Research Output 1979 2019

Filter
Article
2019

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes.

Haruyama, N., Kunihiko, S., Katogi, A., Tsuchimoto, D., De Luca, G., Bignami, M. & Nakabeppu, Y., Apr 19 2019, (Accepted/In press) In : Progress in Neurobiology.

Research output: Contribution to journalArticle

A chromatin integration labelling method enables epigenomic profiling with lower input

Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., Feb 1 2019, In : Nature Cell Biology. 21, 2, p. 287-296 10 p.

Research output: Contribution to journalArticle

Epigenomics
Chromatin
Chromatin Immunoprecipitation
Histone Code
Immunoprecipitation
2 Citations (Scopus)

CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome

Unoki, M., Funabiki, H., Velasco, G., Francastel, C. & Sasaki, H., Jan 2 2019, In : Journal of Clinical Investigation. 129, 1, CI99751.

Research output: Contribution to journalArticle

Chromosome Segregation
Mutation
HEK293 Cells
Chromatin
Apoptosis

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires HeS1 to bind diverse DNA sites

Noguchi, Y. T., Nakamura, M., Hino, N., Nogami, J., Tsuji, S., Sato, T., Zhang, L., Tsujikawa, K., Tanaka, T., Izawa, K., Okada, Y., Doi, T., Kokubo, H., Harada, A., Uezumi, A., Gessler, M., Ohkawa, Y. & Fukada, S. I., Feb 1 2019, In : Development (Cambridge). 146, 4, dev163618.

Research output: Contribution to journalArticle

Open Access
Muscle Cells
Stem Cells
DNA
Myogenin
Chromatin

Comparison of sequential derivatization with concurrent methods for GC/MS-based metabolomics

Miyagawa, H. & Bamba, T., Feb 1 2019, In : Journal of Bioscience and Bioengineering. 127, 2, p. 160-168 9 p.

Research output: Contribution to journalArticle

Metabolomics
Metabolites
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry

Computational investigation of the conformational dynamics in Tom20-mitochondrial presequence tethered complexes

Srivastava, A., Tama, F., Kohda, D. & Miyashita, O., Jan 1 2019, In : Proteins: Structure, Function and Bioinformatics. 87, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

Disulfides
Molecular Dynamics Simulation
Membranes
Peptides
Molecular dynamics

Development of a practical online supercritical fluid extraction–supercritical fluid chromatography/mass spectrometry system with an integrated split-flow method

Sakai, M., Hayakawa, Y., Funada, Y., Ando, T., Fukusaki, E. & Bamba, T., May 10 2019, In : Journal of Chromatography A. 1592, p. 161-172 12 p.

Research output: Contribution to journalArticle

Supercritical Fluid Chromatography
Supercritical fluids
Chromatography
Mass spectrometry
Mass Spectrometry

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis

Muto, Y., Moroishi, T., Ichihara, K., Nishiyama, M., Shimizu, H., Eguchi, H., Moriya, K., Koike, K., Mimori, K., Mori, M., Katayama, Y. & Nakayama, K., Apr 1 2019, In : Journal of Experimental Medicine. 216, 4, p. 950-965 16 p.

Research output: Contribution to journalArticle

Open Access
Carcinogenesis
Homeostasis
Iron
Iron Overload
Liver

Elucidating functions of DP1 and DP2 subunits from the Thermococcus kodakarensis family D DNA polymerase

Takashima, N., Ishino, S., Oki, K., Takafuji, M., Yamagami, T., Matsuo, R., Mayanagi, K. & Ishino, Y., Jan 22 2019, In : Extremophiles. 23, 1, p. 161-172 12 p.

Research output: Contribution to journalArticle

Thermococcus
Transcription Factor DP1
Archaea
DNA-Directed DNA Polymerase
DNA

Gas chromatography-mass spectrometry metabolomics-based prediction of potato tuber sprouting during long-term storage

Fukuda, T., Takamatsu, K., Bamba, T. & Fukusaki, E., Jan 1 2019, In : Journal of Bioscience and Bioengineering.

Research output: Contribution to journalArticle

Metabolomics
Biomarkers
Solanum tuberosum
Gas chromatography
Gas Chromatography-Mass Spectrometry

Germline mutation: de novo mutation in reproductive lineage cells

Kunihiko, S., Apr 9 2019, In : Genes & genetic systems. 94, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

Open Access
Germ-Line Mutation
Mutation Rate
Genome
Mutation
Cell Division

Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection

Au Yeung, W. K., Brind'Amour, J., Hatano, Y., Yamagata, K., Feil, R., Lorincz, M. C., Tachibana, M., Shinkai, Y. & Sasaki, H., Apr 2 2019, In : Cell Reports. 27, 1, p. 282-293.e4

Research output: Contribution to journalArticle

Open Access
Methylation
Oocytes
Chromatin
Chromosome Segregation
Chromosomes

Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., Feb 1 2019, In : Anticancer research. 39, 2, p. 671-677 7 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Exome

Identification of Metabolites Associated with Onset of CAD in Diabetic Patients Using CE-MS Analysis: A Pilot Study

Omori, K., Katakami, N., Yamamoto, Y., Ninomiya, H., Takahara, M., Matsuoka, T. A., Bamba, T., Fukusaki, E. & Shimomura, I., Mar 1 2019, In : Journal of atherosclerosis and thrombosis. 26, 3, p. 233-245 13 p.

Research output: Contribution to journalArticle

Open Access
Metabolites
Coronary Artery Disease
Medical problems
Arteries
Galactosamine

Identification of novel serum markers for the progression of coronary atherosclerosis in WHHLMI rabbits, an animal model of familial hypercholesterolemia

Shiomi, M., Takeda, H., Irino, Y., Kimura, N., Yamada, S., Kuniyoshi, N., Kikumori, A., Koike, Y., Koike, T., Yoshida, M., Izumi, Y., Shinohara, M., Bamba, T. & Ishida, T., May 1 2019, In : Atherosclerosis. 284, p. 18-23 6 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Coronary Artery Disease
Animal Models
Biomarkers
Rabbits

Locomotor Training Increases Synaptic Structure With High NGL-2 Expression After Spinal Cord Hemisection

Kobayakawa, K., DePetro, K. A., Zhong, H., Pham, B., Hara, M., Harada, A., Nogami, J., Ohkawa, Y. & Edgerton, V. R., Jan 1 2019, In : Neurorehabilitation and Neural Repair.

Research output: Contribution to journalArticle

Spinal Cord
Synapses
RNA
Synaptophysin
Gene Ontology

miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation

Kozuka, T., Omori, Y., Watanabe, S., Tarusawa, E., Yamamoto, H., Chaya, T., Furuhashi, M., Morita, M., Sato, T., Hirose, S., Ohkawa, Y., Yoshimura, Y., Hikida, T. & Furukawa, T., Dec 1 2019, In : Scientific reports. 9, 1, 3445.

Research output: Contribution to journalArticle

Prefrontal Cortex
MicroRNAs
Central Nervous System
Methamphetamine
Pyramidal Cells

Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones

Katoh-Fukui, Y., Baba, T., Sato, T., Otake, H., Nagakui-Noguchi, Y., Shindo, M., Suyama, M., Ohkawa, Y., Tsumura, H., Morohashi, K-I. & Fukami, M., Mar 1 2019, In : Bone. 120, p. 219-231 13 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone and Bones
Cell Lineage
Genes
Polycomb-Group Proteins
1 Citation (Scopus)

Novel components of germline sex determination acting downstream of foxl3 in medaka

Kikuchi, M., Nishimura, T., Saito, D., Shigenobu, S., Takada, R., Gutierrez-Triana, J. A., Cerdán, J. L. M., Takada, S., Wittbrodt, J., Suyama, M. & Tanaka, M., Jan 1 2019, In : Developmental Biology. 445, 1, p. 80-89 10 p.

Research output: Contribution to journalArticle

Oryzias
Germ Cells
Sex Differentiation
Chromatids
Ubiquitin-Protein Ligases

Pathological changes of distal motor neurons after complete spinal cord injury

Yokota, K., Kubota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Maeda, T., Katoh, H., Ohkawa, Y., Nakashima, Y. & Okada, S., Jan 9 2019, In : Molecular Brain. 12, 1, 4.

Research output: Contribution to journalArticle

Motor Neurons
Spinal Cord Injuries
Spinal Cord
Microdissection
Thoracic Injuries
Heavy Ion Radiotherapy
Spontaneous Fractures
Single-Photon Emission-Computed Tomography
Bone and Bones
Bone Remodeling

Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells

Shimizu, H., Takeishi, S., Nakatsumi, H. & Nakayama, K., Feb 21 2019, In : JCI insight. 4, 4

Research output: Contribution to journalArticle

Neoplasms
Breast Neoplasms
Drug Therapy
Paclitaxel
Heterografts
Arm Injuries
Ossification of Posterior Longitudinal Ligament
Pectoralis Muscles
Prone Position
Brachial Plexus

Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data

Kawata, K., Yugi, K., Hatano, A., Kokaji, T., Tomizawa, Y., Fujii, M., Uda, S., Kubota, H., Matsumoto, M., Nakayama, K. & Kuroda, S., Jan 1 2019, In : Genes to Cells. 24, 1, p. 82-93 12 p.

Research output: Contribution to journalArticle

Insulin
Phosphorylation
Proteins
Protein Kinases
Hepatocellular Carcinoma

Spinocerebellar ataxia 27 with a novel nonsense variant (Lys177X) in FGF14

Miura, S., Kosaka, K., Fujioka, R., Uchiyama, Y., Shimojo, T., Morikawa, T., Irie, A., Taniwaki, T. & Shibata, H., Mar 1 2019, In : European Journal of Medical Genetics. 62, 3, p. 172-176 5 p.

Research output: Contribution to journalArticle

Dysarthria
Ataxia
Gait
Progressive Myoclonic Epilepsy
Genes

The acute phase serum zinc concentration is a reliable biomarker for predicting the functional outcome after spinal cord injury

Kijima, K., Kubota, K., Hara, M., Kobayakawa, K., Yokota, K., Saito, T., Yoshizaki, S., Maeda, T., Konno, D., Matsumoto, Y., Nakashima, Y. & Okada, S., Mar 1 2019, In : EBioMedicine. 41, p. 659-669 11 p.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Spinal Cord Injuries
Zinc
Serum
Patient treatment
1 Citation (Scopus)

The jpost environment: An integrated proteomics data repository and database

Moriya, Y., Kawano, S., Okuda, S., Watanabe, Y., Matsumoto, M., Takami, T., Kobayashi, D., Yamanouchi, Y., Araki, N., Yoshizawa, A. C., Tabata, T., Iwasaki, M., Sugiyama, N., Tanaka, S., Goto, S. & Ishihama, Y., Jan 8 2019, In : Nucleic acids research. 47, D1, p. D1218-D1224

Research output: Contribution to journalArticle

Proteomics
Databases
Mass Spectrometry
Peptides
Proteome

Transcriptome profiling of refractory atopic keratoconjunctivitis by RNA sequencing

Matsuda, A., Asada, Y., Suita, N., Iwamoto, S., Hirakata, T., Yokoi, N., Ohkawa, Y., Okada, Y., Yokomizo, T. & Ebihara, N., Apr 1 2019, In : Journal of Allergy and Clinical Immunology. 143, 4, p. 1610-1614.e6

Research output: Contribution to journalArticle

Keratoconjunctivitis
RNA Sequence Analysis
Gene Expression Profiling

Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans

Hada, K., Hirota, K., Inanobe, A., Kako, K., Miyata, M., Araoi, S., Matsumoto, M., Ohta, R., Arisawa, M., Daitoku, H., Hanada, T. & Fukamizu, A., Jan 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3091-3099 9 p.

Research output: Contribution to journalArticle

Animal cell culture
Acetylation
Reaction intermediates
Citric Acid Cycle
Mitochondrial Proteins
2018
2 Citations (Scopus)

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

Matsuda, S., Yasukawa, T., Sakaguchi, Y., Ichiyanagi, K., Unoki, M., Gotou, K., Fukuda, K., Sasaki, H., Suzuki, T. & Kang, D., 2018, In : Scientific Reports. 8, 1

Research output: Contribution to journalArticle

Open Access

Acetaldehyde administrationinduces salsolinol formation in vivo in the dorsal striatum of Aldh2-knockout and C57BL/6N mice

Ito, A., Jamal, M., Ameno, K., Tanaka, N., Takakura, A., Kawamoto, T., Kitagawa, K., Nakayama, K., Matsumoto, A., Miki, T. & Kinoshita, H., Oct 15 2018, In : Neuroscience Letters. 685, p. 50-54 5 p.

Research output: Contribution to journalArticle

Acetaldehyde
Inbred C57BL Mouse
Knockout Mice
Dopamine
Serotonin
6 Citations (Scopus)

Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release

Obata, Y., Kita, S., Koyama, Y., Fukuda, S., Takeda, H., Takahashi, M., Fujishima, Y., Nagao, H., Masuda, S., Tanaka, Y., Nakamura, Y., Nishizawa, H., Funahashi, T., Ranscht, B., Izumi, Y., Bamba, T., Fukusaki, E., Hanayama, R., Shimada, S., Maeda, N. & 1 othersShimomura, I., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
Exosomes
Ceramides
Adiponectin
Aorta
Multivesicular Bodies
2 Citations (Scopus)

Alterations in Docosahexaenoic Acid-Related Lipid Cascades in Inflammatory Bowel Disease Model Mice

Nishiumi, S., Izumi, Y. & Yoshida, M., Jun 1 2018, In : Digestive Diseases and Sciences. 63, 6, p. 1485-1496 12 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Inflammatory Bowel Diseases
Knockout Mice
Interleukin-10
Lipids
1 Citation (Scopus)

Ameliorating effects of D-47, a newly developed compound, on lipid metabolism in an animal model of familial hypercholesterolemia (WHHLMI rabbits)

Tamura, S., Koike, Y., Takeda, H., Koike, T., Izumi, Y., Nagasaka, R., Tsunoda, T., Tori, M., Ogawa, K., Bamba, T. & Shiomi, M., Mar 5 2018, In : European Journal of Pharmacology. 822, p. 147-153 7 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Lipid Metabolism
Animal Models
Rabbits
Fats
4 Citations (Scopus)

A molecular roadmap for the emergence of early-embryonic-like cells in culture

Rodriguez-Terrones, D., Gaume, X., Ishiuchi, T., Weiss, A., Kopp, A., Kruse, K., Penning, A., Vaquerizas, J. M., Brino, L. & Torres-Padilla, M. E., Jan 1 2018, In : Nature genetics. 50, 1, p. 106-119 14 p.

Research output: Contribution to journalArticle

Cell Culture Techniques
Embryonic Stem Cells
Epigenomics
Pluripotent Stem Cells
Small Interfering RNA

An albino mutant of the Japanese rat snake (Elaphe climacophora) carries a nonsense mutation in the tyrosinase gene

Iwanishi, S., Zaitsu, S., Shibata, H. & Nitasaka, E., Jan 1 2018, In : Genes and Genetic Systems. 93, 4, p. 163-167 5 p.

Research output: Contribution to journalArticle

Monophenol Monooxygenase
Snakes
Nonsense Codon
Pets
Genes

A new targeted capture method using bacterial artificial chromosome (BAC) libraries as baits for sequencing relatively large genes

Koganebuchi, K., Gakuhari, T., Takeshima, H., Sato, K., Fujii, K., Kumabe, T., Kasagi, S., Sato, T., Tajima, A., Shibata, H., Ogawa, M. & Oota, H., Jul 1 2018, In : PloS one. 13, 7, e0200170.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
bacterial artificial chromosomes
Chromosomes
baits
Genes

An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma

Sakurada, A., Miyanishi, K., Tanaka, S., Sato, M., Sakamoto, H., Kawano, Y., Takada, K., Nakabeppu, Y., Kobune, M. & Kato, J., Dec 1 2018, In : Free Radical Biology and Medicine. 129, p. 88-96 9 p.

Research output: Contribution to journalArticle

Polymorphism
Single Nucleotide Polymorphism
Hepatocellular Carcinoma
Nucleotides
Genes
1 Citation (Scopus)

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Fujii, T., Yamasaki, R., Iinuma, K., Tsuchimoto, D., Hayashi, Y., Saitoh, B. Y., Matsushita, T., Kido, M. A., Aishima, S., Nakanishi, H., Nakabeppu, Y. & Kira, J. I., Aug 2018, In : Annals of Neurology. 84, 2, p. 208-224 17 p.

Research output: Contribution to journalArticle

Neuralgia
Autoantibodies
Spinal Ganglia
Neurons
Unmyelinated Nerve Fibers
4 Citations (Scopus)

Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi

Shijo, M., Honda, H., Suzuki, S., Hamasaki, H., Hokama, M., Abolhassani, N., Nakabeppu, Y., Ninomiya, T., Kitazono, T. & Iwaki, T., Jan 2018, In : Brain Pathology. 28, 1, p. 58-71 14 p.

Research output: Contribution to journalArticle

Adipocytes
Hippocampus
Carrier Proteins
Pathology
Alzheimer Disease
2 Citations (Scopus)

Association of decreased percentage of Vδ2+Vγ9+ γδ T cells with disease severity in multiple sclerosis

Maimaitijiang, G., Shinoda, K., nakamura, Y., Masaki, K., Matsushita, T., Isobe, N., Yamasaki, R., Yoshikai, Y. & Kira, J-I., Apr 10 2018, In : Frontiers in Immunology. 9, APR, 748.

Research output: Contribution to journalArticle

Multiple Sclerosis
T-Lymphocytes
Interferons
T-Cell Receptor Genes
T-Lymphocyte Gene Rearrangement

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Hosokawa, H., Romero-Wolf, M., Yui, M. A., Ungerbäck, J., Quiloan, M. L. G., Matsumoto, M., Nakayama, K., Tanaka, T. & Rothenberg, E. V., Dec 1 2018, In : Nature Immunology. 19, 12, p. 1427-1440 14 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Gene Regulatory Networks
Genes
Transcription Factors
Proteomics

Biochemical characterization of CYP505D6, a self-sufficient cytochrome P450 from the white-rot fungus Phanerochaete chrysosporium

Sakai, K., Matsuzaki, F., Wise, L., Sakai, Y., Jindou, S., Ichinose, H., Takaya, N., Kato, M., Wariishi, H. & Shimizu, M., Nov 1 2018, In : Applied and Environmental Microbiology. 84, 22, e01091-18.

Research output: Contribution to journalArticle

Phanerochaete
Phanerochaete chrysosporium
white-rot fungi
hydroxylation
Hydroxylation
2 Citations (Scopus)

Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome

Arimura, Y., Ikura, M., Fujita, R., Noda, M., Kobayashi, W., Horikoshi, N., Sun, J., Shi, L., Kusakabe, M., Harata, M., Ohkawa, Y., Tashiro, S., Kimura, H., Ikura, T. & Kurumizaka, H., Nov 2 2018, In : Nucleic acids research. 46, 19, p. 10007-10018 12 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Mutation
Neoplasms
Chromatin
1 Citation (Scopus)

Cell Aggregation Culture Induces Functional Differentiation of Induced Hepatocyte-like Cells through Activation of Hippo Signaling

Yamamoto, J., Udono, M., Miura, S., Sekiya, S. & Suzuki, A., Oct 2 2018, In : Cell Reports. 25, 1, p. 183-198 16 p.

Research output: Contribution to journalArticle

Cell Aggregation
Hepatocytes
Agglomeration
Cell Culture Techniques
Chemical activation
1 Citation (Scopus)
Autistic Disorder
Brain
Biological Phenomena
Therapeutics
Autism Spectrum Disorder
1 Citation (Scopus)

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Sakurai, T., Uruno, T., Sugiura, Y., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fukui, Y., Jul 31 2018, In : Science Signaling. 11, 541, eaao4874.

Research output: Contribution to journalArticle

Immune Evasion
Cytokinesis
Tissue
Guanine Nucleotide Exchange Factors
Proteins

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Sakurai, T., Uruno, T., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fukui, Y., Jul 31 2018, In : Science Signaling. 11, 541

Research output: Contribution to journalArticle

Immune Evasion
Cytokinesis
Tissue
Guanine Nucleotide Exchange Factors
Proteins
1 Citation (Scopus)

Clinical and Immunological Characterization of ICF Syndrome in Japan

Kamae, C., Imai, K., Kato, T., Okano, T., Honma, K., Nakagawa, N., Yeh, T. W., Noguchi, E., Ohara, A., Shigemura, T., Takahashi, H., Takakura, S., Hayashi, M., Honma, A., Watanabe, S., Shigemori, T., Ohara, O., Sasaki, H., Kubota, T., Morio, T. & 2 othersKanegane, H. & Nonoyama, S., Nov 1 2018, In : Journal of Clinical Immunology. 38, 8, p. 927-937 11 p.

Research output: Contribution to journalArticle

Japan
Passive Immunization
Virus Diseases
B-Lymphocytes
T-Lymphocytes
4 Citations (Scopus)

Combined mutation of Apc, Kras, and Tgfbr2 effectively drives metastasis of intestinal cancer

Sakai, E., Nakayama, M., Oshima, H., Kouyama, Y., Niida, A., Fujii, S., Ochiai, A., Nakayama, K., Mimori, K., Suzuki, Y., Hong, C. P., Ock, C. Y., Kim, S. J. & Oshima, M., Mar 1 2018, In : Cancer Research. 78, 5, p. 1334-1346 13 p.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Neoplasm Metastasis
Mutation
Colorectal Neoplasms
Organoids