Research Output 1979 2020

2 Citations (Scopus)

A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-oforigin effects

Amakawa, Y., Sakata, Y., Hoki, Y., Arata, S., Shioda, S., Fukagawa, T., Sasaki, H. & Sado, T., Dec 15 2015, In : Development (Cambridge). 142, 24, p. 4299-4308 10 p.

Research output: Contribution to journalArticle

Alleles
Mothers
X Chromosome Inactivation
Blastocyst
X-Linked Genes
445 Citations (Scopus)

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. I. & Nakayama, K., May 4 1999, In : EMBO Journal. 18, 9, p. 2401-2410 10 p.

Research output: Contribution to journalArticle

F-Box Proteins
Proteolysis
Catenins
Ubiquitin
Ubiquitination
6 Citations (Scopus)

Angiotensin I-converting enzyme gene polymorphism modifies the smoking-cancer association: The Hisayama Study

Arima, H., Kiyohara, Y., Tanizaki, Y., Nakabeppu, Y., Kubo, M., Kato, I., Sueishi, K., Tsuneyoshi, M., Fujishima, M. & Iida, M., Jun 1 2006, In : European Journal of Cancer Prevention. 15, 3, p. 196-201 6 p.

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Smoking
Genotype
Genes
Neoplasms
19 Citations (Scopus)

An important role of Tyk2 in APC function of dendritic cells for priming CD8+ T cells producing IFN-γ

Aizu, K., Li, W., Yajima, T., Arai, T., Shimoda, K., Nimura, Y. & Yoshikai, Y., Nov 1 2006, In : European Journal of Immunology. 36, 11, p. 3060-3070 11 p.

Research output: Contribution to journalArticle

TYK2 Kinase
Dendritic Cells
Listeria monocytogenes
T-Lymphocytes
Adoptive Transfer
12 Citations (Scopus)

An improved method to make sequential deletion mutants for DNA sequencing.

Nakayama, K. & Nakauchi, H., Oct 1989, In : Trends in genetics : TIG. 5, 10, 1 p.

Research output: Contribution to journalArticle

Chromosome Deletion
DNA Sequence Analysis
Mutation
6 Citations (Scopus)

An improved restriction enzyme accessibility assay for analyzing changes in chromatin structure in samples of limited cell number

Ohkawa, Y., Mallappa, C., Vallaster, C. S. D. & Imbalzano, A. N., Jan 2 2012, Myogenesis: Methods and Protocols. DiMario, J. (ed.). p. 531-542 12 p. (Methods in Molecular Biology; vol. 798).

Research output: Chapter in Book/Report/Conference proceedingChapter

Enzyme Assays
Chromatin
Cell Count
Biomedical Technology Assessment
Cues
23 Citations (Scopus)

An improved scoring scheme for predicting glycan structures from gene expression data.

Suga, A., Yamanishi, Y., Hashimoto, K., Goto, S. & Kanehisa, M., Jan 1 2007, In : Genome informatics. International Conference on Genome Informatics. 18, p. 237-246 10 p.

Research output: Contribution to journalArticle

Polysaccharides
Gene Expression
Glycosyltransferases
Computational Biology
Precursor Cell Lymphoblastic Leukemia-Lymphoma
15 Citations (Scopus)

An increase in number of T-cell receptor γ/δ-bearing T cells in athymic nude mice treated with complete Freund's adjuvants

Yoshikai, Y., Matsuzaki, G., Inoue, T. & Nomoto, K., Jan 1 1990, In : Immunology. 70, 1, p. 61-65 5 p.

Research output: Contribution to journalArticle

Freund's Adjuvant
T-Cell Antigen Receptor
Nude Mice
T-Lymphocytes
Groin
Open Access
Psoriasis
Genome-Wide Association Study
Lipid Metabolism
Skin
Transcription Factor AP-1
2 Citations (Scopus)

An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma

Sakurada, A., Miyanishi, K., Tanaka, S., Sato, M., Sakamoto, H., Kawano, Y., Takada, K., Nakabeppu, Y., Kobune, M. & Kato, J., Dec 1 2018, In : Free Radical Biology and Medicine. 129, p. 88-96 9 p.

Research output: Contribution to journalArticle

Polymorphism
Single Nucleotide Polymorphism
Hepatocellular Carcinoma
Nucleotides
Genes
64 Citations (Scopus)

An isoleucine zipper peptide forms a native-like triple stranded coiled coil in solution

Suzuki, K., Hiroaki, H., Kohda, D. & Tanaka, T., Nov 1 1998, In : Protein Engineering. 11, 11, p. 1051-1055 5 p.

Research output: Contribution to journalArticle

Isoleucine
Fasteners
Peptides
Amides
Protons
18 Citations (Scopus)
Flavonoids
Methylation
Liquid chromatography
Liquid Chromatography
Isotopes
37 Citations (Scopus)

An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating il-1 production in dendritic cells

Yasukawa, S., Miyazaki, Y., Yoshii, C., Nakaya, M., Ozaki, N., Toda, S., Kuroda, E., Ishibashi, K. I., Yasuda, T., Natsuaki, Y., Mi-Ichi, F., Iizasa, E., Nakahara, T., Yamazaki, M., Kabashima, K., Iwakura, Y., Takai, T., Saito, T., Kurosaki, T., Malissen, B. & 4 others, Ohno, N., Furue, M., Yoshida, H. & Hara, H., May 7 2014, In : Nature communications. 5, 3755.

Research output: Contribution to journalArticle

spleen
Haptens
tyrosine
Contact Dermatitis
interleukins
66 Citations (Scopus)

Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

Floc'h, A. L., Tanaka, Y., Bantilan, N. S., Voisinne, G., Altan-Bonnet, G., Fukui, Y. & Huse, M., Nov 2013, In : Journal of Experimental Medicine. 210, 12, p. 2721-2737 17 p.

Research output: Contribution to journalArticle

Immunological Synapses
Actins
T-Lymphocytes
Synaptic Membranes
rho GTP-Binding Proteins
26 Citations (Scopus)

An optogenetic system for interrogating the temporal dynamics of Akt

Katsura, Y., Kubota, H., Kunida, K., Kanno, A., Kuroda, S. & Ozawa, T., Oct 1 2015, In : Scientific reports. 5, 14589.

Research output: Contribution to journalArticle

Optogenetics
Light
Muscular Atrophy
Protein-Serine-Threonine Kinases
Lighting
10 Citations (Scopus)

A novel, polymer-coated oncolytic measles virus overcomes immune suppression and induces robust antitumor activity

Nosaki, K., Hamada, K., Takashima, Y., Sagara, M., Matsumura, Y., Miyamoto, S., Hijikata, Y., Okazaki, T., Nakanishi, Y. & Tani, K., Nov 2 2016, In : Molecular Therapy - Oncolytics. 3, 1 p., 16022.

Research output: Contribution to journalArticle

Oncolytic Viruses
Measles virus
Polymers
Viruses
Oncolytic Virotherapy
3 Citations (Scopus)

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Fujii, T., Yamasaki, R., Iinuma, K., Tsuchimoto, D., Hayashi, Y., Saitoh, B. Y., Matsushita, T., Kido, M. A., Aishima, S., Nakanishi, H., Nakabeppu, Y. & Kira, J. I., Aug 2018, In : Annals of Neurology. 84, 2, p. 208-224 17 p.

Research output: Contribution to journalArticle

Neuralgia
Autoantibodies
Spinal Ganglia
Neurons
Unmyelinated Nerve Fibers
40 Citations (Scopus)

A novel autoregulatory mechanism for transcriptional activation of the IL-15 gene by a nonsecretable isoform of IL-15 generated by alternative splicing

Nishimura, H., Fujimoto, A., Tamura, N., Yajima, T., Wajjwalku, W. & Yoshikai, Y., Jan 1 2005, In : FASEB Journal. 19, 1, p. 19-28 10 p.

Research output: Contribution to journalArticle

Interleukin-15
alternative splicing
Alternative Splicing
transcriptional activation
Transcriptional Activation
44 Citations (Scopus)

A novel CD3 J11d+ subset of CD4+CD8 cells repopulating thymus in radiation bone marrow chimeras

Matsumoto, K., Yoshikai, Y., Matsuzaki, G., Asano, T. & Nomoto, K., Jul 1989, In : European Journal of Immunology. 19, 7, p. 1203-1207 5 p.

Research output: Contribution to journalArticle

Thymus Gland
Bone Marrow
Radiation
Thymocytes
Bone Marrow Transplantation
6 Citations (Scopus)

A novel exogenous mammary tumor virus encoding MHC class II H2E-independent superantigen specific foor Tcr-Vβ14

Wajjwalku, W., Ando, Y., Niimi, N. & Yoshikai, Y., Jan 1 1995, In : Immunogenetics. 41, 2-3, p. 156-158 3 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Inbred BALB C Mouse
CD4-Positive T-Lymphocytes
Antigen Receptors, T-Cell, alpha-beta
Mouse mammary tumor virus
2 Citations (Scopus)

A novel frameshift mutation of DDHD1 in a Japanese patient with autosomal recessive spastic paraplegia

Miura, S., Morikawa, T., Fujioka, R., Kosaka, K., Yamada, K., Hattori, G., Motomura, M., Taniwaki, T. & Shibata, H., Aug 1 2016, In : European Journal of Medical Genetics. 59, 8, p. 413-416 4 p.

Research output: Contribution to journalArticle

Frameshift Mutation
Mutation
Paraplegia
Genes
Lower Extremity
20 Citations (Scopus)

A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis

Unoki, M., Kumamoto, K., Robles, A. I., Shen, J. C., Zheng, Z. M. & Harris, C. C., Nov 26 2008, In : FEBS Letters. 582, 28, p. 3868-3874 7 p.

Research output: Contribution to journalArticle

Cell growth
Cell Cycle Checkpoints
Protein Isoforms
Cells
Apoptosis
3 Citations (Scopus)

A novel missense mutation of RYR1 in familial idiopathic hyper CK-emia

Sano, K., Miura, S., Fujiwara, T., Fujioka, R., Yorita, A., Noda, K., Kida, H., Azuma, K., Kaieda, S., Yamamoto, K., Taniwaki, T., Fukumaki, Y. & Shibata, H., Sep 15 2015, In : Journal of the Neurological Sciences. 356, 1-2, p. 142-147 6 p., 13864.

Research output: Contribution to journalArticle

Missense Mutation
Creatine Kinase
Pedigree
Nucleotides
Genes
3 Citations (Scopus)

A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy

Miura, S., Morikawa, T., Fujioka, R., Noda, K., Kosaka, K., Taniwaki, T. & Shibata, H., Sep 2017, In : European Journal of Medical Genetics. 60, 9, p. 474-478 5 p.

Research output: Contribution to journalArticle

Guanine Nucleotides
Protein Subunits
Carrier Proteins
Exome
Lower Extremity
63 Citations (Scopus)

A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines

Matsuguchi, T., Musikacharoen, T., Johnson, T. R., Kraft, A. S. & Yoshikai, Y., Oct 10 2001, In : Molecular and cellular biology. 21, 20, p. 6999-7009 11 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Phosphatases
JNK Mitogen-Activated Protein Kinases
Lipopolysaccharides
Macrophages
Cell Line
24 Citations (Scopus)

A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae

Nunoshiba, T., Ishida, R., Sasaki, M., Iwai, S., Nakabeppu, Y. & Yamamoto, K., Dec 6 2004, In : Nucleic acids research. 32, 18, p. 5339-5348 10 p.

Research output: Contribution to journalArticle

Purine Nucleosides
Saccharomyces cerevisiae
Escherichia coli
Genes
Nucleotides
34 Citations (Scopus)

A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells

Nishimura, H., Yajima, T., Muta, H., Podack, E. R., Tani, K. & Yoshikai, Y., Oct 1 2005, In : Journal of Immunology. 175, 7, p. 4627-4634 8 p.

Research output: Contribution to journalArticle

CD30 Ligand
T-Lymphocytes
Listeriosis
Listeria monocytogenes
Spleen
36 Citations (Scopus)

A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection

Tang, C., Yamada, H., Shibata, K., Muta, H., Wajjwalku, W., Podack, E. R. & Yoshikai, Y., Nov 1 2008, In : Journal of Immunology. 181, 9, p. 6316-6327 12 p.

Research output: Contribution to journalArticle

Cell Communication
T-Lymphocytes
Infection
Bacillus
Th1 Cells
36 Citations (Scopus)

A novel role of IL-15 in early activation of memory CD8+ CTL after reinfection

Yajima, T., Nishimura, H., Sad, S., Shen, H., Kuwano, H. & Yoshikai, Y., Mar 15 2005, In : Journal of Immunology. 174, 6, p. 3590-3597 8 p.

Research output: Contribution to journalArticle

Interleukin-15
T-Lymphocytes
Knockout Mice
Transgenic Mice
Granzymes
110 Citations (Scopus)

A novel route for connexin 43 to inhibit cell proliferation: Negative regulation of S-phase kinase-associated protein (Skp 2)

Zhang, Y. W., Nakayama, K., Nakayama, K. & Morita, I., Apr 1 2003, In : Cancer Research. 63, 7, p. 1623-1630 8 p.

Research output: Contribution to journalArticle

S-Phase Kinase-Associated Proteins
Connexin 43
Cell Proliferation
Embryonic Structures
Fibroblasts
100 Citations (Scopus)

Anovel serum metabolomics-based diagnostic approach to pancreatic cancer

Kobayashi, T., Nishiumi, S., Ikeda, A., Yoshie, T., Sakai, A., Matsubara, A., Izumi, Y., Tsumura, H., Tsuda, M., Nishisaki, H., Hayashi, N., Kawano, S., Fujiwara, Y., Minami, H., Takenawa, T., Azuma, T. & Yoshida, M., Apr 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 4, p. 571-579 9 p.

Research output: Contribution to journalArticle

Metabolomics
Pancreatic Neoplasms
Chronic Pancreatitis
Serum
Healthy Volunteers
10 Citations (Scopus)

A novel Vβ 2-specific endogenous mouse mammary tumor virus which is capable of producing a milk-borne exogenous virus

Niimi, N., Wajjwalku, W., Ando, Y., Nakamura, N., Ueda, M. & Yoshikai, Y., Nov 1 1995, In : Journal of virology. 69, 11, p. 7269-7273 5 p.

Research output: Contribution to journalArticle

Mouse mammary tumor virus
superantigens
Superantigens
Milk
T-lymphocytes
104 Citations (Scopus)

An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress

Yoshimura, D., Sakumi, K., Ohno, M., Sakai, Y., Furuichi, M., Iwai, S. & Nakabeppu, Y., Sep 26 2003, In : Journal of Biological Chemistry. 278, 39, p. 37965-37973 9 p.

Research output: Contribution to journalArticle

Nucleoside-Triphosphatase
Purine Nucleosides
Oxidative stress
Cell death
Oxidative Stress
15 Citations (Scopus)

Antagonistic regulation of cell-matrix adhesion by FosB and ΔFosB/Δ2ΔFosB encoded by alternatively spliced forms of fosB transcripts

Ohnishi, Y. N., Sakumi, K., Yamazaki, K., Ohnishi, Y. H., Miura, T., Tominaga, Y. & Nakabeppu, Y., Nov 1 2008, In : Molecular biology of the cell. 19, 11, p. 4717-4729 13 p.

Research output: Contribution to journalArticle

Cell-Matrix Junctions
Null Lymphocytes
Alleles
Embryonic Stem Cells
Genes
9 Citations (Scopus)

Antibacterial effect of bovine milk antibody against Escherichia coli in a mouse indigenous infection model

Nomoto, K., Matsuoka, Y., Hayakawa, K., Ohwaki, M., Kan, T., Yoshikai, Y. & Nomoto, K., May 1 1992, In : Medical Microbiology and Immunology. 181, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Milk
Escherichia coli
Antibodies
Infection
Fluorouracil
56 Citations (Scopus)

Antibodies against leukocyte function-associated antigen-1 and against intercellular adhesion molecule-1 together suppress the progression of experimental allergic encephalomyelitis

Kobayashi, Y., Kawai, K., Honda, H., Tomida, S., Niimi, N., Tamatani, T., Miyasaka, M. & Yoshikai, Y., Sep 1995, In : Cellular Immunology. 164, 2, p. 295-305 11 p.

Research output: Contribution to journalArticle

Lymphocyte Function-Associated Antigen-1
Autoimmune Experimental Encephalomyelitis
Intercellular Adhesion Molecule-1
Antibodies
Multiple Sclerosis

Antibody-mediated T-cell reduction or increased levels of chimerism overcome resistance to cyclophosphamide-induced tolerance in NKT-deficient mice

Onzuka, T., Tomita, Y., Okano, S., Shimizu, I., Yamada, H., Yoshikai, Y. & Tominaga, R., Aug 1 2010, In : Scandinavian Journal of Immunology. 72, 2, p. 106-117 12 p.

Research output: Contribution to journalArticle

Chimerism
Natural Killer T-Cells
Cyclophosphamide
T-Lymphocytes
Antibodies
5 Citations (Scopus)

Antigen availability and DOCK2-driven motility govern CD4+ t cell interactions with dendritic cells in vivo

Ackerknecht, M., Gollmer, K., Germann, P., Ficht, X., Abe, J., Fukui, Y., Swoger, J., Ripoll, J., Sharpe, J. & Stein, J. V., Jul 15 2017, In : Journal of Immunology. 199, 2, p. 520-530 11 p.

Research output: Contribution to journalArticle

Cell Communication
Dendritic Cells
Antigens
T-Lymphocytes
Peptides
71 Citations (Scopus)

Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation

Mukaino, M., Nakamura, M., Yamada, O., Okada, S., Morikawa, S., Renault-Mihara, F., Iwanami, A., Ikegami, T., Ohsugi, Y., Tsuji, O., Katoh, H., Matsuzaki, Y., Toyama, Y., Liu, M. & Okano, H., Aug 1 2010, In : Experimental Neurology. 224, 2, p. 403-414 12 p.

Research output: Contribution to journalArticle

Interleukin-6 Receptors
Microglia
Spinal Cord Injuries
Inflammation
Antibodies
9 Citations (Scopus)

Antithrombin III injection via the portal vein suppresses liver damage

Miyazaki, M., Kato, M., Tanaka, M., Tanaka, K., Takao, S., Kohjima, M., Ito, T., Enjoji, M., Nakamuta, M., Kotoh, K. & Takayanagi, R., Apr 28 2012, In : World Journal of Gastroenterology. 18, 16, p. 1884-1891 8 p.

Research output: Contribution to journalArticle

Antithrombin III
Portal Vein
Injections
Liver
Galactosamine
5 Citations (Scopus)

Antitumor activity of recombinant Bacille Calmette-Guérin secreting interleukin-15-Ag85B fusion protein against bladder cancer

Takeuchi, A., Eto, M., Tatsugami, K., Shiota, M., Yamada, H., Kamiryo, Y., Dejima, T., Kashiwagi, E., Kiyoshima, K., Inokuchi, J., Takahashi, R., Yokomizo, A., Ohara, N. & Yoshikai, Y., Jun 2016, In : International Immunopharmacology. 35, p. 327-331 5 p.

Research output: Contribution to journalArticle

Interleukin-15
Urinary Bladder Neoplasms
Bacillus
Proteins
Urinary Bladder
60 Citations (Scopus)

Antitumor effect of heat-killed Lactobacillus plantarum L-137 through restoration of impaired interleukin-12 production in tumor-bearing mice

Murosaki, S., Muroyama, K., Yamamoto, Y. & Yoshikai, Y., Jan 1 2000, In : Cancer Immunology Immunotherapy. 49, 3, p. 157-164 8 p.

Research output: Contribution to journalArticle

1-phenyl-6,7-dihydroxy-isochroman
Lactobacillus plantarum
Interleukin-12
Hot Temperature
Injections
2 Citations (Scopus)

Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

Araki, M., Kurihara, M., Kinoshita, S., Awane, R., Sato, T., Ohkawa, Y. & Inoue, Y. H., Jan 1 2019, In : DMM Disease Models and Mechanisms. 12, 6, dmm037721.

Research output: Contribution to journalArticle

Open Access
Immune system
Drosophila
Tumors
Immune System
Peptides
6 Citations (Scopus)

An unique CD4+CD8+ intestinal intraepithelial lymphocyte specific for DnaK (Escherichia coli HSP70) may be selected by intestinal microflora of rats

Kimura, Y., Sakai, T., Takeuchi, M., Matsumoto, Y., Watanabe, K., Yuuki, M., Takada, T. & Yoshikai, Y., Mar 1 1997, In : Immunobiology. 196, 5, p. 550-566 17 p.

Research output: Contribution to journalArticle

Lymphocytes
Escherichia coli
Diet
Gastrointestinal Microbiome
Gastrointestinal Contents
8 Citations (Scopus)

A one-step immunostaining method to visualize rodent muscle fiber type within a single specimen

Sawano, S., Komiya, Y., Ichitsubo, R., Ohkawa, Y., Nakamura, M., Tatsumi, R., Ikeuchi, Y. & Mizunoya, W., Nov 2016, In : PloS one. 11, 11, 0166080.

Research output: Contribution to journalArticle

muscle fibers
Muscle
Rodentia
rodents
Muscles
1 Citation (Scopus)

A panel of specific monoclonal antibodies directed against various phosphorylated histones H3

Yoshimi, T., Ohkawa, Y., Azuma, M. & Tachibana, T., Apr 1 2013, In : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 32, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

Histones
Monoclonal Antibodies
Epigenomics
Histone Code
Phosphorylation
108 Citations (Scopus)

APE1- And APE2-dependent DNA breaks in immunoglobulin class switch recombination

Guikema, J. E. J., Linehan, E. K., Tsuchimoto, D., Nakabeppu, Y., Strauss, P. R., Stavnezer, J. & Schrader, C. E., Nov 26 2007, In : Journal of Experimental Medicine. 204, 12, p. 3017-3026 10 p.

Research output: Contribution to journalArticle

DNA Breaks
Immunoglobulin Isotypes
Genetic Recombination
Uracil-DNA Glycosidase
DNA-(Apurinic or Apyrimidinic Site) Lyase

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (Journal of Experimental Medicine (November 26, 2007) 204: 12 (3017-3026))

Guikema, J. E. J., Linehan, E. K., Tsuchimoto, D., Nakabeppu, Y., Strauss, P. R., Stavnezer, J. & Schrader, C. E., Dec 24 2007, In : Journal of Experimental Medicine. 204, 13, 1 p.

Research output: Contribution to journalComment/debate

DNA Breaks
Immunoglobulin Isotypes
Genetic Recombination
Biomedical Research
25 Citations (Scopus)

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes

Sabouri, Z., Okazaki, I. M., Shinkura, R., Begum, N., Nagaoka, H., Tsuchimoto, D., Nakabeppu, Y. & Honjo, T., Oct 2 2009, In : International Immunology. 21, 8, p. 947-955 9 p.

Research output: Contribution to journalArticle

Immunoglobulin Genes
Genetic Recombination
DNA Cleavage
DNA-(Apurinic or Apyrimidinic Site) Lyase
Exonucleases
112 Citations (Scopus)

Aplidin™ induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C δ

García-Fernández, L. F., Losada, A., Alcaide, V., Álvarez, A. M., Cuadrado, A., González, L., Nakayama, K., Nakayama, K., Fernández-Sousa, J. M., Muñoz, A. & Sánchez-Puelles, J. M., Jan 1 2002, In : Oncogene. 21, 49, p. 7533-7544 12 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Protein Kinase C
Protein Kinase C-delta
Oxidative Stress
Caspases