Research Output 1977 2019

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2003
6 Citations (Scopus)

Pepstatin a induces extracellular acidification distinct from aspartic protease inhibition in microglial cell lines

Okada, M., Irie, S., Sawada, M., Urae, R., Urae, A., Iwata, N., Ozaki, N., Akazawa, K. & Nakanishi, H., Aug 1 2003, In : GLIA. 43, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Peptide Hydrolases
Cell Line
Dicyclohexylcarbodiimide
Proton-Translocating ATPases
Protein Kinase C
44 Citations (Scopus)

Potentiation of NMDA receptor-mediated synaptic responses by microglia

Moriguchi, S., Mizoguchi, Y., Tomimatsu, Y., Hayashi, Y., Kadowaki, T., Kagamiishi, Y., Katsube, N., Yamamoto, K., Inoue, K., Watanabe, S., Nabekura, J. & Nakanishi, H., Nov 26 2003, In : Molecular Brain Research. 119, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

Microglia
N-Methyl-D-Aspartate Receptors
N-Methylaspartate
Glutamic Acid
Endopeptidase K
13 Citations (Scopus)

Requirements for distinct steps of phospholipase Cγ2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling

Rodriguez, R., Matsuda, M., Storey, A. & Katan, M., Aug 15 2003, In : Biochemical Journal. 374, 1, p. 269-280 12 p.

Research output: Contribution to journalArticle

Cell signaling
Enzyme Activation
Phospholipases
Hydrolysis
B-Lymphocytes

Search for cerebral G cluster neurons responding to taste stimulation with seaweed in Aplysia kurodai by the use of calcium imaging

Yoshida, R. & Nagahama, T., Jan 1 2003, In : Journal of Neurobiology. 55, 3, p. 299-314 16 p.

Research output: Contribution to journalArticle

Seaweed
Aplysia
Calcium
Neurons
Motor Neurons
6 Citations (Scopus)

The importance to chondrocyte differentiation of changes in expression of the multiple inositol polyphosphate phosphatase

Hidaka, K., Kanematsu, T., Caffrey, J. J., Takeuchi, H., Shears, S. B. & Hirata, M., Nov 1 2003, In : Experimental Cell Research. 290, 2, p. 254-264 11 p.

Research output: Contribution to journalArticle

Chondrocytes
Growth Plate
Inositol
Alkaline Phosphatase
Bone Plates
130 Citations (Scopus)

Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages

Rahman, M., Kukita, A., Kukita, T., Shobuike, T., Nakamura, T. & Kohashi, O., May 1 2003, In : Blood. 101, 9, p. 3451-3459 9 p.

Research output: Contribution to journalArticle

trichostatin A
Histone Deacetylase Inhibitors
Butyric Acid
Macrophages
Osteoclasts
77 Citations (Scopus)

Vanilloid receptor expression in the rat tongue and palate

Kido, M. A., Muroya, H., Yamaza, T., Terada, Y. & Tanaka, T., Jan 1 2003, In : Journal of Dental Research. 82, 5, p. 393-397 5 p.

Research output: Contribution to journalArticle

TRPV Cation Channels
Palate
Tongue
Capsaicin
Pain
2002
50 Citations (Scopus)

Difference in penetration of horseradish peroxidase tracer as a foreign substance into the peri-implant or junctional epithelium of rat gingivae

Ikeda, H., Shiraiwa, M., Yamaza, T., Yoshinari, M., Kido, M. A., Ayukawa, Y., Inoue, T., Koyano, K. & Tanaka, T., Jun 1 2002, In : Clinical Oral Implants Research. 13, 3, p. 243-251 9 p.

Research output: Contribution to journalArticle

Epithelial Attachment
Gingiva
Horseradish Peroxidase
Epithelium
Basement Membrane
5 Citations (Scopus)

Distribution of inducible nitric oxide synthase, interleukin-1β, and interleukin-1 receptor in the temporomandibular joint of normal rats

Masuda, K. F., Yamaza, T., Tsukiyama, Y., Murakami, R., Nishijima, K., Kido, M. A., Koyano, K. & Tanaka, T., May 14 2002, In : Acta Histochemica et Cytochemica. 35, 1, p. 11-21 11 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptors
Synovial Membrane
Temporomandibular Joint
Nitric Oxide Synthase Type II
Interleukin-1
27 Citations (Scopus)

Enhancement of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials in the neostriatum after methamphetamine sensitization: An in vitro slice study

Moriguchi, S., Watanabe, S., Kita, H. & Nakanishi, H., May 20 2002, In : Experimental Brain Research. 144, 2, p. 238-246 9 p.

Research output: Contribution to journalArticle

Neostriatum
Methamphetamine
Excitatory Postsynaptic Potentials
N-Methyl-D-Aspartate Receptors
Cyclic AMP-Dependent Protein Kinases
40 Citations (Scopus)

Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells

Sakai, H., Jingushi, S., Shuto, T., Urabe, K., Ikenoue, T., Okazaki, K., Kukita, T., Kukita, A. & Iwamoto, Y., Jan 1 2002, In : Annals of the Rheumatic Diseases. 61, 2, p. 103-109 7 p.

Research output: Contribution to journalArticle

Arthroplasty
Granulation
Granulation Tissue
Osteoclasts
Fibroblasts
80 Citations (Scopus)

Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia

Nishioku, T., Hashimoto, K., Yamashita, K., Liou, S. Y., Kagamiishi, Y., Maegawa, H., Katsube, N., Peters, C., Von Figura, K., Saftig, P., Katunuma, N., Yamamoto, K. & Nakanishi, H., Feb 15 2002, In : Journal of Biological Chemistry. 277, 7, p. 4816-4822 7 p.

Research output: Contribution to journalArticle

Cathepsin E
Antigen Presentation
Microglia
Antigens
Processing
31 Citations (Scopus)
Osteophyte
Experimental Arthritis
Ankle Joint
Calcitonin Gene-Related Peptide
Synovial Fluid
1 Citation (Scopus)

Ion channels and second messengers involved in transduction and modulation of sweet taste in mouse taste cells

Sugimoto, K., Shigemura, N., Nakano, K., Ohta, R., Nakashima, K., Kawai, K. & Ninomiya, Y., Jul 1 2002, In : Pure and Applied Chemistry. 74, 7, p. 1141-1151 11 p.

Research output: Contribution to journalArticle

Second Messenger Systems
Leptin
Ion Channels
Cells
Depolarization
11 Citations (Scopus)

Letter to the editor: 1H, 13C and 15N resonance assignments of GABARAP, GABAA receptor associated protein [4]

Kouno, T., Miura, K., Kanematsu, T., Shirakawa, M., Hirata, M. & Kawano, K., Feb 28 2002, In : Journal of Biomolecular NMR. 22, 1, p. 97-98 2 p.

Research output: Contribution to journalArticle

Signal Transducing Adaptor Proteins
Nitrogen Isotopes
Carbon Isotopes
Recombinant Fusion Proteins
Microtubule-Associated Proteins
56 Citations (Scopus)

Molecules interacting with PRIP-2, a novel Ins(1,4,5)P3 binding protein type 2: Comparison with PRIP-1

Uji, A., Matsuda, M., Kukita, T., Maeda, K., Kanematsu, T. & Hirata, M., Dec 20 2002, In : Life Sciences. 72, 4-5, p. 443-453 11 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate
Butyric Acid
Carrier Proteins
Amino Acid Receptors
Protein Phosphatase 1
61 Citations (Scopus)

Phospholipase D2 directly interacts with aldolase via its PH domain

Kim, J. H., Lee, S., Kim, J. H., Lee, T. G., Hirata, M., Suh, P. G. & Ryu, S. H., Mar 12 2002, In : Biochemistry. 41, 10, p. 3414-3421 8 p.

Research output: Contribution to journalArticle

Fructose-Bisphosphate Aldolase
Phospholipase D
Metabolites
Glyceraldehyde 3-Phosphate
phospholipase D2
77 Citations (Scopus)

Proteases involved in long-term potentiation

Tomimatsu, Y., Idemoto, S., Moriguchi, S., Watanabe, S. & Nakanishi, H., Dec 20 2002, In : Life Sciences. 72, 4-5, p. 355-361 7 p.

Research output: Contribution to journalArticle

Long-Term Potentiation
Peptide Hydrolases
N-Methyl-D-Aspartate Receptors
Chemical activation
Calpain
107 Citations (Scopus)

Role of the PLC-related, catalytically inactive protein p130 in GABAA receptor function

Kanematsu, T., Jang, I. S., Yamaguchi, T., Nagahama, H., Yoshimura, K., Hidaka, K., Matsuda, M., Takeuchi, H., Misumi, Y., Nakayama, K., Yamamoto, T., Akaike, N., Hirata, M. & Nakayama, K., Mar 1 2002, In : EMBO Journal. 21, 5, p. 1004-1011 8 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Programmable logic controllers
Proteins
Diazepam
gamma-Aminobutyric Acid
2 Citations (Scopus)

The analysis of protein-protein interaction with special reference to PRIP-1

Kanematsu, T. & Hirata, M., May 11 2002, In : Folia Pharmacologica Japonica. 119, 4, p. 241-246 6 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
GABA-A Receptors
Proteins
Galactosidases
EF Hand Motifs
24 Citations (Scopus)

The role of MDM2 in the proliferative activity of ameloblastoma

Sandra, F., Nakamura, N., Kanematsu, T., Hirata, M. & Ohishi, M., Mar 4 2002, In : Oral Oncology. 38, 2, p. 153-157 5 p.

Research output: Contribution to journalArticle

Ameloblastoma
Proto-Oncogene Proteins c-mdm2
Neoplasms
Western Blotting
Enzyme-Linked Immunosorbent Assay
27 Citations (Scopus)

TNF inhibited the apoptosis by activation of Akt serine/threonine kinase in the human head and neck squamous cell carcinoma

Sandra, F., Matsuki, N. A., Takeuchi, H., Ikebe, T., Kanematsu, T., Ohishi, M. & Hirata, M., Jun 17 2002, In : Cellular Signalling. 14, 9, p. 771-778 8 p.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
Tumor Necrosis Factor-alpha
Apoptosis
Cell Survival
Phosphatidylinositol 3-Kinases
2001

An epidemiologic examination on the prevalence of the periodontal diseases and oral pigmentation in Yusho patients in 2000

Hashiguchi, I., Yamaza, T., Koishi, Y., Goto, Y., Yoshito, Y., Akamine, A., Fukuyama, H. & Okumura, H., Jan 1 2001, In : Fukuoka igaku zasshi = Hukuoka acta medica. 92, 5, p. 115-119 5 p.

Research output: Contribution to journalArticle

Pigmentation
Periodontal Diseases
Periodontal Pocket
Tooth
Polychlorinated Biphenyls
41 Citations (Scopus)

Arg-gingipain is responsible for the degradation of cell adhesion molecules of human gingival fibroblasts and their death induced by Porphyromonas gingivalis

Baba, A., Abe, N., Kadowaki, T., Nakanishi, H., Ohishi, M., Asao, T. & Yamamoto, K., Jul 21 2001, In : Biological chemistry. 382, 5, p. 817-824 8 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Cell Adhesion Molecules
Fibroblasts
Degradation
Fibronectins
10 Citations (Scopus)

Calcium imaging for detection and estimation of spike activities in Aplysia neurons

Yoshida, R., Iwamoto, A. & Nagahama, T., Jul 1 2001, In : Zoological science. 18, 5, p. 631-643 13 p.

Research output: Contribution to journalArticle

neurons
image analysis
calcium
dyes
cells
23 Citations (Scopus)

Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy

Yamaza, T., Tsuji, Y., Goto, T., Kido, M. A., Nishijima, K., Moroi, R., Akamine, A. & Tanaka, T., Jan 1 2001, In : Bone. 29, 1, p. 42-53 12 p.

Research output: Contribution to journalArticle

Cathepsin K
Cystatin C
Epiphyses
Immunoelectron Microscopy
Osteoclasts
30 Citations (Scopus)

Contribution of conformational stability of hen lysozyme to induction of type 2 T-helper immune responses

So, T., Ito, H. O., Hirata, M., Ueda, T. & Imoto, T., Nov 26 2001, In : Immunology. 104, 3, p. 259-268 10 p.

Research output: Contribution to journalArticle

Muramidase
T-Lymphocytes
Interleukin-4
Proteins
Th2 Cells
25 Citations (Scopus)

Detection of differentially expressed genes in the early developmental stage of the mouse mandible

Yamaza, H., Matsuo, K., Kiyoshima, T., Shigemura, N., Kobayashi, I., Wada, H., Akamime, A. & Sakai, H., Aug 2 2001, In : International Journal of Developmental Biology. 45, 4, p. 675-680 6 p.

Research output: Contribution to journalArticle

Mandible
Odontogenesis
Tooth Germ
Genes
Tongue
18 Citations (Scopus)

Expression of cathepsin K mRNA and protein in odontoclasts after experimental tooth movement in the mouse maxilla by in situ hybridization and immunoelectron microscopy

Tsuji, Y., Yamaza, T., Kido, M. A., Goto, T., Nakata, S., Akamine, A., Nakasima, A. & Tanaka, T., Apr 11 2001, In : Cell and tissue research. 303, 3, p. 359-369 11 p.

Research output: Contribution to journalArticle

Cathepsin K
Tooth Movement Techniques
Immunoelectron Microscopy
Maxilla
Osteoclasts
21 Citations (Scopus)

Immunohistochemical localization of osteopontin in human pulp stones

Ninomiya, M., Ohishi, M., Kido, J. I., Ohsaki, Y. & Nagata, T., Jan 1 2001, In : Journal of Endodontics. 27, 4, p. 269-272 4 p.

Research output: Contribution to journalArticle

Dental Pulp Calcification
Osteopontin
Osteonectin
Dental Pulp
Osteocalcin
8 Citations (Scopus)

Inositol-1,4,5-trisphosphate-binding proteins controlling the phototransduction cascade of invertebrate visual cells

Kishigami, A., Ogasawara, T., Watanabe, Y., Hirata, M., Maeda, T., Hayashi, F. & Tsukahara, Y., Mar 10 2001, In : Journal of Experimental Biology. 204, 3, p. 487-493 7 p.

Research output: Contribution to journalArticle

Light Signal Transduction
phototransduction
Inositol 1,4,5-Trisphosphate
Invertebrates
binding proteins
60 Citations (Scopus)

Interaction of p130 with, and Consequent Inhibition of, the Catalytic Subunit of Protein Phosphatase 1α

Yoshimura, K., Takeuchi, H., Sato, O., Hidaka, K., Doira, N., Terunuma, M., Harada, K., Ogawa, Y., Ito, Y., Kanematsu, T. & Hirata, M., Jan 25 2001, In : Journal of Biological Chemistry. 276, 21, p. 17908-17913 6 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
COS Cells
Brain
Inositol 1,4,5-Trisphosphate
Type C Phospholipases
69 Citations (Scopus)

Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity

Miyamoto, K. I., Nakanishi, H., Moriguchi, S., Fukuyama, N., Eto, K., Wakamiya, J., Murao, K., Arimura, K. & Osame, M., May 18 2001, In : Brain Research. 901, 1-2, p. 252-258 7 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Neurons
Occipital Lobe
Peroxynitrous Acid
Dizocilpine Maleate
90 Citations (Scopus)

Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice

Nakanishi, H., Zhang, J., Koike, M., Nishioku, T., Okamoto, Y., Kominami, E., Von Figura, K., Peters, C., Yamamoto, K., Saftig, P. & Uchiyama, Y., Oct 1 2001, In : Journal of Neuroscience. 21, 19, p. 7526-7533 8 p.

Research output: Contribution to journalArticle

Microglia
Nitric Oxide
Nitric Oxide Synthase Type II
Ceroid
Macrophages
41 Citations (Scopus)

Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5

Hidaka, K., Kanematsu, T., Takeuchi, H., Nakata, M., Kikkawa, U. & Hirata, M., Sep 15 2001, In : International Journal of Biochemistry and Cell Biology. 33, 11, p. 1094-1103 10 p.

Research output: Contribution to journalArticle

Embryonal Carcinoma Stem Cells
Chondrogenesis
Proto-Oncogene Proteins c-akt
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
9 Citations (Scopus)
Osteoclasts
Osteogenesis
Calcitonin Receptors
Antigens
Antigen Receptors
26 Citations (Scopus)

Localization of activated caspase-3-positive and apoptotic cells in the developing tooth germ of the mouse lower first molar

Shigemura, N., Kiyoshima, T., Sakai, T., Matsuo, K., Momoi, T., Yamaza, H., Kobayashi, I., Wada, H., Akamine, A. & Sakai, H., Jan 1 2001, In : Histochemical Journal. 33, 5, p. 253-258 6 p.

Research output: Contribution to journalArticle

Tooth Germ
Caspase 3
Morphogenesis
Tooth
Embryonic Structures
10 Citations (Scopus)

Neural stem cells lose telomerase activity upon differentiating into astrocytes

Miura, T., Katakura, Y., Yamamoto, K., Uehara, N., Tsuchiya, T., Kim, E. H. & Shirahata, S., Dec 1 2001, In : Cytotechnology. 36, 1-3, p. 137-144 8 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Telomerase
Stem cells
Astrocytes
Embryonic Structures
7 Citations (Scopus)
Receptor Activator of Nuclear Factor-kappa B
Antigen Receptors
Differentiation Antigens
Calcitonin
Osteoclasts
10 Citations (Scopus)

Substance P activates osteoclast formation and osteoclastic bene resorption through the neurokinin-1 receptor

Goto, T., Yamaza, T., Kido, M. A. & Tanaka, T., Jan 1 2001, In : Acta Histochemica et Cytochemica. 34, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptors
Osteoclasts
Substance P
Bone
Bone Resorption
2 Citations (Scopus)

Subtractive screening of genes involved in cellular senescence

Uehara, N., Katakura, Y., Miura, T. & Shirahata, S., Jan 1 2001, In : Cytotechnology. 35, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

Cell Aging
Screening
Complementary DNA
Genes
Cells
14 Citations (Scopus)

Topography and distribution of sympathetic nerve fibers in the rat temporomandibular joint: Immunocytochemistry and ultrastructure

Kido, M. A., Zhang, J. Q., Muroya, H., Yamaza, T., Terada, Y. & Tanaka, T., 2001, In : Anatomy and Embryology. 203, 5, p. 357-366 10 p.

Research output: Contribution to journalArticle

Adrenergic Fibers
Neuropeptide Y
Temporomandibular Joint
Nerve Fibers
Immunohistochemistry
91 Citations (Scopus)

Tumor necrosis factor-α cooperates with receptor activator of nuclear factor κB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture

Komine, M., Kukita, A., Kukita, T., Ogata, Y., Hotokebuchi, T. & Kohashi, O., May 17 2001, In : Bone. 28, 5, p. 474-483 10 p.

Research output: Contribution to journalArticle

Osteoclasts
Cytoplasmic and Nuclear Receptors
Stromal Cells
Bone Marrow Cells
Cell Culture Techniques
63 Citations (Scopus)

Tyrosine Residues in Phospholipase Cγ2 Essential for the Enzyme Function in B-cell Signaling

Rodriguez, R., Matsuda, M., Perisic, O., Bravo, J., Paul, A., Jones, N. P., Light, Y., Swann, K., Williams, R. L. & Katan, M., Dec 21 2001, In : Journal of Biological Chemistry. 276, 51, p. 47982-47992 11 p.

Research output: Contribution to journalArticle

Cell signaling
Phosphorylation
Phospholipases
Tyrosine
B-Lymphocytes
2000
215 Citations (Scopus)

AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia

Noda, M., Nakanishi, H., Nabekura, J. & Akaike, N., Jan 1 2000, In : Journal of Neuroscience. 20, 1, p. 251-258 8 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Kainic Acid
Glutamate Receptors
Microglia
Kainic Acid Receptors
287 Citations (Scopus)

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

Koike, M., Nakanishi, H., Saftig, P., Ezaki, J., Isahara, K., Ohsawa, Y., Schulz-Schaeffer, W., Watanabe, T., Waguri, S., Kametaka, S., Shibata, M., Yamamoto, K., Kominami, E., Peters, C., Von Figura, K. & Uchiyama, Y., Sep 15 2000, In : Journal of Neuroscience. 20, 18, p. 6898-6906 9 p.

Research output: Contribution to journalArticle

Ceroid
Lipofuscin
Cathepsin D
Neurons
Brain
68 Citations (Scopus)

Cyclosporin A decreases the degradation of type I collagen in rat gingival overgrowth

Kataoka, M., Shimizu, Y., Kunikiyo, K., Asahara, Y., Yamashita, K., Ninomiya, M., Morisaki, I., Ohsaki, Y., Kido, J. I. & Nagata, T., Jan 29 2000, In : Journal of cellular physiology. 182, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Gingival Overgrowth
Collagen Type I
Cyclosporine
Rats
Gingiva
29 Citations (Scopus)

Dietary effects of eicosapentaenoic and docosahexaenoic acid esters on lipid metabolism and immune parameters in sprague-dawley rats

Hung, P., Gu, J., Kaku, S., Yunoki, S. I., Ohkura, K. I., Ikeda, I., Tachibana, H., Sugano, M., Yazawa, K. & Yamada, K., Jan 1 2000, In : Bioscience, Biotechnology and Biochemistry. 64, 12, p. 2588-2593 6 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Docosahexaenoic Acids
Lipid Metabolism
Sprague Dawley Rats
Rats
80 Citations (Scopus)

Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs

Jones, K. T., Matsuda, M., Parrington, J., Katan, M. & Swann, K., Mar 15 2000, In : Biochemical Journal. 346, 3, p. 743-749 7 p.

Research output: Contribution to journalArticle

Tissue Extracts
Sea Urchins
Type C Phospholipases
Eggs
Ovum
54 Citations (Scopus)

Domain organization of p130, PLC-related catalytically inactive protein, and structural basis for the lack of enzyme activity

Kanematsu, T., Yoshimura, K., Hidaka, K., Takeuchi, H., Katan, M. & Hirata, M., May 30 2000, In : European Journal of Biochemistry. 267, 9, p. 2731-2737 7 p.

Research output: Contribution to journalArticle

Enzyme activity
Type C Phospholipases
Programmable logic controllers
Catalyst activity
Enzymes