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2016

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

Toyonaga, K., Torigoe, S., Motomura, Y., Kamichi, T., Hayashi, J. M., Morita, Y. S., Noguchi, N., Chuma, Y., Kiyohara, H., Matsuo, K., Tanaka, H., Nakagawa, Y., Sakuma, T., Ohmuraya, M., Yamamoto, T., Umemura, M., Matsuzaki, G., Yoshikai, Y., Yano, I., Miyamoto, T. & 1 others, Yamasaki, S., Dec 20 2016, In : Immunity. 45, 6, p. 1245-1257 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

Dubey, B. N., Lori, C., Ozaki, S., Fucile, G., Plaza-Menacho, I., Jenal, U. & Schirmer, T., Sep 2016, In : Science Advances. 2, 9, e1600823.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Cycloart-24-ene-26-ol-3-one, a new cycloartane isolated from leaves of Aglaia exima triggers tumour necrosis factor-receptor 1-mediated caspase-dependent apoptosis in colon cancer cell line

Leong, K. H., Looi, C. Y., Loong, X. M., Cheah, F. K., Supratman, U., Litaudon, M., Mustafa, M. R. & Awang, K., Apr 2016, In : PloS one. 11, 4, e0152652.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Cycloartane-type saponins from astragalus tmoleus var. tmoleus

Avunduk, S., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., Jan 23 2016, In : Natural product communications. 11, 1, p. 37-38 2 p.

Research output: Contribution to journalArticle

Open Access

Demethylation of methylmercury and the enhanced production of formaldehyde in mouse liver

Uchikawa, T., Kanno, T., Maruyama, I., Mori, N., Yasutake, A., Ishii, Y. & Yamada, H., Jan 1 2016, In : Journal of Toxicological Sciences. 41, 4, p. 479-487 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay

Sakamoto, S., Kohno, T., Shimizu, K., Tanaka, H. & Morimoto, S., May 1 2016, In : Planta medica. 82, 8, p. 747-751 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Development of pH-Responsive BODIPY Probes for Staining Late Endosome in Live Cells

Miao, F., Uchinomiya, S., Ni, Y., Chang, Y. T. & Wu, J., Nov 1 2016, In : ChemPlusChem. 81, 11, p. 1209-1215 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Diacylglycerol kinase ζ generates dipalmitoyl-phosphatidic acid species during neuroblastoma cell differentiation

Mizuno, S., Kado, S., Goto, K., Takahashi, D. & Sakane, F., Dec 2016, In : Biochemistry and Biophysics Reports. 8, p. 352-359 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Diethylenetriamine-Mediated Direct Cleavage of Unactivated Carbamates and Ureas

Noshita, M., Shimizu, Y., Morimoto, H. & Ohshima, T., Dec 2 2016, In : Organic Letters. 18, 23, p. 6062-6065 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Different roles of negative and positive components of the circadian clock in oncogene-induced neoplastic transformation

Katamune, C., Koyanagi, S., Shiromizu, S., Matsunaga, N., Shimba, S., Shibata, S. & Ohdo, S., May 13 2016, In : Journal of Biological Chemistry. 291, 20, p. 10541-10550 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
40 Citations (Scopus)

DNA cleavage at the AP site via β-elimination mediated by the AP site-binding ligands

Abe, Y. S. & Sasaki, S., Feb 15 2016, In : Bioorganic and Medicinal Chemistry. 24, 4, p. 910-914 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Masuda, T., Ozono, Y., Mikuriya, S., Kohro, Y., Tozaki-Saitoh, H., Iwatsuki, K., Uneyama, H., Ichikawa, R., Salter, M. W., Tsuda, M. & Inoue, K., Aug 12 2016, In : Nature communications. 7, 12529.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Duloxetine inhibits microglial P2X4 receptor function and alleviates neuropathic pain after peripheral nerve injury

Yamashita, T., Yamamoto, S., Zhang, J., Kometani, M., Tomiyama, D., Kohno, K., Tozaki-Saitoh, H., Inoue, K. & Tsuda, M., Oct 2016, In : PloS one. 11, 10, e0165189.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Dysfunction of glutamate receptors in microglia may cause neurodegeneration

Noda, M., Apr 1 2016, In : Current Alzheimer Research. 13, 4, p. 381-386 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effect of linker length between variable domains of single chain variable fragment antibody against daidzin on its reactivity

Yusakul, G., Sakamoto, S., Pongkitwitoon, B., Tanaka, H. & Morimoto, S., Jan 1 2016, In : Bioscience, Biotechnology and Biochemistry. 80, 7, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme*

Abe, Y., Kubota, M., Takazaki, S., Ito, Y., Yamamoto, H., Kang, D., Ueda, T. & Imoto, T., Sep 1 2016, In : Protein Science. p. 1637-1647 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of 8-halo-7-deaza-2′-deoxyguanosine triphosphate on DNA synthesis by DNA polymerases and cell proliferation

Yin, Y., Sasaki, S. & Taniguchi, Y., Jan 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 16, p. 3856-3861 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects on deaf patients of medication education by pharmacists

Hyoguchi, N., Kobayashi, D., Kubota, T. & Shimazoe, T., Oct 1 2016, In : Journal of Deaf Studies and Deaf Education. 21, 4, p. 416-421 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
5 Citations (Scopus)

Efficient thymidine-selective DNA interstrand photo-activated crosslinking by the 6-thioguanine connected via an ethylene-linker to the 2′-deoxyribose unit

Nishioka, T., Oshiro, I., Onizuka, K., Taniguchi, Y. & Sasaki, S., Jan 1 2016, In : Chemical and Pharmaceutical Bulletin. 64, 9, p. 1315-1320 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Emission characteristics of paliperidone from invega™ tablets in one-dose packages and the evaluation of patients

Kito, H., Ishida, Y., Kunimi, M., Morooka, Y., Hirowatari, T., Akamine, T., Hashimoto, H., Koyanagi, S., Ohdo, S. & Kamimura, H., Jan 1 2016, In : Japanese Pharmacology and Therapeutics. 44, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

Enantioselective determination of citrulline and ornithine in the urine of D-amino acid oxidase deficient mice using a two-dimensional high-performance liquid chromatographic system

Koga, R., Miyoshi, Y., Sato, Y., Mita, M., Konno, R., Lindner, W. & Hamase, K., Oct 7 2016, In : Journal of Chromatography A. 1467, p. 312-317 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Ephedrae herba stimulates hepatocyte growth factor-induced MET endocytosis and downregulation via early/late endocytic pathways in gefitinib-resistant human lung cancer cells

Nishimura, Y., Hyuga, S., Takiguchi, S., Hyuga, M., Itoh, K. & Hanawa, T., May 2016, In : International journal of oncology. 48, 5, p. 1895-1906 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Fluorescence probes to detect lipid-derived radicals

Yamada, K. I., Mito, F., Matsuoka, Y., Ide, S., Shikimachi, K., Fujiki, A., Kusakabe, D., Ishida, Y., Enoki, M., Tada, A., Ariyoshi, M., Yamasaki, T. & Yamato, M., Aug 1 2016, In : Nature Chemical Biology. 12, 8, p. 608-613 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

Koyanagi, S., Kusunose, N., Taniguchi, M., Akamine, T., Kanado, Y., Ozono, Y., Masuda, T., Kohro, Y., Matsunaga, N., Tsuda, M., Salter, M. W., Inoue, K. & Ohdo, S., Oct 14 2016, In : Nature communications. 7, 13102.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction

Fukuda, H., Ito, S., Watari, K., Mogi, C., Arisawa, M., Okajima, F., Kurose, H. & Shuto, S., May 12 2016, In : ACS Medicinal Chemistry Letters. 7, 5, p. 493-497 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., Oct 2016, In : PloS one. 11, 10, e0165473.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi

Sakamoto, S., Kikkawa, N., Kohno, T., Shimizu, K., Tanaka, H. & Morimoto, S., Oct 1 2016, In : Fitoterapia. 114, p. 51-55 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice

Watari, K., Shibata, T., Nabeshima, H., Shinoda, A., Fukunaga, Y., Kawahara, A., Karasuyama, K., Fukushi, J. I., Iwamoto, Y., Kuwano, M. & Ono, M., Jan 18 2016, In : Scientific reports. 6, 19470.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Improved quality of life in patients with no-option critical limb ischemia undergoing gene therapy with DVC1-0101

Matsumoto, T., Tanaka, M., Yoshiya, K., Yoshiga, R., Matsubara, Y., Horiuchi-Yoshida, K., Yonemitsu, Y. & Maehara, Y., Jul 15 2016, In : Scientific reports. 6, 30035.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease

Matsunaga, N., Ikeda, E., Kakimoto, K., Watanabe, M., Shindo, N., Tsuruta, A., Ikeyama, H., Hamamura, K., Higashi, K., Yamashita, T., Kondo, H., Yoshida, Y., Matsuda, M., Ogino, T., Tokushige, K., Itcho, K., Furuichi, Y., Nakao, T., Yasuda, K., Doi, A. & 7 others, Amamoto, T., Aramaki, H., Tsuda, M., Inoue, K., Ojida, A., Koyanagi, S. & Ohdo, S., Nov 1 2016, In : EBioMedicine. 13, p. 262-273 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock

Nakamura, Y., Nakano, N., Ishimaru, K., Ando, N., Katoh, R., Suzuki-Inoue, K., Koyanagki, S., Ogawa, H., Okumura, K., Shibata, S. & Nakao, A., Apr 1 2016, In : Journal of Allergy and Clinical Immunology. 137, 4, p. 1226-1235 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Inhibitory Effect of 8-Halogenated 7-Deaza-2′-deoxyguanosine Triphosphates on Human 8-Oxo-2′-deoxyguanosine Triphosphatase, hMTH1, Activities

Yin, Y., Sasaki, S. & Taniguchi, Y., Apr 1 2016, In : ChemBioChem. 17, 7, p. 566-569 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota

Sasabe, J., Miyoshi, Y., Rakoff-Nahoum, S., Zhang, T., Mita, M., Davis, B. M., Hamase, K. & Waldor, M. K., Jul 25 2016, In : Nature Microbiology. 1, 16125.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Intracellular delivery of chemical probes using a glutathione-responsive traceless tag

Aoyama, E., Fuchida, H., Oshikawa, Y., Uchinomiya, S. & Ojida, A., Jan 1 2016, In : Chemical Communications. 52, 49, p. 7715-7718 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Introduction of an N-glycosylation site into UDP-glucuronosyltransferase 2B3 alters its sensitivity to cytochrome P450 3A1-dependent modulation

Nakamura, T., Yamaguchi, N., Miyauchi, Y., Takeda, T., Yamazoe, Y., Nagata, K., Mackenzie, P. I., Yamada, H. & Ishii, Y., Nov 14 2016, In : Frontiers in Pharmacology. 7, NOV, 427.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Isomeric iodinated analogs of nimesulide: Synthesis, physicochemical characterization, cyclooxygenase-2 inhibitory activity, and transport across Caco-2 cells

Yamamoto, Y., Arai, J., Hisa, T., Saito, Y., Mukai, T., Ohshima, T., Maeda, M. & Yamamoto, F., Jan 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 16, p. 3727-3733 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Long inverted repeat transiently stalls DNA replication by forming hairpin structures on both leading and lagging strands

Lai, P. J., Lim, C. T., Le, H. P., Katayama, T., Leach, D. R. F., Furukohri, A. & Maki, H., Feb 1 2016, In : Genes to Cells. 21, 2, p. 136-145 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Lung adenocarcinoma may be a more susceptive subtype to a dendritic cell-based cancer vaccine than other subtypes of non-small cell lung cancers: a multicenter retrospective analysis

Takahashi, H., Shimodaira, S., Ogasawara, M., Ota, S., Kobayashi, M., Abe, H., Morita, Y., Nagai, K., Tsujitani, S., Okamoto, M., Suzuki, Y., Nakanishi, Y., Yonemitsu, Y. & for the DC Vaccine Study Group at the Japanese Society of Immunotherapy, T. DC. V. S. G. A. T. J. S. O. I., Sep 1 2016, In : Cancer Immunology, Immunotherapy. 65, 9, p. 1099-1111 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
41 Citations (Scopus)

Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells

Unoki, T., Abiko, Y., Toyama, T., Uehara, T., Tsuboi, K., Nishida, M., Kaji, T. & Kumagai, Y., Jun 30 2016, In : Scientific reports. 6, 28944.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Microglia in the spinal cord and neuropathic pain

Tsuda, M., Jan 1 2016, In : Journal of Diabetes Investigation. 7, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae

Shiroishi, M., Moriya, M. & Ueda, T., Oct 1 2016, In : Protein Science. p. 1863-1872 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Near-atomic structural model for bacterial DNA replication initiation complex and its functional insights

Shimizu, M., Noguchi, Y., Sakiyama, Y., Kawakami, H., Katayama, T. & Takada, S., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8021-E8030

Research output: Contribution to journalArticle

17 Citations (Scopus)

New pregnane and phenolic glycosides from Solenostemma argel

Ounaissia, K., Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delemasure, S., Dutartre, P., Smati, D. & Lacaille-Dubois, M. A., Oct 1 2016, In : Fitoterapia. 114, p. 98-104 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation

Aizawa, M., Sugimoto, N., Watanabe, S., Yoshida, K. & Fujita, M., Nov 1 2016, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 11, p. 2739-2748 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Oleanolic acid and hederagenin glycosides from Weigela stelzneri

Rezgui, A., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delemasure, S., Dutartre, P. & Lacaille-Dubois, M. A., Mar 1 2016, In : Phytochemistry. 123, p. 40-47 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
17 Citations (Scopus)

Participation of D-serine in the development and reproduction of the silkworm Bombyx mori

Tanigawa, M., Suzuki, C., Niwano, K., Kanekatsu, R., Tanaka, H., Horiike, K., Hamase, K. & Nagata, Y., Apr 1 2016, In : Journal of insect physiology. 87, p. 20-29 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)