Oral health, growth and development

Research Output

In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice

Yamaza, T., Alatas, F. S., Yuniartha, R., Yamaza, H., Fujiyoshi, J. K., Yanagi, Y., Yoshimaru, K., Hayashida, M., Matsuura, T., Aijima, R., Ihara, K., Ohga, S., Shi, S., Nonaka, K. & Taguchi, T., Sep 10 2015, In : Stem Cell Research and Therapy. 6, 1, 171.

Research output: Contribution to journalArticle

27 Citations (Scopus)

In vivo impact of a 4 bp deletion mutation in the DLX3 gene on bone development

Choi, S. J., Roodman, G. D., Feng, J. Q., Song, I. S., Amin, K., Hart, P. S., Wright, J. T., Haruyama, N. & Hart, T. C., Jan 1 2009, In : Developmental Biology. 325, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Involvement of Ca2+ in globular adiponectin-induced reactive oxygen species

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N. & Yamashita, Y., Apr 17 2009, In : Biochemical and Biophysical Research Communications. 381, 4, p. 649-653 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species

Fujimoto, A., Akifusa, S., Kamio, N., Hirofuji, T., Nonaka, K. & Yamashita, Y., Jan 25 2010, In : Free Radical Research. 44, 2, p. 128-134 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Involvement of multiple taste receptors in umami taste: Analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice

Yasumatsu, K., Manabe, T., Yoshida, R., Iwatsuki, K., Uneyama, H., Takahashi, I. & Ninomiya, Y., Feb 15 2015, In : Journal of Physiology. 593, 4, p. 1021-1034 14 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Involvement of PRIP, phospholipase C-related, but catalytically inactive protein, in bone formation

Tsutsumi, K., Matsuda, M., Kotani, M., Mizokami, A., Murakami, A., Takahashi, I., Terada, Y., Kanematsu, T., Fukami, K., Takenawa, T., Jimi, E. & Hirata, M., Sep 2 2011, In : Journal of Biological Chemistry. 286, 35, p. 31032-31042 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Involvement of PRIP (Phospholipase C-Related but Catalytically Inactive Protein) in BMP-Induced Smad Signaling in Osteoblast Differentiation

Kotani, M., Matsuda, M., Murakami, A., Takahashi, I., Katagiri, T. & Hirata, M., Dec 1 2015, In : Journal of Cellular Biochemistry. 116, 12, p. 2814-2823 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell

Fujimoto, A., Akifusa, S., Hirofuji, T. & Yamashita, Y., Sep 1 2011, In : Molecular Immunology. 48, 15-16, p. 2052-2058 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Involvement of the JAK-STAT Pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage raw 264 cells

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N., Nonaka, K. & Yamashita, Y., Oct 15 2010, In : Journal of Cellular Biochemistry. 111, 3, p. 597-606 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Involvement of the novel two-component nsrrs and lcrrs systems in distinct resistance pathways against nisin a and nukacin isk-1 in streptococcus mutans

Kawada-Matsuo, M., Oogai, Y., Zendo, T., Nagao, J., Shibata, Y., Yamashita, Y., Ogura, Y., Hayashi, T., Sonomoto, K. & Komatsuzawa, H., Aug 1 2013, In : Applied and environmental microbiology. 79, 15, p. 4751-4755 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Isolation and characterization of a novel poly(vinyl alcohol)-degrading bacterium, Sphingopyxis sp. PVA3

Yamatsu, A., Matsumi, R., Atomi, H. & Imanaka, T., Oct 1 2006, In : Applied Microbiology and Biotechnology. 72, 4, p. 804-811 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Isolation and characterization of the dnaKJ operon from Actinobacillus actinomycetemcomitans

Yoshida, A., Nakano, Y., Yamashita, Y., Yu, H., Ohishi, M. & Koga, T., Dec 1 1997, In : Mitochondrial DNA. 8, 1-2, p. 93-98 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Isolation and characterization of the rml gene homologs from Porphyromonas gingivalis

Shibata, Y., Yamashita, Y., Nakano, Y. & Koga, T., Dec 1999, In : Oral Microbiology and Immunology. 14, 6, p. 339-347 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Isoprenoid biosynthesis in Archaea - Biochemical and evolutionary implications

Matsumi, R., Atomi, H., Driessen, A. J. M. & van der Oost, J., Jan 1 2011, In : Research in Microbiology. 162, 1, p. 39-52 14 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells

Kihara, M., Kiyoshima, T., Nagata, K., Wada, H., Fujiwara, H., Hasegawa, K., Someya, H., Takahashi, I. & Sakai, H., Jul 31 2014, In : PloS one. 9, 7, e103928.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Kinase activity of the dgk gene product is involved in the virulence of Streptococcus mutans

Shibata, Y., van der Ploeg, J. R., Kozuki, T., Shirai, Y., Saito, N., Kawada-Matsuo, M., Takeshita, T. & Yamashita, Y., Apr 27 2009, In : Microbiology. 155, 2, p. 557-565 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Laminin α5 is required for dental epithelium growth and polarity and the development of tooth bud and shape

Fukumoto, S., Miner, J. H., Ida, H., Fukumoto, E., Yuasa, K., Miyazaki, H., Hoffman, M. P. & Yamada, Y., Feb 24 2006, In : Journal of Biological Chemistry. 281, 8, p. 5008-5016 9 p.

Research output: Contribution to journalArticle

Open Access
81 Citations (Scopus)

Large sialolith in the submandibular gland of a child

Konishi, I., Fukumoto, S., Yamada, A., Nonaka, K., Konishi, I. & Fujiwara, T., Jan 1 2005, In : pediatric dental journal. 15, 1, p. 143-146 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Leptin suppresses mouse taste cell responses to sweet compounds

Yoshida, R., Noguchi, K., Shigemura, N., Jyotaki, M., Takahashi, I., Margolskee, R. F. & Ninomiya, Y., Nov 2015, In : Diabetes. 64, 11, p. 3751-3762 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Letter to the Editor, "multiscale analyses of the bone-implant interface"

Albogha, M. H., Dec 1 2015, In : Journal of Dental Research. 94, 12, 1 p.

Research output: Contribution to journalLetter

Lipin-2 degradation elicits a proinflammatory gene signature in macrophages

Watahiki, A., Shimizu, K., Hoshikawa, S., Chiba, M., Kitamura, H., Egusa, H., Fukumoto, S. & Inuzuka, H., Apr 2 2020, In : Biochemical and Biophysical Research Communications. 524, 2, p. 477-483 7 p.

Research output: Contribution to journalArticle

Localization of activated caspase-3-positive and apoptotic cells in the developing tooth germ of the mouse lower first molar

Shigemura, N., Kiyoshima, T., Sakai, T., Matsuo, K., Momoi, T., Yamaza, H., Kobayashi, I., Wada, H., Akamine, A. & Sakai, H., Jan 1 2001, In : Histochemical Journal. 33, 5, p. 253-258 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Long-term oral administration of osteocalcin induces insulin resistance in male mice fed a high-fat, high-sucrose diet

Yasutake, Y., Mizokami, A., Kawakubo-Yasukochi, T., Chishaki, S., Takahashi, I., Takeuchi, H. & Hirata, M., Apr 15 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 310, 8, p. E662-E675

Research output: Contribution to journalArticle

14 Citations (Scopus)

Loop-mediated isothermal amplification method targeting the lytA gene for detection of Streptococcus pneumoniae

Seki, M., Yamashita, Y., Torigoe, H., Tsuda, H., Sato, S. & Maeno, M., Apr 1 2005, In : Journal of Clinical Microbiology. 43, 4, p. 1581-1586 6 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Loss of occlusal support affects the decline in activities of daily living in elderly people receiving home care

Genkai, S., Kikutani, T., Suzuki, R., Tamura, F., Yamashita, Y. & Yoshida, M., Oct 2015, In : Journal of Prosthodontic Research. 59, 4, p. 243-248 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Magnetic attachment for denture type appliance in pediatric patients

Yamada, A., Fukumoto, S., Kamasaki, Y., Kubota, K. & Fujiwara, T., Jan 1 2004, In : pediatric dental journal. 14, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

Maximum principal strain as a criterion for prediction of orthodontic mini-implants failure in subject-specific finite element models

Albogha, M. H., Kitahara, T., Todo, M., Hyakutake, H. & Takahashi, I., Jan 2016, In : Angle Orthodontist. 86, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mechanisms underlying the induction of regulatory T cells by sublingual immunotherapy

Tanaka, Y., Fukumoto, S. & Sugawara, S., Jun 2019, In : journal of oral biosciences. 61, 2, p. 73-77 5 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene

Yoshizaki, K., Hu, L., Nguyen, T., Sakai, K., Ishikawa, M., Takahashi, I., Fukumoto, S., DenBesten, P. K., Bikle, D. D., Oda, Y. & Yamada, Y., Jan 1 2017, In : Journal of Biological Chemistry. 292, 33, p. 13531-13540 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Microbial community in persistent apical periodontitis: A 16S rRNA gene clone library analysis

Zakaria, M. N., Takeshita, T., Shibata, Y., Maeda, H., Wada, N., Akamine, A. & Yamashita, Y., Jan 1 2015, In : International Endodontic Journal. 48, 8, p. 717-728 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Microfloral characterization of the tongue coating and associated risk for pneumonia-related health problems in institutionalized older adults

Takeshita, T., Tomioka, M., Shimazaki, Y., Matsuyama, M., Koyano, K., Matsuda, K. & Yamashita, Y., Jan 1 2010, In : Journal of the American Geriatrics Society. 58, 6, p. 1050-1057 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

MicroRNA-200a regulates the development of mandibular condylar cartilage

Umeda, M., Terao, F., Miyazaki, K., Yoshizaki, K. & Takahashi, I., Jun 5 2015, In : Journal of Dental Research. 94, 6, p. 795-802 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
6 Citations (Scopus)

Mitochondria regulate the differentiation of stem cells from human exfoliated deciduous teeth

Kato, H., Pham, T. T. M., Yamaza, H., Masuda, K., Hirofuji, Y., Han, X., Sato, H., Taguchi, T. & Nonaka, K., Jan 1 2017, In : Cell structure and function. 42, 2, p. 105-116 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using internal transcribed spacer region

Ieda, S., Moriyama, M., Takashita, T., Maehara, T., Imabayashi, Y., Shinozaki, S., Tanaka, A., Hayashida, J. N., Furukawa, S., Ohta, M., Yamashita, Y. & Nakamura, S., Jun 30 2014, In : PloS one. 9, 6, e101156.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using next-generation sequencing

Imabayashi, Y., Moriyama, M., Takeshita, T., Ieda, S., Hayashida, J. N., Tanaka, A., Maehara, T., Furukawa, S., Ohta, M., Kubota, K., Yamauchi, M., Ishiguro, N., Yamashita, Y. & Nakamura, S., Jun 16 2016, In : Scientific reports. 6, 28110.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Molecular and genetic analysis of multiple changes in the levels of production of virulence factors in a subcultured variant of Streptococcus mutans

Yamashita, Y., Tsukioka, Y., Nakano, Y., Shibata, Y. & Koga, T., Oct 15 1996, In : FEMS microbiology letters. 144, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Molecular and immunological characterization of a 64‐kDa protein of Actinobacillus actinomycetemcomitans

Nakano, Y., Inai, Y., Yamashita, Y., Nagaoka, S., Kusuzaki‐Nagira, T., Nishihara, T., Okahashi, N. & Koga, T., Jan 1 1995, In : Oral Microbiology and Immunology. 10, 3, p. 151-159 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Molecular characterization of a gene locus encoding biosynthesis pathway of Streptococcus mutans serotype C-specific antigen

Yamashita, Y., Tsukioka, Y., Oho, T., Nakano, Y. & Koga, T., Oct 23 1997, In : Advances in experimental medicine and biology. 418, p. 1011-1014 4 p.

Research output: Contribution to journalArticle

Molecular characterization of fungal populations on the tongue dorsum of institutionalized elderly adults

Li, H., Takeshita, T., Furuta, M., Tomioka, M., Shibata, Y., Shimazaki, Y., Makimura, K. & Yamashita, Y., Nov 1 2012, In : Oral Diseases. 18, 8, p. 771-777 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Multiple functional involvement of Thymosin beta-4 in tooth germ development

Ookuma, Y. F., Kiyoshima, T., Kobayashi, I., Nagata, K., Wada, H., Fujiwara, H., Yamaza, H., Nonaka, K. & Sakai, H., Feb 1 2013, In : Histochemistry and Cell Biology. 139, 2, p. 355-370 16 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mutant DLX 3 disrupts odontoblast polarization and dentin formation

Choi, S. J., Song, I. S., Feng, J. Q., Gao, T., Haruyama, N., Gautam, P., Robey, P. G. & Hart, T. C., Aug 2010, In : Developmental Biology. 344, 2, p. 682-692 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation

Liu, J., Saito, K., Maruya, Y., Nakamura, T., Yamada, A., Fukumoto, E., Ishikawa, M., Iwamoto, T., Miyazaki, K., Yoshizaki, K., Ge, L. & Fukumoto, S., Mar 31 2016, In : Scientific reports. 6, 23670.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains

Arai, C., Yoshizaki, K., Miyazaki, K., Saito, K., Yamada, A., Han, X., Funada, K., Fukumoto, E., Haruyama, N., Iwamoto, T., Takahashi, I. & Fukumoto, S., Mar 27 2017, In : Scientific reports. 7, 45181.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nerve growth factor (NGF) supports tooth morphogenesis in mouse first branchial arch explants

Amano, O., Bringas, P., Takahashi, I., Takahashi, K., Yamane, A., Chai, Y., Nuckolls, G. H., Shum, L. & Slavkin, H. C., Nov 11 1999, In : Developmental Dynamics. 216, 3, p. 299-310 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Neurodevelopmental outcomes in infants with birth weight ≤500 g at 3 years of age

Inoue, H., Ochiai, M., Sakai, Y., Yasuoka, K., Tanaka, K., Ichiyama, M., Kurata, H., Fujiyoshi, J., Matsushita, Y., Honjo, S., Nonaka, K., Taguchi, T., Kato, K. & Ohga, S., Dec 2018, In : Pediatrics. 142, 6, e20174286.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Neurotrophic factor neurotrophin-4 regulates ameloblastin expression via full-length TrkB

Yoshizaki, K., Yamamoto, S., Yamada, A., Yuasa, K., Iwamoto, T., Fukumoto, E., Harada, H., Saito, M., Nakasima, A., Nonaka, K., Yamada, Y. & Fukumoto, S., Feb 8 2008, In : Journal of Biological Chemistry. 283, 6, p. 3385-3391 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Neurotrophic factor NT-4 regulates ameloblastin expression

Yoshizaki, K., Yamada, A., Yuasa, K., Yamamoto, S., Iwamoto, T., Harada, H., Saito, M., Fukumoto, E., Nonaka, K. & Fukumoto, S., Nov 1 2007, In : European Cells and Materials. 14, SUPPL.2, 1 p.

Research output: Contribution to journalArticle