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2019

Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis

Inoue, H., Tamaki, Y., Kashihara, Y., Muraki, S., Kakara, M., Hirota, T. & Ieiri, I., Feb 2019, In : British journal of clinical pharmacology. 85, 2, p. 393-402 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling

Tabata, S., Jevtic, M., Kurashige, N., Fuchida, H., Kido, M., Tani, K., Zenmyo, N., Uchinomiya, S., Harada, H., Itakura, M., Hamachi, I., Shigemoto, R. & Ojida, A., Dec 20 2019, In : iScience. 22, p. 256-268 13 p.

Research output: Contribution to journalArticle

Open Access

Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory

Li, R. S., Fukumori, R., Takeda, T., Song, Y., Morimoto, S., Kikura-Hanajiri, R., Yamaguchi, T., Watanabe, K., Aritake, K., Tanaka, Y., Yamada, H., Yamamoto, T. & Ishii, Y., Jul 3 2019, In : Scientific reports. 9, 1, 1 p., 9621.

Research output: Contribution to journalArticle

Open Access

Elucidation of N1-methyladenosine as a potential surrogate biomarker for drug interaction studies involving renal organic cation transporters

Miyake, T., Mizuno, T., Takehara, I., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Watanabe, N., Kato, Y., Ieiri, I., Maeda, K., Ando, O. & Kusuhara, H., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 11, p. 1270-1280 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis

Jiang, Y., Lu, S., Hirai, G., Kato, T., Onaka, H. & Kakeya, H., Apr 11 2019, In : Tetrahedron Letters. 60, 15, p. 1072-1074 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
2 Citations (Scopus)

Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs

Kanado, Y., Tsurudome, Y., Omata, Y., Yasukochi, S., Kusunose, N., Akamine, T., Matsunaga, N., Koyanagi, S. & Ohdo, S., Nov 12 2019, In : Biochemical and Biophysical Research Communications. 519, 3, p. 613-619 7 p.

Research output: Contribution to journalArticle

Evaluation of the immunomodulatory effects of fucoidan derived from cladosiphon okamuranus tokida in mice

Tomori, M., Nagamine, T., Miyamoto, T. & Iha, M., Sep 24 2019, In : Marine Drugs. 17, 10, 547.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Igawa, T., Kishikawa, S., Abe, Y., Yamashita, T., Nagai, S., Shiroishi, M., Shinozaki, C., Tanaka, H., Tozaki-Saitoh, H., Tsuda, M., Inoue, K. & Ueda, T., Jan 25 2019, In : Purinergic Signalling.

Research output: Contribution to journalArticle

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Igawa, T., Kishikawa, S., Abe, Y., Yamashita, T., Nagai, S., Shiroishi, M., Shinozaki, C., Tanaka, H., Tozaki-Saitoh, H., Tsuda, M., Inoue, K. & Ueda, T., Mar 15 2019, In : Purinergic Signalling. 15, 1, p. 27-35 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Expression, Purification, and Characterization of Human Diacylglycerol Kinase ζ

Saito, T., Takahashi, D. & Sakane, F., Mar 19 2019, In : ACS Omega. 4, 3, p. 5540-5546 7 p.

Research output: Contribution to journalArticle

Open Access

Hederagenin glycosides from the fruits of Blighia unijugata

Petit, B., Mitaine-Offer, A. C., Delaude, C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., Jun 1 2019, In : Phytochemistry. 162, p. 260-269 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

Yasui, M., Menjyo, Y., Tokizane, K., Shiozawa, A., Tsuda, M., Inoue, K. & Kiyama, H., Mar 30 2019, In : Journal of neuroinflammation. 16, 1, 67.

Research output: Contribution to journalArticle

Open Access

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes

Nishiyama, K., Numaga-Tomita, T., Fujimoto, Y., Tanaka, T., Toyama, C., Nishimura, A., Yamashita, T., Naoya, M., Satoru, K., Azuma, Y. T., Ibuki, Y., Uchida, K., Ohdo, S. & Nishida, M., Sep 1 2019, In : British Journal of Pharmacology. 176, 18, p. 3723-3738 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., Dec 1 2019, In : Scientific reports. 9, 1, 16825.

Research output: Contribution to journalArticle

Open Access

Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy

Fujita, S., Hirota, T., Sakiyama, R., Baba, M. & Ieiri, I., Feb 2019, In : Journal of Neurochemistry. 148, 3, p. 373-385 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses

Suematsu, R., Miyamoto, T., Saijo, S., Yamasaki, S., Tada, Y., Yoshida, H. & Miyake, Y., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 16776-16788 13 p.

Research output: Contribution to journalArticle

Open Access

Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (Morus alba L.) callus cultures

Komaikul, J., Kitisripanya, T., Likhitwitayawuid, K., Sritularak, B., Tanaka, H. & Putalun, W., Oct 2 2019, In : Natural Product Research. 33, 19, p. 2762-2769 8 p.

Research output: Contribution to journalArticle

Induction of cell fusion/apoptosis in anaplastic thyroid carcinoma in orthotopic mouse model by urokinase-specific oncolytic Sendai virus

Miyagawa, Y., Araki, K., Yamashita, T., Tanaka, S., Tanaka, Y., Tomifuji, M., Ueda, Y., Yonemitsu, Y., Shimada, H. & Shiotani, A., Jan 1 2019, In : Head and Neck. 41, 9, p. 2873-2882 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., Mar 2019, In : Cancer Science. 110, 3, p. 1044-1053 10 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
1 Citation (Scopus)

Investigation of the endoplasmic reticulum localization of UDP-glucuronosyltransferase 2B7 with systematic deletion mutants

Miyauchi, Y., Kimura, S., Kimura, A., Kurohara, K., Hirota, Y., Fujimoto, K., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., May 1 2019, In : Molecular Pharmacology. 95, 5, p. 551-562 12 p.

Research output: Contribution to journalArticle

In Vivo Imaging of the Intra-and Extracellular Redox Status in Rat Stomach with Indomethacin-Induced Gastric Ulcers Using Overhauser-Enhanced Magnetic Resonance Imaging

Yasukawa, K., Shigemi, R., Kanbe, T., Mutsumoto, Y., Oda, F., Ichikawa, K., Yamada, K. I., Tun, X. & Utsumi, H., Jan 1 2019, In : Antioxidants and Redox Signaling. 30, 9, p. 1147-1161 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Isolation and identification of new anthraquinones from Rhamnus alaternus L and evaluation of their free radical scavenging activity

Ben Ammar, R., Miyamoto, T., Chekir-Ghedira, L., Ghedira, K. & Lacaille-Dubois, M. A., Jan 17 2019, In : Natural Product Research. 33, 2, p. 280-286 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Kinetics and localisation of haemin-induced lipoprotein oxidation

Morales, N. P., Chunephisal, P., Janprasit, J., Ishida, Y., Luechapudiporn, R. & Yamada, K. I., Oct 3 2019, In : Free Radical Research. 53, 9-10, p. 968-978 11 p.

Research output: Contribution to journalArticle

Macrophage centripetal migration drives spontaneous healing process after spinal cord injury

Kobayakawa, K., Ohkawa, Y., Yoshizaki, S., Tamaru, T., Saito, T., Kijima, K., Yokota, K., Hara, M., Kubota, K., Matsumoto, Y., Harimaya, K., Ozato, K., Masuda, T., Tsuda, M., Tamura, T., Inoue, K., Reggie Edgerton, V., Iwamoto, Y., Nakashima, Y. & Okada, S., May 15 2019, In : Science Advances. 5, 5, eaav5086.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Magnetic particles-based enzyme immunoassay for rapid determination of secoiridoid glycoside, amarogentin

Sakamoto, S., Wada, S., Morita, Y., Yamaguchi, T., Tanaka, H. & Morimoto, S., Mar 1 2019, In : Talanta. 194, p. 731-736 6 p.

Research output: Contribution to journalArticle

Mechanistic insight into catalytic aerobic chemoselective α-oxidation of acylpyrazoles

Taninokuchi, S., Yazaki, R. & Ohshima, T., Jan 1 2019, In : Heterocycles. 99, 2, p. 906-918 13 p.

Research output: Contribution to journalArticle

Open Access

Melanogenesis Inhibitors from the Endophytic Fungus Aspergillus amstelodami

Elsbaey, M., Sallam, A., El-Metwally, M., Nagata, M., Tanaka, C., Shimizu, K. & Miyamoto, T., Jan 1 2019, In : Chemistry and Biodiversity. 16, 8, e1900237.

Research output: Contribution to journalArticle

Microcurrent stimulation activates the circadian machinery in mice

Matsunaga, N., Yoshida, Y., Kitajou, N., Shiraishi, A., Kusunose, N., Koyanagi, S. & Ohdo, S., May 28 2019, In : Biochemical and Biophysical Research Communications. 513, 2, p. 293-299 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Microdosing clinical study to clarify pharmacokinetic and pharmacogenetic characteristics of atorvastatin in Japanese hypercholesterolemic patients

Lee, N., Maeda, K., Fukizawa, S., Ieiri, I., Tomaru, A., Akao, H., Takeda, K., Iwadare, M., Niwa, O., Masauji, T., Yamane, N., Kajinami, K., Kusuhara, H. & Sugiyama, Y., Dec 2019, In : Drug metabolism and pharmacokinetics. 34, 6, p. 387-395 9 p.

Research output: Contribution to journalArticle

Molecular Insight and Mode of Inhibition of α-Glucosidase and α-Amylase by Pahangensin A from Alpinia pahangensis Ridl.

Loo, K. Y., Leong, K. H., Sivasothy, Y., Ibrahim, H. & Awang, K., Jun 2019, In : Chemistry and Biodiversity. 16, 6, e1900032.

Research output: Contribution to journalArticle

Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene

Katamune, C., Koyanagi, S., Hashikawa, K. I., Kusunose, N., Akamine, T., Matsunaga, N. & Ohdo, S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 2, p. 547-558 12 p.

Research output: Contribution to journalArticle

Myristic acid specifically stabilizes diacylglycerol kinase δ protein in C2C12 skeletal muscle cells

Iwata, K., Sakai, H., Takahashi, D. & Sakane, F., Jul 2019, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 7, p. 1031-1038 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
1 Citation (Scopus)

New secondary metabolites from the mangrove endophytic fungus Aspergillus versicolor

Elsbaey, M., Tanaka, C. & Miyamoto, T., Aug 2019, In : Phytochemistry Letters. 32, p. 70-76 7 p.

Research output: Contribution to journalArticle

Non-invasive mapping of glutathione levels in mouse brains by in vivo electron paramagnetic resonance (EPR) imaging: Applied to a kindling mouse model

Emoto, M. C., Sato-Akaba, H., Matsuoka, Y., Yamada, K-I. & Fujii, H. G., Jan 18 2019, In : Neuroscience Letters. 690, p. 6-10 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nuciferols A and B: Novel sesquineolignans from Cocos nucifera

Elsbaey, M., Jie, B., Tanaka, C., Kato, H., Tsukamoto, S., Usui, K., Hirai, G. & Miyamoto, T., Aug 15 2019, In : Tetrahedron Letters. 60, 33, 150948.

Research output: Contribution to journalArticle

Optimized reaction pair of the Cyshis tag and Ni(II)-Nta probe for highly selective chemical labeling of membrane proteins

Zenmyo, N., Tokumaru, H., Uchinomiya, S., Fuchida, H., Tabata, S., Hamachi, I., Shigemoto, R. & Ojida, A., Jan 1 2019, In : Bulletin of the Chemical Society of Japan. 92, 5, p. 995-1000 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pancreatic carcinoma metastasis to a lung carcinoma lesion and pulmonary fibrotic regions, overtaking the stromal microenvironment: A case report

Nakaya, T., Sogabe, M., Yamamoto, S. I., Tsuji, K., Nakaya, M., Niki, T., Endo, S. & Tanaka, A., Jun 1 2019, In : Medicine (United States). 98, 24, e15888.

Research output: Contribution to journalArticle

Open Access

Pentacylic triterpenes from Lavandula coronopifolia: structure related inhibitory activity on α-glucosidase

Elsbaey, M., Mwakalukwa, R., Shimizu, K. & Miyamoto, T., Jan 1 2019, (Accepted/In press) In : Natural Product Research.

Research output: Contribution to journalArticle

Pharmacokinetics, Pharmacodynamics, and Safety of E6011, a Novel Humanized Antifractalkine (CX3CL1) Monoclonal Antibody: A Randomized, Double-Blind, Placebo-Controlled Single-Ascending-Dose Study

Tabuchi, H., Katsurabara, T., Mori, M., Aoyama, M., Obara, T., Yasuda, N., Kawano, T., Imai, T., Ieiri, I. & Kumagai, Y., May 2019, In : Journal of Clinical Pharmacology. 59, 5, p. 688-701 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Phytostilbenoid production in white mulberry (Morus alba L.) cell culture using bioreactors and simple deglycosylation by endogenous enzymatic hydrolysis

Komaikul, J., Kitisripanya, T., Inyai, C., Likhitwitayawuid, K., Sritularak, B., Tanaka, H. & Putalun, W., Apr 15 2019, In : In Vitro Cellular and Developmental Biology - Plant. 55, 2, p. 199-208 10 p.

Research output: Contribution to journalArticle

Population Pharmacokinetic Analysis of Phenytoin after Intravenous Administration of Fosphenytoin in Adult and Elderly Epileptic Patients

Higuchi, K., Yamashita, D., Kashihara, Y., Kakara, M., Hirota, T., Hirakawa, M. & Ieiri, I., Oct 1 2019, In : Therapeutic drug monitoring. 41, 5, p. 674-680 7 p.

Research output: Contribution to journalArticle

Preincubation format for a sensitive immunochromatographic assay for monocrotaline, a toxic pyrrolizidine alkaloid

Yusakul, G., Sakamoto, S., Chanpokapaiboon, K., Tanaka, H. & Morimoto, S., Nov 1 2019, In : Phytochemical Analysis. 30, 6, p. 653-660 8 p.

Research output: Contribution to journalArticle

Preparation of a highly specific single chain variable fragment antibody targeting miroestrol and its application in quality control of Pueraria candollei by enzyme-linked immunosorbent assay

Pongkitwitoon, B., Boonsnongcheep, P., Kitisripanya, T., Yusakul, G., Sakamoto, S., Tanaka, H., Morimoto, S. & Putalun, W., Nov 1 2019, In : Phytochemical Analysis. 30, 6, p. 600-608 9 p.

Research output: Contribution to journalArticle

Promoting patient care through communication training in a pre-clerkship pharmacy education course in Japan

Epp, D. A., Kubota, T., Yoshida, M., Kishimoto, J., Kobayashi, D. & Shimazoe, T., Jan 1 2019, In : American Journal of Pharmaceutical Education. 83, 5, p. 814-823 10 p., 6745.

Research output: Contribution to journalArticle