Organic and Biological Chemistry

Research Output

2000

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

Fujita, T., Nose, T., Matsushima, A., Okada, K., Asai, D., Yamauchi, Y., Shirasu, N., Honda, T., Shigehiro, D. & Shimohigashi, Y., Feb 5 2000, In : Tetrahedron Letters. 41, 6, p. 923-927 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
1999
8 Citations (Scopus)

Asymmetric catalysis of new generation chiral metallosalen complexes

Ito, Y. & Katsuki, T., Apr 1 1999, In : Bulletin of the Chemical Society of Japan. 72, 4, p. 603-619 17 p.

Research output: Contribution to journalArticle

205 Citations (Scopus)

cis-selective aziridination of cis- or trans-α,β-unsaturated amides using diaziridine

Hori, K., Sugihara, H., Ito, Y. N. & Katsuki, T., Jul 9 1999, In : Tetrahedron Letters. 40, 28, p. 5207-5210 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Importance of ligand Phe-phenyl group for activation of thrombin receptor

Fujita, T., Nose, T., Matsushima, A., Costa, T. & Shimohigashi, Y., 1999, Peptide Science 1998. p. 33-36

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

22 Citations (Scopus)

Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide

Tani, M., Okino, N., Mitsutake, S. & Ito, M., 1999, In : Journal of Biochemistry. 125, 4, p. 746-749 4 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
1998

Cooperative formation of a substrate binding pocket by α- and β- subunits of mitochondrial processing peptidase

Kojima, K., Kitada, S., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32542-32546 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Enzymatic synthesis of ω-amino-ceramide: Preparation of a sensitive fluorescent substrate for ceramidase

Tani, M., Kita, K., Komori, H., Nakagawa, T. & Ito, M., Oct 15 1998, In : Analytical Biochemistry. 263, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase

Kitada, S., Kojima, K., Shimokata, K., Ogishima, T. & Ito, A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32547-32553 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
16 Citations (Scopus)

Purification and characterization of a novel ceramidase from pseudomonas aeruginosa

Okino, N., Tani, M., Imayama, S. & Ito, M., Jun 5 1998, In : Journal of Biological Chemistry. 273, 23, p. 14368-14373 6 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Role of α-subunit of mitochondrial processing peptidase in substrate recognition

Shimokata, K., Kitada, S., Ogishima, T. & Ito, A., Sep 25 1998, In : Journal of Biological Chemistry. 273, 39, p. 25158-25163 6 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
62 Citations (Scopus)
1997

Processing of mitochondrial protein precursors

Ito, A., Ogishima, T. & Kitada, S., Jan 1 1997, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 42, 14 Suppl, p. 2362-2367 6 p.

Research output: Contribution to journalReview article

Remarkable solvent effect on the enantioface selectivity in the Diels- Alder reaction catalyzed by an aluminum complex of a newly prepared chiral menthol derivative

Naraku, G., Hori, K., Ito, Y. & Katsuki, T., Nov 24 1997, In : Tetrahedron Letters. 38, 47, p. 8231-8232 2 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Substrate recognition by mitochondrial processing peptidase toward the malate dehydrogenase precursor

Shimokata, K., Nishio, T., Song, M. C., Kitada, S., Ogishima, T. & Ito, A., Jan 1 1997, In : Journal of biochemistry. 122, 5, p. 1019-1023 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Synthetic study of ciguatoxin. Absolute configuration of the C2 hydroxy group

Oguri, H., Hishiyama, S., Sato, O., Oishi, T., Hirama, M., Murata, M., Yasumoto, T. & Harada, N., Mar 3 1997, In : Tetrahedron. 53, 9, p. 3057-3072 16 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

The first asymmetric epoxidation using a combination of achiral (salen)manganese(III) complex and chiral amine

Hashihayata, T., Ito, Y. & Katsuki, T., Jul 14 1997, In : Tetrahedron. 53, 28, p. 9541-9552 12 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
1996

Cloning, expression and characterization of plasma platelet-activating factor-acetylhydrolase from guinea pig

Karasawa, K., Kuge, O., Kawasaki, K., Nishijima, M., Nakano, Y., Tomita, M., Yokoyama, K., Setaka, M. & Nojima, S., Jan 1 1996, In : Journal of biochemistry. 120, 4, p. 838-844 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Enantioselective Epoxidation of 2,2-Dimethylchromenes Using Achiral Mn-Salen Complex as a Catalyst in the Presence of Chiral Amine

Hashihayata, T., Ito, Y. & Katsuki, T., 1996, In : Synlett. 1996, 11, p. 1079-1081 3 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Role of basic amino acids in the cleavage of synthetic peptide substrates by mitochondrial processing peptidase

Song, M. C., Shimokata, K., Kitada, S., Ogishima, T. & Ito, A., Jan 1 1996, In : Journal of biochemistry. 120, 6, p. 1163-1166 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
1995

Analysis of elements in the substrate required for processing by mitochondrial processing peptidase

Ogishima, T., Niidome, T., Shimokata, K., Kitada, S. & Ito, A., Dec 22 1995, In : Journal of Biological Chemistry. 270, 51, p. 30322-30326 5 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

A putative metal-binding site in the β subunit of rat mitochondrial processing peptidase is essential for its catalytic activity

Kitada, S., Shimokata, K., Niidome, T., Ogishima, T. & Ito, A., Jan 1 1995, In : Journal of biochemistry. 117, 6, p. 1148-1150 3 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

COP-coated vesicles in intracellular protein transport

Kuge, O. & Kuge, S., Dec 1995, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 40, 16, p. 2427-2435 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

New convenient, enantiospecific synthesis of (S,S)- and (R,R)-2,2′-bipyrrolidine derivatives

Kotsuki, H., Kuzume, H., Gohda, T., Fukuhara, M., Ochi, M., Oishi, T., Hirama, M. & Shiro, M., Sep 1995, In : Tetrahedron: Asymmetry. 6, 9, p. 2227-2236 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
1994

A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: Histochemical detection and possible physiological role

Mitani, F., Suzuki, H., Hata, J. I., Ogishima, T., Shimada, H. & Ishimura, Y., Jul 1994, In : Endocrinology. 135, 1, p. 431-438 8 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)

Arginine residues in the extension peptide are required for cleavage of a precursor by mitochondrial processing peptidase. Demonstration using synthetic peptide as a substrate

Niidome, T., Kitada, S., Shimokata, K., Ogishima, T. & Ito, A., Jan 1 1994, In : Journal of Biological Chemistry. 269, 40, p. 24719-24722 4 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Ten-membered neocarzinostatin chromophore analogs leading to σ,σ-biradical via a cumulene intermediate

Kawata, S., Oishi, T. & Hirama, M., Jun 27 1994, In : Tetrahedron Letters. 35, 26, p. 4595-4598 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1993

A formal synthesis of aplysiatoxin: enantioselective synthesis of kishi's aldehyde

Okamura, H., Kuroda, S., Ikegami, S., Tomita, K., Sugimoto, Y. I., Sakaguchi, S. I., Ito, Y., Katsuki, T. & Yamaguchi, M., 1993, In : Tetrahedron. 49, 46, p. 10531-10554 24 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Asymmetric aziridination by using optically active (Salen)manganese(III) complexes

Noda, K., Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., Jul 1993, In : Synlett. 1993, 7, p. 469-471 3 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Chiral Leaving Group: Synthesis of Optically Active Benzimidazole and its Application to Asymmetric Acylation

Ogata, M., Yoshimura, T., Fujii, H., Ito, Y. & Katsuki, T., Oct 1993, In : Synlett. 1993, 10, p. 728-730 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Molecular Cloning of the Smaller Subunit (P52) of Rat Liver Mitochondrial Processing Protease

Kitada, S., Niidome, T., Nagano, T., Ogishima, T. & Ito, A., Jan 1 1993, In : Biochemical and Biophysical Research Communications. 190, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Synthesis of the 1β-Methylcarbapenem Key Intermediates

Ito, Y. & Terashima, S., Jan 1 1993, Studies in Natural Products Chemistry. p. 145-177 33 p. (Studies in Natural Products Chemistry; vol. 12).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

Kuge, O., Hara-Kuge, S., Orci, L., Ravazzola, M., Amherdt, M., Tanigawa, G., Wieland, F. T. & Rothman, J. E., Dec 1 1993, In : Journal of Cell Biology. 123, 6 II, p. 1727-1734 8 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
1992

Highly Enantioselective Epoxidation of 2,2-Dimethylchromenes

Hatayama, A., Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., May 1992, In : Synlett. 1992, 5, p. 407-409 3 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
1991

A formal total synthesis of aplysiatoxin

Okamura, H., Kuroda, S., Ikegami, S., Ito, Y., Katsuki, T. & Yamaguchi, M., Sep 16 1991, In : Tetrahedron Letters. 32, 38, p. 5141-5142 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Catalytic asymmetric epoxidation of unfunctionalized olefins using chiral (salen)manganese(III) complexes

Irie, R., Noda, K., Ito, Y., Matsumoto, N. & Katsuki, T., 1991, In : Tetrahedron: Asymmetry. 2, 7, p. 481-494 14 p.

Research output: Contribution to journalArticle

177 Citations (Scopus)

Catalytic epoxidation with molecular oxygen using nickel complex

Irie, R., Ito, Y. & Katsuki, T., Nov 18 1991, In : Tetrahedron Letters. 32, 47, p. 6891-6894 4 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Donor Ligand Effect in Asymmetric Epoxidation of Unfunctionalized Olefins with Chiral Salen Complexes

Irie, R., Ito, Y. & Katsuki, T., Apr 1991, In : Synlett. 1991, 4, p. 265-266 2 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)

Enantioselective epoxidation of olefins with chiral (salen)manganese(III) complexes bearing 4-methyl-3-[(R)-1-phenylpropyl]salicylideneamine as a constituent

Hosoya, N., Irie, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Enantioselective epoxidation of olefins with chiral (Salen)manganese(III) complexes bearing 4-Methyl-3-[(R)-l-phenylpropyl] salicylideneamine as a constituent

Hosoya, N., Ine, R., Ito, Y. & Katsuki, T., Jan 1 1991, In : Synlett. 1991, 10, p. 691-692 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Enantioselective epoxidation of unfunctionalized olefins using chiral (salen)manganese(III) complexes

Irie, R., Noda, K., Ito, Y. & Katsuki, T., Feb 18 1991, In : Tetrahedron Letters. 32, 8, p. 1055-1058 4 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)
1990

Catalytic asymmetric epoxidation of unfunctionalized olefins

Irie, R., Noda, K., Ito, Y., Matsumoto, N. & Katsuki, T., 1990, In : Tetrahedron Letters. 31, 50, p. 7345-7348 4 p.

Research output: Contribution to journalArticle

620 Citations (Scopus)
1985

Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria

Ito, A., Ogishima, T., Ou, W., Omura, T., Aoyagi, H., Lee, S., Mihara, H. & Izumiya, N., Jan 1 1985, In : Journal of Biochemistry. 98, 6, p. 1571-1582 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Import and processing of the precursor of cytochrome P-450(SCC) by bovine adrenal cortex mitochondria

Ogishima, T., Okada, Y. & Omura, T., Jan 1 1985, In : Journal of biochemistry. 98, 3, p. 781-791 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
1984

Fractionation of mammalian tissue mRNAs by high-performance gel filtration chromatography

Ogishima, T., Okada, Y. & Omura, T., May 1 1984, In : Analytical Biochemistry. 138, 2, p. 309-313 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Presence of a prepiece at the NH2-terminai end of pre-cytochrome P-450(SCC) peptide

Ogishima, T., Okada, Y. & Omura, T., Jan 1 1984, In : Journal of biochemistry. 95, 5, p. 1525-1528 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
1983

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome p-450's from adrenal cortex

Ogishima, T., Okada, Y., Kominami, S., Takemori, S. & Omura, T., Nov 1983, In : Journal of Biochemistry. 94, 5, p. 1711-1714 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)