Hepatology & Pancreatology

Research Output 1986 2019

1986
7 Citations (Scopus)

Primary ciliary dyskinesia with transverse colon carcinoma

Yoshida, J., Tsuneyoshi, M., Nakamura, K., Murakami, T. & Akamine, Y., Jan 1 1986, In : American Journal of Clinical Pathology. 85, 1, p. 101-104 4 p.

Research output: Contribution to journalArticle

Kartagener Syndrome
Situs Inversus
Transverse Colon
Carcinoma
Dyneins
1990
39 Citations (Scopus)

Intracellular distribution of the envelope glycoprotein of human immunodeficiency virus and its role in the production of cytopathic effect in CD4+ and CD4- human cell lines

Koga, Y., Sasaki, M., Nakamura, K., Kimura, G. & Nomoto, K., 1990, In : Journal of Virology. 64, 10, p. 4661-4671 11 p.

Research output: Contribution to journalArticle

cytopathogenicity
human cell lines
Human immunodeficiency virus
Nuclear Pore
glycoproteins

Non-specific esterase positive neutrophils in a case of refractory anemia with excess of blasts

Nakamura, K., Ideguchi, H., Okajima, T. & Kato, K., Mar 1 1990, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 31, 3, p. 386-390 5 p.

Research output: Contribution to journalArticle

Refractory Anemia with Excess of Blasts
Carboxylesterase
Neutrophils
Bone Marrow
Pancytopenia
12 Citations (Scopus)

PERIOPERATIVE BLOOD TRANSFUSION AND GASTRIC CANCER: ADVERSE EFFECTS OR UNFAVOURABLE CONDITIONS OF PRETREATMENT?

Yamaguchi, K., Tokui, N., Maeda, S., Kominami, T., Nakamura, K. & Kitamura, K., Jan 1 1990, In : Australian and New Zealand Journal of Surgery. 60, 10, p. 765-772 8 p.

Research output: Contribution to journalArticle

Blood Transfusion
Stomach Neoplasms
Japan
Regression Analysis
1991
21 Citations (Scopus)

Accumulation of p60 lck in HTLV‐I‐transformed T Cell Lines Detected by an Anti‐Lck Monoclonal Antibody, MOL 171

Moroi, Y., Koga, Y., Nakamura, K., Ohtsu, M., Kimura, G. & Nomoto, K., Jan 1 1991, In : Japanese Journal of Cancer Research. 82, 8, p. 909-915 7 p.

Research output: Contribution to journalArticle

Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Monoclonal Antibodies
T-Lymphocytes
Cell Line
Complementary DNA
8 Citations (Scopus)

Differential expression of two lck transcripts directed from the distinct promoters in HTLV‐I+ and HTLV‐I T‐cells

Nakamura, K., Koga, Y., Yoshida, H., Kimura, G. & Nomoto, K., Jan 1 1991, In : International Journal of Cancer. 48, 5, p. 789-793 5 p.

Research output: Contribution to journalArticle

Cell Line
Messenger RNA
Untranslated Regions
Genes
Tyrosine
1992
7 Citations (Scopus)

Alteration of bile acid metabolism in two‐thirds hepatectomized rat

Nakamura, K., ICHIMIYA, HITOSHI. & NAKAYAMA, FUMIO., Jan 1 1992, In : Journal of Gastroenterology and Hepatology. 7, 2, p. 121-127 7 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Hepatectomy
Cholic Acid
Liver
Weights and Measures
7 Citations (Scopus)

A lymphocyte-specific protein tyrosine kinase, p56lck, regulates the PMA-induced internalization of CD4

Yoshida, H., Koga, Y., Nakamura, K., Kimura, G. & Nomoto, K., Nov 17 1992, In : BBA - Molecular Cell Research. 1137, 3, p. 321-330 10 p.

Research output: Contribution to journalReview article

CD4 Antigens
Protein-Tyrosine Kinases
Lymphocytes
T-Cell Antigen Receptor
CD27 Antigens
1993
8 Citations (Scopus)

Confirmation of Dieulafoy's Vascular Lesion by Endoscopic Ultrasonography in Three Cases

AKAHOSHI, K., CHIJIIWA, Y., MISAWA, T., AYUKAWA, K., Nakamura, K., JIMI, M., AKAMINE, Y. & NAWATA, H., Jan 1 1993, In : Digestive Endoscopy. 5, 4, p. 383-390 8 p.

Research output: Contribution to journalArticle

Endosonography
Blood Vessels
Endoscopic Hemostasis
Hemorrhage
Gastric Stump
1 Citation (Scopus)

Induction of Interleukin 2-Responsiveness in Thymocytes of the Transgenic Mice Carrying Ick -Transgene

Moroi, Y., Koga, Y., Nakamura, K., Nomoto, K., Ohtsu, M. & Kimura, G., Jan 1 1993, In : MICROBIOLOGY and IMMUNOLOGY. 37, 5, p. 774-777 4 p.

Research output: Contribution to journalArticle

Thymocytes
Transgenes
Transgenic Mice
Interleukin-2
Phosphotransferases
1994

A case oa juvenile polyps associated with unclassified colitis

Nakamura, K., Maruoka, A., Okabe, H., Akiho, H., Yasuda, D., Tanaka, M., Harada, N., Chijiiwa, Y. & Nawata, H., 1994, In : Japanese Journal of Gastroenterology. 91, 3, p. 335-339 5 p.

Research output: Contribution to journalArticle

Colonic Polyps
Colitis
Colonoscopy
Polyps
54 Citations (Scopus)

Efficient degradation of trichloroethylene by a hybrid aromatic ring dioxygenase

Furukawa, K., Hirose, J., Hayashida, S. & Nakamura, K., Jan 1 1994, In : Journal of bacteriology. 176, 7, p. 2121-2123 3 p.

Research output: Contribution to journalComment/debate

Trichloroethylene
Dioxygenases
Genes
Ferredoxins
Operon
67 Citations (Scopus)

Gene replacement of the p53 gene with the lacz gene in mouse embryonic stem-cells and mice by using two steps of homologous recombination

Gondo, Y., Nakamura, K., Nakao, K., Sasaoka, T., Ito, K., Kimura, M. & Katsuki, M., Jul 29 1994, In : Biochemical and Biophysical Research Communications. 202, 2, p. 830-837 8 p.

Research output: Contribution to journalArticle

Lac Operon
Homologous Recombination
p53 Genes
Embryonic Stem Cells
Stem cells
9 Citations (Scopus)

Inhibition of the T-cell receptor-mediated signal transduction by microinjection of anti-Lck monoclonal antibody into T-cells

Nakamura, K., Koga, Y., Yoshida, H., Tanaka, K., Sasaki, M., Kimura, G. & Nomoto, K., Dec 30 1994, In : BBA - Molecular Cell Research. 1224, 3, p. 495-505 11 p.

Research output: Contribution to journalArticle

Microinjections
T-Cell Antigen Receptor
Signal Transduction
Monoclonal Antibodies
T-Lymphocytes
22 Citations (Scopus)

The difference in gp160 and gp120 of HIV type 1 in the induction of CD4 downregulation preceding single-cell killing

Koga, Y., Nakamura, K., Sasaki, M., Kimura, G. & Nomoto, K., May 15 1994, In : Virology. 201, 1, p. 137-141 5 p., 71274.

Research output: Contribution to journalArticle

HIV Envelope Protein gp160
HIV Envelope Protein gp120
HIV-1
Down-Regulation
Clone Cells
1995
25 Citations (Scopus)

Two endothelin receptors (ETA and ETB) expressed on circular smooth muscle cells of guinea pig cecum

Okabe, H., Chijiiwa, Y., Nakamura, K., Yoshinaga, M., Akiho, H., Harada, N. & Nawata, H., Jan 1 1995, In : Gastroenterology. 108, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Cecum
Endothelin-1
Smooth Muscle Myocytes
Guinea Pigs
1996
13 Citations (Scopus)

Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens

Nakamura, K., Chijiiwa, Y. & Nawata, H., Jan 1 1996, In : European Journal of Cancer Part A. 32, 8, p. 1401-1407 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Colon
Neoplasm Metastasis
Carcinoma
Cell Line
35 Citations (Scopus)

Traumatic rupture of hepatic hemangioma

Hotokezaka, M., Kojima, M., Nakamura, K., Hidaka, H., Nakano, Y., Tsuneyoshi, M. & Jimi, M., Jul 1 1996, In : Journal of Clinical Gastroenterology. 23, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

Hemangioma
Rupture
Traffic Accidents
Liver
Wounds and Injuries
1997
2 Citations (Scopus)

Expression of the placenta-specific, 100 kDa ras GTPase activating protein in several human cancer cell lines and normal human tissues

Araki, Y., Nakamura, K., Chijiiwa, Y. & Nawata, H., Nov 3 1997, In : Molecular and Cellular Biochemistry. 175, 1-2, p. 195-204 10 p.

Research output: Contribution to journalArticle

ras GTPase-Activating Proteins
Placenta
Cells
Tissue
Cell Line
1998
36 Citations (Scopus)

Adrenocortical and gonadal expression of the mammalian Ftz-F1 gene encoding Ad4BP/SF-1 is independent of pituitary control

Nomura, M., Kawabe, K., Matsushita, S., Oka, S., Hatano, O., Harada, N., Nawata, H. & Morohashi, K-I., Jan 1 1998, In : Journal of Biochemistry. 124, 1, p. 217-224 8 p.

Research output: Contribution to journalArticle

Gene encoding
Rats
Genes
Gonads
Tropics
12 Citations (Scopus)

A new approach to Pneumatosis cystoides intestinalis by target air- enema CT

Ihara, E., Harada, N., Motomura, S. & Chijiiwa, Y., Jul 1 1998, In : American Journal of Gastroenterology. 93, 7, p. 1163-1164 2 p.

Research output: Contribution to journalArticle

Pneumatosis Cystoides Intestinalis
Ascending Colon
Enema
Gases
Air
4 Citations (Scopus)

Complete response of early gastric cancer to uracil and tegafur

Akahoshi, K., Chijiiwa, Y., Hamada, S., Hara, K., Nakamura, K., Nawata, H. & Matsui, N., Dec 1 1998, In : Journal of Gastroenterology. 33, 6, p. 864-867 4 p.

Research output: Contribution to journalArticle

Tegafur
Uracil
Stomach Neoplasms
Endoscopy
Endosonography

Endosonographic probe-guided endoscopic resection of focal lymphoid hyperplasia of the rectum

Watabe, R., Araki, Y., Motomura, Y., Kubo, H., Ochiai, T., Hamada, S., Nakamura, K., Chijiiwa, Y., Nawata, H. & Matsui, N., Jan 1 1998, In : Journal of Clinical Gastroenterology. 26, 4, p. 348-350 3 p.

Research output: Contribution to journalArticle

Rectal Diseases
Endosonography
Lymphoid Tissue
Rectum
Endoscopy
16 Citations (Scopus)

Increased mRNA expression of a novel prostacyclin-stimulating factor in human colon cancer

Umeda, F., Ono, Y., Sekiguchi, N., Hashimoto, T., Masakado, M., Nakamura, K., Chijiiwa, Y. & Nawata, H., Apr 1 1998, In : Journal of Gastroenterology. 33, 2, p. 213-217 5 p.

Research output: Contribution to journalArticle

Epoprostenol
Colonic Neoplasms
Colon
Messenger RNA
Culture Media
9 Citations (Scopus)

Liver failure caused by hepatic angiodysplasia in hereditary hemorrhagic telangiectasia

Mukasa, C., Nakamura, K., Chijiiwa, Y., Sakai, H. & Nawata, H., Jan 1 1998, In : American Journal of Gastroenterology. 93, 3, p. 471-473 3 p.

Research output: Contribution to journalArticle

Angiodysplasia
Hereditary Hemorrhagic Telangiectasia
Liver Failure
Liver
Liver Diseases
4 Citations (Scopus)

Preoperative colonoscopic diagnosis of minute appendicular adenoma: Report of a case

Itaba, S., Akahoshi, K., Araki, Y., Nakamura, K., Chijiiwa, Y., Ohata, Y., Shimura, H. & Nawata, H., Aug 11 1998, In : Endoscopy. 30, 5

Research output: Contribution to journalArticle

Appendiceal Neoplasms
Colonoscopy
Adenoma
Biopsy
1999

A case of intestinal malrotation with bleeding of the jejunal diverticula

Wan, H., Ochiai, T., Nakamura, K., Harada, N., Chijiiwa, Y., Nawata, H. & Sasaki, I., Nov 1 1999, In : Japanese Journal of Gastroenterology. 96, 11, p. 1276-1780 505 p.

Research output: Contribution to journalArticle

Jejunal Diseases
Gastrointestinal Hemorrhage
Diverticulum
Intestines
Hemorrhage
98 Citations (Scopus)

Dax-1 as one of the target genes of Ad4BP/SF-1

Kawabe, K., Shikayama, T., Tsuboi, H., Oka, S., Oba, K., Yanase, T., Nawata, H. & Morohashi, K-I., Jan 1 1999, In : Molecular Endocrinology. 13, 8, p. 1267-1284 18 p.

Research output: Contribution to journalArticle

Genes
Hypogonadism
Electrophoretic Mobility Shift Assay
Pituitary Gland
Cytoplasmic and Nuclear Receptors

Gastroduodenal intussusception secondary to a gastric leiomyoma resulting in an ulceration

Araki, Y., Shiratsuchi, M., Yasuda, O., Nakamura, K., Chijiiwa, Y. & Nawata, H., May 5 1999, In : Endoscopy. 31, 3

Research output: Contribution to journalArticle

Duodenal Diseases
Gastrointestinal Endoscopy
Intussusception
Leiomyoma
Ulcer
18 Citations (Scopus)

Thapsigargin-induced endothelium-dependent triphasic regulation of vascular tone in the porcine renal artery

Ihara, E., Hirano, K., Nishimura, J., Nawata, H. & Kanaide, H., Nov 9 1999, In : British Journal of Pharmacology. 128, 3, p. 689-699 11 p.

Research output: Contribution to journalArticle

Thapsigargin
Renal Artery
Endothelium
Blood Vessels
Swine
2000
20 Citations (Scopus)

A combination of cyclosporin-A (CsA) and interferon-gamma (INF-γ) iduces apoptosis in human gastric carcinoma cells

Morisaki, T., Matsunaga, H., Beppu, K., Ihara, E., Hirano, K., Kanaide, H., Mori, M. & Katano, M., Dec 27 2000, In : Anticancer research. 20, 5 B, p. 3363-3373 11 p.

Research output: Contribution to journalArticle

Cyclosporine
Interferon-gamma
Stomach
Apoptosis
Carcinoma
104 Citations (Scopus)

Activated Self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells

Kitani, A., Chua, K., Nakamura, K. & Strober, W., Jul 15 2000, In : Journal of Immunology. 165, 2, p. 691-702 12 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Clone Cells
Cytokines
T-Lymphocytes
Phenotype
4 Citations (Scopus)

Adrenocortical and gonadal differentiation regulated by transcription factors, Ad4BP/SF-1 (NR5A1) and Dax-I (NROB1)

Morohashi, K-I., Mukai, T., Kawabe, K., Suzuki, Mizusaki, H., Ishiharal, S., Umesono, K. & Kawajiri, K., Jan 1 2000, In : Endocrine Research. 26, 4, 1 p.

Research output: Contribution to journalArticle

Fushi Tarazu Transcription Factors
Steroidogenic Factor 1
Embryonic and Fetal Development
Repressor Proteins
Homeodomain Proteins
26 Citations (Scopus)

The mechanism of bradykinin-induced endothelium-dependent contraction and relaxation in the porcine interlobar renal artery

Ihara, E., Hirano, K., Derkach, D. N., Nishimura, J., Nawata, H. & Kanaide, H., Jan 1 2000, In : British Journal of Pharmacology. 129, 5, p. 943-952 10 p.

Research output: Contribution to journalArticle

Bradykinin
Renal Artery
Endothelium
Swine
Phenylephrine
36 Citations (Scopus)

Thrombin causes endothelium-dependent biphasic regulation of vascular tone in the porcine renal interlobar artery

Derkach, D. N., Ihara, E., Hirano, K., Nishimura, J., Takahashi, S. & Kanaide, H., Jan 1 2000, In : British Journal of Pharmacology. 131, 8, p. 1635-1642 8 p.

Research output: Contribution to journalArticle

Renal Artery
Thrombin
Endothelium
Blood Vessels
Swine
148 Citations (Scopus)
Interleukin-12 Receptors
Trinitrobenzenes
Intranasal Administration
Th1 Cells
Sulfonic Acids
2001
8 Citations (Scopus)

Ca2+ influx in the endothelial cells is required for the bradykinin-induced endothelium-dependent contraction in the porcine interlobar renal artery

Ihara, E., Derkach, D. N., Hirano, K., Nishimura, J., Nawata, H. & Kanaide, H., Aug 1 2001, In : Journal of Physiology. 534, 3, p. 701-711 11 p.

Research output: Contribution to journalArticle

Bradykinin
Renal Artery
Endothelium
Swine
Endothelial Cells
1246 Citations (Scopus)

Cell contact-dependent immunosuppression by CD4+CD25+ regulatory T cells is mediated by cell surface-bound transforming growth factor β

Nakamura, K., Kitani, A. & Strober, W., Sep 3 2001, In : Journal of Experimental Medicine. 194, 5, p. 629-644 16 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Regulatory T-Lymphocytes
Immunosuppression
T-Lymphocytes
CTLA-4 Antigen
2002
26 Citations (Scopus)

Mechanism of down-regulation of L-type Ca2+ channel in the proliferating smooth muscle cells of rat aorta

Ihara, E., Hirano, K., Hirano, M., Nishimura, J., Nawata, H. & Kanaide, H., Oct 16 2002, In : Journal of Cellular Biochemistry. 87, 2, p. 242-251 10 p.

Research output: Contribution to journalArticle

Depolarization
Bromodeoxyuridine
Volatile organic compounds
Smooth Muscle Myocytes
Muscle
37 Citations (Scopus)

PAR3β, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions

Kohjima, M., Noda, Y., Takeya, R., Saito, N., Takeuchi, K. & Sumimoto, H., Dec 1 2002, In : Biochemical and Biophysical Research Communications. 299, 4, p. 641-646 6 p.

Research output: Contribution to journalArticle

Cell Polarity
Tight Junctions
PDZ Domains
Proteins
Vertebrates
37 Citations (Scopus)

Sexually dimorphic expression of Dax-1 in the adrenal cortex

Mukai, T., Kusaka, M., Kawabe, K., Goto, K., Nawata, H., Fujieda, K. & Morohashi, K-I., Aug 7 2002, In : Genes to Cells. 7, 7, p. 717-729 13 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Genes
Androgen Receptors
Ligands
Hypogonadism
2003
3 Citations (Scopus)

A case of mediastinal pancreatic pseudocysts conservatively treated with somatostatin analogue

Akashi, T., Kawabe, K., Sakamoto, R., Gibo, J., Inoue, N., Kojima, M., Hisano, T., Arita, Y., Ito, T. & Nawata, H., Jun 1 2003, In : Japanese Journal of Gastroenterology. 100, 6, p. 713-718 6 p.

Research output: Contribution to journalArticle

Pancreatic Pseudocyst
Somatostatin
109 Citations (Scopus)

Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) gene transcription is regulated by Wnt4 in the female developing gonad

Mizusaki, H., Kawabe, K., Mukai, T., Ariyoshi, E., Kasahara, M., Yoshioka, H., Swain, A. & Morohashi, K-I., Apr 1 2003, In : Molecular Endocrinology. 17, 4, p. 507-519 13 p.

Research output: Contribution to journalArticle

X-Linked Genes
Chromosomes, Human, Pair 1
Gonads
Catenins
Steroidogenic Factor 1
19 Citations (Scopus)

Inhibition of interferon-γ-activated nuclear factor-κB by cyclosporin A: A possible mechanism for synergistic induction of apoptosis by interferon-γ and cyclosporin A in gastric carcinoma cells

Beppu, K., Morisaki, T., Matsunaga, H., Uchiyama, A., Ihara, E., Hirano, K., Kanaide, H., Tanaka, M. & Katano, M., Jun 13 2003, In : Biochemical and Biophysical Research Communications. 305, 4, p. 797-805 9 p.

Research output: Contribution to journalArticle

Interferons
Cyclosporine
Stomach
Cells
Apoptosis
65 Citations (Scopus)

Molecular Recognition in Dimerization between PB1 Domains

Noda, Y., Kohjima, M., Izaki, T., Ota, K., Yoshinaga, S., Inagaki, F., Ito, T. & Sumimoto, H., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43516-43524 9 p.

Research output: Contribution to journalArticle

Molecular recognition
Dimerization
Lysine
Proteins
Coulomb interactions
13 Citations (Scopus)

Novel germline mutation of the PTEN gene in a Japanese family with Cowden disease

Harada, N., Sugimura, T., Yoshimura, R., Motomura, S., Shirahama, S., Naramoto, J. I., Chijiiwa, Y., Nakamura, K., Ito, K. I. & Nawata, H., Jan 1 2003, In : Journal of gastroenterology. 38, 1, p. 87-91 5 p.

Research output: Contribution to journalArticle

Multiple Hamartoma Syndrome
Germ-Line Mutation
Exons
Palmoplantar Keratoderma
Terminator Codon
299 Citations (Scopus)

Novel Human Homologues of p47phox and p67phox Participate in Activation of Superoxide-producing NADPH Oxidases

Takeya, R., Yamamoto, N., Kami, K., Taura, M., Kohjima, M., Izaki, T., Nunoi, H. & Sumimoto, H., Jul 4 2003, In : Journal of Biological Chemistry. 278, 27, p. 25234-25246 13 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Superoxides
Chemical activation
src Homology Domains
Phagocytes
30 Citations (Scopus)

The PB1 domain and the PC motif-containing region are structurally similar protein binding modules

Yoshinaga, S., Kohjima, M., Ogura, K., Yokochi, M., Takeya, R., Ito, T., Sumimoto, H. & Inagaki, F., Oct 1 2003, In : EMBO Journal. 22, 19, p. 4888-4897 10 p.

Research output: Contribution to journalArticle

Ubiquitin
Protein Binding
Amino Acid Motifs
Saccharomycetales
Static Electricity
187 Citations (Scopus)

Transforming Growth Factor (TGF)-β1-producing Regulatory T Cells Induce Smad-mediated Interleukin 10 Secretion That Facilitates Coordinated Immunoregulatory Activity and Amelioration of TGF-β1-mediated Fibrosis

Kitani, A., Fuss, I., Nakamura, K., Kumaki, F., Usui, T. & Strober, W., Oct 20 2003, In : Journal of Experimental Medicine. 198, 8, p. 1179-1188 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Regulatory T-Lymphocytes
Interleukin-10
Fibrosis
Doxycycline
2004
3 Citations (Scopus)

Acute pancreatitis in the early stages of pregnancy associated with a PSTI gene mutation [1]

Inoue, N., Ito, T., Akashi, T., Kawabe, K., ono, T., Gibo, J., Arita, Y., Nawata, H. & Funakoshi, A., Oct 1 2004, In : Pancreas. 29, 3, p. 242-243 2 p.

Research output: Contribution to journalLetter