Organic and Biological Chemistry

Research Output 1983 2019

1983
18 Citations (Scopus)

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome p-450's from adrenal cortex

Ogishima, T., Okada, Y., Kominami, S., Takemori, S. & Omura, T., Nov 1983, In : Journal of Biochemistry. 94, 5, p. 1711-1714 4 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Cytochromes
Cytochrome P-450 Enzyme System
Amino Acid Sequence
Amino Acids
1984
6 Citations (Scopus)

Fractionation of mammalian tissue mRNAs by high-performance gel filtration chromatography

Ogishima, T., Okada, Y. & Omura, T., May 1 1984, In : Analytical Biochemistry. 138, 2, p. 309-313 5 p.

Research output: Contribution to journalArticle

Fractionation
Chromatography
Gel Chromatography
Gels
Tissue
4 Citations (Scopus)

Presence of a prepiece at the NH2-terminai end of pre-cytochrome P-450(SCC) peptide

Ogishima, T., Okada, Y. & Omura, T., Jan 1 1984, In : Journal of biochemistry. 95, 5, p. 1525-1528 4 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Peptides
Radio
Amino Acids
Acids
1985
48 Citations (Scopus)

Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria

Ito, A., Ogishima, T., Ou, W., Omura, T., Aoyagi, H., Lee, S., Mihara, H. & Izumiya, N., Jan 1 1985, In : Journal of Biochemistry. 98, 6, p. 1571-1582 12 p.

Research output: Contribution to journalArticle

Enzyme Precursors
Mitochondria
Peptides
Basic Amino Acids
Membranes
35 Citations (Scopus)

Import and processing of the precursor of cytochrome P-450(SCC) by bovine adrenal cortex mitochondria

Ogishima, T., Okada, Y. & Omura, T., Jan 1 1985, In : Journal of biochemistry. 98, 3, p. 781-791 11 p.

Research output: Contribution to journalArticle

Mitochondria
Adrenal Cortex
Cytochrome P-450 Enzyme System
Membranes
Processing
1989
93 Citations (Scopus)

Highly Enantioselective Dihydroxylation of Trans-Disubstituted and Monosubstituted Olefins

Oishi, T. & Hirama, M., Dec 1 1989, In : Journal of Organic Chemistry. 54, 25, p. 5834-5835 2 p.

Research output: Contribution to journalLetter

Osmium
Alkenes
Ligands
Oxidation
1990
2 Citations (Scopus)

Asymmetric OsO4 Oxidation with 2,2’-Bipyrrolidine Ligands

Oishi, T. & Hirama, M., Jan 1 1990, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 48, 11, p. 1006-1007 2 p.

Research output: Contribution to journalArticle

Ligands
Oxidation
618 Citations (Scopus)

Catalytic asymmetric epoxidation of unfunctionalized olefins

Irie, R., Noda, K., Ito, Y., Matsumoto, N. & Katsuki, T., Jan 1 1990, In : Tetrahedron Letters. 31, 50, p. 7345-7348 4 p.

Research output: Contribution to journalArticle

Epoxidation
Enantioselectivity
Alkenes
Manganese
Ligands
1991
9 Citations (Scopus)

A formal total synthesis of aplysiatoxin

Okamura, H., Kuroda, S., Ikegami, S., Ito, Y., Katsuki, T. & Yamaguchi, M., Sep 16 1991, In : Tetrahedron Letters. 32, 38, p. 5141-5142 2 p.

Research output: Contribution to journalArticle

Stereochemistry
Communication
aplysiatoxin
18 Citations (Scopus)

A Highly Stereoselective Synthesis of (3A,4iS)-Statine and (SS^AJ-Cyclohexylstatine^

Takemoto, Y., Matsumoto, T., Ito, Y. & Terashima, S., Jan 1 1991, In : Chemical and Pharmaceutical Bulletin. 39, 9, p. 2425-2428 4 p.

Research output: Contribution to journalArticle

Acetals
Titanium
Phenylalanine
Renin
Aldehydes
124 Citations (Scopus)

Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism

Ogishima, T., Shibata, H., Shimada, H., Mitani, F., Suzuki, H., Saruta, T. & Ishimura, Y., Sep 6 1991, In : Journal of Biological Chemistry. 266, 17, p. 10731-10734 4 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Hyperaldosteronism
Cytochrome P-450 Enzyme System
Genes
Aldosterone
176 Citations (Scopus)

Catalytic asymmetric epoxidation of unfunctionalized olefins using chiral (salen)manganese(III) complexes

Irie, R., Noda, K., Ito, Y., Matsumoto, N. & Katsuki, T., 1991, In : Tetrahedron: Asymmetry. 2, 7, p. 481-494 14 p.

Research output: Contribution to journalArticle

epoxidation
Epoxidation
Alkenes
Manganese
alkenes
45 Citations (Scopus)

Catalytic epoxidation with molecular oxygen using nickel complex

Irie, R., Ito, Y. & Katsuki, T., Nov 18 1991, In : Tetrahedron Letters. 32, 47, p. 6891-6894 4 p.

Research output: Contribution to journalArticle

Epoxidation
Molecular oxygen
Alkenes
Nickel
Oxygen

Donor Ligand Effect in Asymmetric Epoxidation of Unfunctionalized Olefins with Chiral Salen Complexes

Irie, R., Ito, Y. & Katsuki, T., Apr 1991, In : Synlett. 1991, 4, p. 265-266 2 p.

Research output: Contribution to journalArticle

Epoxidation
Alkenes
Ligands
Enantioselectivity
Manganese

Enantioselective epoxidation of olefins with chiral (salen)manganese(III) complexes bearing 4-methyl-3-[(R)-1-phenylpropyl]salicylideneamine as a constituent

Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

ethylenediamine
Bearings (structural)
Epoxidation
Alkenes
Manganese

Enantioselective epoxidation of olefins with chiral (Salen)manganese(III) complexes bearing 4-Methyl-3-[(R)-l-phenylpropyl] salicylideneamine as a constituent

Hosoya, N., Ine, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

ethylenediamine
Bearings (structural)
Epoxidation
Alkenes
Manganese
145 Citations (Scopus)

Enantioselective epoxidation of unfunctionalized olefins using chiral (salen)manganese(III) complexes

Irie, R., Noda, K., Ito, Y. & Katsuki, T., Feb 18 1991, In : Tetrahedron Letters. 32, 8, p. 1055-1058 4 p.

Research output: Contribution to journalArticle

Stilbenes
Epoxidation
Enantioselectivity
Alkenes
Manganese
56 Citations (Scopus)

Regulation of aldosterone synthase cytochrome P-450 in rat adrenals by angiotensin II and potassium

Shibata, H., Ogishima, T., Mitani, F., Suzuki, H., Murakami, M., Saruta, T. & Ishimura, Y., May 1 1991, In : Endocrinology. 128, 5, p. 2534-2539 6 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Angiotensin II
Potassium
Diet
Aldosterone
1992
32 Citations (Scopus)

Highly Enantioselective Epoxidation of 2,2-Dimethylchromenes

Hatayama, A., Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., May 1992, In : Synlett. 1992, 5, p. 407-409 3 p.

Research output: Contribution to journalArticle

ethylenediamine
Epoxidation
Enantioselectivity
Manganese
154 Citations (Scopus)

Zone-specific expression of aldosterone synthase cytochrome p-450 and cytochrome p-45011β in rat adrenal cortex: Histochemical basis for the functional zonation

Ogishima, T., Suzuki, H., Hata, J. I., Mitani, F. & Ishimura, Y., May 1992, In : Endocrinology. 130, 5, p. 2971-2977 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Adrenal Cortex
Cytochromes
Zona Glomerulosa
Aldosterone
1993
26 Citations (Scopus)

A formal synthesis of aplysiatoxin: enantioselective synthesis of kishi's aldehyde

Okamura, H., Kuroda, S., Ikegami, S., Tomita, K., Sugimoto, Y. I., Sakaguchi, S. I., Ito, Y., Katsuki, T. & Yamaguchi, M., 1993, In : Tetrahedron. 49, 46, p. 10531-10554 24 p.

Research output: Contribution to journalArticle

Aldehydes
Neoplasms
aplysiatoxin

Asymmetric aziridination by using optically active (Salen)manganese(III) complexes

Noda, K., Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., Jul 1993, In : Synlett. 1993, 7, p. 469-471 3 p.

Research output: Contribution to journalArticle

Styrene
Manganese
disalicylaldehyde ethylenediamine

Chiral Leaving Group: Synthesis of Optically Active Benzimidazole and its Application to Asymmetric Acylation

Ogata, M., Yoshimura, T., Fujii, H., Ito, Y. & Katsuki, T., Oct 1993, In : Synlett. 1993, 10, p. 728-730 3 p.

Research output: Contribution to journalArticle

Acylation
Amides
Derivatives
benzimidazole
mandelic acid
14 Citations (Scopus)

Molecular Cloning of the Smaller Subunit (P52) of Rat Liver Mitochondrial Processing Protease

Kitada, S., Niidome, T., Nagano, T., Ogishima, T. & Ito, A., Jan 1 1993, In : Biochemical and Biophysical Research Communications. 190, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

Cloning
Molecular Cloning
Liver
Yeast
Rats
2 Citations (Scopus)

Synthesis of the 1β-Methylcarbapenem Key Intermediates

Ito, Y. & Terashima, S., Jan 1 1993, Studies in Natural Products Chemistry. p. 145-177 33 p. (Studies in Natural Products Chemistry; vol. 12).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 beta-methylcarbapenem
1994
128 Citations (Scopus)

A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: Histochemical detection and possible physiological role

Mitani, F., Suzuki, H., Hata, J. I., Ogishima, T., Shimada, H. & Ishimura, Y., Jul 1994, In : Endocrinology. 135, 1, p. 431-438 8 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Adrenal Cortex Hormones
Enzymes
Cytochrome P-450 CYP11B2
Zona Fasciculata
60 Citations (Scopus)

Arginine residues in the extension peptide are required for cleavage of a precursor by mitochondrial processing peptidase. Demonstration using synthetic peptide as a substrate

Niidome, T., Kitada, S., Shimokata, K., Ogishima, T. & Ito, A., Jan 1 1994, In : Journal of Biological Chemistry. 269, 40, p. 24719-24722 4 p.

Research output: Contribution to journalArticle

Arginine
Demonstrations
Peptides
Substrates
Amino Acids
Titanium
structural analysis
Structural analysis
reagents
titanium
1995
46 Citations (Scopus)

Analysis of elements in the substrate required for processing by mitochondrial processing peptidase

Ogishima, T., Niidome, T., Shimokata, K., Kitada, S. & Ito, A., Dec 22 1995, In : Journal of Biological Chemistry. 270, 51, p. 30322-30326 5 p.

Research output: Contribution to journalArticle

Arginine
Peptide Hydrolases
Proline
Glycine
Substrates
56 Citations (Scopus)

A putative metal-binding site in the β subunit of rat mitochondrial processing peptidase is essential for its catalytic activity

Kitada, S., Shimokata, K., Niidome, T., Ogishima, T. & Ito, A., Jan 1 1995, In : Journal of biochemistry. 117, 6, p. 1148-1150 3 p.

Research output: Contribution to journalArticle

Rats
Catalyst activity
Metals
Binding Sites
Catalytic Domain
1996
60 Citations (Scopus)

Enantioselective Epoxidation of 2,2-Dimethylchromenes Using Achiral Mn-Salen Complex as a Catalyst in the Presence of Chiral Amine

Hashihayata, T., Ito, Y. & Katsuki, T., 1996, In : Synlett. 1996, 11, p. 1079-1081 3 p.

Research output: Contribution to journalArticle

Sparteine
Epoxidation
Manganese
Amines
Derivatives
11 Citations (Scopus)

Evidence for 54-kD protein in chicken kidney as a cytochrome P450 with a high molecular activity of 25-hydroxyvitamin D3 1β-hydroxylase

Wakino, S., Meguro, M., Suzuki, H., Saruta, T., Ogishima, T., Shimada, H., Ishimura, Y., Shinki, T. & Suda, T., Jan 1996, In : Gerontology. 42, 1, p. 67-77 11 p.

Research output: Contribution to journalArticle

Calcifediol
Mixed Function Oxygenases
Cytochrome P-450 Enzyme System
Chickens
Kidney
34 Citations (Scopus)

Immunochemical identification of the pssA gene product as phosphatidylserine synthase I of Chinese hamster ovary cells

Saito, K., Kuge, O., Akamatsu, Y. & Nishijima, M., Oct 21 1996, In : FEBS Letters. 395, 2-3, p. 262-266 5 p.

Research output: Contribution to journalArticle

Cricetulus
Ovary
Mitochondria
Genes
Cells
31 Citations (Scopus)

Role of basic amino acids in the cleavage of synthetic peptide substrates by mitochondrial processing peptidase

Song, M. C., Shimokata, K., Kitada, S., Ogishima, T. & Ito, A., Jan 1 1996, In : Journal of biochemistry. 120, 6, p. 1163-1166 4 p.

Research output: Contribution to journalArticle

Basic Amino Acids
Ornithine-Oxo-Acid Transaminase
Peptides
Substrates
Processing
1997

Processing of mitochondrial protein precursors

Ito, A., Ogishima, T. & Kitada, S., Jan 1 1997, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 42, 14 Suppl, p. 2362-2367 6 p.

Research output: Contribution to journalReview article

Metalloendopeptidases
Protein Precursors
Mitochondrial Proteins
Mitochondria
17 Citations (Scopus)

Remarkable solvent effect on the enantioface selectivity in the Diels- Alder reaction catalyzed by an aluminum complex of a newly prepared chiral menthol derivative

Naraku, G., Hori, K., Ito, Y. & Katsuki, T., Nov 24 1997, In : Tetrahedron Letters. 38, 47, p. 8231-8232 2 p.

Research output: Contribution to journalArticle

Menthol
Enantiomers
Cycloaddition Reaction
Aluminum
Reaction products
22 Citations (Scopus)

Substrate recognition by mitochondrial processing peptidase toward the malate dehydrogenase precursor

Shimokata, K., Nishio, T., Song, M. C., Kitada, S., Ogishima, T. & Ito, A., Jan 1 1997, In : Journal of biochemistry. 122, 5, p. 1019-1023 5 p.

Research output: Contribution to journalArticle

Malate Dehydrogenase
Arginine
Peptides
Substrates
Protein Precursors
95 Citations (Scopus)

The first asymmetric epoxidation using a combination of achiral (salen)manganese(III) complex and chiral amine

Hashihayata, T., Ito, Y. & Katsuki, T., Jul 14 1997, In : Tetrahedron. 53, 28, p. 9541-9552 12 p.

Research output: Contribution to journalArticle

sulfoxide
Epoxidation
Manganese
Amines
Sparteine
1998
21 Citations (Scopus)

Cooperative formation of a substrate binding pocket by α- and β- subunits of mitochondrial processing peptidase

Kojima, K., Kitada, S., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32542-32546 5 p.

Research output: Contribution to journalArticle

Substrates
Peptides
Arginine
Protein Precursors
mitochondrial processing peptidase
38 Citations (Scopus)

Enzymatic synthesis of ω-amino-ceramide: Preparation of a sensitive fluorescent substrate for ceramidase

Tani, M., Kita, K., Komori, H., Nakagawa, T. & Ito, M., Oct 15 1998, In : Analytical Biochemistry. 263, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

Ceramidases
Ceramides
Trifluoroacetic Acid
Substrates
Enzymes
31 Citations (Scopus)

Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase

Kitada, S., Kojima, K., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32547-32553 7 p.

Research output: Contribution to journalArticle

Glutamic Acid
Substrates
Peptides
Glutamates
Mutation
16 Citations (Scopus)
Serine
Peptide Hydrolases
Peptides
Arginine
Substrates
81 Citations (Scopus)

Purification and characterization of a novel ceramidase from pseudomonas aeruginosa

Okino, N., Tani, M., Imayama, S. & Ito, M., Jun 5 1998, In : Journal of Biological Chemistry. 273, 23, p. 14368-14373 6 p.

Research output: Contribution to journalArticle

Ceramidases
Pseudomonas aeruginosa
Ceramides
Purification
Enzymes
37 Citations (Scopus)

Role of α-subunit of mitochondrial processing peptidase in substrate recognition

Shimokata, K., Kitada, S., Ogishima, T. & Ito, A., Sep 25 1998, In : Journal of Biological Chemistry. 273, 39, p. 25158-25163 6 p.

Research output: Contribution to journalArticle

Substrates
Processing
Adrenodoxin
Acidic Amino Acids
Peptides
62 Citations (Scopus)
ethylenediamine
Epoxidation
Manganese
Epoxy Compounds
Ions
1999
8 Citations (Scopus)
Arginine
Amino Acids
Protein Precursors
Mitochondrial Proteins
Peptide Hydrolases
204 Citations (Scopus)

Asymmetric catalysis of new generation chiral metallosalen complexes

Ito, Y. & Katsuki, T., Apr 1 1999, In : Bulletin of the Chemical Society of Japan. 72, 4, p. 603-619 17 p.

Research output: Contribution to journalArticle

Catalysis
Epoxidation
Manganese
Derivatives
Styrene
31 Citations (Scopus)

cis-selective aziridination of cis- or trans-α,β-unsaturated amides using diaziridine

Hori, K., Sugihara, H., Ito, Y. N. & Katsuki, T., Jul 9 1999, In : Tetrahedron Letters. 40, 28, p. 5207-5210 4 p.

Research output: Contribution to journalArticle

Amides
Nitrogen
Atoms
Geometry
Substrates

Importance of ligand Phe-phenyl group for activation of thrombin receptor

Fujita, T., Nose, T., Matsushima, A., Costa, T. & Shimohigashi, Y., 1999, Peptide Science 1998. p. 33-36

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

22 Citations (Scopus)
Sphingolipids
Sphingomyelins
Hydrolysis
Assays
Carrier Proteins