Oral health, growth and development

Research Output 1984 2020

2015
9 Citations (Scopus)

Serum antibody to Porphyromonas gingivalis and periodontitis progression: The Hisayama Study

Takeuchi, K., Furuta, M., Takeshita, T., Shibata, Y., Shimazaki, Y., Akifusa, S., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., Aug 1 2015, In : Journal of Clinical Periodontology. 42, 8, p. 719-725 7 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Periodontitis
Antibodies
Serum
Logistic Models
36 Citations (Scopus)

The life-extending effect of dietary restriction requires Foxo3 in mice

Shimokawa, I., Komatsu, T., Hayashi, N., Kim, S. E., Kawata, T., Park, S., Hayashi, H., Yamaza, H., Chiba, T. & Mori, R., Aug 1 2015, In : Aging cell. 14, 4, p. 707-709 3 p.

Research output: Contribution to journalArticle

Neoplasms
Forkhead Transcription Factors
23 Citations (Scopus)

Transplantation of mesenchymal stem cells ameliorates secondary osteoporosis through interleukin-17-impaired functions of recipient bone marrow mesenchymal stem cells in MRL/lpr mice

Ma, L., Aijima, R., Hoshino, Y., Yamaza, H., Tomoda, E., Tanaka, Y., Sonoda, S., Song, G., Zhao, W., Nonaka, K., Shi, S. & Yamaza, T., May 27 2015, In : Stem Cell Research and Therapy. 6, 1, 104.

Research output: Contribution to journalArticle

Inbred MRL lpr Mouse
Mesenchymal Stem Cell Transplantation
Interleukin-17
Stem cells
Mesenchymal Stromal Cells
2014
8 Citations (Scopus)

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair

Yoshizaki, K., Hu, L., Nguyen, T., Sakai, K., He, B., Fong, C., Yamada, Y., Bikle, D. D. & Oda, Y., Jun 20 2014, In : PloS one. 9, 6, e99991.

Research output: Contribution to journalArticle

Ablation
Stem cells
hairs
Tooth
teeth
6 Citations (Scopus)

Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif

Suzuki, S., Kobuke, S., Haruyama, N., Hoshino, H., Kulkarni, A. B. & Nishimura, F., Nov 14 2014, In : PloS one. 9, 11, e112490.

Research output: Contribution to journalArticle

integrins
Integrins
adhesives
Adhesives
teeth
9 Citations (Scopus)
Streptococcus mutans
Streptococcus pyogenes
mutants
gene
Genes
10 Citations (Scopus)

Biocatalytic asymmetric phosphorylation of mevalonate

Matsumi, R., Hellriegel, C., Schoenenberger, B., Milesi, T., Van Der Oost, J. & Wohlgemuth, R., Mar 17 2014, In : RSC Advances. 4, 25, p. 12989-12994 6 p.

Research output: Contribution to journalArticle

mevalonate kinase
Mevalonic Acid
Phosphorylation
Phosphates
Biocatalysts
1 Citation (Scopus)

Clinical approach to a suspected case of first branchial arch syndrome

Yamaguchi, N., Nakamura, S., Yamaza, H., Nishigaki, S., Masuda, K., Yanagita, K. I. & Nonaka, K., 2014, In : Case Reports in Medicine. 2014, 506804.

Research output: Contribution to journalArticle

Branchial Region
Cephalometry
Ear
Hearing Loss
Goldenhar Syndrome

Compressive force-produced CCN2 induces osteocyte apoptosis through ERK1/2 pathway

Hoshi, K., Kawaki, H., Takahashi, I., Takeshita, N., Seiryu, M., Murshid, S. A., Masuda, T., Anada, T., Kato, R., Kitaura, H., Suzuki, O. & Takano-Yamamoto, T., Jan 1 2014, In : Transactions of Japanese Society for Medical and Biological Engineering. 52, p. O-237-O-238

Research output: Contribution to journalArticle

Cell death
Phosphorylation
Proteins
Antibodies
Cell culture
17 Citations (Scopus)

Compressive force-produced CCN2 induces osteocyte apoptosis through ERK1/2 pathway

Hoshi, K., Kawaki, H., Takahashi, I., Takeshita, N., Seiryu, M., Murshid, S. A., Masuda, T., Anada, T., Kato, R., Kitaura, H., Suzuki, O. & Takano-Yamamoto, T., May 2014, In : Journal of Bone and Mineral Research. 29, 5, p. 1244-1257 14 p.

Research output: Contribution to journalArticle

Osteocytes
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Apoptosis
Connective Tissue Growth Factor
26 Citations (Scopus)

Distinct composition of the oral indigenous microbiota in South Korean and Japanese adults

Takeshita, T., Matsuo, K., Furuta, M., Shibata, Y., Fukami, K., Shimazaki, Y., Akifusa, S., Han, D. H., Kim, H. D., Yokoyama, T., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., Nov 11 2014, In : Scientific reports. 4, 6990.

Research output: Contribution to journalArticle

Microbiota
Veillonella
Prevotella
Haemophilus
Neisseria
8 Citations (Scopus)

Effects of sliding velocity on friction an in vitro study at extremely low sliding velocity approximating orthodontic tooth movement

Yanase, Y., Ioi, H., Nishioka, M. & Takahashi, I., May 2014, In : Angle Orthodontist. 84, 3, p. 451-458 8 p.

Research output: Contribution to journalArticle

Tooth Movement Techniques
Friction
Stainless Steel
Orthodontics
In Vitro Techniques
7 Citations (Scopus)

Effects of vermilion height on lip esthetics in Japanese and Korean orthodontists and orthodontic patients

Ioi, H., Kang, S., Shimomura, T., Kim, S. S., Park, S. B., Son, W. S. & Takahashi, I., Mar 1 2014, In : Angle Orthodontist. 84, 2, p. 239-245 7 p.

Research output: Contribution to journalArticle

Lip
Orthodontics
Esthetics
Visual Analog Scale
Orthodontists
12 Citations (Scopus)

Epiprofin orchestrates epidermal keratinocyte proliferation and differentiation

Nakamura, T., Yoshitomi, Y., Sakai, K., Patel, V., Fukumoto, S. & Yamada, Y., Jan 1 2014, In : Journal of cell science. 127, 24, p. 5261-5272 12 p.

Research output: Contribution to journalArticle

Open Access
Keratinocytes
Epidermis
Cell Cycle
Notch1 Receptor
Stem Cells
15 Citations (Scopus)
Calcium Sulfate
Carbonates
Gypsum
Apatite
Phosphates
12 Citations (Scopus)

Factors associated with dry mouth in dependent Japanese elderly

Kakudate, N., Muramatsu, T., Endoh, M., Satomura, K., Koseki, T., Sato, Y., Ito, K., Ogasawara, T., Nakamura, S., Kishimoto, E., Kashiwazaki, H., Yamashita, Y., Uchiyama, K., Nishihara, T., Kiyohara, Y. & Kakinoki, Y., Mar 1 2014, In : Gerodontology. 31, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Mouth
Diuretics
Antidepressive Agents
Mouth Breathing
Oral Health
32 Citations (Scopus)

Identification of the microbiota in carious dentin lesions using 16S rRNA gene sequencing

Obata, J., Takeshita, T., Shibata, Y., Yamanaka, W., Unemori, M., Akamine, A. & Yamashita, Y., Aug 1 2014, In : PloS one. 9, 8, e103712.

Research output: Contribution to journalArticle

Atopobium
Microbiota
Dental Caries
Propionibacterium
rRNA Genes
18 Citations (Scopus)

Inequalities of dental prosthesis use under universal healthcare insurance

Matsuyama, Y., Aida, J., Takeuchi, K., Tsakos, G., Watt, R. G., Kondo, K. & Osaka, K., Jan 1 2014, In : Community Dentistry and Oral Epidemiology. 42, 2, p. 122-128 7 p.

Research output: Contribution to journalArticle

Dental Prosthesis
Insurance
Delivery of Health Care
Tooth
Japan
7 Citations (Scopus)

Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells

Kihara, M., Kiyoshima, T., Nagata, K., Wada, H., Fujiwara, H., Hasegawa, K., Someya, H., Takahashi, I. & Sakai, H., Jul 31 2014, In : PloS one. 9, 7, e103928.

Research output: Contribution to journalArticle

Enamels
Tooth
teeth
tooth enamel
epithelial cells
9 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using internal transcribed spacer region

Ieda, S., Moriyama, M., Takashita, T., Maehara, T., Imabayashi, Y., Shinozaki, S., Tanaka, A., Hayashida, J. N., Furukawa, S., Ohta, M., Yamashita, Y. & Nakamura, S., Jun 30 2014, In : PloS one. 9, 6, e101156.

Research output: Contribution to journalArticle

Oral Candidiasis
candidiasis
Fungi
internal transcribed spacers
mouth
39 Citations (Scopus)

Nutritional status and dysphagia risk among community-dwelling frail older adults

Takeuchi, K., Aida, J., Ito, K., Furuta, M., Yamashita, Y. & Osaka, K., Jan 1 2014, In : Journal of Nutrition, Health and Aging. 18, 4, p. 352-357 6 p.

Research output: Contribution to journalArticle

Independent Living
Frail Elderly
Deglutition Disorders
Nutritional Status
Malnutrition
48 Citations (Scopus)

Oral administration of osteocalcin improves glucose utilization by stimulating glucagon-like peptide-1 secretion

Mizokami, A., Yasutake, Y., Higashi, S., Kawakubo-Yasukochi, T., Chishaki, S., Takahashi, I., Takeuchi, H. & Hirata, M., Sep 16 2014, In : Bone. 69, p. 68-79 12 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Osteocalcin
Oral Administration
Glucose
Insulin
11 Citations (Scopus)

Regulation of osteoclastogenesis through Tim-3: Possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction

Moriyama, K., Kukita, A., Li, Y. J., Uehara, N., Zhang, J. Q., Takahashi, I. & Kukita, T., Nov 5 2014, In : Laboratory Investigation. 94, 11, p. 1200-1211 12 p.

Research output: Contribution to journalArticle

Galectins
Galectin 3
Osteogenesis
Bone and Bones
Carbohydrates
20 Citations (Scopus)

Relationship between increases in BMI and changes in periodontal status: A prospective cohort study

Ekuni, D., Mizutani, S., Kojima, A., Tomofuji, T., Irie, K., Azuma, T., Yoneda, T., Furuta, M., Eshima, N., Iwasaki, Y. & Morita, M., Aug 2014, In : Journal of Clinical Periodontology. 41, 8, p. 772-778 7 p.

Research output: Contribution to journalArticle

Periodontal Index
Oral Health
Body Mass Index
Cohort Studies
Prospective Studies
4 Citations (Scopus)

Supervised machine learning-based classification of oral malodor based on the microbiota in saliva samples

Nakano, Y., Takeshita, T., Kamio, N., Shiota, S., Shibata, Y., Suzuki, N., Yoneda, M., Hirofuji, T. & Yamashita, Y., Feb 1 2014, In : Artificial Intelligence in Medicine. 60, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

Microbiota
Saliva
Learning systems
Decision Trees
Support vector machines
2013

Adiponectin and Macrophage

Akifusa, S. & Yamashita, Y., 2013, Nova Science Publishers, Inc. 21 p.

Research output: Book/ReportBook

Adiponectin
Macrophages
Adipokines
Adipose Tissue
Adipocytes
3 Citations (Scopus)

Application of a tooth-surface coating material to teeth with discolored crowns

Hashimura, T., Yamada, A., Iwamoto, T., Arakaki, M., Saito, K. & Fukumoto, S., Jan 1 2013, In : pediatric dental journal. 23, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

Crowns
Tooth
Color
Shear Strength
Tooth Discoloration
27 Citations (Scopus)

Bacterial adhesion affinities of various implant abutment materials

Yamane, K., Ayukawa, Y., Takeshita, T., Furuhashi, A., Yamashita, Y. & Koyano, K., Dec 2013, In : Clinical Oral Implants Research. 24, 12, p. 1310-1315 6 p.

Research output: Contribution to journalArticle

Bacterial Adhesion
Platinum
Gold Alloys
Bacterial Structures
Splints
1 Citation (Scopus)

Biological roles of gap junction proteins in cartilage and bone development

Iwamoto, T., Ishikawa, M., Ono, M., Nakamura, T., Fukumoto, S. & Yamada, Y., Feb 2013, In : journal of oral biosciences. 55, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

Connexins
Bone Development
Cartilage
Bone
Neurology
4 Citations (Scopus)

Continual gram-negative bacterial challenge accelerates stroke onset in stroke-prone spontaneously hypertensive rats

Kawato, T., Tanaka, H., Tabuchi, M., Ooshima, K., Nakai, K., Yamashita, Y. & Maeno, M., Jan 7 2013, In : Clinical and Experimental Hypertension. 35, 1, p. 28-34 7 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Stroke
Lipopolysaccharides
Piloerection
Hyperkinesis
14 Citations (Scopus)

Crystal structures of the carbamoylated and cyanated forms of HypE for [NiFe] hydrogenase maturation

Tominaga, T., Watanabe, S., Matsumi, R., Atomi, H., Imanaka, T. & Miki, K., Dec 17 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 51, p. 20485-20490 6 p.

Research output: Contribution to journalArticle

Crystal structure
Dehydration
Cysteine
Protons
Adenosine Triphosphate
4 Citations (Scopus)

Dental caries is correlated with knowledge of comprehensive food education in Japanese university students

Ekuni, D., Tomofuji, T., Mizutani, S., Furuta, M., Irie, K., Azuma, T., Kojima, A., Iwasaki, Y. & Morita, M., Apr 1 2013, In : Asia Pacific Journal of Clinical Nutrition. 22, 2, p. 312-318 7 p.

Research output: Contribution to journalArticle

Dental Caries
Students
Education
Food
DMF Index
31 Citations (Scopus)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., May 20 2013, In : Bioscience reports. 33, 2, p. 217-227 11 p., e00021.

Research output: Contribution to journalArticle

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 2013, In : Bioscience Reports. 33, 2

Research output: Contribution to journalArticle

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase
17 Citations (Scopus)

Effect of mouth cleaning with hinokitiol-containing gel on oral malodor: A randomized, open-label pilot study

Iha, K., Suzuki, N., Yoneda, M., Takeshita, T. & Hirofuji, T., Oct 1 2013, In : Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 116, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

Mouth
Gels
Hydrogen Sulfide
Gingiva
Tongue
6 Citations (Scopus)

Effects of eating behaviors on being overweight in Japanese university students: A cross-sectional survey at the Okayama University

Ekuni, D., Furuta, M., Tomofuji, T., Irie, K., Azuma, T., Iwasaki, Y. & Morita, M., Jul 1 2013, In : Asia-Pacific Journal of Public Health. 25, 4, p. 326-334 9 p.

Research output: Contribution to journalArticle

Feeding Behavior
Cross-Sectional Studies
Eating
Students
Odds Ratio
6 Citations (Scopus)

Effects of extraction of four premolars on vermilion height and lip area in patients with bimaxillary protrusion

Trisnawaty, N., Ioi, H., Kitahara, T., Suzuki, A. & Takahashi, I., Aug 1 2013, In : European Journal of Orthodontics. 35, 4, p. 521-528 8 p.

Research output: Contribution to journalArticle

Bicuspid
Lip
Orthodontics
Control Groups
Therapeutics

Effects of four premolar extractions on vermilion height and lip area during a posed smile in patients with bimaxillary protrusion.

Trisnawaty, N., Ioi, H., Kitahara, T., Suzuki, A. & Takahashi, I., Jan 1 2013, In : Unknown Journal. 29, 2, p. 176-183 8 p.

Research output: Contribution to journalArticle

Bicuspid
Lip
Orthodontics
Control Groups
Therapeutics
9 Citations (Scopus)

Effects of vertical positions of anterior teeth on smile esthetics in Japanese and Korean orthodontists and orthodontic patients

Ioi, H., Kang, S., Shimomura, T., Kim, S. S., Park, S. B., Son, W. S. & Takahashi, I., Aug 2013, In : Journal of Esthetic and Restorative Dentistry. 25, 4, p. 274-282 9 p.

Research output: Contribution to journalArticle

Orthodontics
Esthetics
Tooth
Lip
Orthodontists
1 Citation (Scopus)

Fabrication of spherical carbonate apatite using calcium sulfate as a precursor by W/O emulsion method

Nomura, S., Tsuru, K., Matsuya, S., Takahashi, I. & Ishikawa, K., Jan 1 2013, Bioceramics 24. 1 ed. p. 78-81 4 p. (Key Engineering Materials; vol. 529-530, no. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Calcium Sulfate
Apatite
Emulsions
Carbonates
Calcium
24 Citations (Scopus)

Gender differences in the association between metabolic syndrome and periodontal disease: The Hisayama Study

Furuta, M., Shimazaki, Y., Takeshita, T., Shibata, Y., Akifusa, S., Eshima, N., Kiyohara, Y., Ninomiya, T., Hirakawa, Y., Mukai, N., Nagata, M. & Yamashita, Y., Aug 1 2013, In : Journal of Clinical Periodontology. 40, 8, p. 743-752 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Periodontal Diseases
Structural Models
Logistic Models
Regression Analysis
3 Citations (Scopus)

Genetics of supernumerary tooth formation

Nakamura, T. & Fukumoto, S., Nov 2013, In : journal of oral biosciences. 55, 4, p. 180-183 4 p.

Research output: Contribution to journalReview article

Supernumerary Tooth
Tooth
Molecules
Epithelium
Genetics
14 Citations (Scopus)

Identification and structure of a novel archaeal HypB for [NiFe] hydrogenase maturation

Sasaki, D., Watanabe, S., Matsumi, R., Shoji, T., Yasukochi, A., Tagashira, K., Fukuda, W., Kanai, T., Atomi, H., Imanaka, T. & Miki, K., May 27 2013, In : Journal of Molecular Biology. 425, 10, p. 1627-1640 14 p.

Research output: Contribution to journalArticle

Nickel
Adenosine Triphosphate
Adenosine Diphosphate
Thermococcales
Adenosine Triphosphatases
22 Citations (Scopus)

Immune therapeutic potential of stem cells from human supernumerary teeth

Makino, Y., Yamaza, H., Akiyama, K., Ma, L., Hoshino, Y., Nonaka, K., Terada, Y., Kukita, T., Shi, S. & Yamaza, T., Jul 1 2013, In : Journal of Dental Research. 92, 7, p. 609-615 7 p.

Research output: Contribution to journalArticle

Supernumerary Tooth
Inbred MRL lpr Mouse
Stem Cells
Th17 Cells
Stem Cell Transplantation
78 Citations (Scopus)
Aptitude
Oral Health
Deglutition
Home Care Services
Activities of Daily Living
13 Citations (Scopus)

Involvement of the novel two-component nsrrs and lcrrs systems in distinct resistance pathways against nisin a and nukacin isk-1 in streptococcus mutans

Kawada-Matsuo, M., Oogai, Y., Zendo, T., Nagao, J., Shibata, Y., Yamashita, Y., Ogura, Y., Hayashi, T., Sonomoto, K. & Komatsuzawa, H., Aug 1 2013, In : Applied and environmental microbiology. 79, 15, p. 4751-4755 5 p.

Research output: Contribution to journalArticle

Nisin
Streptococcus mutans
nisin
Bacteriocins
bacteriocins
12 Citations (Scopus)

Multiple functional involvement of Thymosin beta-4 in tooth germ development

Ookuma, Y. F., Kiyoshima, T., Kobayashi, I., Nagata, K., Wada, H., Fujiwara, H., Yamaza, H., Nonaka, K. & Sakai, H., Feb 1 2013, In : Histochemistry and Cell Biology. 139, 2, p. 355-370 16 p.

Research output: Contribution to journalArticle

Tooth Germ
Mandible
Oligodeoxyribonucleotides
Epithelial Cells
Sulfur

Oral Health and Swallowing Problems

Furuta, M. & Yamashita, Y., Sep 15 2013, In : Current Physical Medicine and Rehabilitation Reports. 1, p. 216-222

Research output: Contribution to journalReview article

Oral Health
Deglutition
Eating
Oral Hygiene
Mastication
75 Citations (Scopus)

Osteocalcin Induces Release of Glucagon-Like Peptide-1 and Thereby Stimulates Insulin Secretion in Mice

Mizokami, A., Yasutake, Y., Gao, J., Matsuda, M., Takahashi, I., Takeuchi, H. & Hirata, M., Feb 20 2013, In : PloS one. 8, 2, e57375.

Research output: Contribution to journalArticle

glucagon-like peptide 1
osteocalcin
Glucagon-Like Peptide 1
insulin secretion
Osteocalcin
18 Citations (Scopus)

Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-β signaling

Aukkarasongsup, P., Haruyama, N., Matsumoto, T., Shiga, M. & Moriyama, K., Nov 8 2013, In : Biochemical and Biophysical Research Communications. 441, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Periodontal Ligament
Ligaments
Apoptosis
Small Interfering RNA