Organic and Biological Chemistry

Research Output

Article

Confirmation of the absolute configuration at C45 of amphidinol 3

Manabe, Y., Ebine, M., Matsumori, N., Murata, M. & Oishi, T., Dec 3 2012, In : Journal of Natural Products. 75, 11, p. 2003-2006 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
7 Citations (Scopus)
3 Citations (Scopus)

Convergent syntheses of the WXYZ ring of maitotoxin and the HIJK ring of brevisulcenal-F

Osato, N., Onoue, H., Toma, Y., Torikai, K., Ebine, M., Satake, M. & Oishi, T., Jan 1 2018, In : Chemistry Letters. 47, 3, p. 265-268 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Convergent synthesis of the ABCDE ring system of ciguatoxin CTX3C

Maruyama, M., Inoue, M., Oishi, T., Oguri, H., Ogasawara, Y., Shindo, Y. & Hirama, M., Mar 4 2002, In : Tetrahedron. 58, 10, p. 1835-1851 17 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Convergent synthesis of the HIJKLM ring fragment of ciguatoxin CTX3C

Uehara, H., Oishi, T., Inoue, M., Shoji, M., Nagumo, Y., Kosaka, M., Le Brazidec, J. Y. & Hirama, M., Aug 5 2002, In : Tetrahedron. 58, 32, p. 6493-6512 20 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Convergent total synthesis of gymnocin-A and evaluation of synthetic analogues

Tsukano, C., Ebine, M. & Sasaki, M., Mar 30 2005, In : Journal of the American Chemical Society. 127, 12, p. 4326-4335 10 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Cooperative formation of a substrate binding pocket by α- and β- subunits of mitochondrial processing peptidase

Kojima, K., Kitada, S., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32542-32546 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Cooperative function of Fmp30, Mdm31, and Mdm32 in Ups1-independent cardiolipin accumulation in the yeast Saccharomyces cerevisiae

Miyata, N., Goda, N., Matsuo, K., Hoketsu, T. & Kuge, O., Dec 1 2017, In : Scientific reports. 7, 1, 16447.

Research output: Contribution to journalArticle

6 Citations (Scopus)

COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1

Ban-Ishihara, R., Tomohiro-Takamiya, S., Tani, M., Baudier, J., Ishihara, N. & Kuge, O., Oct 7 2015, In : FEBS Letters. 589, 20, p. 3126-3132 7 p., 37349.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling

Okumoto, K., Misono, S., Miyata, N., Matsumoto, Y., Mukai, S. & Fujiki, Y., Aug 1 2011, In : Traffic. 12, 8, p. 1067-1083 17 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Cytochrome P-45017α in β-cells of rat pancreas and its local steroidogenesis

Ogishima, T., Mitani, F. & Suematsu, M., Jul 1 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 111, 1-2, p. 80-86 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Cytocidal actions of parasporin-2, an anti-tumor crystal toxin from Bacillus thuringiensis

Kitada, S., Abe, Y., Shimada, H., Kusaka, Y., Matsuo, Y., Katayama, H., Okumura, S., Akao, T., Mizuki, E., Kuge, O., Sasaguri, Y., Ohba, M. & Ito, A., Sep 8 2006, In : Journal of Biological Chemistry. 281, 36, p. 26350-26360 11 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
15 Citations (Scopus)

Design and synthesis of artificial ladder-shaped polyethers for exploring biological functions

Oishi, T., Jan 1 2019, In : Heterocycles. 99, 1, p. 21-53 33 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents

Torikai, K., Koga, R., Liu, X., Umehara, K., Kitano, T., Watanabe, K., Oishi, T., Noguchi, H. & Shimohigashi, Y., Jan 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 20, p. 5216-5237 22 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Designed modification of partial agonist of ORL1 nociceptin receptor for conversion into highly potent antagonist

Li, J., Isozaki, K., Okada, K., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., Mar 1 2008, In : Bioorganic and Medicinal Chemistry. 16, 5, p. 2635-2644 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Detection of Rap1A as a yessotoxin binding protein from blood cell membranes

Ujihara, S., Oishi, T., Mouri, R., Tamate, R., Konoki, K., Matsumori, N., Murata, M., Oshima, Y., Sugiyama, N., Tomita, M. & Ishihama, Y., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6443-6446 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro

Vecchiola, A., Lagos, C. F., Fuentes, C. A., Allende, F., Campino, C., Valdivia, C., Tapia-Castillo, A., Ogishima, T., Mukai, K., Owen, G., Solari, S., Carvajal, C. A. & Fardella, C. E., Aug 13 2013, In : Reproductive Biology and Endocrinology. 11, 1, 76.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Direct evidence revealing structural elements essential for the high binding ability of bisphenol a to human estrogen-related receptor-γ

Okada, H., Tokunaga, T., Liu, X., Takayanagi, S., Matsushima, A. & Shimohigashi, Y., Jan 1 2008, In : Environmental Health Perspectives. 116, 1, p. 32-38 7 p.

Research output: Contribution to journalArticle

286 Citations (Scopus)

Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors

Masuya, T., Iwamoto, M., Liu, X. & Matsushima, A., Dec 1 2019, In : Scientific reports. 9, 1, 9954.

Research output: Contribution to journalArticle

Open Access

Discriminatory synergistic effect of Trp-substitutions in superagonist [(Arg/Lys)14, (Arg/Lys)15]nociceptin on ORL1 receptor binding and activation

Nishimura, H., Li, J., Isozaki, K., Okada, K., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., Aug 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 15, p. 5683-5687 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Distinction of the binding modes for human nuclear receptor ERRγ between bisphenol A and 4-hydroxytamoxifen

Liu, X., Matsushima, A., Okada, H. & Shimohigashi, Y., Aug 1 2010, In : Journal of biochemistry. 148, 2, p. 247-254 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Donor Ligand Effect in Asymmetric Epoxidation of Unfunctionalized Olefins with Chiral Salen Complexes

Irie, R., Ito, Y. & Katsuki, T., Apr 1991, In : Synlett. 1991, 4, p. 265-266 2 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)

Double-labelled in situ hybridization reveals the lack of co-localization of mRNAs for the circadian neuropeptide PDF and FMRFamide in brains of the flies Musca domestica and Drosophila melanogaster

Matsushima, A., Takano, K., Yoshida, T., Takeda, Y., Yokotani, S., Shimohigashi, Y. & Shimohigashi, M., Jun 1 2007, In : Journal of biochemistry. 141, 6, p. 867-877 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Otera, H., Miyata, N., Kuge, O. & Mihara, K., Jan 1 2016, In : Journal of Cell Biology. 212, 5, p. 531-544 14 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
20 Citations (Scopus)

Edge-to-face CH/π interaction between ligand Phe-phenyl and receptor aromatic group in the thrombin receptor activation

Matsushima, A., Fujita, T., Nose, T. & Shimohigashi, Y., Jan 1 2000, In : Journal of biochemistry. 128, 2, p. 225-232 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria

Ito, A., Ogishima, T., Ou, W., Omura, T., Aoyagi, H., Lee, S., Mihara, H. & Izumiya, N., Jan 1 1985, In : Journal of Biochemistry. 98, 6, p. 1571-1582 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Enantioselective Epoxidation of 2,2-Dimethylchromenes Using Achiral Mn-Salen Complex as a Catalyst in the Presence of Chiral Amine

Hashihayata, T., Ito, Y. & Katsuki, T., 1996, In : Synlett. 1996, 11, p. 1079-1081 3 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Enantioselective epoxidation of olefins with chiral (salen)manganese(III) complexes bearing 4-methyl-3-[(R)-1-phenylpropyl]salicylideneamine as a constituent

Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Enantioselective epoxidation of olefins with chiral (Salen)manganese(III) complexes bearing 4-Methyl-3-[(R)-l-phenylpropyl] salicylideneamine as a constituent

Hosoya, N., Ine, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Enantioselective epoxidation of unfunctionalized olefins using chiral (salen)manganese(III) complexes

Irie, R., Noda, K., Ito, Y. & Katsuki, T., Feb 18 1991, In : Tetrahedron Letters. 32, 8, p. 1055-1058 4 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

Endocrine disrupter bisphenol a increases in situ estrogen production in the mouse urogenital sinus

Arase, S., Ishii, K., Igarashi, K., Aisaki, K., Yoshio, Y., Matsushima, A., Shimohigashi, Y., Arima, K., Kanno, J. & Sugimura, Y., Apr 1 2011, In : Biology of Reproduction. 84, 4, p. 734-742 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor γ (ERRγ) with high constitutive activity

Takayanagi, S., Tokunaga, T., Liu, X., Okada, H., Matsushima, A. & Shimohigashi, Y., Dec 1 2006, In : Toxicology Letters. 167, 2, p. 95-105 11 p.

Research output: Contribution to journalArticle

246 Citations (Scopus)

Enthalpy- and/or entropy-controlled asymmetric oxidation: Stereocontrolling factors in Mn-salen-catalyzed oxidation

Nishida, T., Miyafuji, A., Ito, Y. N. & Katsuki, T., Sep 2 2000, In : Tetrahedron Letters. 41, 36, p. 7053-7058 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Enzymatic synthesis of ω-amino-ceramide: Preparation of a sensitive fluorescent substrate for ceramidase

Tani, M., Kita, K., Komori, H., Nakagawa, T. & Ito, M., Oct 15 1998, In : Analytical Biochemistry. 263, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae

Watanabe, T., Tani, M., Ishibashi, Y., Endo, I., Okino, N. & Ito, M., Apr 14 2015, In : Glycobiology. 25, 10, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

ERRγ tethers strongly bisphenol A and 4-α-cumylphenol in an induced-fit manner

Matsushima, A., Teramoto, T., Okada, H., Liu, X., Tokunaga, T., Kakuta, Y. & Shimohigashi, Y., Aug 29 2008, In : Biochemical and Biophysical Research Communications. 373, 3, p. 408-413 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Exploration of the role of phenylalanine in the thrombin receptor tethered-ligand peptide by substitution with a series of trifluorophenylalanines

Matsushima, A., Fujita, T., Okada, K., Shirasu, N., Nose, T. & Shimohigashi, Y., Nov 1 2000, In : Bulletin of the Chemical Society of Japan. 73, 11, p. 2531-2538 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Expression of budding yeast IPT1 produces mannosyldiinositol phosphorylceramide in fission yeast and inhibits cell growth

Nakase, M., Tani, M. & Takegawa, K., May 1 2012, In : Microbiology. 158, 5, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol a in the human nuclear receptor estrogen-related receptor γ

Liu, X., Matsushima, A., Nakamura, M., Costa, T., Nose, T. & Shimohigashi, Y., Apr 1 2012, In : Journal of biochemistry. 151, 4, p. 403-415 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Flow synthesis of (3R)- and (3S)-(E)-1-iodohexa-1,5-dien-3-ol: Chiral building blocks for natural product synthesis

Katayama, S., Koge, T., Katsuragi, S., Akai, S. & Oishi, T., Jan 1 2018, In : Chemistry Letters. 47, 9, p. 1116-1118 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

FMP30 is required for the maintenance of a normal cardiolipin level and mitochondrial morphology in the absence of mitochondrial phosphatidylethanolamine synthesis

Kuroda, T., Tani, M., Moriguchi, A., Tokunaga, S., Higuchi, T., Kitada, S. & Kuge, O., Apr 1 2011, In : Molecular Microbiology. 80, 1, p. 248-265 18 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Fractionation of mammalian tissue mRNAs by high-performance gel filtration chromatography

Ogishima, T., Okada, Y. & Omura, T., May 1 1984, In : Analytical Biochemistry. 138, 2, p. 309-313 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Functional analysis of Chinese hamster phosphatidylserine synthase 1 through systematic alanine mutagenesis

Ohsawa, T., Nishijima, M. & Kuge, O., Aug 1 2004, In : Biochemical Journal. 381, 3, p. 853-859 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase

Kitada, S., Kojima, K., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32547-32553 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Glycine-rich region of mitochondrial processing peptidase α-subunit is essential for binding and cleavage of the precursor proteins

Nagao, Y., Kitada, S., Kojima, K., Toh, H., Kuhara, S., Ogishima, T. & Ito, A., Nov 3 2000, In : Journal of Biological Chemistry. 275, 44, p. 34552-34556 5 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Guest responsivity of a two-dimensional coordination polymer incorporating a cholesterol-based co-ligand

Kajitani, K., Koshiyama, T., Hori, A., Ohtani, R., Mishima, A., Torikai, K., Ebine, M., Oishi, T., Takata, M., Kitagawa, S. & Ohba, M., Dec 7 2013, In : Dalton Transactions. 42, 45, p. 15893-15897 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Haeme-regulated degradation of δ-aminolevulinate synthase 1 in rat liver mitochondria

Yoshino, K., Munakata, H., Kuge, O., Ito, A. & Ogishima, T., Oct 1 2007, In : Journal of biochemistry. 142, 4, p. 453-458 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)