Research Output 1979 2019

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Review article
2019

Genomic Imprinting and Physiological Processes in Mammals

the Erice Imprinting Group, Feb 21 2019, In : Cell. 176, 5, p. 952-965 14 p.

Research output: Contribution to journalReview article

Physiological Phenomena
Genomic Imprinting
Mammals
Physiology
Genes
2018
2 Citations (Scopus)

Brief summary of the current protocols for generating intestinal organoids

Miura, S. & Suzuki, A., Aug 1 2018, In : Development Growth and Differentiation. 60, 6, p. 387-392 6 p.

Research output: Contribution to journalReview article

Organoids
Intestinal Diseases
Epithelial Cells
Intestines
Food
25 Citations (Scopus)
Interleukin Receptors
Interleukins
Atopic Dermatitis
Pruritus
Skin
2 Citations (Scopus)

The promise of targeted proteomics for quantitative network biology

Matsumoto, M. & Nakayama, K., Dec 1 2018, In : Current Opinion in Biotechnology. 54, p. 88-97 10 p.

Research output: Contribution to journalReview article

Proteomics
Proteins
Assays
Biological Phenomena
Recombinant proteins
6 Citations (Scopus)
Carrier Proteins
Binding Sites
Ligands
Biological Phenomena
Amino Acid Motifs
2017
1 Citation (Scopus)

Cell fate modification toward the hepatic lineage by extrinsic factors

Kawamata, M. & Suzuki, A., Jul 1 2017, In : Journal of Biochemistry. 162, 1, p. 11-16 6 p.

Research output: Contribution to journalReview article

Stem cells
Liver
Hepatocytes
Induced Pluripotent Stem Cells
Fibroblasts
5 Citations (Scopus)

C-type lectin receptors in anti-fungal immunity

Shiokawa, M., Yamasaki, S. & Saijo, S., Dec 1 2017, In : Current Opinion in Microbiology. 40, p. 123-130 8 p.

Research output: Contribution to journalReview article

C-Type Lectins
Immunity
Immune System
Ligands
Mycoses
5 Citations (Scopus)

Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway

Nishio, M., Maehama, T., Goto, H., Nakatani, K., Kato, W., Omori, H., Miyachi, Y., Togashi, H., Shimono, Y. & Suzuki, A., Jan 1 2017, In : Genes to Cells. 22, 1, p. 6-31 26 p.

Research output: Contribution to journalReview article

Cell Polarity
Crowding
Extracellular Matrix
Neoplasms
Carcinogenesis
12 Citations (Scopus)

MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?

Nakabeppu, Y., Ohta, E. & Abolhassani, N., Jun 1 2017, In : Free Radical Biology and Medicine. 107, p. 151-158 8 p.

Research output: Contribution to journalReview article

Nucleotides
Genes
Genome
Knockout Mice
DNA Glycosylases
24 Citations (Scopus)

Recognition of Mycobacterial Lipids by Immune Receptors

Ishikawa, E., Mori, D. & Yamasaki, S., Jan 1 2017, In : Trends in Immunology. 38, 1, p. 66-76 11 p.

Research output: Contribution to journalReview article

Mycobacterium
Glycolipids
Lipids
Immunoreceptor Tyrosine-Based Activation Motif
C-Type Lectins
3 Citations (Scopus)

Temporal regulation of chromatin during myoblast differentiation

Harada, A., Ohkawa, Y. & Imbalzano, A. N., Dec 1 2017, In : Seminars in Cell and Developmental Biology. 72, p. 77-86 10 p.

Research output: Contribution to journalReview article

Myoblasts
Chromatin
Transcription Factors
Histones
Genes

The role of serine/threonine kinase, protein kinase D, in thymocyte development

Ishikawa, E. & Yamasaki, S., Jan 1 2017, In : Seikagaku. 89, 5, p. 748-751 4 p.

Research output: Contribution to journalReview article

Protein-Serine-Threonine Kinases
Thymocytes
protein kinase D
2016
9 Citations (Scopus)

Analysis of cellular signal transduction from an information theoretic approach

Uda, S. & Kuroda, S., Mar 1 2016, In : Seminars in Cell and Developmental Biology. 51, p. 24-31 8 p.

Research output: Contribution to journalReview article

Signal Transduction
Information Theory
Cell Differentiation
Cell Death
Cell Proliferation

Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

Takaku, S., Niimi, N., Kadoya, T., Yako, H., Tsukamoto, M., Sakumi, K., Nakabeppu, Y., Horie, H. & Sango, K., Jun 5 2016, In : AIMS Molecular Science. 3, 3, p. 325-337 13 p.

Research output: Contribution to journalReview article

Open Access
19 Citations (Scopus)

Kawasaki disease: a matter of innate immunity

Hara, T., Nakashima, Y., Sakai, Y., Nishio, H., Motomura, Y. & Yamasaki, S., Nov 1 2016, In : Clinical and Experimental Immunology. 186, 2, p. 134-143 10 p.

Research output: Contribution to journalReview article

Mucocutaneous Lymph Node Syndrome
Innate Immunity
Vasculitis
Nursery Schools
Inflammasomes
9 Citations (Scopus)

The pleiotropic role of non-coding genes in development and cancer

Pasut, A., Matsumoto, A., Clohessy, J. G. & Pandolfi, P. P., Dec 1 2016, In : Current Opinion in Cell Biology. 43, p. 104-113 10 p.

Research output: Contribution to journalReview article

Untranslated RNA
Genes
Neoplasms
Biological Phenomena
Eukaryota
24 Citations (Scopus)

To wake up cancer stem cells, or to let them sleep, that is the question

Takeishi, S. & Nakayama, K., Jul 1 2016, In : Cancer Science. 107, 7, p. 875-881 7 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Sleep
Cell Cycle
Stem Cell Niche
Therapeutics
57 Citations (Scopus)

Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple 'Omic' Layers

Yugi, K., Kubota, H., Hatano, A. & Kuroda, S., Apr 1 2016, In : Trends in Biotechnology. 34, 4, p. 276-290 15 p.

Research output: Contribution to journalReview article

Data integration
Metabolism
Life Style
Technology
Phenotype
2015
6 Citations (Scopus)
Hepatocytes
Liver
Cell Tracking
Cell Lineage
Tamoxifen
4 Citations (Scopus)

MBSJ MCC young scientist award 2012 liver regeneration: A unique and flexible reaction depending on the type of injury

Suzuki, A., Jan 1 2015, In : Genes to Cells. 20, 2, p. 77-84 8 p.

Research output: Contribution to journalReview article

Liver Regeneration
Liver
Wounds and Injuries
Hepatocytes
Living Donors
2014

[Mitochondrial quality control and regulation of neuronal function].

Shirane, M., 2014, In : Seikagaku. The Journal of Japanese Biochemical Society. 86, 4, p. 479-482 4 p.

Research output: Contribution to journalReview article

Biological Transport
Tacrolimus Binding Proteins
Molecular Chaperones
Quality Control
Mitochondria
68 Citations (Scopus)
nucleotides
DNA Glycosylases
Nucleotides
Cell Survival
Carcinogenesis
31 Citations (Scopus)

Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells.

Takeishi, S. & Nakayama, K., Jan 1 2014, In : British journal of cancer. 111, 6, p. 1054-1059 6 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Maintenance
Cell Cycle
Stem Cells
Neoplasms
18 Citations (Scopus)

Specific and quantitative labeling of biomolecules using click chemistry

Horisawa, K., Jan 1 2014, In : Frontiers in Physiology. 5, Nov, 457.

Research output: Contribution to journalReview article

Click Chemistry
Proteins
Systems Biology
Cross Reactions
Cycloaddition Reaction
2013
5 Citations (Scopus)

Artificial induction and disease-related conversion of the hepatic fate

Suzuki, A., Oct 1 2013, In : Current Opinion in Genetics and Development. 23, 5, p. 579-584 6 p.

Research output: Contribution to journalReview article

Hepatocytes
Liver
Liver Diseases
Transcription Factors
Tissue Transplantation
35 Citations (Scopus)

Immune regulatory functions of DOCK family proteins in health and disease

Nishikimi, A., Kukimoto-Niino, M., Yokoyama, S. & Fukui, Y., Sep 10 2013, In : Experimental Cell Research. 319, 15, p. 2343-2349 7 p.

Research output: Contribution to journalReview article

Guanine Nucleotide Exchange Factors
Health
Proteins
PDZ Domains
rho GTP-Binding Proteins
3 Citations (Scopus)

Integrated view of the human chromosome x-centric proteome project

Yamamoto, T., Nakayama, K., Hirano, H., Tomonaga, T., Ishihama, Y., Yamada, T., Kondo, T., Kodera, Y., Sato, Y., Araki, N., Mamitsuka, H. & Goshima, N., Jan 4 2013, In : Journal of Proteome Research. 12, 1, p. 58-61 4 p.

Research output: Contribution to journalReview article

Human Chromosomes
X Chromosome
Proteome
Chromosomes
Antibodies
38 Citations (Scopus)

Nemo-like kinase, a multifaceted cell signaling regulator

Ishitani, T. & Ishitani, S., Jan 1 2013, In : Cellular Signalling. 25, 1, p. 190-197 8 p.

Research output: Contribution to journalReview article

Phosphotransferases
Catenins
Activins
Wnt Signaling Pathway
Mitogen-Activated Protein Kinase Kinases
15 Citations (Scopus)

Regulation of organogenesis and stem cell properties by T-box transcription factors

Takashima, Y. & Suzuki, A., Oct 1 2013, In : Cellular and Molecular Life Sciences. 70, 20, p. 3929-3945 17 p.

Research output: Contribution to journalReview article

Organogenesis
Transcription Factors
Stem Cells
Induced Pluripotent Stem Cells
Regenerative Medicine
19 Citations (Scopus)

Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells

Matsumoto, A. & Nakayama, K., Feb 1 2013, In : Biochimica et Biophysica Acta - General Subjects. 1830, 2, p. 2335-2344 10 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Stem cells
Cell Cycle
Cells
Maintenance
2012
12 Citations (Scopus)

Close link between development and function of gamma-delta T cells

Shibata, K., Apr 1 2012, In : Microbiology and Immunology. 56, 4, p. 217-227 11 p.

Research output: Contribution to journalReview article

Somatostatin-Secreting Cells
T-Lymphocytes
Thymus Gland
Interleukin-17
T-Lymphocyte Subsets
1 Citation (Scopus)

Comprehensive study of protein ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M. & Nakayama, K., Dec 1 2012, In : Seikagaku. 84, 6, p. 479-487 9 p.

Research output: Contribution to journalReview article

Ubiquitination
Ubiquitin
Lysine
Proteins
56 Citations (Scopus)

Genomic imprinting and its relevance to congenital disease, infertility, molar pregnancy and induced pluripotent stem cell

Tomizawa, S. I. & Sasaki, H., Feb 1 2012, In : Journal of Human Genetics. 57, 2, p. 84-91 8 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Hydatidiform Mole
Induced Pluripotent Stem Cells
Infertility
Maintenance
1 Citation (Scopus)
Hepatocyte Nuclear Factor 3-gamma
Hepatocyte Nuclear Factor 3-alpha
Hepatocyte Nuclear Factor 6
Hepatocyte Nuclear Factor 3-beta
Tumor Suppressor Proteins
23 Citations (Scopus)

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

Mori, T., Ikeda, D. D., Yamaguchi, Y. & Unoki, M., Jun 4 2012, In : FEBS Letters. 586, 11, p. 1570-1583 14 p.

Research output: Contribution to journalReview article

Epigenomics
Cell Cycle
Cells
Ubiquitin
Tumors
3 Citations (Scopus)

Protein kinase NLK, that fine-tunes the activity of multiple intracellular signaling pathways

Ishitani, T., 2012, In : Seikagaku. The Journal of Japanese Biochemical Society. 84, 1, p. 39-42 4 p.

Research output: Contribution to journalReview article

Intracellular Signaling Peptides and Proteins
Lithium Chloride
Signal transduction
Phosphorylation
Protein-Serine-Threonine Kinases

The mechanism controlling leukocyte trafficking for acquired immune responses

Fukui, Y., Dec 1 2012, In : Seikagaku. 84, 3, p. 189-194 6 p.

Research output: Contribution to journalReview article

rap1 GTP-Binding Proteins
cdc42 GTP-Binding Protein
rac GTP-Binding Proteins
rho GTP-Binding Proteins
Chemokine Receptors
28 Citations (Scopus)
Neurodegenerative diseases
Neurodegenerative Diseases
Oxidation-Reduction
Antioxidants
Gases
2011

[Studies of T cells for better understanding of immunity and allergy].

Yoshikai, Y., Jan 1 2011, In : Nihon Jibiinkoka Gakkai kaiho. 114, 6, p. 539-546 8 p.

Research output: Contribution to journalReview article

Immunity
Hypersensitivity
T-Lymphocytes
37 Citations (Scopus)

DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis

Oka, S. & Nakabeppu, Y., Apr 1 2011, In : Cancer Science. 102, 4, p. 677-682 6 p.

Research output: Contribution to journalReview article

DNA Glycosylases
Carcinogenesis
Oxidative Stress
Cell Death
DNA
74 Citations (Scopus)

Genomic imprinting in mammals: Its life cycle, molecular mechanisms and reprogramming

Li, Y. & Sasaki, H., Mar 1 2011, In : Cell Research. 21, 3, p. 466-473 8 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Life Cycle Stages
Epigenomics
Mammals
Gametogenesis
8 Citations (Scopus)

Nucleotides function as endogenous chemical sensors for oxidative stress signaling

Ihara, H., Sawa, T., Nakabeppu, Y. & Akaike, T., Jan 1 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 33-39 7 p.

Research output: Contribution to journalReview article

Oxidative stress
Chemical sensors
Oxidative Stress
Nucleotides
Nitrogen Oxides
9 Citations (Scopus)

Therapeutic effects of hydrogen in animal models of Parkinson's disease

Fujita, K., Nakabeppu, Y. & Noda, M., Sep 19 2011, In : Parkinson's Disease. 307875.

Research output: Contribution to journalReview article

Therapeutic Uses
Parkinson Disease
Hydrogen
Animal Models
Oxidopamine
2010
8 Citations (Scopus)

A comprehensive screening system for damaged nucleotide-binding proteins

Tsuchimoto, D., Iyama, T., Nonaka, M., Abolhassani, N., Ohta, E., Kunihiko, S. & Nakabeppu, Y., Nov 28 2010, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 703, 1, p. 37-42 6 p.

Research output: Contribution to journalReview article

Inosine Triphosphate
Carrier Proteins
Nucleotides
Inosine Monophosphate
Adenosine Triphosphate
26 Citations (Scopus)

ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells

Kunihiko, S., Abolhassani, N., Behmanesh, M., Iyama, T., Tsuchimoto, D. & Nakabeppu, Y., Nov 28 2010, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 703, 1, p. 43-50 8 p.

Research output: Contribution to journalReview article

Inosine Triphosphate
Purine Nucleosides
Enzymes
Proteins
Embryonic Structures
46 Citations (Scopus)
Nucleoside-Triphosphatase
Purine Nucleosides
Cell Aging
Mutagenesis
Cell Death
32 Citations (Scopus)

Self and nonself recognition through C-type lectin receptor, Mincle

Miyake, Y., Ishikawa, E., Ishikawa, T. & Yamasaki, S., Oct 1 2010, In : Self/Nonself - Immune Recognition and Signaling. 1, 4, p. 310-313 4 p.

Research output: Contribution to journalReview article

C-Type Lectins
Ligands
Mycobacterium
Fungi
Yeasts
32 Citations (Scopus)

Stalled replication forks: Making ends meet for recognition and stabilization

Masai, H., Tanaka, T. & Kohda, D., Aug 2010, In : BioEssays. 32, 8, p. 687-697 11 p.

Research output: Contribution to journalReview article

Stabilization
DNA Helicases
Null Lymphocytes
Genomic Instability
DNA
2009
101 Citations (Scopus)

Calcium signaling in the development and function of T-lineage cells

Ohora, M., Sep 1 2009, In : Immunological Reviews. 231, 1, p. 210-224 15 p.

Research output: Contribution to journalReview article

Calcium Signaling
NFATC Transcription Factors
Calcineurin
Cell Lineage
Lymphocytes
8 Citations (Scopus)

Functional similarities and uniqueness of p27 and p57: Insight from a knock-in mouse model

Susaki, E. & Nakayama, K., Aug 15 2009, In : Cell Cycle. 8, 16, p. 2497-2501 5 p.

Research output: Contribution to journalReview article

Cyclin-Dependent Kinases
Cyclin-Dependent Kinase Inhibitor p57
Cyclin-Dependent Kinase Inhibitor p27
Genes
Phenotype