kuroda, K., Ieiri, I. & Hagihara, A., May 1 2018, In : International Journal of Psychiatry in Medicine. 53, 3, p. 171-188 18 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)
3 Citations (Scopus)

Self-Assembled Biradical Ureabenzene Nanoparticles for Magnetic Resonance Imaging

Morishita, K., Ueki, S., Fuchi, Y., Murayama, S., Kaneko, T., Narita, N., Kobayashi, S., Hirai, G., Aoki, I. & Karasawa, S., Dec 28 2018, In : ACS Applied Nano Materials. 1, 12, p. 6967-6975 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., Jan 2018, In : PloS one. 13, 1, e0191532.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2 Citations (Scopus)

Sequential actions of immune effector cells induced by viral activation of dendritic cells to eliminate murine neuroblastoma

Kawakubo, N., Tanaka, S., Kinoshita, Y., Tajiri, T., Yonemitsu, Y. & Taguchi, T., Aug 2018, In : Journal of Pediatric Surgery. 53, 8, p. 1615-1620 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
4 Citations (Scopus)

Stable and selective antiparallel type triplex DNA formation by targeting a GC base pair with the TFO containing one N2-phenyl-2-deoxyguanosine

Taniguchi, Y., Miyazaki, M., Matsueda, N., Wang, L., Okamura, H. & Sasaki, S., Jan 1 2018, In : Chemical and Pharmaceutical Bulletin. 66, 6, p. 624-631 8 p.

Research output: Contribution to journalArticle

Strategy for Catalytic Chemoselective Cross-Enolate Coupling Reaction via a Transient Homocoupling Dimer

Tanaka, T., Tanaka, T., Tsuji, T., Yazaki, R. & Ohshima, T., Jun 15 2018, In : Organic letters. 20, 12, p. 3541-3544 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Structural and enzymatic properties of mammalian D-glutamate cyclase

Katane, M., Ariyoshi, M., Tateishi, S., Koiwai, S., Takaku, K., Nagai, K., Nakayama, K., Saitoh, Y., Miyamoto, T., Sekine, M., Mita, M., Hamase, K., Matoba, S. & Homma, H., Sep 15 2018, In : Archives of Biochemistry and Biophysics. 654, p. 10-18 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Structure–function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity

Shiroishi, M., Ito, Y., Shimokawa, K., Lee, J. M., Kusakabe, T. & Ueda, T., May 4 2018, In : Journal of Biological Chemistry. 293, 18, p. 7008-7016 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synthesis of azaheterocycles and related molecules by Tf2NH-catalyzed cycloadditions

Shindo, N. & Takasu, K., Jan 1 2018, In : Heterocycles. 96, 2, p. 195-212 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Synthesis of dendritic bisphosphonates as bone targeting ligands

Shimoda, K., Mitsuoka, T., Ueda, K., Suemune, H., Hirai, G. & Aso, M., Dec 19 2018, In : Tetrahedron Letters. 59, 51, p. 4528-4531 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Temporal kinetics of microgliosis in the spinal dorsal horn after peripheral nerve injury in rodents

Kohno, K., Kitano, J., Kohro, Y., Tozaki-Saitoh, H., Inoue, K. & Tsuda, M., Jan 1 2018, In : Biological and Pharmaceutical Bulletin. 41, 7, p. 1096-1102 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Terpenoid glycosides from the root's barks of Eriocoelum microspermum Radlk. ex Engl.

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delaude, C. & Lacaille-Dubois, M. A., Aug 1 2018, In : Phytochemistry. 152, p. 182-190 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The aryl hydrocarbon receptor is indispensable for dioxin-induced defects in sexually-dimorphic behaviors due to the reduction in fetal steroidogenesis of the pituitary-gonadal axis in rats

Hattori, Y., Takeda, T., Nakamura, A., Nishida, K., Shioji, Y., Fukumitsu, H., Yamada, H. & Ishii, Y., Aug 2018, In : Biochemical Pharmacology. 154, p. 213-221 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The DnaA AAA+ Domain His136 residue directs DnaB replicative helicase to the unwound region of the replication origin, oriC

Sakiyama, Y., Nishimura, M., Hayashi, C., Akama, Y., Ozaki, S. & Katayama, T., Aug 31 2018, In : Frontiers in Microbiology. 9, AUG, 2017.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The first multicenter, randomized, controlled trial of home telemonitoring for Japanese patients with heart failure: home telemonitoring study for patients with heart failure (HOMES-HF)

On Behalf Of The Homes-Hf Study Investigators, Aug 1 2018, In : Heart and Vessels. 33, 8, p. 866-876 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The MAPK Erk5 is necessary for proper skeletogenesis involving a smurf-smad-Sox9 molecular axis

Iezaki, T., Fukasawa, K., Horie, T., Park, G., Robinson, S., Nakaya, M., Fujita, H., Onishi, Y., Ozaki, K., Kanayama, T., Hiraiwa, M., Kitaguchi, Y., Kaneda, K., Yoneda, Y., Takarada, T., Guo, X. E., Kurose, H. & Hinoi, E., Jul 15 2018, In : Development (Cambridge). 145, 14, dev164004.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The relationship between fine particulate matter (PM) and schizophrenia severity

Eguchi, R., Onozuka, D., Ikeda, K., Kuroda, K., Ieiri, I. & Hagihara, A., Apr 23 2018, In : International Archives of Occupational and Environmental Health.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Thienyl-Substituted α-Ketoamide: A Less Hydrophobic Reactive Group for Photo-Affinity Labeling

Ota, E., Usui, K., Oonuma, K., Koshino, H., Nishiyama, S., Hirai, G. & Sodeoka, M., Apr 20 2018, In : ACS Chemical Biology. 13, 4, p. 876-880 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Thymidine kinase 1 loss confers trifluridine resistance without affecting 5-fluorouracil metabolism and cytotoxicity

Edahiro, K., Iimori, M., Kobunai, T., Morikawa-Ichinose, T., Miura, D., Kataoka, Y., Niimi, S., Wakasa, T., Saeki, H., Oki, E., Kitao, H. & Maehara, Y., Oct 2018, In : Molecular Cancer Research. 16, 10, p. 1483-1490 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex

Chen, T., Taniguchi, W., Chen, Q. Y., Tozaki-Saitoh, H., Song, Q., Liu, R. H., Koga, K., Matsuda, T., Kaito-Sugimura, Y., Wang, J., Li, Z. H., Lu, Y. C., Inoue, K., Tsuda, M., Li, Y. Q., Nakatsuka, T. & Zhuo, M., Dec 1 2018, In : Nature communications. 9, 1, 1886.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Triterpene saponins of the root bark of Olax obtusifolia De Wild

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delaude, C. & Lacaille-Dubois, M. A., Dec 1 2018, In : Phytochemistry Letters. 28, p. 174-178 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)