Research Output 1979 2020

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Review article
2005
3 Citations (Scopus)

The degradation of p27 and cancer

Kotoshiba, S. & Nakayama, K., Jan 1 2005, In : Nippon rinsho. Japanese journal of clinical medicine. 63, 11, p. 2047-2056 10 p.

Research output: Contribution to journalReview article

Cyclin-Dependent Kinases
Cell Cycle
Cell Cycle Resting Phase
Cyclins
Ubiquitination
2004

Genome database

Suyama, M., Aug 2004, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 49, 11 Suppl, p. 1841-1846 6 p.

Research output: Contribution to journalReview article

Genetic Databases
Internet
Genome
Databases
5 Citations (Scopus)
Immunophilins
Mitochondria
Apoptosis
Tacrolimus Binding Protein 1A
Apoptosis Regulatory Proteins
75 Citations (Scopus)
Mutagenesis
Cell death
Nucleic Acids
DNA Glycosylases
Cell Death
2003

Deregulated Proteolysis of the Cell Cycle Regulator p27Kip1 and Cancers

Susaki, E. & Nakayama, K., Nov 2003, In : Biotherapy. 17, 6, p. 546-555 10 p.

Research output: Contribution to journalReview article

Proteolysis
Cell Cycle
Neoplasms
Ubiquitin
S-Phase Kinase-Associated Proteins
6 Citations (Scopus)

Glutamate receptor genes as candidates for schizophrenia susceptibility

Fukumaki, Y. & Shibata, H., Oct 1 2003, In : Drug Development Research. 60, 2, p. 137-151 15 p.

Research output: Contribution to journalReview article

Glutamate Receptors
Schizophrenia
Genes
Endophenotypes
Haplotypes
217 Citations (Scopus)

Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis

Shirane, M. & Nakayama, K., Jan 1 2003, In : Nature Cell Biology. 5, 1, p. 28-37 10 p.

Research output: Contribution to journalReview article

Tacrolimus Binding Proteins
Mitochondria
Apoptosis
Tacrolimus Binding Protein 1A
Calcineurin
21 Citations (Scopus)

NKT cells are dispensable in the induction of oral tolerance but are indispensable in the abrogation of oral tolerance by prostaglandin E

Ishimitsu, R., Yajima, T., Nishimura, H., Kawauchi, H. & Yoshikai, Y., Jan 1 2003, In : European Journal of Immunology. 33, 1, p. 183-193 11 p.

Research output: Contribution to journalReview article

Prostaglandins E
Alprostadil
Interleukin-4
T-Lymphocytes
Th1-Th2 Balance
33 Citations (Scopus)

Thymic generation and selection of CD25+CD4+ regulatory T cells: Implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance

Sakaguchi, S., Hori, S., Fukui, Y., Sasazuki, T., Sakaguchi, N., Takahashi, T. & Bach, Dec 1 2003, In : Novartis Foundation symposium. 252, p. 6-23 18 p.

Research output: Contribution to journalReview article

Self Tolerance
Regulatory T-Lymphocytes
Thymus Gland
T-Lymphocytes
Ligands
43 Citations (Scopus)

Ubiquitylation as a quality control system for intracellular proteins

Hatakeyama, S. & Nakayama, K. I., Jul 1 2003, In : Journal of biochemistry. 134, 1, p. 1-8 8 p.

Research output: Contribution to journalReview article

Ubiquitination
Quality Control
Quality control
Control systems
Ubiquitin
149 Citations (Scopus)

U-box proteins as a new family of ubiquitin ligases

Hatakeyama, S. & Nakayama, K., Mar 21 2003, In : Biochemical and Biophysical Research Communications. 302, 4, p. 635-645 11 p.

Research output: Contribution to journalReview article

Ligases
Ubiquitin
Fungal Proteins
Fingers
Proteins
2002

A critical role of the CDM family molecule DOCK2 in lymphocyte migration

Fukui, Y., Jan 1 2002, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 47, 16 Suppl, p. 2194-2199 6 p.

Research output: Contribution to journalReview article

rac1 GTP-Binding Protein
rac GTP-Binding Proteins
GTPase-Activating Proteins
Cytoskeleton
Cell Movement

From the structure to the function of the PX domain

Kohda, D., Jan 1 2002, In : Seikagaku. The Journal of Japanese Biochemical Society. 74, 10, p. 1244-1250 7 p.

Research output: Contribution to journalReview article

Secondary Protein Structure
Homeodomain Proteins
Phosphatidylinositol Phosphates
Protein Conformation
src Homology Domains
99 Citations (Scopus)

Functions of outer membrane receptors in mitochondrial protein import

Endo, T. & Kohda, D., Sep 2 2002, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1592, 1, p. 3-14 12 p.

Research output: Contribution to journalReview article

Protein Precursors
Mitochondrial Proteins
Membranes
Mitochondria
Mitochondrial Membranes

Genomic imprinting, X chromosome inactivation and DNA methylation

Sasaki, H., Jan 1 2002, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 47, 13, p. 1822-1828 7 p.

Research output: Contribution to journalReview article

Genomic Imprinting
X Chromosome Inactivation
X Chromosome
DNA Methylation
Tissue Engineering
96 Citations (Scopus)

Roles for the two-hybrid system in exploration of the yeast protein interactome.

Ito, T., Ota, K., Kubota, H., Yamaguchi, Y., Chiba, T., Sakuraba, K. & Yoshida, M., Aug 2002, In : Molecular & cellular proteomics : MCP. 1, 8, p. 561-566 6 p.

Research output: Contribution to journalReview article

Fungal Proteins
Hybrid systems
Two-Hybrid System Techniques
Proteins
Yeast
20 Citations (Scopus)

The postsynaptic density and dendritic raft localization of PSD-Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs

Konno, D., Ko, J. A., Usui, S., Hori, K., Maruoka, H., Inui, M., Fujikado, T., Tano, Y., Suzuki, T., Tohyama, K. & Sobue, K., Dec 1 2002, In : Journal of Cell Science. 115, 23, p. 4695-4706 12 p.

Research output: Contribution to journalReview article

Post-Synaptic Density
Leucine Zippers
Membranes
Cell Membrane
Synaptic Membranes
2001

Coordinated domain-domain interactions in the production of superoxide

Kohda, D., Sumimoto, H. & Inagaki, F., Jan 1 2001, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 46, 11 Suppl, p. 1726-1731 6 p.

Research output: Contribution to journalReview article

Amino Acid Motifs
NADPH Oxidase
Phosphoproteins
Phagocytes
Tertiary Protein Structure
94 Citations (Scopus)

Molecular genetics and structural biology of human MutT homolog, MTH1

Nakabeppu, Y., Jun 2 2001, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 477, 1-2, p. 59-70 12 p.

Research output: Contribution to journalReview article

Single Nucleotide Polymorphism
Molecular Biology
Exons
Messenger RNA
Nucleoside-Triphosphatase
189 Citations (Scopus)

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1

Nakayama, K., Hatakeyama, S. & Nakayama, K., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 282, 4, p. 853-860 8 p.

Research output: Contribution to journalReview article

Proteolysis
Cyclin E
Cell Cycle
Cells
Ubiquitin
44 Citations (Scopus)

Roles of prostaglandins and leukotrienes in acute inflammation caused by bacterial infection

Yoshikai, Y., Jan 1 2001, In : Current Opinion in Infectious Diseases. 14, 3, p. 257-263 7 p.

Research output: Contribution to journalReview article

Leukotrienes
Bacterial Infections
Prostaglandins
Inflammation
Arachidonate 5-Lipoxygenase
2000
79 Citations (Scopus)

Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long- distance gene regulation

Sasaki, H., Ishihara, K. & Kato, R., Jan 1 2000, In : Journal of biochemistry. 127, 5, p. 711-715 5 p.

Research output: Contribution to journalReview article

DNA Methylation
Chromosomes
Gene expression
Chromatin
Genes
38 Citations (Scopus)

The role of interleukin 15 in mounting an immune response against microbial infections

Yoshikai, Y. & Nishimura, H., Jan 1 2000, In : Microbes and Infection. 2, 4, p. 381-389 9 p.

Research output: Contribution to journalReview article

Interleukin-15
Infection
Cytokines
T-Lymphocytes
Adaptive Immunity
1999
45 Citations (Scopus)

The interaction of intestinal epithelial cells and intraepithelial lymphocytes in host defense

Yoshikai, Y., Dec 1 1999, In : Immunologic Research. 20, 3, p. 219-235 17 p.

Research output: Contribution to journalReview article

Epithelial Cells
Lymphocytes
T-Lymphocytes
Listeria monocytogenes
T-Cell Antigen Receptor
1998
169 Citations (Scopus)

Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development

Nakayama, K. & Nakayama, K., Jan 1 1998, In : BioEssays. 20, 12, p. 1020-1029 10 p.

Research output: Contribution to journalReview article

Cyclin-Dependent Kinases
Brakes
Cell Cycle
Cells
Engines

Genomic imprinting and functional chromosome domain

Sasaki, H., Jan 1 1998, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 43, 14, p. 2101-2108 8 p.

Research output: Contribution to journalReview article

Angelman Syndrome
Genomic Imprinting
Prader-Willi Syndrome
Histone Deacetylases
Gene Expression Regulation

Genomic imprinting and mammalian development

Hatano, N. & Sasaki, H., Jan 1 1998, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 43, 4, p. 541-548 8 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Mammals
Alleles
4 Citations (Scopus)

The roles of heat shock proteins in host defense against bacterial infection

Yoshikai, Y., Jan 1 1998, In : Rinsho byori. The Japanese journal of clinical pathology. 46, 6, p. 564-573 10 p.

Research output: Contribution to journalReview article

Cytoprotection
Heat-Shock Proteins
Bacterial Infections
Inflammation
Bacteria
1996
46 Citations (Scopus)

DNA-repair methyltransferase as a molecular device for preventing mutation and cancer

Sekiguchi, M., Nakabeppu, Y., Kunihiko, S. & Tuzuki, T., Jan 1 1996, In : Journal of Cancer Research and Clinical Oncology. 122, 4, p. 199-206 8 p.

Research output: Contribution to journalReview article

Methyltransferases
DNA Repair
Equipment and Supplies
Mutation
DNA
48 Citations (Scopus)

Genomic imprinting: Significance in development and diseases and the molecular mechanisms

Nakao, M. & Sasaki, H., Jan 1 1996, In : Journal of Biochemistry. 120, 3, p. 467-473 7 p.

Research output: Contribution to journalReview article

Genomic Imprinting
Genes
Epigenomics
Angelman Syndrome
Mammalian Embryo
1995

Suppression of experimental autoimmune encephalomyelitis with antibodies against adhesion molecules

Kawai, K., Kobayashi, Y., Miyasaka, M., Yoshikai, Y. & Sobue, G., Dec 1 1995, In : Rinshō shinkeigaku = Clinical neurology. 35, 12, 1 p.

Research output: Contribution to journalReview article

Animal Disease Models
Autoimmune Experimental Encephalomyelitis
Cell Adhesion Molecules
Antibodies
1994

The involvement of gamma delta T cells in neurological disorders

Hiromatsu, K., Kobayashi, Y. & Yoshikai, Y., Jan 1 1994, In : Nippon rinsho. Japanese journal of clinical medicine. 52, 11, p. 2824-2829 6 p.

Research output: Contribution to journalReview article

Somatostatin-Secreting Cells
Nervous System Diseases
T-Lymphocytes
Autoimmune Diseases
Polymyositis
1 Citation (Scopus)

The roles of Hsp in inflammation

Yoshikai, Y., Jan 1 1994, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 39, 5, p. 837-845 9 p.

Research output: Contribution to journalReview article

Heat-Shock Proteins
Reactive Oxygen Species
Homeostasis
B-Lymphocytes
Cytokines
1993
17 Citations (Scopus)

The inheritance of germline-specific epigenetic modifications during development.

Surani, M. A., Sasaki, H., Ferguson-Smith, A. C., Allen, N. D., Barton, S. C., Jones, P. A. & Reik, W., Jan 1 1993, In : Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 339, 1288, p. 165-172 8 p.

Research output: Contribution to journalReview article

Epigenomics
epigenetics
inheritance (genetics)
germ cells
Genes

Viral superantigens

Yoshikai, Y., Jan 1 1993, In : Uirusu. Journal of virology. 43, 1, p. 119-127 9 p.

Research output: Contribution to journalReview article

Molecular Sequence Data
Superantigens
Viral Proteins
Antigen-Presenting Cells
Major Histocompatibility Complex
1992

Regulatory role of heat shock protein-specific T cells in host defense.

Yoshikai, Y., Jan 1 1992, In : Nagoya journal of medical science. 54, 1-4, p. 11-26 16 p.

Research output: Contribution to journalReview article

Heat-Shock Proteins
T-Lymphocytes
Somatostatin-Secreting Cells
Infection
Antigen Receptors, T-Cell, gamma-delta
1989
26 Citations (Scopus)

Human transthyretin (prealbumin) gene and molecular genetics of familial amyloidotic polyneuropthy

Sakaki, Y., Yoshioka, K., Tanahashi, H., Furuya, H. & Sasaki, H., Dec 1 1989, In : Molecular Biology and Medicine. 6, 2, p. 161-168 8 p.

Research output: Contribution to journalReview article

Prealbumin
Amyloidosis
Nervous System Diseases
Molecular Biology
Gene Expression
1988
580 Citations (Scopus)

Regulation and expression of the adaptive response to alkylating agents

Lindahl, T., Sedgwick, B., Sekiguchi, M. & Nakabeppu, Y., Jan 1 1988, In : Annual Review of Biochemistry. 57, p. 133-157 25 p.

Research output: Contribution to journalReview article

Alkylating Agents
Repair
DNA
Mutagens
Proteins