Medical Institute of Bioregulation

Research Output 1979 2020

2018
3 Citations (Scopus)

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Sakurai, T., Uruno, T., Sugiura, Y., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fuku, Y., Jul 31 2018, In : Science Signaling. 11, 541, eaao4874.

Research output: Contribution to journal › Article

Immune Evasion
Cytokinesis
Tissue
Guanine Nucleotide Exchange Factors
Proteins
4 Citations (Scopus)

Clinical and Immunological Characterization of ICF Syndrome in Japan

Kamae, C., Imai, K., Kato, T., Okano, T., Honma, K., Nakagawa, N., Yeh, T. W., Noguchi, E., Ohara, A., Shigemura, T., Takahashi, H., Takakura, S., Hayashi, M., Honma, A., Watanabe, S., Shigemori, T., Ohara, O., Sasaki, H., Kubota, T., Morio, T. & 2 others, Kanegane, H. & Nonoyama, S., Nov 1 2018, In : Journal of Clinical Immunology. 38, 8, p. 927-937 11 p.

Research output: Contribution to journal › Article

Japan
Passive Immunization
Virus Diseases
B-Lymphocytes
T-Lymphocytes
11 Citations (Scopus)

Combined mutation of Apc, Kras, and Tgfbr2 effectively drives metastasis of intestinal cancer

Sakai, E., Nakayama, M., Oshima, H., Kouyama, Y., Niida, A., Fujii, S., Ochiai, A., Nakayama, K. I., Mimori, K., Suzuki, Y., Hong, C. P., Ock, C. Y., Kim, S. J. & Oshima, M., Mar 1 2018, In : Cancer Research. 78, 5, p. 1334-1346 13 p.

Research output: Contribution to journal › Article

Intestinal Neoplasms
Neoplasm Metastasis
Mutation
Colorectal Neoplasms
Organoids

Comparative analysis of the oligosaccharide donors (Lipid-linked oligosaccharides) for the n-oligosaccharyl transfer reaction

Taguchi, Y., Fujinami, D. & Kohda, D., Jan 1 2018, In : Trends in Glycoscience and Glycotechnology. 30, 176

Research output: Contribution to journal › Article

Oligosaccharides
Glycosylation
Asparagine
Archaea
Eukaryota
14 Citations (Scopus)

Comparison of the microbial community structure between inflamed and non-inflamed sites in patients with ulcerative colitis

Hirano, A., Umeno, J., Okamoto, Y., Shibata, H., Ogura, Y., Moriyama, T., Torisu, T., Fujioka, S., Fuyuno, Y., Kawarabayasi, Y., Matsumoto, T., Kitazono, T. & Esaki, M., Sep 2018, In : Journal of Gastroenterology and Hepatology (Australia). 33, 9, p. 1590-1597 8 p.

Research output: Contribution to journal › Article

Ulcerative Colitis
Prevotella
Neisseria
Bilophila
Leptotrichia

Correction: "UV damage-induced phosphorylation of HBO1 triggers CRL4DDB2-mediated degradation to regulate cell proliferation" [Molecular and Cellular Biology 36, 3, (2016) (394-406)] doi 10.1128/MCB.00809-15

Matsunuma, R., Niida, H., Ohhata, T., Kitagawa, K., Sakai, S., Uchida, C., Shiotani, B., Matsumoto, M., Nakayama, K. I., Ogura, H., Shiiya, N. & Kitagawa, M., Apr 1 2018, In : Molecular and cellular biology. 38, 7, e00572-17.

Research output: Contribution to journal › Comment/debate

Cell Biology
Molecular Biology
Phosphorylation
Cell Proliferation

Correlation between thyroid stimulating hormone and renal function in euthyroid residents of Japan: Results from the Kyushu and Okinawa population study (KOPS)

Tanaka, Y., Furusyo, N., Kato, Y., Ueyama, T., Yamasaki, S., Ikezaki, H., Murata, M. & Hayashi, J., Jan 1 2018, In : Journal of atherosclerosis and thrombosis. 25, 4, p. 335-343 9 p.

Research output: Contribution to journal › Article

Thyrotropin
Japan
Kidney
Population
Glomerular Filtration Rate
5 Citations (Scopus)

Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

Takizawa, Y., Tanaka, H., Machida, S., Koyama, M., Maehara, K., Ohkawa, Y., Wade, P. A., Wolf, M. & Kurumizaka, H., Jan 1 2018, In : Open Biology. 8, 3, 170255.

Research output: Contribution to journal › Article

Nucleosomes
DNA sequences
DNA
Liver
Transcription Factors
2 Citations (Scopus)

Cutting edge: B cells expressing cyclic citrullinated peptide-specific antigen receptor are tolerized in normal conditions

Yamada, H., Ozawa, T., Kishi, H., Okada, S., Nakashima, Y., Muraguchi, A. & Yoshikai, Y., Dec 15 2018, In : Journal of Immunology. 201, 12, p. 3492-3496 5 p.

Research output: Contribution to journal › Article

Antigen Receptors
B-Lymphocytes
Transgenic Mice
Immunoglobulin M
Rheumatoid Arthritis
6 Citations (Scopus)

DBTSS/DBKERO for integrated analysis of transcriptional regulation

Suzuki, A., Kawano, S., Mitsuyama, T., Suyama, M., Kanai, Y., Shirahige, K., Sasaki, H., Tokunaga, K., Tsuchihara, K., Sugano, S., Nakai, K. & Suzuki, Y., Jan 1 2018, In : Nucleic acids research. 46, D1, p. D229-D238

Research output: Contribution to journal › Article

Databases
Human Genome
Nucleic Acid Regulatory Sequences
Nanopores
Encyclopedias
11 Citations (Scopus)

Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders

Hagihara, H., Catts, V. S., Katayama, Y., Shoji, H., Takagi, T., Huang, F. L., Nakao, A., Mori, Y., Huang, K. P., Ishii, S., Graef, I. A., Nakayama, K. I., Shannon Weickert, C. & Miyakawa, T., Feb 1 2018, In : Neuropsychopharmacology. 43, 3, p. 459-468 10 p.

Research output: Contribution to journal › Article

Endophenotypes
Psychiatry
Bipolar Disorder
Brain
Schizophrenia
4 Citations (Scopus)

Dectin-2 is a C-type lectin receptor that recognizes pneumocystis and participates in innate immune responses

Kottom, T. J., Hebrink, D. M., Jenson, P. E., Marsolek, P. L., Wüthrich, M., Wang, H., Klein, B., Yamasaki, S. & Limper, A. H., Feb 2018, In : American journal of respiratory cell and molecular biology. 58, 2, p. 232-240 9 p.

Research output: Contribution to journal › Editorial

Pneumocystis
C-Type Lectins
Innate Immunity
Pneumocystis carinii
Pathogens
5 Citations (Scopus)

Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

Kunduri, G., Turner-Evans, D., Konya, Y., Izumi, Y., Nagashima, K., Lockett, S., Holthuis, J., Bamba, T., Acharya, U. & Acharya, J. K., Sep 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 38, p. E8919-E8928

Research output: Contribution to journal › Article

Neuroglia
Epilepsy
Cell Membrane
Light
Drosophila
3 Citations (Scopus)

Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3

Nakayama, S., Yumimoto, K., Kawamura, A. & Nakayama, K. I., Jan 1 2018, In : Journal of Biological Chemistry. 293, 15, p. 5705-5714 10 p.

Research output: Contribution to journal › Article

Glycogen Synthase Kinase 3
Ligases
Myelin Sheath
Ubiquitin
Transcription Factors

DegSampler: Collapsed Gibbs sampler for detecting E3 binding sites

Maruyama, O. & Matsuzaki, F., Dec 6 2018, Proceedings - 2018 IEEE 18th International Conference on Bioinformatics and Bioengineering, BIBE 2018. Institute of Electrical and Electronics Engineers Inc., p. 1-9 9 p. 8567448. (Proceedings - 2018 IEEE 18th International Conference on Bioinformatics and Bioengineering, BIBE 2018).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Binding sites
Binding Sites
Proteins
Substrates
Probability distributions

DegSampler: Collapsed Gibbs Sampler for Detecting E3 Binding Sites

Maruyama, O. & Matsuzaki, F., Dec 10 2018, p. 1-9. 9 p.

Research output: Contribution to conference › Paper

samplers
binding sites
probability distribution
proteins
ubiquitin-protein ligase
63 Citations (Scopus)

Derivation of Human Trophoblast Stem Cells

Okae, H., Toh, H., Sato, T., Hiura, H., Takahashi, S., Shirane, K., Kabayama, Y., Suyama, M., Sasaki, H. & Arima, T., Jan 4 2018, In : Cell stem cell. 22, 1, p. 50-63.e6

Research output: Contribution to journal › Article

Trophoblasts
Stem Cells
Blastocyst
Human Development
Cell Line
9 Citations (Scopus)

Development of an analytical method for polycyclic aromatic hydrocarbons in coffee beverages and dark beer using novel high-sensitivity technique of supercritical fluid chromatography/mass spectrometry

Yoshioka, T., Nagatomi, Y., Harayama, K. & Bamba, T., Jul 1 2018, In : Journal of Bioscience and Bioengineering. 126, 1, p. 126-130 5 p.

Research output: Contribution to journal › Article

Supercritical Fluid Chromatography
Beer
Coffee
Beverages
Polycyclic Aromatic Hydrocarbons
4 Citations (Scopus)

Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice

Kobori, M., Takahashi, Y., Takeda, H., Takahashi, M., Izumi, Y., Akimoto, Y., Sakurai, M., Oike, H., Nakagawa, T., Itoh, M., Bamba, T. & Kimura, T., Dec 1 2018, In : Scientific reports. 8, 1, 9081.

Research output: Contribution to journal › Article

Eukaryotic Initiation Factor-2
Eukaryotic Initiation Factors
Obese Mice
White Adipose Tissue
Curcumin
3 Citations (Scopus)

Direct reprogramming of spiral ganglion non-neuronal cells into neurons: Toward ameliorating sensorineural hearing loss by gene therapy

Noda, T., Meas, S. J., Nogami, J., Amemiya, Y., Uchi, R., Ohkawa, Y., Nishimura, K. & Dabdoub, A., Feb 14 2018, In : Frontiers in Cell and Developmental Biology. 6, FEB, 16.

Research output: Contribution to journal › Article

Spiral Ganglion
Sensorineural Hearing Loss
Genetic Therapy
Neurons
Auditory Hair Cells
1 Citation (Scopus)

Direct visualization of DNA baton pass between replication factors bound to PCNA

Mayanagi, K., Ishino, S., Shirai, T., Oyama, T., Kiyonari, S., Kohda, D., Morikawa, K. & Ishino, Y., Dec 1 2018, In : Scientific reports. 8, 1, 16209.

Research output: Contribution to journal › Article

Proliferating Cell Nuclear Antigen
Flap Endonucleases
DNA Ligases
DNA
Archaea
7 Citations (Scopus)

DNA methylation of the Klf14 gene region in whole blood cells provides prediction for the chronic inflammation in the adipose tissue

Iwaya, C., Kitajima, H., Yamamoto, K., Maeda, Y., Sonoda, N., Shibata, H. & Inoguchi, T., Mar 11 2018, In : Biochemical and Biophysical Research Communications. 497, 3, p. 908-915 8 p.

Research output: Contribution to journal › Article

DNA Methylation
Type 2 Diabetes Mellitus
Adipose Tissue
Medical problems
Blood Cells
5 Citations (Scopus)

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation

Tomino, T., Tajiri, H., Tatsuguchi, T., Shirai, T., Oisaki, K., Matsunaga, S., Sanematsu, F., Sakata, D., Yoshizumi, T., Maehara, Y., Kanai, M., Cote, J. F., Fukui, Y. & Uruno, T., Feb 26 2018, In : Biochemical and Biophysical Research Communications. 497, 1, p. 298-304 7 p.

Research output: Contribution to journal › Article

Fibroblasts
Guanine Nucleotide Exchange Factors
Cells
Guanosine Triphosphate
Mutation
40 Citations (Scopus)

Emerging role of interleukin-31 and interleukin-31 receptor in pruritus in atopic dermatitis

Furue, M., Yamamura, K., Kido-Nakahara, M., Nakahara, T. & Fukui, Y., Jan 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 1, p. 29-36 8 p.

Research output: Contribution to journal › Review article

Interleukin Receptors
Interleukins
Atopic Dermatitis
Pruritus
Skin
1 Citation (Scopus)

Erratum: In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver (Cell Systems (2018) 7(1) (118–128.e3), (S240547121830231X), (10.1016/j.cels.2018.05.013))

Kubota, H., Uda, S., Matsuzaki, F., Yamauchi, Y. & Kuroda, S., Nov 28 2018, In : Cell Systems. 7, 5, p. 562-564 3 p.

Research output: Contribution to journal › Comment/debate

Western Blotting
Insulin
Liver
1 Citation (Scopus)

Erratum: Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding (Immunity (2018) 48(6) (1119–1134.e7), (S1074761318301936) (10.1016/j.immuni.2018.04.024))

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., Oct 16 2018, In : Immunity. 49, 4, 1 p.

Research output: Contribution to journal › Comment/debate

Immunity
Transcription Factors
T-Lymphocytes
Gene Expression
proto-oncogene protein Spi-1
1 Citation (Scopus)

Expression of CRYM in different rat organs during development and its decreased expression in degenerating pyramidal tracts in amyotrophic lateral sclerosis

Hommyo, R., Suzuki, S. O., Abolhassani, N., Hamasaki, H., Shijo, M., Maeda, N., Honda, H., Nakabeppu, Y. & Iwaki, T., Jun 2018, In : Neuropathology. 38, 3, p. 247-259 13 p.

Research output: Contribution to journal › Article

Pyramidal Tracts
Amyotrophic Lateral Sclerosis
Pyramidal Cells
Kidney
Cerebral Cortex
5 Citations (Scopus)

Fetal leydig cells dedifferentiate and serve as adult leydig stem cells

Shima, Y., Miyabayashi, K., Sato, T., Suyama, M., Ohkawa, Y., Doi, M., Okamura, H. & Suzuki, K., Dec 2018, In : Development (Cambridge). 145, 23, dev169136.

Research output: Contribution to journal › Article

Adult Stem Cells
Leydig Cells
Pericytes
Essential Genes
Cell Lineage
21 Citations (Scopus)

Generation of human oogonia from induced pluripotent stem cells in vitro

Yamashiro, C., Sasaki, K., Yabuta, Y., Kojima, Y., Nakamura, T., Okamoto, I., Yokobayashi, S., Murase, Y., Ishikura, Y., Shirane, K., Sasaki, H., Yamamoto, T. & Saitou, M., Oct 19 2018, In : Science. 362, 6412, p. 356-360 5 p.

Research output: Contribution to journal › Article

Oogonia
Induced Pluripotent Stem Cells
Germ Cells
Pluripotent Stem Cells
Gametogenesis
11 Citations (Scopus)

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jan 1 2018, In : Nucleic acids research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journal › Article

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jul 27 2018, In : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journal › Article

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
16 Citations (Scopus)

Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4

Shimba, A., Cui, G., Tani-ichi, S., Ogawa, M., Abe, S., Okazaki, F., Kitano, S., Miyachi, H., Yamada, H., Hara, T., Yoshikai, Y., Nagasawa, T., Schütz, G. & Ikuta, K., Feb 20 2018, In : Immunity. 48, 2, p. 286-298.e6

Research output: Contribution to journal › Article

Interleukin-7 Receptors
Glucocorticoids
T-Lymphocytes
Adaptive Immunity
Immunosuppressive Agents
2 Citations (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., Aug 1 2018, In : Journal of Cell Science. 131, 15

Research output: Contribution to journal › Article

Ribosomal Proteins
Proteasome Endopeptidase Complex
Ubiquitin
Glutamic Acid
Down-Regulation
13 Citations (Scopus)

Hidden peptides encoded by putative noncoding RNAs

Matsumoto, A. & Nakayama, K. I., Jan 1 2018, In : Cell structure and function. 43, 1, p. 75-83 9 p.

Research output: Contribution to journal › Short survey

Untranslated RNA
Peptides
RNA
Amino Acids
Proteins
5 Citations (Scopus)

High affinity sugar ligands of C-type lectin receptor langerin

Ota, F., Hirayama, T., Kizuka, Y., Yamaguchi, Y., Fujinawa, R., Nagata, M., Ismanto, H. S., Lepenies, B., Aretz, J., Rademacher, C., Seeberger, P. H., Angata, T., Kitazume, S., Yoshida, K., Betsuyaku, T., Kida, K., Yamasaki, S. & Taniguchi, N., Jul 1 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 7, p. 1592-1601 10 p.

Research output: Contribution to journal › Article

C-Type Lectins
Keratan Sulfate
Sugars
Galactose
Ligands

Highly Accurate Detection and Identification Methodology of Xenobiotic Metabolites Using Stable Isotope Labeling, Data Mining Techniques, and Time-Dependent Profiling Based on LC/HRMS/MS

Takahashi, M., Izumi, Y., Iwahashi, F., Nakayama, Y., Iwakoshi, M., Nakao, M., Yamato, S., Fukusaki, E. & Bamba, T., Aug 7 2018, In : Analytical Chemistry. 90, 15, p. 9068-9076 9 p.

Research output: Contribution to journal › Article

Xenobiotics
Metabolites
2,4-Dichlorophenoxyacetic Acid
Isotopes
Labeling

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., Dec 1 2018, In : Nature communications. 9, 1, 1400.

Research output: Contribution to journal › Article

skeletal muscle
chromatin
Nucleosomes
regeneration
Histones
3 Citations (Scopus)

Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia

Nagao, H., Nishizawa, H., Tanaka, Y., Fukata, T., Mizushima, T., Furuno, M., Bamba, T., Tsushima, Y., Fujishima, Y., Kita, S., Funahashi, T., Maeda, N., Mori, M., Fukusaki, E. & Shimomura, I., Jul 1 2018, In : Obesity. 26, 7, p. 1168-1178 11 p.

Research output: Contribution to journal › Article

Hypoxanthine
Adipose Tissue
White Adipose Tissue
Uric Acid
Adipocytes
2 Citations (Scopus)

Identification of a candidate enhancer for DMRT3 involved in spastic cerebral palsy pathogenesis

Kubota, N., Yokoyama, T., Hoshi, N. & Suyama, M., Jan 29 2018, In : Biochemical and Biophysical Research Communications. 496, 1, p. 133-139 7 p.

Research output: Contribution to journal › Article

Retinoid X Receptors
Retinoic Acid Receptors
Cerebral Palsy
Transcription Factor 3
Genes
6 Citations (Scopus)

Identification of miR-305, a microRNA that promotes aging, and its target mRNAs in Drosophila

Ueda, M., Sato, T., Ohkawa, Y. & Inoue, Y. H., Feb 1 2018, In : Genes to Cells. 23, 2, p. 80-93 14 p.

Research output: Contribution to journal › Article

MicroRNAs
Drosophila
Messenger RNA
Diptera
Peptides
2 Citations (Scopus)

Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member

Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. & Kadokura, H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 48, p. 18421-18433 13 p.

Research output: Contribution to journal › Article

Protein Disulfide-Isomerases
Pancreas
Enzyme Precursors
Pancreatic Elastase
Substrates

Identifying metabolic elements that contribute to productivity of 1-propanol bioproduction using metabolomic analysis

Putri, S. P., Nakayama, Y., Shen, C., Noguchi, S., Nitta, K., Bamba, T., Pontrelli, S., Liao, J. & Fukusaki, E., Jul 1 2018, In : Metabolomics. 14, 7, 96.

Research output: Contribution to journal › Article

1-Propanol
Metabolomics
Threonine
Productivity
Escherichia coli
2 Citations (Scopus)

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., Dec 1 2018, In : npj Systems Biology and Applications. 4, 1, 14.

Research output: Contribution to journal › Article

Insulin
Clearance
Decrease
Diabetes Mellitus
Liver

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., 2018, In : npj Systems Biology and Applications. 4, 14.

Research output: Contribution to journal › Article

Open Access
Insulin
Liver
Serum
Type 2 Diabetes Mellitus
Glucose
5 Citations (Scopus)

Inhibiting Skp2 E3 ligase suppresses bleomycin-induced pulmonary fibrosis

Mikamo, M., Kitagawa, K., Sakai, S., Uchida, C., Ohhata, T., Nishimoto, K., Niida, H., Suzuki, S., Nakayama, K. I., Inui, N., Suda, T. & Kitagawa, M., Feb 6 2018, In : International journal of molecular sciences. 19, 2, 474.

Research output: Contribution to journal › Article

fibrosis
Ubiquitin-Protein Ligases
Pulmonary Fibrosis
Bleomycin
Cells
2 Citations (Scopus)

Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation

Tognon, C. E., Rafn, B., Cetinbas, N. M., Kamura, T., Trigo, G., Rotblat, B., Okumura, F., Matsumoto, M., Chow, C., Davare, M., Pollak, M., Mayor, T. & Sorensen, P. H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 32, p. 12502-12515 14 p.

Research output: Contribution to journal › Article

Somatomedin Receptors
Oncogene Proteins
Receptor Protein-Tyrosine Kinases
Somatomedins
Degradation
3 Citations (Scopus)

Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer

Kikutake, C., Yoshihara, M., Sato, T., Saito, D. & Suyama, M., Sep 1 2018, In : Oncotarget. 9, 70, p. 33337-33347 11 p.

Research output: Contribution to journal › Article

Alleles
Breast Neoplasms
Mutation
Neoplasms
Atlases
3 Citations (Scopus)

In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

Kubota, H., Uda, S., Matsuzaki, F., Yamauchi, Y. & Kuroda, S., Jul 25 2018, In : Cell Systems. 7, 1, p. 118-128.e3

Research output: Contribution to journal › Article

Insulin
Liver
Hormones
Homeostasis
Glucose Clamp Technique
4 Citations (Scopus)

Linear ubiquitin chain-binding domains

Fennell, L. M., Rahighi, S. & Ikeda, F., Aug 2018, In : FEBS Journal. 285, 15, p. 2746-2761 16 p.

Research output: Contribution to journal › Review article

Open Access
Ubiquitin
Cell signaling
Autophagy
Cell death
Substrates
5 Citations (Scopus)

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants

Foster, A. J., Nagata, M., Lu, X., Lynch, A. T., Omahdi, Z., Ishikawa, E., Yamasaki, S., Timmer, M. S. M. & Stocker, B. L., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 1045-1060 16 p.

Research output: Contribution to journal › Article

C-Type Lectins
Vaccines
Macrophages
Antigen-Presenting Cells
Pattern Recognition Receptors