Research Output 1982 2019

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2019

A newly identified mutation in the PEX26 gene is associated with a milder form of Zellweger spectrum disorder

Tanaka, A. J., Okumoto, K., Tamura, S., Abe, Y., Hirsch, Y., Deng, L., Ekstein, J., Chung, W. K. & Fujiki, Y., Jan 1 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 1, a003483.

Research output: Contribution to journalArticle

Zellweger Syndrome
Peroxisomes
Fibroblasts
Mutation
Genes

CLEC3A, MMP7, and LCN2 as novel markers for predicting recurrence in resected G1 and G2 pancreatic neuroendocrine tumors

Miki, M., Oono, T., Fujimori, N., Takaoka, T., Kawabe, K., Miyasaka, Y., Ohtsuka, T., Saito, D., Nakamura, M., Ohkawa, Y., Oda, Y., Suyama, M., Ito, T. & Ogawa, Y., Jul 2019, In : Cancer Medicine. 8, 8, p. 3748-3760 13 p.

Research output: Contribution to journalArticle

Open Access
Matrix Metalloproteinase 7
Neuroendocrine Tumors
Recurrence
Genes
Neoplasms
1 Citation (Scopus)
Open Access
Nucleoside-Diphosphate Kinase
nucleoside-diphosphate kinase
diphosphates
nucleosides
Guanosine Triphosphate
1 Citation (Scopus)

Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis

Yoshitome, S., Aiba, Y., Yuge, M., Furuno, N., Watanabe, M. & Nakajo, N., Jul 12 2019, In : Biochemical and Biophysical Research Communications. 515, 1, p. 139-144 6 p.

Research output: Contribution to journalArticle

G2 Phase
Xenopus laevis
Cell Cycle
Phosphotransferases
Cells
2 Citations (Scopus)
Interneurons
Neuropil
Neurons
Brain
Mantodea
2018
6 Citations (Scopus)

Adherens junctions influence tight junction formation via changes in membrane lipid composition

Shigetomi, K., Ono, Y., Inai, T. & Ikenouchi, J., Jul 1 2018, In : Journal of Cell Biology. 217, 7, p. 2373-2381 9 p.

Research output: Contribution to journalArticle

Adherens Junctions
Tight Junctions
Membrane Lipids
Cholesterol
Catenins

A newly isolated Pex7-binding, atypical PTS2 protein P7BP2 is a novel dynein-type AAA+ protein

Niwa, H., Miyauchi-Nanri, Y., Okumoto, K., Mukai, S., Noi, K., Ogura, T. & Fujiki, Y., Dec 1 2018, In : Journal of Biochemistry. 164, 6, p. 437-447 11 p.

Research output: Contribution to journalArticle

Dyneins
Proteins
Peroxisomes
Sequence Alignment
Protein Transport
4 Citations (Scopus)

An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease

Hara-Kuge, S., Nishihara, T., Matsuda, T., Kitazono, T., Teramoto, T., Nagai, T. & Ishihara, T., Apr 1 2018, In : PloS one. 13, 4, e0194707.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Neurons
Fluorescence
calcium
Action Potentials
3 Citations (Scopus)

A phytochrome-B-mediated regulatory mechanism of phosphorus acquisition

Sakuraba, Y., Kanno, S., Mabuchi, A., Monda, K., Iba, K. & Yanagisawa, S., Dec 1 2018, In : Nature Plants. 4, 12, p. 1089-1101 13 p.

Research output: Contribution to journalArticle

phytochrome
phosphates
phosphorus
uptake mechanisms
Arabidopsis
13 Citations (Scopus)

Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation

Tsuchiya, M., Hara, Y., Okuda, M., Itoh, K., Nishioka, R., Shiomi, A., Nagao, K., Mori, M., Mori, Y., Ikenouchi, J., Suzuki, R., Tanaka, M., Ohwada, T., Aoki, J., Kanagawa, M., Toda, T., Nagata, Y., Matsuda, R., Takayama, Y., Tominaga, M. & 1 others, Umeda, M., Dec 1 2018, In : Nature communications. 9, 1, 2049.

Research output: Contribution to journalArticle

flip-flops
Flip flop circuits
Phosphatidylserines
Skeletal Muscle Fibers
Fusion reactions
1 Citation (Scopus)

Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway

Kimura, Y., Tsutsumi, K., Konno, A., Ikegami, K., Hameed, S., Kaneko, T., Kaplan, O. I., Teramoto, T., Fujiwara, M., Ishihara, T., Blacque, O. E. & Setou, M., Dec 1 2018, In : Scientific reports. 8, 1, 8392.

Research output: Contribution to journalArticle

Cilia
p38 Mitogen-Activated Protein Kinases
Tubulin
Starvation
Microtubules
3 Citations (Scopus)

Eukaryotic lipid metabolic pathway is essential for functional chloroplasts and CO2 and light responses in Arabidopsis guard cells

Negi, J., Munemasa, S., Song, B., Tadakuma, R., Fujita, M., Azoulay-Shemer, T., Engineer, C. B., Kusumi, K., Nishida, I., Schroeder, J. I. & Iba, K., Sep 4 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 36, p. 9038-9043 6 p.

Research output: Contribution to journalArticle

Chloroplasts
Metabolic Networks and Pathways
Arabidopsis
Lipids
Light

Involvement of S-type anion channels in disease resistance against an oomycete pathogen in Arabidopsis seedlings

Kurusu, T., Mitsuka, D., Yagi, C., Kitahata, N., Tsutsui, T., Ueda, T., Yamamoto, Y., Negi, J., Iba, K., Betsuyaku, S. & Kuchitsu, K., May 4 2018, In : Communicative and Integrative Biology. 11, 3, p. 1-6 6 p.

Research output: Contribution to journalArticle

Oomycetes
Disease Resistance
Seedlings
Arabidopsis
anions
2 Citations (Scopus)

Morphogenetic mechanism of the acquisition of the dinosaur-type acetabulum

Egawa, S., Saito, D., Abe, G. & Tamura, K., Oct 1 2018, In : Royal Society Open Science. 5, 10, 180604.

Research output: Contribution to journalArticle

Open Access
Dinosaurs
Acetabulum
Hip
Embryonic Structures
Ligands
11 Citations (Scopus)

New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes

Okumoto, K., Ono, T., Toyama, R., Shimomura, A., Nagata, A. & Fujiki, Y., Feb 1 2018, In : Journal of Cell Biology. 217, 2, p. 619-633 15 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Peroxisomes
Microtubules
Insertional Mutagenesis
Amino Acid Sequence
5 Citations (Scopus)

Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes

Imoto, Y., Abe, Y., Honsho, M., Okumoto, K., Ohnuma, M., Kuroiwa, H., Kuroiwa, T. & Fujiki, Y., Dec 1 2018, In : Nature communications. 9, 1, 4634.

Research output: Contribution to journalArticle

Dynamins
Mitochondria
Fueling
Peroxisomes
mitochondria

SPF-CellTracker: Tracking Multiple Cells with Strongly-Correlated Moves Using a Spatial Particle Filter

Hirose, O., Kawaguchi, S., Tokunaga, T., Toyoshima, Y., Teramoto, T., Kuge, S., Ishihara, T., Iino, Y. & Yoshida, R., Nov 1 2018, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 15, 6, p. 1822-1831 10 p., 8186251.

Research output: Contribution to journalArticle

Cell Tracking
Particle Filter
Neurons
Imaging techniques
Cell
8 Citations (Scopus)

Structure-Based Chemical Design of Abscisic Acid Antagonists That Block PYL-PP2C Receptor Interactions

Takeuchi, J., Mimura, N., Okamoto, M., Yajima, S., Sue, M., Akiyama, T., Monda, K., Iba, K., Ohnishi, T. & Todoroki, Y., May 18 2018, In : ACS Chemical Biology. 13, 5, p. 1313-1321 9 p.

Research output: Contribution to journalArticle

Abscisic Acid
Phosphoprotein Phosphatases
Protein Phosphatase 2C
Acid Phosphatase
Tryptophan
6 Citations (Scopus)

α-Catenin Controls the Anisotropy of Force Distribution at Cell-Cell Junctions during Collective Cell Migration

Matsuzawa, K., Himoto, T., Mochizuki, Y. & Ikenouchi, J., Jun 19 2018, In : Cell Reports. 23, 12, p. 3447-3456 10 p.

Research output: Contribution to journalArticle

Catenins
Intercellular Junctions
Anisotropy
Cell Movement
Adherens Junctions
2017
5 Citations (Scopus)

BAK regulates catalase release from peroxisomes

Fujiki, Y., Miyata, N., Mukai, S., Okumoto, K. & Cheng, E. H., Mar 17 2017, In : Molecular & Cellular Oncology . 4, 3, e1306610.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channel 2
Peroxisomes
Catalase
Permeability
Mitochondria
5 Citations (Scopus)

Contribution of the S-type anion channel SLAC1 to stomatal control and its dependence on developmental stage in rice

Kusumi, K., Hashimura, A., Yamamoto, Y., Negi, J. & Iba, K., Jan 1 2017, In : Plant and Cell Physiology. 58, 12, p. 2085-2094 10 p.

Research output: Contribution to journalArticle

anions
Anions
developmental stages
rice
tillering
4 Citations (Scopus)

Defining the dynamin-based ring organizing center on the peroxisome-dividing machinery isolated from Cyanidioschyzon merolae

Imoto, Y., Abe, Y., Okumoto, K., Honsho, M., Kuroiwa, H., Kuroiwa, T. & Fujiki, Y., Jan 1 2017, In : Journal of Cell Science. 130, 5, p. 853-867 15 p.

Research output: Contribution to journalArticle

Dynamins
Peroxisomes
Guanosine Triphosphate
Rhodophyta
Plastids
1 Citation (Scopus)

Differential effects of phosphatidylinositol 4-kinase (PI4K) and 3-kinase (PI3K) inhibitors on stomatal responses to environmental signals

Takahashi, S., Monda, K., Higaki, T., Hashimoto-Sugimoto, M., Negi, J., Hasezawa, S. & Iba, K., May 1 2017, In : Frontiers in Plant Science. 8, 677.

Research output: Contribution to journalArticle

1-phosphatidylinositol 4-kinase
phosphotransferases (kinases)
abscisic acid
H-transporting ATP synthase
phosphatidylinositols
5 Citations (Scopus)

Emphatic visualization of sphingomyelin-rich domains by inter-lipid FRET imaging using fluorescent sphingomyelins

Kinoshita, M., Ano, H., Murata, M., Shigetomi, K., Ikenouchi, J. & Matsumori, N., Dec 1 2017, In : Scientific reports. 7, 1, 16801.

Research output: Contribution to journalArticle

lipids
energy transfer
liquids
partitions
membranes
22 Citations (Scopus)

Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features

Seki, R., Li, C., Fang, Q., Hayashi, S., Egawa, S., Hu, J., Xu, L., Pan, H., Kondo, M., Sato, T., Matsubara, H., Kamiyama, N., Kitajima, K., Saito, D., Liu, Y., Gilbert, M. T. P., Zhou, Q., Xu, X., Shiroishi, T., Irie, N. & 2 others, Tamura, K. & Zhang, G., Feb 6 2017, In : Nature communications. 8, 14229.

Research output: Contribution to journalArticle

Open Access
Feathers
birds
Birds
Histone Code
Extremities
4 Citations (Scopus)

Localization of protein kinase NDR2 to peroxisomes and its role in ciliogenesis

Abe, S., Nagai, T., Masukawa, M., Okumoto, K., Homma, Y., Fujiki, Y. & Mizuno, K., Mar 10 2017, In : Journal of Biological Chemistry. 292, 10, p. 4089-4098 10 p.

Research output: Contribution to journalArticle

Peroxisomes
Protein-Serine-Threonine Kinases
Cell proliferation
Catalase
Protein Kinases
1 Citation (Scopus)

Multiple signaling pathways coordinately regulate forgetting of olfactory adaptation through control of sensory responses in caenorhabditis elegans

Kitazono, T., Hara-Kuge, S., Matsuda, O., Inoue, A., Fujiwara, M. & Ishihara, T., Oct 18 2017, In : Journal of Neuroscience. 37, 42, p. 10240-10251 12 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Caenorhabditis elegans
Sensory Receptor Cells
TYK2 Kinase
Neurons
4 Citations (Scopus)

Regulation of TG accumulation and lipid droplet morphology by the novel TLDP1 in Aurantiochytrium limacinum F26-b

Watanabe, T., Sakiyama, R., Iimi, Y., Sekine, S., Abe, E., Nomura, K. H., Nomura, K., Ishibashi, Y., Okino, N., Hayashi, M. & Ito, M., Jan 1 2017, In : Journal of Lipid Research. 58, 12, p. 2334-2347 14 p.

Research output: Contribution to journalArticle

Triglycerides
Lipids
Proteins
Plant Proteins
Electrophoresis, Gel, Two-Dimensional
21 Citations (Scopus)

The VDAC2-BAK axis regulates peroxisomal membrane permeability

Hosoi, K., Miyata, N., Mukai, S., Furuki, S., Okumoto, K., Cheng, E. H. & Fujiki, Y., Mar 6 2017, In : Journal of Cell Biology. 216, 3, p. 709-722

Research output: Contribution to journalArticle

Peroxisomes
Permeability
Membranes
Peroxisomal Disorders
Inborn Genetic Diseases
5 Citations (Scopus)

Universal glass-forming behavior of in vitro and living cytoplasm

Nishizawa, K., Fujiwara, K., Ikenaga, M., Nakajo, N., Yanagisawa, M. & Mizuno, D., Dec 1 2017, In : Scientific reports. 7, 1, 15143.

Research output: Contribution to journalArticle

cytoplasm
glass
crowding
metabolism
macromolecules
4 Citations (Scopus)

Upstream regulation for initiation of restricted Shh expression in the chick limb bud

Matsubara, H., Saito, D., Abe, G., Yokoyama, H., Suzuki, T. & Tamura, K., May 1 2017, In : Developmental Dynamics. 246, 5, p. 417-430 14 p.

Research output: Contribution to journalArticle

Open Access
Limb Buds
Extremities
Morphogenesis
Gene Expression
Gene Regulatory Networks
2016
7 Citations (Scopus)

Accurate Automatic Detection of Densely Distributed Cell Nuclei in 3D Space

Toyoshima, Y., Tokunaga, T., Hirose, O., Kanamori, M., Teramoto, T., Jang, M. S., Kuge, S., Ishihara, T., Yoshida, R. & Iino, Y., Jun 2016, In : PLoS Computational Biology. 12, 6, e1004970.

Research output: Contribution to journalArticle

automatic detection
cell nucleus
Cell Nucleus
Neurons
Nucleus
17 Citations (Scopus)

A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing

Aoki, K., Maeda, F., Nagasako, T., Mochizuki, Y., Uchida, S. & Ikenouchi, J., Mar 29 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 13, p. E1863-E1871

Research output: Contribution to journalArticle

Blister
Actins
Membranes
Actin Cytoskeleton
Cell Membrane
12 Citations (Scopus)

Chondroitin 4-O-Sulfotransferase is indispensable for sulfation of chondroitin and plays an important role in maintaining normal life span and oxidative stress responses in nematodes

Izumikawa, T., Dejima, K., Watamoto, Y., Nomura, K. H., Kanaki, N., Rikitake, M., Tou, M., Murata, D., Yanagita, E., Kano, A., Mitani, S., Nomura, K. & Kitagawa, H., Oct 28 2016, In : Journal of Biological Chemistry. 291, 44, p. 23294-23304 11 p.

Research output: Contribution to journalArticle

chondroitin 4-sulfotransferase
Chondroitin
Sulfotransferases
Oxidative stress
Chondroitin Sulfates
7 Citations (Scopus)

DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility

Nishimura, T., Ito, S., Saito, H., Hiver, S., Shigetomi, K., Ikenouchi, J. & Takeichi, M., Jan 1 2016, In : Journal of Cell Biology. 215, 4, p. 559-573 15 p.

Research output: Contribution to journalArticle

Membranes
Actins
Actin Cytoskeleton
Epithelial Cells
17 Citations (Scopus)

Dominant and recessive mutations in the Raf-like kinase HT1 gene completely disrupt stomatal responses to CO2 in Arabidopsis

Hashimoto-Sugimoto, M., Negi, J., Monda, K., Higaki, T., Isogai, Y., Nakano, T., Hasezawa, S. & Iba, K., May 28 2016, In : Journal of Experimental Botany. 67, 11, p. 3251-3261 11 p.

Research output: Contribution to journalArticle

raf Kinases
Arabidopsis
phosphotransferases (kinases)
Phosphotransferases
mutation

Effects of near-infrared sorting and fungicide treatment on the germination rate of Cryptomeria japonica and Chamaecyparis obtusa seeds

Hara, M., Matsuda, O., Ochiai, Y., Tobita, H. & Utsugi, H., Jan 1 2016, In : Nihon Ringakkai Shi/Journal of the Japanese Forestry Society. 98, 5, p. 247-251 5 p.

Research output: Contribution to journalArticle

Chamaecyparis obtusa
Cryptomeria japonica
fungicide
sorting
fungicides
18 Citations (Scopus)

Enhanced stomatal conductance by a spontaneous Arabidopsis tetraploid, Me-0, results from increased stomatal size and greater stomatal aperture

Monda, K., Araki, H., Kuhara, S., Ishigaki, G., Akashi, R., Negi, J., Kojima, M., Sakakibara, H., Takahashi, S., Hashimoto-Sugimoto, M., Goto, N. & Iba, K., Mar 1 2016, In : Plant physiology. 170, 3, p. 1435-1444 10 p.

Research output: Contribution to journalArticle

Tetraploidy
Arabidopsis
tetraploidy
stomatal conductance
Ecotype
10 Citations (Scopus)

Gonadal Maturation Changes Chemotaxis Behavior and Neural Processing in the Olfactory Circuit of Caenorhabditis elegans

Fujiwara, M., Aoyama, I., Hino, T., Teramoto, T. & Ishihara, T., Jan 1 2016, In : Current Biology. 26, 12, p. 1522-1531 10 p.

Research output: Contribution to journalArticle

chemotaxis
Caenorhabditis elegans
Chemotaxis
Diacetyl
germ cells
8 Citations (Scopus)
chickens
Hedgehogs
embryos
Mesoderm
Chickens
10 Citations (Scopus)

PAR3-APKC regulates Tiam1 by modulating suppressive internal interactions

Matsuzawa, K., Akita, H., Watanabe, T., Kakeno, M., Matsui, T., Wang, S. & Kaibuchi, K., May 1 2016, In : Molecular biology of the cell. 27, 9, p. 1511-1523 13 p.

Research output: Contribution to journalArticle

Open Access
GTP Phosphohydrolase Activators
Platelet-Derived Growth Factor Receptors
Protein Binding
Catalytic Domain
Protein Domains
2015
21 Citations (Scopus)

A highly accurate inclusive cancer screening test using Caenorhabditis elegans scent detection

Hirotsu, T., Sonoda, H., Uozumi, T., Shinden, Y., Mimori, K., Maehara, Y., Ueda, N. & Hamakawa, M., Mar 11 2015, In : PloS one. 10, 3, e0118699.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Odors
Early Detection of Cancer
Neurons
Screening
7 Citations (Scopus)

Angiogenesis in the developing spinal cord: Blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists

Takahashi, T., Takase, Y., Yoshino, T., Saito, D., Tadokoro, R. & Takahashi, Y., Jan 14 2015, In : PloS one. 10, 1, e0116119.

Research output: Contribution to journalArticle

Blood vessels
angiogenesis
Fetal Blood
blood vessels
spinal cord
6 Citations (Scopus)

A role for Ras in inhibiting circular foraging behavior as revealed by a new method for time and cell-specific RNAi

Hamakawa, M., Uozumi, T., Ueda, N., Iino, Y. & Hirotsu, T., Jan 1 2015, In : BMC Biology. 13, 1 p.

Research output: Contribution to journalArticle

foraging behavior
RNA Interference
RNA interference
RNA
foraging
10 Citations (Scopus)

CaMKII regulates the strength of the epithelial barrier

Shiomi, R., Shigetomi, K., Inai, T., Sakai, M. & Ikenouchi, J., Aug 18 2015, In : Scientific reports. 5, 13262.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Tight Junctions
Epithelial Cells
Up-Regulation
Claudin-1
7 Citations (Scopus)

Determination of seed soundness in conifers cryptomeria japonica and chamaecyparis obtusa using narrow-multiband spectral imaging in the short-wavelength infrared range

Matsuda, O., Hara, M., Tobita, H., Yazaki, K., Nakagawa, T., Shimizu, K., Uemura, A. & Utsugi, H., Jun 17 2015, In : PloS one. 10, 6, e0128358.

Research output: Contribution to journalArticle

Chamaecyparis
Cryptomeria
Coniferophyta
Chamaecyparis obtusa
Cryptomeria japonica
31 Citations (Scopus)

EPLIN is a crucial regulator for extrusion of RasV12- transformed cells

Ohoka, A., Kajita, M., Ikenouchi, J., Yako, Y., Kitamoto, S., Kon, S., Ikegawa, M., Shimada, T., Ishikawa, S. & Fujita, Y., Jan 1 2015, In : Journal of Cell Science. 128, 4, p. 781-789 9 p.

Research output: Contribution to journalArticle

Epithelium
Filamins
Myosin Type II
Myosin-Light-Chain Kinase
Cyclic AMP-Dependent Protein Kinases
20 Citations (Scopus)

Identification of non-Ser/Thr-Pro consensus motifs for Cdk1 and their roles in mitotic regulation of C2H2 zinc finger proteins and Ect2

Suzuki, K., Sako, K., Akiyama, K., Isoda, M., Senoo, C., Nakajo, N. & Sagata, N., Jan 1 2015, In : Scientific reports. 5, 7929.

Research output: Contribution to journalArticle

Proteins
Mitosis
Cyclin B
Peptide Library
Nuclear Localization Signals
12 Citations (Scopus)

Metabotropic glutamate receptors: Modulators of context-dependent feeding behaviour in C. elegans

Dillon, J., Franks, C. J., Murray, C., Edwards, R. J., Calahorro, F., Ishihara, T., Katsura, I., Holden-Dye, L. & O'Connor, V., Jun 12 2015, In : Journal of Biological Chemistry. 290, 24, p. 15052-15065 14 p.

Research output: Contribution to journalArticle

Pharyngeal Muscles
Metabotropic Glutamate Receptors
Feeding Behavior
Modulators
Optogenetics
16 Citations (Scopus)

Natural variation in stomatal responses to environmental changes among Arabidopsis thaliana ecotypes

Takahashi, S., Monda, K., Negi, J., Konishi, F., Ishikawa, S., Hashimoto-Sugimoto, M., Goto, N. & Iba, K., Feb 23 2015, In : PloS one. 10, 2, e0117449.

Research output: Contribution to journalArticle

Ecotype
ecotypes
Arabidopsis
Atmospheric humidity
Arabidopsis thaliana