Research Output 1976 2020

Filter
Article
2017
7 Citations (Scopus)

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane

Rujas, E., Insausti, S., García-Porras, M., Sánchez-Eugenia, R., Tsumoto, K., Nieva, J. L. & Caaveiro, J. M. M., Apr 21 2017, In : Journal of Molecular Biology. 429, 8, p. 1213-1226 14 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
HIV-1
Membranes
AIDS Vaccines
Epitopes
13 Citations (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2017, In : EMBO Reports. 18, 1, p. 123-137 15 p.

Research output: Contribution to journalArticle

Glutamic Acid
Carcinogenesis
Ligases
Ubiquitin
WD40 Repeats
3 Citations (Scopus)

Haemolytic actinoporins interact with carbohydrates using their lipid-binding module

Tanaka, K., Caaveiro, J. M. M., Morante, K. & Tsumoto, K., Jan 1 2017, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 372, 1726, 20160216.

Research output: Contribution to journalArticle

toxins
Carbohydrates
carbohydrates
Polysaccharides
Lipids
1 Citation (Scopus)

Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a)

Homma, T., Akihara, R., Okano, S., Shichiri, M., Yoshida, Y., Yamada, K. I., Miyata, S., Nakajima, O. & Fujii, J., Feb 15 2017, In : Behavioural Brain Research. 319, p. 219-224 6 p.

Research output: Contribution to journalArticle

Ascorbic Acid
Aggression
Aldehyde Reductase
carbonyl reductase (NADPH)
Social Behavior
12 Citations (Scopus)

Heterogeneity of D-serine distribution in the human central nervous system

Suzuki, M., Imanishi, N., Mita, M., Hamase, K., Aiso, S. & Sasabe, J., May 1 2017, In : ASN Neuro. 9, 3

Research output: Contribution to journalArticle

Serine
Central Nervous System
Cerebrum
4 alpha-glucanotransferase
Neurophysiology
6 Citations (Scopus)

High ubiquitin-specific protease 44 expression induces DNA aneuploidy and provides independent prognostic information in gastric cancer

Nishimura, S., Oki, E., Ando, K., Iimori, M., Nakaji, Y., Nakashima, Y., Saeki, H., Oda, Y. & Maehara, Y., Jun 2017, In : Cancer Medicine. 6, 6, p. 1453-1464 12 p.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
Aneuploidy
Stomach Neoplasms
DNA
Chromosomal Instability
5 Citations (Scopus)

Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress

Wu, C. Y., Hsu, W. L., Tsai, M. H., Liang, J. L., Lu, J. H., Yen, C. J., Yu, H. S., Noda, M., Lu, C. Y., Chen, C. H., Yan, S. J. & Yoshioka, T., Dec 1 2017, In : Scientific reports. 7, 1, 3606.

Research output: Contribution to journalArticle

Oxidative stress
Disulfides
Hydrogen
Gases
Reactive Oxygen Species
1 Citation (Scopus)

Immunochromatographic determination of bacopaside I in biological samples

Sookying, S., Pekthong, D., Oo-puthinan, S., Phrompittayarat, W., Putalun, W., Tanaka, H., Xing, J., Zhan, Z., Khorana, N., Nuengchamnong, N. & Ingkaninan, K., Jan 1 2017, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1040, p. 60-66 7 p.

Research output: Contribution to journalArticle

Urine
Feces
Rats
Bacopa
Pharmacokinetics
27 Citations (Scopus)

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

Nagata, M., Izumi, Y., Ishikawa, E., Kiyotake, R., Doi, R., Iwai, S., Omahdi, Z., Yamaji, T., Miyamoto, T., Bamba, T. & Yamasaki, S., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. E3285-E3294

Research output: Contribution to journalArticle

Glucosylceramides
C-Type Lectins
Macrophages
Ligands
Dendritic Cells
12 Citations (Scopus)

Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide

Miyake, T., Mizuno, T., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Ieiri, I., Maeda, K. & Kusuhara, H., Sep 2017, In : Journal of Pharmaceutical Sciences. 106, 9, p. 2542-2550 9 p.

Research output: Contribution to journalArticle

Cations
Kidney
trimethyloxamine
Tetraethylammonium
Tissue Distribution

Lipid radicals cause light-induced retinal degeneration

Enoki, M., Shinto, S., Matsuoka, Y., Otsuka, A., Kaidzu, S., Tanito, M., Shibata, T., Uchida, K., Ohira, A., Yamato, M. & Yamada, K-I., Sep 20 2017, In : Chemical Communications.

Research output: Contribution to journalArticle

Lipids
Animals
Imaging techniques
Molecules
5 Citations (Scopus)

Lipid radicals cause light-induced retinal degeneration

Enoki, M., Shinto, S., Matsuoka, Y., Otsuka, A., Kaidzu, S., Tanito, M., Shibata, T., Uchida, K., Ohira, A., Yamato, M. & Yamada, K-I., Jan 1 2017, In : Chemical Communications. 53, 79, p. 10922-10925 4 p.

Research output: Contribution to journalArticle

Lipids
Animals
Imaging techniques
Molecules
8 Citations (Scopus)

Lipophilic triphenylphosphonium derivatives enhance radiation-induced cell killing via inhibition of mitochondrial energy metabolism in tumor cells

Yasui, H., Yamamoto, K., Suzuki, M., Sakai, Y., Bo, T., Nagane, M., Nishimura, E., Yamamori, T., Inanami, O., Yamada, K-I. & Yamasaki, T., Apr 1 2017, In : Cancer Letters. 390, p. 160-167 8 p.

Research output: Contribution to journalArticle

Energy Metabolism
Radiation
Neoplasms
Adenosine Triphosphate
Cations
5 Citations (Scopus)

Lycocasuarines A–C, Lycopodium alkaloids from Lycopodiastrum casuarinoides

Wang, L. L., Zhou, Z. B., Zhu, X. L., Yuan, F. Y., Miyamoto, T. & Pan, K., Dec 27 2017, In : Tetrahedron Letters. 58, 52, p. 4827-4831 5 p.

Research output: Contribution to journalArticle

Lycopodium
Alkaloids
Dilatation and Curettage
Spectroscopic analysis
X ray crystallography
5 Citations (Scopus)

Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes

Iribe, G., Kaihara, K., Yamaguchi, Y., Michio, N., Inoue, R. & Naruse, K., Nov 1 2017, In : Progress in Biophysics and Molecular Biology. 130, p. 315-322 8 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Reactive Oxygen Species
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Mitochondria
Organelles
3 Citations (Scopus)

Metabolomic profiling of brain tissues of mice chronically exposed to heroin

Li, R. S., Takeda, T., Ohshima, T., Yamada, H. & Ishii, Y., Feb 2017, In : Drug Metabolism and Pharmacokinetics. 32, 1, p. 108-111 4 p.

Research output: Contribution to journalArticle

Metabolomics
Heroin
Brain
Melatonin
Catecholamines
17 Citations (Scopus)

MiR30-GALNT1/2 axis-mediated glycosylation contributes to the increased secretion of inactive human prohormone for brain natriuretic peptide (proBNP) from failing hearts

Nakagawa, Y., Nishikimi, T., Kuwahara, K., Fujishima, A., Oka, S., Tsutamoto, T., Kinoshita, H., Nakao, K., Cho, K., Inazumi, H., Okamoto, H., Nishida, M., Kato, T., Fukushima, H., Yamashita, J. K., Wijnen, W. J., Creemers, E. E., Kangawa, K., Minamino, N., Nakao, K. & 1 others, Kimura, T., Jan 1 2017, In : Journal of the American Heart Association. 6, 2, e003601.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Glycosylation
Heart Failure
MicroRNAs
Cyclic GMP
9 Citations (Scopus)

Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent-induced mitotic arrest

Tsuda, Y., Iimori, M., Nakashima, Y., Nakanishi, R., Ando, K., Ohgaki, K., Kitao, H., Saeki, H., Oki, E. & Maehara, Y., Dec 1 2017, In : Scientific reports. 7, 1, 16762.

Research output: Contribution to journalArticle

Tubulin
Microtubules
eribulin
Aurora Kinase B
Endoreduplication
1 Citation (Scopus)

Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication

Nakanishi, R., Kitao, H., Kiniwa, M., Morodomi, Y., Iimori, M., Kurashige, J., Sugiyama, M., Nakashima, Y., Saeki, H., Oki, E. & Maehara, Y., Dec 1 2017, In : Scientific reports. 7, 1, 16969.

Research output: Contribution to journalArticle

Trifluridine
Colorectal Neoplasms
Blood Cells
Antibodies
DNA
3 Citations (Scopus)

Neuritogenic and neuroprotective constituents from Aquilaria crassna leaves

Supasuteekul, C., Tadtong, S., Putalun, W., Tanaka, H., Likhitwitayawuid, K., Tengamnuay, P. & Sritularak, B., Jun 2017, In : Journal of Food Biochemistry. 41, 3, e12365.

Research output: Contribution to journalArticle

Thymelaeaceae
neuroprotective effect
Neurons
leaves
Antipyretics
9 Citations (Scopus)

Nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors

Noda, M. & Kobayashi, A., Jan 1 2017, In : Journal of Physiological Sciences. 67, 1, p. 235-245 11 p.

Research output: Contribution to journalArticle

Microglia
Cholinergic Receptors
Nicotine
Protons
Nicotinic Receptors
8 Citations (Scopus)
Electron Spin Resonance Spectroscopy
Oxidation-Reduction
Glutathione
Paramagnetic resonance
Brain
3 Citations (Scopus)

Oleanane-type glycosides from Pittosporum tenuifolium “variegatum” and P. tenuifolium “gold star”

Rengifo Carrillo, M., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Pouységu, L., Quideau, S., Rosquete Porcar, C. & Lacaille-Dubois, M. A., Aug 1 2017, In : Phytochemistry. 140, p. 166-173 8 p.

Research output: Contribution to journalArticle

Rosales
Glycosides
Gold
gold
Stars
4 Citations (Scopus)
NFATC Transcription Factors
Cell signaling
CC Chemokines
Microglia
Adenosine Diphosphate
5 Citations (Scopus)

Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARα

Kanemitsu, T., Tsurudome, Y., Kusunose, N., Oda, M., Matsunaga, N., Koyanagi, S. & Ohdo, S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 52, p. 21397-21406 10 p.

Research output: Contribution to journalArticle

Orphan Nuclear Receptors
Peroxisome Proliferator-Activated Receptors
Xanthine Oxidase
Uric Acid
Bile Acids and Salts
5 Citations (Scopus)

Peripheral membrane interactions boost the engagement by an anti-HIV-1 broadly neutralizing antibody

Rujas, E., Caaveiro, J. M. M., Insausti, S., García-Porras, M., Tsumoto, K. & Nieva, J. L., Mar 31 2017, In : Journal of Biological Chemistry. 292, 13, p. 5571-5583 13 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
HIV-1
Membranes
Antibodies
Epitopes
7 Citations (Scopus)
Calcineurin
Type C Phospholipases
Osteoclasts
Bone
Up-Regulation
2 Citations (Scopus)

Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef

Nagata, M., Ishino, S., Yamagami, T., Simons, J. R., Kanai, T., Atomi, H. & Ishino, Y., Dec 1 2017, In : Scientific reports. 7, 1, 16949.

Research output: Contribution to journalArticle

Thermococcus
Proteins
Exonucleases
Archaea
DNA Repair

Purinergic signaling in cardiovascular system

Nishimura, A. & Nishida, M., Jan 1 2017, In : Folia Pharmacologica Japonica. 149, 2, p. 84-90 7 p.

Research output: Contribution to journalArticle

Uracil
Cardiovascular System
Adenosine
Signal Transduction
Hypertension
16 Citations (Scopus)

Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli

Sakiyama, Y., Kasho, K., Noguchi, Y., Kawakami, H. & Katayama, T., Dec 1 2017, In : Nucleic acids research. 45, 21, p. 12354-12373 20 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Escherichia coli
Binding Sites
Protein Subunits
Replication Origin
38 Citations (Scopus)

Reversible ratiometric detection of highly reactive hydropersulfides using a FRET-based dual emission fluorescent probe

Kawagoe, R., Takashima, I., Uchinomiya, S. & Ojida, A., Jan 1 2017, In : Chemical Science. 8, 2, p. 1134-1140 7 p.

Research output: Contribution to journalArticle

Fluorescent Dyes
Pyronine
Cells
Cell signaling
Mammals

Role of vasopressin V1a receptor in ∆9-tetrahydrocannabinol-induced cataleptic immobilization in mice

Egashira, N., Koushi, E., Myose, T., Tanoue, A., Mishima, K., Tsuchihashi, R., Kinjo, J., Tanaka, H., Morimoto, S. & Iwasaki, K., Dec 1 2017, In : Psychopharmacology. 234, 23-24, p. 3475-3483 9 p.

Research output: Contribution to journalArticle

Catalepsy
Vasopressin Receptors
Dronabinol
Immobilization
Knockout Mice
8 Citations (Scopus)

Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

Yoshimatsu, Y., Nakahara, T., Tanaka, K., Inagawa, Y., Narisawa-Saito, M., Yugawa, T., Ohno, S. I., Fujita, M., Nakagama, H. & Kiyono, T., Jul 2017, In : Cancer Science. 108, 7, p. 1303-1309 7 p.

Research output: Contribution to journalArticle

PDZ Domains
Keratinocytes
Neoplastic Cell Transformation
Carcinogenesis
Proteins
9 Citations (Scopus)

Self-Assembly Behavior of Emissive Urea Benzene Derivatives Enables Heat-Induced Accumulation in Tumor Tissue

Araki, T., Murayama, S., Usui, K., Shimada, T., Aoki, I. & Karasawa, S., Apr 12 2017, In : Nano Letters. 17, 4, p. 2397-2403 7 p.

Research output: Contribution to journalArticle

Benzene Derivatives
ureas
Urea
Self assembly
self assembly
20 Citations (Scopus)

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP

Kashihara, Y., Ieiri, I., Yoshikado, T., Maeda, K., Fukae, M., Kimura, M., Hirota, T., Matsuki, S., Irie, S., Izumi, N., Kusuhara, H. & Sugiyama, Y., Sep 2017, In : Journal of Pharmaceutical Sciences. 106, 9, p. 2688-2694 7 p.

Research output: Contribution to journalArticle

Citrus paradisi
Pharmacogenetics
Pharmacokinetics
Sulfasalazine
Pharmaceutical Preparations
9 Citations (Scopus)

Sodium periodate-mediated conjugation of harringtonine enabling the production of a highly specific monoclonal antibody, and the development of a sensitive quantitative analysis method

Sakamoto, S., Yusakul, G., Tsuneura, Y., Putalun, W., Usui, K., Miyamoto, T., Tanaka, H. & Morimoto, S., Apr 7 2017, In : Analyst. 142, 7, p. 1140-1148 9 p.

Research output: Contribution to journalArticle

Monoclonal antibodies
quantitative analysis
antibody
Monoclonal Antibodies
Sodium
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia

Species-dependent difference in the circadian rhythms of drug pharmacokinetics

Koyanagi, S. & Ohdo, S., Jan 1 2017, In : Drug Delivery System. 32, 5, p. 418-423 6 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Pharmacokinetics
Circadian Clocks
Pharmaceutical Preparations
Rodentia
20 Citations (Scopus)

Stimulation of adenosine A2B receptor inhibits endothelin-1-induced cardiac Fibroblast proliferation and α-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling pathway

Phosri, S., Arieyawong, A., Bunrukchai, K., Parichatikanond, W., Nishimura, A., Nishida, M. & Mangmool, S., Jun 30 2017, In : Frontiers in Pharmacology. 8, JUN, 428.

Research output: Contribution to journalArticle

Endothelin A Receptors
Phosphatidylinositol 3-Kinases
Adenosine
Endothelin-1
Smooth Muscle
6 Citations (Scopus)

Strongly Chemiluminescent Acridinium Esters under Neutral Conditions: Synthesis, Properties, Determination, and Theoretical Study

Nakazono, M., Oshikawa, Y., Nakamura, M., Kubota, H. & Nanbu, S., Mar 3 2017, In : Journal of Organic Chemistry. 82, 5, p. 2450-2461 12 p.

Research output: Contribution to journalArticle

Acridines
Chemiluminescence
Esters
Salts
Hydrogen Peroxide
6 Citations (Scopus)

Synchronized Chiral Induction between [5]Helicene–Spermine Ligand and B–Z DNA Transition

Kawara, K., Tsuji, G., Taniguchi, Y. & Sasaki, S., Jan 1 2017, In : Chemistry - A European Journal. 23, 8, p. 1763-1769 7 p.

Research output: Contribution to journalArticle

Chirality
DNA
Ligands
Z-Form DNA
B-Form DNA

Synthesis of 1-tetrasubstituted 2,2,2-trifluoroethylamine derivatives via palladium-catalyzed allylation of sp3 C–H bonds

Morisaki, K., Kondo, Y., Sawa, M., Morimoto, H. & Ohshima, T., Jan 1 2017, In : Chemical and Pharmaceutical Bulletin. 65, 11, p. 1089-1092 4 p.

Research output: Contribution to journalArticle

Allylation
Palladium
Derivatives
Carbon
Imines
2 Citations (Scopus)

Synthesis of polyunsaturated fatty acid-containing glucuronosyl-diacylglycerol through direct glycosylation

Wang, Q., Kuramoto, Y., Okazaki, Y., Ota, E., Morita, M., Hirai, G., Saito, K. & Sodeoka, M., Jan 1 2017, In : Tetrahedron Letters. 58, 30, p. 2915-2918 4 p.

Research output: Contribution to journalArticle

Glycosylation
Glycerides
Glycolipids
Glucuronides
Unsaturated Fatty Acids
5 Citations (Scopus)

Synthesis of the Right‐Side Structure of Type B Physalins

Morita, M., Kojima, S., Ohkubo, M., Koshino, H., Hashizume, D., Hirai, G., Maruoka, K. & Sodeoka, M., 2017, In : Israel Journal of Chemistry. 57, 3-4, p. 309-318 10 p.

Research output: Contribution to journalArticle

Methylation
Kinetics
physalin B
14 Citations (Scopus)

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

Murakami, Y., Sonoda, K., Abe, H., Watari, K., Kusakabe, D., Azuma, K., Kawahara, A., Akiba, J., Oneyama, C., Pachter, J. A., Sakai, K., Nishio, K., Kuwano, M. & Ono, M., Jan 1 2017, In : Oncotarget. 8, 41, p. 70736-70751 16 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Focal Adhesion Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Lung Neoplasms
Phosphotransferases
8 Citations (Scopus)

The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis

Nagata, M., Ishino, S., Yamagami, T., Ogino, H., Simons, J. R., Kanai, T., Atomi, H. & Ishino, Y., Oct 1 2017, In : Nucleic acids research. 45, 18, p. 10693-10705 13 p.

Research output: Contribution to journalArticle

Thermococcus
DNA Replication
Maintenance
Proteins
DNA Helicases

The current status of nursing professionalism among nursing faculty in Japan

Tanaka, M., Taketomi, K., Yonemitsu, Y. & Kawamoto, R., Jan 1 2017, In : Journal of Nursing Research. 25, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

Nursing Faculties
Japan
Nursing
Nursing Education
Equipment and Supplies
4 Citations (Scopus)

The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide

Paudel, M. K., Sakamoto, S., Van Huy, L., Tanaka, H., Miyamoto, T. & Morimoto, S., Jun 10 2017, In : Journal of Biotechnology. 251, p. 47-52 6 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Glucuronides
Antibodies
Peptides
Assays
5 Citations (Scopus)

The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction

Nagasaka, A., Mogi, C., Ono, H., Nishi, T., Horii, Y., Ohba, Y., Sato, K., Nakaya, M., Okajima, F. & Kurose, H., Dec 1 2017, In : Scientific reports. 7, 1, 7812.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Protons
Cell Death
Myocardial Infarction
T-Lymphocytes
2 Citations (Scopus)

The structure of an archaeal β-glucosaminidase provides insight into glycoside hydrolase evolution

Mine, S., Watanabe, M., Kamachi, S., Abe, Y. & Ueda, T., Mar 24 2017, In : Journal of Biological Chemistry. 292, 12, p. 4996-5006 11 p.

Research output: Contribution to journalArticle

Hexosaminidases
Glycoside Hydrolases
Galactosidases
Glucosamine
Catalytic Domain