Research Output 1979 2019

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Review article
2019
6 Citations (Scopus)

Genomic Imprinting and Physiological Processes in Mammals

the Erice Imprinting Group, Feb 21 2019, In : Cell. 176, 5, p. 952-965 14 p.

Research output: Contribution to journalReview article

Physiological Phenomena
Genomic Imprinting
Mammals
Physiology
Genes

Potentials of C-C motif chemokine 2–C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents

Yumimoto, K., Sugiyama, S., Mimori, K. & Nakayama, K., Jul 1 2019, In : Cancer Science. 110, 7, p. 2090-2099 10 p.

Research output: Contribution to journalReview article

Open Access
C Chemokines
CC Chemokines
Chemokine Receptors
Antineoplastic Agents
Inflammation
6 Citations (Scopus)

Roles of ubiquitin in autophagy and cell death

Gómez-Díaz, C. & Ikeda, F., Sep 1 2019, In : Seminars in Cell and Developmental Biology. 93, p. 125-135 11 p.

Research output: Contribution to journalReview article

Open Access
Autophagy
Ubiquitin
Cell Death
Cell Survival
Garbage
2018
4 Citations (Scopus)

Brief summary of the current protocols for generating intestinal organoids

Miura, S. & Suzuki, A., Aug 1 2018, In : Development Growth and Differentiation. 60, 6, p. 387-392 6 p.

Research output: Contribution to journalReview article

Organoids
Intestinal Diseases
Epithelial Cells
Intestines
Food
34 Citations (Scopus)
Interleukin Receptors
Interleukins
Atopic Dermatitis
Pruritus
Skin
4 Citations (Scopus)

Linear ubiquitin chain-binding domains

Fennell, L. M., Rahighi, S. & Ikeda, F., Aug 1 2018, In : FEBS Journal. 285, 15, p. 2746-2761 16 p.

Research output: Contribution to journalReview article

Open Access
Ubiquitin
Cell signaling
Autophagy
Cell death
Substrates
3 Citations (Scopus)

Lymphatics in the liver

Tanaka, M. & Iwakiri, Y., Aug 1 2018, In : Current Opinion in Immunology. 53, p. 137-142 6 p.

Research output: Contribution to journalReview article

Lymphatic System
Liver
Liver Diseases
Lymphangiogenesis
Lymphatic Vessels
5 Citations (Scopus)

The promise of targeted proteomics for quantitative network biology

Matsumoto, M. & Nakayama, K., Dec 1 2018, In : Current Opinion in Biotechnology. 54, p. 88-97 10 p.

Research output: Contribution to journalReview article

Proteomics
Proteins
Assays
Biological Phenomena
Recombinant proteins
7 Citations (Scopus)
Carrier Proteins
Binding Sites
Ligands
Biological Phenomena
Amino Acid Motifs
2017
1 Citation (Scopus)

Cell fate modification toward the hepatic lineage by extrinsic factors

Kawamata, M. & Suzuki, A., Jul 1 2017, In : Journal of Biochemistry. 162, 1, p. 11-16 6 p.

Research output: Contribution to journalReview article

Stem cells
Liver
Hepatocytes
Induced Pluripotent Stem Cells
Fibroblasts
6 Citations (Scopus)

C-type lectin receptors in anti-fungal immunity

Shiokawa, M., Yamasaki, S. & Saijo, S., Dec 1 2017, In : Current Opinion in Microbiology. 40, p. 123-130 8 p.

Research output: Contribution to journalReview article

C-Type Lectins
Immunity
Immune System
Ligands
Mycoses
6 Citations (Scopus)

Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway

Nishio, M., Maehama, T., Goto, H., Nakatani, K., Kato, W., Omori, H., Miyachi, Y., Togashi, H., Shimono, Y. & Suzuki, A., Jan 1 2017, In : Genes to Cells. 22, 1, p. 6-31 26 p.

Research output: Contribution to journalReview article

Cell Polarity
Crowding
Extracellular Matrix
Neoplasms
Carcinogenesis
16 Citations (Scopus)

MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?

Nakabeppu, Y., Ohta, E. & Abolhassani, N., Jun 1 2017, In : Free Radical Biology and Medicine. 107, p. 151-158 8 p.

Research output: Contribution to journalReview article

Nucleotides
Genes
Genome
Knockout Mice
DNA Glycosylases
27 Citations (Scopus)

Recognition of Mycobacterial Lipids by Immune Receptors

Ishikawa, E., Mori, D. & Yamasaki, S., Jan 1 2017, In : Trends in Immunology. 38, 1, p. 66-76 11 p.

Research output: Contribution to journalReview article

Mycobacterium
Glycolipids
Lipids
Immunoreceptor Tyrosine-Based Activation Motif
C-Type Lectins
3 Citations (Scopus)

Temporal regulation of chromatin during myoblast differentiation

Harada, A., Ohkawa, Y. & Imbalzano, A. N., Dec 1 2017, In : Seminars in Cell and Developmental Biology. 72, p. 77-86 10 p.

Research output: Contribution to journalReview article

Myoblasts
Chromatin
Transcription Factors
Histones
Genes

The role of serine/threonine kinase, protein kinase D, in thymocyte development

Ishikawa, E. & Yamasaki, S., Jan 1 2017, In : Seikagaku. 89, 5, p. 748-751 4 p.

Research output: Contribution to journalReview article

protein kinase D
2016
11 Citations (Scopus)

Analysis of cellular signal transduction from an information theoretic approach

Uda, S. & Kuroda, S., Mar 1 2016, In : Seminars in Cell and Developmental Biology. 51, p. 24-31 8 p.

Research output: Contribution to journalReview article

Signal Transduction
Information Theory
Cell Differentiation
Cell Death
Cell Proliferation

Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

Takaku, S., Niimi, N., Kadoya, T., Yako, H., Tsukamoto, M., Sakumi, K., Nakabeppu, Y., Horie, H. & Sango, K., Jun 5 2016, In : AIMS Molecular Science. 3, 3, p. 325-337 13 p.

Research output: Contribution to journalReview article

Open Access
21 Citations (Scopus)

Kawasaki disease: a matter of innate immunity

Hara, T., Nakashima, Y., Sakai, Y., Nishio, H., Motomura, Y. & Yamasaki, S., Nov 1 2016, In : Clinical and Experimental Immunology. 186, 2, p. 134-143 10 p.

Research output: Contribution to journalReview article

Mucocutaneous Lymph Node Syndrome
Innate Immunity
Vasculitis
Nursery Schools
Inflammasomes
34 Citations (Scopus)

To wake up cancer stem cells, or to let them sleep, that is the question

Takeishi, S. & Nakayama, K., Jul 1 2016, In : Cancer Science. 107, 7, p. 875-881 7 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Sleep
Cell Cycle
Stem Cell Niche
Therapeutics
67 Citations (Scopus)

Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple 'Omic' Layers

Yugi, K., Kubota, H., Hatano, A. & Kuroda, S., Apr 1 2016, In : Trends in biotechnology. 34, 4, p. 276-290 15 p.

Research output: Contribution to journalReview article

Data integration
Metabolism
Life Style
Technology
Phenotype
2015
6 Citations (Scopus)
Hepatocytes
Liver
Cell Tracking
Cell Lineage
Tamoxifen
4 Citations (Scopus)

MBSJ MCC young scientist award 2012 liver regeneration: A unique and flexible reaction depending on the type of injury

Suzuki, A., Feb 1 2015, In : Genes to Cells. 20, 2, p. 77-84 8 p.

Research output: Contribution to journalReview article

Liver Regeneration
Liver
Wounds and Injuries
Hepatocytes
Living Donors
2014

[Mitochondrial quality control and regulation of neuronal function].

Shirane, M., 2014, In : Seikagaku. The Journal of Japanese Biochemical Society. 86, 4, p. 479-482 4 p.

Research output: Contribution to journalReview article

Biological Transport
Tacrolimus Binding Proteins
Molecular Chaperones
Quality Control
Mitochondria
20 Citations (Scopus)

Calcium signaling in B cells: Regulation of cytosolic Ca2+ increase and its sensor molecules, STIM1 and STIM2

Baba, Y., Matsumoto, M. & Kurosaki, T., Dec 1 2014, In : Molecular Immunology. 62, 2, p. 339-343 5 p.

Research output: Contribution to journalReview article

Calcium Signaling
Endoplasmic Reticulum
B-Lymphocytes
Calcium
Calcium-Sensing Receptors
72 Citations (Scopus)
nucleotides
DNA Glycosylases
Nucleotides
Cell Survival
Carcinogenesis
32 Citations (Scopus)

Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells.

Takeishi, S. & Nakayama, K., Jan 1 2014, In : British journal of cancer. 111, 6, p. 1054-1059 6 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Maintenance
Cell Cycle
Stem Cells
Neoplasms
18 Citations (Scopus)

Specific and quantitative labeling of biomolecules using click chemistry

Horisawa, K., Jan 1 2014, In : Frontiers in Physiology. 5, Nov, 457.

Research output: Contribution to journalReview article

Click Chemistry
Proteins
Systems Biology
Cross Reactions
Cycloaddition Reaction
2013
5 Citations (Scopus)

Artificial induction and disease-related conversion of the hepatic fate

Suzuki, A., Oct 1 2013, In : Current Opinion in Genetics and Development. 23, 5, p. 579-584 6 p.

Research output: Contribution to journalReview article

Hepatocytes
Liver
Liver Diseases
Transcription Factors
Tissue Transplantation
37 Citations (Scopus)

Immune regulatory functions of DOCK family proteins in health and disease

Nishikimi, A., Kukimoto-Niino, M., Yokoyama, S. & Fukui, Y., Sep 10 2013, In : Experimental Cell Research. 319, 15, p. 2343-2349 7 p.

Research output: Contribution to journalReview article

Guanine Nucleotide Exchange Factors
Health
Proteins
PDZ Domains
rho GTP-Binding Proteins
3 Citations (Scopus)

Integrated view of the human chromosome x-centric proteome project

Yamamoto, T., Nakayama, K., Hirano, H., Tomonaga, T., Ishihama, Y., Yamada, T., Kondo, T., Kodera, Y., Sato, Y., Araki, N., Mamitsuka, H. & Goshima, N., Jan 4 2013, In : Journal of Proteome Research. 12, 1, p. 58-61 4 p.

Research output: Contribution to journalReview article

Human Chromosomes
X Chromosome
Proteome
Chromosomes
Antibodies
39 Citations (Scopus)

Nemo-like kinase, a multifaceted cell signaling regulator

Ishitani, T. & Ishitani, S., Jan 1 2013, In : Cellular Signalling. 25, 1, p. 190-197 8 p.

Research output: Contribution to journalReview article

Phosphotransferases
Catenins
Activins
Wnt Signaling Pathway
Mitogen-Activated Protein Kinase Kinases
15 Citations (Scopus)

Regulation of organogenesis and stem cell properties by T-box transcription factors

Takashima, Y. & Suzuki, A., Oct 1 2013, In : Cellular and Molecular Life Sciences. 70, 20, p. 3929-3945 17 p.

Research output: Contribution to journalReview article

Organogenesis
Transcription Factors
Stem Cells
Induced Pluripotent Stem Cells
Regenerative Medicine
20 Citations (Scopus)

Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells

Matsumoto, A. & Nakayama, K., Feb 1 2013, In : Biochimica et Biophysica Acta - General Subjects. 1830, 2, p. 2335-2344 10 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Stem cells
Cell Cycle
Cells
Maintenance
2012
12 Citations (Scopus)

Close link between development and function of gamma-delta T cells

Shibata, K., Apr 1 2012, In : MICROBIOLOGY and IMMUNOLOGY. 56, 4, p. 217-227 11 p.

Research output: Contribution to journalReview article

Somatostatin-Secreting Cells
T-Lymphocytes
Thymus Gland
Interleukin-17
T-Lymphocyte Subsets
1 Citation (Scopus)

Comprehensive study of protein ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M. & Nakayama, K., Dec 1 2012, In : Seikagaku. 84, 6, p. 479-487 9 p.

Research output: Contribution to journalReview article

Ubiquitination
Ubiquitin
Lysine
Proteins
57 Citations (Scopus)

Genomic imprinting and its relevance to congenital disease, infertility, molar pregnancy and induced pluripotent stem cell

Tomizawa, S. I. & Sasaki, H., Feb 1 2012, In : Journal of Human Genetics. 57, 2, p. 84-91 8 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Hydatidiform Mole
Induced Pluripotent Stem Cells
Infertility
Maintenance
1 Citation (Scopus)
Hepatocyte Nuclear Factor 3-gamma
Hepatocyte Nuclear Factor 3-alpha
Hepatocyte Nuclear Factor 6
Hepatocyte Nuclear Factor 3-beta
Tumor Suppressor Proteins
24 Citations (Scopus)

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

Mori, T., Ikeda, D. D., Yamaguchi, Y. & Unoki, M., Jun 4 2012, In : FEBS Letters. 586, 11, p. 1570-1583 14 p.

Research output: Contribution to journalReview article

Epigenomics
Cell Cycle
Cells
Ubiquitin
Tumors
3 Citations (Scopus)

Protein kinase NLK, that fine-tunes the activity of multiple intracellular signaling pathways

Ishitani, T., 2012, In : Seikagaku. The Journal of Japanese Biochemical Society. 84, 1, p. 39-42 4 p.

Research output: Contribution to journalReview article

Intracellular Signaling Peptides and Proteins
Lithium Chloride
Signal transduction
Phosphorylation
Protein-Serine-Threonine Kinases

The mechanism controlling leukocyte trafficking for acquired immune responses

Fukui, Y., Dec 1 2012, In : Seikagaku. 84, 3, p. 189-194 6 p.

Research output: Contribution to journalReview article

rap1 GTP-Binding Proteins
cdc42 GTP-Binding Protein
rac GTP-Binding Proteins
rho GTP-Binding Proteins
Chemokine Receptors
28 Citations (Scopus)
Neurodegenerative diseases
Neurodegenerative Diseases
Oxidation-Reduction
Antioxidants
Gases
2011

[Studies of T cells for better understanding of immunity and allergy].

Yoshikai, Y., Jan 1 2011, In : Nihon Jibiinkoka Gakkai kaiho. 114, 6, p. 539-546 8 p.

Research output: Contribution to journalReview article

Immunity
Hypersensitivity
T-Lymphocytes
40 Citations (Scopus)

DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis

Oka, S. & Nakabeppu, Y., Apr 1 2011, In : Cancer Science. 102, 4, p. 677-682 6 p.

Research output: Contribution to journalReview article

DNA Glycosylases
Carcinogenesis
Oxidative Stress
Cell Death
DNA
75 Citations (Scopus)

Genomic imprinting in mammals: Its life cycle, molecular mechanisms and reprogramming

Li, Y. & Sasaki, H., Mar 1 2011, In : Cell Research. 21, 3, p. 466-473 8 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Life Cycle Stages
Epigenomics
Mammals
Gametogenesis
32 Citations (Scopus)

Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity

Ohnmacht, C., Marques, R., Presley, L., Sawa, S., Lochner, M. & Eberl, G., May 1 2011, In : Cellular Microbiology. 13, 5, p. 653-659 7 p.

Research output: Contribution to journalReview article

Open Access
Immune System
Immunity
Intestines
Dysbiosis
Th17 Cells
8 Citations (Scopus)

Nucleotides function as endogenous chemical sensors for oxidative stress signaling

Ihara, H., Sawa, T., Nakabeppu, Y. & Akaike, T., Jan 1 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 33-39 7 p.

Research output: Contribution to journalReview article

Oxidative stress
Chemical sensors
Oxidative Stress
Nucleotides
Nitrogen Oxides
9 Citations (Scopus)

Therapeutic effects of hydrogen in animal models of Parkinson's disease

Fujita, K., Nakabeppu, Y. & Noda, M., Sep 19 2011, In : Parkinson's Disease. 307875.

Research output: Contribution to journalReview article

Therapeutic Uses
Parkinson Disease
Hydrogen
Animal Models
Oxidopamine
2010
8 Citations (Scopus)

A comprehensive screening system for damaged nucleotide-binding proteins

Tsuchimoto, D., Iyama, T., Nonaka, M., Abolhassani, N., Ohta, E., Kunihiko, S. & Nakabeppu, Y., Nov 28 2010, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 703, 1, p. 37-42 6 p.

Research output: Contribution to journalReview article

Inosine Triphosphate
Carrier Proteins
Nucleotides
Inosine Monophosphate
Adenosine Triphosphate
25 Citations (Scopus)

Emerging roles of prostanoids in T cell-mediated immunity

Sakata, D., Yao, C. & Narumiya, S., Aug 1 2010, In : IUBMB Life. 62, 8, p. 591-596 6 p.

Research output: Contribution to journalReview article

T-cells
Cellular Immunity
Prostaglandins
T-Lymphocytes
Immune System Diseases