Research Output

Article

Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis

Oyamada, A., Ikebe, H., Itsumi, M., Saiwai, H., Okada, S., Shimoda, K., Iwakura, Y., Nakayama, K. I., Iwamoto, Y., Yoshikai, Y. & Yamada, H., Dec 1 2009, In : Journal of Immunology. 183, 11, p. 7539-7546 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2

Inoue, M., Hada, K., Shiraishi, H., Yatsuka, H., Fujinami, H., Morisaki, I., Nishida, Y., Matsubara, E., Ishitani, T., Hanada, R., Matsumoto, M., Penninger, J. M., Ihara, K. & Hanada, T., Jan 1 2020, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53

Wu, H., Pomeroy, S. L., Ferreira, M., Teider, N., Mariani, J., Nakayama, K. I., Hatakeyama, S., Tron, V. A., Saltibus, L. F., Spyracopoulos, L. & Leng, R. P., Mar 1 2011, In : Nature medicine. 17, 3, p. 347-355 9 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1

Hatakeyama, S., Kitagawa, M., Nakayama, K., Shirane, M., Matsumoto, M., Hattori, K., Higashi, H., Nakano, H., Okumura, K., Onoé, K., Good, R. A. & Nakayama, K. I., Mar 30 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 3859-3863 5 p.

Research output: Contribution to journalArticle

168 Citations (Scopus)

Ubiquitin-dependent proteolysis by SCF complex

Nakayama, K. & Nakayama, K. I., Dec 1 2000, In : Seikagaku. 72, 2, p. 113-117 5 p.

Research output: Contribution to journalArticle

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2

Okumura, F., Joo-Okumura, A., Obara, K., Petersen, A., Nishikimi, A., Fukui, Y., Nakatsukasa, K. & Kamura, T., Nov 15 2017, In : Molecular biology of the cell. 28, 24, p. 3532-3541 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase

Yogosawa, S., Hatakeyama, S., Nakayama, K., Miyoshi, H., Kohsaka, S. & Akazawa, C., Dec 16 2005, In : Journal of Biological Chemistry. 280, 50, p. 41619-41627 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle

Jiang, H., Chang, F. C., Ross, A. E., Lee, J., Nakayama, K., Nakayama, K. & Desiderio, S., Jun 10 2005, In : Molecular Cell. 18, 6, p. 699-709 11 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

Hatakeyama, S., Matsumoto, M., Kamura, T., Murayama, M., Chui, D. H., Planel, E., Takahashi, R., Nakayama, K. I. & Takashima, A., Oct 1 2004, In : Journal of Neurochemistry. 91, 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

U Box Proteins as a New Family of Ubiquitin-Protein Ligases

Hatakeyama, S., Yada, M., Matsumoto, M., Ishida, N. & Nakayama, K. I., Aug 31 2001, In : Journal of Biological Chemistry. 276, 35, p. 33111-33120 10 p.

Research output: Contribution to journalArticle

428 Citations (Scopus)

UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer

Kofunato, Y., Kumamoto, K., Saitou, K., Hayase, S., Okayama, H., Miyamoto, K., Sato, Y., Katakura, K., Nakamura, I., Ohki, S., Koyama, Y., Unoki, M. & Takenoshita, S., Dec 1 2012, In : Oncology reports. 28, 6, p. 1997-2002 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

UHRF1 is a novel diagnostic marker of lung cancer

Unoki, M., Daigo, Y., Koinuma, J., Tsuchiya, E., Hamamoto, R. & Nakamura, Y., Jul 13 2010, In : British journal of cancer. 103, 2, p. 217-222 6 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Unique structure (construction and configuration) and evolution of the array of small serum protein genes of Protobothrops flavoviridis snake

Hattori, S., Oda-Ueda, N., Ohno, M., Chijiwa, T., Inamaru, K., Takeuchi, A., Maeda, M., Yamaguchi, K. & Shibata, H., Jul 5 2019, In : Bioscience reports. 39, 7, BSR20190560.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Unusually high conservation of untranslated sequences in cDNAs for Trimeresurus flavoviridis phospholipase A2 isozymes

Ogawa, T., Oda, N., Nakashima, K. I., Sasaki, H., Hattori, M., Sakaki, Y., Kihara, H. & Ohno, M., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 18, p. 8557-8561 5 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis

Gao, Y., Kitagawa, K., Hiramatsu, Y., Kikuchi, H., Isobe, T., Shimada, M., Uchida, C., Hattori, T., Oda, T., Nakayama, K., Nakayama, K. I., Tanaka, T., Konno, H. & Kitagawa, M., Dec 15 2006, In : Cancer Research. 66, 24, p. 11623-11631 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Use of on-line supercritical fluid extraction-supercritical fluid chromatography/tandem mass spectrometry to analyze disease biomarkers in dried serum spots compared with serum analysis using liquid chromatography/tandem mass spectrometry

Suzuki, M., Nishiumi, S., Kobayashi, T., Sakai, A., Iwata, Y., Uchikata, T., Izumi, Y., Azuma, T., Bamba, T. & Yoshida, M., May 30 2017, In : Rapid Communications in Mass Spectrometry. 31, 10, p. 886-894 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

UV damage-induced phosphorylation of HBO1 triggers CRL4DDB2-mediated degradation to regulate cell proliferation

Matsunuma, R., Niida, H., Ohhata, T., Kitagawa, K., Sakai, S., Uchida, C., Shiotani, B., Matsumoto, M., Nakayama, K. I., Ogura, H., Shiiya, N. & Kitagawa, M., Jan 1 2016, In : Molecular and cellular biology. 36, 3, p. 394-406 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R. C., Conaway, J. W. & Nakayama, K. I., Dec 15 2004, In : Genes and Development. 18, 24, p. 3055-3065 11 p.

Research output: Contribution to journalArticle

316 Citations (Scopus)

Visualization and evaluation of the promoter activities of genes for stress-inducible proteins in response to environmental pollutants

Ohashi, T., Satoh, T., Kuwata, M., Fujimura, T. & Taketani, S., Apr 1 2007, In : Yakugaku Zasshi. 127, 4, p. 757-764 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Visualization and exploration of Tcf/Lef function using a highly responsive Wnt/Β-catenin signaling-reporter transgenic zebrafish

Shimizu, N., Kawakami, K. & Ishitani, T., Oct 1 2012, In : Developmental Biology. 370, 1, p. 71-85 15 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Visualization of intrinsically disordered regions of proteins by high-speed atomic force microscopy

Miyagi, A., Tsunaka, Y., Uchihashi, T., Mayanagi, K., Hirose, S., Morikawa, K. & Ando, T., Sep 15 2008, In : ChemPhysChem. 9, 13, p. 1859-1866 8 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Vγl+ γδ T cells play protective roles at an early phase of murine cytomegalovirus infection through production of interferon-γ

Ninomiya, T., Takimoto, H., Matsuzaki, G., Hamano, S., Yoshida, H., Yoshikai, Y., Kimura, G. & Nomoto, K., Jan 1 2000, In : Immunology. 99, 2, p. 187-194 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Vδ1+ T cells are crucial for repertoire formation of γδ T cells in the lung

Li, S., Kishihara, K., Akashi, N., Hara, H., Yoshikai, Y., Maekawa, Y. & Yasutomo, K., Jan 11 2008, In : Biochemical and Biophysical Research Communications. 365, 2, p. 246-251 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Vδ1+ γδ T cells producing CC chemokines may bridge a gap between neutrophils and macrophages in innate immunity during Escherichia coli infection in mice

Yoshikai, Y., Tagawa, T., Shibata, K., Yajima, T., Hara, H. & Kishihara, K., Nov 1 2005, In : International Congress Series. 1285, p. 155-159 5 p.

Research output: Contribution to journalArticle

Vδ1 + γδ T cells producing CC chemokines may bridge a gap between neutrophils and macrophages in innate immunity during Escherichia coli infection in mice

Tagawa, T., Nishimura, H., Yajima, T., Hara, H., Kishihara, K., Matsuzaki, G., Yoshino, I., Maehara, Y. & Yoshikai, Y., Oct 15 2004, In : Journal of Immunology. 173, 8, p. 5156-5164 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Vδ5+ T cells of BALB/c mice recognize the murine heat shock protein 60 target cell specificity

Kobayashi, N., Matsuzaki, G., Yoshikai, Y., Seki, R., Ivanyi, J. & Nomoto, K., Jan 1 1994, In : Immunology. 81, 2, p. 240-246 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

What determines the specificity and outcomes of Ubiquitin signaling?

Ikeda, F., Crosetto, N. & Dikic, I., Nov 24 2010, In : Cell. 143, 5, p. 677-681 5 p.

Research output: Contribution to journalArticle

Open Access
107 Citations (Scopus)

Whole-mount MeFISH: A novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression

Shiura, H., Okamoto, A., Sasaki, H. & Abe, K., Apr 22 2014, In : PloS one. 9, 4, e95750.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Widely-targeted quantitative lipidomics method by supercritical fluid chromatography triple quadrupole mass spectrometry

Takeda, H., Izumi, Y., Takahashi, M., Paxton, T., Tamura, S., Koike, T., Yu, Y., Kato, N., Nagase, K., Shiomi, M. & Bamba, T., Jan 1 2018, In : Journal of Lipid Research. 59, 7, p. 1283-1293 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2 Citations (Scopus)

Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation

Ishiuchi, T. & Takeichi, M., Jul 1 2011, In : Nature Cell Biology. 13, 7, p. 860-866 7 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development

Cho, S. J., Cha, B. S., Kwon, O. S., Lim, J., Shin, D. M., Han, D. W., Ishitani, T., Jho, E. H., Fornace, A. J. & Cha, H. J., Apr 1 2017, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 4, p. 1013-1022 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Wnt/Dkk negative feedback regulates sensory organ size in zebrafish

Wada, H., Ghysen, A., Asakawa, K., Abe, G., Ishitani, T. & Kawakami, K., Aug 19 2013, In : Current Biology. 23, 16, p. 1559-1565 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Wnt-1 signal induces, phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

Kanei-Ishii, C., Ninomiya-Tsuji, J., Tanikawa, J., Nomura, T., Ishitani, T., Kishida, S., Kokura, K., Kurahashi, T., Ichikawa-Iwata, E., Kim, Y., Matsumoto, K. & Ishii, S., Apr 1 2004, In : Genes and Development. 18, 7, p. 816-829 14 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

Wnt signaling regulates left-right axis formation in the node of mouse embryos

Kitajima, K., Oki, S., Ohkawa, Y., Sumi, T. & Meno, C., Aug 15 2013, In : Developmental Biology. 380, 2, p. 222-232 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

XRCC1 interactions with multiple DNA glycosylases: A model for its recruitment to base excision repair

Campalans, A., Marsin, S., Nakabeppu, Y., O'Connor, T. R., Boiteux, S. & Radicella, J. P., Jul 12 2005, In : DNA Repair. 4, 7, p. 826-835 10 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Zebrafish Dmrta2 regulates neurogenesis in the telencephalon

Yoshizawa, A., Nakahara, Y., Izawa, T., Ishitani, T., Tsutsumi, M., Kuroiwa, A., Itoh, M. & Kikuchi, Y., Nov 1 2011, In : Genes to Cells. 16, 11, p. 1097-1109 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Zfp281 Shapes the Transcriptome of Trophoblast Stem Cells and Is Essential for Placental Development

Ishiuchi, T., Ohishi, H., Sato, T., Kamimura, S., Yorino, M., Abe, S., Suzuki, A., Wakayama, T., Suyama, M. & Sasaki, H., May 7 2019, In : Cell Reports. 27, 6, p. 1742-1754.e6

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway

Adachi, S., Homoto, M., Tanaka, R., Hioki, Y., Murakami, H., Suga, H., Matsumoto, M., Nakayama, K. I., Hatta, T., Iemura, S. I. & Natsume, T., Jan 1 2014, In : Nucleic acids research. 42, 15, p. 10037-10049 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

Muratsu, D., Yoshiga, D., Taketomi, T., Onimura, T., Seki, Y., Matsumoto, A. & Nakamura, S., Jul 9 2013, In : PloS one. 8, 7, e67906.

Research output: Contribution to journalArticle

26 Citations (Scopus)

ΔFosB, but not FosB, induces delayed apoptosis independent of cell proliferation in the Rat1a embryo cell line

Tahara, K., Tsuchimoto, D., Tominaga, Y., Asoh, S., Ohta, S., Kitagawa, M., Horie, H., Kadoya, T. & Nakabeppu, Y., May 1 2003, In : Cell Death and Differentiation. 10, 5, p. 496-507 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation

Villacorte, M., Suzuki, K., Hirasawa, A., Ohkawa, Y., Suyama, M., Maruyama, T., Aoki, D., Ogino, Y., Miyagawa, S., Terabayashi, T., Tomooka, Y., Nakagata, N. & Yamada, G., Jul 18 2013, In : Oncogene. 32, 29, p. 3477-3482 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

γ/δ T Cell Receptor

Yoshikai, Y., Jan 1 1991, In : MICROBIOLOGY and IMMUNOLOGY. 35, 7, p. 493-506 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

γδ T cells may dichotomously modulate infection with avirulent Salmonella choleraesuis via IFN-γ and IL-13 in mice

Naiki, Y., Nishimura, H., Itohara, S. & Yoshikai, Y., May 25 2000, In : Cellular Immunology. 202, 1, p. 61-69 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

“Radioresistant” intrathymic T cell precursors express T cell receptor Cγ4‐ and Cδ‐specific gene messages

Kishihara, K., Yoshikai, Y., Matsuzaki, G., Tomooka, S. & Nomoto, K., Jan 1 1988, In : European Journal of Immunology. 18, 6, p. 841-847 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

ミトコンドリア膜透過装置rat Tom20p cytoplasmic domainの溶液構造

Translated title of the contribution: Solution Structure of Rat Tom20p.阿部義人, 小代俊浩, 遠藤斗志也 & 神田大輔, Sep 7 1998, In : Biophysics (Japan). 38, 2, p. S5

Research output: Contribution to journalArticle

九州大学生体防御医学研究所分子機能制御学部門免疫ゲノム生物学分野

Translated title of the contribution: The roll of B cells in allergySaito, Y. & Baba, Y., Jan 1 2019, In : Japanese Journal of Allergology. 68, 6, p. 661-667 7 p.

Research output: Contribution to journalArticle

Book
10 Citations (Scopus)

C-type lectin receptors in immunity

Yamasaki, S., Jan 1 2016, Springer Japan. 215 p.

Research output: Book/ReportBook