Research Output 1979 2020

2016
2 Citations (Scopus)

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation

Uematsu, K., Okumura, F., Tonogai, S., Joo-Okumura, A., Alemayehu, D. H., Nishikimi, A., Fukui, Y., Nakatsukasa, K. & Kamura, T., Jan 1 2016, In : Journal of Cell Biology. 215, 1, 95.

Research output: Contribution to journalArticle

Microtubules
Suppressor of Cytokine Signaling Proteins
Cullin Proteins
Genome
Mitosis
48 Citations (Scopus)

CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells

Toya, M., Kobayashi, S., Kawasaki, M., Shioi, G., Kaneko, M., Ishiuchi, T., Misaki, K., Meng, W. & Takeichi, M., Jan 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 2, p. 332-337 6 p.

Research output: Contribution to journalArticle

Spectrin
Calmodulin
Microtubules
Epithelial Cells
Proteins
10 Citations (Scopus)

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

Derudder, E., Herzog, S., Labi, V., Yasuda, T., Köchert, K., Janz, M., Villunger, A., Schmidt-Supprian, M. & Rajewsky, K., May 3 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 18, p. 5065-5070 6 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Cell Count
B-Lymphocyte Subsets
B-Cell Lymphoma
Cell Differentiation
28 Citations (Scopus)

Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells

Okamoto, M., Miyata, T., Konno, D., Ueda, H. R., Kasukawa, T., Hashimoto, M., Matsuzaki, F. & Kawaguchi, A., Apr 20 2016, In : Nature communications. 7, 11349.

Research output: Contribution to journalArticle

Cell Cycle
Stem Cells
gene expression
Cells
neurons
15 Citations (Scopus)

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., Mar 2016, In : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

Research output: Contribution to journalArticle

Histone Code
Endogenous Retroviruses
Stem cells
Histones
Clustered Regularly Interspaced Short Palindromic Repeats
76 Citations (Scopus)

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T. & Nakayama, K. I., Jan 1 2016, In : Nature. 537, 7622, p. 675-679 5 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Phenotype
Transcription Factors
Genes
Brain
5 Citations (Scopus)

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

Kobayashi, W., Takaku, M., Machida, S., Tachiwana, H., Maehara, K., Ohkawa, Y. & Kurumizaka, H., Apr 7 2016, In : Scientific reports. 6, 24228.

Research output: Contribution to journalArticle

Nucleosomes
Chromatin
Recombinases
Homologous Recombination
DNA
14 Citations (Scopus)

Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes

Oka, M., Mura, S., Yamada, K., Sangel, P., Hirata, S., Maehara, K., Kawakami, K., Tachibana, T., Ohkawa, Y., Kimura, H. & Yoneda, Y., Jan 7 2016, In : eLife. 5, JANUARY2016, e09540.

Research output: Contribution to journalArticle

Homeobox Genes
Chromatin
Fusion reactions
Genes
Stem cells
17 Citations (Scopus)

Comparative analysis of archaeal lipid-linked oligosaccharides that serve as oligosaccharide donors for Asn glycosylation

Taguchi, Y., Fujinami, D. & Kohda, D., May 20 2016, In : Journal of Biological Chemistry. 291, 21, p. 11042-11054 13 p.

Research output: Contribution to journalArticle

Glycosylation
Oligosaccharides
Archaeoglobus fulgidus
Bearings (structural)
Euryarchaeota
3 Citations (Scopus)
19 Citations (Scopus)

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Behler-Janbeck, F., Takano, T., Maus, R., Stolper, J., Jonigk, D., Tort Tarrés, M., Fuehner, T., Prasse, A., Welte, T., Timmer, M. S. M., Stocker, B. L., Nakanishi, Y., Miyamoto, T., Yamasaki, S. & Maus, U. A., Dec 6 2016, In : PLoS pathogens. 12, 12, e1006038.

Research output: Contribution to journalArticle

Pneumococcal Pneumonia
C-Type Lectins
Streptococcus pneumoniae
Alveolar Macrophages
Immunity
19 Citations (Scopus)

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

Toyonaga, K., Torigoe, S., Motomura, Y., Kamichi, T., Hayashi, J. M., Morita, Y. S., Noguchi, N., Chuma, Y., Kiyohara, H., Matsuo, K., Tanaka, H., Nakagawa, Y., Sakuma, T., Ohmuraya, M., Yamamoto, T., Umemura, M., Matsuzaki, G., Yoshikai, Y., Yano, I., Miyamoto, T. & 1 others, Yamasaki, S., Dec 20 2016, In : Immunity. 45, 6, p. 1245-1257 13 p.

Research output: Contribution to journalArticle

C-Type Lectins
Mycobacterium
Infection
Chemokine CCL2
Monocytes

C-type lectin receptors in immunity

Yamasaki, S., Jan 1 2016, Springer Japan. 215 p.

Research output: Book/ReportBook

C-Type Lectins
Bearings (structural)
Immunity
Pattern Recognition Receptors
Pharmaceutical Preparations
21 Citations (Scopus)

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity

Massaad, M. J., Zhou, J., Tsuchimoto, D., Chou, J., Jabara, H., Janssen, E., Glauzy, S., Olson, B. G., Morbach, H., Ohsumi, T. K., Schmitz, K., Kyriacos, M., Kane, J., Torisu, K., Nakabeppu, Y., Notarangelo, L. D., Chouery, E., Megarbane, A., Kang, P. B., Al-Idrissi, E. & 8 others, Aldhekri, H., Meffre, E., Mizui, M., Tsokos, G. C., Manis, J. P., Al-Herz, W., Wallace, S. S. & Geha, R. S., Nov 1 2016, In : Journal of Clinical Investigation. 126, 11, p. 4219-4236 18 p.

Research output: Contribution to journalArticle

Deoxyribonuclease (Pyrimidine Dimer)
Autoimmunity
DNA Repair
B-Lymphocytes
Enzymes
86 Citations (Scopus)

De novo DNA methylation drives 5hmC accumulation in mouse zygotes

Amouroux, R., Nashun, B., Shirane, K., Nakagawa, S., Hill, P. W. S., D'Souza, Z., Nakayama, M., Matsuda, M., Turp, A., Ndjetehe, E., Encheva, V., Kudo, N. R., Koseki, H., Sasaki, H. & Hajkova, P., Jan 28 2016, In : Nature Cell Biology. 18, 2, p. 225-233 9 p.

Research output: Contribution to journalArticle

5-Methylcytosine
Zygote
DNA Methylation
Hydroxylation
Methylation
4 Citations (Scopus)

Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

Yoneshima, Y., Abolhassani, N., Iyama, T., Sakumi, K., Shiomi, N., Mori, M., Shiomi, T., Noda, T., Tsuchimoto, D. & Nakabeppu, Y., Sep 13 2016, In : Scientific reports. 6, 32849.

Research output: Contribution to journalArticle

DNA
Growth
Deamination
deoxyinosine
triphosphoric acid
6 Citations (Scopus)

Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat

Yoshihara, M., Saito, D., Sato, T., Ohara, O., Kuramoto, T. & Suyama, M., Aug 9 2016, In : BMC Genomics. 17, 1, 593.

Research output: Contribution to journalArticle

Exons
Mutation
Phenotype
Inbred Strains Rats
Exome
7 Citations (Scopus)

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

Liu, Z., Man, S. M., Zhu, Q., Vogel, P., Frase, S., Fukui, Y. & Kanneganti, T. D., Jun 13 2016, In : Scientific reports. 6, 27814.

Research output: Contribution to journalArticle

Citrobacter rodentium
Cytokinesis
Immunity
Infection
Bacteria
66 Citations (Scopus)

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Nishio, M., Sugimachi, K., Goto, H., Wang, J., Morikawa, T., Miyachi, Y., Takano, Y., Hikasa, H., Itoh, T., Suzuki, S. O., Kurihara, H., Aishima, S., Leask, A., Sasaki, T., Nakano, T., Nishina, H., Nishikawa, Y., Sekido, Y., Nakao, K., Shin-Ya, K. & 2 others, Mimori, K. & Suzuki, A., Jan 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 1, p. E71-E80

Research output: Contribution to journalArticle

Cholangiocarcinoma
Transforming Growth Factor beta
Liver Neoplasms
Liver
Phosphotransferases
3 Citations (Scopus)

Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation

Niikura, K., Horisawa, K. & Doi, N., Jan 1 2016, In : Journal of biochemistry. 159, 1, p. 123-132 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Epidermal Growth Factor Receptor
Peptides
Sea Urchins
Antibodies
7 Citations (Scopus)

Erratum: The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate (Cell Reports (2016) 15(7) (1481–1492) (S2211124716304454) (10.1016/j.celrep.2016.04.032))

Tortola, L., Nitsch, R., Bertrand, M. J. M., Kogler, M., Redouane, Y., Kozieradzki, I., Uribesalgo, I., Fennell, L. M., Daugaard, M., Klug, H., Wirnsberger, G., Wimmer, R., Perlot, T., Sarao, R., Rao, S., Hanada, T., Takahashi, N., Kernbauer, E., Demiröz, D., Lang, M. & 8 others, Superti-Furga, G., Decker, T., Pichler, A., Ikeda, F., Kroemer, G., Vandenabeele, P., Sorensen, P. H. & Penninger, J. M., Sep 20 2016, In : Cell Reports. 16, 12, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Receptors, Tumor Necrosis Factor, Type I
Tumors
Emotions
Neoplasms

Erratum: Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice (Scientific Reports (2016) 6 (22991) DOI: 10.1038/srep22991)

Matsushita, Y., Sakai, Y., Shimmura, M., Shigeto, H., Nishio, M., Akamine, S., Sanefuji, M., Ishizaki, Y., Torisu, H., Nakabeppu, Y., Suzuki, A., Takada, H. & Hara, T., Jun 10 2016, In : Scientific reports. 6, 27164.

Research output: Contribution to journalComment/debate

Erratum: New Insight into the Role of the Calvin Cycle: Reutilization of CO2 Emitted through Sugar Degradation (Scientific Reports 5 (2016) (11617) DOI: 10.1038/srep11617)

Shimizu, R., Dempo, Y., Nakayama, Y., Nakamura, S., Bamba, T., Fukusaki, E. & Fukui, T., Jun 20 2016, In : Scientific reports. 6, 27961.

Research output: Contribution to journalComment/debate

Erratum: Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome (Nature Communications (2015) 6 (7870) DOI: 10.1038/ncomms8870)

Thijssen, P. E., Ito, Y., Grillo, G., Wang, J., Velasco, G., Nitta, H., Unoki, M., Yoshihara, M., Suyama, M., Sun, Y., Lemmers, R. J. L. F., De Greef, J. C., Gennery, A., Picco, P., Kloeckener-Gruissem, B., Güngör, T., Reisli, I., Picard, C., Kebaili, K., Roquelaure, B. & 9 others, Iwai, T., Kondo, I., Kubota, T., Van Ostaijen-Ten Dam, M. M., Van Tol, M. J. D., Weemaes, C., Francastel, C., Van Der Maarel, S. M. & Sasaki, H., Jun 22 2016, In : Nature communications. 7, 12003.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Exploration of nucleosome positioning patterns in transcription factor function

Maehara, K. & Ohkawa, Y., Jan 21 2016, In : Scientific reports. 6, 19620.

Research output: Contribution to journalArticle

Nucleosomes
Transcription Factors
Chromatin
Gene Expression
DNA-Directed RNA Polymerases

FBXL12 regulates T-cell differentiation in a cell-autonomous manner

Nita, A., Nishiyama, M., Muto, Y. & Nakayama, K., May 1 2016, In : Genes to Cells. 21, 5, p. 517-524 8 p.

Research output: Contribution to journalArticle

Cell Differentiation
T-Lymphocytes
Thymus Gland
Placentation
Aldehyde Dehydrogenase
15 Citations (Scopus)

FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors

Kitade, S., Onoyama, I., Kobayashi, H., Yagi, H., Yoshida, S., Kato, M., Tsunematsu, R., Asanoma, K., Sonoda, K., Wake, N., Hata, K., Nakayama, K. I. & Kato, K., Oct 1 2016, In : Cancer Science. 107, 10, p. 1399-1405 7 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Phenotype
p53 Genes
DNA Methylation
Neoplasms
9 Citations (Scopus)

Filopodia formation by crosslinking of F-actin with fascin in two different binding manners

Aramaki, S., Mayanagi, K., Jin, M., Aoyama, K. & Yasunaga, T., Jun 1 2016, In : Cytoskeleton. 73, 7, p. 365-374 10 p.

Research output: Contribution to journalArticle

Pseudopodia
Actin Cytoskeleton
Actins
Electron Microscope Tomography
fascin

Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

Takaku, S., Niimi, N., Kadoya, T., Yako, H., Tsukamoto, M., Sakumi, K., Nakabeppu, Y., Horie, H. & Sango, K., Jun 5 2016, In : AIMS Molecular Science. 3, 3, p. 325-337 13 p.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)

Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids

Yoshimura, A., Kawamata, M., Yoshioka, Y., Katsuda, T., Kikuchi, H., Nagai, Y., Adachi, N., Numakawa, T., Kunugi, H., Ochiya, T. & Tamai, Y., Aug 19 2016, In : Scientific reports. 6, 31172.

Research output: Contribution to journalArticle

Transgenic Rats
Body Fluids
Green Fluorescent Proteins
Extracellular Vesicles
Endosomes
36 Citations (Scopus)

Global Landscape and Regulatory Principles of DNA Methylation Reprogramming for Germ Cell Specification by Mouse Pluripotent Stem Cells

Shirane, K., Kurimoto, K., Yabuta, Y., Yamaji, M., Satoh, J., Ito, S., Watanabe, A., Hayashi, K., Saitou, M. & Sasaki, H., Oct 10 2016, In : Developmental Cell. 39, 1, p. 87-103 17 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
DNA Methylation
Stem cells
Germ Cells
Cells
18 Citations (Scopus)

Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis

Urahama, T., Harada, A., Maehara, K., Horikoshi, N., Sato, K., Sato, Y., Shiraishi, K., Sugino, N., Osakabe, A., Tachiwana, H., Kagawa, W., Kimura, H., Ohkawa, Y. & Kurumizaka, H., Jan 15 2016, In : Epigenetics and Chromatin. 9, 1, 51.

Research output: Contribution to journalArticle

Nucleosomes
Transcription Initiation Site
Histones
Testis
Seminiferous Tubules
12 Citations (Scopus)

Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H. & Isaka, Y., Apr 11 2016, In : Scientific reports. 6, 24318.

Research output: Contribution to journalArticle

Acetylation
Histones
Lysine
Genes
Transcription Initiation Site
12 Citations (Scopus)

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease

Oka, S., Leon, J., Kunihiko, S., Ide, T., Kang, D., LaFerla, F. M. & Nakabeppu, Y., Nov 29 2016, In : Scientific reports. 6, 37889.

Research output: Contribution to journalArticle

Alzheimer Disease
Mitochondria
Prealbumin
Mitochondrial DNA
Oxidative Stress
9 Citations (Scopus)

Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice

Matsushita, Y., Sakai, Y., Shimmura, M., Shigeto, H., Nishio, M., Akamine, S., Sanefuji, M., Ishizaki, Y., Torisu, H., Nakabeppu, Y., Suzuki, A., Takada, H. & Hara, T., Mar 10 2016, In : Scientific reports. 6, 22991.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Premature Mortality
Malformations of Cortical Development
Epilepsy
Neurons
3 Citations (Scopus)

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., Oct 2016, In : PloS one. 11, 10, e0165473.

Research output: Contribution to journalArticle

immunoglobulin genes
Immunoglobulin Genes
hybridomas
Hybridomas
Immunoglobulins
3 Citations (Scopus)

Identification of low-abundance proteins in serum via the isolation of HSP72 complexes

Tanaka, M., Shiota, M., Nakao, T., Uemura, R., Nishi, S., Ohkawa, Y., Matsumoto, M., Yamaguchi, M., Osada-Oka, M., Inagaki, A., Takahashi, K., Nakayama, K., Gi, M., Izumi, Y., Miura, K. & Iwao, H., Mar 16 2016, In : Journal of Proteomics. 136, p. 214-221 8 p.

Research output: Contribution to journalArticle

HSP72 Heat-Shock Proteins
Blood Proteins
Multiple Myeloma
Proteins
Tumors
4 Citations (Scopus)

IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice

Wang, Y., Jiang, X., Zhu, J., Yue, D., Zhang, X., Wang, X., You, Y., Wang, B., Xu, Y., Lu, C., Sun, X. & Yoshikai, Y., Aug 22 2016, In : Scientific reports. 6, 31881.

Research output: Contribution to journalArticle

Interleukin-21 Receptors
Mucous Membrane
Inflammation
Inflammatory Bowel Diseases
Colitis
7 Citations (Scopus)

IL-21 inhibits IL-17A-producing γδ T-cell response after infection with Bacillus Calmette-Guérin via induction of apoptosis

Huang, Y., Matsumura, Y., Hatano, S., Noguchi, N., Murakami, T., Iwakura, Y., Sun, X., Ohara, N. & Yoshikai, Y., Nov 1 2016, In : Innate Immunity. 22, 8, p. 588-597 10 p.

Research output: Contribution to journalArticle

Interleukin-17
Bacillus
Apoptosis
T-Lymphocytes
Interleukin-21 Receptors
10 Citations (Scopus)

Inhibition of the Arabidopsis bHLH transcription factor by monomerization through abscisic acid-induced phosphorylation

Takahashi, Y., Kinoshita, T., Matsumoto, M. & Shimazaki, K. I., Sep 1 2016, In : The Plant journal : for cell and molecular biology. 87, 6, p. 559-567 9 p.

Research output: Contribution to journalArticle

basic helix-loop-helix transcription factors
Basic Helix-Loop-Helix Transcription Factors
Abscisic Acid
Arabidopsis
abscisic acid
5 Citations (Scopus)

Insights into the formation mechanism of chloropropanol fatty acid esters under laboratory-scale deodorization conditions

Hori, K., Hori-Koriyama, N., Tsumura, K., Fukusaki, E. & Bamba, T., Aug 1 2016, In : Journal of Bioscience and Bioengineering. 122, 2, p. 246-251 6 p.

Research output: Contribution to journalArticle

Fatty acids
Esters
Fatty Acids
Palm oil
Diglycerides
11 Citations (Scopus)

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice

Sakuraba, K., Oyamada, A., Fujimura, K., Spolski, R., Iwamoto, Y., Leonard, W. J., Yoshikai, Y. & Yamada, H., Aug 17 2016, In : Arthritis Research and Therapy. 18, 1, 188.

Research output: Contribution to journalArticle

Interleukin-21 Receptors
Experimental Arthritis
B-Lymphocytes
T-Lymphocytes
Knockout Mice
40 Citations (Scopus)

In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells

Ishikura, Y., Yabuta, Y., Ohta, H., Hayashi, K., Nakamura, T., Okamoto, I., Yamamoto, T., Kurimoto, K., Shirane, K., Sasaki, H. & Saitou, M., Dec 6 2016, In : Cell Reports. 17, 10, p. 2789-2804 16 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Stem cells
Stem Cells
Spermatogenesis
Germ Cells
1 Citation (Scopus)

In vitro selection of bispecific diabody fragments using covalent bicistronic DNA display

Nakayama, M., Komiya, S., Fujiwara, K., Horisawa, K. & Doi, N., Sep 16 2016, In : Biochemical and Biophysical Research Communications. 478, 2, p. 606-611 6 p.

Research output: Contribution to journalArticle

Bispecific Antibodies
Immunoglobulin Fragments
Display devices
DNA
Libraries
4 Citations (Scopus)

In vitro steroid profiling system for the evaluation of endocrine disruptors

Nakano, Y., Yamashita, T., Okuno, M., Fukusaki, E. & Bamba, T., Sep 1 2016, In : Journal of Bioscience and Bioengineering. 122, 3, p. 370-377 8 p.

Research output: Contribution to journalArticle

Endocrine Disruptors
Steroids
Endocrine System
Economics
Chemical Safety
17 Citations (Scopus)

IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease

Zhou, H., Yu, M., Zhao, J., Martin, B. N., Roychowdhury, S., McMullen, M. R., Wang, E., Fox, P. L., Yamasaki, S., Nagy, L. E. & Li, X., Dec 1 2016, In : Hepatology. 64, 6, p. 1978-1993 16 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptor-Associated Kinases
Alcoholic Liver Diseases
Toll-Like Receptors
Spliceosomes
Cell Death
22 Citations (Scopus)

Isolation and characterization of Fetal Leydig progenitor cells of male mice

Inoue, M., Shima, Y., Miyabayashi, K., Tokunaga, K., Sato, T., Baba, T., Ohkawa, Y., Akiyama, H., Suyama, M. & Morohashi, K. I., Mar 2016, In : Endocrinology. 157, 3, p. 1222-1233 12 p.

Research output: Contribution to journalArticle

Leydig Cells
Stem Cells
Testis
Growth Factor Receptors
Transcriptome
24 Citations (Scopus)

Kawasaki disease: a matter of innate immunity

Hara, T., Nakashima, Y., Sakai, Y., Nishio, H., Motomura, Y. & Yamasaki, S., Nov 1 2016, In : Clinical and Experimental Immunology. 186, 2, p. 134-143 10 p.

Research output: Contribution to journalReview article

Mucocutaneous Lymph Node Syndrome
Innate Immunity
Vasculitis
Nursery Schools
Inflammasomes
4 Citations (Scopus)

Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma

Terada, M., Horisawa, K., Miura, S., Takashima, Y., Ohkawa, Y., Sekiya, S., Matsuda-Ito, K. & Suzuki, A., Oct 4 2016, In : Scientific reports. 6, 34691.

Research output: Contribution to journalArticle

Kupffer Cells
Cholangiocarcinoma
Hepatocytes
Liver
Intrahepatic Bile Ducts
1 Citation (Scopus)

Laguerre filter analysis with partial least square regression reveals a priming effect of ERK and CREB on c-FOS induction

Kudo, T., Uda, S., Tsuchiya, T., Wada, T., Karasawa, Y., Fujii, M., Saito, T. H. & Kuroda, S., Aug 1 2016, In : PloS one. 11, 8, e0160548.

Research output: Contribution to journalArticle

Least-Squares Analysis
mitogen-activated protein kinase
least squares
Molecules
Immediate-Early Genes